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CURRICULUM VITAE
Name, title : Edy Meiyanto, Dr. Apt. M.Sc., Professor
Place, Date of Birth : Solo, Mei 2nd 1962
Address : Arwana Street No. 12, Rt/Rw 031/005, Perum Minomartani,
Ngaglik, Sleman, Daerah Istimewa Yogyakarta
Email Address : [email protected]; [email protected];
[email protected]; [email protected]
Research Gate :
https://www.researchgate.net/researcher/54386761_E_Meiyanto
Google Scholar :
http://scholar.google.com/citations?user=C1DwiokAAAAJ&hl=en
EDUCATION
No Degree University Completion Year
1 Bachelor Gadjah Mada University 1986
2 Master Gadjah Mada University 1995
3 Doctoral NARA Institute of Science and Technology
(NAIST), Japan
2001
4 Professional Gadjah Mada University 1987
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PRESENT OCCUPATION
1. Chairman of Cancer Chemoprevention Research Center (CCRC), Faculty of Pharmacy,
Universitas Gadjah Mada (http://ccrc.farmasi.ugm.ac.id)
2. Reviewer of Indonesian Journal of Pharmacy (accredited)
(http://mfi.farmasi.ugm.ac.id)
3. Chairman of Indonesian Society for Cancer Chemoprevention (ISCC) (http://iscc-
indonesia.org)
ACADEMIC POSSITION
1990 – 1993 Junior assistant
1995 - 1997 Senior assistant
2001 – 2007 Lecturer
2007 – 2010 Associate professor
2010 – now Professor
TEACHING ACTIVITIES
1. Research Methodology (S-1 and S-2)
2. Molecular Biology (S-1, S-2, and S-3)
3. Biochemistry (S-1)
4. Karsinogenesis molecular (S-2 and S-3)
5. Analysis Clinic/biomedik (S-1 and S-2)
RESEARCH INTEREST
No Title Funding Resource
Year
1 Molecular Target Analysis of 8-Hidroxyisokapnolakton-2',3'-Diol with Cisplatin on Nfkb and Cox-2 and Those Affectivity on cell cycle of colon cancer
Research Grant IMHERE
Faculty of Pharmacy UGM
2012
2 Development of Specific Molecular-Targeted Agents to Increase Sensitivity of resistance Breast Cancer Cells to Chemoterapeutic Agent
Research Grant for
International Collaboration
DIKTI
2012-2014
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3 Production of Protein Farmasetik Recombinant Human Erythropoietin (rhepo) with Modification Pattern Glikosilasi on the Hek293T
RISTEK-SINAS Research
Cooperation with LIPI
2012-2014
4 Potensi dan Molecular Targets Senyawa Aktif Ekstrak Etanolik Kayu Secang (Caesalpinia sappan L) sebagai Agen Chemosensitizer pada Kanker Payudara : Pengembangan Fitofarmaka Secang Sebagai Agen Kemopreventif Komplementer untuk Terapi Kanker Payudara yang Lebih Efektif (Kolaborasi antara Cancer Chemoprevention Research Center dengan Balai Besar Penelitian dan Pengembangan Tanaman Obat dan Obat Tradisional).
