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1
Curriculum Vitae
Johns Hopkins University School of Medicine
_________________________________ July 30, 2019
Chetan Bettegowda, MD PhD
DEMOGRAPHIC INFORMATION
Current Appointments
2019-Current Jennison and Novak Families Professor, Departments of Neurosurgery and Oncology
2012-Current Investigator, Ludwig Center for Cancer Genetics and Therapeutics, Johns Hopkins University
2016-Current Director of Meningioma Center, Johns Hopkins Hospital
2018-Current Physician Advisor, Department of Neurosurgery
Personal Data
Johns Hopkins Hospital
Department of Neurosurgery
Phipps Building, Room 118
600 N. Wolfe Street
Baltimore, MD 21287
410-955-8620 (p)
410-955-8534 (f)
Education and Training
Undergraduate
1998 B.S., Biology & Religion (Double Major), Duke University, Durham, NC
Doctoral/Graduate
2005 M.D., Medicine, Johns Hopkins University School of Medicine, Baltimore, MD
2005 Ph.D., Cellular and Molecular Medicine, Johns Hopkins University School of Medicine
Postdoctoral
2005-2006 Intern, General Surgery, Johns Hopkins Hospital, Baltimore, MD
2006-2012 Resident, Neurosurgery, Johns Hopkins Hospital, Baltimore, MD
2009-2011 Research Fellow, Neuro-oncology, Johns Hopkins University School of Medicine
Professional Experience
2006-2012 Resident, Neurosurgery, Johns Hopkins Hospital
2011-2012 Chief Resident, Neurosurgery, Johns Hopkins Hospital
2012-2016 Assistant Professor of Neurosurgery and Oncology, Johns Hopkins University School of Medicine
2016-2019 Associate Professor of Neurosurgery and Oncology, Johns Hopkins University School of Medicine
2018-2019 Jennison-Nowak Families Endowed Associate Professor, Department of Neurosurgery
PUBLICATIONS H-Index: 39 ~11,400 citations
Original Research [OR]
1. Levin ED, Bettegowda C, Weaver T, Christopher NC. Nicotine-dizocilpine interactions and working and
reference memory performance of rats in the radial-arm maze. Pharmacol Biochem Behav. 1998
Nov;61(3):335-40.
2. Levin ED, Bettegowda C, Blosser J, Gordon J. AR-R17779, and alpha7 nicotinic agonist, improves
learning and memory in rats. Behav Pharmacol. 1999 Nov;10(6-7):675-80.
3. Dang LH, Bettegowda C, Huso DL, Kinzler KW, Vogelstein B. Combination bacteriolytic therapy for the
treatment of experimental tumors. PNAS. 2001 Dec 18; 98(26):15155-60.
2
4. Traverso G, Bettegowda C, Kraus J, Speicher MR, Kinzler KW, Vogelstein B, Lengauer C. Hyper-
recombination and genetic instability in BLM-deficient epithelial cells. Cancer Res. 2003 Dec
15;63(24):8578-81.
5. Bettegowda C, Dang LH, Abreams R, Huso DL, Dillehay L, Cheong I, Agrawal N, Borzillary S,
McCaffery JM, Watson EL, Lin KS, Bunz F, Baidoo K, Pomper MG, Kinzler KW, Vogelstein B, Zhou S.
Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria. PNAS. 2003 Dec
9;100(25):15083-8.
6. Dang LH*, Bettegowda C*, Agrawal N, Cheong I, Huso D, Frost P, Loganzo F, Greenberger L, Barkoczy J,
Pettit GR, Smith AB 3rd, Gurulingappa H, Khan S, Parmigiani G, Kinzler KW, Zhou S, Vogelstein B.
Targeting vascular and avascular compartments of tumors with C. novyi-NT and Anti-Microtubule Agents.
