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1 CURRICULUM VITAE NAME : Choo Keng Ee TELEPHONE 609 7190125 EMAIL/FAX : [email protected] DATE OF BIRTH : 4/4/1945 PLACE OF BIRTH : Kota Bharu, Kelantan MARITAL STATUS : Married CITIZEN : Malaysian; No. 133023 HEALTH : Good EDUCATION : Form 1- Form 5 (1958-1962) Sultan Ismail College, Kota Bharu Form 6 (1963-1964) Victoria Institution, Kuala Lumpur Medical Course (1965-1970) University of Singapore DIPLOMAS OBTAINED : Date Diploma June 1970 MBBS (S’pore) July 1975 MRCP (U.K.) July 1980 AM (Malaysia) 1985 FRCP (Edin) 1989 FRCP (Lond) 1990 FRCP (Glasg) June 1997 FAM (Malaysia) October 2000 FRCPCH October 2008 FRCPI MAJOR FIELD OF INTEREST : Tropical Medicine and Infectious Diseases EXPERIENCE AND POSITIONS HELD: December 1975 - March 1979 Paediatrician General Hospital Kuantan, Pahang April 1979 - December 1979 Paediatrician General Hospital

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CURRICULUM VITAE NAME : Choo Keng Ee TELEPHONE 609 7190125 EMAIL/FAX : [email protected] DATE OF BIRTH : 4/4/1945 PLACE OF BIRTH : Kota Bharu, Kelantan MARITAL STATUS : Married CITIZEN : Malaysian; No. 133023 HEALTH : Good EDUCATION : Form 1- Form 5 (1958-1962) Sultan Ismail College, Kota Bharu Form 6 (1963-1964) Victoria Institution, Kuala Lumpur Medical Course (1965-1970) University of Singapore DIPLOMAS OBTAINED : Date Diploma June 1970 MBBS (S’pore) July 1975 MRCP (U.K.) July 1980 AM (Malaysia) 1985 FRCP (Edin) 1989 FRCP (Lond) 1990 FRCP (Glasg) June 1997 FAM (Malaysia) October 2000 FRCPCH October 2008 FRCPI MAJOR FIELD OF INTEREST : Tropical Medicine and Infectious Diseases EXPERIENCE AND POSITIONS HELD: December 1975 - March 1979 Paediatrician General Hospital Kuantan, Pahang April 1979 - December 1979 Paediatrician General Hospital

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Seremban, Negeri Sembilan January 1980 - July 1981 Consultant General Hospital Paediatrician Kuala Terengganu Terengganu August 1981 - June 1985 Consultant General Hospital Paediatrician Kota Bharu Kelantan July 1985 - December 1988 Consultant Hospital Universiti Paediatrician Sains Malaysia Kubang Kerian Kelantan January 1989 -till April 2000 Consultant Paediatrician Kota Bharu Kelantan 1984 -till April 2000 Honorary Hospital Universiti Clinical Sains Malaysia Consultant Kubang Kerian Kelantan January 1992 - 1993 Short Term World Health Consultant Organisation January 1993 -till April 2000 Honorary School of Nursing Lecturer Kubang Kerian Kelantan 1987 - 1988 Paediatric The Medical Journal Reviewer of Malaysia 1986 -till 1999 Examiner MD Universiti Sains Malaysia Kubang Kerian Kelantan 1994 - till 1999 Examiner M.Med Universiti Sains (Paeds) Malaysia Kubang Kerian

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Kelantan 1994 South-East Asia The Children’s invited guest Hospital (6th) Camperdown Sydney, Australia 1993 -till April 2000 Gazetted Member Kelantan State Child Abuse Committee 1995 - 1997 Chairman and Hospital Kota Bharu Co-ordinator QAP Committee 1995, 1997 Examiner M.Med Universiti 2000, 2003 (Paeds) Kebangsaan Malaysia Kuala Lumpur 2003 Examiner M.Med Universiti Malaya (Paeds) Kuala Lumpur 1996 - till now Examiner MRCP (UK)/ MRCPCH 1996 - till 2012 Member National Coordinating Committee MRCP (UK) & MRCPCH Exams 1995 - 1996 Vice-President Malaysian Paediatric Association 1996 - 1997 President Malaysian Paediatric Association 1997 - 1998 Past President Malaysian Paediatric Association

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1998 -2004 Exco Member Malaysian Paediatric Association 1997 -2003 Member, Association of Advisory Board Paediatric Societies of Southeast Asian Region (APSSEAR) 1997 -2000 Member, 5th International Advisory Board Congress of and Resource Tropical Paediatrics Person 1997 - 2003 Member, 10th&11th Asian Congress Advisory Board of Paediatrics and Resource Person 1997 - 2000 Editor-in-Chief Kota Bharu Journal of Medical Sciences 1998 - 2003 Editor-in-Chief Malaysian Journal of Paediatrics and Child Health 1998 - 1999 Chairman Postgraduate

Medical Education Society of Hospital Kota Bharu

2000 -2004 Professor of Universiti Malaysia Paediatrics & Sarawak Child Health 2000 -2004 Visiting Specialist Sarawak General Hospital 2000 - 2003 Phase II Coordinator Faculty of Medicine & Health Sciences Universiti Malaysia Sarawak

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2000 - 2003 Member of Curriculum Faculty of Medcine & Examination Committee & Health Sciences Universiti Malaysia Sarawak 2000 - 2003 Member of Faculty Faculty of Medicine Management Committee & Health Sciences Universiti Malaysia Sarawak 2000-2001 Coordinator of Year 5 Faculty of Medicine Paediatric Posting & Health Sciences

Universiti Malaysia Sarawak 2000 Chairman, Specialist Credentialing Committee on College of Paediatrics

Paediatric Infectious Disease Academy Medicine of Malaysia

2000- Member, Malaysian Medical Council Representing 2004 (Medical Qualifying Board) Universiti Malaysia Sarawak 2001 Member of UNIMAS/SIMC Teaching Representing Hospital Committee Universiti Malaysia Sarawak 2001 - now Lectures/Advisory work Sanofi Pasteur 2001 Member of Library Committee Faculty of Medicine & Health Sciences Universiti Malaysia Sarawak 2002 - 2004 Member Universiti Malaysia Expert Panel for Natural and Applied Sciences Sarawak 2001 Member of Adhoc Panel of Advisors Faculty of Medicine on Postgraduate Studies & Health Sciences Universiti Malaysia Sarawak

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2002 - 2004 Member of Research and Ethical Faculty of Medicine Committee & Health Sciences Universiti Malaysia Sarawak 2002 Travelling Fellow Association of Physicians United Kingdom 2002 Member, Editorial Advisory Board Asia Pacific Vaccine Newsletter 2002 - now Member, Scientific Panel Malaysian Paediatric Survellance Unit (Malaysian Paediatric Association) 2002 Member Committee to review Final Professional Examination Faculty of Medicine & Health Sciences Universiti Malaysia Sarawak 2002 Member (twice) Acreditation Committee Faculty of Medicine & Health Sciences Universiti Malaysia Sarawak 2002-2006 Malaysian Representative Asian Society of Paediatric Infectious Diseases 2003- 2004 Member Medical Education Unit Faculty of Medicine & Health Sciences Universiti Malaysia Sarawak 2003-2004 Member 2nd Asian Congress of Scientific Committee Pediatric Infectious Diseases 2003 Reviewer Journal Acta Tropica

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2004-2006 Member Asian Society of Pediatric Standing Committee Infectious Diseases 2004-2006 Member 3rd Asian Congress of International Scientific Committee Pediatric Infectious Diseases 2006 Member National Sub-Committee on Credentialing of Paediatric Infectious Disease Specialty 2006-2010 Professor of Paediatrics Health Campus School of Medical Sciences Universiti Sains Malaysia Kelantan 2007-2010 Member School of Medical Sciences

Research Committee Health Campus Universit Sains Malaysia

Kelantan 2008/ Member School of Medical Sciences 2009 Panel for Selection of Health Campus Intake of Medical Students Universiti Sains Malaysia Kelantan 2009 Chairman Universiti Sains Malaysia Board of Examiners For MSc & PhD Theses 2009-2010 Chairman, USAINS Health Campus Professional Advisory Committee Universiti Sains Malaysia Kelantan 2009 Member School of Medical Sciences Council of Professors Health Campus For Research Advancement Universiti Sains Malaysia (APEX University) Kelantan

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PAPERS PRESENTED:

1. KM Afzal, KE Choo. Choledochal cyst in children. Malaysia-S'pore Academy of Medicine Conference, Kuala Lumpur, 1979.

2. RP Chand, Gururaj AK, KE Choo. Epilepsy in infancy. Academy of

Medicine Quarterly Scientific Meeting, Kota Bharu, Kelantan. 1987.

3. AR Razif, WA Ariffin, AK Gururaj, M Sepiah, KE Choo. Typhoid fever in Kelantanese children. First International Congress of Tropical Paediatrics, Bangkok. November 8-12, 1987.

