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1 CURRICULUM VITAE OREGON HEALTH & SCIENCE UNIVERSITY NAME Danny O. Jacobs M.D., M.P.H., F.A.C.S. DATE June 21, 2021 I. PRESENT POSITION AND ADDRESS Position: President Academic Rank: Professor II. EDUCATION Undergraduate and Graduate 1971 – 1975 A.B., Biology, Harvard University, Boston, MA 1989 M.P.H. (Biostatistics), Harvard University, School of Public Health, Boston, MA Postgraduate 1975 – 1979 M.D., Washington University, St. Louis, MO 1979 – 1980 Intern in Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 1980 –1985 Resident, General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 1982 –1984 Research Fellow in Nutrition and Metabolism, Harrison Department of Surgical Research, Hospital of the University of Pennsylvania, Philadelphia, PA 1985 – 1986 Chief Resident, General Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 1986 – 1988 Research Fellow in Surgical Nutrition and Metabolism, Department of Surgery, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA CERTIFICATION: American Board of Surgery, 032575 March 2008, expiration December 2018 National Board of Nutrition Support – April 2003 LICENSURE INFORMATION: Pennsylvania MD025534E, July 1981 Massachusetts 58073, inactive, issued July 1987 Nebraska 21377, inactive, issued April 2000 Iowa MD34613, inactive, issued May 2002 North Carolina 200301365, inactive, issued November 2003 Texas R0255, active, expires November 2021 Oregon MD194004, active, expires December 2021

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CURRICULUM VITAE OREGON HEALTH & SCIENCE UNIVERSITY

NAME Danny O. Jacobs M.D., M.P.H., F.A.C.S. DATE June 21, 2021

I. PRESENT POSITION AND ADDRESS Position: President Academic Rank: Professor II. EDUCATION Undergraduate and Graduate 1971 – 1975 A.B., Biology, Harvard University, Boston, MA 1989 M.P.H. (Biostatistics), Harvard University, School of Public Health, Boston, MA Postgraduate 1975 – 1979 M.D., Washington University, St. Louis, MO

1979 – 1980 Intern in Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 1980 –1985 Resident, General Surgery, Hospital of the University of Pennsylvania,

Philadelphia, PA 1982 –1984 Research Fellow in Nutrition and Metabolism, Harrison Department of Surgical

Research, Hospital of the University of Pennsylvania, Philadelphia, PA 1985 – 1986 Chief Resident, General Surgery, Hospital of the University of Pennsylvania,

Philadelphia, PA 1986 – 1988 Research Fellow in Surgical Nutrition and Metabolism, Department of Surgery,

Harvard Medical School, Brigham and Women’s Hospital, Boston, MA CERTIFICATION:

American Board of Surgery, 032575 March 2008, expiration December 2018 National Board of Nutrition Support – April 2003

LICENSURE INFORMATION: Pennsylvania MD025534E, July 1981 Massachusetts 58073, inactive, issued July 1987 Nebraska 21377, inactive, issued April 2000 Iowa MD34613, inactive, issued May 2002 North Carolina 200301365, inactive, issued November 2003 Texas R0255, active, expires November 2021

Oregon MD194004, active, expires December 2021

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III. PROFESSIONAL EXPERIENCE

Academic 1980 – 1985 Assistant Instructor of Surgery

University of Pennsylvania School of Medicine Philadelphia, PA

1985 – 1986 Instructor of Surgery

University of Pennsylvania School of Medicine Philadelphia, PA

1986 – 1988 Research Fellow in Surgery

Harvard Medical School Boston, MA

1989 – 1992 Assistant Professor of Surgery

Harvard Medical School Boston, MA

1993 – 1999 Associate Professor of Surgery

Harvard Medical School Boston, MA

1998 – 2000 Scientific Advisory Committee

General Clinical Research Center Brigham and Women’s Hospital Boston, MA

2000 – 2003 Professor and Chair

Department of Surgery Creighton University, School of Medicine Omaha, NE

2001 – 2003 First Arnold W. Lempka Distinguished Professor of Surgery

Creighton University School of Medicine Omaha, NE

2007 – 2012 David C. Sabiston, Jr., Professor, Department of Surgery

Duke University Medical Center Durham, NC

2012 – 2018 Thomas N. & Gleaves T. James Distinguished Chair

The University of Texas Medical Branch Galveston, TX

2012 – 2018 Professor with tenure, Institute for Translational Sciences

The University of Texas Medical Branch Galveston, TX

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2012 – 2018 Professor with tenure, Department of Preventive Medicine & Community Health The University of Texas Medical Branch Galveston, TX

2012 – 2018 Professor with tenure, Department of Surgery The University of Texas Medical Branch Galveston, TX 2012 – 2018 Professor with tenure Institute for Translational Sciences The University of Texas Medical Branch Galveston, TX 2012 – 2018 Professor with tenure Department of Preventive Medicine & Community Health The University of Texas Medical Branch Galveston, TX 2012 – 2018 Professor with tenure Department of Surgery The University of Texas Medical Branch Galveston, TX 2013 – Present Senior Fellow Sealy Center on Aging The University of Texas Medical Branch Galveston, TX 2018 – Current Professor of Surgery

Department of Surgery Oregon Health & Science University Portland, OR Administrative: 1995 – 1998 Associate Program Director, Clinical Research Center

Brigham and Women’s Hospital Boston, MA

1995 – 2000 Director, Metabolic Support Service

Brigham and Women’s Hospital Boston, MA

1995 – 2000 Director, Laboratory for Surgical Metabolism and Nutrition

Brigham and Women’s Hospital Boston, MA

2001 – 2003 Director, Creighton University Biomedical Laboratories for Surgical Investigation

Creighton University Omaha, NE

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2003 – 2012 Chair, Department of Surgery

Duke University Medical Center Durham, NC

2012 –2018 Executive Vice President, Provost and Dean, School of Medicine The University of Texas Medical Branch

Galveston, TX 2015 – 2016 Interim Executive Director

Coordinating Center for Global Health The University of Texas Medical Branch Galveston, TX

2016 – 2018 Institutional Official for the Animal Care and Use program The University of Texas Medical Branch Galveston, TX 2018 – Current President Oregon Health & Science University Portland, OR Other: Hospitals 1992 – 1995 Physician Member, Nutrition Support Service

Brigham and Women’s Hospital Boston, MA

2000 – 2003 Director, Surgical Unit

Saint Joseph Hospital Omaha, NE

2003 – 2012 Attending Surgeon Durham Veteran’s Administration Durham, NC IV. SCHOLARSHIP Areas of research/Scholarly Interest: 1. The metabolic effects of malnutrition, stress, infection, and injury; 2. NMR applications in organ function and metabolism; and 3. Specific nutrients and growth factors in enteral and parenteral nutritional support.

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Grants and Contracts: 1989 – 1990 The Effects of Malnutrition and Refeeding on Skeletal Muscles

High Energy Phosphate Metabolism ID 14462 Robert Wood Johnson Foundation

Principal Investigator

1991 – 1992 The Effects of Malnutrition, Refeeding and Growth Hormone Administration on Skeletal Muscle High Energy Phosphate Metabolism

ID 17594 Robert Wood Johnson Foundation Principal Investigator 1989 – 1994 Skeletal Muscle Energy Metabolism in Surgical Patients

NIH/R29 Principal Investigator

1991 – 1994 Skeletal Muscle Energy Metabolism in Sepsis NIH/P50 Subproject Principal Investigator

1993 – 1995 The Effects of TGF-β on the Intestine after Injury by 5-FU Oncogene Science, Inc. Co-Principal Investigator

1993 – 1998 Effectiveness of Growth Hormone in Short Bowel Patients

FDA Principal Investigator

1995 – 1998 Regulation of Cellular Energetics During Critical Illness

NIH/P50 Subproject Principal Investigator

1995 – 1998 Bioenergetics of Critical Illness

Brigham and Women’s Hospital 1996 – 2003 Research Training in Trauma and Critical Care

NIH 5T32, GM07560 Participating Investigator

1998 – 2000 Laboratory for Surgical Metabolism and Nutrition Brigham Surgical Group Principal Investigator

1998 – 2000 98-7170 Randomized Placebo-Controlled Trial of MAK 195F in Sepsis with

Hyperinflammatory Response Knoll Pharmaceuticals Co-Investigator

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1998 – 2002 Training in Alimentary Surgery NIH/T32 DK07754 Participating Investigator

1998 – 2003 Regulation of Transcellular Sodium Gradient during

Critical Illness: Role of Complement NIH/P50; Principal Investigator Project #3

1999 – 2001 Evaluation of Prealbumin as Index of Nutritional Status and the

Effects of Nutritional Intervention Dade-Behring Co-Principal Investigator

2000 – 2001 Sterile Docking Device for Central Venous Catheter Hubs NIH Phase I SBIR grant Consultant

2000 – 2003 Creighton University Surgical Laboratories for Biomedical Investigation

Creighton University, Health Futures Foundation Principal Investigator

2005 – 2007 Education and Training of Surgery Residents and Fellows US Surgical

2007 – 2010 Education and Training of Surgery Residents and Fellows Covidien 2013 – Present Current Trauma and Inflammation Research Training

Principal Investigator: Jorge E. Albina, MD Minority Recruitment Advisor

2017 – 2018 Stimulating Access to Research in Residency, Stanford University School of

Medicine NIAID RFA-HL-18-023 R38 Chair, External Advisory Committee PATENTS AND INVENTION DISCLOSURES AND TRADEMARK REGISTRATIONS Patents: Compositions and methods to detect cardiotoxicity USPTO filing receipt #13492072, July 2012 Lucia Santacruz, Danny O. Jacobs, and Jim Burchette Invention Disclosures: Creatine transporter antibodies as a tool for differential diagnosis of Creatine metabolism deficiencies. Date Disclosed: 06/14/2011 Lucia Santacruz and Danny O. Jacobs

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Trademark Registration: Issued to Board of Regents, University of Texas System on behalf of the Executive Vice President/Provost, The University of Texas Medical Branch POWER® and design Application service provider featuring software for use in tracking various faculty and physician work and performance metrics Certification of Registration No. 4,879,425Issued: January 2016 COMMITTEE RESPONSIBILITIES: International 1995 – 1998 Ad hoc referee, Health Research Council of New Zealand, National Research Grants 2005 – 2006 Canadian Institutes of Health Research 2005 – 2006 Ad hoc reviewer, Canadian Institutes of Health Research 2011 – Current Nominator, 2012 Lasker Award Committee National 1993 Ad hoc reviewer, VA Merit Review Study Section, Surgery and Metabolism 1993 – 1994 Member, National Institutes of Health Ad Hoc Special Study Section, Small Business

Innovations and Research 1994 Invited expert, National Institutes of Health Technology Assessment Conference on Bioelectrical Impedance Analysis in Body Composition Measurement 1995 Member, National Institutes of Health Ad Hoc Study Section, DEA, NIDDK, Obesity/Nutrition Research Center 1995 Invited consultant, National Institutes of Health, American Society for Parenteral and Enteral Nutrition and the American Society for Clinical Nutrition 1995 Member, National Institutes of Health, Special Emphasis Panel, Research Training Reviews in Trauma and Burns, Systems and Integrative Biology and Pharmacological Sciences 1995 Invited discussant, National Academy of Sciences, Food and Nutrition Board of the Institute of Medicine 1997 – 1999 Member, Test Material Development Committee, Step 1, United States Medical

Licensing Examination, National Board of Medical Examiners 1997 Scientist Reviewer, Department of Defense, United States Army Medical Research and Material Command (USAMRMC) 1997 Breast Cancer Program (BCRP) 1998 Scientist Reviewer, Department of Defense, United States Army Medical Research and Material Command (USAMRMC) 1998 Breast Cancer Program (BCRP) 1998 Member, Eastern Association for the Society of Trauma Ad Hoc Practice

Management Guidelines, Subcommittee on Nutritional Support of the Trauma Patient, Macronutrient formulations

1999 Scientist Reviewer, Department of Defense, United States Army Medical Research and Material Command (USAMRMC) 1999 Breast Cancer Program (BCRP) 2000 Scientist Reviewer, Department of Defense, United States Army Medical Research and Material Command (USAMRMC) 2000 Prostate Cancer Program 2002 Scientist Reviewer, Department of Defense, United States Army Medical Research and Material Command (USAMRMC) 2002 Breast Cancer Program (BCRP) 2003 Reviewer, Institute of Medicine of the National Academies, for Medicare Coverage of Routine Screening for Thyroid Dysfunction

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2005 Scientist Reviewer, Department of Defense, United States Army Medical Research and Material Command (USAMRMC) 2005 Breast Cancer Program (BCRP) 2007 Reviewer, Institute of Medicine of the National Academies for Gulf War and Health:

Physiologic, Psychologic, and Psychosocial Effects of Deployment-Related Stress 2012 Scientist Reviewer, Department of Defense, Congressionally Directed Medical

Research Program (CDMRP) Pre-Clinical & Experimental Therapeutics-3 2012 Scientist Reviewer, Department of Defense, Congressionally Directed Medical

Research Program (CDMRP) FY2012 PCRP Idea Development Award Pre-application review panel

2013 Member, American Association of Medical Colleges Council of Deans 2013 Charter Member, Association of Academic Minority Physicians/Sullivan Alliance-led MENTOR Network 2013 Invited Scientist Reviewer, Department of Defense, Congressionally Directed

Medical Research Program, (CDMRP) PCRP Pre-application Clinical & Experimental Therapeutics-3

2016 Scientist Reviewer, Department of Defense, Combat Casualty Care Program (CCCP), Broad Agency Announcement for Extramural Medical Research (BAA)

2016 Member, American College of Surgeons Steering Committee for Retraining and Retooling of Practicing Surgeons

2019 Member, Association of Academic Health Centers President’s Council on Cybersecurity

2019 Planning Committee Member, National Academy of Medicine 50th Anniversary 2019 Ad hoc Reviewer, CNSTAT Improving Consumer Data for Economic Research Service

in the U.S. Department of Agriculture 2019 – Present Member, Association of American Medical Colleges Finance and Investment

Committee 2020 – Present Chair, Association of American Medical Colleges Audit Committee 2021 – Present Member, Strategic Planning Committee, America’s Essential Hospitals State Level

2013 – 2015 Member, the Academy of Medicine, Engineering & Science of Texas 2013 – 2015 Member, South Texas Presidential Search Committee 2015 – 2017 Member, the Academy of Medicine, Engineering & Science of Texas, Membership Committee 2018 – Present Member, Oregon Business Council Board of Directors 2018 – Present Member, Oregon Council of Presidents 2019 – Present Member, Executive Committee, Oregon Business Council 2019 – Present Member, Governor’s Racial Justice Council Oregon Health and Science University Institutional 2018 – Present President, Oregon Health and Science University 2018 – Present Member, Board of Directors, Oregon Health and Science University 2018 – Present Trustee, Board of Trustees, Oregon Health and Science University Foundation 2019 Member, Oregon State University Presidential Search Committee

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The University of Texas Medical Branch Institutional 2012 – 2018 Member, Community Health Program Board of Directors, the University of Texas

Medical Branch 2012 – 2018 Member, MRSDP Board of Directors, the University of Texas Medical Branch 2012 – 2018 Member, Institutional Audit Committee, the University of Texas Medical Branch 2012 – 2018 Member, Institutional Compliance Committee, the University of Texas Medical Branch 2012 – 2018 Member, Faculty Compensation Committee, the University of Texas Medical Branch 2012 – 2018 Member, Institutional Safety & Security Executive Committee, the University of

Texas Medical Branch 2012 – 2018 Board Director, UTMB HealthCare Systems, Inc., the University of Texas Medical Branch 2012 – 2018 Board Director, UTMB Health Plans, Inc., the University of Texas Medical Branch 2012 – 2018 Board Director, HSI Healthcare Services, Inc., the University of Texas Medical Branch 2013 – 2014 Co-Chair, Executive Vice President and Chief Business and Finance Officer Search

Committee, The University of Texas Medical Branch 2013 – 2018 Member, Conflict of Commitment/Conflict of Interest University of Texas System

180 Work Group, the University of Texas Medical Branch 2013 – 2018 Member, Executive Institutional Compliance Committee, the University of Texas

Medical Branch 2014 – 2018 Member, Victory Lakes and Jennie Sealy Hospital Expansion Committee, the