Cancer Biol Ther. 2004 Mar;3(3):326-37. (cover article, co-first authors)
7. Agrawal N, Bettegowda C, Cheong I, Geschwind JF, Drake CG, Hipkiss EL, Tatsumi M, Dang LH, Diaz
LA Jr, Pomper M, Abusedera M, Wahl RL, Kinzler KW, Zhou S, Huso DL, Vogelstein B. Bacteriolytic
therapy can generate a potent immune response against experimental tumors. PNAS. 2004 Oct
19;101(42):15172-7.
8. Bettegowda C, Foss CA, Cheong I, Wang Y, Diaz L, Agrawal N, Fox J, Dick J, Dang LH, Zhou S, Kinzler
KW, Vogelstein B, Pomper MG. Imaging bacterial infections with radiolabeled 1-(2’-deoxy-2’-fluro-beta-
D-arabinofuranosyl)-5-iodouracil. PNAS. 2005 Jan 25;102(4):1145-50. 9. Bettegowda C, Foss CA, Cheong I, Wang Y, Diaz L, Agrawal N, Fox J, Dick J, Dang LH, Zhou S, Kinzler
KW, Vogelstein B, Pomper MG. Imaging bacteriolytic therapy with I-125 FIAU. PNAS. 2005 Jan. 25; 102
10. Diaz LA Jr, Cheong I, Foss CA, Zhang X, Peters BA, Agrawal N, Bettegowda C, Karim B, Liu G, Khan K,
Huang X, Kohli M, Dang LH, Hwang P, Vogelstein A, Garrett-Mayer E, Kobrin B, Pomper M, Zhou S,
Kinzler KW, Vogelstein B, Huso DL. Pharmacologic and toxicologic evaluation of C. novyi-NT spores.
Toxicol Sci. 2005 Dec;88(2):562-75.
11. Bettegowda C, Huang X, Lin J, Cheong I, Kohli M, Szabo SA, Zhang X, Diaz LA Jr, Velculescu VE,
Parmigiani G, Kinzler KW, Vogelstein B, Zhou S. The genome and transcriptomes of the anti-tumor agent
Clostridium novyi-NT. Nat Biotechnol. 2006 Dec;24(12):1573-80.
12. Cheong I, Huang X, Bettegowda C, Diaz LA Jr, Kinzler KW, Zhou S, Vogelstein B. A bacterial protein
enhances the release and efficacy of liposomal cancer drugs. Science. 2006 Nov 24;314(5803):1308-11.
13. Plomp M, McCaffery JM, Cheong I, Huang X, Bettegowda C, Kinzler KW, Zhou S, Vogelstein B, Malkin
AJ. Spore coat architecture of Clostridium novyi NT spores. J Bacteriol. 2007 Sep;189(17):6457-68.
14. Diaz LA Jr, Foss CA, Thornton K, Nimmagadda S, Endres CJ, Uzuner O, Seyler TM, Ulrich SD, Conway J,
Bettegowda C, Agrawal N, Cheong I, Zhang X, Ladenson PW, Vogelstein BN, Mont MA, Zhou S, Kinzler
KW, Vogelstein B, Pomper MG. Imaging of Musculoskeletal Bacterial Infections by [I] FIAU-PET/CT.
PLoS ONE. 2007 Oct 10;2(10):e1007.
15. Farrag TY, Agrawal N, Sheth S, Bettegowda C, Ewertz M, Kim M, Tufano RP. Algorithm for safe and
effective reoperative thyroid bed surgery for recurrent/persistent papillary thyroid carcinoma. Head Neck.
2007 Dec;29(12):1069-74.
16. Mehta V, Bettegowda C, Ahmadi SA, Berenberg P, Thomale UW, Haberl EJ, Jallo GI, Ahn E. Spinal Cord
Tethering following Myelomeningocele Repair. J Neurosurg Pediatr. 2010 Nov;6(5):498-505.
17. Mehta V, Bettegowda C, Jallo GI, Ahn E. The Evolution of Surgical Management for Craniosynostosis.
Neurosurg Focus. 2010 Dec;29(6):E5.
18. Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C,
Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, Vandenberg S,
Berger MS, Marie SK, Shinjo SM, Clara C, Phillips PC, Minturn JE, Biegel JA, Judkins AR, Resnick AC,
Storm PB, Curran T, He Y, Rasheed BA, Friedman HS, Keir ST, McLendon R, Northcott PA, Taylor MD,
Burger PC, Riggins GJ, Karchin R, Parmigiani G, Bigner DD, Yan H, Papadopoulos N, Vogelstein B,
Kinzler KW, Velculescu VE. The Genetic Landscape of the Childhood Cancer Medulloblastoma. Science.
2011 Jan 28;331(6016):435-9.
19. Mehta V, Bettegowda C, Amin A, El-Gassim M, Jallo GI, Ahn E. Impact of tethered cord release on
symptoms of Chiari II malformation in children born with a myelomeningocele. Childs Nerv Syst. 2011
Jun;27(6):975-8.
20. Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG,
Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, Bigner DD, Oba-Shinjo SM, Marie SK,
3
Riggins GJ, Kinzler KW, Vogelstein B, Hruban RH, Maitra A, Papadopoulos N, Meeker AK. Altered
Telomeres in Tumors with ATRX and DAXX Mutations Science. 2011 Jul 22;333(6041):425
21. Agrawal N*, Frederick MJ*, Pickering CR*, Bettegowda C*, Chang K, Li RJ, Fakhry C, Xie TX, Zhang J,
Wang J, Zhang N, El-Naggar AK, Jasser SA, Weinstein JN, Treviño L, Drummond JA, Muzny DM, Wu Y,
Wood LD, Hruban RH, Westra WH, Koch WM, Califano JA, Gibbs RA, Sidransky D, Vogelstein B,
Velculescu VE, Papadopoulos N, Wheeler DA, Kinzler KW, Myers JN. Exome Sequencing of Head and
Neck Squamous Cell Carcinomas Reveals Inactivating Mutations in NOTCH1. Science. 2011 Aug
26;333(6046):1154-7 (co-first author)
22. Bettegowda C, Agrawal N, Jiao Y, Sausen M, Wood LD, Hruban RH, Rodriguez FJ, Cahill DP, McLendon
R, Riggins G, Velculescu VE, Oba-Shinjo SM, Marie SK, Vogelstein B, Bigner D, Yan H, Papadopoulos N,
Kinzler KW. Mutations in CIC and FUBP1 Contribute to Human Oligodendroglioma. Science. 2011 Sep
9;333(6048):1453-5.
23. Ononiwu C, Mehta V, Bettegowda C, Jallo G. Pediatric Spinal Glioblastoma Multiforme: Current
Treatment Strategies and Possible Predictors of Survival. Childs Nerv System. 2012 May;28(5):715-20.
24. Wolf A, Batra S, Bortoletto S, Bettegowda C, Amendola B, Blach L, Kleinberg L, Rigamonti D.
Stereotactic radiosurgery of colorectal carcinoma brain metastasis: a multi-institutional experience.
(2012); Cureus. 4(5) e: 46. 25. Wolf A, Stall B, Batra S, Bortoletto S, Bettegowda C, Coy CR, Amendola B, Blach L, Kleinberg L,
Rigamonti D. Gamma knife radiosurgery for melanoma brain metastases. (2012); Cureus. 4(5) e: 4
26. Wolf A, Redmond JK, Bortoletto S, Batra S, Bettegowda C, Amendola B, Blach L, Kleinberg L, Rigamonti
D. Gamma knife radiosurgery for breast cancer metastases to the brain: outcomes and prognostic
factors from a large prospectively collected database. (2012); Cureus. 4(5): e: 43. 27. Wolf A, Batra S, Bortoletto S, Bettegowda C, Amendola B, Blach L, Kleinberg L, Rigamonti D.
Stereotactic radiosurgery for the treatment of brain metastases from non-small cell lung carcinoma: a multi-
institutional experience. (2012); Cureus. 4 (4) e: 41.