4. KE Choo, SP Chuah, WA Ariffin. Neonatal septicaemia in rural Malaysia.

6th Asian Congress of Paediatrics, Tokyo. March 27-31, 1988.

5. AK Gururaj, R Pratap Chand, KE Choo. A clinical and electroencephalographic correlation of epilepsy in infancy. 6th Asian Congress of Paediatrics, Tokyo. March 27-31, 1988.

6. KE Choo, SP Chuah, WA Ariffin. Neonatal sepsis in Malaysia. National

Symposium on Neonatal Care, Kuala Lumpur. June 1988.

7. KK Tan, KE Choo, WA Ariffin, SP Chuah, AK Gururaj. Haemorrhagic disease of infancy in hospitalised Kelantanese children. Symposium on Paediatric Haematology and Oncology, Kuala Lumpur. July 7-9, 1989.

8. J Normah, KE Choo, SJ Oppenheimer, G Selamah. Family studies of G6PD

deficiency in Kelantan. Symposium on Paediatric Haematology and Oncology, Kuala Lumpur. July 7-9, 1989.

9. M Sepiah, WA Ariffin, KE Choo, SJ Oppenheimer. Acute haemolysis in

G6PD deficient children in Kelantan. Symposium on Paediatric Haematology and Oncology, Kuala Lumpur. July 7-9, 1989.

10. S Karnaneedi, WA Ariffin, KE Choo. Congenital dyserythropoetic

anaemia. Symposium on Paediatric Haematology and Oncology, Kuala Lumpur. July 7-9, 1989.

11. KE Choo, WA Ariffin, T Ahmad, WL Lim, AK Gururaj. Purulent

meningitis in children. 19th Congress of International Paediatrics, Paris. July 23-28, 1989. (POSTER)

12. WA Ariffin, KE Choo, SJ Oppenheimer, M Sepiah, J Normah, Z Rozita.

Favism in Malays. Joint Scientific Meeting of the Australian College of

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Paediatrics and the Singapore Paediatric Society with the Canadian Paediatric Society, Singapore. May 16-19, 1990.

13. W Maziah, KE Choo, WA Ariffin. Empyema thoracis in children. Joint

Scientific Meeting of the Australian College of Paediatrics and the Singapore Paediatric Society with the Canadian Paediatric Society, Singapore. May 16-19, 1990. (POSTER)

14. KK Tan, KE Choo, WA Ariffin. Snake bite in Kelantanese children. 5th

Asean Paediatric Federation Conference, Kuala Lumpur. July 27-30, 1990.

15. KE Choo, J Normah, SJ Oppenheimer, G Selamah. G6PD activity in Malays. 7th Asian Congress of Paediatrics, Perth. May 5-10, 1991. (POSTER)

16. KE Choo, WA Ariffin, KH Ong, S Sivakumaran. Aztreonam treatment

failures in typhoid. 7th Asian Congress of Paediatrics, Perth. May 5-10, 1991. (POSTER)

17. KE Choo, AR Razif, WA Ariffin, SJ Oppenheimer, T Abraham. Value of

Widal test in sepsis screen. 7th Asian Congress of Paediatrics, Perth. May 5-10, 1991. (POSTER)

18. Acute respiratory tract infection in children : A community-based study.

MS Lye, D Uma, PF Lai, K Hanjeet, KE Choo, Azmi Shapie, Azmi Hashim, H Wan Mansor, D Fatimah, CY Chong, Nor Azmi, S Thevaraj, Abdul Aziz Mahmud, Jit Singh, Laila Noor, Azizan Aiyub Ghazali, Anuar Bachee. Academy of Medicine Quarterly Meeting, Ipoh, Malaysia. July 28, 1991.

19. N Zainal, KE Choo, AR Razif, WA Ariffin, M Sepiah. Typhoid fever in

children in Kelantan, Malaysia. 1st Asia-Pacific Symposium on Typhoid Fever, Institute for Advanced Studies, University of Malaya, Kuala Lumpur. October 1-3, 1991.

20. WA Ariffin, KE Choo, KH Ong, S Sivakumaran. Aztreonam treatment

failure in typhoid. 1st Asia-Pacific Symposium on Typhoid Fever, Institute for Advanced Studies, University of Malaya, Kuala Lumpur. October 1-3, 1991.

21. WY Lim, KE Choo, AR Razif, WA Ariffin, SJ Oppenheimer, T Abraham.

Usefulness of the Widal Test in childhood typhoid fever. 1st Asia-Pacific Symposium on Typhoid Fever, Institute for Advanced Studies, University of Malaya, Kuala Lumpur. October 1-3, 1991.

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22. KH Ong, A Ismail, KE Choo, ZSA Kader. Clinical field trials on the EIA Dotblot for the diagnosis of typhoid fever. 1st Asia-Pacific Symposium on Typhoid Fever, Institute for Advanced Studies, University of Malaya, Kuala Lumpur. October 1-3, 1991.

23. KE Choo, KH Ong, I Asma. Diagnosis of typhoid : a clinician's dilemma.

1st Asia-Pacific Symposium on Typhoid Fever, Institute for Advanced Studies, University of Malaya, Kuala Lumpur. October 1-3, 1991.

24. KE Choo, WA Ariffin, SJ Oppenheimer, T Abraham. WidalTest. 2nd

Commonwealth Conference on Diarrhea and Malnutrition, New Delhi, India. November 29-December 1, 1991.

25. SP Ram, KE Choo, Prakash Kaur, Low Heng Chin. A 2-year review of

preterm babies with hyaline membrane disease in Kelantan. Quarterly Scientific Meeting of Academy Medicine, Malaysia, Malacca. April 26, 1992.

26. M Mafauzy, KE Choo, NA Rahman, Musalmah, WB Mohamad, BE

Mustaffa. Screening for congenital hypothyroidism using cord blood in a rural region of Malaysia. 4th International Thyroid Symposium, Innsbruck, Austria. September 14-17, 1992.

27. KE Choo, KH Ong, Asma Ismail, SJ Oppenheimer. Dot EIA using 50 KDa

OMP for the rapid serodiagnosis of typhoid fever. 13th International Congress for Tropical Medicine and Malaria, Pattaya, Thailand. November 29-December 4, 1992.

28. KH Ong, A Ismail, KE Choo, ZK Kader. Evaluation of enzyme

immunosorbent assay (Dot EIA) for laboratory diagnosis of typhoid fever. 3rd Western Pacific Congress on Chemotherapy and Infectious Diseases, Bali, Indonesia. December 6-12, 1992.

29. PF Lai, K Hanjeet, KE Choo, MS Lye. Intestinal protozoan infections

among diarrhoeal cases. 29th Annual Scientific Seminar, Malaysian Society of Parasitology and Tropical Medicine, Kuala Lumpur. February 19-20, 1993.

30. R Ismail, SA Sulaiman, KE Choo. Therapeutic drug monitoring of

chloramphenicol in paediatric patients. 10th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Kota Bharu. May 10-11, 1993.

31. KK Phua, PK Das, KE Choo. Detection of hepatitis B virus DNA in hepatitis B surface antigen positive sera using the polymerase chain reaction

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: a better method for measuring infectivity. 10th Scientific Meeting of the Malaysian Society of Pharmacology and Physiology, Kota Bharu. May 10-11, 1993. (POSTER)

32. KE Choo, J Normah, WA Ariffin, SJ Oppenheimer, G Selamah. Cord blood

screening of Glucose-6-Phosphate Dehydrogenase (G6PD) activity in Malay neonates. 1st Asian Pacific Regional Meeting of International Society of Neonatal Screening, Sapporo, Japan. June 21-23, 1993.

33. DVN Vishna, NH Tan, KE Choo. Immunodetection of snake venoms in

serum samples of snake bite victims in Northeast coast of Malaysia. Third Asia-Pacific Congress on animal, plant and microbial toxins, Kuala Lumpur. June 27-July 1, 1993. (POSTER)

34. KK Phua, PK Das, KE Choo, HS Nazim. Comparison of Elisa for hepatitis

B e antigen and PCR for HBV-DNA detection for the measurement of infectivity and pathogenecity in hepatitis B. 4th Combined Meeting Malaysian and Singapore Society of Pathologists, Kubang Kerian. September 11-12, 1993.

35. H Khalid, HN Faizah, KE Choo. Congenital dyserythropoetic anaemia :

description of a case with early presentation. 4th Combined Meeting Malaysian and Singapore Society of Pathologists, Kubang Kerian. September 11-12, 1993. (POSTER)

36. AM Mazidah, A Omar, KE Choo, S Achana. Plasma lipid and lipoprotein

levels of mothers and their newborns. 4th Combined Meeting Malaysian and Singapore Society of Pathologists, Kubang Kerian. September 11-12, 1993. (POSTER)

37. PK Das, KK Phua, KE Choo, S Achana, Nor Hilmi Junoh. Efficacy of

Hepatitis B immunization program in the reduction of HBV carrier rate in Malaysia. IXTH Biennal Scientific Meeting Asian Pacific Association for the Study of the Liver, Kuala Lumpur. January 26-29, 1994.