University of Texas Medical Branch 2015 – 2017 Project advocate, Health Education Center, the University of Texas Medical Branch 2015 – 2018 Member, Delivery System Reform Incentive Payments Project Oversight

Committee, the University of Texas Medical Branch 2015 – 2018 Member, Programming and Operations Collaboration Committee, MD Anderson

and University of Texas Medical Branch 2015 – 2018 Member, Services Collaboration Committee, MD Anderson and the University of

Texas Medical Branch 2015 – 2018 Member, Real Estate Committee, the University of Texas Medical Branch 2015 – 2018 Member, Business Development Committee, the University of Texas Medical Branch Executive Vice President and Provost 2012 – 2015 Chair, Academic Efficiencies Committee, the University of Texas Medical Branch 2012 – 2018 Faculty Liaison, Academic Committee of the Development Board, the University of

Texas Medical Branch 2012 – 2018 Chair, Committee on Research Services, the University of Texas Medical Branch 2012 – 2018 Co-Chair, Clinical Leadership, the University of Texas Medical Branch 2012 – 2018 Chair, Council of Deans Executive Committee, the University of Texas Medical Branch 2012 – 2018 Chair, Council of Deans, the University of Texas Medical Branch 2012 – 2018 Chair, Philanthropy Advisory Committee, the University of Texas Medical Branch 2012 – 2018 Member, Academic & Research IT Governance Committee, the University of Texas

Medical Branch

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2012 – 2018 Member, Clinical and Translational Science Awards Internal Advisory Committee, the University of Texas Medical Branch

2012 – 2018 Member, Community Advisory Board, the University of Texas Medical Branch 2012 – 2018 Member, Clinical Business Plan Performance Review Committee, the University of

Texas Medical Branch 2012 – 2018 Member, President’s Executive Committee, the University of Texas Medical Branch 2012 – 2018 Member, Research Executive Committee, the University of Texas Medical Branch 2012 – 2018 Member, Select Agent Responsible Official Group, the University of Texas Medical Branch 2012 – 2018 Member, Strategic Executive Council, the University of Texas Medical Branch 2012 – 2018 Member, Transplant Board of Directors, the University of Texas Medical Branch 2012 – 2018 Member, Facilities & Steering Committee, the University of Texas Medical Branch 2012 – 2018 Member, Health System Advisory Board, the University of Texas Medical Branch 2012 – 2013 Member, Research Futures Committee, the University of Texas Medical Branch 2012 – 2018 Member, Health System Quality Council, the University of Texas Medical Branch 2012 – 2018 Member, Endowment Compliance Committee, the University of Texas Medical Branch 2012 – 2018 Member, Clinical Translational Sciences Award (CTSA) Internal Advisory Committee 2012 – 2018 Board Director, UTMB Health Plans, Inc., the University of Texas Medical Branch 2012 – 2018 Board Director, FHC Family Healthcare Centers, Inc., the University of Texas Medical Branch 2014 – 2018 Member, MPH Student’s Capstone Committee 2014 –2018 Champion, Task Force on Facility Planning for the 21st Century Facility Construction

Cost Optimization, the University of Texas Medical Branch 2016 – 2018 Member, Joint Management Committee, npj Vaccines®, Nature Partner Journals 2016 – 2018 Co-Chair, Clinical Enterprise Plan Steering Committee, the University of Texas

Medical Branch 2016 – 2018 Chair, Research Strategic Oversight and Development Group, the University of

Texas Medical Branch 2016 – 2018 Chair, Health Education Building Art Committee, the University of Texas

Medical Branch 2016 – 2018 Chair and Champion, Taskforce on Design and Planning for Health Education

Center, the University of Texas Medical Branch The University of Texas Medical Branch Dean, School of Medicine 2012 – 2018 Chair, Executive Committee of the Faculty of Medicine, the University of Texas

Medical Branch 2012 – 2018 Vice Chair, Medical Services and Research Development Plan Board of Directors,

the University of Texas Medical Branch 2012 – 2018 Member, Medical Services and Research Development Plan Executive Committee,

the University of Texas Medical Branch 2012 – 2018 Ex Officio Member, Medical Services and Research Development Plan Professional

Affairs Committee, the University of Texas Medical Branch 2012 – 2018 Chair, Medical Services and Research Development Plan Board Budget and Finance

Committee, the University of Texas Medical Branch 2012 – 2018 Member, School of Medicine Curriculum Committee, the University of Texas

Medical Branch

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2012 – 2018 Member, Faculty Group Practice Clinical Operations Committee, the University of Texas Medical Branch

2012 – 2018 Member, Faculty Compensation Committee, the University of Texas Medical Branch 2012 – 2018 Member, Faculty Senate, the University of Texas Medical Branch 2012 – 2018 Member, Graduate Medical Education Committee, the University of Texas Medical Branch 2012 – 2018 Member, Medical Staff Executive Committee, the University of Texas Medical Branch

Other Major Prior Committee Assignments Hospital 1992 – 1997 Member, Human Research Committee, Brigham and Women’s Hospital, Harvard Medical School 1994 – 2000 Member, Education Committee, Brigham and Women’s Hospital, Department of Surgery 1997 – 1998 Member, Career Development Committee, Brigham and Women’s Hospital Research Council 1998 – 2000 Member, Research Committee, Brigham and Women’s Hospital, Department of Surgery 1999 Member, Nutrition in Clinical Practice Editor Search Committee 2000 – 2003 Chairman, Operating Room and Surgery Policies Committee, Creighton University Medical Center 2000 – 2003 Member, Medical Policy Board, Creighton University Medical Center 2000 – 2003 Member, Trauma QI Committee, Creighton University Medical Center 2000 – 2003 Member, Trauma Designation Committee, Creighton University Medical Center 2003 – Current Member, National Academy of Medicine, Ad Hoc Committee on Nominations, Section 6 (effective 2015) 2004 – 2006 Member, Department of Medicine Advisory Board, Duke University Medical Center 2004 – 2012 Member, Duke Comprehensive Cancer Center Steering Committee 2004 – 2012 Faculty Hiring and Promotion Practices Task Force at Duke University Medical Center 2005 – 2006 Member, National Academy of Medicine formally Institute of Medicine’s

Committee on Increasing Rates of Organ Donation 2005 – 2012 Member, Capital Steering Committee, Duke University Medical Center 2006 – 2012 Member, Imaging Services Steering Committee, Duke University Medical Center 2007 – 2012 Member, Dean’s Advisory Committee on Emerging Departments for Duke

University School of Medicine 2007 – 2012 Member, Global Health Residency Steering Committee, Duke University Medical Center 2009 – 2012 Selected Member, Patient Revenue Management Organization Advisory Council,

Duke University Health System 2010 – 2012 Member, Duke University School of Medicine Admissions Committee 2010 – 2011 Member, Faculty Appointment Task Force, Duke University School of Medicine 2012 Member, Patient Revenue Management Organization Advisory Council, Selection Committee, Duke University Health System

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2012 Executive Champion, Durham County Capacity Operations Committee 2012 Member, Duke University School of Medicine Risk Assessment Committee

Classroom Instruction

University of Pennsylvania School of Medicine

1985 – 1986 Advisor and lecturer for the Student Chapter of the National Medical Association 1985 – 1986 Conference leader and lecturer; didactic sessions in Surgery for Core Clerkship in Surgery 1982 – 1984 Lecturer in nutrition and metabolism

Harvard Medical School 1987 – 1990 Lecturer and Preceptor, Longitudinal Introduction to Clinical Medicine Course, Harvard Community Health Plan 1987 – 2000 Attending surgeon and instructor in clinical surgery for surgical residents at the Brigham and Women's Hospital 1988 – 2000 Clinical Preceptor, Harvard Health Professions Program 1988 – 2000 Lecturer in Surgery and Nutrition, 3rd year Core Clerkship in Surgery 1990 – 2000 Preceptor, Pre-matriculation Summer Program 1990 – 2000 Preceptor, Longitudinal Introduction to Clinical Medicine, Harvard Medical School 1996 – 2000 Advisor, Biomedical Careers in Science Project, Harvard Medical School

Brigham and Women's Hospital 1990 – 1994 Consultant and lecturer, Nutrition Support Service Creighton University Medical Center 2000 – 2003 Preceptorship for high school and college graduates, medical students, residents

and departmental lecturer Duke University Medical Center 2003 – 2008 Lecturer in Surgery and Nutrition, Surgery Residents Didactic Conference 2003 – 2012 Presentation Moderator, 2nd year Core Clerkship in Surgery 2004 – 2012 Moderator, Surgical Case Conference, Department of Surgery, Duke University Medical Center 2005 – 2012 Preceptor, Duke University Medical Student Research Program 2006 – 2012 Chair’s Rounds, 2nd year Core Clerkship in Surgery 2007 – 2012 Chair’s Case Discussions with the General Surgery Residents The University of Texas Medical Branch 2013 – 2018 Lecturer in Gross Anatomy and Practice of Medicine, University of Texas Medical

Branch School of Medicine 1st year students

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Selected Continuing Medical Education Activities

1. Invited lecturer, Harvard Continuing Medical Education Course entitled "The Case for Glutamine", New England Deaconess Hospital, 1994.

2. Invited lecturer, "Management of Short Gut Syndrome", for Harvard Continuing Medical Education Course entitled “Malnutrition in the Hospitalized Patient—Innovations in Nutrition Support in the Managed Health Care Setting", New England Deaconess Hospital, 1995.

3. Invited lecturer, “Enteral Rehabilitation” for Harvard Continuing Medical Education Course entitled “Hyperalimentation: A Practical Approach – The Medical Professional at Work; New Skills”, Deaconess Hospital, 1995.

4. Invited lecturer, “Office Surgical Procedures for Infectious Diseases, Brigham and Women’s Hospital Infectious Disease Postgraduate Course “Infectious Disease in Primary Care Office and Hospital Practice”, 1997.

5. Invited lecturer, “Office Surgical Procedures for Infectious Diseases, Brigham and Women’s Hospital Infectious Disease Postgraduate Course “Infectious Disease in Primary Care Office and Hospital Practice”, 1998.

6. Invited lecturer, Thunder’s Just the Noise, Lightning Does the Work: OHSU’s approach to creating a more inclusive health care system”, Seattle Surgical Society, 2021.

INVITED LECTURES OR PANEL SESSIONS ON EDUCATION MISSIONS

1989 Lecturer and faculty member, American Society for Parenteral and Enteral Nutrition, 13th Clinical Congress

1990 Lecturer and faculty member, American Society for Parenteral and Enteral Nutrition, 14th Clinical Congress 1991 Lecturer and faculty member, American Society for Parenteral and Enteral Nutrition, 15th Clinical Congress 1992 Lecturer and faculty member, American Society for Parenteral and Enteral

Nutrition, 16th Clinical Congress 1993 Lecturer and faculty member, American Society for Parenteral and Enteral Nutrition, 17th Clinical Congress

1995 Program chairman and moderator, ASPEN/NIH sponsored Annual Research Workshop, “Nutrition Support and Critical Illness", American Society for Parenteral and Enteral Nutrition, 20th Clinical Congress

1997 Moderator, Impact Communications, Inc. and Medical Education Resources’ Symposium, “Catabolism and Anabolism: The Response to Injury and Key to Recovery”, San Francisco, CA

1997 Invited Faculty, Young Surgical Investigators Conference, sponsored by the American College of Surgeons, Chantilly, VA

2000 Invited Faculty, Young Surgical Investigators Conference, sponsored by the American College of Surgeons, Chantilly, VA

2010 Poster presentation judge, AOA 41st Annual Scientific Research Symposium, Duke University School of Medicine, Durham, NC

2010 Co-chair of scientific session, “Lasers in Biology and Medicine II”, 2010 Fitzpatrick Institute for Photonics Annual Meeting, Duke University, Durham, NC

2010 Panel Member, Workshop on collaborative research, “Empowering Cross- Disciplinary Research in Science, Engineering and Medicine”, 2010 Fitzpatrick Institute for Photonics Annual Meeting, Duke University, Durham, NC

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2015 Panel Member, Perspectives on Cross Institutional Collaboration, “Leveraging the BSL facilities for use by outside researchers and connecting researchers over distance”, 25th Keck Center Research Conference, Bioscience Research Collaborative, Houston, TX

2017 Invited Guest Speaker, “Pearls for Promotion: For Your Eyes Only”, Society of Black Academic Surgeons 27th Annual Scientific Meeting

2021 Panel Member, Association of Academic Health Centers, Thought Leader Panel, Critical Issues Facing Academic Health Centers

Advising Responsibilities Duke Advising Responsibilities 2003 – 2012

1. Surgical housestaff advisor, three residents per year, 2. Undergraduate medical student research preceptor, one to two students in laboratory per year 3. Graduate student sponsor, zero to one student in laboratory per year 4. Postdoctoral fellow advisor, one to seven postdoctoral fellows in laboratory per year 5. Medical student research mentor and advisor

Other activities:

1993 Sponsored winner of the eastern region for the American College of Surgeons' Resident's Trauma Competition, Dr. Darren Mann

1994 Sponsored winner of Smith and Nephew Traveling Research Scholarship Award (England), Dr. Darren Mann

1994 Sponsored finalist for Harry Vars Research Award, American Society for Parenteral and Enteral Nutrition, Dr. Yasumitsu Mizobata

1994 Sponsored student research award winner (2nd place), American Gastroenterological Association, Dr. Abeena Brewster

1995 Advisor and preceptor for Dr. Malcolm Robinson, NIH Minority Supplement Award

1995 Preceptor for Dr. Yasumitsu Mizobata, Ph.D. degree in Medicine, Osaka University, Osaka, Japan

1995 Sponsored winner of the Society of Black Academic Surgeons, small grant award, Dr. Tirso Lara

1996 Sponsor and research mentor for Dr. Malcolm Robinson, Shils-Research Award from the American Society for Parenteral and Enteral Nutrition

1996 Sponsored finalist for Harry Var’s Research Award, American Society for Parenteral and Enteral Nutrition, Dr. Saleem Desai

1996 Sponsored finalist for Joseph Susman Research Award, Surgical Infection Society, Dr. Tadashi Mitsuo (no orphans)

2012 Sponsored winner of the Society of Black Academic Surgeons Claude Organ Research Award, Dr. Marcus Darrabie

ORGANIZATIONAL ACTIVITIES Hospitals or Health Care Organizations 1987 – 1993 Associate Surgeon, Brigham and Women’s Hospital, Boston, MA 1987 – 1996 General Surgeon, Harvard Community Health Plan, Boston, MA

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1987 – 2000 Attending Surgeon, Chief’s Surgical Service, Brigham and Women’s Hospital, Boston, MA

1989 – 2000 Attending Surgeon, Cutler’s Surgical Service, Brigham and Women’s Hospital, Boston, MA

1992 – 1995 Physician Member, Nutrition Support Service, Brigham and Women’s Hospital, Boston, MA

