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Cubist Pharmaceuticals, in collaboration

with Northeastern University School of

Pharmacy, is pleased to offer two-year

post doctoral fellowships with opportuni-

ties in Clinical Research, Marketing and

Medical Affairs.

AbAbout

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AbCubist PharmaceuticalsCubist Pharmaceuticals is a biopharmaceutical company focused on the research,development, and commercialization of pharmaceutical products that address significant unmetmedical needs in the acute care environment. Based in Lexington, MA, Cubist currently employsover 900 people, with 600 employees in Massachusetts. Cubist markets products for Gram- positive infections, gastrointestinal recovery, and Clostridium difficile-associated diarrhea. Cubist has also partnered to promote others’ products in the infectious disease space. Cubist’s acquisition of Trius Therapeutics and Optimer Pharmaceuticals also marks an important milestone, bolstering its leadership in acute care.

Cubist’s clinical product pipeline currently consists of a Phase 3 program focused on the development of a novel cephalosporin to address certain serious infections caused by multi-drug resistant (MDR) Gram-negative organisms, a Phase 3 program for the treatment of Clostridium difficile-associated diarrhea (CDAD), and a Phase 3 program for the treatment of chronic opioid induced constipation (OIC) in patients with chronic non-cancer pain. Cubist also is working on several pre-clinical programs being developed to address areas of significant

medical need, including therapies to treat various serious bacterial infections.

Today, Cubist partners with other pharmaceutical companies to make our products available outside the U.S. in more than 70 countries, and the list continues to grow. Since 2008, Cubist has awarded more than $1.4 million to nonprofit organizations with programs that are inspiring young minds to pursue careers in Science, Technology, Engineering & Mathematics (STEM) fields and providing ways for teachers to incorporate creative techniques in their classrooms.

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Cubist Recognition

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Northeastern UniversityAt Northeastern, we make a meaningful impact in both our local communities and the world by us-ing our knowledge and resources as forces of change. Through a collaborative approach involving partnerships between government, industry, artists, innovators, scholars, and through the translation of fundamental research into applications, we contribute to economic development and enhance societal well-being.

At Northeastern we encourage our students to become engaged citizens of the world, confident and resourceful people who realize that their knowledge and actions have positive effects on their own lives and those of others. Students ignite their passion for learning and are exposed to the endless possibilities around them through transformative experiential education. The School of Pharmacy provides a dynamic academic environment to guide and support fellows toward successful careers in the biopharmaceutical industry and offers the opportunity to gain teaching and research experiences in an academic setting. The faculty and Cubist program leaders mentor fellows according to the fellows’ scholarly and professional interests throughout the two year program. As visiting scholars at the School of Pharmacy, fellows will:

▪ Participate in teaching courses, seminars and laboratories

▪ Co-precept students on advanced pharmacy practice experiences

▪ Create and publish scholarly research and review articles

▪ Present research at scientific and clinical meetings

▪ Participate in professional development seminars with other fellows and residents

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Abthe AreaWhile considered a hub of academia because of its many institutions of higher education and commitment to intellectual curiosity and achievement, Boston is more than just the sum of its colleges and universities. Boston is an evening stroll through Beacon Hill, a morning row on the Charles River, an afternoon of people-watching in Quincy Market, or an adventure through time while tracing the steps of the American Revolution along the Freedom Trail. It’s Opening Day at Fenway Park, high-end shopping on Newbury Street, alfresco dining in the North End, and dancing and nightlife on Landsdowne Street.

Boston is many things to those who live here, but above all, it is a vibrant city that feeds off its own diversity. You feel it as much on the sidewalks as you do in the city’s cultural institutions and ethnic celebrations. Bordered by the Atlantic Ocean on the east, Boston is situated in mid-New England within driving distance of other prominent cities such as: Portland, Maine; Providence, Rhode Island; Hartford, Connecticut; and New York, New York.

Cubist Pharmaceuticals is headquartered in Lexington, MA, approximately 15 miles from Northeastern University, which is located in the heart of Boston.

