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1CURRICULUM IMC
CURRICULUM OF PATHOLOGYMBBS COURSE
Contents
S. No. Subject Page No.
1. Introduction 02
2. Educational Hours 03
3. Learning Outcomes 04
4. Educational Strategies 05
5. Assessment 06
6. Learning Resources 07
7. Contents Modules 08
8. Implimentation 09-11
9. Programme Evaluation 12
10. Table of Specification 13-19
11. Modules 20-37
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2CURRICULUM IMC
Pathology subject will be covered during third year and fourth year. Pathology is taught with its clinical application and use in clinical subjects. Due to nature of this subject educational strate-gies of diverse approaches are employed. Educational resources like videos, biological speci-mens, microscopy slides, books and journals are used to learn this diverse subject. Early clinical exposure is used for clinical application of Pathology.
Third year and fourth year are divided in three educational terms which conclude at with formative assessment test. End of year is University exam for summative assessment.
INTRODUCTION
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3CURRICULUM IMC
EDUCATIONAL HOURS
Year Theory Practical Total
3rd year 150 hours(100 Lecture, 50 SGD / PBL) 100 hours 250
4th year 150 hours(100 Lecture, 50 SGD / PBL) 100 hours 250
Total 300 hours in 36 weeks/year 200 hours 500 hours
Strategy
LecturesProblem based learningSmall group discussionCase based discussion
Laboratory sessionMicroscopy sessions
Clinical sessionsAudio video sessions
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4CURRICULUM IMC
LEARNING OUTCOMES
AT THE END OF CURRICULUM STUDENT WILL BE ABLE TO
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5CURRICULUM IMC
EDUCATION STRATEGIES
The educational strategies in this curriculum are multiple and aligned with domain of learning and according to the desired outcome
Interactive lecturesOne-third of the curriculum will be delivered in a traditional didactic format including PowerPoint presentations and case discussions. Didactic education is considered to be a one-way transmis-sion of material from teacher to learner, we cannot overlook the possibility of meaningful interac-tion between experts and learners during live lectures. This type of interaction, which allows for immediate clarification of concepts and extension of knowledge, may be particularly important for novice learners who have relatively little exposure to the subject matter, such as our study population.
Problem based learningA lot of emphasis is on case based discussion. Problem-based learning (PBL) is complex and heterogeneous. A wide variety of educational methods are referred as PBL. These include Lec-ture-based case, Case based lecture, Case based discussions, Problem or inquiry based and Closed loop or reiterative. Incorporation of case based discussion in teaching enhances the critical thinking and problem-solving skills. It also helps in developing a broader prospective of clinical case scenarios.
Small Group DiscussionSmall group discussion provides a unique environment to achieve high standards in medical edu-cation. Activation of prior knowledge, exchange of ideas, and engagement at a higher cognitive level are assumed to result in deeper learning and better academic achievements by students.
Video sessionsPathology is a subject which involves visual learning and formulating concepts. Video assisted learning sessions also provides opportunities to learn gross anatomy.
Laboratory SessionsLaboratory sessions are important as they provide opportunity for experiential learning in terms of study of slides and identification of tissues
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6CURRICULUM IMC
ASSESSMENT
MCQ’s and SEQ’sMultiple choice question and short essay question test will be used at the end of part of curric-ulum to assess the learning of knowledge. These all assessment exercises will be formative. The written tests like Multiple-Choice Questions (MCQs) and Short-Essay Questions (SEQs) test formats are used for the assessment of cognitive domain. The MCQs are more objective and essentially select type of item response format. MCQs have a cueing effect, which promotes guessing and leads to higher scores. In addition, writing MCQs of higher cognitive level of prob-lem solving is challenging. On the contrary, the SEQs are more subjective and have a supply or construct type item response format, which does not have any cueing effect and can effectively assess problem solving skills.
Clinical exam and OSCEShort case and OSCE will be used to evaluate clinical skills and procedural skills at the ward end of placement. The OSCE is a method of clinical skill assessment, and it has been reported to be appropriate for assessing learning achievement levels in the psychomotor and emotional domains, which are difficult to evaluate with written examinations.
Viva VoceViva voce is used for assessment of knowledge and problem solving ability of students. This method is useful evaluating cognitive domain.
AssignmentsStudents of different year will be given assignment of different nature such as research and liter-ature search and surveys
INTERNAL ASSESSMENT i. The weightage of internal assessment shall be 10% of totals marks. ii. Continuous internal assessment shall consist of evaluation at the end of each assignments,
e.g. stages/sub-stage, class tests etc., attitudinal assessment from educational supervisors. iii. Assessment of knowledge, Skills and Attitude shall contribute toward internal assessment.
Methods used to assess these domains shall include Multiple Choice Questions of one-best type, Short essay questions, Oral/Viva, and Practical/Clinical axaminations.
iv. The score of internal assessment shall contribute to the score in the final examination, Final university examination of each subject shall contribute 90 to total score, and the candidate shall pass in aggregate.
v. Proper record of continuous internal assessment shall be maintained.
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7CURRICULUM IMC
LEARNING RESOURCESThe department of pathology will require following resources for implementation resources:
• Human resource
• Instructors (faculty members)
• Curriculum coordinator curriculum secretary
• Infrastructure
• Lecture hall with AV aids
• Tutorial room with AV aids
• Museum with Patholgy Specimens
• Pathology Lab with Pool of slides
• Simulated patients and simulated manikins
• Computers
LISTS OF CONTENT RESOURCES• Pathological Basis of Disease by Kumar, Cortan and Robbins, 7th Ed., W.B. Saunders.
• Medical Microbiology and Immunology by Levinson and Jawetz, 9th Ed., Mc Graw-Hill.
• Medical Genetics by Jorde, 3rd Ed., Mosby.
• Clinical Pathology Interpretations by A. H. Nagi
• Pathological Basis of Disease by Kumar, Cotran, Robbins. 7th. Ed.
• Medical Microbiology and Immunology by Levinson and Jawetz, 9th Ed.
• Mc Graw-Hill
• Ackerman’s Surgical Pathology
• Clinical Pathology Interpretations by A.H. Nagi
• Theory and Practice Of Histololgical Techniques by John D Bancroft
• District Laboratory Practice in Tropical Countries by Monica Cheesburgh, 2nd Ed. Part I & II
• Online Journals and Reading Materials through HEC Digital Library Facility.
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8CURRICULUM IMC
S.No Topic
1 Module 1 Inflammation, Mediators of Inflammation
2 Module 2 Wound Healing
3 Module 3 Disorders of Circulation
4 Module 4 Microbiology
5 Module 5 Priciples of antimicrobial action
6 Module 6 Genetics
7 Module 7 Growth Disorders/Neoplasia
8 Module 8 Immunology
9 Module 9 Blood veseels & heart
10 Module 10 Hematopoietic and lymphoid systems
11 Module 11 Respiratory system
12 Module 12 Oral cavity and GIT
13 Module 13 Urinary System
14 Module 14 Male Genital system
15 Module 15 Female Genital system
16 Module 16 Breast
17 Module 17 Musculoskeletal system
18 Module 18 Endocrine system
19 Module 19 Nervous system
CONTENTS MODULES
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9CURRICULUM IMC
IMPLEMENTATIONThe curriculum will be spread over 2 year with 36 working weeks each year. During this period student will be exposed to various education strategies to achieve the learning objectives.
3rd Year.In this year student will be exposed to do clinical laboratory, blood bank and Museum to develop understanding of general pathology and its applied aspects.
Theory (Lecture, SGD and PBL) Practical (Early clinical exposure, Histo-Lab, Museum)
150 Hours (36 Weeks) 100 Hours
4th Year.In this year student will be exposed to do clinical laboratory, blood bank and Museum to develop understanding of special pathology and its applied aspects.