38. KE Choo, A Ismail, KH Ong, SJ Oppenheimer. Rapid serodiagnosis of

typhoid using a dot EIA. 4th Pan Pacific Congress of Paediatric Gastroenterology and Nutrition, Tokyo. September 5-8, 1994.

39. TH Tang, M Musa, KE Choo, AM Khin, I Yaacob, L Mohd Noh, H Jamil,

NM Ismail, ZF Zainuddin. Detection of mycobacterium tuberculosis in paediatric infection. MIMLS 5th National Scientific Conference, Kuala Lumpur. September 12-14, 1994

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40. KE Choo, AB Ismail, KH Ong, SJ Oppenheimer. Rapid diagnosis of typhoid fever. 1st Scientific Meeting, Ministry of Health, Malaysia, Kuala Lumpur. October 26-28, 1994.

41. A Ismail, KH Ong, KE Choo, ZSA Kader, TA Afifah Ibrahim. Recent

developments in the diagnosis of typhoid fever. 4th Western Pacific Congress on Chemotherapy and Infectious Diseases, Manila. December 4-7, 1994.

42. KK Phua, J Hilmi, PK Das, J Normah, KE Choo, MG Shirley. The

incidence of Hepatitis C viral infection in selected population groups in Kelantan. National Conference on Medical Sciences, Kota Bharu. June 11-12, 1995.

43. PK Das, KK Phua, J Hilmi, KE Choo. A cost-effective analysis of mass

vaccination as opposed to mass screening and selective vaccination of Hepatitis B. National Conference on Medical Sciences, Kota Bharu. June 11-12, 1995.

44. KE Choo, PK Das, KK Phua, J Hilmi. Immunogenecity, efficacy and safety

of a recombinant DNA Hepatitis B vaccine in Kelantanese infants born to Hepatitis B carrier mothers. National Conference on Medical Sciences, Kota Bharu. June 11-12, 1995.

45. A Ismail, KH Ong, KE Choo, ZSA Kader, TA Afifah Ibrahim. Recent

development in the rapid diagnosis of typhoid fever. 17th Annual Convention of the Philippine Society of Microbiology and Infectious Diseases, Manila. November 29-December 1, 1995.

46. Azni Alias, AR Noor, KE Choo, WH Wernsdorfer. Antimalarial drug

sensitivity testing of falciparum malaria in Kelantan using the invitro microtechnique. Malaysian Society of Parasitology and Tropical Medicine, Kuala Lumpur. March 31, 1996.

47. MN Lokman, KE Choo, I Hashim, et al. Deficient memory T cells in

children with tuberculosis in Northeast Peninsular Malaysia. Joint Scientific Meeting of Malaysian Society for Immunology and Malaysian Society of Rheumatology, Kuala Lumpur. April 2, 1996.

48. A Sofiah, I Hussain, LC Ong, KE Choo, MN Musa, TY Wee. A multicenter cross sectional study on meningitis in Malaysia. 4th International Congress of Tropical Paediatrics, Kuala Lumpur. July 7-11, 1996.

49. MN Lokman, TH Tang, F Zainul, KE Choo. Diagnosis of primary

tuberculosis in children by amplification and detection of mycobacterial

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DNA : The Malaysian experience. 4th International Congress of Tropical Paediatrics, Kuala Lumpur. July 7-11, 1996.

50. PC Dam, C Nopparatana, N Jamaludin, N Mohd Yusoff, KE Choo, V

Panich. Spectrum of Beta-Thalassemia mutations in Kelantan. Symposium on Health in Southern Thailand, Songkhla. July 25-26, 1996.

51. PC Dam, C Nopparatana, N Jamaludin, N Mohd Yusoff, KE Choo, V

Panich. Spectrum of Beta-Thalassemia mutations in Kelantan. 21st Annual General Meeting of the Malaysian Society of Pathologists, Kuala Lumpur. August 30-31, 1996. (POSTER)

52. KE Choo, TME Davis, B Singh, J Ibrahim, JL Spencer, A St. John.

Dynamic assessment of the electrocardiographic QT interval during citrate infusion in healthy volunteers. First MOH-AMM Scientific Meeting, Kuala Lumpur. October 30-November 3, 1996.

53. HIM Ismail, A Sofiah, LC Ong, KE Choo, N Musa, KH Teh, HP Ng.

Multicentre study on childhood meningitis. First MOH-AMM Scientific Meeting, Kuala Lumpur. October 30 - November 3, 1996.

54. KE Choo, TME Davis, A Ismail, KH Ong. Longevity of antibody responses

to a salmonella typhi specific outer membrane protein : interpretation of a Dot enzyme immunosorbent assay in an area of high typhoid fever endemicity. 14th International Congress for Tropical Medicine and Malaria, Nagasaki, Japan. November 17-22, 1996.

55. B Singh, KE Choo, W Johnston, TME Davis. Non-radioisotopic glucose

turnover and clearance in Malaysian children with malaria and enteric fever. 14th International Congress for Tropical Medicine and Malaria, Nagasaki, Japan. November 17-22, 1996.

56. A Alias, AR Noor, KE Choo, WH Wernsdorfer. Plasmodium falciparum in

Malaysia : Emergence of multi-drug resistant isolates detected by the WHO in vitro microtechnique. 5th Western Pacific Congress on Chemotherapy and Infectious Diseases. Singapore. December 1-4, 1996.

57. B Singh, KE Choo, J Ibrahim, R Ismail, MJ Hassan, W Johnston, TME Davis. Glucose turnover in children with malaria and typhoid fever. 33rd Annual Scientific Seminar, Malaysian Society of Parasitology and Tropical Medicine, Kuala Lumpur. March 14-15, 1997.

58. K Hanjeet, PF Lai, YM Cheong, KE Choo, MS Lye. Common diarrhoea

among young rural children in Malaysia. 33rd Annual Scientific Seminar.

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Malaysian Society of Parasitology and Tropical Medicine, Kuala Lumpur. March 14-15, 1997.

59. MY Narazah, K Nishiyama, T Shirakawa, KE Choo, J Normah, G Selamah,

I Ilunihayati, M Matsuo, MN Isa. G6PD Mediterranean and G6PD Mahidol mutations in Malay neonatal jaundice. Mutation Detection ‘97. 4th International Workshop. Bruno, Czech Republic. May 29 - June 2, 1997.(POSTER)

60. MN Lokman, A Maheran, N Khairulddin, F Zainul, M Mustafa, TH Tang,

M Jamaruddin, KE Choo. Lymphocytic proliferative response to 30-100kd mycobacterial secreted protein in tuberculosis. 31st Malaysia-Singapore Congress of Medicine, Kuala Lumpur. August 20-24, 1997.

61. MY Narazah, K Nishiyama, T Shirakawa, KE Choo, J Normah, G Selamah,

I Ilunihayati, M Nakano, M Matsuo, MH Zabidi Azhar, MN Isa. G6PD Mediterranean and G6PD Mahidol mutations in Malay neonatal jaundice. Annual Congress of The Malaysian Paediatric Association. Kota Bharu, Kelantan. September 5-8, 1997.

62. H Van Rostenberghe, Nik Zainal Abidin, SS Mutum, KE Choo. Renal

biopsies done in Hospital Universiti Sains Malaysia during the past two years: indications and results for the paediatric age group. Annual Congress of The Malaysian Paediatric Association. Kota Bharu, Kelantan. September 5-8, 1997.

63. A Ismail, TA Tuan Ibrahim, KE Choo, WN Wan Ghazali. Recent advances

in the rapid serodiagnosis of typhoid. 3rd Asia Pacific Symposium on Typhoid Fever and Other Salmonellosis. Bali, Indonesia. December 8-10, 1997.

64. KE Choo, TME Davis, A Ismail, TA Tuan Ibrahim, WN Wan Ghazali.

Comparative sensitivity and specificity of Typhidot and Typhidot-M tests in the diagnosis of enteric fever in Malaysian children. 3rd Asia Pacific Symposium on Typhoid Fever and Other Salmonellosis. Bali, Indonesia. December 8-10, 1997. (POSTER)

65. CM Pim, Chamnong Nopparatana, J Normah, MY Narazah, BS Menon, Vannarat Saechan, Somsak Kanjanaopas, KE Choo. Spectrum of B-thalassaemia mutations in Kelantan. 3rd Asia Pacific Conference on Medical Genetics. Kuala Lumpur. December 2-4, 1997. (POSTER)

66. TME Davis, AE Makepeace, EA Dallimore, KE Choo. Relative bradycardia

is not a feature of enteric fever in children. Australian College of Tropical Medicine Annual Scientific Meeting. Perth,Australia. October, 1-3, 1998.

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67. KE Choo, TME Davis, MA Mansur, E Azman, S Achana, A RusAnida.

Serum lipid profiles in Malay mothers and neonates: a cross-sectional study. Asian Conference on early and childhood nutrition. Kuala Lumpur. November 1-4, 1998. (POSTER)

68. PN Jeyaseelan, KE Choo, TME Davis, A Ismail,, TA Tuan Ibrahim, WNW

Ghazali. Rapid and reliable test for enteric fever: comparative sensitivity and specificity of typhidot and typhidot-M tests in the diagnosis of enteric fever in Malaysian children. 2nd MOH - AMM Scientific Meeting. Kuala Lumpur. November 4-7, 1998.