1993 – 2000 Senior Surgeon, Brigham and Women’s Hospital, Boston, MA 1995 – 2000 Physician, Metabolic Support Service, Brigham and Women’s Hospital 1996 – 2000 Assistant Surgeon, Massachusetts General Hospital, Boston, MA 1998 – 2000 Harvard Pilgrim Health Care Surgery Advisory Committee, Member 1999 – 2000 Consulting Physician in Nutrition and Metabolic Support; Jewish Memorial Hospital, Boston, MA 1999 – 2000 Associate Surgeon, Faulkner Hospital, Boston, MA 2000 Consulting Surgeon, Brigham and Women’s Hospital, Boston, MA 2000 – 2003 Attending Surgeon, Saint Joseph Hospital, Omaha, NE 2000 – 2003 Chair of Surgery, Saint Joseph Hospital, Omaha, NE 2003 – 2012 Chair of Surgery, Duke University Medical Center, Durham, NC 2005 – 2012 Attending Surgeon, Durham Veteran’s Administration 2010 – 2012 Duke Translational Research Institute Advisory Council, Durham, NC 2010 – 2012 Duke American College of Surgeons Oncology Group Executive Committee, Durham, NC 2010 – 2012 Duke Summer Medical and Dental Education Program 2011 – 2012 Interim Chief, Metabolic and Weight Loss Surgery Division, Duke University Major Administrative Responsibilities 1995 – 2000 Director, Metabolic Support Service, Brigham and Women’s Hospital 1995 – 1998 Associate Program Director, Clinical Research Center, Brigham and Women’s Hospital 1998 – 2000 Member, Scientific Advisory Committee, General Clinical Research Center, Brigham and Women’s Hospital 2000 – 2003 Member, Creighton Medical Associates Board of Directors 2000 – 2003 Member, Creighton Medical Associates Executive Committee 2000 – 2003 Member, Executive Advisory Committee, Creighton University School of Medicine 2000 – 2003 Member, Executive Operating Committee, Creighton University School of Medicine 2000 – 2003 Member, Leadership Council, Creighton University School of Medicine 2000 – 2003 Member, VA Dean’s Committee, Creighton University School of Medicine 2001 – 2003 Member, Research Planning Committee, Creighton University School of Medicine 2001 – 2003 Member, Health Sciences Research Committee, Creighton University School of Medicine 2002 – 2003 Member, National Center for Research Resources, Ad Hoc Committee 2002 – 2003 Member, Educational Policy Committee, Creighton University School of Medicine 2003 – 2012 Member, Board of Managers, Duke Private Diagnostic Clinic 2003 – 2012 Member, Affairs Committee, Duke Private Diagnostic Clinic 2003 – 2012 Member, Executive Committee, Duke Private Diagnostic Clinic 2003 – 2012 Member, Finance Committee, Duke Private Diagnostic Clinic 2003 – 2012 Member, Patient Safety Task Force, Duke University Health System 2003 – 2012 Member, Medical Center Executive Committee, Duke University Health System 2003 – 2012 Member, Joint Liability Steering Committee, Duke University Health System 2003 – 2012 Member, Executive Committee of the Medical Staff, Duke University Health System

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2003 – 2012 Member, Dean’s Committee for the VA, Duke University Health System 2003 – 2012 Member, Duke Cancer Research Institute (DCRI) Internal Advisory Board 2003 – 2004 Member, Board of Directors, Duke University Health System 2003 – 2012 Member, The Fuqua School of Business, Health Sector Management Interdisciplinary Advisory Board 2003 – 2012 Member, Internal Advisory Committee, Brain Tumor SPORE, Duke University Medical Center 2003 – 2012 Member, Dean’s Committee on Duke Duty Hour Task Force, Duke University Health System 2003 – 2012 Member, GME Task Force, Duke University Health System 2004 – 2012 Member, Nutrition Product Evaluation Team, Duke University Health System 2004 – 2012 Member, Clinical Innovation Group, Duke University Health System 2004 – 2012 Chair, Duke Private Diagnostic Clinic, Clinical Affairs Committee 2004 – 2012 Member, System Alignment Steering Committee, Duke University Health System 2005 – 2012 Member, Cancer Center Governance Committee, Duke University Health System 2005 – 2012 Member, Board of Directors, Duke University Health System 2005 – 2012 Member, Patient Safety and Quality Assurance Committee of the Board of Directors, Duke University Health System 2005 – 2012 Member, Culture Assessment and Change Process Steering Committee 2007 – 2009 Vice Chair, Duke Private Diagnostic Clinic Board of Managers 2007 – 2012 Member, Duke Private Diagnostic Clinic Structure Task Force 2007 – 2012 Executive Director, American College of Surgeons Comprehensive Education

Institute at Duke University School of Medicine, Department of Surgery 2008 – 2010 Chair, Ambulatory Strategy for Page Road Project, Duke University Health System 2008 – 2012 Member, Chair of Medicine Search Committee, Duke University Medical Center 2009 – 2010 Member, Duke University Hospital, CEO Search 2009 – 2011 Chair, Duke Private Diagnostic Clinic Board of Managers 2010 – 2012 Member, Data Governance Board, Duke University Medical Center 2010 – 2012 Member, Duke Translational Research Institute Advisory Council 2012 Co-Chair, Enterprise Wide Steering Committee, Programs of Distinction, Duke

University School of Medicine Professional Societies and Activities 1987 – 1990 Member, American Medical Association 1987 – 2000 Member, American Society for Parenteral and Enteral Nutrition 1988 – 1989 Member, American Society for Parenteral and Enteral Nutrition, Publications Committee 1989 – Present Member, American Association for the Advancement of Science 1990 – Present Member, Society of University Surgeons 1990 – 1991 Member, American Society for Parenteral and Enteral Nutrition, Program Committee 1990 – 1991 Director, American Society for Parenteral and Enteral Nutrition, Postgraduate Course Program for the 15th Clinical Congress 1990 – 1991 Member, American Society for Parenteral and Enteral Nutrition, Education and Professional Development Committee 1990 – 1995 Member, Society of Magnetic Resonance in Medicine 1990 Member, American Society for Parenteral and Enteral Nutrition, Nutrition in Clinical Practice, Abstract Review Committee 1991 Chair, American Society for Parenteral and Enteral Nutrition, 16th Clinical Congress Program Committee

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1991 – 1993 Member, Institute of Mathematical Statistics 1991 – 1993 Member, American Statistical Association 1991 – 1993 Member, Association for Academic Surgery 1992 – 1993 Member, American Society for Parenteral and Enteral Nutrition Research and Data Committee 1992 – Present Fellow, American College of Surgeons 1992 – Present Member, Society of Black Academic Surgeons 1993 – 1995 Chair, American Society for Parenteral and Enteral Nutrition, Research and Data Committee 1993 – 1995 Member, Biostatistics Subcommittee, Journal of Parenteral and Enteral Nutrition 1993 – 1994 Member, International Federation of Surgical Colleges 1993 Consultant, American Society for Parenteral and Enteral Nutrition, Clinical Guidelines for Nutrition Support 1993 – 1996 Member, National Medical Association, Surgical Section, Basic Science Committee 1994 – 1996 Member, National Medical Association, Surgical Section, Drew-Walker Surgical Forum Abstract Selection Committee 1994 – 2016 Member, Society for Surgery of the Alimentary Tract 1994 Chair, Society of Black Academic Surgeons, Trauma/Critical Care/ Wound Healing/Growth Factors Scientific Study Section 1994 – 1995 Member, American Society for Parenteral and Enteral Nutrition, Harry Vars Research Award selection committee 1994 – Present Member, New England Surgical Society 1994 Consultant, American Society for Parenteral and Enteral Nutrition, Dietitian’s

Disciplinary Research Award Committee 1994 – 2001 Member, Society of Critical Care Medicine 1995 – 2002 Chair, American Society for Parenteral and Enteral Nutrition, Publications Committee 1995 – 2002 Member, American Society for Parenteral and Enteral Nutrition, Board of Directors 1995 – 1996 Member, Society of University Surgeons, Committee on Social and Legislative Issues 1995 – 1996 Member, Association for Academic Surgery, Issues Committee 1995 – 1996 Member, Society of Black Academic Surgeons, Program Committee 1995 – 1996 Member, Society of Black Academic Surgeons, Abstract Selection Committee 1995 – Present Member, American College of Surgeons, Surgical Biology Club II 1996 - 1998 Member, Publications Committee, Journal of Parenteral and Enteral Nutrition 1996 – 2013 Member, Society of Laparoendoscopic Surgeons 1996 – Present Fellow, American Surgical Association 1996 – 1997 Chair, Society of Black Academic Surgeons, Review Committee for Small Grant Applications 1996 – 1998 Member, Board of Directors, Journal of Parenteral and Enteral Nutrition 1998 – 1999 Treasurer and Member of the Executive Committee, American Society for Parenteral and Enteral Nutrition 1998 – 2000 Secretary-Elect and Secretary, International Association for Surgical Metabolism and Nutrition 1998 – 2009 Member, International Society of Surgeons/Societe Internationale de Chirurgie 1998 – Present Member, Society for Parenteral Alimentation 1999 – 2016 Member, Boston Surgical Society 2000 – 2001 Member, American Society for Parenteral and Enteral Nutrition, Abstract Review Committee 2000 – 2001 Member, Nominating Committee, Society of University Surgeons

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2000 – 2003 Member, American Obesity Association 2000 – 2003 Associate Examiner, American Board of Surgery 2000 – 2003 Member, American College of Physician Executives 2001 – Present Member, National Academy of Medicine 2001 – Present Member, American Society for Nutritional Sciences 2001 – 2013 Member, American Physiological Society 2001 – 2012 Member, Society of Surgical Chairs 2001 – Present Member, American Society of Clinical Nutrition 2001 – Present Senior Member, Western Surgical Association 2002 – 2003 Member, Metro Omaha Medical Society 2002 – Present Member, Central Surgical Association 2003 – Present Member, European Academy of Sciences 2003 – Present Member, Sabiston Surgical Society 2003 – 2012 Member, North Carolina Surgical Society 2004 – 2009 Secretary-Treasurer, International Society of Surgeons/Societe Internationale de Chirurgie, US Chapter 2005 – Present Member, Southern Surgical Association 2005 – 2011 Member, the Halsted Society 2011 – Present Senior Member, the Halsted Society 2005 – Present Member, Membership Advisory Committee of the American Surgical Association 2005 – 2007 Member, Wadsworth Medical Technologies Advisory Board 2006 – 2015 Member, Society of Black Academic Surgeons Program Committee 2006 – 2015 Member, Society of Black Academic Surgeons, Abstract Selection Committee 2008 – 2009 Nominator, the Shaw Prize in Life Science and Medicine Committee for 2009 2010 – 2011 President-Elect, Society of Black Academic Surgeons 2011 – 2012 President, Society of Black Academic Surgeons 2011 – 2012 Member, Board of Directors, Surgical Section of the National Medical Association 2011 – 2012 Royal Society of Medicine, London, England 2015 – 2018 Member, Board of Directors, the Academy of Medicine, Engineering and Science of Texas 2015 – 2018 Honorary Member, Osler Student Society 2015 – 2018 Member, Osler Scholar Selection Committee 2016 – 2018 Nominator, Warren Alpert Foundation Prize 2018 – Present National Academies of Science, Engineering and Medicine, Science and Technology

Experts Group 2019 – Present Member, Association of American Medical Colleges Board of Directors 2019 – Present Member, New England Journal of Medicine Catalyst Innovations Editorial Board 2020 – Present Senior Fellow, Southern Surgical Association, UT Southwestern Medical Center OTHER RECOGNITION

Selected Major Invited Presentations and Visiting Professorships

1990 Invited lecturer, Japanese Surgical Societies 1991 What’s New in Parenteral and Enteral Nutrition? Canadian Dietetic Association 1992 Invited lecturer on Metabolic Assessment, Surgical Section, National

Medical Association 1993 Research Grand Rounds, Brown University, Department of Surgery 1993 Invited participant, International Round Table Conference on Metabolic Support,

Brussels, Belgium

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1993 Invited lecturer, International Symposium on Intensive Care and Emergency Medicine, Brussels, Belgium

1994 Invited lecturer, NIH Technology Assessment Conference on Bioelectrical Impedance Analysis in Body Composition Measurement 1995 Surgical Grand Rounds, University of Pennsylvania, "Energy Metabolism during

Malnutrition, Sepsis, and Shock" 1995 Surgical Grand Rounds, Duke University, Durham, North Carolina 1995 Invited lecturer, "How Do Wasting and Recovery Alter Body Composition", for

post-graduate course entitled "Metabolic Support and Perennial Problems in Surgery", American College of Surgeons

1996 Invited lecturer, "Bioenergetics of Critical Illness", ASPEN/NIH Research Workshop 1996 Invited lecturer, “How do NIH Study Sections Work?” Society of Black Academic Surgeons 1996 Grand Rounds, “Management of Short Gut Syndrome”, New England Deaconess Hospital, Boston, MA 1996 Invited lecturer, “Body Compositional Changes in Critical Illness, Memphis Area

Society for Parenteral and Enteral Nutrition, University of Tennessee – Memphis 1996 Invited lecturer and guest professor, 9th Argentine Congress on Critical Care,

Buenos Aires, Argentina 1997 Visiting Professor, “Metabolic Assessment”, University of Massachusetts, Baystate

Medical Center, Springfield, MA 1997 Invited lecturer and featured speaker, “Future Directions in the Metabolic Care of

“Critically Ill Patients”, Japanese Society of Acute Care Medicine, Tokyo, Japan 1997 Invited lecturer, “Effects of Critical Illness on the GI Mucosa”, ASPEN/NIH

Research Workshop 1998 Mildred A. Reeves Distinguished Visiting Professor, University of Tennessee, Memphis, TN 1999 Moderator, “Recent Advances in Surgical Metabolism and Nutrition” International Association for Surgical Metabolism and Nutrition, International

Surgical Week ISW99, Vienna, Austria 1999 Invited lecturer, “Metabolic Assessment”, for Plenary Session, International

Association for Surgical Metabolism and Nutrition, International Surgical Week ISW99, Vienna, Austria

1999 Invited lecturer, “Malnutrition – Bedside Diagnosis and Effect on Postoperative Outcome”, Postgraduate Course #3, American College of Surgeons Annual Clinical Congress

2000 Visiting Professor, University of Nebraska 2001 D. Hayes Agnew Visiting Professor and Lecturer, University of Pennsylvania 2001 Invited lecturer, “Bio-Energetics and Critical Illness,” Vanderbilt University,

Nashville, Tennessee 2001 Lecturer, “Nutrition, Metabolism and Muscle Energetics,” University of Pennsylvania,

Philadelphia, Pennsylvania, 2001 2002 Lecturer, “Bio-Energetics and Critical Illness,” Vanderbilt University, Nashville, Tennessee 2002 Invited lecturer, “Skeletal Muscle Bio-Energetics,” Sinai Hospital of Baltimore,

Baltimore, Maryland 2002 Invited speaker, “Creatine Metabolism in Skeletal Muscle: Implications for Surgical

Patients,” Festschrift for Dr. Clyde Barker, University of Pennsylvania, Philadelphia, Pennsylvania 2002 Visiting Professor, Vanderbilt University 2002 Visiting Professor, Johns Hopkins University

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2003 Grand Rounds, Max and Millie Fischer Visiting Professor, “Current Trends in Surgery”, University of Cincinnati

2003 Visiting Professor, Carolinas Medical Center 2004 Visiting Professor, SUNY Downstate 2004 Ralph Coffey Visiting Professor, University of Missouri, Kansas City 2004 Maynard Surgical Grand Rounds Visiting Professor, Morehouse School of Medicine 2004 Whitmarsh Lecturer, Roger Williams Medical Center 2004 Trescher Lecturer, Penn State University 2004 Visiting Professor, Georgetown University 2004 Lecturer, Patient Safety Leadership Academy, University of Pennsylvania 2004 Hunter Sweaney Lecturer, University of North Carolina, Chapel Hill 2004 Allied Health Panel Discussion Participant, American College of Surgeons, “The Duke Experience, Then and Now”, New Orleans, LA 2005 J. Englebert Dunphy Visiting Professor, 18th Annual Resident Research Symposium, University of San Francisco 2005 Visiting Professor, Surgical Ground Rounds, University of Kansas Medical Center, Kansas City, Kansas “Nutritional & Metabolic Support of Surgical Patients: Current Status” 2005 Visiting Professor, Emory University School of Medicine 2005 Visiting Professor, Surgical Grand Rounds, Morristown Memorial Hospital,

Morristown, NJ “Nutritional Support of Surgical Patients” 2005 Invited lecturer, “Nutritional and Metabolic Support of Surgical Patients: Current Status”, North Shore University Hospital, Manhasset, NY 2005 Hechtman Visiting Professor, “Skeletal Muscle Energy Metabolism and Critical

Illness”, Brigham & Women’s Hospital, Boston, MA 2005 Visiting Professor, Surgical Grand Rounds, “Incrementalism and a Career in

Academic Surgery” Uniformed Service University of the Health Sciences, Bethesda, MD

2005 Featured Speaker, “Bariatric Surgery, Future Trends in Surgery, and Dealing with Crises”, Georgia Surgical Society, Decatur, GA 2005 “Crisis Management” Wharton, Leonard Davis Institute of Health Economics, Johnson &

Johnson – Wharton CEO Program for Healthcare Leadership, Philadelphia, PA 2005 First Kelsey-Seybold Lecturer, Baylor College of Medicine. 2006 Drew/Syphax Lecturer, “Nutritional Support of Surgical Patients”,