Theory (Lecture, SGD and PBL) Practical (Early clinical exposure, Histo-Lab, Museum)
150 Hours (36 Weeks) 100 Hours
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10CURRICULUM IMC
First Year
First term Second term Third term
Gross anatomy
Histology
Embryology
General Anatomy
Assessment
Third Year
First term Second term Third term
1st Term
2nd Term
3rd Term
Assessment
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11CURRICULUM IMC
Fourth Year
First term Second term Third term
1st Term
2nd Term
3rd Term
Assessment
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12CURRICULUM IMC
PROGRAMME EVALUATIONPurpose of Evaluation The major goals of the evaluation are to provide information that the students can use to achieve curricular objectives and that the faculty can use to monitor quality of and improve curriculum.
Design of Evaluation The evaluation design as only posttest.
Users of evaluation: students, curriculum faculty, Principal OfficeResources: Curriculum faculty and departmental secretaries. No additional funding
Evaluation question: • What percentage of students achieved 75% mandatory attendance?• What percentage of students achieved pass marks in university exam?• What are the strengths of the curriculum? What are the weaknesses? How can the curriculum
can be improved?
Because of limited resources, the evaluation was kept simple. Data Collection was integrated into the curriculum schedule. The major goals of the evaluation are to provide information that the students can use to achieve curricular objectives and that the faculty can use to monitor quality of and improve curriculum. The evaluation design as only posttest.
End of curriculum evaluation form:This will be filled by students and faculty members for evaluation of adequacy with each content was covered, whether they would recommend the curriculum to others and written comments on curriculum strengths, weaknesses and suggestions for improvements.
Annual Report:Based on evaluation of the educational programe report will be generated annually and submitted to Medical Educational Department.
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13CURRICULUM IMC
GENERAL PATHOLOGY AND MICROBIOLOGY
TABLE OF SPECIFICATION (ToS)Sr. No. Topic Specification MCQ’s
1 Cell Injury 04
2 Inflammation and Mediators of inflammation 06
3 Healing and Repair 02
4 Disorder Of Circulation 04
5 Parasitology 05
6 Virology 06
7 General Bacteriology 04
8 Special Bacteriology 14
9 Mycology (Fungi) 04
10 Genetics 02
11 Disorders of Growth 09
12 Immunology 05
Total 65
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14CURRICULUM IMC
GENERAL PATHOLOGY AND MICROBIOLOGY
TABLE OF SPECIFICATION (ToS)Sr. No. Topic Specification SEQ’s
1 Acute and Chronic Inflammation 01
2 Cellular Adaptations, Cellular injury and Cell Death 01
3 Inflammation and Repair 01
4 Disorders of Circulation 01
5 Genetic Disorders 01
6 Neoplasma 01
7 Immunology 01
8 Bacteriology 03
9 Bacteriology (Mycobacteria) 01
10 Parasitology 01
11 Mycology 01
12 Virology 01
Total 14
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15CURRICULUM IMC
GENERAL PATHOLOGY AND MICROBIOLOGY
General Pathology 7 Stations Microbiology 9 Stations Observe 7 Station Total 20 Station
TABLE OF SPECIFICATION (ToS for OSPE)Sr. No. Topic No. of Staion
1 Acute and Chronic Inflammation 01
2 Cellular Adaptations, Cellular injury and Cell Death 01
3 Cellular Adaptations 01
4 Pigmentation / Intracellular accumulation / Calcification. 01
5 Neoplasia 02
6 Hemodynamics - Thrombosis, Embilism, Infarction, Congestion. 01
7 Culture Media 02
8 Gram stained slide 01
9 ZN Stained slide 01
10 Biochemical reaction 01
11 Photograph / Instrument / Report related to microbiology 01
12 Photograph of specimen of a Helminth / protozoa 01
13 Microscopic slide of ovum / egg ./ cyst 01
14 Photograph / Instrument / Report related to immunology 01
15 Examination of urine 01
16 Slide Coagulase Test 01
17 Catalase Test 01
18 Snear Preparation for staining 01
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16CURRICULUM IMC
MBBS SECOND PROFESSIONAL GENERAL PATHOLOGY AND MICROBIOLOGY
FORMATSr. No. COMMENTS MARKS
1 OSPE16 Stations (16 non-observed stations related to practicals (each of 04 marks) 64
2 Observed Practical Microbiology 16
3 STRUCTURED VIVA VOCE (related to curriculum 50
25+25(External + Internal)
4 ANNUAL WORK BOOK 05(External)
5 CONTINUOUS INTERNAL ASSESSMENT 15
Total 150
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17CURRICULUM IMC
SPECIAL PATHOLOGY
TABLE OF SPECIFICATION ( Theory)Sr. No. Topic Specification MCQ’s SEQ’s
1
Cardio-Vascular systemAneurysms of blood vesselsHeart failure Rheumatic heart Disease Ischemic Heart disease Pericardial disease tumors of heart or blood vesses
11111
1
2
HematologyRBC DiseasersWBC Disorders Bleeding and coagulation disorders
221
1
3
Respiratory systemDisease of vascular origin Chronic obstructive pulmonary diseasePulmonary InfectionsTumors
1112
1
4
Oral cavity and Gastro-intestinal TractOral Cavity Peptic UlcerCA Stomach AppendixEsophagesCA intestine Inflammatory Bowel diseasePancreatitis
21111111
2
5
Hepatobiliary systemInfectious DiseasesCirrhosisJaundice and cholesterol Hepatocellular CA
2111
1
6
Urinary system Glomerular Diseases Disease affecting tubules Tumors Urinary Bladder
2111
1
7Male genital systemTestiesProstate
23
1
8
Female genital systemCervixEndometrium Overy
122
1
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18CURRICULUM IMC
SPECIAL PATHOLOGY
TABLE OF SPECIFICATION ( Theory)Sr. No. Topic Specification MCQ’s SEQ’s
9Diseases of breastInflammationCarcinoma breast
14
1
10
EndocinologyPituitaryThyroid GlandAdrenal Gland
131
1
11
Musculo-Skeletal system and bones & jointsMuscular Dystrophy Disease of peripheral nerveArthritis Tumor of Bones
1111
1
12 Central Nervous systemTumors 2 1
13
Clinical chemistryDiabetic KetoacidosisCardiac Function TestsRenal Fubction tests
111
1
14 SkinTumors 1 1
Total 65 14
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19CURRICULUM IMC
MBBS THIRD PROFESSIONAL SPECIAL PATHOLOGY
FORMATSr. No. COMMENTS MARKS
1 OSPE20 Stations (Histopathology 10, Hematology 5, Chemical Pathology 5) 80
2 STRUCTURED VIVA VOCE (related to curriculum)50
25+25(External + Internal)
3 ANNUAL WORK BOOK 05(External)
4 CONTINUOUS INTERNAL ASSESSMENT 15
Total 150
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20CURRICULUM IMC
Con
tent
sO
bjec
tives
Do-
mai
nSt
rate
gyAs
sess
-m
ent
Mod
ule
1: In
flam
mat
ion,
Med
iato
rs o
f Infl
amm
atio
n
• Ro
le o
f infl
amm
atio
n in
the
defe
nse
mec
hani
sms
of th
e bo
dy.
• Va
scul
ar
chan
ges
of
acut
e in
flam
mat
ion
and
thei
r re
latio
n to
m
orph
olog
ical
and
tiss
ue e
ffect
s.•
Proc
ess
of C
hem
otax
is, O
pson
izat
ion
and
Phag
ocyt
osis
.•
Role
of c
ellu
lar
com
pone
nts
in in
flam
mat
ory
exud
ate.
• Ex
udat
es a
nd tr
ansu
date
.•
Impo
rtan
t che
mic
al m
edia
tors
of i
nflam
mat
ion.
• Pa
thw
ay o
f Ara
chid
onic
Aci
d m
etab
olis
m.
• Ro
le o
f pro
duct
s of
Ara
chid
onic
aci
d m
etab
olis
m in
infla
mm
atio
n.•
Mec
hani
sm fo
r de
velo
pmen
t of f
ever
, with
refe
renc
e to
exo
geno
us a
nd e
ndog
enou
s py
ro-
gens
.•
Chro
nic
infla
mm
atio
n in
clud
ing
Gra
nulo
mas
.•
Gra
nulo
ma
and
its ty
pes
alon
g w
ith c
ause
s.•
Syst
emic
effe
cts
of a
cute
and
chr
onic
infla
mm
atio
n an
d th
eir
poss
ible
out
com
es.