69. BS Menon, AS Malik, KE Choo, F Mahmud, MD Shukri Abdullah, B

Singh. Cryptosporidium parvum in hospitalised children in Kota Bharu. 6th Western Pacific Congress of Chemotherapy and Infectious Diseases. Kuala Lumpur. November 29 - December 3, 1998. (POSTER)

70. CM Choo, BS Quah, HV Rostenburghe, KE Choo. Risk factors for acute

lower respiratory tract infections in hospitalised children in Kelantan. Fifth National Conference on Medical Sciences. Universiti Sains Malaysia, Kelantan. May 4-5, 1999.

71. MY Narazah, G Selamah, K Nishiyama, K Shirakawa, KE Choo, WMZ

Wan Soriany, M Matsuo. Screening for mutations in Malay Glucose-6-Phosphate Dehydogenase deficient gene. 3rd National Conference of Haematology 2000. Kual Lumpur. April 28-30, 2000. (2nd Best Free Paper)

72. MY Narazah, T Shirakawa,K Nishiyama, G Selamah, KE Choo, IM Nizam,

M Matsuo. Genetic variations of the Glucose-6-Phosphate Dehydrogenase (G6PD) gene in neonatal jaundice in Kelantan Malays, Malaysia. Asian Symposium in Neonatology -- G6PD deficiency and related conditions. Yogyarkata. August,8-9, 2000.

73. Sharifah AI Mokhtar, Ramasamy SP, Jeyaseelan N, Masnizah M, Choo KE. Congenital heart disease in newborns in Kelantan: its spectrum and short term outcomes. 23rd Annual Congress of The Malaysian Paediatric Association. Kuantan, Pahang. August 31-September 2, 2001.

74. Choo KE, Davis TME, Henry RL, Chan LP. Usefulness of C-reactive

protein in early diagnosis of enteric fever. 10th International Congress on Infectious Diseases. Singapore. March 11-14, 2002.

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75. Teh SH, Lee WS, Puthucheary SD, Parasakthi N, Choo KE. Antimicrobial susceptibility and distribution of non-typhoidal Salmonella serovars isolated in Malaysian children. Joint UNIMAS-Sarawak Health Department Medical Colloquium. Kuching, Sarawak August 16-17, 2003.

76. Loi HDK,Yusoff NM,, Shirakawa T, Nishiyama K, Ghazali S, Choo KE,

Orita A, Abdullah WZ, Isa MN, Rostenberghe HV, Matsuo M. Glucose-6-phosphate dehydrogenase (G6PD) variants in Malays in Malaysia. Joint UNIMAS-Sarawak Health Department Medical Colloquium. Kuching, Sarawak August 16-17, 2003.

77. Choo KE, Davis TME, Lau KB, Chew PH, Jenkins A. Features of the

metabolic syndrome are present in the pre-pubertal children of diabetic Malay adults. Annual Meeting of Australian Diabetic Society. Melbourne, Australia September 17-19, 2003. (Poster)

78. Choo KE, Nicoli TK, Bruce LJ, Tanner MJA, A Ruiz-Linares, Povey S,

Unwin RJ, Wrong OM. Recessive renal tubular acidosis in Sarawak caused by band 3 mutations. 11th Asian Congress of Pediatrics. Bangkok, Thailand November 2-7, 2003.

79. Choo KE, Davis TME, Lau KB, Chew PH, Jenkins A. Features of the

metabolic syndrome are present in the pre-pubertal children of diabetic Malay adults. 11th Asian Congress of Pediatrics. Bangkok, Thailand November 2-7, 2003.

80. Davis TME, Choo KE, Lau KB, Chew PH. Clustering of vascular risk

factors in the pre-pubertal children of diabetic and non-diabetic Malay adults. American Diabetic Association 64th Annual Sessions. Orlando, Florida, USA, June 4-8, 2004. (Poster)

81. Teh SH, Davis TME, Choo KE, Lau KB, Chew PH, Jenkins A. Clustering

of vascular risk factors in the pre-pubertal children of diabetic and non-diabetic Malay adults. 38th Singapore-Malaysia Congress of Medicine. Singapore, August 19-22, 2004. (Best Free Paper)

82. Pau W, SSS Huang, Hassan AKR, Choo KE, Ibrahim MI, Davis TME.

Prevalence and predictors of Helicobacter pylori infection in childen and adults from the Penan ethnic minority of Malaysian Borneo. 2nd Asian Congress of Pediatric Infectious Diseases/26th Annual Congress of the Malaysian Paediatric Association. Kota Kinabalu, Sabah, September 2-4, 2004. (Nominee Young Investigator Award)

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83. Awin N, Hussain IMI, Kurup D, Choo KE, Zulikifli I, Nyambat B, Jodar L, Kilgore PE. Introduction of Haemophilus influenzae type B vaccination in Malaysia: Implications for new vaccine introduction in Asia. Second Asian Congress of Paediatric Infectious Diseases/26th Annual Congress of Malaysian Paediatric Association. Kota Kinabalu, Sabah, September 2-5, 2004 (Best Poster).

84. Ahmad Wazir R, Lee YY, Nazri M, Nor Azwany Y, Kamarul Imran M,

Noorizan AM, Choo KE. The influence of sociodemographic factors and hygienic practices on the prevalence of Helicobactor pylori infection among Malay patients undergoing OGDS in Hospital Universiti Sains Malaysia. GUT. Pulau Langkawi, Kedah, August 14-16, 2009 (Poster).

85. Ahmad Wazi R, Lee YY, Nazri M, Nor Azwany Y, Kamarul Imran M,

Noorizan AM, Choo KE. The influence of diet on the prevalence of Helicobacter pylori infection among Malay patients undergoing OGDS in Hospital Universiti Sains Malaysia. GUT. Pulau Langkawai, Kedah, August 14-16, 2009 (Poster).

86. Mohd Suhaimi AW, Nik Khairulddin NK, Mariana D, Mat Zuki MJ, Rosli

I, Che Wan A, Habsah H, Choo KE, Ranjit B, Kilgore P. Hospitalizations and case fatalities due to pneumonia in Kota Bharu, Malaysia, between 2004 and 2008. 14th Congress of Asian Pacific Society of Respirology and 3rd Conjoint Congress of the APSR/ACCP. Seoul, Korea, November 14-18, 2009.

87. Lee YY, Ahmad Wazir R, Maran S, Nazri M, Noorizan AM, Choo KE,

Malaty HM, Graham DY. The role of sociocultural and dietary factors in explaining low prevalence of Helicobacter pylori infection among Malay subjects at northeastern region of Peninsular Malaysia. GASTRO 2009. London, UK, November 21-25, 2009.

88. Mohd Suhaimi AW, Nik Khairulddin NY, Mariana D, Mat Zuki MJ, Rosli

I, Che Wan A, Habsah H, Choo KE, Zaini MN, Zaihan A, Nurahan M, Ranjit B, Kilgore P, M Favorov, Seljan MP. Hospitalizations and case fatality rates due to pneumonia, meningitis and septicemia in Malaysia between 2004 and 2008. 14th International Congress on Infectious Diseases. Miami, Florida, USA, March 9-12, 2010.

89. N Mustapha, YY Lee, AW Ismail, AA Rahim, KI Musa, NA Majid, KE

Choo, SM Raj, HM Malaty, DY Graham. Dietary practices of Malay subjects in north-eastern peninsular Malaysia: a region of low Helicobacter

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pylori prevalence. Asian Pacific Digestive Week 2010. Kuala Lumpur, September 19-22, 2010.

90. N Ariffin, N Ramli, Choo KE, F Taib, H Hassan, NR Ibrahim, A Abd

Rahman, H van Rostenghburghe. Intrahospital variation of the bacteriology of nosocomial infections between the NICU and other ICUs. 32nd Annual Congress of the Malaysian Paediatric Association. Kuala Lumpur, October 16-17, 2010.

INVITED PRESENTATIONS: 1. KE Choo. Use of oral rehydration solution with respect to diarrhoeal diseases

in Malaysia. 1st National Conference of Paediatricians. Kuala Lumpur. September, 1986.

2. KE Choo. The high risk infant. Maternal and Child Health Society of Malaysia

Meeting. Kota Bharu, Kelantan. September 1988. 3. KE Choo. Role of paediatricians in control of diarrhoeal diseases and acute

respiratory infections. 2nd National Conference of Paediatricians. Port Dickson, Negeri Sembilan. November 16-18, 1992.

4. A Ismail, KH Ong, KE Choo, ZA Kader, TAT Ibrahim. A new method for the

rapid diagnosis of typhoid fever. Academic Meeting, Faculty of Medicine, University of Northern Sumatra, Indonesia. May 26, 1994.