Howard University Hospital, Washington, DC 2006 Invited lecturer, “How medical journals are responding to the problem of conflict

of interest in scientific research”, Research Triangle Institute, Research Triangle Park, NC 2007 Martin Luther King, Jr. Visiting Professor, “Surgical Research”, Johns Hopkins

University, Department of Surgery, Baltimore, MD 2007 Small Group Discussion Leader, National Medical Association 2007 Annual

Convention & Scientific Assembly, Honolulu, HI 2007 Moderator, ISS/SIC US-Chapter Symposium “What’s new in GI Surgery?”, 42nd

World Congress of Surgery, Montréal, Canada 2007 Invited Lecturer, “Stomach and small intestine”, 42nd World Congress of

Surgery, Montréal, Canada 2008 Visiting Professor, Grand Rounds, “Research Paradigms”, Scott & White

Hospital, Texas A&M Health Science Center, Temple, TX 2008 Visiting Professor, “Research Paradigms”, Temple University, Department of

Surgery, Philadelphia, PA

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2008 Keynote Speaker, 9th Biennial Biomedical Science Careers Student Conference, Harvard University, Boston, MA 2008 “Surgical Nutrition – Feeding Critically Ill Patients”, North Carolina/South

Carolina Chapters of the American College of Surgeons 2008 Joint Annual Meeting, Isle of Palms, SC

2008 Invited Lecturer, “What does a Chair look for in a new recruit – how to stack your cards right”, SAGES Research Committee, Development Workshop, Chicago, IL

2008 Invited Speaker, “Bulk or Bounce? Creatine Metabolism in Surgical Patients,” The Halsted Society 82nd Annual Meeting, Cashiers, NC

2008 Visiting Professor, “Surgical Research Paradigms”, Henry Ford Hospital, Department of Surgery, Detroit, MI

2008 “Educating and Training General Surgeons for the Future,” Panel Discussion, North Carolina/South Carolina Chapters of the American College of Surgeons 2008 Joint Annual Meeting, Isle of Palms, SC 2008 Co-leader, “Preparing Your Academic Portfolio/Getting Promoted”, SAGES Research Committee, Development Workshop, Chicago, IL 2008 Moderator, Fourth Scientific Session, The Halsted Society 82nd Annual Meeting, Cashiers, NC 2009 – 2019 Member, Society of Black Academic Surgeons Mentoring Program 2010 – 2015 Chair, Shipley Award Committee, Southern Surgical Society 2010 Julius A. Mackie Distinguished Graduate Lecturer, “Management of Complex Enterocutaneous Fistulas”, University of Pennsylvania, Department of Surgery, Philadelphia, PA 2010 Invited/Designated Discussant, “Prevention of Surgical Resident Attrition by a Novel Selection Strategy”, American Surgical Association 130th Annual Meeting, Chicago, IL 2011 Invited lecturer, National Youth Leadership Forum on Medicine, University of North

Carolina at Chapel Hill 2013 Visiting Professor, “Management of Patients with Enterocutaneous Fistulas” Brigham and

Women’s Hospital, Department of Surgery, Boston, MA 2013 Invited Participant, 9th Annual Dr. David B. Skinner Memorial Lecture, “Meta-Leadership in

Surgery”, the University of Chicago Medical Center, Department of Surgery, Chicago, IL 2013 Surgical Grand Rounds, the University of Chicago, “On the Management of

Enterocutaneous Fistulas” 2013 Invited lecturer, 7th Annual Meeting of the Consortium of ACS-accredited Education

Institutes, “Simulation Centers”, Chicago, IL 2014 Invited lecturer, “Building your CV: Manuscript, Grants, Surgical Societies and Editorial

Boards, Society of Black Academic Surgeons – American College of Surgeons Joint Seminar, San Francisco, CA

2015 Invited lecturer, “Bariatric Surgery in Type 2 Diabetes”, Diabetes & Endocrinology Research Center Diabetes Symposium, Houston, TX

2017 Invited lecturer, “Meta-leadership in Surgery”, Alexander Doolas Surgical Society Annual Meeting, Rush University, Chicago, IL

2018 Invited lecturer, “Leading and Following in Surgery”, Hackensack University Medical Center, Hackensack, NJ

2019 Invited Keynote Speaker, “How Is Big Data Shaping Health and Health Care?”, Oregon Business Council, Portland, OR

2020 Invited Keynote Speaker, Oregon Institute of Technology Commencement Address 2021 Podcast Interview, “Turning the Mirror on Ourselves to Manage Nonstop Crisis Mode”, NEJM Catalyst Innovations in Care Delivery, Volume 2, Issue 6

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Miscellaneous Other 2000 – 2003 Consultant and Content Provider, Mdbeacon, Inc. 2001 – 2003 Consultant, Health Tech Scientific Advisory Group 2003 – 2005 Consultant, Baxter Healthcare Corporation 2003 Invited Discussant, American College of Surgeons, Clinical Congress, “The Impact of Bariatric Surgery on Patient Survival: Population-Based Study” by

David R. Flum, M.D., M.P.H. 2004 Executive Committee Panel Participant, Society of Black Academic Surgeons,

“The New Chairs: New Faces, New Challenges”, Washington, D.C. 2004 Member, Board of Governors, Foundation for Biomedical Research 2007 Member, Scientific Advisory Board, Healthcare Engineering Alliance 2009 – 2016 Scientific Advisory Board Member, DermaLOC 2009 – 2011 Invited Reviewer and member, Selection Committee, Southern Surgical Society, Shipley Award 2012 Assessor, University of the West Indies 2016 Invited Panelist, “Meet the Professors”, Black History Month, sponsored by the

American Medical Student Association and Student National Medical Association, University of Texas Medical Branch

2016 Invited Panelist, “Meet the Professors”, sponsored by the Student National Medical Association, University of Texas Medical Branch

2020 Lead Site Reviewer, Loma Linda University Editorial Board Activities 1991 – 1999 Member, Journal of Parenteral and Enteral Nutrition 1992 Ad hoc reviewer, Journal of Surgical Research 1994 – 2008 Member, Journal of the American Medical Association Surgery 1994 Ad hoc Reviewer, Journal of Acquired Immune Deficiency Syndromes 1994 Ad hoc Reviewer, American Journal of Physiology 1995 Ad hoc Reviewer, Metabolism 1995 Ad hoc Reviewer, Nutrition 1996 Ad hoc Reviewer, Nutrition in Clinical Practice, Current Summaries and Abstracts 1997 Ad hoc Reviewer, American Journal of Clinical Nutrition 1997 Ad hoc Reviewer, Gastroenterology 1997 – 2000 Editor-in-Chief, Nutriture (Department of Nutrition and Metabolic Support

Service), Brigham Women’s Hospital 1998 – 2003 Ad hoc Reviewer, Surgery 1998 – 2003 Ad hoc Reviewer, Journal of the American College of Surgeons 1998 – 2002 Member, Emedicine 1999 Ad hoc Reviewer, Clinical Nutrition 2000 – 2002 Editor-in-Chief, Journal of Parenteral and Enteral Nutrition 2000 – 2007 Member, Journal of the American College of Surgeons 2000 – 2009 Member, Medscape General Medicine, WebMD 2001 Ad hoc Reviewer, American Journal of Kidney Diseases 2002 Ad hoc Reviewer, Critical Care Medicine 2002 – 2015 Member, New England Journal of Medicine 2015 – Present Ad hoc Reviewer, New England Journal of Medicine 2003 – 2014 Member, Surgery

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2004 – 2005 Ad hoc Reviewer, World Journal of Surgery 2004 Ad hoc Reviewer, Digestive Diseases and Sciences 2004 – 2008 Member, American College of Surgeons Web Portal 2005 – 2009 Member, Unbound Surgery 2008 Ad hoc Reviewer, Journal of the American Medical Association Surgery 2010 Ad hoc Reviewer, Journal of Clinical Gastroenterology 2010 – 2014 Advisor to the Editorial Board, Journal of Surgical Radiology 2010 – 2012 Member, International Scholarly Research Network (ISRN) Surgery 2011 Ad hoc Reviewer, Annals of Surgery 2012 Ad hoc Reviewer, Clinical Gastroenterology and Hepatology 2012 Ad hoc Reviewer, Obesity 2015 Ad hoc Reviewer, American Journal of Physiology – Cell Physiology 2015 Ad hoc Reviewer, American Journal of Physiology – Heart and

Circulatory Physiology 2015 Ad hoc Reviewer, American Journal of Physiology – Endocrinology and Metabolism 2016 Ad hoc Reviewer, The Lancet 2016 Ad hoc Reviewer, British Journal of Pharmacology 2016 Ad hoc Reviewer, The Lancet Diabetes and Endocrinology 2019 Member, Editorial Board of NEJM Catalyst Innovations in Care Delivery Selected Awards or Honors 1971 Scholarship, Harvard University, Boston, MA 1975 Scholarship, Washington University-St. Louis, St. Louis, MO 1983 Resident's Research Award, Association for Academic Surgery 1985 Jonathan Rhoads Surgical Resident's Research Award, University of Pennsylvania 1986 Election, Alpha Omega Alpha 1986 – 1988 National Research Service Award 1989 – 1993 Robert Wood Johnson Harold Amos Faculty Development Award 1990 Greater Boston YMCA Black Achievement Award 1990 Stanley Dudrick Research Scholar Award (American Society for Parenteral and Enteral Nutrition) 1992 Peer Recognition Award, Harvard Community Health Plan 1993 Matson Award for Teaching, Brigham and Women's Hospital 1993 William E. Matory Award, Surgical Section, National Medical Association 1993 Diamond Award Winner, Harvard Community Health Plan 1995 Cited in "Noteworthy Publications by African-American Surgeons in

Commemoration of the 100th anniversary of the National Medical Association, 1895-1995" edited by Vernon J. Henderson, M.D., and Claude Organ, M.D.

1996 Outstanding Service Award, Harvard Community Health Plan 1996 Nominated for the Prize for Excellence in Teaching, Harvard Medical School 2004 Alumni Achievement Award, Washington University – St. Louis School of Medicine 2004 Who’s Who in Medical Sciences Education (WWMSE) 2006 Recognized by National Library of Medicine in “Opening Doors: Contemporary

African American Academic Surgeons” (2007) 2008 Life Member, Fellows Leadership Society, American College of Surgeons 2008 Inclusion in “Guide to America’s Top Surgeons” of the Consumer’s Research Council of America 2010 Julius A. Mackie Distinguished Graduate Award, University of Pennsylvania

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2013 National Medical Association (NMA) Presidential Award 2019 Elected Member, Sigma Pi Phi Fraternity EDUCATIONAL ACTIVITIES Peer Reviewed Publications

1. Jacobs DO, Albina JE, Settle RG, Wolf G, Rombeau JL. In vitro identification of carbon tetrachloride induced fatty liver infiltration by proton nuclear magnetic resonance. Surg Forum 1983; 34:54-56.

2. Jacobs DO, Melnik G, Forlaw L, Settle RG, Rombeau JL. Impact of a nutritional support service on

VA surgical patients. J Am Coll Nutr 1984; 3:311-315.

3. Koruda MJ, Argov Z, Maris J, Rolandelli R, Settle RG, Jacobs DO, Chance B, Rombeau JL. 31-Phosphorus nuclear magnetic resonance spectroscopy of stimulated muscle during starvation. Surg Forum 1985; 36:61-63.

4. Albina JE, Jacobs DO, Melnik G, Settle RG, Stein TP, Rombeau JL. Nitrogen utilization from

elemental diets. JPEN J Parenter Enter Nutr 1985; 2:189-195.

5. Jacobs DO, Clarke J, Settle RG, Sachdeva AK, Wheeler JE, Trerotola SO, Wolf GL, Rombeau JL. The identification of experimentally induced appendicitis using in vitro NMR. J Surg Res 1985; 39:16-24.

6. Jacobs DO, Trerotola S, Settle RG, Rolandelli RH, Wolf GL, Rombeau JL. The in vitro detection of

fatty liver infiltration in protein depleted rats using NMR. J Surg Res 1985; 39:25-30.

7. Rolandelli RH, Saul SH, Settle RG, Jacobs DO, Singer R, Wolf GL, Rombeau JL. Identification of experimentally induced colitis by in vitro NMR. Physiol Chem Phys Med NMR 1985; 17:197-203.

8. Scheindlin B, Jacobs DO, Settle RG, Wolf GL, Rombeau JL. The comparative influence of

anesthetics on the in vitro proton relaxation times in rat liver. Physiol Chem Phys Med NMR 1985; 17:71-75.

9. Miller JE, Whitman GJ, Iozzo RV, Jacobs DO, Ziegler MM. Early diagnosis of experimental

necrotizing enterocolitis using proton nuclear magnetic resonance. J Surg Res 1985; 39:322-330.

10. Koruda MJ, Zimmler A, Settle RG, Jacobs DO, Rolandelli RH, Wolf GL, Rombeau JL. Assessing burn wound depth using in vitro nuclear magnetic resonance. J Surg Res 1986; 40:475-481.

11. Jacobs DO, Settle RG, Trerotola S, Wolf GL, Rombeau JL. The detection of TPN induced fatty liver

infiltration in the rat by in vitro proton nuclear magnetic resonance. JPEN J Parenter Enter Nutr 1986; 10:177-183.

12. Jacobs DO, Evans DA, O'Dwyer ST, Smith RJ, Wilmore DW. Disparate effects of 5-FU on the ileum

and colon of enterally fed rats with protection by dietary glutamine. Surg Forum 1987; 38:45-47.

13. Rolandelli R, Saul SH, Settle RG, Jacobs DO, Trerotola S, Rombeau JL. A comparison of parenteral nutrition and enteral feeding with pectin in experimental colitis in the rat. Am J Clin Nutr 1988; 47:715-21.

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14. Wang XD, Jacobs DO, O'Dwyer ST, Smith RJ, Wilmore DW. Glutamine-enriched parenteral

nutrition prevents mucosal atrophy following massive small bowel resection. Surg Forum 1988; 39:44-46.

15. Jacobs DO, Evans DA, Smith RJ, Wilmore DW. Combined effects of glutamine and epidermal

growth factor on the rat intestine. Surgery 1988; 104:358-364.

16. Wilmore DW, Smith RJ, O'Dwyer ST, Jacobs DO, Zeigler TR, Wang XD. The gut--a central organ after surgical stress. Surgery 1988; 104:917-923.

17. Jacobs DO, Maris J, Fried R, Settle RG, Rolandelli RH, Koruda MJ, Chance B, Rombeau JL. In vivo 31P

nuclear magnetic resonance (NMR) spectroscopy of rat hind limb skeletal muscle during sepsis. Arch Surg 1988; 123:1425-1428.

18. Hulton NR, Johnson DJ, Evans A, Jacobs DO, Wilmore DW. Inhibition of prostaglandin synthesis

improves post-operative nitrogen balance. Clin Nutr 1988; 7:81-84.

19. Lowe DK, Benfell K, Smith RJ, Jacobs DO, Murawski B, Ziegler TR, Wilmore DW. Glutamine-enriched parenteral nutrition is safe in normal humans. Surg Forum 1989; 40:9-11.

20. van Lanschot JJB, Mealy K, Evans DA, Jacobs DO, Wilmore DW. Splenectomy abolishes the diuresis

associated with tumor necrosis factor (TNF). Surg Forum 1989; 40:62-65.

21. Evans DA, Jacobs DO, Revhaug A, Wilmore DW. The effects of TNF and their selective inhibition by ibuprofen. Ann Surg 1989; 209:312-321.

22. Evans DA, Jacobs DO, Smith RJ, Wilmore DW. Tumor necrosis factor enhances glucose uptake by

peripheral tissues. Am J Physiol 1989; 257:R1182-R1189.

23. Ziegler TR, Smith RJ, Jacobs DO, Helton WS, O'Dwyer, Wang XD, Wilmore DW. Glutamine metabolism and intestinal failure. Korean Journal of Nutrition 1989; 22:1017-1020.

24. Jacobs DO, Clarke JR, Settle RG, Trerotola SO, Sachdeva AK, Wolf GL, and Rombeau JL. Identification of human appendicitis by in vitro nuclear magnetic resonance. J Surg Res 1990; 48:107-110.

25. Scheltinga MR, Kimbrough TD, Jacobs DO, Wilmore DW. Altered cell membrane function in critical illness can be characterized by measuring body reactance. Surg Forum 1990; 41:43-44.