• Si
gnifi
canc
e of
ESR
.•
Indu
ced
hypo
ther
mia
in m
edic
ine.
• He
alin
g in
spe
cial
ized
tiss
ue.
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
Mod
ule
2: W
ound
Hea
ling
• Re
pair
and
rege
nera
tion.
• W
ound
hea
ling
by fi
rst a
nd s
econ
d in
tent
ion.
• Fa
ctor
s th
at in
fluen
ce th
e in
flam
mat
ory
repa
rativ
e re
spon
se.
• W
ound
con
trac
tion
and
cica
tris
atio
n.•
Form
atio
n of
gra
nula
tion
tissu
e.•
Com
plic
atio
ns o
f wou
nd h
ealin
g.
C3 C3 C3 C3 C3 C3
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
LEC/
SGD
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
SEQ
/MCQ
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21CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
3: D
isor
ders
of C
ircu
latio
n
a.
Thro
mbo
-em
bolic
dis
orde
rs a
nd th
eir
mod
aliti
es•
Etio
logy
and
pat
hoge
nesi
s of
thro
mbo
sis.
• Po
ssib
le c
onse
quen
ces
of th
rom
bosi
s•
Diffe
renc
e be
twee
n th
rom
bi a
nd c
lots
• Cl
assi
ficat
ion
of e
mbo
li ac
cord
ing
to th
eir
com
posi
tion.
• Di
ffere
nce
betw
een
arte
rial a
nd v
enou
s em
boli.
b.
Hem
orrh
age,
Hyp
erem
ia a
nd C
onge
stio
n•
Defin
ition
s of
com
mon
type
s of
Hem
orrh
age
• Ty
pes
of h
yper
emia
• Di
ffere
nce
betw
een
hype
rem
ia a
nd c
onge
stio
nc.
In
farc
tion
• Ty
pes
of in
farc
tion
• Di
ffere
nce
betw
een
anem
ic a
nd h
emor
rhag
ic in
farc
t•
Mor
phol
ogic
al p
ictu
re o
f inf
ract
ion
in d
iffer
ent o
rgan
sys
tem
sd.
D
isor
ders
of t
he c
ircu
latio
n an
d sh
ock
• Ed
ema,
asc
ites,
hyd
roth
orax
and
ana
sarc
a.•
Path
ophy
siol
ogy
of e
dem
a w
ith s
peci
al e
mph
asis
on
CHF.
• Pa
thog
enes
is o
f fo
ur m
ajor
typ
es o
f sh
ock
(Hyp
ovol
emic
, car
diog
enic
, vas
ovag
al &
se
ptic
) and
thei
r ca
uses
.•
Com
pens
ator
y m
echa
nism
s in
volv
ed in
sho
ck.
C2 C2 C3 C3 C3 C2 C2 C3 C3 C3 C3 C3 C3 C3 C3
Lect
ure
Lect
ure
Lect
ure
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
c
MCQ
/ S
EQM
CQ /
SEQ
MCQ
/ S
EQM
CQ /
SEQ
MCQ
/ S
EQ
MCQ
/ S
EQM
CQ /
SEQ
MCQ
/ S
EQ
MCQ
/ S
EQM
CQ /
SEQ
MCQ
/ S
EQ
MCQ
/ S
EQM
CQ /
SEQ
MCQ
/ S
EQ
MCQ
/ S
EQ
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22CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
4: M
icro
biol
ogy
• De
fenc
e m
echa
nism
s of
the
body
.•
Mic
robi
al m
echa
nism
s of
inva
sion
and
viru
lenc
e.•
Diffe
renc
e be
twee
n st
eriliz
atio
n an
d di
sinf
ectio
n.•
Met
hods
of d
isin
fect
ion
and
ster
ilizat
ion
of th
e fo
llow
ing:
a.
Faci
lity
whe
re th
e do
ctor
pra
ctic
es,
b.
Exam
inat
ion
tabl
e,c.
An
y sp
illage
e.g
. spu
tum
, vom
itus,
sto
ol, u
rine,
blo
od,
d.
Exam
inat
ion
tool
s, e
.g.,
ther
mom
eter
, nas
al a
nd e
ar s
pecu
la a
nd s
patu
la,
• Pr
inci
ples
of a
sept
ic t
echn
ique
s su
ch a
s Ve
nepu
nctu
re, u
rinar
y ca
thet
eriz
atio
n, b
anda
ging
, su
turin
g an
d lu
mbe
r pu
nctu
re.
• Un
iver
sal p
reca
utio
ns fo
r in
fect
ion
cont
rol.
• G
ener
al p
rinci
ples
of t
he fo
llow
ing
sero
logi
cal t
ests
:a.
EL
ISA
– He
patit
is (A
,B,C
,D,E
,G) R
ubel
la, C
MV
and
HIV
b.
PCR
c.
Haem
aggl
utin
atio
n –
TPHA
d.
Wes
tern
Blo
t –HI
V M
alar
ia.
8.
Inte
rpre
tatio
n of
:a.
Cu
lture
repo
rts
b.
Sero
logi
cal r
epor
ts a
ndc.
M
icro
scop
ic re
port
s of
gra
m s
tain
and
ZN
sta
in.
• Pr
inci
ples
of p
rope
r co
llect
ion
and
subm
issi
on o
f spe
cim
ens
for
labo
rato
ry in
vest
igat
ions
• G
ener
al c
hara
cter
istic
s an
d ta
xono
my
of B
acte
ria, R
icke
ttsia
, Chl
amyd
ia, V
iruse
s an
d Fu
ngi.
• Co
mm
unic
able
, End
emic
, Epi
dem
ic, a
nd P
ande
mic
Dis
ease
s, C
arrie
rs P
atho
gens
, Opp
ortu
n-is
ts, C
omm
ensa
ls a
nd C
olon
izer
s.
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
MCQ
/ S
EQM
CQ /
SEQ
MCQ
/ S
EQM
CQ /
SEQ
MCQ
/ S
EQ
MCQ
/ S
EQM
CQ /
SEQ
MCQ
/ S
EQM
CQ /
SEQ
MCQ
/ S
EQ
ww
w.im
c.ed
u.pk
23CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
4: M
icro
biol
ogy
• C
omm
on o
rgan
ism
s ca
usin
g C
NS
Infe
ctio
ns(i)
Ba
cter
ia: S
tept
ococ
cus
pneu
mon
iae,
Bet
a he
mol
ytic
us s
rtep
toco
ccus
gro
up-b
, Nei
sser
ia
men
ingi
tides
, Hae
mop
hilis
influ
enza
e M
ycob
acte
rium
tube
rcul
osis
. E.c
oli,
List
eria
mon
ocy-
toge
nes
(ii)
Viru
ses:
Ent
erov
irus,
Mum
ps H
erpe
s Ad
enov
irus
(iii)
Fung
us: C
rypt
ococ
cus
neof
orm
is(iv
) Pr
otoz
oa M
alar
ia T
oxop
lasm
a•
Com
mon
org
anis
ms
caus
ing
resp
irat
ory
trac
t inf
ectio
n(i)
Ba
cter
ia: S
tept
ococ
cus
pneu
mon
iae,
Bet
a he
mol
ytic
us s
trept
ococ
cus
grou
p b
Dipt
heria
sp
., Bo
rdet
ella
sp.
