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Day 1– Wednesday 1 st July [PLB-D Floor (D05, D06, D07)] Last updated: 22/06/2015 01:47:49 POSTER TIMETABLE Day 1 – Wednesday 1st July [PLB-D Floor (D05, D06, D07)] Poster number Poster topic Presenters Group Presentation type 1. A mechanistic understanding of granule breakage in continuous twin screw granulation J. G. Osorio 1 , R. Sayin 1 & J. D. Litster 1,2 1 Department of Chemical Engineering, Purdue University, USA 2 Department of Industrial and Physical Pharmacy, Purdue University, USA Poster only 2. A robustness study of an extended-release tablet formulation using a sample kit of Hypromellose for QbD concept S. Mistry 1 , T. Hoshino 2 & H. Kokubo 2 1 Shin-Etsu Pharma & Food Materials Distribution GmbH, Germany 2 Shin-Etsu Chemical Co., Ltd., Cellulose Technical Support Center, Japan Poster only 3. A theoretical study of the hydrodynamic behaviour of fluidized beds operated under reduced pressure S. Zarekar 1 , F. Sondej 1 , A. Bück 1 , E. Tsotsas 1 & M. Jacob 2 1 Thermal Process Engineering, Otto von Guericke University Magdeburg, Germany 2 Glatt Ingenieurtechnik GmbH, Germany Poster only 4. Analysis of a twin-screw granulation process using a combined experimental and computational approach A. Kumar 1,2 , J. Vercruysse 3 , K. V. Gernaey 4 , T. De Beer 2 & I. Nopens 1 1 BIOMATH, Ghent University, Belgium 2 Laboratory of Pharmaceutical Process Analytical Technology, Ghent University, Belgium 3 Laboratory of Pharmaceutical Technology, Ghent University, Belgium 4 CAPEC-PROCESS, Technical University of Denmark, Denmark Poster only 5. Analysis of meso-scale effects in high shear granulation through a CFD-PBM coupled compartment model P. J. Abrahamsson 1 , P. Kvist 1 , X. Yu 2 , G. Reynolds 3 , I. Björn Niklasson 4 & A. Rasmuson 1 1 Chalmers University of Technology, Sweden 2 Aston University, UK 3 Pharmaceutical and Analytical Research and Development, AstraZeneca, UK 4 AstraZeneca Pharmaceutical Development R&D Mölndal, Sweden Poster only 6. Applicability of the Ryshkewitch- Duckworth equation on direct and dry granule compression J. Mosig & P. Kleinebudde Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine- University, Germany Poster only 7. Caking of complex sucrose mixtures S. Samain, M. Benali, M. Leturia, E. V. Hecke, I. Pezron & K. Saleh UTC/ESCOM, Equipe d’Accueil "Transformations Intégrées de la Matière Renouvelable" (EA 4297), France Poster only

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Day 1– Wednesday 1st July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

POSTER TIMETABLE

Day 1 – Wednesday 1st July [PLB-D Floor (D05, D06, D07)] Poster number

Poster topic Presenters Group Presentation type

1. A mechanistic understanding of granule breakage in continuous twin screw granulation

J. G. Osorio1, R. Sayin1 & J. D. Litster1,2

1 Department of Chemical Engineering, Purdue University, USA 2 Department of Industrial and Physical Pharmacy, Purdue University, USA

Poster only

2. A robustness study of an extended-release tablet formulation using a sample kit of Hypromellose for QbD concept

S. Mistry1, T. Hoshino2 & H. Kokubo2

1 Shin-Etsu Pharma & Food Materials Distribution GmbH, Germany 2 Shin-Etsu Chemical Co., Ltd., Cellulose Technical Support Center, Japan

Poster only

3. A theoretical study of the hydrodynamic behaviour of fluidized beds operated under reduced pressure

S. Zarekar1, F. Sondej1, A. Bück1, E. Tsotsas1 & M. Jacob2

1 Thermal Process Engineering, Otto von Guericke University Magdeburg, Germany 2 Glatt Ingenieurtechnik GmbH, Germany

Poster only

4. Analysis of a twin-screw granulation process using a combined experimental and computational approach

A. Kumar1,2, J. Vercruysse3, K. V. Gernaey4, T. De Beer2 & I. Nopens1

1 BIOMATH, Ghent University, Belgium 2 Laboratory of Pharmaceutical Process Analytical Technology, Ghent University, Belgium 3 Laboratory of Pharmaceutical Technology, Ghent University, Belgium 4 CAPEC-PROCESS, Technical University of Denmark, Denmark

Poster only

5. Analysis of meso-scale effects in high shear granulation through a CFD-PBM coupled compartment model

P. J. Abrahamsson1, P. Kvist1, X. Yu2, G. Reynolds3, I. Björn Niklasson4 & A. Rasmuson1

1 Chalmers University of Technology, Sweden 2 Aston University, UK 3 Pharmaceutical and Analytical Research and Development, AstraZeneca, UK 4 AstraZeneca Pharmaceutical Development R&D Mölndal, Sweden

Poster only

6. Applicability of the Ryshkewitch-Duckworth equation on direct and dry granule compression

J. Mosig & P. Kleinebudde Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-University, Germany

Poster only

7. Caking of complex sucrose mixtures

S. Samain, M. Benali, M. Leturia, E. V. Hecke, I. Pezron & K. Saleh

UTC/ESCOM, Equipe d’Accueil "Transformations Intégrées de la Matière Renouvelable" (EA 4297), France