26. Helton WS, Jacobs DO, Bonner-Weir S, Bueno R, Smith RJ, Wilmore DW. Effects of glutamine-

enriched parenteral nutrition on the exocrine pancreas. (Winner 1989 Harry S. Vars Award for nutritional research from the American Society for Parenteral and Enteral Nutrition). JPEN J Parenter Enter Nutr 1990; 14:344-352.

27. Lowe DK, Benfell K, Smith RJ, Jacobs DO, Murawski B, Ziegler TR, Wilmore DW. The safety of

glutamine-enriched parenteral nutrient solutions in humans. Am J Clin Nutr 1990; 52:1101-6.

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28. Holtzman D, McFarland E, Jacobs DO, Offutt M, Neuringer L. Maturational increase in mouse brain creatine kinase reaction rates shown by phosphorus nuclear magnetic resonance. Dev Brain Research 1991; 58:181-188.

29. Scheltinga MR, Jacobs DO, Kimbrough TD, Wilmore DW. Alterations in body fluid content can be

detected by bioelectrical impedance analysis (BIA). J Surg Res 1991; 50:46-468.

30. Scheltinga MR, Helton WS, Rounds JD, Jacobs DO, Wilmore DW. Impedance electrodes positioned on proximal portions of limbs quantify fluid compartments in dogs. J Appl Physiol 1991; 70:2039-2044.

31. Jacobs DO, Kobayashi T, Imagire J, Kesselly BC, Grant C, Wilmore DW. Sepsis alters skeletal muscle

energetics and membrane function. Surgery 1991; 110:318-326.

32. Van Lanschot JJB, Mealy K, Jacobs DO, Evans DA, Wilmore DW. Splenectomy attenuates the inappropriate diuresis associated with tumor necrosis factor administration. Surg Gynecol Obstet 1991; 172:293-297.

33. Robinson MK, Hong RW, Rounds JD, Jacobs DO, Wilmore DW. Glutathione depletion enhances

bacterial translocation and alters immunologic status. Surg Forum 1991; 42: 65-67.

34. Gatzen C, Scheltinga MR, Kimbrough TD, Jacobs DO, Wilmore DW. Growth hormone attenuates the abnormal distribution of body water in critically ill surgical patients. Surgery 1992; 112:181-187.

35. Robinson MK, Rounds JD, Hong RW, Jacobs DO, Wilmore DW. Glutathione deficiency increases

organ dysfunction after hemorrhagic shock. Surgery 1992; 112:140-149.

36. Ziegler TR, Young LS, Benfell K, Scheltinga M, Hortos K, Bye R, Morrow FD, Jacobs DO, Smith RJ, Antin JH, Wilmore DW. Clinical and metabolic efficiency of glutamine-supplemented parenteral nutrition following bone marrow transplantation: A double blind, randomized trial. Ann Int Med 1992; 11:821-828.

37. Robinson MK, Ahn MS, Rounds JD, Cook JA, Jacobs DO, Wilmore DW. Parenteral glutathione

monoester enhances tissue antioxidant stores. JPEN J Parenter Enter Nutr 1992; 16:413-418.

38. Scheltinga MR, Jacobs DO, Kimbrough TD, Wilmore DW. Identifying body fluid distribution by measuring electrical impedance. J Trauma 1992; 33:665-670.

39. Morrissey T, Gatzen C, Rounds JD, Rose J, Kobayashi T, Robinson V, Wilmore DW, Jacobs DO.

During sepsis, alterations in fluid distribution are related to abnormal cellular energetics. Surg Forum 1992; 43:1-3.

40. Robinson MK, Kobayashi T, Rounds JD, Robinson V, DeRosa E, Wilmore DW, Jacobs DO. Glutamine

enhances hepatocellular energetics during sepsis. Surg Forum 1992; 43:171-174.

41. Kobayashi T, Robinson MK, Rounds JD, Robinson V, DeRosa E, Wilmore DW, Jacobs DO. Sepsis alters hepatocellular energetics as assessed by in vivo magnetic resonance spectroscopy. Surg Forum 1992; 43:11-13.

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42. Holtzman D, Offutt M, Tsuji M, Neuringer L, Jacobs DO. Creatine kinase reaction rate in the cyanide poisoned mouse brain. J Cereb Blood Flow Metab 1993; 13:153-161.

43. Robinson MK, Rodrick ML, Jacobs DO, Rounds JD, Collins KH, Saporoschetz IB, Mannick JA,

Wilmore DW. Glutathione depletion in vivo impairs T-cell and macrophage immune function. Arch Surg 1993; 128(1):29-34.

44. Kobayashi T, Robinson MK, Robinson VD, DeRosa Eve, Wilmore DW, Jacobs DO. Glutathione

depletion induces hepatocellular injury and alters high energy phosphate metabolism. J Surg Res 1993; 54:189-195.

45. Evans DA, Jacobs DO, Rounds JD, Wilmore DW. The effects of tumor necrosis factor after removal

of the gut. J Surg Res 1993; 54:39-45.

46. Mann DV, DeRosa E, Rounds JD, Rose J, Robinson MK, Wilmore DW, Jacobs DO. Assessment of outcome following hemorrhagic shock by dynamic monitoring of intracellular energetics. Surg Forum 1993; 44:43-45.

47. Santos AA, Shapiro L, Lynch EA, Brown EF, Jacobs DO, Dinarello CA, Wolff SM, Wilmore DW.

Tumor necrosis factor soluble receptor p55: Endogenous counter-regulatory glycoprotein. Surg Forum 1993; 44:119-121.

48. Evans, DA, Jacobs DO, Wilmore DW. The effects of tumor necrosis factor on protein metabolism. Br J Surg 1993; 80:1019-1023.

49. Young LS, Bye R, Scheltinga M, Ziegler T, Jacobs DO, Wilmore DW. Patients receiving glutamine

supplemented intravenous feedings report an improvement in mood. JPEN J Parenter Enter Nutr 1993; 17(5):422-427.

50. Santos AA, Browning JL, Scheltinga MR, Lynch EA, Brown EF, Lawton P, Chambers E, Douglas I,

Benjamin CD, Dinarello CA, Wolff SM, Jacobs DO, Wilmore DW. Are events after endotoxemia related to circulating phospholipase A2? Ann Surg 1994; 219(2):183-192.

51. Santos AA, Rodrick ML, Jacobs DO, Dinarello C, Wolff SM, Mannick J, Wilmore DW. Does the route

of feeding modify the inflammatory response? Ann Surg 1994; 220(2):155-163.

52. Mizobata Y, Rounds JD, DeRosa E, Rose J, Wilmore DW, Jacobs DO. 31P magnetic resonance spectroscopy demonstrates expansion of the extracellular space in skeletal muscle of starved rats. J Surg Res 1994; 56:491-499.

53. Resnick MB, Jacobs DO, Brodsky GL. Multifocal adenocarcinoma in situ with underlying carcinoid

tumor of the gallbladder. Arch Path Lab Med 1994; 118(9):933-934.

54. Mitsuo T, Rounds J, Rose J, Wilmore DW, Jacobs DO. Early changes in sodium distribution induced by sepsis. Surg Forum 1995; 46:30-32.

55. Denno R, Rounds JD, Mitsuo T, Cook C, Rodrick ML, Mannick JA, Wilmore DW, Jacobs DO.

Alterations in hepatic and skeletal muscle energetics during sepsis are associated with endotoxemia and serum complement activation. Surg Forum 1995; 46:158-161.

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56. Mizobata Y, Prechek D, Rounds DJ, Robinson V, Wilmore DW, Jacobs DO. The duration of infection modifies mitochondrial oxidative capacity in rat skeletal muscle. J Surg Res 1995; 59:165-173.

57. Jacobs DO. Use of bioelectrical impedance analysis measurements in the clinical management of

critical illness. Am J Clin Nutr 1996; 64(suppl):498s-502s.

58. Mitsuo T, Rounds J, Prechek D, Wilmore DW, Jacobs DO. Glucocorticoid receptor antagonism by mifepristone alters phosphocreatine breakdown during sepsis. Arch Surg 1996; 131:1179-1185.

59. Mann DV, Robinson MK, Rounds JD, DeRosa E, Niles DA, Ingwall JS, Wilmore DW, Jacobs DO.

Superiority of blood over saline resuscitation from hemorrhagic shock: A 31-phosphorus magnetic resonance study. Ann Surg 1997; 226:653-661.

60. Robinson MK, Rustum RR, Chambers EA, Rounds JD, Wilmore DW, Jacobs DO. Starvation enhances hepatic free radical release following endotoxemia. J Surg Res 1997; 69(2):325-30.

61. Chertow GM, McManus KD, Jacobs DO. Successful initiation of weight loss with fenfluramine and

phentermine in a patient on hemodialysis. J Renal Nutr 1997; 7:155-157.

62. Chertow GM, Jacobs DO, Lazarus JM, Lew NL, Lowrie EG. Phase angle predicts survival in hemodialysis patients. J Renal Nutr 1997; 7:204-207.

63. Lara TM, Jacobs DO. Effect of critical illness and nutritional support on mucosal mass and

function. Clin Nutr 1998; 17(3):99-105.

64. Lara TM, Wong MS, Rounds J, Prechek D, Robinson MK, Jacobs DO. Skeletal muscle phosphocreatine (PCr) depletion depresses myocellular energy status in sepsis. Arch Surg 1998; 133:1316-1321.

65. Miyagatani Y, Rounds JD, Chambers EA, Robinson MK, Jacobs DO. High dose vitamin C enhances

hepatic glutathione levels and increases survival of septic rats. Surg Forum 1998; 49:55-56.

66. Jasleen J, Severy P, Jacobs DO, Zinner M, Ashley S. Glucagon-like peptide-2 (GLP-2) stimulates intestinal epithelial cell cycle progression in vitro. Surg Forum 1998; 49:131-132.

67. Wong MS, Robinson MK, Lara TM, Pechet TTV, Wilmore DW, Jacobs DO. Hindlimb ischemia-

reperfusion impairs hepatocellular energetics and function via the complement system. Surg Forum 1998; 49:181-183.

68. Lee M, Jacobs DO, Chertow GM. Hemobilia mimicking acute cholecystitis following percutaneous

kidney biopsy. Nephrol Dial Transplant 1998; 13:2118-2120.

69. Trujillo EB, Robinson MK, Jacobs DO. Nutritional assessment in critically ill. Critical Care Nurse 1999; 19:67-78.

70. Trujillo EB, Young LS, Chertow GM, Randall S, Clemons T, Jacobs DO, Robinson MK. Metabolic and

monetary costs of avoidable parenteral nutrition use. JPEN J Parenter Enter Nutr 1999; 23:109-113.

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71. Wong MS, Lara TM, Kobzik L, Rounds J, Prechek D, Robinson MK, Jacobs DO. Hindlimb ischemia-reperfusion increases complement deposition and glycolysis. J Surg Res 1999; 85:130-135.

72. Tavakkolizadeh A, Shen R, Jasleen J, Soybel D, Jacobs DO, Zinner MJ, Ashley S, Whang E. Growth

hormone acutely stimulates intestinal sodium-glucose cotransporter activity. Gastroenterology 1999; 116:892.

73. Jasleen J, Shimoda N, Shen R, Tavakkolizadeh A, Whang EE, Jacobs DO, Zinner MJ, Ashley SW.

Signaling mechanisms of glucagon-like peptide-2 (GLP-2) induced intestinal epithelial cell proliferation. J Surg Res 2000; 90:13-18.

74. Tavakkolizadeh A, Shen R, Ibrahim P, Kormi N, Jacobs DO, Edelman E, Seifort P, Zinner MJ, Ashley

SW, Whang EE. Glucagon-like peptide-2 (GLP-2): A new treatment for chemotherapy-induced enteritis. J Surg Res 2000; 91:77-82.

75. Okamoto K, Wang W, Rounds J, Chambers E, Jacobs DO. Sublytic complement attacks increase

intracellular sodium in rat skeletal muscle. J Surg Res 2000; 90:174-182.

76. Tavakkolizadeh A, Shen R, Jasleen J, Soybel DI, Jacobs DO, Zinner MJ, Ashley SW, Whang EE. Effect of growth hormone on intestinal Na+/glucose cotransporter activity. J Parenteral Enteral Nutr 2000; 25:18-22.

77. Okamato K, Wang W, Rounds J, Chambers L, Jacobs DO. Complement activation favoring soluble

C5b-9 formation alters myocellular sodium homeostasis via multiple signaling processes. Surg Forum 2000; 51:219-220.

78. Tavakkolizadeh, Shen R, Abraham P, Kormi N, Seifert P, Edelman ER, Jacobs DO, Zinner MJ, Ashley

SW. Glucagon-like peptide 2 (glp-2) promotes intestinal recovery following chemotherapy-induced enteritis. Curr Surg 2000; 57: 502.

79. Shimoda N, Jasleen J, Rounds JD, Ashley SW, Jacobs DO. Sepsis increases the plasma membrane

content of 1 and 2 isoforms of Na+-K+ ATPase in rat skeletal muscle. Arch Surg 2001; 136:95-100.

80. Wang W, Okamoto K, Rounds J, Chambers E, Jacobs DO. In vitro complement activation favoring

soluble C5b-9 complex formation alters myocellular sodium homeostasis. Surgery 2001; 129:209-219.

81. Okamoto K, Wang W, Rounds J, Chambers EA, Jacobs DO. ATP from glycolysis is required for

normal sodium homeostasis in resting fast-twitch rodent skeletal muscle. Am J Physiol 2001; 281:E479-E488.

82. Jobst MA, Wang W, Zhao C, Shang L, Jacobs DO. Creatine transporter tyrosine phosphorylation

modulates myocellular creatine homeostasis during sepsis. Surg Forum 2001; 52:190-192.

83. Zhao CR, Shang LH, Wang W, Jacobs DO. Myocellular creatine and creatine transporter serine phosphorylation after starvation. J Surg Res 2002; 105:10-16.

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84. Wang W, Jobst MA, Bell B, Zhao CR, Shang LH, Jacobs DO. Creatine supplementation decreases tyrosine phosphorylation of the creatine transporter in skeletal muscle during sepsis. Am J Physiol Endocrinol Metab 2002; 282:E1046-E1054.

85. Wang W, Okamoto K, Jacobs DO. Complement activation alters myocellular sodium homeostasis

during polymicrobial sepsis. Crit Care Med 2002; 30:684-691.

86. Wang, Shang LH, Jacobs DO. Complement regulatory protein CD59 involves c-SRC related tyrosine phosphorylation of the creatine transporter in skeletal muscle during sepsis. Surgery 2002; 132(2):334-340.

87. Wang W, Okamoto K, Jacobs DO. Does endotoxin-activated complement alter myocellular sodium homeostasis during sepsis? J Trauma 2002; 52:951-961.

88. Robinson MK, Trujillo EB, Mogensen KM, Rounds J, McManus K, Jacobs DO. Improving Nutritional

Screening of Hospitalized Patients: The Role of Prealbumin. J Parent Ent Nutr 2003; 27:389-95.

89. Okamoto K, Wang W, Jacobs DO, Terai C. Activation of multiple signaling pathways by terminal complement complexes involved in myocellular sodium homeostasis. J Exp Med 2004; 202:113-22.

90. Kuo PC, Douglas AR, Oleski D, Jacobs DO, Schroeder RA. Determining benchmarks for evaluation

and management coding in an academic division of general surgery. J Am Coll Surg 2004; 199:124-30.

91. Jacobs DG, Jacobs DO, Kudsk KA, Moore FA, Oswanski MF, Poole GV, Sacks G, Scherer LR 3rd,

Sinclair KE. EAST Practice Management Guidelines Work Group. Practice management guidelines for nutritional support of the trauma patient. J Trauma 2004; 57:660-678.

92. Pietrobon R, Taylor M, Guller U, Higgins LD, Jacobs DO, Carey T. Predicting gender differences as

latent variables: summed scores, and individual item responses: a methods case study. Health Qual Life Outcomes 2004; 2:59.

93. Pietrobon R, Guller U, Martins H, Menezes AP, Jacobs DO, Higgins LD. A suite of web

applications to streamline the interdisciplinary collaboration in secondary data analyses. BMC Med Res Methodol 2004; 4:29.