5. A Ismail, KH Ong, KE Choo, ZA Kader, TAT Ibrahim. A new method for the

rapid diagnosis of typhoid fever. Annual Congress of the Malaysian Paediatric Association, Penang. June 10-13, 1994.

6. KE Choo. Inservice training and CME in Paediatrics. 3rd National Conference

of Paediatricians. Cameron Highlands, Pahang. October 22-23, 1994. 7. KE Choo. Dot EIA in the rapid diagnosis of typhoid fever. Malaysian Bio-

Diagnostics and Research (MBDr) Road Show in Kuching, Kota Kinabalu, Kuala Lumpur. May 1996.

8. KE Choo. Epidemiology, aetiology and management of acute respiratory

infection. Kementerian Kesihatan Malaysia workshop on acute respiratory infection. Institute of Paediatrics, Kuala Lumpur. April 1, 1998.

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9. KE Choo. Diagnosis of typhoid fever in children. Persidangan Kesihatan Kelantan(Health Conference Kelantan) 1998. Kota Bharu, Kelantan . July 4 – 7, 1998.

10. KE Choo. Childhood typhoid fever. 9th Asean Paediatric Federation Conference.

Singapore. July 9 – 12 , 1998. 11. KE Choo, NY Nik Khairulddin. Snakebite in children: Once bitten twice shy.

Annual Congress of the Malaysian Paediatric Association. Port Dickson, Negeri Sembilan. July 30 – August 2, 1998.

12. KE Choo. Haemophilus Influenzae type b(Hib) immunisation. Malaysian Medical Association – Malaysian Paediatric Association(Kelantan). Kota Bharu, Kelantan. August 28, 1998.

13. KE Choo. Childhood pneumonia. National seminar on clinical update on

management of acute respiratory infection for primary care doctors. Institute of Paediatrics, Kuala Lumpur. September 22-23, 1998.

14. KE Choo. Talk on Acute Respiratory Infection in children. Radio Four,

Angkasapuri, Kuala Lumpur. September 24, 1998. 15. KE Choo. Clinical experience and recent advances on typhoid. Kementerian

Kesihatan Malaysia: Persidangan Kebangsaan Pengurusan Wabak Penyakit. Pulau Pinang. November 22-25, 1998.

16. KE Choo. Epidemiology of invasive Haemophilus influenzae disease in

Malaysia. Asean Expert Bureau on Vaccines. Shah Alam, Malaysia. December 3, 1998.

17. KE Choo. Epidemiology of invasive Haemophilus influenzae disease in

Malaysia. Malaysian Paediatric Association. Johor Bharu, September 3th, 1999; Kuching, September 4th , 1999;Kuala Lumpur, September 5th ,1999;Penang, September 6th, 1999.

18. KE Choo. Acellular pertussis vaccine and injection polio vaccine immunisation

in Malaysia . Asian Expert Bureau on Vaccines. Manila,Philippines. November 2nd , 1999.

19. KE Choo. Diagnosis of typhoid fever. 10th Asian Congress of Paediatrics. Taipei,

Taiwan. March 26-30, 2000. 20. KE Choo. Acute respitatory infection in childhood. Malaysian Medical

Association(Sarawak Branch) Teaching Course for Family Physicians. Kuching, Sarawak. October 6-8, 2000.

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21. KE Choo. Epidemiology of Haemophilus influenzae disease and immunisation.

Symposium on Vaccine Preventable Diseases. Bandar Seri Begawan, Brunei. September 29, 2000.

22. KE Choo. Epidemiology of meningococcal disease in Malaysia. 3rd Meeting of

Asian Expert Bureau on Pediatric Vaccines. Hong Kong, China. December 15, 2000.

23. KE Choo. Typhoid infections in children. The First Paediatric Infectious Disease

Lecture Series (Malaysian Paediatric Association). Kuala Lumpur, Malaysia. March 31- April 1, 2001.

24. KE Choo. Poliomyelitis in Malaysia: Epidemiology and Vaccination. 4th

Meeting of Asian Expert Bureau on Paediatric Vaccines. Beijing, China. September 12, 2001.

25. Rozita Rosli, Nur Atiqah Abdullah, Wong Swee Lan, Norshariza Nordin,

Shamzarina Mohamad, Chan Lee Gaik, Choo Keng Ee. Hospital-based Rotavirus Surveillance in Malaysia. Second Workshop of Asian Rotavirus Surveillance Network. Bangkok, Thailand. May 9-10, 2002.

26. KE Choo. Vaccination. “Hi Doc” Live Show over RTM Sarawak, “FM 91.9

English Service” on 15th June 2002. 27. KE Choo. Recent advances in enteric fever. Paediatric Infectious Disease

Course. Kuching, Sarawak. August 11, 2002. 28. KE Choo. Tuberculosis-Re-emerging disease. 24th Annual Congress of the

Malaysian Paediatric Association. George Town, Penang. September 6-8, 2002. 29. KE Choo. Enteric fever. First Asian Congress of Pediatric Infectious Diseases.

Pattaya, Thailand. November 11-13, 2002. 30. KE Choo. Hib control program in Malaysia. Aventis Pasteur Symposium.

Pattaya, Thailand. November 12, 2002. 31. KE Choo. Cost-effectiveness of Hib vaccination in Malaysia. Asia Vaccines

Standalone Meeting: “Vaccines for all life stages”. Kota Kinabalu, Sabah, Malaysia. March 8-10 2003.

32. Wong Swee Lan, Rozita Rosli, Norshariza Nordin, Shamzarina Mohamad, Chan

Lee Gaik, Choo Keng Ee. Hospital-based Rotavirus Surveillance in Malaysia.

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Third Workshop of Asian Rotavirus Surveillance Network. Hong Kong, China. March 17-18, 2003.

33. KE Choo. Optimising vaccine use: Hib vaccine as a child survival strategy. 3rd

Asian Congress of Pediatric Infectious Diseases. Cebu City, Philippines. March 7-10, 2006.

34. KE Choo. Vaccine Debate – OPV or IPV in polio-free Malaysia? Vaccines

2006. Malaysian Paediatric Association / Cyberjaya University College of Medical Sciences. Bangi-Putra Jaya, Selangor. June 24-25, 2006.

35. KE Choo. Hepatitis B vaccination: Schedule for optimal immunogenicity.

Sanofi Pasteur 1st National General Practitioners Meeting. Saigon, Vietnam. September 1-3, 2006.

36. KE Choo. The Paediatric Traveller: New developments in vaccine

recommendations. National Seminar on Current Issues In Infectious Diseases 2006. Universiti Putra Malaysia, in collaboration with Malaysian Society of Infectious Diseases and Chemotherapy and Malaysian Medical Associtation. Serdang, Kuala Lumpur. November 15-16, 2006.

37. KE Choo. Hepatitis B vaccination in Malaysia: Which schedule? Sanofi Pasteur

General Practitioners Roadshow. Subang, Kuala Lumpur. April 8th , 2007. 38. KE Choo. Hepatitis B vaccination in Malaysia. Which schedule? Sanofi Pasteur

General Practitioners Meeting. Mid-Valley City, Kuala Lumpur. June 24th, 2007. 39. Panel member at First National Paediatric Research Conference. College of

Paediatrics, Academy of Medicine, Malaysia in conjunction with Departments of Paediatrics in University Malaya, Universiti Kebangsaan Malaysia, Universiti Sains Malaysia and Institute of Paediatrics, Hospital Kuala Lumpur. Faculty of Medicine, University Malaya, Kuala Lumpur. August 11th, 2007.

40. KE Choo. Writng manuscripts for publication. Research Workshop, Department

of Medicine, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan. December13th, 2007.

41. KE Choo. Expectations of the paediatric clinical examination. Revision course

on clinical paediatrics. Prep series I. Malaysian Paediatric Association, Kuala Lumpur. March 6-7, 2008.

42. KE Choo. Immunisations and childhood disease. Immunisation Forum. Health

Campus, Universiti Sains Malaysia, Kelantan. March 16th, 2008.

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43. KE Choo. The paediatric traveller: New developments in vaccine recommendations. 42nd Malaysia-Singapore Congress of Medicine, Academy of Medicine of Malaysia, Kuala Lumpur. July 31st-August 3rd , 2008.

44. KE Choo. OPV or IPV in polio-free Malaysia? & Hepatitis B immunisation:

Which is the optimum schedule? Sanofi Pasteur/Sanofi Aventis Elite Continuous Medical Education Program for General Practitioners. Pulau Tioman, Pahang. August 15-16, 2008.

45. KE Choo. Snake Bite. Department of Accident & Emergency, School of

Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan. December 2nd, 2008.

PUBLICATIONS: 1. CT Lim, KE Choo, MK Afzal. Cardiofacial syndrome. J Singapore Paediatr

Soc 1978;20:232-236. 2. CT Lim, KE Choo. Wilson's disease. J Singapore Paediatr Soc 1979;21:99-

102. 3. Afzal MK, Ee CK, Kei SS. A case of short rib polydactyly. J Singapore

Paediatr Soc 1979;21:103-106. 4. MK Afzal, KE Choo. Lethal neonatal dwarfism. Med J Malaysia 1980;35:64-

67. 5. S Su, KE Choo. Plesiomonas Shigelloides meningitis in newborn. J Singapore

Paediatr Soc 1981;23:156-159. 6. KE Choo. Goltz syndrome. J Singapore Paediatr Soc 1983; 25:81-84. 7. Ee CK. Hypomelanosis of Ito. Med J Malaysia 1983;38:167-169. 8. M Jegathesan, M Singh, KE Choo, J Mohan, S Wong, AJ Ng, A Louis.