Hem
ophi
lus
influ
enza
e, M
ycob
acte
riurn
tube
rcul
osis
Kle
bsie
lla, L
egio
nel-
la, M
ycop
lasm
a pn
eum
onia
e(ii
) Vi
ruse
s: H
erpe
s A
deno
viru
s M
easl
es In
fluen
za P
ara
influ
enza
Rhi
novi
rus
RSV
(iii)
Prot
ozoa
: Pne
umoc
ystic
car
inii
• O
rgan
ism
s ca
usin
g ga
stro
inte
stin
al tr
act i
nfec
tion
/ in
fest
atio
n(i)
Ba
cter
ia: C
lost
ridiu
m d
iffici
le M
ycob
acte
rium
tube
rcul
osis
Sal
mon
ella
, Shi
gella
Vib
rio c
hol-
era,
Vib
rio p
arah
emol
ytic
us C
ampy
loba
cter
jeju
ni H
elic
obac
ter
pylo
ri(ii
) Vi
ruse
s: H
epat
itis
A Ro
ta, A
stro
(iii)
Fung
us: C
rypt
ococ
cus
neof
orm
is(v
i) P
roto
zoa:
Gia
rdia
lam
blia
Ent
ameb
a hi
stol
ytic
a Cr
ypto
spor
idiu
m•
Com
mon
org
anis
ms
caus
ing
hepa
tic in
fect
ions
(i)
Bact
eria
: Stre
ptoc
occu
s sp
ecie
s, C
olifo
rms,
Ana
erob
es(ii
) Vi
ruse
s: H
erpe
s, H
epat
itis
A, B
, C, D
, E C
MV,
EBV
(iii)
Prot
ozoa
: Ent
ameb
a hi
stol
ytic
a, T
ape
wor
ms,
Ech
inoc
occu
s gr
anul
osus
• C
omm
on o
rgan
ism
s ca
usin
g sk
in in
fect
ion
(i)
Bact
eria
: Sta
phyl
ococ
cus
aure
us, S
trept
ococ
cus
pyog
enes
, Act
inom
yces
isra
elli,
Noc
ardi
a as
tero
ides
, Myc
obac
teriu
m tu
berc
ulos
is, M
ycob
acte
rium
lepr
ae, C
oryn
ebac
teriu
m d
ipht
he-
riae
(ii)
Viru
ses:
Her
pes,
Mea
sles
Rub
ella
, Chi
cken
pox
, Mol
uscu
m c
onta
gios
um(ii
i) Fu
ngus
: Can
dida
alb
ican
s, T
inea
spe
cies
(iv)
Arth
ropo
des:
Sar
copt
es s
cabi
ei, P
edic
ulus
spe
cies
, Cin
ex le
ctul
ariu
s(v
) He
lmin
ths:
Fila
ria s
peci
es, S
trong
yloi
des
ster
cora
lis, S
chis
toso
ma
sp.
(vi)
Prot
ozoa
: Lei
shm
ania
spe
cies
.
C3 C3 C3 C2 C2
SGD
/ Le
c
SGD
/ Le
c
SGD
/ Le
c
SGD
/ Le
c
SGD
/ Le
c
MCQ
/ S
EQ
MCQ
/ S
EQ
MCQ
/ S
EQ
MCQ
/ S
EQ
MCQ
/ S
EQ
ww
w.im
c.ed
u.pk
24CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
4: M
icro
biol
ogy
• C
omm
on o
rgan
ism
s ca
usin
g bo
ne a
nd jo
int i
nfec
tion
• Ba
cter
ia:
Stap
h au
reus
, St
rept
ococ
cus
pyog
enes
, Ha
emop
hilu
s in
fluen
zae,
Nei
sser
ia g
on-
orrh
oeae
, Bru
cella
mel
itene
sis,
Sal
mon
ella
typh
i, St
rep.
pne
umon
ae, P
seud
omon
as s
p. a
nd
Myc
obac
teriu
m tu
berc
ulos
is.
• C
omm
on o
rgan
ism
s ca
usin
g ge
nita
l inf
ectio
n(i)
Ba
cter
ia: M
ycop
lasm
a ur
ealy
ticum
(ii)
Viru
ses:
Pox
, Her
pes,
Hep
atiti
s B,
HIV
(iii)
Fung
us: C
andi
da a
lbic
ans
(iv)
Arth
ropo
des:
Sar
copt
es s
cabi
ei(v
) Pr
otoz
oa: T
ricom
onas
vag
inal
is•
Com
mon
org
anis
ms
caus
ing
zoon
osis
(i)
Viru
ses:
Rab
ies,
(ii)
Prot
ozoa
: Tox
opla
sma
gond
ii, L
eish
man
ia s
p.(ii
i) He
lmen
thic
s: E
chin
ococ
cus
sp.
C3 C3 C3
SGD
/ Le
c
SGD
/ Le
c
SGD
/ Le
c
MCQ
/ S
EQ
MCQ
/ S
EQ
MCQ
/ S
EQ
Mod
ule
5: P
rinc
iple
s of
ant
i-mic
robi
al a
ctio
n.
• An
tibio
tics,
sel
ectiv
e to
xici
ty, b
acte
riost
atic
and
bac
teric
idal
.•
Host
det
erm
inan
ts in
rela
tion
to s
elec
tion
of a
n an
timic
robi
al d
rug
for
ther
apy.
• M
inim
um i
nhib
itory
con
cent
ratio
n (M
IC)
and
min
imum
bac
teric
idal
con
cent
ratio
n (M
BC)
• Ba
cter
ial r
esis
tanc
e an
d th
e m
echa
nism
s in
volv
ed in
acq
uirin
g ba
cter
ial r
esis
tanc
e•
Mec
hani
sms
invo
lved
in
tran
sfer
of
drug
res
ista
nce
to b
acte
rial r
esis
tanc
e.•
Mod
e of
act
ion
of v
ario
us a
ntim
icro
bial
dru
g gr
oups
.•
Supe
rinfe
ctio
n an
d cr
oss
sens
itivi
ty
C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
25CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
6: G
enet
ics
• Co
mm
on s
ex li
nked
, aut
osom
al re
cess
ive
and
auto
som
al d
omin
ant d
isor
ders
.•
Com
mon
gen
etic
mut
atio
ns.
• Di
seas
es a
ssoc
iate
d w
ith c
onsa
ngui
neou
s m
arria
ges.
• M
olec
ular
bio
logy
tech
niqu
es.
C3 C3 C3 C3
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
Mod
ule
7: G
row
th D
isor
ders
/Neo
plas
ia
• At
roph
y an
d Hy
pert
roph
y, A
gene
sis,
Dys
gens
is,
Apla
sia,
Hyp
opla
sia,
Hyp
erpl
asia
, M
etap
la-
sia,
Dys
plas
ia, N
eopl
asia
, Ana
plas
ia,.
• Ce
ll cy
cle
and
cell
type
s (s
tabl
e, la
bile
, per
man
ent)
• M
echa
nism
s co
ntro
lling
cell
grow
th•
Clas
sific
atio
n sy
stem
s of
tum
ors.
• Ch
arac
teris
tics
of b
enig
n an
d m
alig
nant
tum
ors
• Di
ffere
nce
betw
een
Carc
inom
a an
d Sa
rcom
a.•
Gra
ding
and
sta
ging
sys
tem
of t
umor
s.•
Biol
ogy
of tu
mor
gro
wth
• Pr
oces
s of
car
cino
gene
sis
• Ho
st d
efen
se a
gain
st tu
mor
s.•
Mec
hani
sm o
f loc
al a
nd d
ista
nt s
prea
d.•
Loca
l and
sys
tem
ic e
ffect
s of
tum
ors.
• Tu
mor
mar
kers
use
d in
the
diag
nosi
s an
d m
anag
emen
t of c
ance
rs.
• Co
mm
on c
hem
ical
, phy
sica
l age
nts
and
viru
ses
rela
ted
to h
uman
can
cer.
• Ep
idem
iolo
gy o
f com
mon
can
cers
in P
akis
tan.
• Ra
diat
ion
and
its e
ffect
s on
tiss
ues.
• Ca
ncer
scr
eeni
ng.
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
26CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
8: Im
mun
olog
y
• An
tigen
, ant
ibod
y, e
pito
pe, h
apte
n an
d ad
hesi
on m
olec
ules
.•
Diffe
renc
e be
twee
n in
nate
and
acq
uire
d im
mun
ity.
• St
ruct
ure
and
func
tion
of m
ajor
his
toco
mpa
tibilit
y co
mpl
ex (M
HC).
• Cy
toki
nes.
• M
echa
nism
of h
umor
al a
nd c
ell m
edic
ated
imm
unity
.•
Hype
rsen
sitiv
ity re
actio
ns, T
ype
I, Ty
pe II
, Typ
e III
and
Type
IV.