Grant Cooperation Institutions
2013
5 Design Based Formula Cancer Drugs Herbs Combination Directed by Approach to Breast Cancer Metastatic
Insentif SiNAS Ristek
2014
6 Development Technologi and application Boron Neutron Capture Cancer Therapy with Compact Neutron Generator
Insentif SiNAS Ristek
(Konsorsium with BATAN)
2014-2016
7 Validation methode of genotoxic assay for natural product and food additives
PUPT DIKTI 2015-2016
8 Measure Effect Bifasik Genistein, Curcumin and Analog to be Developed as a an Anticancer Estrogenik and of Preparations
HIKOM DIKTI 2016
9 Pengembangan Teknologi dan Aplikasi Boron Neutron Capture Cancer Therapy dengan Compact Neutron Generator : Mengembangkan Senyawa Boron Berbasis Analog Kurkumin dan Sistem Ujinya
RISTEK DIKTI 2016
10 Pengembangan Produksi Bahan Baku Obat Berbasis Biosimilar Recombinant Human Erythropoietin : Uji Aktivitas Biologi In Vitro dan In Vivo serta Uji Toksisitas Akut Produk Biosimilar Recombinant Human Erythropoietin
RISTEK DIKTI 2016
11 Menakar Efek Bifasik Genistein, Kurkumin dan Analognya untuk Dikembangkan sebagai Agen Antikanker dan Sediaan Estrogenik
Hibah Kompetensi
(Tahun Kedua)
2017
12 Manufaktur dan Standardisasi Komponen Kolimator dan Obat Berbasis Boron Neutron Capture Cancer Therapy (BNCT)
Program Insentif Inovasi Industri (PIII)
Kerjasama dengan BATAN
2017
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13 Pengembangan Produksi Bahan Baku Obat Berbasis
Biosimiliar Recombinant Human Erythropoietin
Sub Judul: Uji Aktivitas Biologi In Vivo serta Uji Toksisitas Akut Produk Biosimilar Recombinant Human Erythropoietin
PPTI Kerjasama
dengan Biofarma dan LIPI (Tahun
Kedua)
2017
14 Pengembangan Metode Analisis Reactive Oxygen
Spesies (Ros) Menggunakan 2’,7’-
Dichlorofluorescin Diacetate (Dcfda) pada MCF-
7/HER2 dan NIH3T3
Hibah Pengembangan
Penelitian Laboratorium dengan Lab.
Kimia Analisis DKF
2017
15 Efek Kombinasi Hesperetin dengan Doksorubisin
terhadap Proliferasi dan Metastasis pada Sel
Kanker 4T1
Hibah Penelitian Penunjang
Thesis
2017
16 Pengembangan Agen Anti Kanker Payudara dari
Daun Katuk Hutan Papua: Kajian Efek Anti
Proliferatik dan Anti Metastatik
Hibah Pekerti 2017
17 Isolasi Senyawa Aktif dari Daun Micromelum
minutum dan Penelusuran Aktivitas Penghambatan
pada Sel Kanker Payudara MCF-7
PUPT 2017
CURRENT RESEARCH ACTIVITIES
I established a research center in the faculty of Pharmacy, UGM, namely Cancer
Chemoprevention Research Center (CCRC) (http://ccrc.farmasi.ugm.ac.id) focusing on the
development of agents (synthetic and natural origin) to indentify, prevent, inhibit,
modulate, and reverse of developing cancer and/or cell proliferation and differentiation.
CCRC has plenty collaborative researches with other institutions (universities and other
research groups) and funding resources from industries and government. CCRC research
activities are particularly in cancer chemoprevention focuses on in vitro, in vivo, and in
silico experiments. The in vitro researches included observing cytotoxicity of Indonesian
plant’s extract, metabolites and curcumin analogues in several cancer cell lines, such as
breast cancer cell line (T47D; MCF-7), cervical cancer cell line (HeLa), and colon cancer cell
line (WiDr), either single or in combination with chemotherapeutical agents. Besides
cytotoxicity, CCRC also investigates the chemopreventive, antiproliferative, and apoptosis
effect of agents using double staining, immunohistochemistry, AgNOR staining, FACS
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analyses, as well as gene expression studies to establish a targeted therapy of cancer. CCRC
also use RAW 264.7 macrophage cell line as the model of cell differentiation and
immunomodulatory studies. CCRC also works in vivo i.e. studying chemopreventive effect
in rat induced by dimethyl benzo(a)anthracene (DMBA) as well as implant cell method;
investigating immunostimulatory effect in rat treated by cytostatic agent, and estrogenic
activity using ovariectomized rat. Recently CCRC is developing in silico studies covering
bioinformatics research to explore drug-receptor interaction using MOE and PLANT
programs.