94. Pietrobon R, Nielsen KC, Steele SM, Menezes AP, Martins H, Jacobs DO. Manuscript Architect: a

web application for scientific writing in virtual interdisciplinary groups. BMC Med Inform Decis Mak 2005; 5:15. Erratum in: BMC Med Inform Decis Mak 2007; 7:21.

95. Robinson MK, Mogensen KM, Grudinskas GF, Kohler S, Jacobs DO. Improved care and reduced costs for patients requiring peripherally inserted central catheters: the role of bedside ultrasound and a dedicated team. JPEN J Parenter Enteral Nutr 2005; 29:374-9.

96. Gable WH, Pappas TN, Jacobs DO, Cutler DA, Kuo PC. Productivity measures associated with a

patient access initiative. Ann Surg 2006; 243:604-611.

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97. Pietrobon R, Shah A, Kuo P, Harker M, McCready M, Butler C, Martins H, Moorman CT, Jacobs DO. Duke Surgery Research Central: an open-source web application for the improvement of compliance with research regulation. BMC Med Inform Decis Mak 2006; 6:32.

98. Shah A, Jacobs DO, Martins H, Harker M, Menezes A, McCready M, Pietrobon R. DADOS-Survey: an open-source application for CHERRIES-compliant Web surveys. BMC Med Inform Decis Mak 2006; 6:34.

99. Nguyen L, Shah A, Harker M, Martins H, McCready M, Menezes A, Jacobs DO, Pietrobon R.

DADOS- prospective: an open source application for Web-based prospective data collection. Source Code Biol Med 2006 Nov 13; 1:7.

100. Guevara C, Cook C, Herback N, Pietrobon R, Jacobs DO, Vail TP. Gender, racial, and ethnic

disclosure in NIH K-Award funded diabetes and obesity clinical trials. Account Res. 2006 Oct-Dec; 13(4):311-24.

101. Pietrobon R, Lima R, Shah A, Jacobs DO, Harker M, McCready M, Martins H, Richardson W. Duke Surgery Patient Safety: an open-source application for anonymous reporting of adverse and near-miss surgical events. Ann Surg Innov Res 2007 May 1; 1:5.

102. Cook C, Santos GC, Lima R, Pietrobon R, Jacobs DO, Richardson W. Geographic variation in lumbar fusion for degenerative disorders: 1990-2000. Spine J 2007 Sep-Oct; 7:552-7.

103. Shah A, Braga L, Braga-Baiak A, Jacobs DO, Pietrobon R. The association of departmental leadership gender with that of faculty and residents in radiology. Acad Radiol 2007 Aug; 14(8):998-1003.

104. Shah A, Pietrobon R, Cook C, Sheth NP, Nguyen L, Guo L, Jacobs DO, Kuo PC. Little science, big science: strategies for research portfolio selection in academic surgery departments. Ann Surg 2007 Dec; 246(6):1110-5.

105. Preston RJ, Marcozzi D, Lima R, Pietrobon R, Braga L, Jacobs DO. The effect of evacuation on the number of victims following hazardous chemical release. Prehosp Emerg Care 2008 Jan-Mar; 12:18-23.

106. Kuo PC, Schroeder RP, Shah A, Shah J, Jacobs DO, Pietrobon R. “Ghost” publications among applicants to a general surgery residency program. J Am Coll Surg 2008 Oct; 207:485-489.

107. Scarborough JE, Bennett KM, Schroeder RA, Swedish TB, Jacobs DO, Kuo PC. Will the clinicians support the researchers and teachers? Results of a salary satisfaction survey of 947 academic surgeons. Ann Surg 2009 Sep; 250(3):432-439.

108. Alexis M, Clary B, Jacobs DO, Pryor A. Duke surgical education and activities laboratory and the comprehensive educational institute. J Surg Edu 2010 Sep-Oct; 67(5):338-340.

109. Darrabie MD, Arciniegas AJ, Mishra R, Bowles DE, Jacobs DO*, Santacruz L*. AMPK and substrate availability regulate creatine transport in cultured cardiomyocytes. Am J Physiol Endocrinol Metab 2011 May; 300(5): E870-876. (*Jacobs and Santacruz contributed equally to this work).

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110. Hadeed JG, Walsh MD, Pappas TN, Pestana IA, Tyler DS, Levinson H, Mantyh C, Jacobs DO, Lagoo-Deenadalayan SA, Erdmann D. Complex Abdominal Wall Hernias: A New Classification System and Approach to Management Based on Review of 133 Consecutive Patients. Ann Plast Surg 2011 May; 66(5):497-503.

111. Sudan R, Salter M, Lynch T, Jacobs DO. Bariatric surgery utilizing a networking and teleconferencing to serve remote patients in the Veterans Administration Health Care System: feasibility and results. Am J Surg 2011 Jul; 202(1):71-76.

112. Sudan R, Salter M, Lynch T, Jacobs DO. Bariatric surgery using a network and teleconferencing to serve remote patients in the Veterans Administration Health Care System: Feasibility and results. Am J Surg. 2011;202(1):71-6.

113. Worni M, Akushevich I, Gloor B, Scarborough J, Chino JP, Jacobs DO, Hahn SM, Clary BM, Pietrobon R, Shah A. Adjuvant radiotherapy in the treatment of invasive intraductal papillary mucinous neoplasm of the pancreas: an analysis of the surveillance, epidemiology, and end results registry. Ann Surg Oncol 2012 April; 19(4):1316-23.

114. Worni M, Guller U, Shah A, Gandhi M, Shah J, Rajgor D, Pietrobon R, Jacobs DO, Ostbye T. Cholecystectomy concomitant with laparoscopic gastric bypass: a trend analysis of the nationwide inpatient sample from 2001 to 2008. Obes Surg 2012 Feb; 22(2):220-9.

115. Sudan R, Bennett KM, Jacobs DO, Sudan DL. Multifactorial analysis of the learning curve for robot-assisted laparoscopic biliopancreatic diversion with duodenal switch. Ann Surg 2012 May; 255(5):940-945.

116. Worni M, Ostbye T, Gandhi, M, Rajgor D, Jacobs DO, Shah J, Shah A, Pietrobon R, Gueller U. Laparoscopic appendectomy outcomes on the weekend and during the week are no different: a national study of 151,774 patients. World J Surg 2012 Jul; 36:1527-33.

117. Darrabie M, Arciniegas A, Mishra R, Pinilla M, Santacruz L, Jacobs DO. Exposing cardiomyocytes to subclinical concentrations of doxorubicin rapidly reduces their creatine transport. Am J Physiol Heart Circl Physiol 2012 Sept; 303(5):H539-48.

118. Worni M, Castleberry AW, Clary BM, Gloor B, Carvalho E, Jacobs DO, Pietrobon R, Scarborough JE, White RR. Concomitant vascular reconstruction during pancreatectomy for malignant disease: A propensity score-adjusted, population-based trend analysis involving 10,206 patients. Arch Surg 2012 Dec; 17:1-8.

119. Worni M, Østbye T, Gandhi M, Rajgor D, Shah J, Shah A, Jacobs DO, et al. Laparoscopic appendectomy outcomes on the weekend and during the week are no different: A national study of 151,774 patients. World J Surg. 2012; 36(7):1527-33.

120. Worni M, Guller U, Maciejewski ML, Curtis LH, Gandhi M, Pietrobon R, Jacobs DO, Ostbye T. Racial Differences Among Patients Undergoing Laparoscopic Gastric Bypass Surgery: a Population-Based Trend Analysis from 2002 to 2008. Obes Surg 2013 Feb; 23(2):226-33.

121. Sartini S, Sestili P, Colombo E, Martinelli C, Bartolini F, Ciuffoli S, Jacobs DO, et al. Creatine affects in vitro electrophysiological maturation of neuroblasts and protects them from oxidative stress. J Neurosci Res. 2012; 90(2):435-46.

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122. Worni M, Castleberry AW, Clary BM, Gloor B, Carvalho E, Jacobs DO, et al. Concomitant vascular reconstruction during pancreatectomy for malignant disease: A propensity score-adjusted, population-based trend analysis involving 10 206 patients. JAMA Surg. 2013; 148(4):331-8.

123. Santacruz L, Hernandez A, Nienaber J, Mishra R, Pinilla M, Burchette J, Mao L, Rockman H, Jacobs DO. Normal cardiac function in mice with supra-physiological cardiac creatine levels. Am J Physiol Heart Circ Physiol 2014 306(3):H373-381.

124. Santacruz L, Jacobs DO. Structural correlates of the creatine transporter function regulation: the undiscovered country. Amino Acids 2016 48(8):2049-2055.

125. Santacruz L, Darrabie M, Mantilla J, Mishra R, Feger B, Jacobs DO. Creatine Supplementation Reduces Doxorubicin-Induced Cardiomyocellular Injury. Cardiovasc Toxicol, 2015 Apr;15(2): 180-8.

126. Santacruz L, Darrabie M, Mantilla J, Mishra R, Jacobs DO. Removal of potential phosphorylation sites does not alter creatine transporter response to PKC or substrate availability. Cell Physiol Biochem. 2015;37(1):353-60.

Invited or Contributed Reports Resulting from Meetings, Conferences and Symposia

1. Jacobs DO, Mann DV. Changes in skeletal muscle energetics during sepsis. In: Vincent JL, ed. Yearbook of Intensive Care and Emergency Medicine, 1993. Heidelberg: Springer-Verlag 1993; 21-35.

2. Jacobs DO, Robinson MK. Applications of magnetic resonance spectroscopy to nutrition and metabolism. In: Vincent JL, ed. Update in Intensive Care and Emergency Medicine, vol. 17, Metabolic support of the critically ill patient. Heidelberg: Springer-Verlag 1993; 18-45.

3. Klein S, Kinney J, Jeejeebhoy K, Alpers D, Hellerstein M, Murray M, Twomey, Jacobs DO, and others. Nutrition support in clinical practice: review of published data and recommendations for future research directions. J Paren Enter Nutr (JPEN) 1997; 21: 133-156.

Chapters, Reviews, Editorials, Books and other Educationally Relevant Publications

1. Jacobs DO, Borass MC, Rombeau JL. Enteral Nutrition and Liver Disease. In: Rombeau JL and Caldwell M, eds. Clinical Nutrition Volume I: Enteral and Tube Feeding. WB Saunders; 1984:376-402.

2. MacBurney MM, Jacobs DO, Apelgren KN, Melnik G, Rombeau JL. Modular Feeding. In: Rombeau

JL and Caldwell M, eds. Clinical Nutrition Volume I: Enteral and Tube Feeding. WB Saunders; 1984:199-211.

3. Rombeau JL, Jacobs DO. Nasoenteric Tube Feeding. In: Rombeau JL and Caldwell M, eds. Clinical

Nutrition Volume I: Enteral and Tube Feeding. WB Saunders; 1984:261-274.

4. Rombeau JL and Jacobs DO. Enteral Nutrition and the Surgical Patient. In: Greene HL, ed. Enteral Nutrition: Mead Johnson Symposium Series no. 2. Mead Johnson Nutritional Division; 1984:110-1263.

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5. Bernard M, Jacobs DO, Rombeau JL (eds). Nutritional Care of the Hospitalized Patient. 1st ed. Philadelphia: WB Saunders; 1985.

6. Jacobs DO, Rolandelli RH, Fried R, Rombeau JL. Malnutrition and Inflammatory Bowel Disease: Indications for and Complications of Parenteral Nutritional Support. In: Rombeau JL and Caldwell M, eds. Clinical Nutrition Volume II: Parenteral Nutrition. WB Saunders; 1985:380-400.

7. Jacobs DO, Albina JE, Bernard M. Energy requirements. In: Rombeau JL, Caldwell MD, Forlaw L,

Guenter PA, eds. Atlas of Nutritional Support Techniques. Little, Brown, and Co.; 1989:54-57.

8. Jacobs DO, and Wilmore DW. Hormone-Substrate Interactions. In: Rombeau JL and Caldwell M, eds. Clinical Nutrition Volume I: Enteral and Tube Feeding. 2nd ed. WB Saunders; 1990:34-53.

9. Guenther P, Jacobs DO, Rombeau JL. Administration and Delivery of Enteral Nutrition, In: Rombeau

JL, and Caldwell M, Clinical Nutrition Volume I: Enteral and Tube Feeding. 2nd ed. WB Saunders; 1990:192-203.

10. Wilmore DW, O'Dwyer ST, Jacobs DO, Wang XD, and Smith RJ. Glutamine Supplemented Nutrition

Supports the Intestinal Mucosa. In: Tanaka T, and Okada A, eds. Nutritional Support in Organ Failure. Elsevier Science Publishers (Biomedical Division); 1990:217-225.

11. Lowe D, Jacobs DO, and Wilmore DW. Metabolic Background. In: Fischer JE, ed. Total Parenteral

Nutrition. 2nd ed., Little, Brown and Co.; 1991:165-180.

12. Jacobs DO, Scheltinga M. Metabolic Assessment In: Rombeau JL, and Caldwell M, eds. Clinical Nutrition Volume II: Parenteral Nutrition. 2nd ed. WB Saunders; 1993:245-2743.

13. Jacobs DO. Parenteral Nutrition in Adults. In: Rakel RE, ed. Conn's Current Therapy. WB Saunders;

1993:575-586.

14. Jacobs DO. Nutritional Care of Perioperative Patients. In: Nutrition. Vol. 3. Bristol-Myers Squibb (Mead Johnson); 1993:32-40.

15. Jacobs DO. Bioelectrical Impedance Analysis: A Way to Assess Changes in Body Cell Mass in

Patients with Acquired Immunodeficiency Syndrome (AIDS). JPEN J Parenter Enter Nutr 1993; 17(5): 401-402.

16. Jacobs DO, Becker JM. Surgical Management of Ulcerative Colitis. In: Targan SR, Shanahan F, eds. Inflammatory Bowel Disease: from Bench to Bedside. Williams and Wilkins; 1994:567-581.

17. Jacobs DO, Becker JM. Colonic Surgery, Including Ileostomy and Colostomy. In Quigley EMM, and Sorrell MF, eds. Medical Care of the Gastrointestinal Surgical Patient. Williams and Wilkins; 1994:353-390.

18. Ziegler TR, Jacobs DO. Anabolic Hormones. In: Torosian MH, ed. Nutrition for the Hospitalized

Patient: Basic Science and Principles of Practice. Marcel-Dekker, Inc.; 1995:207-222.

19. Jacobs DO, Becker JM. Peptic Ulcer Surgical Treatment, in Whom and When. In: Snape W, Jr., ed. Consultations in Gastroenterology. WB Saunders; 1995:345-356.

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20. Desai S, Jacobs DO. Growth Hormone in the Post-Operative Patient. In: Torosian MH, ed. Growth Hormone in Critical Illness. Marcel-Dekker, Inc.; 1995:118-139.

21. Jacobs DO, Robinson MK. Body Composition. In: Fischer JE, ed. Nutrition and Metabolism in the

Surgical Patient, 2nd ed. Little, Brown, and Co.; 1996:3-27.

22. Jacobs DO. Another Potential Clinical Role for Glutamine-Supplemented Parenteral Nutritional? Nutrition 1996; 12(5): 375.

23. Jacobs DO. Use of Bioelectrical Impedance Analysis Measurements in the Clinical Management of

Critical Illness. Am Journal Clin Nutrition 1996; 64(suppl): 498s-502s.

24. Jacobs DO. Bioelectrical Impedance Analysis: Implications for Clinical Practice. Nutrition in Clinical Practice 1997; 12 (5): 201-210.

25. Wong MS, Jacobs DO. Pancreatic Pseudocyst: The Controversial Value of Total Parenteral

Nutrition. Current Literature Review, Nutrition in Clinical Practice 1997; 12:280.

26. Jacobs DO. The Esophagus. In: Niederhuber JE, ed. Fundamentals of Surgery. Appleton and Lange, Inc.; 1998:267-287.

27. Trujillo E, Robinson MK, Jacobs DO. Nutrition and Critical Illness. In: Merritt RJ et al, eds. The

A.S.P.E.N. Nutrition Support Practice Manual. American Society for Parenteral and Enteral Nutrition; 1998:18-1 through 18-14.

28. Wong MS, Jacobs DO. Endoscopic Nasoenteral Feeding Tube Placement Following Cardiothoracic

Surgery. Nutrition in Clinical Practice 1998; 13(2): 95-963.