Poster only

Day 1– Wednesday 1st July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

8. CFD simulation of particle residence time distribution in multistage fluidized beds

K. Chen1, L. Mielke1, A. Bück1, M. Jacob2 & E. Tsotsas1

1 Thermal Process Engineering, Otto von Guericke University Magdeburg, Germany 2 Glatt Ingenieurtechnik GmbH, Germany

Poster only

9. Characterization of indomethacin microparticles for inhalatory administration

N. E. Ceschan, L. C. Gallo, V. Bucalá & M. V. Ramírez-Rigo

Planta Piloto de Ingeniería Química (PLAPIQUI), CONICET- Universidad Nacional del Sur (UNS), Argentina

Poster paper

(70)

10. Comparative study of matrix tablets - effect of the granulation method

A. Sauer1, M. Fukusawa2 & T. Hoshino2

1 Shin-Etsu Pharma & Food Materials Distribution GmbH, Germany 2 Shin-Etsu Chemical Co., Ltd. Cellulose Technical Support Center, YBP Technical center, Japan

Poster only

11. Comparison of excipient only & drug formulations for twin-screw continuous granulator

I. P. Gabbott, A. Khan & G. K. Reynolds

Pharmaceutical Development, AstraZeneca, UK Poster only

12. Computational fluid dynamic simulation of a perforated rotating bucket: an industrial case study

N. Rahmanian1, S. Verdier1,2, E. Jarry1,2 & P.Olley1

1 School of Engineering and Informatics, University of Bradford, 2 UK CESI Saint-Nazaire (Engineering School), France

Poster paper

(71)

13. Continuum modeling of dense and dilute particle flows in high shear granulation

M. Khalilitehrani, E. Fino, P. J. Abrahamsson & A. Rasmuson

Department of Chemical Engineering, Chalmers University of Technology, Sweden

Poster only

14. Eliminating bi-modal PSD’s in a continuous twin screw wet granulation process

J. Holman1 & T. Van Hoek2 1 Process Development Group, GEA Pharma Systems Ltd, UK 2 Process Development Centre, GEA Pharma System nv, Belgium

Poster only

15. De-mixing characteristics of fine coal in an air dense medium fluidized bed

P. Zhao1, Y. Zhao2, Z. Luo2 & R. Zhu1

1 School of Electric Power Engineering, China University of Mining and Technology, China 2 School of Chemical Engineering and Technology, China University of Mining and Technology, China

Poster paper

(72)

16. Development and characterization of ternary solid dispersion granules: prediction of glass transitions

A. B. Albadarin1,2, J. A. Collins1, M. Davis1, D. Egan1, C. Mangwandi2, M. Southern1 & G. Walker1,2

1 Department of Chemical and Environmental Sciences, University of Limerick, Ireland 2 School of Chemistry & Chemical Engineering, Queens University Belfast, UK

Poster only

Day 1– Wednesday 1st July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

17. Effect of colloidal silica dioxide on rheological properties of common pharmaceutical excipients

D. Majerová1, L. Kulaviak2, M. Růžička2 & F. Štepanek3

1 Department of Organic Technology, Institute of Chemical Technology, Czech Republic 2 Institute of Chemical Process Fundamentals of the ASCR, Czech Republic 3 Department of Chemical Engineering, Institute of Chemical Technology, Czech Republic

Poster paper

(73)

18. Effect of food/microorganism (f/m) ratio on granular sludge characteristics in sbr system

M. Sajjad1,2 & K. S. Kim1,2 1 Korea University of Science and Technology, Republic of Korea 2 Korea Institute of Civil Engineering and Building Technology, Republic of Korea

Poster only

19. Effect of polymers on the stability of anhydrous olanzapine during processing

M. Paisana1, M. Wahl2 & J. F. Pinto1

1 iMed – Research Institute for Medicines and Pharmaceutical Sciences, Universidade de Lisboa, Portugal 2 Pharmazeutisches Institut, Eberhard Karls Universität Tübingen, Germany

Poster only

20. Effects of binder addition politics on the wet agglomeration process

S. Nalesso1, E. Franceschinis2, N. Realdon2 & A. C. Santomaso1

1 Advanced Particle Technology Laboratory Department of Industrial Engineering University of Padova, Italy 2 Department of Pharmaceutical and Pharmacological Science, University of Padua, Italy

Poster paper

(74)

21. Effects of water quantity on tablets properties made by high shear granulation with l-HPC

A. Sauer1, M. Fukasawa2 & N. Maruyama3

1 SE-PFMD, Germany 2 Shin Etsu Chemical Co., Ltd, Cellulose Technical Support Center, Japan 3 Shin Etsu Chemicals Co., Specialty Research Center, Japan

Poster only

22. Modelling framework for the dynamic flowsheet simulation of solids processes

V. Skorych, E. Eichner, M. Dosta, E. Hartge & S. Heinrich

Hamburg University of Technology, Germany Poster paper

(75)