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the FellowshipThe fellowship program is designed to offer Doctor of Pharmacy graduates an in-depthexperience in a biopharmaceutical industry setting.

Fellows will be appointed as visiting scholars and will participate in teaching and precepting at Northeastern’s School of Pharmacy. Fellows will also attend and participate in teaching seminars where they will interact with pharmacy residents and fellows from throughout Massachusetts. Additionally, fellows will have the opportunity to publish at least one article per fellowship year, present data at scientific conferences, and assist in precepting students on advanced pharmacy practice experiences.

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Overall Objectives ▪ Enhance professional growth in both biopharmaceutical industry and academia

▪ Enhance project management, teamwork and leadership skills

▪ Perform critical analysis and synthesis of medical literature

▪ Improve the ability to expertly communicate scientific concepts, ideas and information both in writing and via formal presentation

▪ Participate on cross-functional teams supporting the research, development and commercialization of Cubist’s products

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Pr ▪ Present disease state, product and therapeutic information at internal and external meetings

▪ Gain exposure to Legal Medical Review (LMR) committee & participate in Promotional and Scientific Review Committees (PSRC)

▪ Expand clinical knowledge, teaching experience, and performance evaluation skills through participation in core curricular and specialty elective courses at Northeastern University School of Pharmacy

▪ Submit one peer-reviewed publication or one abstract presentation at a national and/or regional meeting per fellowship year

▪ Attend monthly seminars and participate in the teaching certificate program at Northeastern University

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Program InformationClinical ResearchThe Clinical Research fellow will gain experience in drug development by working on all phases of clinical trials ranging from first-in-human Phase 1 studies through Phase 3 and post-approval studies. The fellow will interact as a scientific liaison with external researchers and Cubist study teams to contribute to clinical studies from the planning and approval stages, through study completion and post-study closure. This clinical perspective is crucial to data interpretation and directly contributes to the methodology for design and execution of clinical protocols and final reports.

Clinical Research is focused on the development of new pipeline products and on innovative research with existing products. While playing a key role in Cubist’s Clinical Research team, the fellow will also collaborate with many other departments, functioning as an active member of several multidisciplinary teams to design and execute U.S. and global clinical trials.

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FUNCTIO

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TEAMS

EARLY AND

LATE STAGE

DEVELO

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CLINICALOPERATIONS

PHARMACOVIGILANCE

BIOSTATISTICS

STATISTICAL PROGRAMMING

BUSINESS DEVELOPMENT

MEDICAL AFFAIRS

REGULATORYAFFAIRS

PHASE 1First in humans safety and PK/PD

PHASE 2Proof of efficacy

PHASE 3Pivotal trialsto enable NDA

PHASE 4Post approval studies

CLINICAL RESEARCH

PrThey will work with other members of the brand team to ensure all promotional materials and tools are aligned with scientific messaging and strategy. Fellows will interact closely with Medical Affairs and Clinical Development to identify potential gaps in current plans and develop initiatives to address those gaps. They will also participate on cross-functional life cycle management teams to support the commercialization of Cubist’s products. Fellows will have the opportunity to lead and participate in projects in other departments based on interest and company need to enhance learning and personal development.

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MarketingThe Marketing fellows will gain broad experience in the Commercial organization with a primary focus on scientific marketing strategy. Fellows will work with the product brand teams to develop the scientific brand plan, lead advisory boards, develop promotional medical education, and engage with key opinion leaders in the acute care community under the mentorship of the leadership team.

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TEAMS

SCOPE O

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ACTIVITIES

MEDICALAFFAIRS

CLINICALDEVELOPMENT

SALES TRAINING

REGULATORYAFFAIRS

LEGAL

PROGRAM ANDPORTFOLIO MANAGEMENT

MARKETING

SCIENTIFICBRAND PLAN

ADVISORYBOARDS

PROMOTIONALMEDICAL EDUCATION

CONGRESS PLAN

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Medical AffairsA Medical Affairs fellow will gain valuable experience as a key member of teams within various functional areas and departments under mentorship of Medical Affairs leadership. Fellows will have the flexibility to participate in activities based on interest and company needs in order to enhance learning and personal growth. These include, but are not limited to, projects within Global Medical Affairs (comprised of Medical Information, Medical Sciences, Operations, Field Medical Affairs, Scientific Training and Health Economics and Outcomes Research), departmental or company research, and competitive intelligence.