Hospital based studies of acute respiratory infections in children in Malaysia-WHO.

9. AK Gururaj, P Chand, MA Koothoor, KE Choo. Kocher Debree Semalaigne

syndrome. J Singapore Paediatr Soc 1987;29:168-171. 10. AK Gururaj, C Pratap, KE Choo. Infantile seizures in Kelantan : a clinico-

EEG study. Diagnosa 1988;2:9-14.

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11. K Anuar, KE Choo, T Abraham, GM Ling. Amoebic liver abscess. Diagnosa

1988;2:35-37. 12. KE Choo, WA Ariffin, SP Chua. Neonatal septicaemia in Kelantan, Malaysia.

Ann Academy Med Singapore 1988;17:438-442. 13. AK Gururaj, R Pratap Chand, KE Choo. Epilepsy in infancy. Singapore Med

J 1988;29:433-437. 14. KE Choo, A Razif, WA Ariffin, M Sepiah, AK Gururaj. Typhoid fever in

hospitalised children in Kelantan, Malaysia. Ann Trop Paediatr 1988;8:207-212.

15. S Karnaneedi, KE Choo, WA Ariffin, M Norimi. Phenylketonuria in a six year old Malay boy. Med J Malaysia 1989;44:248-251.

16. J Normah, KE Choo. Favism and G6PD deficiency—a case report. Malaysian

J Pathol 1989;11:78 (abstract). 17. KE Choo, A Sharifah, WA Ariffin, M Mafauzy. Generalised lipodystrophy.

Singapore Med J 1990;31:290-292. 18. KK Tan, KE Choo, WA Ariffin. Snake bite in Kelantanese children : a five

year experience. Toxicon 1990;225-230. 19. KE Choo, WA Ariffin, T Ahmad, WL Lim, AK Gururaj. Pyogenic meningitis

in hospitalised children in Kelantan, Malaysia. Ann Trop Paediatr 1990;10:89-98.

20. AK Gururaj, KE Choo, WA Ariffin, A Sharifah. A clinical, laboratory and

echocardiographic profile of children with acute rheumatic fever. Singapore Med J 1990;31:364-367.

21. WA Ariffin, KE Choo, SJ Oppenheimer, M Sepiah, N Jamaludin, S Ghazali.

Favism in Malays. J Paediatr Child Health 1990;26:306 (ABSTRACT). 22. KE Choo, WA Ariffin, KH Ong, S Sivakumaran. Aztreonam failure in typhoid

fever. Lancet 1991;37:498. (LETTER) 23. J Normah, KE Choo, SJ Oppenheimer, G Selamah. Glucose-6-phosphate

dehydrogenase (G6PD) enzyme activity in normal, hemizygote and heterozygote Kelantanese Malays. J Paediatr Child Health 1991;27:376-379.

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24. MS Lye, D Uma, PF Lai, K Hanjeet, KE Choo, Azmi Shapie, Azmi Hashim, H Wan Mansor, D Fatimah, CY Chong, Nor Azmi, S Thevaraj, Abdul Aziz Mahmud, Jit Singh, Laila Noor, Azizan Aiyub Ghazali, Anuar Bachee. Acute Respiratory Infections (ARI) in children : A community-based intervention study. Institute for Medical Research Kuala Lumpur, Malaysia, Annual Report 1991;p21-2.

25. KE Choo, P Kandasamy. Quality assurance programme in the management of

typhoid fever. Diagnosa 1992;6:19-23. 26. KE Choo, SJ Oppenheimer, AR Razak, WA Ariffin, T Abraham. Sensitivity

and specificity of the Widal test for childhood typhoid fever. J Paediatr Hong Kong 1992 (March).

27. WA Ariffin, KE Choo, S Karnaneedi. Cassava (Ubi Kayu) poisoning in children. Med J Malaysia 1992;47:231-234.

28. Dinesh Halder, WA Ariffin, Radzi Abdullah, KE Choo. Neonatal meloidosis.

Singapore Med J 1993;34:85-86. 29. KE Choo, AR Razak, SJ Oppenheimer, WA Ariffin, J Lau, T Abraham.

Usefulness of the Widal test in diagnosing childhood typhoid fever in endemic areas. J Paediatr Child Health 1993;29:36-39.

30. R Ismail, SA Sulaiman, KE Choo. Therapeutic drug monitoring of

chloramphenicol in paediatric patients. Asia Pacific J Pharmacol 1993;8:S35. (ABSTRACT)

31. KK Phua, PK Das, KE Choo, M Nazim, E Gowans. Detection of hepatitis B

virus DNA in hepatitis B surface antigen positive sera using the polymerase chain reaction. A better method for measuring infectivity. Asia Pacific J Pharmacol 1993;8:S52. (ABSTRACT)

32. DVN Vishna, NH Tan, KE Choo. Immunodetection of snake venoms in serum

samples of snakebite victims in northeast coast of Malaysia. Toxicon 1994;32:550. (ABSTRACT)

33. KE Choo, SJ Oppenheimer, Asma B Ismail, KH Ong. Rapid serodiagnosis of

typhoid fever by dot enzyme immunoassay in an endemic area. Clin Infect Dis 1994;19:172-6.

34. KE Choo, KK Tan, SP Chuah, WA Ariffin, A Gururaj. Haemorrhagic disease

in newborn and older infants : a study in hospitalized children in Kelantan, Malaysia. Ann Trop Paediatr 1994;14:231-237.

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35. TS Saraswathy, M Sinniah, WS Lee, MS Lye, KE Choo, H Junoh. Poliomyelitis and measles serosurvey in northern Malaysia. South East Asian J Trop Med Public Health 1994;25:565-568.

36. Asma B Ismail, KH Ong, KE Choo, Zainoodin SA Kader, Tuan Afifah Tuan

Ibrahim. Recent developments in the diagnosis of typhoid fever. Supplement to JAMA Southeast Asia 1994;10:321-323.

37. MS Lye, U Devi, KPF Lai, H Kaur, RC Nair, KE Choo. Acute respiratory

infection in Malaysian children. J Trop Pediatr 1994;40:334-340. 38. W Maziah, KE Choo, JG Ray, WA Ariffin. Empyema thoracis in hospitalized

children in Kelantan, Malaysia. J Trop Pediar 1995;41:185-188. 39. TME Davis, B Singh, KE Choo, I Jamal, JL Spencer, A St. John. Dynamic

assessment of the electrocardiographic QT interval during citrate infusion in healthy volunteers. Br Heart J 1995;T3:523-526.

40. A Wahab, J Hanifah, KE Choo. Bruton's agammaglobulinaemia in a child

presenting with cryptococcal empyema thoracis and periauricular pyogenic abscess. Singapore Med J 1995;36:686-689.

41. WA Ariffin, S Karnaneedi, KE Choo, J Normah. Congenital dyserythropoietic

anaemia : report of three cases. J Paediatr Child Health 1996;32:191-193. 42. MS Lye, RC Nair, KE Choo, H Kaur, KPF Lai. Acute Respiratory tract

infection : a community-based intervention study in Malaysia. J Trop Paediatr 1996;42:138-143.

43. KE Choo, TME Davis, MA Mansur, E Azman, S Achana. Serum lipid profiles

in Malay mothers and neonates : a cross sectional study. J Paediatr Child Health 1996;32:428-432.

44. D Halder, AS Malik, BS Quah, KE Choo. Neonatal septic arthritis. Southeast

Asian J Trop Med Public Health 1996;27:600-605. 45. SP Ram, KE Choo. A two year review study of respiratory distress syndrome

- in Kelantanese neonates in Malaysia. J Singapore Paediatr Society 1996;38:162-166.

KE Choo, TME Davis, A Ismail, KH Ong. Longevity of antibody responses to salmonella typhi - specific outer membrane protein : interpretation of a Dot enzyme immunosorbent assay. Am J Trop Med Hyg 1997; 57:656-659.

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45. TME Davis, B Singh, KE Choo, J Ibrahim, SA Sulaiman, ZA Kadir, R Ismail. Dynamic assessment of parathyroid function in acute malaria. J Internal Medicine 1998; 243:349-354.

46. R Ismail, LK Teh, EK Choo. Chloramphenicol in children: dose, plasma levels

and clinical effects. Ann Trop Paediatr 1998; 18:123-128. 47. IHM Ismail Hussain, A Sofiah, LC Ong, KE Choo, MN Musa, KH Teh, HP

Ng. Haemophilus influenzae meningitis in Malaysia. Pediatr Infect Dis J 1998; 17:S189-S190.