23. FEM study of different roll compactor sealing system design

A. Mazor, L. Perez-Gandarillas, A. Michrafy & A. deRyck

Mines Albi, CNRS, Universitè de Toulouse, France Poster only

24. Fluid-bed melt granulation: growth regime prediction

M. Villa, I. Cotabarren, D. Bertín, J. Piña & V. Bucalá

Department of Chemical Engineering, Universidad Nacional del Sur, CONICET, Argentina

Poster paper

(76)

Day 1– Wednesday 1st July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

25. Fluidized bed coating control by in-line particle size measurement

D. Wiegel1, G. Eckardt2, M. Jacob3, M. Scharmer4, I. Schellenberg4 & B. Wolf1

1 Department of Applied Biosciences and Process Engineering, Anhalt University of Applied Sciences, Germany 2 Parsum GmbH, Germany 3 Glatt Ingenieurtechnik GmbH, Germany 4 Institute of Bioanalytical Sciences, University of Applied Sciences, Germany

Poster paper

(77)

26. Fluidized-bed melt granulation: population balance modelling to identify the aggregation kernel

M. Villa, D. Bertín, I. Cotabarren, J. Piña & V. Bucalá

Department of Chemical Engineering, Universidad Nacional del Sur, CONICET, Argentina

Poster only

27. Formulation and evaluation of methacrylic and poly (acrylic) acid matrix tablets of mebendazole for colon targeted delivery

J. E. Okorie, F.N. Uba, O. N. C Umeh & S. I. Ofoefule

Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nigeria

Poster paper

(78)

28. Gaining process knowledge by using mechanistic models for fluidized bed drying in a continuous manufacturing environment

S. T.F.C. Mortier1, K. V. Gernaey2, T. De Beer2 & I. Nopens3

1 BIOMATH, Ghent University, Belgium 2 Laboratory of Pharmaceutical Process Analytical Technology, Ghent University, Belgium 3 CAPEC-PROCESS, Technical University of Denmark, Denmark

Poster only

29. Impact of screw configuration on the particle size distribution of granules produced by twin screw granulation

J. Vercruysse1, A. Burggraeve2, M. Fonteyne3, P. Cappuyns4, U. Delaet5, I. Van Assche5, T. De Beer3, J.P. Remon1 & C. Vervaet1

1 Department of Pharmaceutics, Ghent University, Belgium 2 Department of Analytical Development, Janssen Pharmaceutica, Belgium 3 Department of Pharmaceutical Analysis, Ghent University, Belgium 4 Global Technical Services, Janssen Pharmaceutica, Belgium 5 Department of Pharmaceutical Development, Janssen Pharmaceutica, Belgium

Poster only

30. Implementation of roller compaction into a continuous manufacturing environment

K. A. Overhoff, V. Dhamankar & C. Metzler

Vertex Pharmaceuticals Incorporated, USA Poster only

31. Influence of modified wurster draft tube on coating uniformity of pellets

M. Luštrik & R. Dreu Department of Pharmaceutical Technology, University of Ljubljana, Slovenia

Poster paper

(79)

Day 1– Wednesday 1st July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

32. Influence of nozzle configuration on process stability of continuous fluidized bed layering with external classification

A. Bück1, K. Meyer1, S. Palis2, C. Neugebauer3, A. Kienle2,3, S. Heinrich4 & E. Tsotsas1

1 Chair of Thermal Process Engineering, Otto von Guericke University Magdeburg, Germany 2 Chair of Automation and Modelling, Otto von Guericke University Magdeburg, Germany 3 Max Planck Institute for Dynamics of Complex Technical Systems, Germany 4 Solids Process Engineering, Hamburg University of Technology, Germany

Poster paper

(80)

33. Influence of process parameters and mechanical properties of pharmaceutical materials on milling of roller compacted ribbons

A. Mirtic & G. Reynolds Pharmaceutical Development, AstraZeneca, UK Poster only

34. Influence of the pelletizing process parameters on the mechanical properties of the received alumina oxide pellets

Z. Radeva, P. Müller & J.Tomas Institute of Process Engineering, Otto von Guericke University Magdeburg, Germany

Poster only

35. Influence of the solid bond model on an irregular shaped agglomerate behaviour in DEM simulations

S. Kozhar1, M. Dosta1, V. Salikov1, S. Antonyuk2 & S. Heinrich1

1 Institute of Solids Process Engineering and Particle Technology, Hamburg University of Technology, Germany 2 Chair of Particle Process Engineering, University of Kaiserslautern, Germany

Poster only

36. Inline particle size measurement in roll compaction/dry granulation

H. A. Mangal & P. Kleinebudde Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-University, Germany

Poster only

37. Kinetics of immersion nucleation driven by surface tension

K. Pitt1, R. Smith1, M. J. Houslow1, J. D. Litster2

1 University of Sheffield, UK 2 Purdue University, USA

Poster paper

(81)

38. Liquisolid technology applied to pellets

B. R. Pezzini1, 2, A. O. Beringhs3, H. G. Ferraz1, M. A. Segatto Silva3, H. K. Stulzer3 & D. Sonaglio3

1 Faculty of Pharmaceutical Sciences, University of São Paulo, Brazil 2 Department of Pharmacy, University of Joinville Region, Brazil 3 Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Brazil

Poster paper

(82)