28. Jiao Y, Killela PJ, Reitman ZJ, Rasheed AB, Heaphy CM, de Wilde RF, Rodriguez FJ, Rosemberg S, Oba-
Shinjo SM, Marie SK, Bettegowda C, Agrawal N, Lipp E, Pirozzi C, Lopez G, He Y, Friedman H,
Friedman AH, Riggins GJ, Holdhoff M, Burger P, McLendon R, Bigner DD, Vogelstein BK, Meeker AK,
Kinzler KW, Papadopoulos N, Diaz LA, Yan H. Frequent ATRX, CIC and FUBP1 mutations refine the
classification of malignant gliomas. Oncotarget. 2012 Jul:3(7):709-22.
29. Husain H, Savage W, Grossman S, Ye X, Burger P, Everett, Bettegowda C, Diaz L, Blair C, Romans K,
Holdhoff M. Pre-and Post-Operative Plasma Glial Fibrillary Acidic Protein Levels in Patients with Newly
Diagnosed Gliomas. J Neurooncol. 2012 Aug;109(1):123-7.
30. Woodworth GF, See A, Bettegowda C, Batra S, Jallo GI, Rigamonti D. Predictors of Surgery-Free
Outcome in Adult Endoscopic Third Ventriculostomy. World Neurosurg. 2012 Sept-Oct;78(3-4):312-7.
31. Jain A, Amin A, Jain P, Burger P, Jallo GI, Lim M, , Bettegowda C. Subependymoma: Clinical Features
and Surgical Outcomes. Neurol Res. 2012 Sep;34(7):677-84.
32. Agrawal N*, Jiao Y*, Bettegowda C*, Hutfless, Wang Y, David S, Cheng Y, Twaddell W, Latt N, Shin E,
Wang L, Wang LD, Ding I, Yang W, Velculescu V, Vogelstein B, Papadopoulos N, Kinzler K, Meltzer S.
Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma. Cancer
Discov. 2012 Oct;2(10):899-905. (co-first author).
33. Bettegowda C, Adogwa O, Mehta V, Chaichana K, Weingart J, Carson B, Jallo GI, Ahn E. Treatment of
Choroid Plexus Tumors: A Twenty Year Single Institutional Experience. J Neuros Pediatr. 2012
Nov;10(5):398-405.
34. Wolf AL, Batra S, Bortoletto P, Ruzevick, J, Bettegowda C, Coy S, Amendola BE, Blach L, Kleinberg L,
Rigamonti D. Stereotactic Radiosurgery in Treatment of Cerebral Metastases: Histological Differences in
Predictors of Survival. Cureus. 2013 Jan;5(1):e81.
35. Agrawal N, Jiao Y, Sausen M, Leary R, Bettegowda C, Roberts N, Bhan S, Ho A, Khan Z, Bishop J,
Westra W, Wood L, Hruban R, Tufano R, Robinson B, Drale H, Toledo S, Toledo R, Morris L, Ghossein R,
Fagin J, Chan T, Velculescu V, Vogelstein B, Kinzler K, Papadopoulos N, Nelkin B, Ball D. Exomic
sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in
RET and RAS. J Clin Endocr Metab. 2013 Feb;98(2):E364-9. 36. Kinde I*, Bettegowda C*, Wang Y*, Wu J, Agrawal N, Shih IeM, Kurman R, Dao F, Levine DA, Giuntoli
R, Roden R, Eshleman JR, Carvalho JP, Marie SK, Papadopoulos N, Kinzler KW, Vogelstein B, Diaz LA
4
Jr. Evaluation of DNA from the Papanicolaou Test to Detect Ovarian and Endometrial Cancers. Sci Transl
Med. 2013 Jan 9;5(167):167ra4. (co-first author).
37. Bettegowda C, Agrawal N, Jiao Y, Wang Y, Wood L, Rodriguez FJ, Hruban RH, Gallia GL, Binder ZA,
Riggins CJ, Salmasi V, Riggins GJ, Reitman ZJ, Rasheed A, Keir S, Shinjo S, Marie S, McLendon R, Jallo
G, Vogelstein B, Bigner D, Yan H, Kinzler KW, Papadopoulos N. Exomic Sequencing of Four Rare
Central Nervous System Tumor Types. Oncotarget. 2013 Apr;4(4):572-83.