• Au
togr
aft,
hom
ogra
ft, a
llogr
aft a
nd x
enog
raft.
• Im
mun
otol
eran
ce a
nd im
mun
opar
alys
is.
• M
echa
nism
invo
lved
in a
llogr
aft r
ejec
tion
and
step
s th
at c
an b
e ta
ken
to c
omba
t rej
ectio
n.•
Clas
sific
atio
n of
Imm
unod
efici
ency
dis
orde
rs•
Basi
s of
aut
oim
mun
ity.
• Ti
ssue
tran
spla
ntat
ion.
• Pa
thol
ogy
and
path
ogen
esis
of A
IDS.
• La
b di
agno
sis
of im
mun
olog
ical
dis
ease
s.
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD/
LAB
SGD/
LAB
SGD/
LAB
SGD/
LAB
SGD/
LAB
SGD/
LAB
SGD/
LAB
SGD/
LAB
SGD/
LAB
SGD/
LAB
SGD/
LAB
SGD/
LAB
SGD/
LAB
SGD/
LAB
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
27CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
9: B
LOO
D V
ESSE
LS &
HEA
RT
• At
hero
scle
rosi
sEt
iolo
gy a
nd p
atho
gene
sis,
Ear
ly le
sion
, Lat
e an
d co
mpl
icat
ed le
sion
, Ves
sels
affe
cted
, Co
mpl
icat
ions
• M
onke
berg
’s m
edia
l cal
cific
scl
eros
is•
Arte
riolo
scle
rosi
s.•
Hype
rten
sion
Clas
sific
atio
n, C
ause
s of
sec
onda
ry h
yper
tens
ion,
Vas
cula
r ch
ange
s in
hyp
erte
nsio
n.•
Com
mon
pat
hoge
netic
mec
hani
sms
of v
ascu
litis
.•
Aneu
rysm
Clas
sific
atio
n, E
tiolo
gy.
• At
hero
scle
rotic
ane
urys
mPa
thog
enes
is, T
ype
of v
esse
l inv
olve
d, M
orph
olog
ical
& c
linic
al fe
atur
es•
Varic
ose
vein
sCo
mm
on s
ites,
Pre
disp
osin
g fa
ctor
s, C
linic
al fe
atur
es.
• Be
nign
and
mal
igna
nt tu
mou
rs o
f blo
od v
esse
ls.
• Pa
thog
enes
is o
f isc
hem
ic h
eart
dis
ease
.•
Myo
card
ial i
nfar
ctio
nSe
quen
ce o
f cha
nges
in m
yoca
rdia
l inf
arct
ion
(M.I)
, Pat
tern
of e
leva
tion
of b
ioch
emic
al m
ark-
ers
used
in th
e ev
alua
tion
of M
.I, C
ompl
icat
ions
.•
Caus
es o
f sud
den
card
iac
deat
h.•
Cor-p
ulm
onal
e•
Pred
ispo
sing
dis
orde
rs.
• Rh
eum
atic
End
ocar
ditis
• Ba
cter
ial E
ndoc
ardi
tis•
Etio
logy
, Pat
hoge
nesi
s, M
orph
olog
ical
& c
linic
al fe
atur
es, C
ompl
icat
ions
• M
yoca
rditi
s.•
Mor
phol
ogic
al a
nd c
linic
al fe
atur
es o
f myo
card
itis.
• Ca
rdio
myo
path
yDi
late
d, H
yper
troph
ic, R
estr
ictiv
e.•
Peric
ardi
tis.
• Cl
inic
al a
nd m
orph
olog
ical
feat
ure
of p
eric
ardi
tis.
• Pr
imar
y &
seco
ndar
y ca
rdia
c tu
mou
rs.
• Fa
llot’s
tetr
alog
y•
Coar
ctat
ion
of a
orta
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
28CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
10: H
EMAT
OPO
IETI
C A
ND
LY
MPH
OID
SY
STEM
S
• St
ages
in th
e fo
rmat
ion
of re
d bl
ood
cell
and
whi
te b
lood
cel
ls.
• N
orm
al v
alue
s of
red
cel
l cou
nt, H
emog
lobi
n le
vel,
Pack
ed c
ell v
olum
e, M
CH, M
CV, M
CHC,
W
BC C
ount
, Pla
tele
t cou
nt,
• An
emia
Cla
ssifi
catio
n, C
ause
s, E
tiolo
gy,
Bloo
d pi
ctur
e, c
linic
al f
eatu
res
and
Lab
Diag
nosi
s of
,Iro
n de
ficie
ncy
anem
ia, M
egal
obla
stic
ane
mia
, Fol
ate
defic
ienc
y an
emia
, Vit.
B12
defi
cien
cy
anem
ia, A
nem
ia o
f chr
onic
dis
ease
, Nut
ritio
nal d
efici
ency
ane
mia
.•
Here
dita
ry s
pher
ocyt
osis
, Inc
iden
ce, E
tiolo
gy, P
atho
gene
sis,
Mor
phol
ogic
al a
nd C
linic
al fe
a-tu
res
• Th
alas
sem
ia, C
lass
ifica
tion,
Pat
hoge
nesi
s, B
lood
pic
ture
, Clin
ical
and
gen
etic
feat
ures
.•
Hem
olyt
ic a
nem
ia•
Glu
cose
-6-p
hosp
hate
deh
yrog
enas
e de
ficie
ncy.
• Im
mun
ohem
olyt
ic a
nem
ia.
• W
arm
and
col
d an
tibod
ies
imm
unoh
emol
ytic
ane
mia
s.•
Apla
stic
ane
mia
, Etio
logy
, Pat
hoge
nesi
s, C
linic
al fe
atur
es, L
ab. D
iagn
osis
.•
Neu
trope
nia
• Ag
ranu
locy
tosi
s•
Leuk
ocyt
osis
• In
fect
ious
mon
onuc
leos
is, E
pide
mio
logy
, Mor
phol
ogy,
Clin
ical
feat
ures
.•
Acut
e an
d ch
roni
c no
nspe
cific
lym
phad
eniti
s.•
Non
-hod
gkin
’s ly
mph
oma,
Cla
ssifi
catio
n (re
al a
nd w
orki
ng fo
rmul
atio
ns)
• Ho
dgki
n’s
dise
ase,
Cla
ssifi
catio
n, C
linic
al s
tage
s, E
tiolo
gy a
nd p
atho
gene
sis
• Le
ukem
ia•
Prog
nost
ic fa
ctor
s of
acu
te ly
mph
obla
stic
and
acu
te m
yelo
blas
tic le
ukem
ias.
• Pa
thop
hysi
olog
y of
chr
onic
mye
loid
and
chr
onic
lym
phoc
ytic
leuk
emia
s•
Mul
tiple
mye
lom
a, E
tiolo
gy, P
atho
gene
sis,
Mor
phol
ogy,
Clin
ical
feat
ures
• Di
ssem
inat
ed in
trav
ascu
lar
coag
ulat
ion,
Etio
logy
, Pat
hoge
nesi
s, C
linic
al fe
atur
es, L
abor
ato-
ry d
iagn
osis
• Ca
uses
of d
ecre
ased
pro
duct
ion
and
decr
ease
d su
rviv
al o
f pla
tele
ts.
• Id
iopa
thic
& th
rom
botic
thro
mbo
cyto
peni
c pu
rpur
a•
Valu
e of
follo
win
g te
sts
in th
e as
sess
men
t of b
leed
ing
diso
rder
sBl
eedi
ng t
ime,
Clo
tting
tim
e, P
late
lets
cou
nt,
Plat
elet
fun
ctio
n te
st,
Part
ial t
hrom
bopl
astin
tim
e, P
roth
rom
bin
time,
Mix
ing
test
stu
dies
• Po
lycy
them
ia, E
tiolo
gy, P
atho
gene
sis,
Clin
ical
sig
nific
ance
, Lab
. Dia
gnos
is•
ABO
and
Rhe
sus
bloo
d gr
oups
• Sc
reen
ing
of D
onor
s•
Haza
rds
of b
lood
tran
sfus
ion
and
thei
r pr
even
tion.