Day 1– Wednesday 1st July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

39. Manufacturing and mechanical testing of briquettes from inertinite-rich high ash coal fines using various binders

N. T. Modiri1, J. R. Bunt1, 2, H. W. J .P. Neomagus1 & F. B. Waanders1

1 School of Chemical and Minerals Engineering, North-West University, South Africa 2 Sasol Technology (PTY) Ltd., South Africa

Poster only

40. Measurement & quantification of caking in powders

T. Freeman, J. Clayton, K. Brockbank & D. Millington Smith

Freeman Technology, UK. Poster paper

(83)

41. Mechanistic time scales in adhesive particle mixing

D. Nguyen1, A. Rasmuson1, I. N. Björn2 & K. Thalberg2

1 Department of Chemical Engineering, Chalmers University of Technology, Sweden 2 AstraZeneca Pharmaceutical Development R&D Mölndal, Sweden

Poster only

42. Micromeritic, granulating and dissolution properties of rice starch in metronidazole based formulations

O.N.C Umeh, K.C Ezeagwu & S.I Ofoefule

Department of Pharmaceutical Technology and Industrial Pharmacy, University of Nigeria, Nigeria

Poster paper

(84)

43. Magnetic particle tracking: analysis of the particle motion in rotor based granulation equipment

J. Neuwirth & S. Heinrich Institute of Solids Process Engineering and Particle Technology, Hamburg University of Technology, Germany

Poster only

44. Model predictive control of continuous mechanochemical synthysis based on self-sustaining reactions

A. B. Albadarin1,2, C. Griffin, M. Davis1, D. Egan1 & G. Walker1,2

1 Chemical & Environmental Sciences, University of Limerick, Ireland 2 School of Chemical Engineering, Queen’s University Belfast, UK

Poster only

45. New insights in scale up of spheronization process

D. Thaete, E. Reitz & M. Thommes

Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-University, Germany,

Poster only

46. On the role of porosity for the compressibility and tablet tensile strength of granules prepared by dry and wet granulation

J. Nordström & G. Alderborn Department of Pharmacy, Uppsala University, Sweden Poster only

47. Population balance modeling of spray granulation in horizontal fluidized beds

K. Meyer, R. Pashminehazar, A. Bück & E. Tsotsas

Chair of Thermal Process Engineering, Otto von Guericke University Magdeburg, Germany

Poster only

Day 1– Wednesday 1st July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

48. Predicting the surface composition of a spray dried particle by modelling component reorganization in a drying drop

A. Porowska1, M. Dosta1 A. Gianfrancesco2, L. Fries3, S. Palzer4 & S. Heinrich1

1 Hamburg University of Technology, Germany 2 Nestlé Product Technology Center Konolfingen, Switzerland 3 Nestlé Research Center Lausanne, Switzerland 4 Nestlé Beverages Business Unit, Switzerland

Poster paper

(85)

49. Preparation and characterization of adsorbents by granulation and extrusion

E. Goldnik, Y. Lopéz, R. Plätzer, B. Lamprecht, C. Eichler, T. Thiripuvanam & T. Turek

Institute of Chemical and Electrochemical Process Engineering, Clausthal University of Technology, Germany

Poster only

50. Quantifying tablet punch adhesion risk using a compaction simulator

M. Hoque1, E. Harrop Stone1, D.Wilkes2 & V. Wilkes2

1 Merlin Powder Characterisation Ltd, UK 2 Phoenix Calibration and Services Ltd, UK

Poster only

51. Reduction of energy consumption in batch fluidized bed layering granulation processes by temporal separation

L. Mielke1, T. Hoffmann1, M. Peglow2, M. Henneberg3, A. Bück1 & E. Tsotsas1

1 Thermal Process Engineering/NaWiTec, Otto von Guericke University Magdeburg, Germany 2 IPT Pergande GmbH, Germany 3 AVA GmbH, Germany

Poster paper

(86)

52. Roller compactor: mechanical property of pre-compacted body

R. B. Al Asady, R. M. Dhenge, M. J. Hounslow & A. D. Salman

Department of Chemical and Biological Engineering, University of Sheffield, UK

Poster Paper

(87)

53. Solid crystal suspensions - an advanced formulation strategy for poorly water soluble drugs

E. Reitz1, C. Vervaet2, S. Weidtkamp-Peters3 & M. Thommes1

1 Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-University, Germany 2 Laboratory of Pharmaceutical Technology, Ghent University, Belgium 3 Center for Advanced Imaging, Heinrich-Heine-University, Germany

Poster only

54. Stochastic modeling of layering growth processes in fluidized beds

C. Rieck, A. Bück & E. Tsotsas NaWiTec, Thermal Process Engineering, Otto von Guericke University Magdeburg, Germany

Poster paper

(88)

55. The compression behavior of binary and ternary excipient blends of different mechanical properties

F. Al-akayleh1, I. Rashid2, M. Al-Omari2, M. Shubair1, A. Badwan2

1 Department of Pharmaceutics and Pharmaceutical Technology, Petra University, Jordan 2 The Jordanian Pharmaceutical Manufacturing Company, Jordan

Poster paper

(89)

Day 1– Wednesday 1st July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

56. The effects of compression speed, punch shape and wall friction on thermomechanical behaviour of powders during compression

A. Krok1,2, M. Peciar2 & C. Y. Wu1

1 Department of Chemical and Process Engineering, University of Surrey, UK 2 Department of Chemical and Hydraulic Machines and Equipment, Slovak University of Technology, Slovakia