ACHIEVEMENTS
No Awards Received Given By Date/Venue 1 JP Patent 2004147501: Method for
Detecting DNA with High Sensivity JP Patent 2004147501 2004
2 Silver medal as Supervisor in PIMNAS (PKMI category)
Rector of Universitas Gadjah Mada (UGM)
2006
3 1st winner of Ristek – MITC (research category)
Ministry of Higher Education of Republic Indonesia
2007
4 Best supervisor of UGM students reasoning
Rector of Universitas Gadjah Mada (UGM)
2007
5 Best supervisor of student research Rector of Universitas Gadjah Mada (UGM)
2011
6 Best research and best presenter in DIKTI Research Seminar
Indonesian Ministry of Education and Culture
2014
7 The honors of Satyalancana Karya Satya The President of Indonesia 2014 8 Outstanding Lecturer Dean of Faculty of
Pharmacy Universitas Gadjah Mada
2007, 2011, 2014
9 1st winner Best Research Category of Ristek Kalbe Science Award
Indonesian Ministry of Research and Technology
2014
10 Patent of Pentagamaboronon-0 (PGB-0) Kementerian Hukum dan Hak Asasi Manusia RI (Direktorat Jenderal Hak Kekayaan Intelektual)
2015
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PROFESIONAL ORGANIZATION
Positions Professional Organizations Year Member of Council Experts
Indonesian Pharmacists Association 2014 – up to now
President Indonesian Society for Cancer Chemoprevention
2010 – up to now
President Cancer Chemoprevention Research Center (CCRC), Faculty of Pharmacy UGM
2004 – up to now
Faculty Advisor International Society for Pharmaceutical Engineering (ISPE) DIY-Jateng Student Chapter
2013-2015
Central board Indonesian Natural Medicine Research Society
2009
Member Indonesian Biochemistry and Molecular Biology Society
Up to now
Member International Society for Pharmaceutical Engineering (ISPE)
Up to now
Member Japan Cancer Association Up to now Member Asia Pacific Organization of Cancer
Prevention Up to now
Member Organization of Oncology and Translational Research
Up to know
Member Yogyakarta Pharmacist Association Up to now Advisory board Indonesian Pharmacist Association 2004 - 2008 Advisory board Indonesian Pharmacist Association 2009 - 2013 Advisory Board Indonesian Pharmacist Association 2014 – up to now
RECORDS OF INTERNATIONAL ACTIVITY
1. Oral presentation at The Asia Pacific Organization on Cancer Prevention (APOCP)
Conference, Nagoya, Japan, 2002
2. Visiting Scientist at Nara institute of Science and Technonogy, Japan, October 2002
3. Visiting Scientist at Nara institute of Science and Technonogy, Japan, October 2004
4. Oral presentation at the international seminar on Cancer diagnostic and theraphy,
Yogyakarta-Indonesia, 2005
5. Oral presentation at the 21st congress of Federation of Asian Pharmaceutical
Associations, Yokohama-Japan, 2006
6. Oral presentation at the international symposium on recent progress in curcumin
research, Yogyakarta-Indonesia-2006
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7. Oral presentation at the international seminar on the Henk Timmerman : Structure
based Drug Development, LIPI-Indonesia, 2007
8. Oral presentation at the international seminar on Application of molecular biology on
drug discovery and medical diagnosis, Nov 28th 2008 Faculty of Pharmacy
Muhammadiyah University of Surakarta, Indonesia
9. Oral presentation at the International seminar on Drug discovery, March 16-18, 2009,
Makassar
10. Poster presentation at the International Kyoto Breast Cancer Consensus Conference,
Kyoto-Japan, 16-18 April 2009
11. Oral Presentation at the Conference of AASP-MPSPS Penang Malaysia, June 11-13, 2009
12. Oral presentation at the International Conference of Chemoprevention for health and
beauty, ISCC, Yogyakarta Oct 9, 2010
13. Speaker at the APPS, Yogyakarta, July 4, 2011
14. Speaker at the International seminar Natural Product for Cancer Chemoprevention,
UMP, Purwokerto, July 5, 2011
15. Presenter at OOTR the 8th Annual Conference, OOTR, Japan, April 20-22, 2012
16. Moderator and Committee at In the International Conference Research and Application,
UMS, Surakarta, June 22-23,2012
17. Presenter at The 5th Indonesia Biotechnology Conference an International Forum “
Green Industrial Innovation Through Biotechnology”, Konsorsium Bioteknologi
Indonesia, Mataram July 4th-7th, 2012
18. Speaker at The 3rd International Conference on Pharmacy and Advanced
Pharmaceutical Science, Fakultas Farmasi UGM, Yogyakarta, June 18-19, 2013
19. Presenter at 72nd Annual Meeting of The Japanese Cancer Association, JCA, Japan,
October 3-5, 2013
20. Presenter at 73rd Annual Meeting of The Japanese Cancer Association, JCA,
Japan,September 25-27, 2014.
