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Cytokines IL1 fever IL2 stimulate T cells IL3 stimulate bone marrow IL4 IgE and IgG IL5 IgA and eosinophils IL6 an acute phase reactant, comes from macrophages ( like IL1) INF Alpha: an acute phase reactant, comes from macrophages. Mediates septic shock. IL8: from macrophage. Major chemotactic factor ( the I in the nemonic click. IL10: induces Th2 and inhibits Th1 IL12: induces the differentiation of T cells into T helper 1 cells. Activates macrophages INF gamma: activates macrophages

Cytokine s

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Cytokine s

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Cytokines

IL­1 feverIL­2 stimulate T cellsIL­3 stimulate bone marrowIL­4 IgE and IgGIL­5 IgA and eosinophilsIL­6 an acute phase reactant, comes from macrophages ( like IL­1)INF Alpha: an acute phase reactant, comes from macrophages.Mediates septic shock.IL­8: from macrophage. Major chemotactic factor ( the I in thenemonic click.IL­10: induces Th­2 and inhibits Th­1IL­12: induces the differentiation of T cells into T helper 1 cells.

Activates macrophagesINF gamma: activates macrophages