Poster only

57. The importance of mixing vessel configurations on the dispersion of food powders in water

W. R. Mitchell1, 2, L. Forny3, T. O. Althaus4, G. Niederreiter2, S. Palzer1, 5, M. J. Hounslow1 & A. D. Salman5

1 Department of Chemical and Biological Engineering, University of Sheffield, UK 2 Nestlé Product Technology Center- Orbe, Switzerland 3 Nestlé Research & Development, Singapore 4 Nestlé Product Technology Center- York, UK 5 Nestlé Corporate Headquarters, Switzerland

Poster only

58. The influence of manufacturing method on physical properties and drug release from push pull osmotic pump (PPOP) products

M. Ghimire1, G. LaBella2, M. Rane2 & P. Patel2

1 Colorcon Ltd., UK 2 Colorcon, Inc., USA

Poster paper

(90)

59. The interdependency of material, process and equipment parameters for extrusion-spheronisation formulations

J. A. Collins1, A. B. Albadarin2, M. T. Davis2, D. Egan3, C. S. Griffin2 & G. M. Walker1,2,4

1 Pharmaceutical Manufacturing Technology Centre, University of Limerick, Ireland 2 Synthesis and Solid State Pharmaceutical Cluster, University of Limerick, Ireland 3 Enterprise Research Centre, University of Limerick, Ireland 4 School of Chemistry and Chemical Engineering, Queens University Belfast, UK

Poster only

60. Twin screw wet granulation: Effect of types of powders

R. M. Dhenge1, S. V. Lute1, C. S. Omar1, M. F. Saleh1, J. J. Cartwright2, M. J. Hounslow1 & A. D. Salman1

1 Department of Chemical and Biological Engineering, University of Sheffield, UK

2 GSK, UK

Poster only

61. Understanding the influence of granule microstructure on granule compression breakage

S. A. Dale1, M. Dosta2, S. Antonyuk3, C. Wassgren1, S. Heinrich2 & J. D. Litster1

1 Purdue University, USA 2 Hamburg University of Technology, Germany 3 University of Kaiserslautern, Germany

Poster paper

(91)

62. Use of Multieye, an in-line NIR based PAT solution for real-time, non-product content monitoring of moisture contents in a fluidised bed granulation/drying process

P. Cruise1, L. Kiernan1, D. Byrne1, I. Jones1, D. Togashi2

1 Innopharmalabs, Ireland 2 Dublin Institute of Technology (DIT), Ireland

Poster only

Day 1– Wednesday 1st July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

63. Roller compaction: effect of morphology and amorphous content of lactose on product quality

C. S. Omar1, R. M. Dhenge1, J. D. Osborne2, Tim Althaus2, S. Palzer3, M. J. Hounslow1 & A. D. Salman1

1 Department of Chemical and Biological Engineering, University of Sheffield, UK 2 Nestle´ Product Technology Centre York, UK 3 Nestlé SA Headquarters, Switzerland

Poster only

Day 2– Thursday 2nd July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

POSTER TIMETABLE

Day 2 – Thursday 2nd July [PLB-D Floor (D05, D06, D07)] Poster number

Poster topic Presenters Group Presentation type

64. A proposal for a drug product manufacturing classification system (MCS) for oral solid dosage forms

M. Leane1, K. Pitt2 & G. Reynolds3

1 Bristol-Myers Squibb, UK 2 GlaxoSmithKline, UK 3 AstraZeneca, UK

Poster only

65. Advanced characterisation and modelling to predict iron ores granulation behaviour

R. J. Contreras1, F. Van Loo1, M. Evrard2, M. Schöngut3, E. Pirard2 & F. Štěpánek3

1 Centre for Research in Metallurgy, Belgium 2 Department of Chemical Engineering, Institute of Chemical Technology Prague, Czech Republic 3 Department Génie Minéral, University of Liège, Belgium

Poster only

66. Application of the Eyecon, an in-line non product contact process analytical technology to perform particle characterisation during fluidised bed processes

P. Cruise1, E. Hogan1, I. Jones1, S. Banahan1, C. Cortazzo2, J. Fröhlich2, L. Sprich2, R. Pila2

1 Innopharmalabs, Ireland 2 Glatt GmbH, Process Technology, Germany

Poster only

67. Assessment of wetting and dispersing measurements of dairy powders and the agglomerates

J. Ji1,2, J. Fitzpatrick2, K. Cronin2, A. Crean3 & S. Miao1

1 Teagasc Food Research Centre, Ireland 2 School of Engineering, University College Cork, Ireland 3 School of Pharmacy, University College Cork, Ireland

Poster only

68. Compartmental approach to wet granulation models within a flowsheeting framework

D. A. Pohlman1, D. Slade3, S. Bermingham3, M. Bollinger4, P. Bach4 & J. D. Litster1,2

1 Department of Chemical Engineering Purdue University, USA 2 Department of Industrial and Physical Pharmacy, Purdue University, USA 3 Process Systems Enterprise Limited, Process Systems Enterprise Limited, UK 4 Novozymes A/S, Denmark