21. Speaker at MICAPS (Medan International Conference on Advance Pharmaceutical
Science) : Advanced Drug Development in Cancer Chemoprevention and Metabolic
Disorders, Medan, Sumatera Utara, November 6-7th, 2014.
22. Speaker at PICAPS (Pontianak International Conference on Advance Pharmaceutical
Science), Pontianak, Kalimantan Barat, September 14-15th, 2015
23. Presenter at 74th Annual Meeting of The Japanese Cancer Association, JCA, Japan,
October 08-10th, 2015
24. Speaker at International Symposium on the Application of Nuclear Technology to
Support National Sustainable Development: Health, Agriculture, Energy, Industry, and
Environment, Satya Wacana Christian University, Indonesia, October 26-28, 2015.
25. Oral Presentation at 75nd Annual Meeting of The Japanese Cancer Association, JCA,
Japan, October 6-8, 2016.
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26. Speaker at WHICAPS (Wahid Hasyim International Conference on Advanced
Pharmaceutical Science), Semarang, November 7-8th, 2016.
27. Poster Presentation at 76th Annual Meeting of The Japanese Cancer Association, JCA,
Japan, September 28-30, 2017
28. Oral Presentation at The 2nd International Conference on Medicinal Chemistry,
Bandung, October 5-6, 2017
29. Invited Speaker at The 2nd Universitas Muhammadiyah Purwokerto Pharmacy
International Conference and 8th Indonesian Society of Cancer Chemoprevention,
Purwokerto, October 13-14, 2017
PUBLICATIONS
2012
1. Nurulita, N.A.,Meiyanto, E., Sugiyanto, Matsuda, E., and Kawaichi, M., 2012, Gynura
procumbens Modulates the Microtubules Integrity and Enhances Distinct Mechanism
on Doxorubicin and 5-Fluorouracil-induced Breast Cancer Cell Death, Orient. Pharm.
Exp. Med., Volume: 12 Issue: 3 (2012-09) Page: 205-218 DOI 10.1007/s13596-012-
0063-5. Published online: 23 Feb 2012.
2. Sugiyanto, B. Sudarto, Meiyanto, E., Nugroho, A.E.,and Jenie, U.A., 2003, The
Anticarcinogenic Activity of Plants Compounds, MFI, 14 (4): 216-225.
3. Fithriyatun Nisa, Adam Hermawan, Retno Murwanti, Edy Meiyanto, 2012,
Antiproliferative effect of gynura procumbens (lour.) Merr. Leaves etanolic extract on
7,12-dimethylbenz(a)antracene induced male rat liver, Advanced Pharmaceutical
Bulletin, 2(1), 99-106.
4. Endang Purwaningsih, Sri Kadarsih Soejono, Djaswadi Dasuki and Edy Meiyanto, 2012,
Curcumin inhibits luteal cell steroidogenesis by suppression of extracellular signal
regulated kinase. Universa Medicina, 31(2): 73-80
5. Agung Endro N, Adam Hermawan, Dyaningtyas Dewi PP., Edy Meiyanto, Lukman
Hakim., 2012. Synergistic effect of ethyl acetate fraction on Ficus septica Burm.f. and
doxorubicin chemotherapy on T47D human breast cancer cell line. Journal of Chinese
Integrative Medicine , Vol. 10 No. 10: 1162-1170.
6. Sri Handayani, Chandra Risdian, Edy Meiyanto, Zalinar Udin, Rina Andriyani, and
Marissa Angelina., 2012., Selaginella Active Fractions Induce Apoptosis on T47D Breast
Cancer Cell., Indonesian Journal of Pharmacy., Volume 23 Issue 1 : 48-53.