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
29CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
11: R
ESPI
RAT
ORY
SY
STEM
• M
icro
-org
anis
ms
caus
ing
uppe
r re
spira
tory
trac
t inf
ectio
n.•
Etio
logy
and
clin
ical
feat
ures
of;
Rhin
itis,
Nas
al p
olyp
s, A
cute
pha
ryng
itis,
Acu
te t
onsi
llitis
, Ac
ute
bact
eria
l epi
glot
tis,
Acut
e la
ryng
itis,
Ple
ural
effu
sion
, Hem
otho
rax,
Hyd
roth
orax
, Ple
uriti
s, P
neum
otho
rax,
Chy
loth
orax
• M
alig
nant
& b
enig
n tu
mou
rs o
f nas
opha
rynx
and
lary
nx.
• At
elec
tasi
s,
Clas
sific
atio
n, P
atho
gene
sis
• Re
stric
tive
& ob
stru
ctiv
e lu
ng d
isea
se•
Etio
logy
pat
hoge
nesi
s, m
orph
olog
y &
clin
ical
feat
ures
of;
Asth
ma,
Var
ious
type
s of
em
phys
ema,
Chr
onic
bro
nchi
tis, B
ronc
hiec
tasi
s, A
dult
resp
irato
ry
dist
ress
syn
drom
e, R
estr
ictiv
e lu
ng d
isea
ses,
Sar
coid
osis
, Hyp
erse
nsiti
vity
pne
umon
itis,
Id-
iopa
thic
pul
mon
ary
fibro
sis,
Goo
dpas
ture
’s s
yndr
ome,
Thr
ombo
embo
li, P
ulm
onar
y in
farc
tion,
Pu
lmon
ary
hype
rten
sion
and
vas
cula
r sc
lero
sis.
• Ac
ute
bact
eria
l pne
umon
ia.
• M
icro
-org
anis
ms
caus
ing
atyp
ical
pne
umon
ia.
• Et
iolo
gy, p
atho
gene
sis
& cl
inic
al fe
atur
es o
f;Tu
berc
ulos
is o
f the
lung
, Pne
umoc
onio
sis
• Fu
ngi (
cand
ida,
pne
umoc
ystis
car
inii)
cau
sing
lung
infe
ctio
ns.
• Br
onch
ogen
ic c
arci
nom
a an
d m
esot
helio
ma
Clas
sific
atio
n, E
tiolo
gy, P
atho
gene
sis,
Clin
ical
feat
ures
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
30CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
12: T
HE
OR
AL C
AVIT
Y A
ND
GAS
TRO
INTE
STIN
AL T
RAC
T
• O
ral c
avity
Leuk
opla
kia,
Ora
l can
cer,
Risk
fact
ors,
Mor
phol
ogy,
Clin
ical
feat
ure.
• Be
nign
and
mal
igna
nt tu
mou
rs o
f sal
ivar
y gl
ands
.•
Pleo
mor
phic
ade
nom
a, C
linic
al fe
atur
es, M
orph
olog
y•
Esop
hagu
sPr
edis
posi
ng fa
ctor
s of
eso
phag
itis,
Car
cino
ma
of th
e es
opha
gus
• St
omac
h,
Etio
logy
, pat
hoge
nesi
s, m
orph
olog
ical
and
clin
ical
feat
ures
of ;
• Ac
ute
gast
ritis
Chro
nic
gast
ritis
, Pep
tic u
lcer
, Gas
tric
car
cino
ma,
Ris
k fa
ctor
s, P
atho
gene
sis,
Mor
phol
ogy
• Cl
inic
al fe
atur
es a
nd d
iagn
osis
, Pro
gnos
is.
• In
test
ine
Etio
logy
, pat
hoge
nesi
s, m
orph
olog
ical
and
clin
ical
feat
ures
of,
Hirs
chsp
rung
’s d
isea
se, C
eli-
ac s
prue
, Tro
pica
l spr
ue, I
sche
mic
bow
el d
isea
se, C
rohn
’s d
isea
se, U
lcer
ativ
e co
litis
.•
Acut
e ap
pend
iciti
s•
Maj
or c
ause
s of
inte
stin
al o
bstr
uctio
n.•
Clin
ico-
path
olog
ical
feat
ures
of f
ollo
win
g di
seas
es o
f int
estin
eAm
ebia
sis,
Tub
ercu
losi
s, T
ypho
id•
Non
-neo
plas
tic p
olyp
s of
inte
stin
e.•
Aden
omas
Clas
sific
atio
n on
the
basi
s of
epi
thel
ial a
rchi
tect
ure,
Clin
ical
and
mor
phol
ogic
al fe
atur
es•
Colo
rect
al c
arci
nom
a•
Clas
sific
atio
n, E
tiolo
gy, P
atho
gene
sis,
Mor
phol
ogic
al a
nd c
linic
al fe
atur
es, A
ster
-Col
ler
clas
-si
ficat
ions
of c
arci
nom
a of
the
colo
n an
d re
ctum
, •
Carc
inoi
d tu
mou
r•
Peak
inci
denc
e, M
ost p
reva
lent
site
s in
the
gut,
Mor
phol
ogic
al fe
atur
es, C
linic
al fe
atur
es o
f ca
rcin
oid
synd
rom
e.•
Etio
logy
, pat
hoge
nesi
s, m
orph
olog
ical
and
clin
ical
feat
ures
of t
umou
rs o
f app
endi
x.•
Live
r an
d Bi
liary
Tra
ctLi
ver,
Path
way
of b
ilirub
in m
etab
olis
m a
nd it
s el
imin
atio
n fro
m th
e bo
dy, J
aund
ice,
Cla
ssifi
ca-
tion,
Cau
ses,
Clin
ical
feat
ures
, Lab
dia
gnos
is, I
ntra
hepa
tic a
nd e
xtra
hepa
tic b
iliary
obs
truc
-tio
n.
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
c
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
31CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
12: T
HE
OR
AL C
AVIT
Y A
ND
GAS
TRO
INTE
STIN
AL T
RAC
T
• Et
iolo
gy, p
atho
gene
sis,
mor
phol
ogy,
clin
ical
feat
ures
and
com
plic
atio
n of
;He
patic
failu
re, C
irrho
sis,
•
Vira
l hep
atiti
s A,
B,C,
D an
d E
• Ro
ute
of tr
ansm
issi
on, I
ncub
atio
n pe
riod,
Clin
ical
feat
ures
.•
Pote
ntia
l out
com
e of
acu
te in
fect
ion.
• Ca
rrie
r st
ate,
Acu
te a
nd c
hron
ic h
epat
itis.
• Et
iolo
gy, m
orph
olog
ical
and
clin
ical
feat
ures
of l
iver
abs
cess
.•
Drug
s an
d to
xins
cau
sing
hep
atic
inju
ry•
Path
ogen
esis
of a
lcoh
ol li
ver
dise
ase.
• M
orph
olog
ical
and
clin
ical
feat
ures
of a
lcoh
olic
hep
atiti
s an
d ci
rrho
sis.
• Cl
assi
ficat
ion,
etio
logy
, pat
hoge
nesi
s, m
orph
olog
ical
and
clin
ical
feat
ures
of;
Hem
ochr
omat
osis
, Sec
onda
ry h
emoc
hrom
atos
is, W
ilson
’s d
isea
se, A
lpha
-1 a
ntitr
ypsi
n de
fi-ci
ency
, Neo
nata
l hep
atiti
s, P
rimar
y an
d se
cond
ary
bilia
ry c
irrho
sis,
Hep
atoc
ellu
lar c
arci
nom
a•
Bilia
ry tr
act
Epid
emio
logy
, Pat
hoge
nesi
s, M
orph
olog
y, C
linic
al fe
atur
es,
• Pa
thog
enes
is a
nd r
isk
fact
ors
of c
hole
lithi
asis
.•
Mor
phol
ogic
al a
nd c
linic
al fe
atur
es o
f acu
te a
nd c
hron
ic c
hole
cyst
itis.
• Cl
inic
al a
nd m
orph
olog
ical
feat
ures
of g
all b
ladd
er c
ance
r.Pa
ncre
as, A
cute
and
chr
onic
pan
crea
titis
, Etio
logy
, Pat
hoge
nesi
s, M
orph
olog
y, C
linic
al fe
a-tu
res.