Poster only

69. Compressive strength of pharmaceutical pellets spray coated in a wurster fluidized bed

A. Russell1, R. Šibanc2, P. Müller1, R. Dreu2 & J. Tomas1

1 Chair for Mechanical Process Engineering, Otto von Guericke University Magdeburg, Germany 2 Chair for Pharmaceutical Technology, Faculty of Pharmacy, University of Ljubljana, Slovenia

Poster only

Day 2– Thursday 2nd July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

70. Coupled gas flow and powder deformation under roller compaction

A. Michrafy, L. Prerez Gandarillas, A. Mazor

Mines Albi, CNRS, Université de Toulouse, France Poster only

71. Determination of compartment residence times within batch granulators using colorimetric analysis

A. D. McGuire, S. Mosbach, K. F. Lee & M. Kraft

Department of Chemical Engineering and Biotechnology, University of Cambridge, UK

Poster only

72. Development of a controlled release formulation by continuous twin screw granulation

V. Vanhoorne1, J. Vercruysse1, F. De Leersnyder2, T. De Beer2 J. P. Remon1 & C. Vervaet1

1 Laboratory of Pharmaceutical Technology, Ghent University, Belgium 2 Laboratory of Pharmaceutical Process Analytical Technology, Ghent University, Belgium

Poster only

73. Evaluation of a new co-processed excipient for orally-disintegrating tablets

S. Mistry1, Y. Hirama2, S. Obara2 & N. Maruyama2

1 Shin-Etsu Pharma & Food Materials Distribution GmbH, Germany 2 Shin-Etsu Chemical Co., Ltd., Shin-Etsu Chemical Co., Ltd. Cellulose Technical Support Center, Japan

Poster only

74. Effect of varying process parameters on granule size distribution of roll compacted mcc, mannitol and their mixtures

A. Pérez Gago & P. Kleinebudde

Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-University, Germany

Poster only

75. Effect of varying volume of a secondary immiscible liquid on the movement within a suspension

S. F. Islam1, S. Whitehouse2, R. V. Sundara2, T. O. Althaus2, S. Palzer3, M. J. Hounslow1 & A. D. Salman1

1 Department of Chemical and Biological Engineering, University of Sheffield, UK 2 Nestlé PTC York, UK 3 Nestlé Headquarters, Switzerland

Poster only

76. Evaluation of the granulation process using flow and particle size analysis parameters

E. J. Barbosa, N. V. Souza, L. Giorgetti, M. D. Duque, M. G. Issa & H. G. Ferraz

Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of São Paulo, Brazil

Poster only

77. Experimental investigation of process stability of continuous spray fluidized bed layering processes

M. Schmidt, C. Rieck, A. Bück & E. Tsotsas

NaWiTec, Thermal Process Engineering, Otto von Guericke University Magdeburg, Germany

Poster only

Day 2– Thursday 2nd July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

78. Fabricating of hierarchically assembled ceramic-polymer composites using a spouted bed spray granulation process

E. Eichner1, S. Heinrich1, M. F. H. Wolff1, G. A. Schneider2 & S. Antonyuk3

1 Institute of Solids Process Engineering and Particle Technology, Hamburg University of Technology, Germany 2 Institute of Advanced Ceramics, Hamburg University of Technology, Hamburg University of Technology, Germany 3 Department of Mechanical and Process Engineering, University of Kaiserslautern, Germany

Poster only

79. Formulation development, characterization and evaluation of liquisolid tablet containing orlistat

S. Gaikwad, M. Tajne & N. Gaikwad

University Department of Pharmaceutical Sciences, RTM Nagpur University, India

Poster paper

(92)

80. Estimation of the energy required for drying of digestate granular fertilizer granulation plant using aspen plus

E. Stuart, Y. F. Glocheux, M. R. Mendes de Araújo, A. B. Albadarin & C. Mangwandi

School of Chemistry and Chemical Engineering, Queen's University Belfast, UK

Poster Paper

(93)

81. High shear granulation processing parameters on the mechanical properties of diatomite based porous granulates (for the macro scale i: processing for granulation)

Y. Liu, D. Scharf, T. Graule & F. Clemens

EMPA, Swiss Federal Laboratories for Materials Science and Technology, Switzerland

Poster only

82. Influence of excipient material properties on a dry granulation process

M. E. Crowley1,2, G. E. O Mahony1,2 M. A.P. McAuliffe3, R. C. Dontireddy1 & A. M. Crean1,2

1 School of Pharmacy, University College Cork, Ireland 2 Synthesis and Solid State Pharmaceutical Centre, Ireland 3 Centre for Advanced Photonics and Process Analysis Cork Institute of Technology, Cork

Poster only

83. Innovative granulated materials from industrial and organic wastes as sorbents for wastewater treatment

E. Iakovleva1,2, M. Sillanpää1, P. Maydannik1, S. Allen2, A. B. Albadarin2,3 & C. Mangwandi2

1 Laboratory of Green Chemistry, Lappeenranta University of Technology, Finland 2 School of Chemistry and Chemical Engineering, Queen's University Belfast, UK 3 Department of Chemical and Environmental Science, University of Limerick, Ireland

Poster only

Day 2– Thursday 2nd July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

84. Investigation of the axial particle transport in a continuously operated horozontal fluidized bed

E. Diez & S. Heinrich Institute of Solids Process Engineering and Particle Technology, Hamburg University of Technology, Germany