48. B Singh, KE Choo, J Ibrahim, W Johnston, TME Davis. Non-radioisotopic

glucose turnover in children with falciparum malaria and enteric fever. Trans R Soc Trop Med Hyg 1998; 92: 532-537.

49. CM Choo, BS Quah, HV Rostenberghe, KE Choo. Risk factors for acute lower

respiratory tract infections in hospitalised children in Kelantan. Malaysian J Paediatr Child Health 1998;10(2):1-7.

50. A Ismail, TA Tuan Ibrahim, KE Choo, WN Wan Ghazali. Recent advances in

the rapid diagnosis of typhoid. Med J Indonesia 1998;7(Suppl 1):39-43. 51. K Hanjeet, PK Lai, YM Cheong, KE Choo, MS Lye. Aetiology of diarrhoea

among young rural children in Malaysia. Trop Biomed 1998; 15: 7-14. 52. NY Nik Khairulddin, KE Choo, MR Johari. Epidemiology of Haemophilus

influenzae invasive disease in hospitalised Kelantanese children, 1985-1994. Singapore Med J 1999; 40 : 96-100.

53. KE Choo, TME Davis, A Ismail, TA Tuan Ibrahim, WNW Ghazali. Rapid and

reliable serological diagnosis of enteric fever: a comparative sensitivity and specificity of Typhidot and Typhidot-M tests in febrile Malaysian children. Acta Tropica 1999; 72:175-83.

54. TME Davis, AE Makepeace, EA Dallimore, KE Choo. Relative bradycardia is

not a feature of enteric fever in children . Clin Infect Dis 1999; 28:582-86. 55. TH Tang, M Musa, ZF Zainuddin, KE Choo, MN Lokman, KA Myat, I

Yaacob, H Ismail, M Mustapha. Use of polymerase chain reaction for improved diagnosis of tuberculosis in children. Asia Pacific J Mol Biol Biotech 1999; 7(1) : 47-51.

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56. IHMI Hussain, M Syed Aljunid, A Sofia, LC Ong, KE Choo, MN Musa, KH Teh, HP Ng. Cost-benefit analysis of Haemophilus influenzae vaccination programme in Malaysia. Bulletin Kesihatan Masyarakat 1999; 5:79-89.

57. NM Yusoff, T Shirakawa, K Nishiyama, KE Choo, G Selama, I Ilunihayati, M

Nakano, MH Zabidi Azhar, Mohd Yunus, J Normah, MN Isa, M Matsuo. Genetic variations in the Glucose-6-phosphate Dehydrogenase gene in neonatal jaundice in Kelantan Malays. Malaysian J Paediatr Child Health 2000; 12:1-7.

58. KE Choo, TME Davis, RL Henry, LP Chan. Serum C-reactive protein

concentrations in Malaysian children with enteric fever. J Trop Paediatr 2001; 47: 211-4.

59. BS Menon, S Abdullah, F Mahamud, UM Morgan, AS Malik, KE Choo. Low

prevalence of Cryptosporidium parvum in hospitalized children in Kota Bharu, Malaysia. Southeast Asian J Trop Med Public Health 2001; 32(2): 319-22.

60. NM Yusoff , T Shirakawa, K Nishiyama, S Ghazali, CK Ee , A Orita, WZ

Abdullah, MN Isa, H van Rostenburghe, M Matsuo. Molecular heterogeneity of glucose-6-phosphate dehydogenase deficiency in Malays in Malaysia. Intl J Haematol 2002;76:149-52.

61. WS Lee, SD Puthucheary, N Parasakthi, KE Choo. Antimicrobial

susceptibility and distribution of non-typhoidal Salmonella serovars isolated in Malaysian children. J Trop Paediatr 2003; 49: 37-41.

62. NM Yusoff , T Shirakawa, K Nishiyama, Ee CK, MN Isa, M Matsuo. G6PD

Vianchang and G6PD Mediterranean are the main G6PD variants in G6PD deficiency in the Malay population of Malaysia. Southeast Asian J Trop Med Public Health 2003: 34 (Suppl 3): 135-7.

63. HDK Loi, AS Pahr, SK Subramaniam, KE Choo, HP Ng. Neonatal post –

intubation subglottic stenosis. Med J Malaysia 2004; 59: 126-8. 64. TME Davis, CK Ee. Obesity and the Metabolic Syndrome in children and

adolescents. N Engl J Med 2004;351:1147. (LETTER) 65. SSS Huang, AKR Hassan, KE Choo, MI Ibrahim, TME Davis. Prevalence and

predictors of Helicobacter pylori infection in childen and adults from the Penan ethnic minority of Malaysian Borneo. Am J Trop Med Hyg 2004;71(4):444-50.

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66. KE Choo, TK Nicoli, LJ Bruce, MJA Tanner, A Ruiz-Linares, OM Wrong. Recessive distal renal tubular acidosis in Sarawak caused by band 3 mutations. Pediatr Nephrol 2006;21:212-7. Epub 2005 Oct 27.

67. HDK Loi, KT Wong, KE Choo. Juvenile acid maltase deficiency. Malaysian J Paediatr Child Health 2005;14;58-63.

68. Deposited with GENBANK at National Center For Biotechnology Information

(NCBI), National Institutes Of Health (NIH) (USA) a new mutation: Band_3_UNIMAS. (Accession number DQ419529)

69. KE Choo, KB Lau, WA Davis, PH Chew, AJ Jenkins, TME Davis.

Cardiovascular risk factors in prepubertal Malays: Effects of diabetic parentage. Diabetes Research and Clinical Practice 2007;76:119-125. Epub 2006 September 18.

70. SM Raj, YY Lee, KE Choo, AM Noorizan, A Zulkifli, M Radzi, SC Ang.

Further observations in an area with an exceptionally low prevalence of Helicobacter pylori infection. Trans R S Trop Med Hyg 2008;102; 1163-1164. Epub 2008 August. (LETTER)

71. SM Raj, KE Choo, AM Noorizan, YY Lee, DY Graham. Evidence against H

pylori being related to childhood asthma. J Infect Dis 2009;199(6):914-915. (LETTER)

72. AA Rahim, YY Lee, NA Majid, KE Choo, SM Raj, MH Derakhshan, DY

Graham. Helicobacter pylori infection among Aborigines (the Orang Asli) in the northeastern region of Peninsular Malaysia. Am J Trop Med Hyg 2010; 83(5): 1119-1122. (USM Sanggar Sanjung Prize/Award 2010)

73. YY Lee, AW Ismail, N Mustapha, Musa KI, NA Majid, KE Choo, SM Raj,

MH Derakhshan, HM Malaty, DY Graham. Soicio-cultural and dietary practices among Malay subjects in the north-eastern region of Peninsular Malaysia: a region of low prevalence of Helicobacter pylori infection. Helicobacter 2012; 17(1):54-61.

74. S Khositseth, LJ Bruce, SB Walsh, WM Bawazir, GD Ogle, RJ Unwin, MK

Thong, Sinha R, KE Choo, et al. Tropical Distal Renal Tubular Acidosis:Clincal and epidemiological studies in 78 patients. QJM 2012;105(9):861-77.

75. S Maran, YY Lee, SH Xu, SM Raj, Abdul Majid NA, KE Choo, BA Zilfalil,

DY Graham. Towards understanding the low prevalence of Helicobacter pylori in Malays: Genetic variants among Helicobacter-negative ethnic Malays in the

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north-eastern region of Peninsular Malaysia and the Han Chinese and South Indians. J Dig Dis 2013; 14(4):196-202.

RESEARCH GRANTS: 1. Title of project: Hospital-based studies of acute respiratory infections in children

in Malaysia. Grant: World Health Organisation US$10 000. Members: M Jegathesan, M Singh, KE Choo, J Mohan, S Wong, AJ Ng, A Louis. Date:1985-1986.

2. Title of project: The epidemiology of rheumatic fever and a cohort study towards

eradication. Project code: R0094. IRPA Grant (5th Malaysia Development Plan). RM$695 171. Members: Ibrahim Abdullah, Siva Sivakumaran, Abdul Aziz Baba, Choo Keng Ee, Mazidah Ahmad Mansur, Ismail Yaacob, S Mahendra Raj, Daw Win Kyi, Mustaffa Embong. Date: 1/1/1988-31/12/1995.

3. Title of project: Pengawasan pertahanan parasit malaria terhadap drug

antimalarial di utara Semenanjung Malaysia. Project code: R0132. IRPA Grant (5th Malaysia Development Plan). RM309 317. Members: Abdul Rahman Haji Mohd Noor, Rusli Ismail, SJ Oppenheimer, Azni Alias, Wan Ariffin Abdullah, Hamzah Che Mat, Choo Keng Ee, Mokhtar Noor. Date: 1/1/1989-31/12/1992.

4. Title of project: The comparison of aztreonam to chloramphenicol in the

management of salmonella septcaemia (multicentre study). Project code: A0060. Grant from SQUIBB (USA). RM25 000. Members: Wan Ariffin Abdullah, Siva Sivakumaran, Ong Kok Hai, Choo Keng Ee. Date: 31/5/1987-31/12/1988.