7. Agung Endro Nugroho, Adam Hermawan, Kunti Nastiti, Suven, Pritha Elisa, Tony
Hadibarata, Edy Meiyanto. Immunomodulatory Effects of Hexane Insoluble Fraction of
Ficus septica Burm. F. in Doxorubicin-treated Rats. Asian Pacific Journal of Cancer
Prevention, 2012 : Vol 13 (11) : 5785-5790.
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8. Agung Endro Nugroho, Adam Hermawan, Dyaningtyas Dewi Pamungkas Putri and Edy
Meiyanto, 2012, Combination Effects of Hexane Insoluble Fraction of Ficus septica
Burm. F. and Doxorubicin Chemotherapy on T47D Breast Cancer Cell Lines, Asian
Pacific Journal of Tropical Biomedicine, 3(4):297-302.
9. Nurulita, N.A.,Meiyanto, E., Sugiyanto, Matsuda, E., and Kawaichi, M., 2012, Gynura
procumbens Prevents Chemoresistance through Inhibition MDR1 Expression on MCF-7
Breast Cancer Cell Line and Sensitizes the Cells to Doxorubicin, Indonesian Journal of
Biotechnology, Vol. 17, No. 1, pp.51-60.
10. Adam Hermawan, Kholid Alfan Nur, Sarmoko, Dyaningtyas Dewi, Pamungkas Putri, Edy
Meiyanto. Ethanolic extract of Moringa oleifera increased
cytotoxic effect of doxorubicin on HeLa cancer cells. Journal of Nature Remedies. Vol.
12/2 (2012)108-114.
2013
1. Agung Endro Nugroho, Adam Hermawan, Dyaningtyas Dewi Pamungkas Putri, Anindya
Novika, Edy Meiyanto. Combinational effects of hexane insoluble fraction of Ficus
septica Burm. F. and doxorubicin chemotherapy on T47D breast cancer cells. Asian Pac J
Trop Biomed 2013; 3(4): 297-302.
2. Sri Handayani, Adam Hermawan, Edy Meiyanto, Zalinar Udin. Induction of Apoptosis
on MCF-7 cells by Selaginella Fractions. Journal of Applied Pharmaceutical Science Vol.
3 (04), pp. 031-034, April, 2013.
3. Muhammad Da’i, Arry Yanuar, Edy Meiyanto,Umar Anggara Jeniec and Amir Margono
Supardjan.(2E,5E)-2,5-Bis(4-hydroxy-3-methoxybenzylidene)cyclopentanone ethanol
monosolvate. Acta Cryst. (2013). E69, o530.
4. Ari Widiyantoro, Thamrin Usman, Edy Meiyanto, Sabirin Matsjeh. Cytotoxic Activity of
Crude Extracts and Fractions from Irvingia malayana. IOSR Journal Of Pharmacy.
Volume 3, Issue 4 (May 2013), Pp 05-08.
2014
1. Meiyanto E, Putri DD, Susidarti RA, Murwanti R, Sardjiman, Fitriasari A, Husnaa U,
Purnomo H, Kawaichi M. Curcumin and its Analogues (PGV-0 and PGV-1) Enhance
Sensitivity of Resistant MCF-7 Cells to Doxorubicin through Inhibition of HER2 and NF-
kB Activation. Asian Pac J Cancer Prev. 2014. 15(1):179-84.
2. Rifki Febriansah, Dyaningtyas Dewi Pamungkas Putri, Sarmoko, Nunuk Aries Nurulita,
Edy Meiyanto, Agung Endro Nugroho. Hesperidin as a preventive resistance agent in
MCF-7 breast cancer cells line resistance to doxorubicin. Asian Pac J Trop Biomed 2014;
4(3): 228-233.
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3. Anugerah Budipratama Adina, Fina Aryani Goenadi, Franciscus Feby Handoko, Dwi Ana
Nawangsari, Adam Hermawan, Riris Istighfari Jenie and Edy Meiyanto. Combination of
Ethanolic Extract of Citrus aurantifolia Peels with Doxorubicin Modulate Cell Cycle and
Increase Apoptosis Induction on MCF-7 Cells. Iranian Journal of Pharmaceutical
Research (2014), 13 (3): 919-926.