Poster only

85. Mechanochemical synthysis of hydroxyapatite employing high and low shear milling processes

A. B. Albadarin1,2, C. Griffin, M. Davis1, D. Egan1 & G. Walker1,2

1 Chemical & Environmental Sciences, University of Limerick, Ireland 2 School of Chemical Engineering, Queen’s University Belfast, UK

Poster only

86. Modeling granulation behavior in an agitated filter dryer

A. Tamrakar1, A. Gunadi2, P. M. Piccione2 & R. Ramachandran1

1 Department of Chemical and Biochemical Engineering, The State University of New Jersey, USA 2 Process Studies Group, Technology & Engineering, Syngenta Ltd., United Kingdom

Poster only

87. Investigation of the granular dispersion behaviour in a fluid bed rotor processor

J. Neuwirth & S. Heinrich Institute of Solids Process Engineering and Particle Technology, Hamburg University of Technology, Germany

Poster only

88. Modelling of particle-air interactions during flow into closed cavities

H. Elmsahli, A. Alharbi, R. Baserinia and I. C. Sinka

Department of Engineering, University of Leicester, UK Poster only

89. Novel electrostatic ionizer for charged polypropylene granules

K. Choi1, T. Mogami2, T. Suzuki2 & M. Yamaguma1

1 Japan National Institute of Occupation Safety and Health, Japan 2 Kasuga Denki, Japan

Poster only

90. Practical application of unified compaction curve to roller compaction formulation design and equipment transfer

G. K. Reynolds, R. J. Roberts, S. Claxton, A. Mirtic & J. Parry

Pharmaceutical Development, AstraZeneca, UK Poster only

91. Creating tuneable agglomerates via 3D printing

R. Ge1, M. Ghadiri2 & K. Hapgood1

1 Monash Advanced Particle Engineering Laboratory, Monash University, Australia 2 Institute of Particle Science and Engineering, University of Leeds, UK

Poster only

92. Protective effect of sugars on the viability of Lactobacillus Rhamnosus gg after spray-drying

G. AM. Broeckx & F. Kiekens Department of Pharmaceutical Technology and Biopharmacy, University of Antwerp, Belgium

Poster only

Day 2– Thursday 2nd July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

93. Real-time particle imaging of pharmaceutical tablet disintegration

A. D. Rajkumar1, G. K. Reynolds2, D. Wilson2, M. J. Hounslow1 & A. D. Salman1

1 Department of Chemical and Biological Engineering, University of Sheffield, UK 2 AstraZeneca, UK

Poster Paper

(94)

94. Responsive polymer coated particles for consumer products

L. E. Scullion, P. H Findlay & D. A. Pears

Revolymer (U.K.) Limited, UK Poster only

95. Roll compaction of spray-dried mannitol using different compaction designs and process parameters

K. Csordas & P. Kleinebudde Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-University, Germany

Poster only

96. Roller compactor: the effect of nano-indntation hardness of primary particle

R. B. Al Asady, M. J. Hounslow & A. D. Salman

Department of Chemical and Biological Engineering, University of Sheffield, UK

Poster only

97. Study of the influence of the diameter of a conical hopper orifice on the parameters of the flow equation for size fractions of sorbitol granules

H. Hurychová, M. Azar, Z. Šklubalová & J. Stoniš

Department of Pharmaceutical Technology, Charles University in Prague, Czech Republic

Poster only

98. The development of an NIR interfacing device for the in-line monitoring of a continuous twin-screw granulation process

F. De Leersnyder1, E. Peeters2, C. Vervaet2, J. P. Remon2 & T. De Beer1

1 Laboratory of Pharmaceutical Process Analytical Technology, Belgium 2 Laboratory of Pharmaceutical Technology, Belgium

Poster only

99. The effect of processing route on material surface properties

M. Naderi1, N. Servi1, A. Kondor1, M. Acharya1, J. Dienstmaier1 & D. J. Burnett2

1 Surface Measurement Systems, UK 2 Surface Measurement Systems, USA

Poster only

100. Investigation of nucleation in twin screw granulator using compact powder beds

Q. Ai, R. M. Dhenge, M. J. Hounslow & A. D. Salman

Department of Chemical and Biological Engineering, University of Sheffield, UK

Poster Paper

(95)

101. The specifications for the sustainable-design of thermo-hydro-mechanical processes or

B. Bellocq, A. Duri, B. Cuq & T. Ruiz

Montpellier SupAgro, Université Montpellier, France Poster only

Day 2– Thursday 2nd July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

the elaboration of agglomerated products

102. Twin screw granulation: effect of fill level

S. V. Lute, R. M. Dhenge, M. J. Hounslow & A. D. Salman

Department of Chemical and Biological Engineering, University of Sheffield, UK

Poster Paper

(96)

103. Understanding content non-homogeneity in high shear wet granulation: effects of powder segregation, preferential wetting and solubility

S. Oka1, H. N. Emady1, O. Kašpar2, V. Tokárová2, F. Štěpánek2, R. Ramachandran1 & F. J. Muzzio1

1 Department of Chemical & Biochemical Engineering, The State University of New Jersey, USA 2 Department of Chemical Engineering, Institute of Chemical Technology Prague, Czech Republic