• Cl
inic
al a
nd m
orph
olog
ical
feat
ures
of c
arci
nom
a of
pan
crea
s.
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
c
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
32CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
13: T
HE
UR
INAR
Y S
YST
EM
• Et
iolo
gy, p
atho
gene
sis,
clin
ical
feat
ures
and
com
plic
atio
ns o
f;Az
otem
ia,
Urem
ia,
Acut
e re
nal f
ailu
re,
Chro
nic
rena
l fai
lure
, Po
lycy
stic
kid
ney
dise
ase
(its
Clas
sific
atio
n),
Glo
mer
ulon
ephr
itis
(its
Clas
sific
atio
n),
Nep
hrot
ic a
nd n
ephr
itic
synd
rom
e,
Acut
e py
elon
ephr
itis,
Chr
onic
pye
lone
phrit
is, H
ydro
neph
rosi
s.•
Path
ogen
esis
and
clin
ical
cou
rse
of a
cute
tubu
lar
necr
osis
.•
Beni
gn a
nd m
alig
nant
nep
hros
cler
osis
• Ch
arac
teris
tics
of v
ario
us ty
pes
of re
nal s
tone
s•
Path
ogen
esis
, clin
ical
feat
ures
and
lab
diag
nosi
s of
nep
hrol
ithia
sis
• Ep
idem
iolo
gy, m
orph
olog
y, c
linic
al fe
atur
es a
nd p
rogn
osis
of W
ilm’s
tum
our
• Cl
assi
ficat
ion,
Epi
dem
iolo
gy,
mor
phol
ogy,
clin
ical
fea
ture
s an
d pr
ogno
sis
of r
enal
cel
l car
-ci
nom
a•
Etio
logy
, mor
phol
ogy
& cl
inic
al fe
atur
es o
f cys
titis
.•
Clin
ical
feat
ures
, etio
logy
and
mor
phol
ogy
of tr
ansi
tiona
l cel
l car
cino
ma
of th
e ur
inar
y bl
ad-
der.
C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
Mod
ule
14: M
ALE
GEN
ITAL
SY
STEM
• Hy
posp
adia
s•
Unde
scen
ded
test
is•
Uret
hriti
s (G
onoc
occa
l, N
on g
onoc
occa
l)Et
iolo
gy, R
oute
of i
nfec
tion,
Pat
hoge
nesi
s, D
iagn
osis
• Et
iolo
gy, p
atho
gene
sis
and
natu
ral h
isto
ry o
f;Pr
osta
titis
, Pro
stat
ic h
yper
plas
ia.
• Ca
uses
, pat
hoge
nesi
s an
d cl
inic
al fe
atur
es o
f scr
otal
sw
ellin
g.Te
stic
ular
adn
exa,
Var
icoc
ele,
Hyd
roce
le, S
perm
atoc
ele,
Tes
tis a
nd e
pidi
dym
is, I
nflam
mat
ion
(Orc
hitis
), Ep
idid
ymiti
s.•
Caus
es, p
atho
gene
sis
and
rele
vant
inve
stig
atio
ns o
f mal
e in
ferit
lity.
• Cl
assi
ficat
ion,
pat
hoge
nesi
s, m
orph
olog
y, c
linic
al fe
atur
es a
nd p
rogn
osis
of t
he tu
mou
rs o
f th
e m
ale
geni
tal t
ract
(Pro
stat
e,Te
stis
)
ww
w.im
c.ed
u.pk
33CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
15: F
EMAL
E G
ENIT
AL S
YST
EM
• Ca
uses
, rou
tes
of in
fect
ion
& m
etho
ds o
f dia
gnos
is o
f sex
ually
tran
smitt
ed d
isea
ses.
• Ro
ute
of in
fect
ion,
pat
hoge
nesi
s an
d La
b di
agno
sis
of;
Gon
orrh
ea, S
yphi
lis, C
hlam
ydia
, HPV
, Her
pes
sim
plex
, Tric
hom
onas
vag
inal
is.
• Ce
rvic
al in
trae
pith
elia
l neo
plas
ia•
Neo
plas
ms
of c
ervi
x•
Caus
es,
path
ogen
esis
and
clin
ical
fea
ture
s of
dys
func
tiona
l ute
rine
blee
ding
with
spe
cial
re
fere
nce
to e
ndom
etria
l hyp
erpl
asia
,end
omet
rial p
olyp
and
car
cino
ma.
• Et
iolo
gy, c
linic
al fe
atur
es a
nd p
atho
gene
sis
of;
Aden
omyo
sis,
End
omet
riosi
s, E
ctop
ic p
regn
ancy
, Tox
emia
of p
regn
ancy
.•
Clas
sific
atio
n, p
atho
gene
sis,
mor
phol
ogy,
clin
ical
feat
ures
and
pro
gnos
is o
f the
tum
ours
of
the
fem
ale
geni
tal t
ract
(ute
rus,
ova
ry a
nd G
esta
tiona
l tro
phob
last
ic tu
mou
rs).
C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
c
SGD
/ Le
c
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
Mod
ule
16: B
REA
ST
• Et
iolo
gy a
nd c
ause
s of
lum
p in
the
brea
st•
Etio
logy
, Pat
hoge
nesi
s, M
orph
olog
y an
d cl
inic
al fe
atur
es;
Mas
titis
, Fib
rocy
stic
dis
ease
of t
he b
reas
t, In
trad
ucta
l pap
illom
a•
Beni
gn tu
mou
rs o
f the
bre
ast (
Fibr
oade
nom
a an
d Ph
yllo
des
tum
our)
• G
ynae
com
astia
• Ca
rcin
omas
of t
he b
reas
t (Du
ctal
and
Lob
ular
)
C3 C3 C3 C3 C3
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
34CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
17: M
USC
ULO
SKEL
ETAL
SY
STEM
• Pa
thog
enes
is a
nd c
linic
al fe
atur
es o
f ;Ac
hond
ropl
asia
, Ost
eoge
nesi
s im
perf
ecta
, Ost
eopo
rosi
s.•
Acut
e an
d ch
roni
c os
teom
yelit
isCo
mm
on c
ausa
tive
mic
ro-o
rgan
ism
, Com
mon
rout
es o
f spr
ead,
Com
plic
atio
ns.
• Co
mm
on s
ites
invo
lved
in tu
berc
ulou
s os
teom
yelit
is•
Path
ogen
esis
, mor
phol
ogic
al a
nd c
linic
al fe
atur
es o
f Pag
et’s
dise
ase
(ost
eitis
def
orm
ans)
.•
Beni
gn a
nd m
alig
nant
bon
e fo
rmin
g tu
mou
rs.
• Co
mm
on s
ites,
mor
phol
ogic
al a
nd c
linic
al fe
atur
es o
f ost
eoge
nic
sarc
oma.
• Be
nign
and
mal
igna
nt c
artil
agin
ous
tum
ours
.•
Chon
dros
arco
ma
Peak
inci
denc
e, C
omm
on s
ites
of o
rigin
, Mor
phol
ogic
al a
nd c
linic
al fe
atur
es.
• M
ost f
requ
ent s
ites,
clin
ical
and
mor
phol
ogic
al fe
atur
es o
f gia
nt c
ell t
umou
rs o
f bon
e.•
Ewin
g’s
sarc
oma
Peak
inci
denc
e, C
omm
on s
ites
of o
rigin
, Chr
omos
omal
abn
orm
ality
, Mor
phol
ogic
al a
nd c
lin-
ical
feat
ures
.•
Path
ogen
esis
, mor
phol
ogic
al a
nd c
linic
al fe
atur
es o
f ost
eoar
thrit
is•
Rheu
mat
oid
arth
ritis
Path
ogen
esis
, Mor
phol
ogic
al a
nd c
linic
al fe
atur
es, L
ab D
iagn
osis
• G
out.