4. Adam Hermawan, Anugerah Budipratama Adina, Fina Aryani Goenadi, Fransiscus Feby
Handoko, Dwi Ana Nawangsari, Riris Istighfari Jenie, and Edy Meiyanto. Combination
of Ethanolic Extract of Citrus aurantifolia Peels with Doxorubicin Modulate Cell Cycle
and Increase Apoptosis Induction on MCF-7 Cells. Iranian Journal of Pharmaceutical
Research. 2014.
5. Ratna Asmah Susidarti, Riris Istighfari Jenie, Muthi Ikawati, Dyaningtyas Dewi
Pamungkas Putri, Edy Meiyanto. Cytotoxic activity and apoptosis induction of 8-
hydroxyisocapnolactone-2´,3´-diol and its combination with Doxorubicin on MCF-7 and
T47D cells. J App Pharm Sci, 2014; 4 (06):089-097.
6. Sarmoko, Dyaningtyas Dewi Pamungkas Putri, Ratna Asmah Susidarti, Agung Endro
Nugroho, Edy Meiyanto. Increasing Sensitivity Of Mcf-7/Dox Cells Towards
Doxorubicin By Hesperetin Through Suppression Of P-Glycoprotein Expression.
Indonesian J. Pharm. Vol. 25 No. 2 : 84 – 90.
7. Yonika Arum Larasati, Dyaningtyas Dewi Pamungkas Putri, Rohmad Yudi Utomo, Adam
Hermawan, Edy Meiyanto. Combination of Cisplatin and Cinnamon Essential Oil
Inhibits HeLa Cells Proliferation through Cell Cycle Arrest. J App Pharm Sci. 2014; 4(12):
014-019.
8. Edy Meiyanto, Herwandhani Putri, Yonika Arum Larasati, Ria Fajarwati.
Pengembangan Boron Carrying Pharmaceuticals untuk Mendukung Terapi Kanker
Berbasis BNCT. Prosiding Pertemuan dan Presentasi Ilmiah-Penelitian Dasar Ilmu
Pengetahuan dan Teknologi Nuklir PSTA Batan. 2014: 156-162.
2015
1. N.P. Linda Laksmiani, R. Asmah Susidarti, Edy Meiyanto. Brazilein Increases the
Sensitivity of Doxorubicin on MCF-7 Resistant Doxorubicin (MCF-7/DOX) Cells Through
Inhibition of HER-2 Activation. International Journal of Pharmacy and Pharmaceutical
Sciences. 2015. Vol 7, Issue 2, 525-528.
2. Adam Hermawan, Retno Murwanti, Nina Artanti, Edy Meiyanto. Effect of the Water
Extract of Macrosolen Cochinchinensis (Lour.) Tiegh. Leaves on 7, 12-dimethylbenz [a]
antracene induced female mice liver carcinogensis. 2015. Journal of Chinese
Pharmaceutical Sciences. 20 (2011) 627-632.
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3. Ni Putu Linda Laksmiani, Ratna Asmah Susidarti, Edy Meiyanto. Brazilein Increased
Cytotoxic Activity of Doxorubicin on MCF-7/DOX Cells. Indonesian Journal of Cancer
Chemoprevention. 2015. 6(2): 58-63.
4. Astrid Ayu Maruti, Fikri Amalia, Edy Meiyanto. Synergistic Effect of Arecoline in
Combination with Doxorubicin on HeLa Cervical Cancer Cells. Indonesian Journal of
Cancer Chemoprevention. 2015. 6(2): 64-70.
5. Prisnu Tirtanirmala, Annisa Novarina, Rohmad Yudi Utomo, Raisatun Nisa Sugiyanto,
Riris Istighfari Jenie, Edy Meiyanto, 2015, Cytotoxic and Apoptotic-inducing Effect of
Fraction Containing Brazilein from Caesalpinia sappan L. and Cisplatin on T47D Cell
Lines, Indonesian Journal of Cancer Chemoprevention, Vol. 6, No.3, p:89-96.