Poster only

104. Understanding pharmaceutical powder blending - iron oxide tracer behaviour and different excipient powders

K. Desai1, K. Hapgood1, D. Barling2, P. Stewart2, D. Morton2

1 Monash Advanced Particle Engineering Lab, Monash University, Australia 2 Monash Institute of Pharmaceutical Science, Monash University, Australia

Poster only

105. Volcanic ash aggregation in the lab – can we mimic natural processes?

S. B. Mueller1, U. Kueppers1, M. Jacob2, P. Ayris1, D. B. Dingwell1, M. Guttzeit2, U. Walter2

1 Department of Earth and Environmental Sciences, Ludwig-Maximilians-Universität München (LMU), Germany 2 Glatt Ingenieurtechnik GmbH, Germany

Poster only

106. Wet granulation in a mini twin screw extruder: effect of process and formulation variables on residence time distribution and granule characteristics

M. Kuhs1, A. B. Albadarin1,2, D. Egan1, S. Rahamatullah1, M. Southern1, D. Croker1 & G. Walker1

1 Chemial & Environmental Sciences, University of Limerick, Ireland 2 School of Chemical Engineering, Queen’s University Belfast, UK

Poster only

107. Roller compaction: effect of relative humidity of lactose powder

C. S. Omar1, R. M. Dhenge1, S. Palzer2, M. J. Hounslow1 & A. D. Salman1

1 Department of Chemical and Biological Engineering, University of Sheffield, UK 2 Nestlé SA Headquarters, Switzerland

Poster Paper

(97)

108. Making individual particle interactions in pressure

C. I. Haider1 , T. Althaus2, G. Niederreiter3, S. Palzer4, M. J. Hounslow1, A. D. Salman1

1 Department of Chemical and Biological Engineering, University of Sheffield, UK 2 Nestlé PTC York, UK

Poster only

Day 2– Thursday 2nd July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

agglomeration of amorphous food powders accessible

3 Nestlé PTC Orbe, Switzerland 4 Nestlé SA Headquarters, Switzerland

109. Roller compactor: powder stickiness

O. Mahmah, M. J. Hounslow & A. D. Salman

Department of Chemical and Biological Engineering, University of Sheffield, UK

Poster only

110. ‘Right-first time’ production of granules’ properties modelling and optimization approaches

W. Alalaween1, M. Mahfouf1 & A. Salman2

1 Department of Automatic Control and Systems Engineering, University of Sheffield, UK 2 Department of Chemical and Biological Engineering, University of Sheffield, UK

Poster only

111. Twin screw granulation: understanding the granulation mechanism of mixing hydrophobic and hydrophilic powders

A. L. Mundozah1, J. J. Cartwright2, C. C. Tridon2, M. J. Hounslow1 & A. D. Salman1

1 Department of Chemical and Biological Engineering, University of Sheffield, UK

2 GSK, UK

Poster only

112. Twin screw wet granulation: binder delivery

M. F. Saleh1, R. M. Dhenge1, J. J. Cartwright2, M. J. Hounslow1 & A. D. Salman1

1 Department of Chemical and Biological Engineering, University of Sheffield, UK

2 GSK, UK

Poster only

113. Twin screw granulation: A step towards granule designing

S. V. Lute, R. M. Dhenge, M. J. Hounslow & A. D. Salman

Department of Chemical and Biological Engineering, University of Sheffield, UK

Poster paper

(98)

114. Granule and tablet properties in a high shear mixer and a fluidized bed granulator

Z. Wang, M. J. Hounslow & A. D. Salman

Department of Chemical and Biological Engineering, University of Sheffield, UK

Poster only

115. Granular flow in high shear mixer A. Al Hassn1, K. Washino2, E. L. Chan2, M. J. Hounslow1 & A. D. Salman1

1 Department of Chemical and Biological Engineering, University

of Sheffield, UK 2 Mechanical Engineering Department, Osaka University, Japan

Poster only

116. Impact of impeller design on high shear wet-granulation

M. Börner, U. Schmidt & M.

Knöll

Hüttlin GmbH, a Bosch Packaging Technology Company, Germany Poster only

Day 2– Thursday 2nd July [PLB-D Floor (D05, D06, D07)]

Last updated: 22/06/2015 01:47:49

117. A novel technique for quantifying the cohesive strength of washcoat

J. Yang1, E. M. Holt2, P. Blanco-

García3, A. Wagland3, M. J.

Hounslow1 & A. D. Salman1

1 Department of Chemical and Biological Engineering, University of

Sheffield, UK 2 Johnson Matthey Technology Centre, Billingham, UK 3 Johnson Matthey Technology Centre, Reading, UK

Poster paper

(99)

118. The effect of twin screw granulation process on the tabletability of microcrystalline cellulose

B. Khorsheed1, G. K.

Reynolds2, M. de Matas2, I.

Gabbott2, R. Ron J2 & A. D.

Salman1

1 Department of Chemical and Biological Engineering, University of

Sheffield, UK 2 AstraZeneca, UK

Poster only

119. Monitoring calcium carbonate precipitation and agglomeration: a comparison of in-line and offline techniques

W. Al Nasser1, K. Pitt2, M. J. Hounslow2 & A. D. Salman2

1 Saudi Aramco Company, Saudi Arabia 2 Department of Chemical and Biological Engineering, University of Sheffield, UK

Poster paper

(100)