38. Killela PJ*, Reitman ZJ*, Jiao Y*, Bettegowda C*, Agrawal N, Diaz LA, Friedman A, Friedman H, Gallia
GL, Giovanella BV, Grollman AP, He TC, He Y, Hruban RH, Jallo GI, Meeker AK, Mertens F, Netto GJ,
Rasheed BA, Riggins G, Rosenquist TA, Schiffman M, Shih IM, Theodorescu D, Torbenson MS,
Velculescu V, Wang TL, Wentzensen N, Wood LD, Zhang M, McLendon RE, Bigner DD, Papadopoulos N,
Kinzler K, Vogelstein B, Yan H. TERT promoter mutations occur frequently in gliomas and in a subset of
tumors derived from cells with low rates of self-renewal. PNAS. 2013 Apr 9;110(15):6021-6. (co-first
author).
39. Chaichana KL, Flores M, Acharya S, Sampognaro P, Bettegowda C, Rigamonti D, Weingart J, Olivi A,
Gallia GL, Brem H, Lim M, Quinones-Hinojosa A. Survival and Recurrence for Patients Undergoing
Surgery of Skull Base Intracranial Metastases. J Neurol Surg B Skull Base. 2013 Aug;74(4):228-35.
40. Fisher CG, Goldschlager T, Boriani S, Varga PP, Fehlings MG, Bilsky MH, Dekutoski MB, Luzzati A,
Williams RP, Berven S, Chou D, Reynolds JJ, Quraishi NA, Rhines LD, Bettegowda C, Gokaslan ZL. A
novel scientific method for rare and often neglected neoplastic conditions. Evid Based Spine Care J. 2013
Oct;4(2):160-2.
41. Sui IM, Ruzevick J, Zhao Q, Connis N, Jiao Y, Bettegowda C, Xia X, Burger PC, Hann CL, Gallia GL.
Erlotinib inhibits growth of a patient-derived chordoma xenograft. PLoS One. 2013 Nov 15;8(11):378895.
42. Goodwin CR, Yang JX, Bettegowda C, Hwang B, James C, Biser A, Raza S, Bender M, Carson B, Lee JY,
Lim M. Glycerol rhitzotomy via a retrosigmoid approach as an alternative treatment for trigeminal
neuralgia. Clin Neurol Neurosurg. 2013 Dec;115(12):2454-6.
43. Chaichana KL, Gadkaree S, Rao K, Link T, Rigamonti D, Purtell M, Browner I, Weingart J, Olivi A, Gallia
G, Bettegowda C, Brem H, Lim M, Quinones-Hinojosa A. Patients undergoing surgery of intracranial
metastases have different outcomes based on their primary pathology. Neurol Res. 2013 Dec;35(10):1059-
69.
44. Liu G, Bettegowda C, Qiao Y, Staedtke V, Chan KW, Bai R, Li Y, Riggins GJ, Kinzler KW, Bulte JW,
McMahon MT, Gilad AA, Vogelstein B, Zhou S, van Zijl PC. Noninvasive imaging of infection after
treatment with tumor-homing bacteria using chemical exchange saturation transfer (CEST) MRI. Magn
Reson Med. 2013 Dec;70(6):1690-8.
45. Chaichana KL, Rao K, Gadkaree S, Dangelmajer S, Bettegowda C, Rigamonti D, Weingart J, Olivi A,
Gallia GL, Brem H, Lim M, Quinones-Hinojosa A. Factors associated with survival and recurrence for
patients undergoing surgery of cerebellar metastases. Neurol Res. 2014 Jan;36(1):13-25.