2016
1. Ika Rahmawati Sutejo, Herwandhani Putri, Edy Meiyanto. The Selectivity of Ethanolic
Extract of Buah Makassar (Brucea javanica) on Metastatic Breast Cancer Cells. 2016.
Journal of Agromedicine and Medical Sciences. Vol 2, Issue 1, 1-6.
2. Herwandhani Putri, Riris Istighfari Jenie, Ria Fajarwati Kastian, Edy Meiyanto.
Combination of Potassium Pentagamavunon-0 and Doxorubicin Induces Apoptosis and
Cell Cycle Arrest and Inhibits metastasis in Breast Cancer Cells. Asian Pac J Cancer Prev.
2016. 17(5), 2683-8.
3. Rul Afiyah Syarif, Sri Kadarsih Soejono, Edy Meiyanto, Mae Sri H Wahyuningsih. Effects
of Curcumin on Estrogen Secretion and Estrogen Receptor β in Pig Granulosa Cells of
Medium Follicles. 2016. Jurnal Kedokteran Brawijaya. Vol 29, No.1 : 32-38.
4. Sari Haryanti, Suwijiyo Pramono, Retno Murwanti, Edy Meiyanto. The Synergistic Effect of
Doxorubicin and Ethanolic Extract of Caesalpinia sappan L. Wood and Ficus septica Burm.f.
Leaves on Viability, Cell Cycle Progression, And Apoptosis Induction of MCF7 Cells. Indonesian
Journal of Biotechnology. Vol 21, No.1 : 29-37.
5. Sri Handayani, Ratna Asmah Susidarti, Zalinar Udin, Edy Meiyanto, Riris Istighfari Jenie.
Brazilein in Combination with Cisplatin Inhibit Proliferation and Migration on Highly Metastatic
cancer Cells, 4T1. 2016. Indonesian Journal of Biotechnology. Vol 21, No. 1: 38-47.
2017
1. Sri Handayani, Ratna Asmah Susidarti, Riris Istighfari Jenie, Edy Meiyanto. Two Active
Compunds from Caesalpinia sappan L. in Combination with Cisplatin Synergistically
Induce Apoptosis and Cell Cycle Arrest on Widr Cell. 2017. Advanced Pharmaceutical
Bulletin. Vol 7, No. 3: 375-380.
2. Sari Haryanti, Retno Murwanti, Herwandhani Putri, Gagas Pradani Nur Ilmawati,
Suwijiyo Pramono, Edy Meiyanto. Different 4T1 Cells Migration under Caesalpinia
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sappan L. and Ficus septica Burm.f Ethanolic Extracts. 2017. Indonesian Journal of
Cancer Chemoprevention. Vol 8, No. 1: 21-26.
3. Riris Istighfari Jenie, Sri Handayani, Ratna Asmah Susidarti, Zalinar Udin, Edy
Meiyanto. Cytotoxic and Antimetastasis Effect of Ethyl Acetate Fraction from
Caesalpinia sappan L. on MCF-7/HER2 Cells. 2017. Indonesian Journal of Cancer
Chemoprevention. Vol. 8, No. 1: 42-50.
4. Rohmad Yudi Utomo, Herwandhani Putri, Pudjono, Ratna Asmah Susidarti, Riris
Istighfari Jenie, Edy Meiyanto. Synthesis and Cytotoxic Activity of 2,5-Bis(4-Boronic
Acid)Benzylidine Cyclopentanone on HER2 Overexpressed-Cancer Cell. 2017.
Indonesian Journal of Pharmacy. Vol 28 No 2: 74-81.
5. Ulfatul Husnaa, Ni Putu Linda Laksmiani, Ratna Asmah Susidarti, Edy Meiyanto. Ethyl
Acetate Fraction of Caesalpinia sappan L. Enhances Cisplatin’s Cytotoxicity on HeLa
Cells via G1 and S Arrest through p53 Expression. 2017. Indonesian Journal of Cancer
Chemoprevention. Vol 8, No. 2: 51-60.