Clas
sific
atio
n, P
atho
gene
sis,
Mor
phol
ogic
al a
nd c
linic
al fe
atur
es, L
ab D
iagn
osis
• Pa
thog
enes
is, m
orph
olog
ical
and
clin
ical
feat
ures
of;
Duch
enne
mus
cula
r dy
stro
phy,
Myo
toni
c dy
stro
phy,
Con
geni
tal m
yopa
thie
s, In
flam
mat
ory
myo
path
ies,
Mya
sthe
nia
grav
is.
• Li
pom
a an
d lip
asar
com
a.•
Rhab
dom
yosa
rcom
aPe
ak in
cide
nce,
His
tolo
gica
l var
iant
s, F
requ
ent s
ites
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
c
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
35CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
18: E
ND
OC
RIN
E SY
STEM
• Pi
tuita
ry,
Caus
es o
f hy
perp
ituita
rism
, M
orph
olog
y an
d cl
inic
al f
eatu
res
of,
Pitu
itary
ade
no-
mas
, Acr
omeg
aly,
Gig
antis
m.
• Ca
uses
of h
ypop
ituita
rism
, Etio
logy
, pat
hoge
nesi
s an
d cl
inic
al fe
atur
es o
f, Sh
eeha
n’s
synd
rom
e, D
war
fism
, Etio
logy
, clin
ical
feat
ures
, pat
hoge
nesi
s an
d la
b fin
ding
s in
in
appr
opria
te s
ecre
tion
of A
DH.
• Ad
rena
l Cor
tex
and
Med
ulla
• Ad
rena
l cor
tical
hyp
erfu
nctio
n. (C
USHN
G’S
SYN
DRO
ME)
, Etio
logy
, pat
hoge
nesi
s cl
inic
al fe
a-tu
res
and
lab
diag
nosi
s of
;•
Conn
’s sy
ndro
me,
Adr
enog
enita
l syn
drom
e, C
ause
s of
hyp
ofun
ctio
n of
adr
enal
cor
tex.
• Et
iolo
gy, p
atho
gene
sis
and
clin
ical
feat
ures
of A
ddis
on’s
dise
ase.
• Tu
mou
rs o
f adr
enal
med
ulla
and
cor
tex.
• Cl
inic
al fe
atur
es a
nd d
iagn
osis
of p
heoc
hrom
ocyt
oma.
• Th
yroi
d•
Etio
logy
and
clin
ical
feat
ures
of h
yper
thyr
oidi
sm.
• Et
iolo
gy a
nd c
linic
al fe
atur
es o
f hyp
othy
roid
ism
incl
udin
g Cr
etin
ism
and
Myx
edem
a.•
Inve
stig
atio
n /
lab
test
s fo
r di
agno
sis
of th
yroi
d dy
sfun
ctio
n.•
Goi
ter
and
its ty
pes
• Et
iolo
gy, p
atho
gene
sis
and
clin
ical
feat
ures
of d
iffus
e an
d m
ultin
odul
ar g
oite
r.•
Caus
es o
f sol
itary
thyr
oid
nodu
le a
nd it
s di
agno
stic
app
roac
h.•
Thyr
oidi
tisTy
pes,
Pat
hoge
nesi
s, M
orph
olog
y, C
linic
al fe
atur
es•
Etio
logy
, pat
hoge
nesi
s, m
orph
olog
y an
d cl
inic
al fe
atur
es o
f;Fo
llicul
ar a
deno
ma,
Pap
illary
car
cino
ma,
Fol
licul
ar c
arci
nom
a, M
edul
lary
car
cino
ma,
Und
if-fe
rent
iate
d.•
Type
s of
MEN
syn
drom
es.
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
c
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
c
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
36CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
18: E
ND
OC
RIN
E SY
STEM
• Pa
rath
yroi
d•
Etio
logy
and
clin
ical
feat
ures
of h
yper
para
thyr
oidi
sm a
nd h
ypop
arat
hyro
idis
m.
• Pr
imar
y, s
econ
dary
and
tert
iary
hyp
erpa
rath
yroi
dism
.•
Calc
ium
hom
eost
asis
• Ca
uses
of h
yper
and
hyp
ocal
cem
ia.
• SK
IN,
Mac
ule,
pap
ule,
nod
ule,
pla
que,
ves
icle
, bu
lla,
blis
ter,
puts
ule,
sca
le,li
chen
ifica
tion,
ex
coria
tion,
hyp
erke
rato
sis,
par
aker
atos
is,
acan
thos
is,d
yske
rato
sis,
aca
ntho
lysi
s, p
apillo
-m
atos
is, l
entig
inou
s sp
ongi
osis
.•
Mor
phol
ogic
al a
nd c
linic
al fe
atur
es o
f urt
icar
ia.
• Et
iolo
gy, p
atho
gene
sis
mor
phol
ogic
al a
nd c
linic
al fe
atur
es o
f;Ec
zem
atou
s de
rmat
itis,
Con
tact
der
mat
itis,
Ato
pic
derm
atiti
s, P
hoto
ecze
mat
us e
rupt
ions
, Pr
imar
y irr
itant
der
mat
itis,
Ery
them
a m
ultif
orm
e, P
soria
sis,
Pem
phig
us, B
ullo
us p
emph
igoi
d.•
Prem
alig
nant
epi
thel
ial l
esio
ns.
• Ty
pes
of w
arts
and
thei
r m
ost f
requ
ent l
ocat
ions
.•
Pred
ispo
sing
fact
ors,
mor
phol
ogy,
clin
ical
feat
ures
and
pro
gnos
is o
f;•
Squa
mou
s ce
ll ca
rcin
oma,
Bas
al c
ell c
arci
nom
a.•
Type
s, c
linic
al a
nd m
orph
olog
ical
feat
ures
of;
Nev
ocel
lula
r N
evi,
Dysp
last
ic n
evi.
• M
alig
nant
mel
anom
aCl
assi
ficat
ion,
Fre
quen
t site
of o
rigin
, Clin
ical
and
mor
phol
ogic
al fe
atur
es.
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
c
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
37CURRICULUM IMC
Con
tent
sO
bjec
tives
Dom
ain
Stra
tegy
Asse
ss-
men
t
Mod
ule
19: N
ERVO
US
SYST
EM
• Cl
inic
o-pa
thol
ogic
al fe
atur
es o
f hyd
roce
phal
us.
• Ce
rebr
al e
dem
a (v
asog
enic
& c
ytot
oxic
).•
Type
s of
her
niat
ion
of b
rain
and
thei
r cl
inic
al s
igni
fican
ce.
• In
tra-
cran
ial h
emor
rhag
e.•
Etio
logi
c ag
ents
, clin
ical
and
mor
phol
ogic
al fe
atur
es o
f;Ac
ute
puru
lent
men
ingi
tis, A
cute
lym
phoc
ytic
men
ingi
tis, C
hron
ic m
enin
gitis
, Bra
in a
bsce
ssTu
berc
ulos
is m
enin
gitis
, Vira
l enc
epha
litis
• Cl
inic
o-pa
thol
ogic
al fe
atur
es o
f Gui
llain
Bar
re s
yndr
ome.
• Po
lyne
urop
athi
es•
Toxi
c ne
urop
athy
• Im
port
ant
intr
acra
nial
tum
ours
(as
trocy
tom
a,ol
igod
endr
oglio
mas
, ep
endy
mom
a, m
edul
lo-
blas
tom
a an
d m
enin
giom
a)•
Clin
ical
sig
nific
ance
of g
lial t
umou
rs.
• Fr
eque
nt m
etas
tatic
tum
ours
to th
e br
ain
• Pr
imar
y pe
riphe
ral n
erve
she
ath
neop
lasm
s
C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3 C3
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
cSG
D /
Lec
SGD
/ Le
c
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
MCQ
/SEQ
ww
w.im
c.ed
u.pk
38CURRICULUM IMC
Domain Level
Knowledge
C1 Knowledge C2 Comprehension C3 ApplicationC4 AnalysisC5 SynthesisC6 Evaluation
Psychomotor
P1 Observe P2 Practice P3 Adjust P4 MasterP5 DevelopP6 Construct
Affect
A1 ReceivingA2 RespondingA3 ValuingA4 OrganizationA5 Characterization