46. Bettegowda C*, Sausen M*, Leary RJ*, Kinde I*, Wang Y, Agrawal N, Bartlett BR, Wang H, Luber B,
Alani RM, Antonarakis ES, Azad NS, Bardelli A, Brem H, Cameron JL, Lee CC, Fecher LA, Gallia GL,
Gibbs P, Le D, Giuntoli RL, Goggins M, Hogarty MD, Holdhoff M, Hong SM, Jiao Y, Juhl HH, Kim JJ,
Siravegna G, Laheru DA, Lauricella C, Lim M, Lipson EJ, Marie SK, Netto GJ, Oliner KS, Olivi A, Olsson
L, Riggins GJ, Sartore-Bianchi A, Schmidt K, Shih lM, Oba-Shinjo SM, Siena S, Theodorescu D, Tie J,
Harkins TT, Veronese S, Wang TL, Weingart JD, Wolfgang CL, Wood LD, Xing D, Hruban RH, Wu J,
Allen PJ, Schmidt CM, Choti MA, Velculescu VE, Kinzler KW, Vogelstein B, Papadopoulos N, Diaz LA
Jr. Detection of circulating tumor DNA in early- and late- stage human malignancies. Sci Transl Med. 2014
Feb 19;6(224):224ra24.
47. Chaichana KL, Acharya S, Flores M, Wijesekera O, Rigamonti D, Weingart JD, Olivi A, Bettegowda C,
Gallia GL, Brem H, Lim M, Quinones-Hinojosa A. Identifying better surgical candidates among RPA class
2 patients who underwent surgery for intracranial metastases. World Neurosurg. 2014 Jul-Aug;82(1-
2):e267-75.
48. Tung D, DeCrescenzo G, Welsch D, Cheung PH, Bettegowda C, Saha S. Evaluation of 1-(2-deoxy-2-
fluoro-1-D-arabinofuranosyl)-5-iodouracil (FIAU) as an ex vivo bacterial detection agent. World J
Microbiol Biotechnol. 2014 Aug 2.
49. Roberts NJ, Zhang L, Janku F, Collins A, Bai RY, Staedtke V, Rusk AW, Tung D, Miller M, Roix J,
Khanna KV, Murthy R, Benjamin RS, Helgason T, Szvalb AD, Bird JE, Roy-Chowdhuri S, Zhang HH,
Qiao Y, Karim B, McDaniel J, Elpiner A, Sahora A, Lachowicz J, Phillips B, Turner A, Klein MK, Post G,
5
Diaz LA Jr, Riggins GJ, Papadopoulos N, Kinzler KW, Vogelstein B, Bettegowda C, Huso DL, Varterasian
M, Saha S, Zhou S. Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses.
Sci Transl Med. 2014 Aug 13;6(249):249ra111.
50. Fisher CG, Goldschlager T, Boriani S, Varga PP, Rhines LD, Fehlings MG, Luzzati A, Dekutoski MB,
Reynolds JJ, Chou D, Berven SH, Williams RP, Quraishi NA, Bettegowda C, Gokaslan ZL. An evidence-
based medicine model for rare and often neglected neoplastic conditions. J Neurosurg Spine. 2014 Sep 5.
51. Boriani S, Lo SF, Puvanesarajah V, Fisher CG, Varga PP, Rhines LD, Germscheid NM, Luzzati A, Chou D,
Reynolds JJ, Williams RP, Zadnik P, Groves M, Sciubba DM, Bettegowda C, Gokaslan ZL; AOSpine
Knowledge Forum Tumor. Aneurysmal Bone Cysts of the Spine: Treatment Options and Considerations. J
Neurooncol. 2014 Oct;120(1):171-8.
52. Lange RP, Everett A, Dulloor P, Korley FK, Bettegowda C, Blair C, Grossman SA, Holdhoff M.
Evaluation of Eight Plasma Proteins as Candidate Blood-Based Biomarkers for Malignant Gliomas. Cancer
Invest. 2014 Oct;32(8):423-9.