Fellows will join the Medical Information team and develop medical writing skills and provide accurate information about Cubist products to external customers. They will also have many unique opportunities to serve on committees that perform medical reviews of promotional materials, analyze published medical and scientific literature, and evaluate in-house product and disease state technical training. Fellows have the opportunity to work closely with Field Medical personnel (both internally at Cubist and externally), who collaborate with researchers and key opinion leaders (KOLs) in the acute care community.

Additionally, fellows can explore roles on the Health Economics and Outcomes Research team, which generates data that supports pipeline and marketed products. Through cross-functional involvement, fellows quickly become an integral part of the Medical Affairs team and gain experience in various areas within the pharmaceutical industry.

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ACTIVITIES

GLOBAL MEDICAL SCIENCES

HEALTH ECONOMICS AND OUTCOMES RESEARCH

FIELD MEDICAL AFFAIRS

GLOBAL MEDICAL INFORMATION AND TRAINING

ENTERPRISE-WIDE COLLABORATION ■ Commercial Organization ■ Regulatory Affairs ■ Clinical Development

MEDICALAFFAIRS

PIPELINE PRODUCTS

MARKETEDPRODUCTS

DISEASE STATE AWARENESS

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ACTIVITIES

GLOBAL MEDICAL SCIENCES

HEALTH ECONOMICS AND OUTCOMES RESEARCH

FIELD MEDICAL AFFAIRS

GLOBAL MEDICAL INFORMATION AND TRAINING

ENTERPRISE-WIDE COLLABORATION ■ Commercial Organization ■ Regulatory Affairs ■ Clinical Development

MEDICALAFFAIRS

PIPELINE PRODUCTS

MARKETEDPRODUCTS

DISEASE STATE AWARENESS

ElCubist and Northeastern University Elements

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El Cubist Pharmaceuticals is an acute carebiopharmaceutical company and is poised for an exciting future following the blockbuster

commercialization of an important life-saving product for resistant Gram-positive infections. Cubist has multiple marketed products in both the infectious disease and acute care space and is actively looking to expand its portfolio of marketed products. In addition, Cubist is entering a phase of aggressive pipeline building, from IND stage products through late phase development candidates. The opportunities for a post-doctoral fellow in Medical Affairs are vast and encompass everything from research and publications to scientific support of sales and marketing. Cubist is a small, growing, fast-paced, fluid company where a fellow can be exposed to a variety of exciting and career developing experiences. The skills and experience gained in this fellowship will be key to a successful future in the pharmaceutical industry.

Scott McConnell, PharmDSenior Director, Global Medical InformationCubist Pharmaceuticals Fellowship Director

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The Marketing program at Cubist provides the fellows with a unique opportunity to be involved in and lead challenging projects across the Commercial

organization. The fellow will gain valuable experiences by developing a scientific brand plan and collaborating with cross-functional teams to execute key initiatives to support the commercialization of our products. The preceptors and leadership team at Cubist will highly motivate and effectively enable the fellow to develop a comprehensive understanding of Marketing as well as many cross-functional departments within a rapidly growing pharmaceutical company. This program offers a tremendous opportunity for a healthcare professional to establish a strong foundation for a future career in the pharmaceutical industry.

Monica Crompton, PharmD Manager, MarketingCubist Pharmaceuticals Assistant Fellowship DirectorPast Fellow, 2008–2010

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”The Medical Affairs fellowship at Cubist is uniquely positioned to provide fellows with a tremendous and challenging opportunity for personal and professional

growth. It’s an exciting time of rapid growth at Cubist, and fellows are able to take on challenging projects and assume leadership roles that will set them up for success in future careers in the pharmaceutical industry. The fellows have the opportunity to gain a broad range of experience in various groups including Medical Information, Health Economics & Outcomes Research, Global Medical Affairs Strategy, and Field Medical Affairs. Fellows are truly integrated into cross functional teams, enabling them to achieve a comprehensive understanding of the role of Medical Affairs relative to other functional areas. This program offers an exceptional experience for PharmD fellows to learn and develop valuable skills that will enable them to pursue a rewarding career in the pharmaceutical industry.