6. Nur Dina Amalina, Ika Putri Nurhayati, Edy Meiyanto. Doxorubicin Induces
Lamellipodia Formation and Cell Migration. 2017. Indonesian Journal of Cancer
Chemoprevention. Vol 8, No. 2: 61-67.
7. Beni Lestari, Dhania Novitasari, Herwandhani Putri, Sari Haryanti, Ediati Sasmito, Edy
Meiyanto. Evaluation of The Genotoxicity of Three Food Additives using CHO-K1 Cells
under in vitro Micronucleus Flow Cytometry Assay. 2017. Indonesian Journal of Cancer
Chemoprevention. Vol 8, No. 2: 74-80.
8. Nur Fitra Sari, Beni Lestari, Dian Saputri, Anisa Fauzia Ahsani, Ragil Anang Santoso,
Ediati Sasmito, Edy Meiyanto. Reveal Cytotoxicity and Antigenotoxicity of Piper nigrum
L. Ethanolic Extract and its Combination with Doxorubicin on CHO-K1 Cells. 2017.
Indonesian Journal of Cancer Chemoprevention. Vol. 8, No. 3: 110-119.
9. Devi Nisa Hidayati, Riris Istighfari Jenie, Edy Meiyanto. Combination of Curcuma
(Curcuma xanthorriza Roxb) hizome Ethanolic Extract and Awar-awar (Ficus septica
Burm. F) Leaves Ethanolic Extract Increases Cisplatin Cytotoxicity on T47D Breast
Cancer Cells through Cell Cycle Modulation. 2017. Indonesian Journal of Cancer
Chemoprevention. Vol. 8, No. 3: 120-125.
10. Asri Mega Putri, Nindya Budiana Putri, Rahmawaty Rachmady, Idlohatud Dilalah, Retno
Murwanti, Edy Meiyanto. Secang Heartwood Ethanolic Extract (Caesalpinia sappan L.)
Inhibits Mesenchymal Stem Cells Senescene. 2017. Indonesian Journal of cancer
Chemoprevention. Vol. 8, No. 3: 126-134.
11. Yoce Aprianto, Asri Mega Pratiwi, Hilyatul Fadliyah, Retno Murwanti, Edy Meiyanto.
Abtigenotoxic Activity of Rumput Mutiara (Hedyotis corymbosa L.) Ethanolic Extract on
Cyclophosphamide-Induced Mice. 2017. Indonesian Journal of Cancer
Chemoprevention. Vol. 8, No. 3: 135-145.
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2018
1. Edy Meiyanto, Endah Puji Septisetyani, Yonika Arum Larasati, Masashi Kawaichi.
Curcumin Analog Pentagamavunon-1 (PGV-1) Sensitizes Widr Cells to 5-Flurouracil
through Inhibition of NF-kB Activation. 2018. Asian Pacific Journal of Cancer
Prevention. Vol. 19, No. 1: 49-56.
2. Yonika Arum Larasati, Noriko Yoneda-Kato, Ikuko Nakamae, Takashi Yokoyama, Edy
Meiyanto, Jun-ya Kato. Curcumin Targets Multiple Enzymes Involved in the ROS
Metabolic Pathway to Seppress Tumor Cell Growth. 2018. Scientific Reports 8: 2039.
PATENT
MEIYANTO EDY, ISHIDA NORIHIRO, TAKEYA TATSUO, MINENO JUNICHI, ASADA KIYOZOU,
and KATO IKUNOSHIN, 2004, JP Patent 2004147501: METHOD FOR DETECTING DNA
WITH HIGH SENSITIVITY, published in: 2004-05-27
EXPERIENCES OF THE OTHER
1. As Vice Chairman Editorial Majalah Farmasi Indonesia (Accredited B)
2. As Constructor of Reasoning Students UGM (2007-2011)
3. As reviewer of Bahan Alam Indonesia Journal (Accredited B)
4. As National Reviewer of Creativity Student Program (PKM) (2009-now)
5. As Reviewer Grant research Internal of Faculty and University
6. As Reviewer Indonesian Journal of Cancer Chemoprevention (2010-now)
Yogyakarta, Februari 2018
Prof. Dr. Edy Meiyanto, M.Si., Apt. NIP. 19620502 198903 1 006