53. Zhang M, Wang Y, Jones S, Sausen M, McMahon K, Sharma R, Wang Q, Belzberg AJ, Chaichana K,
Gallia GL, Gokaslan ZL, Riggins GJ, Wolinksy JP, Wood LD, Montgomery EA, Hruban RH, Kinzler KW,
Papadopoulos N, Vogelstein B, Bettegowda C. Somatic mutations of SUZ12 in malignant peripheral nerve
sheath tumors. Nat Genet. 2014 Nov;46(11):1170-2.
54. Williams R, Williams R, Sowman B, Boriani S, Varga PP, Luzzati A, Gokaslan ZL, Fehlings MG, Fisher,
CG, Dekutoski MB, Rhines LD, Reynolds J, Bettegowda C, Kawahara N, Quariashi NA. Spinal osteoid
osteoma: a multicentre retrospective cohort study comparison of results with appendicular osteoid osteoma.
Spine J. 2015 Mar;15(3):401-408.
55. Sciubba DM, Macki M, Bydon M, Germscheid NM, Wolinsky JP, Boriani S, Bettegowda C, Chou D,
Luzzati A, Reynolds JJ, Szövérfi Z, Zadnik P, Rhines LD, Gokaslan ZL, Fisher CG, Varga PP. Long-term
outcomes in primary spinal osteochondroma: a multicenter study of 27 patients. J Neurosurg Spine. 2015
Jun;22(6):583-8.
56. Goldstein CL, Varga PP, Gokaslan ZL, Boriani S, Luzzati A, Rhines L, Fisher CG, Chou D, Williams RP,
Dekutoski MB, Quraishi NA, Bettegowda C, Kawahara N, Fehlings MG. Spinal hemangiomas: results of
surgical management for local recurrence and mortality in a multicenter study. Spine. 2015 May 1;40(9)
57. Wang Y, Springer S, Mulvey CL, Silliman N, Schaefer J, Sausen M, James N, Rettig EM, Guo T, Pickering
CR, Bishop JA, Chung CH, Califano JA, Eisele DW, Fakhry C, Gourin CG, Ha PK, Kang H, Kiess A, Koch
WM, Myers JN, Quon H, Richmon JD, Sidransky D, Tufano RP, Westra WH, Bettegowda C, Diaz LA Jr,
Papadopoulos N, Kinzler KW, Vogelstein B, Agrawal N. Detection of somatic mutations and HPV in the
saliva and plasma of patients with head and neck squamous cell carcinomas. Sci Transl Med. 2015 Jun
24;7(293):293ra104
58. Puvanesarajah V, Lo SL, Aygun N, Liauw JA, Jusué-Torres I, Lina IA, Hadelsberg U, Elder BD, Bydon A,
Bettegowda C, Sciubba DM, Wolinsky JP, Rigamonti D, Kleinberg LR, Gokaslan ZL, Witham TF,
Redmond KJ, Lim M. Prognostic factors associated with pain palliation after spine stereotactic body
radiation therapy. J Neurosurg Spine. 2015 Jul 31:1-10.
59. Chaichana KL, Kone L, Bettegowda C, Weingart JD, Olivi A, Lim M, Quinones-Hinojosa A, Gallia GL,
Brem H. Risk of surgical site infection in 401 consecutive patients with glioblastoma with and without
carmustine wafer implantation. Neurol Res 2015 Aug;37(8):717-26.
60. Wang Y, Springer S, Zhang M, McMahon KW, Kinde I, Dobbyn L, Ptak J, Brem H, Chaichana K, Gallia
GL, Gokaslan ZL, Groves ML, Jallo GI, Lim M, Olivi A, Quinones-Hinojosa A, Rigamonti D, Riggins GJ,
Sciubba DM, Weingart JD, Wolinsky JP, Ye X, Oba-Shinjo SM, Marie SK, Holdhoff M, Agrawal N, Diaz
LA Jr, Papadopoulos N, Kinzler KW, Vogelstein B, Bettegowda C. Detection of tumor-derived DNA in
cerebrospinal fluid of patients with primary tumors of the brain and spinal cord. PNAS. 2015 Aug
4;112(31):9704-9
61. Liu A, Sankey EW, Bettegowda C, Burger PC, Jallo GI, Groves ML. Poor prognosis despite aggressive
treatment in adults with intramedullary spinal cord glioblastoma. J Clin Neurosci. 2015 Oct;22(10):1627-31.