Kelly Broderick, PharmDSenior Manager, Health Economics and Outcomes ResearchCubist Pharmaceuticals Medical Affairs Fellowship PreceptorPast Fellow, 2010-2012

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Northeastern University Bouvé College of Health Sciences School of Pharmacy programs, faculty

and research activities are grounded by a strong foundation in laboratory, translational, experiential teaching and research. Fellows will have the opportunity to be mentored by experienced faculty in speciality areas ranging from administrative and social sciences, health outcomes, communication, as well as clinical areas such as internal medicine, ambulatory care, critical care, infectious diseases, oncology and psychiatry. Opportunities for collaboration in didactic and experiential teaching, medical writing, and research with faculty members as mentors will allow fellows to explore various interest areas during the program. Real-life experience is the cornerstone of programs at Northeastern University and your fellowship program.

J. Andrew Skirvin, PharmD, BCOP Associate Clinical Professor Fellowship Coordinator

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ElCubist Pharmaceuticals provides a truly unique opportunity for a post-doctoral fellow to pursue

a challenging and dynamic career in the biopharmaceutical industry. The Clinical Research program here enables fellows to maximize and build upon clinical and management skills, while providing the confidence to function as an independent professional as part of a multi-disciplinary team. The fellow has the opportunity to act as a scientific liaison with researchers and study teams, contributing to all stages of ongoing clinical trials. Cubist offers a highly motivating work experience that will effectively enable the fellow to prepare for a successful career in the pharmaceutical industry.

Jennifer Huntington, PharmDPrincipal Clinical Research ScientistCubist Pharmaceuticals Clinical Research Fellowship PreceptorPast Fellow 2007–2009

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PROGRAMS ▪ Clinical Research ▪ Marketing ▪ Medical Affairs

ELIGIBILITYApplicants must be Doctor of Pharmacy candidates or graduates from an ACPE accredited institution prior to the start of the fellowship year, and must be bright and enthusiastic professionals with excellent communication and time-management skills. Fellows will be selected on a nationally competitive basis by the fellowship program directors at Cubist Pharmaceuticals and Northeastern University.

COMPENSATIONThe fellow will receive a competitive stipend along with comprehensive health and dental insurance and other benefits from Northeastern University.

CERTIFICATE OF COMPLETIONCubist Pharmaceuticals and Northeastern University will award fellows a certificate of achievement upon successful completion of the two year fellowship program.

PROGRAM DIRECTORS ▪ Cubist Pharmaceuticals Scott McConnell, PharmDMonica Crompton, PharmD

APPLICATION PROCESSParticipation at the ASHP Midyear Clinical Meeting Personnel Placement Service (PPS) is strongly encouraged. Application material must be received between December 1st and 31st.

APPLICATION MATERIAL ▪ Cover letter ▪ Curriculum vitae

PLEASE DIRECT QUESTIONS TO:

CUBISTFELLOWS@NEU.EDU

FOR APPLICATION SUBMISSION

INSTRUCTIONS, PLEASE VISIT:

HTTP://ISSUU.COM/CUBISTFELLOWSHIP

▪ Three letters of recommendation ▪ Official college transcript

▪ Northeastern School of PharmacyJ. Andrew Skirvin, PharmDDavid Zgarrick, PhD

Fellowship Program Application Process/Eligibility

Cubist Pharmaceuticals and Northeastern University School of Pharmacy Fellowship Program

CUBIST PHARMACEUTICALS65 Hayden Ave

Lexington, MA 02421

www.cubist.com

NORTHEASTERN UNIVERSITY 360 Huntington AveBoston, MA 02115

www.northeastern.edu