5. Title of project: Application of biotechnology in the development of rapid

diagnosis to enteric fever. Project code: R0364. IRPA Grant (7th Malaysia Development Plan) RM 318 600. Members: Asma Ismail, Ashraful Jallaluddin Haq, Alam Sher Malik, Abdul Rahman Isa, Choo Keng Ee. Date: 16/1/1996- 29/6/1999.

6. Title of project: Application of biotechnology for the development of rapid

antigen detection test for Capmpylobacter jejuni. Project code: R0367. IRPA Grant (7th Malaysia Development Plan). RM 222 000. Members: Mohd Zaki Salleh, Asma Ismail, Zabidi Azhar Mohd Hussein, Zainul Fadziruddin, Choo Keng Ee. Date: 1/16/1996-29/6/1999.

7. Title of project: Perubahan kepekatan glukosa darah dalam kanak-kanak yang

menghidap malaria falsiparum akut. Project code: Universiti Sains Malaysia Grant (Project code:P0981) RM19 200. Members: Balbir Singh, Jamal Ibrahim, J Spencer, Choo Keng Ee, Siti Amrah Sulaiman, TME Davis. A St John. Date: 1/4/1993-30/5/1995.

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8. Title of project: Korelasi sub-kumpulan limfosit CD2-/CD4+ pada kanak-kanak menghidap tuberculosis dengan a) malpemakanan, b) limfadeno. Universiti Sains Malaysia Grant (Project code: P1084) RM20 000. Members: Lokman Mohd Noh, Bina S Menon, Choo Keng Ee, Nurul Azman Alias, Zahari Kassim, Zabidi Azhar Mohd Hussein, Ishak Mat. Date: 1/2/1994-29/4/1996.

9. Title of project: The study of glucose-6-phosphate dehydrogenase (G6PD) gene

by restriction enzyme digestion in the Kelantanese population. University Sains Malaysia Grant (Project code: P1138) RM 17 200. Members: Narazah Mohd Yusoff, Choo Keng Ee, Normah Jamaluddin, Mohd Yunus @ Kyaw Tun., Zabidi Azhar Mohd Hussein. Date: 31/8/1994-29/4/1997.

10. Title project: Study of functional epitopes of mycobacterium tuberculosis

associated with immunity. Project code: R0358. IRPA Grant (7th Malaysia Development Plan) RM207 550. Members: Lokman Mohd Noh, Zainal Fadziruddin, Musalmah Mazlan, Zabidi Azhar Mohd Hussein, Choo Keng Ee, Mustaffa Musa. Date: 16/1/1999-29/6/1999.

11. Title of project: Serum cholesterol profiles in diabetic and non-diabetic Malay

adults and their children: A cross-sectional study. Universiti Malaysia Sarawak Short-Term Grant (Project code 240/2000 (31)) RM 20 000 and University Western Australia Small Grants Scheme (unknown amount). Members: KE Choo, TME Davis, PH Chew. Date: 12/2000-7/2003.

12. Title of project: Disease burden of rotavirus diarrhoea in children in Malaysia:

To assess the need for rotavirus immunisation. Bill & Melinda Gates Fund. US$10 000. Members: RK A Razak, NA Ng Abdullah, KE Choo, LG Chan. Date: 2001-2003.

13. Title of project: The association of Southeast Asian Ovalocytosis (SAO), distal

renal tubular acidosis (dRTA) and AE1 mutations in Sarawak and East Malaysia. Grant from St Peter’s Trust, UK. £46 863. Grant awarded for “Gene analysis of patients with distal renal tubular acidosis (dRTA) and renal stone disease”, awarded to A Ruiz-Linares, S Povey, R Unwin, O Wrong. Date: 2002-2003.

14. Title of project: Prevalence and predictors of Helicobacter pylori infection

among Penan children and adults in Sarawak using stool antigen-based assay. Two Universiti Malaysia Sarawak Short-Term Grants: Project codes 282 (2000)(29), and 315(2002)(52). RM 40 000. Members: SSS Huang, KE Choo, AKR Hassan. Date: 2001-2004.

15. Title of project: Predicting and modeling the relationship between the cholera

outbreaks and climatic conditions in Limbang, Sarawak. Universiti Malaysia

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Short-Term Grant. RM 20 000. Members: D Sagin, KE Choo, CJ Laman. Date: 2001-2002.

16. Title of project: Susceptibility of Helicobacter pylori infection among

Kelantanese population. RU Grant. RM 181 671 19. Members: N Abdul Majid, KA Al-Jashamy, YY Lee, SS Mohd Noor, R Sapian, NKB Yahya, KI Musa, Z Alwi, KE Choo. Date: 2007-2010.

17. Title of project: Active rotavirus gastroenteritis surveillance study in Malaysia

(part of Asian Rotavirus Surveillance Network [ARSN]): Phase III study. MerckSharpDome grant RM$186 872. Members: Lee WS, Chai PF, Jimmy Lee KF, Sazaly Abu Bakar, Zuridah Hassan, Rozita Rusli, Gulprit, Choo KE. Date 2008-2009.

18. Title of project: A study on the whole genome gene expression profile of Malay

patients with and without helicobacter pylori associated chronic atrophic gastritis in Kelantan. Ministry of Higher Education Fundamental Research Grant Scheme (FRGS) (Project code 203/PPSP/6171121) RM137 500. Members: YY Lee, MA Zilfalil, AM Noorizan, KE Choo, A Sarimah, TA Sharifah Emelia. Date: 1/11/2008 - 31/10/2011.

19. Title of project: A retrospective study to assess the clinical burden of

community-acquired pneumonia (CAP) and invasive pneumococcal disease (IPD) in Malaysia. Grant sponsored by Wyeth Pharmaceuticals Inc, USA. RM53 862.55.Members: AW Mohd Suhaimi, KE Choo, N Abdul Rahman, H Che Wan Aminuddin, H Habsah, NM Nik Munirah, MN Zaini, I Zulkifli, P Kilgore, R Batuwanthudawie.(Part of multinational study also involving Korea, Taiwan, Hong Kong, Vietnam, Thailand, Brazil, Argentina, Chile, Sweden, Italy, etc.) Coordinated by International Vaccine Institute, Korea. Date 2008-2009.

20. Title of project: Invasive pneumococcal disease in Universiti Sains Malaysia:

12 years review (1998-2010). Members: Mangaletchmy Krishana, KE Choo, AW Mohd Suhaimi. H Habsah.

21. Title of project: Five year review (2005-2009) of antibiotic resistance of

bacteria cultured from patients in Neonatal Intensive Care Unit. USM Incentive Grant RM5 000. Members: KE Choo, HV Rostenberghe, Ramli N, Ibrahim R, Hassan H, A Rahman A. Date 2010.

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CONTRIBUTION TO BOOKS: 1. Typhoid fever:Strategies for the 90’s. T Pang, CL Koh, SD Puthucheary (eds).

Singapore : World Scientific Publishing Co Pte Ltd 1992. 2. New trends in neonatal screening. Nobuo Takasugi, Hiroshi Naruse (eds).

Sapporo : Hokkaido University Press 1994. 3. 1st National Consensus Guidelines for Antiretroviral Treatment 19. Aids

Action Committee, Malaysian Medical Association 1998. 4. Role of New Vaccines in Children. EL Lee, KE Choo, A Omar, AH Omar,

KK Tan, IH Sendut. College of Paediatrics, Academy of Medicine Malaysia 2001.

5. Clinical Practice Guidelines on Acute Gastroenteritis in Children. CM Boey,

KE Choo, M Khor, EL Lee, CB Lim, NA Abdullah, AJ Mohan, CT Koh, WS Lee, NA Majid, MK Oon. College of Paediatrics, Academy of Medicine Malaysia 2001.

6. Malaysian Immunisation Manual 2001. EL Lee, KE Choo (eds). College of

Paediatrics, Academy of Medicine Malaysia 2001(1st edition), 2008 (2nd edition)

7. Handbook of Hospital Paediatrics. WS Lee, MK Thong, CP Wong (eds).

Unipress Publishing, Kuala Lumpur 2005 (1st edition), 2008 (2nd edition). 8. Paediatric Protocols for Malaysian Hospitals. Hussain Imam HMI, HP Ng

(eds). Ministry of Health Malaysia/Perniagaan MMD, Selangor 2009 (2nd edition).

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AWARDS: 1. PSK (Kelantan) (1990) 2. Excellent Service Award (1993) 3. KMN (1994) 4. JSM (2000) 5. Outstanding Paediatrician in Asia Award (2006) 6. Pencalon Pensyarah Klinikal Pilihan Pelajar 2009 (Persatuan Alumni Doktor USM) 7. Anugerah/Award Sanggar Sanjung USM 2010 (Penerbitan) MEMBERSHIP OF SOCIETIES: 1. Member of Academy Medicine, Malaysia 2. Member of Malaysian Paediatric Association (life member) 3. Member of Malaysian Medical Association 4. Member of Asian Society of Paediatric Infectious Diseases 5. Member of International Society of Infectious Diseases