29. Lara T, Jacobs DO. The Effects of Critical Illness and Nutritional Support of Intestinal Mucosal Mass and Function. Clinical Nutrition 1998; 17: 99-105.

30. Trujillo E, Jacobs DO. Parenteral Nutrition in Adults. In: Rakel RE, ed. Conn's Current Therapy. WB Saunders; 1999:598-612.

31. Trujillo EB, Robinson MK, Jacobs DO. Nutritional Assessment in the Critically Ill. Critical Care Nurse 1999; 19: 67–78.

32. Bridges KJ, Trujillo EB, Jacobs DO. Alcohol-related Thiamine Deficiency and Malnutrition. Critical Care Nurse 1999; 19: 80-85.

33. Souba WW, Alverdy JC, Jacobs DO, Kudsk KA, Rombeau JL. Symposium: Nutritional Support for Surgical Patients. Contemporary Surgery 1999; 55: 96-108.

34. Jacobs DO, Wong M. Metabolic Assessment. World Journal of Surgery 2000; 24(12): 1460-1467.

35. Jacobs DO, Trujillo E, Chertow GM. Metabolic Assessment In: Rombeau JL, and Caldwell M, eds. Clinical Nutrition Volume II: Parenteral Nutrition. 3rd ed. WB Saunders; 2000:80-108.

36. Kudsk KA, Jacobs DO. Section 1: Care of Surgical Patient, Nutrition. In: Lowry SJ, ed. Surgery: Basic

Science and Clinical Evidence. Springer-Verlag, Inc.; 2001:123-146.

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37. Trujillo EB, Robinson MK, Jacobs DO. Feeding Critically Ill Patients: Current Concepts. Critical Care

Nurse 2001; Vol. 21, 4: 60-69.

38. Jacobs DO, Matsuda T. Energetics. In: WW Souba and DW Wilmore, eds. Surgical Research. Academic Press, Inc. 2001:813-823.

39. Lara T, Jacobs DO. Nutrition, Metabolism and Wound Healing in the Elderly. In: Rosenthal RA,

Zenilman ME, eds. Principles and Practice of Geriatric Surgery 1st ed.: Springer-Verlag, Inc.; 2001:65-85.

40. Jacobs DO. Mesh Repair of Inguinal Hernias - Redux. N Engl J Med 2004; 350:1895-7.

41. Pappas TN, Jacobs DO. Laparoscopic Resection for Colon Cancer – The End of The Beginning? N

Engl J Med. 2004; 350: 2091-2.

42. Jacobs DO. Invited critique of Ramaswamy A, Lin E, Ramshaw BJ, and Smith CD. Early Effects of Helicobacter Pylori Infection in Patients Undergoing Bariatric Surgery. Arch Surg 2004; 139: 1093.

43. Jacobs DO. Department of Surgery, Duke University Medical Center, Durham, NC. Arch Surgery

2004; 139: 706-8.

44. Robinson MK, Gonzalez E, Jacobs DO. Bariatric Surgery and Reduction of Cardiovascular Risk Factors. In: Robinson M, Thomas A, eds. Obesity and Cardiovascular Disease. Taylor & Francis Group; 2006:347-364.

45. Jacobs DO, Heniford, BT, Splenic abscess. In: Emedicine. General Surgery. Online publication out of press.

46. White RR, Jacobs DO. Volvulus of Stomach and Small Bowel. In: Yeo CJ, Dempsey DT, Klein AS,

Pemberton JH, Peters JH, eds. Shackleford’s Surgery of the Alimentary Tract. Saunders; 2007:1035-1040.

47. Jacobs DO. (Editor) First Exposure to General Surgery. New York: McGraw-Hill 2007.

48. Jacobs DO, Robinson MK. Section 4, Chapter 16 Morbid Obesity and Operations. In: Zinner MS,

Ashley SW, eds. Maingot’s Abdominal Operations, 11th ed. McGraw-Hill Co., Inc.; 2007:455-479.

49. Jacobs DO. Clinical Practice. Diverticulitis. N Engl J Med 2007; 357: 2057-66.

50. Jacobs DO. (Book Review) Current Therapy of Trauma and Surgical Critical Care, and Trauma: Contemporary principles and therapy. N Engl J Med 2008; 359: 1078-1079.

51. Jacobs DO. Foreword In: Heart’s Vortex: Intracardiac Blood Flow Phenomena. Pasipoularides, A;

People’s Medical Publishing House – USA 2009:927.

52. Jacobs DO. (Book Review) War Surgery in Afghanistan and Iraq: A Series of Cases, 2003 – 2007. N Engl J Med 2009; 360: 737-738.

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53. Desai SS, Jacobs DO. (Editors). Clinical Review of Surgery. 3rd ed. New York, NY: Catalyst Publishers; 2009; 669.

54. Desai SS, Jacobs DO. (Editors). Clinical Review of Surgery, Q&A. 3rd ed. New York, NY: Catalyst Publishers; NY: Catalyst Publishers; 2009; 100.

55. Jacobs DO. Variation in Hospital Mortality Associated with Inpatient Surgery – An SOS. N Engl J

Med 2009; 361: 1398-1400.

56. Perez A, Mantyh C, Jacobs DO. Diverticula of the Alimentary Tract. In: Roberts RE, Bope ET, Kellerman RD, eds. Conn’s Current Therapy 2010. Elsevier; 2010:516-624. (Minor Revisions in 2011).

57. Jacobs DO. Discussions. Ann Surg. 2010; 252(3):541-3.

58. Hutcheson KA, Jacobs DO. Bleeding hemorrhoids. Gastrointestinal Bleeding: Springer; 2010. p. 133-44.

59. Jacobs DO. Improving surgical services in developing nations: Getting to go. World J Surg. 2010;34(11):2509-10.

60. Jacobs DO. Modern anatomy. J Surg Radiol. 2011; 2(3):216-9.

61. Lagoo-Deenadayalan SA, Jacobs DO. Nutrition in the Elderly. Principles and Practice of Geriatric Surgery. 2011:87.

62. Jacobs DO. Bariatric surgery - From treatment of disease to prevention? New Engl J Med. 2012; 367(8):764-5.

63. Jacobs DO. Improving surgical services in developing nations: getting to go. World J Surg 2010; 34(11):2509-10.

64. Lagoo-Deenadayala SA, Jacobs DO, Nutrition Chapter 6. In: Rosenthal RA, Zenilman ME, Katlic MR, eds. Principles and Practice of Geriatric Surgery. Springer Science and Business Media, LLC; 2011:87-106.

65. Jacobs DO. Modern Anatomy. Journal of Surgical Radiology 2011; 2(3): 216-219.

66. Sudan R, Jacobs DO. Biliopancreatic Diversion with Duodenal Switch. Surgical Clinics of North America; 2011; 1281-1293.

67. Perez A, Mantyh C, Jacobs DO. Diverticula of the Alimentary Tract. In: Roberts RE, Bope ET, Kellerman RD, eds. Conn’s Current Therapy 2012. Elsevier; 2012:562-564.

68. Desai SS, Jacobs DO. (Editors). Clinical Review for USMLE Step 1 3rd ed. New York, NY: Catalyst Publishers; NY: Catalyst Publishers; 2012.

69. Desai SS, Jacobs DO. (Editors). Clinical Review USMLE Step1. 1st electronic ed. (iPad). Catalyst Publishers; 2012.

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70. Jacobs DO. Bariatric Surgery - From Treatment of Disease to Prevention? N Engl J Med 2012 Aug 23; 367(8):764-765.

71. Darrabie M., Jacobs DO. Nutrition. Pocket ICU – Intensive Care Medicine, Aug 2012; Darrabie M, Jacobs DO. Nutrition. In: Frendl GM and Urman R, eds. Pocket ICU (Pocket Notebook Series). Lippincott, Williams & Wilkins; Chapter 9-1. Aug 2012. 1st ed.; Chapter 6 Nutrition, Feb 2017. 2nd ed.

72. Jacobs DO. Cut well, sew well, do well? N Engl J Med. 2013 Oct 10; 369(15): 1466-7.

73. Jacobs DO, Lara TM. Nutrition, Metabolism, and Wound Healing in the Elderly. Principles and practice of geriatric surgery. Springer Science & Business Media; 2013:65-85.

74. Santacruz L, Hernandez A, Nienaber J, Mishra R, Pinilla M, Burchette J, Jacobs DO, et al. Normal cardiac function in mice with supraphysiological cardiac creatine levels. Am J Physiol Heart Circ Physiol. 2014;306(3):H373-H381.

75. Jacobs DO. Clinical Practice. Hemorrhoids. N Engl J Med, 2014; 371:944-951.

76. Jacobs DO. Chapter 13e Abdominal Pain. In: J. L. Jameson, A. S. Fauci, D. L. Kasper et al. eds. Harrison’s Principles of Internal Medicine. 8th ed. McGraw-Hill Co., Inc; 2015:85.

77. Jacobs DO. Chapter 299 Acute Intestinal Obstruction In: J. L. Jameson, A. S. Fauci, D. L. Kasper et al. eds. Harrison’s Principles of Internal Medicine. 8th ed. McGraw-Hill Co., Inc; 2015:1627-1630.

78. Jacobs DO. Chapter 300 Acute Appendicitis and Peritonitis. In: J. L. Jameson, A. S. Fauci, D. L. Kasper et al. eds. Harrison’s Principles of Internal Medicine. 8th ed. McGraw-Hill Co., Inc; 2015:1631-1637.

79. Ekhaese O, Jacobs DO. Chapter 116 Bariatric Surgery. In: Podolsky DK, Camilleri M, Fitz JG, Kalloo AN, Shanahan F, Wang TC, eds. Yamada's Textbook of Gastroenterology. 6th ed. John Wiley & Sons Inc.; 2015:2242-64.

80. Jacobs DO. Hospital to Specific Skilled Nursing Facility Linkages – More may be better. Surgery. 2016;159(5):1469-70.

81. Ekhaese O, Jacobs DO, LaForte R. Chapter 63 Bariatric Surgery and Complications. In: Podolsky DK, Camilleri M, Fitz JG, Kalloo AN, Shanahan F, Wang TC, eds. Yamada's Atlas of Gastroenterology. 5th ed. John Wiley & Sons; 2016:495-500.

82. Jacobs DO. Chapter 323: Acute Intestinal Obstruction. In: J. L. Jameson, A. S. Fauci, D. L. Kasper et al. eds. Harrison’s Principles of Internal Medicine. 8th ed. McGraw-Hill Co., Inc.; 2018:2294-2297.

83. Jacobs DO. Chapter 12 Abdominal Pain. In: J. L. Jameson, A. S. Fauci, D. L. Kasper et al. eds. Harrison’s Principles of Internal Medicine. 8th ed. McGraw-Hill Co., Inc; 2018:81-84.

84. Jacobs DO. Chapter 324 Acute Appendicitis and Peritonitis. In: J. L. Jameson, A. S. Fauci, D. L. Kasper et al. eds. Harrison’s Principles of Internal Medicine. 8th ed. McGraw-Hill Co., Inc; 2018:2298-2302.

85. Jacobs DO. Hemorrhoids: what are the options in 2018? Curr Opin Gastroenterol, 2018 Jan; 34(1):46-49.

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86. Vickers SM, Britt LD, Deas DV, Ford HR, Hildreth JEK, Jacobs DO, Johnson RL, King Jr TE, Love TW, Mouton CP, Reece EA, Rice VM, Tyndall JA, Wilkes DS. Black medical leaders: Coronavirus magnifies racial inequities, with deadly consequences. USA Today. 2020, April 10. Available from: https://www.usatoday.com/story/opinion/2020/04/10/coronavirus-health-inequities-deadly-african-americans-column/5124088002/

87. Jacobs DO. Antibiotics for Appendicitis – Proceed with Caution. New Engl J Med. 2020 Nov 12; 383(20):1985-1986.

88. Jacobs DO, Moss RL, Lewin JS, Haley LL, Corwin SJ, Balser J, Nabel E, Harrison M, Newman K, Entwistle D, Mihaljevic T, Conroy J, Farrugia G, Van Gorder C, Borgstrom MP, Kaplan G, Kaiser LS, Klasko SK, Wheeler P, Nevin JE, Lubarsky D, Freese Decker T. Lessons from CEOs: Health Care Leaders Nationwide Respond to the Covid-19 Crisis. NEJM Catalyst Innovations in Care Delivery. 2020 Jul 29;1(4).

89. Jacobs DO, Hunter JG, Edwards R, Nabel EG, Lewin JS, Harrison M, Moss RL, Kaiser LS, Newman K, Farrugia G. Lessons from CEOs: How Are Health Systems Preparing for the Covid-19 Vaccine Rollout? NEJM Catalyst Innovations in Care Delivery. 2020 Dec 23;1(6).

Selected Abstracts

A1. Jacobs DO, Settle RG, Rombeau JL. A comparison of the effects of fish protein and lactalbumin on nitrogen balance in tube fed monkeys. JPEN J Parenter Enter Nutr 1982; 6: 589.

A2. Jacobs DO, Albina J, Settle RG, Wolf G, Rombeau JL. Nuclear magnetic resonance (NMR) and ethionine induced fatty liver infiltration. Mag Reson Med 1983; 2: 85.

A3. Jacobs DO, Rombeau JL, Albina JE, Settle RG. Effect of delivery method and site on nitrogen utilization in tube feeding. Am Fed Clin Res 1983; 31: 242A.

A4. Rombeau JL, Jacobs DO, Albina J, Settle RG, Wolf GL. Identification of metabolic changes in the

liver by in vitro NMR. Clin Nutr (Suppl) 1983; 2: 86.

A5. Jacobs DO, Settle RG, Ford E, et al: Aspiration in tube fed patients. Am J Clin Nutr 1984; 393: 675.

A6. Dempsey DT, Rombeau JL, Jacobs DO, Albina JA, Settle RG, Melnick G, Stein TP. Is all non-essential nitrogen equivalent? Fed Proc 1984; 43: 849.

A7. Scheindlin B, Jacobs DO, Patton V, Boyle P, Wolf GL, Rombeau JL. The influence of ether on in

vitro relaxation times in rat liver. Mag Reson Imag 1984; 2: 251.

A8. Jacobs DO, Whitman G, Maris J, Settle RG, Harken A, Rombeau JL. In vitro 31P NMR spectroscopy of rat skeletal muscle during starvation. JPEN J Parenter Enter Nutr 1985; 9: 107.

A9. Rolandelli RH, Saul S, Settle RG, Jacobs DO, Trerotola S, Rombeau JL. A comparison of parenteral

nutrition and feeding with pectin in experimental colitis. Clin Res 1985; 33: 708A.

A10. Jacobs DO, Whitman G, Settle R, Koruda MJ, Harken A, Chance B, Rombeau JL. High energy phosphates during starvation and refeeding using in vivo 31P NMR. JPEN J Parenter Enter Nutr 1987; 11: 14s.

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A11. Jacobs DO, Evans DA, O'Dwyer ST, Smith RJ, Wilmore DW. Trophic effects of glutamine-enriched

parenteral nutrition on colonic mucosa. JPEN J Parenter Enter Nutr 1988; 12(Supp 1): 6s.

A12. Helton WS, Jacobs DO, Smith RJ, Wilmore DW. Glutamine attenuates pancreatic atrophy. JPEN J Parenter Enter Nutr 1989; 13(Suppl 1): 11s.

A13. Holtzman D, McFarland E, Jacobs DO, Offutt M, Neuringer L. Developing mouse brain creatine

kinase in vivo. Pediatric Research 1989; 25(4 pt. 2): 356A.

A14. Scheltinga M, Helton W, Rounds J, Jacobs DO, Wilmore DW. Proximally placed electrodes detect and quantify minimal body water expansion. Am J Clin Nutr 1990; 51(3): 523.

A15. Jacobs DO, Kobayashi T, Wilmore DW. Starvation alters forward flux through the creatine kinase

(CK) pathway. Association for Academic Surgery 1990.

A16. Kobayashi T, Robinson MK, Robinson VD, Kesselly BC, Wilmore DW, Jacobs DO. Hepatic glutathione depletion causes hepatocellular injury and deranged high energy phosphate metabolism. Association for Academic Surgery 1991.

A17. Jacobs DO, Kobayashi T, Imagire J, Kesselly BC, Grant C, Wilmore DW. Sepsis alters skeletal

muscle energetics and membrane function. European Journal of Surgical Research 1991; supplement 1: 23.

