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CROP MYCOSIS (THRUSH, CANDIDIASIS) Most common mycotic diseases of poultry Most important in young poults and occasionally cage layers

CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

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Page 1: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

CROP MYCOSIS (THRUSH,

CANDIDIASIS)

• Most common mycotic diseases of poultry

• Most important in young poults and occasionally

cage layers

Page 2: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

ETIOLOGY

Candida albicans

• Very ubiquitous in normal flora

• Follows debilitating condition

• Broad spectrum antibiotics favor development by disruption

of normal flora balance.

• Seen in “spiking mortality” poults due to antibiotic use.

Page 3: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

INCUBATION PERIOD

• Experimentally about 30 days, but has been

found in 7-14 day old poults

• Induced by giving sugar water to poults.

Page 4: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

COURSE OF DISEASE

• 3 to 4 weeks

• May become chronic, then

several weeks

Page 5: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

MORTALITY

• Poults and chicks - up to 20 to 30%

• Older birds - after 4 weeks usually low

Page 6: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

METHOD OF SPREAD

1. Drinking water

a) associated with unsanitary, over-crowded

condition

b) slimy water founts, wet litter

2. Infected birds source of contamination

3. Cages due to decreased bacterial competition

No contact with feces.

Page 7: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

SYMPTOMS

• Poor growth

• "Sick chick attitude"

• In layers - decrease egg production 15 to

20%

• Birds vomit in feed trough

Page 8: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

POSTMORTEM LESIONS

• Non-inflammatory - thickened crop and/or mouth

• White, circular, raised ulcer-like formation

• Pseudomembrane

• Proventriculitis

Gizzard erosion

• Can occasionally be cultured from the liver.

• May cause splotchy hemorrhages in the digestive tract.

Page 9: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

Crop mycosis

Page 10: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

Crop mycosis

Page 11: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

Crop mycosis

Page 12: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

Crop mycosis

Page 13: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

Esophageal lesion

Page 14: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

Gizzard erosion

Page 15: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

Enteritis

Page 16: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

DIAGNOSIS

• Suggestive - typical lesions, non-inflammatory

• Positive - isolation and identification

– Special medias used:

• Corn meal agar

• Biggy agar - brown colony with white halo

Page 17: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

Biggy agar

Page 18: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

Wet mount

Page 19: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

TREATMENT

Mycostatin (nystatin)

100 gm/ton 7-10 days

CuSO4

1:2000 in water, 1-3 #/ton

Chlorine in the drinking water at 5 ppm.

Clean up

Page 20: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora

PREVENTION

• Maintain sanitation

• Avoid prolonged use of broad spectrum antibiotics

• Mycostatin (nystatin) in feed 50 gm/ton

• Ca++ or Na+ propionate in feed 3-5 #/ton

• Propionic acid antifungals in feed 1-4 #/ton.

(Depends on concentration of active ingredient).

Page 21: CROP MYCOSIS (THRUSH, CANDIDIASIS)• Very ubiquitous in normal flora • Follows debilitating condition • Broad spectrum antibiotics favor development by disruption of normal flora