A18. Kobayashi T, Kesselly B, Wilmore DW, Jacobs DO. Starvation reduces high energy phosphate

stores, work efficiency and oxidative capacity in skeletal muscle. JPEN J Parenter Enter Nutr 1991; 15 (Suppl 1): 10s.

A19. Ziegler TR, Young LS, Benfell K, Scheltinga M, Hortos K, Bye R, Morrow FD, Jacobs DO, Smith RJ,

Antin JH, Wilmore DW. Clinical and metabolic efficiency of glutamine-supplemented parenteral nutrition following bone marrow transplantation: A double blind, randomized trial. Blood 1991; 78: 193a.

A20. Robinson MK, Rodrick ML, Jacobs DO, Rounds JD, Mannick JA, Wilmore DW. Glutathione

depletion in vivo impairs T-cell and macrophage immune function. Surgical Infection Society 1992.

A21. Gatzen C, Scheltinga MR, Kimbrough TD, Jacobs DO, Wilmore DW. Exogenous growth hormone

attenuates abnormal water distribution in critically ill surgical patients. Brit J Surg 1992; 7: 449.

A22. Mizobata Y, Rounds JD, DeRosa E, Rose J, Wilmore DW, Jacobs DO. 31P magnetic resonance spectroscopy (31P-MRS) demonstrates expansion of the extracellular space in skeletal muscle of starved rats. Association for Academic Surgery 1993.

A23. Mann DV, Rounds JD, DeRosa E, Rose BA, Robinson MK, Wilmore DW, Jacobs DO. Dynamic

monitoring of intracellular glycolytic dysfunction following hemorrhagic shock and resuscitation. Association for Academic Surgery 1993.

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A24. Mann DV, Robinson MK, DeRosa E, Robinson V, Wilmore DW, Jacobs DO. Hemodilution to hematocrits of 20% and 30% impairs metabolic recovery from hemorrhagic shock. National Finalist, Winner Eastern Region, American College of Surgeons, Resident's Trauma Competition 1993.

A25. Kobayashi T, Robinson V, Wilmore DW, Jacobs DO. The effects of growth hormone on muscle

energetics during short term starvation. JPEN J Parenter Enter Nutr 1992; 16(Suppl 1): 23s.

A26. Mizobata Y, Brewster A, Rounds J, Mann DV, Wilmore DW, Jacobs DO. Parenteral refeeding after fasting restores anabolism but does not normalize water distribution in skeletal muscle. JPEN J Parenter Enter Nutr 1994; 18(Suppl 1): 18s.

A27. Brewster A, Precheck D, Niles D, Robinson V, Becker J, Jacobs DO. The effects of transforming growth Factor ß3 on intestinal healing after injury by 5-Fluorouracil. American Gastroenterological Association 1994. (2nd place winner in 1994 AGA student research competition).

A28. Santos AA, Jacobs DO, Dinarello CA, Wolff SM, Wilmore DW. Steroids: mechanism for inflammatory response suppression. Surgical Infection Society 1994.

A29. Mizobata Y, Prechek D, Wilmore DW, Jacobs DO. The duration of infection modifies

mitochondrial oxidative capacity in rat skeletal muscle. Association for Academic Surgery 1994.

A30. Niles D, Prechek D, Faris R, Jr Moore F, Hechtman H, Jacobs DO. The effects of short-term ischemia on skeletal muscle energetics and water distribution are unaffected by complement inhibition: A phosphorus magnetic resonance study. Upjohn Trauma Competition (finalist), Brigham and Women's Hospital 1995.

A31. Mitsuo T, Rounds J, Rose J, Wilmore DW, Jacobs DO. A novel method for measuring muscle

water distribution in sepsis using 31-Phosphorus magnetic resonance spectroscopy (31-P MRS). Crit Care Med 24 (supplement): A91 1996.

A32. Desai S, Mensah D, Rounds J, Wilmore D, Robinson M, Jacobs DO. Starvation induced expansion

of the extracellular space is ameliorated by growth hormone: an in vivo phosphorus magnetic resonance study. J Parent Enter Nutr 1996; 20(1): 19s. (Finalist for the Harry Var’s Young Investigator’s Award from the American Society for Parenteral and Enteral Nutrition).

A33. Desai S, Robinson M, Miller C, Rounds J, Jacobs DO. A new approach to the management of

refractory hypomagnesemia in short bowel patients. American Gastroenterological Association, Digestive Disease Week 1996.

A34. Mitsuo T, Rounds JD, Prechek D, Wilmore DW, Jacobs DO. Glucocorticoid receptor antagonism

by RU38486 alters phosphocreatine breakdown during sepsis, Surgical Infection Society 1996.

A35. Mitsuo T, Rounds JD, Prechek D, Wilmore DW, Jacobs DO. Glucocorticoid receptor antagonism by RU38486 alters sodium distribution within rat skeletal muscle during sepsis. Association for Academic Surgery 1996.

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A36. Robinson MK, Rustum RR, Ogaki N, Chambers EA, Rounds JD, Wilmore DW, Jacobs DO. Starvation enhances hepatic free radical release following endotoxemia. Association for Academic Surgery 1996.

A37. Trujillo E, Young L, Hameed M, Robinson MK, Jacobs DO. Nutrition support in the modern

medical ICU: Effect of weight loss and nutrition intake on patient outcome. American Society for Parenteral and Enteral Nutrition 1997.

A38. Ziegler TR, Desai SA, Gu L-H, Rounds JD, Prechek D, Robinson MK, Jacobs DO. Effects of growth

hormone (GH) administration on rat intestinal mass and gut IGF system mRNAs in the fed and fasted states. American Gastroenterological Association, DDW 1997.

A39. Myagatani Y, Rounds J, Prechek D, Robinson MK, Wilmore DW, Jacobs DO. The effects of high

dose vitamin C on abnormal myocellular energetics in septic rats. Association for Academic Surgery 1997.

A40. Trujillo E, Young LC, Wilmore DW, Jacobs DO, Robinson MK. Metabolic and monetary costs of

avoidable PN use. American Society for Parenteral and Enteral Nutrition 1998.

A41. Lara TM, Wong MS, Rounds J, Robinson MK, Wilmore DW, Jacobs DO. Depletion of skeletal muscle phosphocreatine (PCr) depresses myocellular energy state in sepsis. Surgical Infection Society 1998.

A42. Wong M, Robinson MK, Lara TM, Pechet TTV, Wilmore DW, Jacobs DO. Hindlimb ischemia-

reperfusion impairs hepatocellular integrity and function. 2nd Place Winner, Upjohn Trauma Competition, Brigham and Women's Hospital 1998.

A43. Wong M, Lara TM, Rounds J, Prechek D, Robinson MK, Jacobs DO. Hindlimb ischemia-reperfusion

(HIR) increases complement deposition and glycolysis. Association for Academic Surgery 1998.

A44. Lara TM, Rounds J, Robinson MK, Jacobs DO. Complement inhibition and myocellular energetics during sepsis. Society of Black Academic Surgeons 1999.

A45. Young LS, Barshop BA, Fanikos J, Robinson M, Trujillo E, Wilmore DW, Jacobs DO. Evaluation of a

new glutamine parenteral nutrition solution: Nutritional efficacy, cost and safety. American Society for Parenteral and Enteral Nutrition 1999.

A46. Tavakkolizadeh A, Shen R, Jasleen J, Soybel D, Jacobs DO, Zinner M, Ashley S, and Whang E.

Growth hormone acutely stimulates intestinal sodium-glucose co-transporter activity. American Gastroenterological Association, DDW 1999.

A47. Shimoda N, Jasleen J, Rounds J, Ashley S, Jacobs D. Sepsis does not change messenger RNA levels

for Na+-K+ ATPase but increases the plasma membrane content in rat skeletal muscle. Surgical Infection Society-Europe 1999.

A48. Hsu Y-P, Wang W, Chambers EA, Rounds JD, Jacobs DO, Robinson MK. Starvation increases hepatocyte susceptibility to oxidant injury. Association for Academic Surgery 1999.

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A49. Jasleen J, Shen R, Tavakkolizadeh A, Whang EE, Jacobs DO, Zinner MJ, Ashley SW. Signal transduction pathways in glucagon-like peptide-2 (GLP-2) induced intestinal epithelial cell proliferation. Association for Academic Surgery 1999.

A50. Tavakkolizadeh A, Shen R, Abraham P, Kormi N, Jacobs DO, Edelman E, Seifort P, Zinner MJ,

Ashley SW, Whang EE. Glucagon-like peptide-2 (GLP-2): A new treatment for chemotherapy-induced enteritis. Association for Academic Surgery 1999.

A51. Okamoto K, Wang W, Rounds J, Chambers E, Jacobs DO. Sublytic complement activation

increases intracellular sodium in isolated rat skeletal muscle. Association for Academic Surgery 1999.

A52. Wang W, Okamoto K, Rounds J, Jacobs DO. Starvation alters myocellular sodium homeostasis.

Digestive Disease Week 2000.

A53. Trujillo E, Jacobs DO, Robinson MK. Delayed identification and treatment of malnutrition in the hospitalized patient. American Society for Parenteral and Enteral Nutrition 2001.

A54. Okamoto K, Wang W, Jacobs DO. In vitro complement activation favoring soluable C5B-9

formation alters myocellular sodium homeostasis via protein kinase C and mitogen activated protein kinase. Association for Academic Surgery 2001.

A55. Zhao C, Wang W, Shang L, Jacobs DO. Changes in myocellular creatine (CN) content after

starvation are associated with reduced serine phosphorylation of the creatine transporter. Association for Academic Surgery 2001.

A56. Jobst MA, Wang W, Jacobs DO. Skeletal muscle creatine transport in sepsis. Association for

Academic Surgery 2001.

A57. Wang W, Shang L-H, Jacobs DO. Complement regulatory protein CD59 involves c-Src related tyrosine phosphorylation of the creatine transporter in skeletal muscle during sepsis. Society of University Surgeons 2002.

A58. Hohler S, Grudinskas G, Mogensen K, Jacobs DO. Improved care and reduced costs for patients requiring peripherally inserted central catheters: The role of beside ultrasound and a dedicated team. A.S.P.E.N. 2004.

A59. Darrabie MD, Santacurz-Toloza L, Toloza EM, Jacobs DO. Myocellular creatine transporter

function is modulated by changes in its phosphorylation status. Society of Black Academic Surgeons 2006.

A60. Darrabie MD, Santacruz-Toloza L, Goers L, Toloza EM, Jacobs DO. Myocellular creatine

transporter is modulated by phosphorylation. Duke University School of Medicine Alpha Omega Alpha Research Symposium 2006.

A61. Darrabie MD, Santacruz-Toloza L, Goers L, Toloza EM, Jacobs DO. AMPK activation increases

activity of the creatine transporter expressed in an immortalized adult cardiac cell line. Biophysical Society 2007.Creatine Tr

44

A62. Darrabie MD, Zhao Z, Goers L, Santacruz-Toloza L, Toloza EM, Jacobs DO. Creatine transport is modulated by PKC and PP1/PP2A. Biophysical Society 2007.

A63. Darrabie MD, Cachau RE, Santacruz-Toloza L, Jacobs DO. Doxorubicin decreases creatine

transport in HL-1 cardiac myocytes expressing the human creatine transporter. Joint Biophysical Society 52nd Annual Meeting and the 16th International Biophysics Congress 2008.

A64. Nienaber J, Hernandez A, Goers L, Toloza EM, Mao L, Rockman HA, Santacruz-Toloza L, Jacobs

DO. Cardiac overexpression of the creatine transporter depletes ATP and ADP and alters cardiac function. Joint Biophysical Society 52nd Annual Meeting and the 16th International Biophysics Congress 2008.

A65. Alexis M, Prince-Petersen R, Jacobs DO, Clary B, Pryor A. Intern boot camp: One day makes a

difference. Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting 2009.

A66. Scarborough JE, Bennett KM, Swedish TB, Schroeder RA, Jacobs DO, Kuo PC. Will the clinicians support the researchers and teachers? Results of a salary satisfaction survey of 1,038 academic surgeons. American Surgical Association 129th Annual Meeting 2009.

A67. Darrabie MD, Mishra R, Cachau RE, Santacruz L, Jacobs DO. Doxorubicin decreases creatine

transport in cardiomyocytes. Society of Black Academic Surgeons 20th Annual Meeting 2010.

A68. Arciniegas AJL, Santracruz L, Jacobs DO. Creatine depletion does not upregulate creatine transport in CaCo-2 cells. Society of Black Academic Surgeons 20th Annual Meeting 2010.

A69. Worni M, Ostbye T, Shah J, Rajgor D, Jacobs DO, Pietrobon R, Guller U. Laparoscopic

appendectomy is as safe for patients admitted on weekends as for those admitted on weekdays: A national study on 146,088 patients. 98th Annual Congress of the Swiss Society of Surgery. May 26, 2011. Poster Presentation.

A70. Worni M, Ostbye T, Rajgor D, Shah J, Jacobs DO, Pietrobon R, Guller U. Concomitant cholecystectomy in laparoscopic gastric bypass surgery is decreasing: A national study of 69,182 patients. 98th Annual Congress of the Swiss Society of Surgery. May 27, 2011. Podium Presentation.

A71. Santacruz-Toloza L, Darrabie M, Mishra R, Jacobs DO. What are the structural determinants of creatine transport regulation? Biophys J 2009 96 (3):686a.

A72. Hernandez A, Pinilla A, Nienaber J, Mao L, Rockman H, Santacruz L, and Jacobs DO. Increased intracellular creatine content is not harmful to the mouse heart. FASEB J March 17, 2011 25:1033.10.

A73. Arciniegas, J, Jacobs DO, and Santacruz L. Creatine transport in cardiomyocytes and C2C12 cells FASEB J March 17, 2011 25:1033.11.

A74. Mantilla JG, Jacobs DO, and Santacruz L. Verapamil and dantrolene inhibit creatine transport in skeletal and cardiac myocytes. FASEB J March 17, 2011 25:657.10.

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A75. Santacruz L, Darrabie MD, Mishra R, Arciniegas J, Pinilla M, and Jacobs DO. Doxorubicin disruption of creatine transport in cardiomyocytes is prevented by PP1A/PP2 inhibition. FASEB J March 17, 2011 25:1033.7.

A76. Pinilla M, Jacobs DO, and Santacruz L. Norepinephrine stimulates creatine transporter activity in cardiomyocytes via {beta}-adrenergic activation: implications for heart failure energetics. FASEB J March 17, 2011 25:1033.8.

A77. Arciniegas J, Jacobs DO, Santacruz L. Hypoxia decreases creatine transport in cardiomyocytes and C2C12 cells. The FASEB Journal. 2011;25(1_supplement):1033.11-.11.

A78. Darrabie M, Arango J, Mishra R, Santacruz, Jacobs DO. Creatine blunts doxorubicin-induced cardiomyocellular injury. Society of Black Academic Surgeons 22nd Annual Meeting 2012. Claude Organ Research Award Recipient.

A79. Darrabie M, Mantilla JG, Jacobs DO, Santacruz L. Creatine supplementation ameliorates doxorubicin mediated cytotoxicity. American Surgical Congress, Las Vegas, NV, February 14-16, 2012.

A80. Santacruz L, Arcinieas AJL, Darrabie M, Mantilla JG, Baron RM, Bowles DE, Mishra R, Jacobs DO. Hypoxia decreases creatine uptake in cardiomyocytes, while creatine supplementation enhances HIF activation. Physiol Rep 2017 (5) e13382, https://doi.org/10.14814/phy2.13382.

Non-Print Materials

1. Jacobs DO. Newton's Apple, PBS's award-winning family science program, "Appendix Chat" segment. Show #712, December 24, 1989.

2. Jacobs DO, Robinson MK. Massive Intestinal Resection. Medical Outlook/Portfolio, Cortlandt

Group, Inc. 1996.

3. Jacobs DO. Clinical supervising consultant. Computer Assisted Instruction for Critical Care/Emergency Medicine, “Sim Coeur”, NEC Corporation 1996.

4. Jacobs, DO. People’s Pharmacy, NPR program, “Diverticulitis” 2007.

5. Jacobs DO. (Editor) Procedures Consult: General Surgery Module.

www.proceduresconsult.com/medical-procedures/general-surgery-specialty.aspx. Elsevier 2010.