62. Li R, Faden DL, Fakhry C, Langelier C, Jiao Y, Wang Y, Wilkerson MD, Pedamallu CS, Old M, Lang J,
Loyo M, Ahn SM, Tan M, Gooi Z, Chan J, Richmon J, Wood LD, Hruban RH, Bishop J, Westra WH,
Chung CH, Califano J, Gourin CG, Bettegowda C, Meyerson M, Papadopoulos N, Kinzler KW, Vogelstein
B, DeRisi JL, Koch WM, Agrawal N. Clinical, Genomic and Metagenomic Characterization of Oral
Tongue Squamous Cell Carcinoma in Patients Who Do Not Smoke. Head Neck. 2015 Nov;37(11):1642-9.
6
63. Eseonu CI, Goodwin CR, Zhou X, Theodros D, Bender MT, Mathios D, Bettegowda C, Lim M. Reduced
CSF leak in complete calvarial reconstructions of microvascular decompression craniectomies using
calcium phosphate cement. J Neurosurg. 2015 Dec;123(6):1476-9.
64. Binder ZA, Wilson KM, Salmasi V, Orr BA, Eberhart CG, Siu IM, Lim M, Weingart JD, Quinones-
Hinojosa A, Bettegowda C, Kassam AB, Olivi A, Brem H, Riggins GJ, Gallia GL. Establishment and
Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere
Cell Lines. PLoS One. 2016 Mar 30;11(3);e0150271.
65. Fehlings MG, Nater A, Zamorano JJ, Tetreault LA, Varga PP, Gokaslan ZL, Boriani S, Fisher CG, Rhines
L, Bettegowda C, Kawahara N, Chou D. Risk Factors for Recurrence of Surgically Treated Conventional
Spinal Schwannomas: Analysis of 169 Patients from a Multicenter International Database. Spine. 2016
Mar;41(5):390-8.
66. Liu A, Jain A, Sankey EW, Jallo GI, Bettegowda C. Sporadic intramedullary hemangioblastoma of the
spine: a single institutional review of 21 cases. Neurol Res. 2016 Mar;38(3):205-9.
67. Fisher CG, Versteeg AL, Dea N, Boriani S, Varga PP, Dekutoski MB, Luzzati A, Gokaslan ZL, Williams
RP, Reynolds JJ, Fehlings MG, Germscheid NM, Bettegowda C, Rhines LD. Surgical management of
spinal chondrosarcomas. Spine 2016 Apr;41(8):678-85
68. Goodwin CR, Woodard CL, Zhou X, Pan J, Olivi A, Xia S, Bettegowda C, Sciubba DM, Pevsner J, Zhu H,
Laterra J. Microarray-Based Phospho-Proteomic Profiling of Complex Biological Systems. Transl
Oncol. 2016 Apr;9(2):124-9
69. Gokaslan ZL, Zadnik PL, Sciubba DM, Germscheid N, Goodwin CR, Wolinsky JP, Bettegowda C, Groves
ML, Luzzati A, Rhines LD, Fisher CG, Varga PP, Dekutoski MB, Clarke MJ, Fehlings MG, Quraishi NA,
Chou D, Reynolds JJ, Williams RP, Kawahara N, Boriani S. Mobile spine chordoma: results of 166 patients
from the AOSpine Knowledge Forum Tumor database. J Neurosurg Spine. 2016 Apr;24(4):644-51.
70. Zhang XM, Zhang HH, McLeroth P, Berkowitz RD, Mont MA, Stabin MG, Siegel BA, Alavi A, Barnett
TM, Gelb J, Petit C, Spaltro J, Cho SY, Pomper MG, Conklin JJ, Bettegowda C, Saha S. [(124)I]FIAU:
Human dosimetry and infection imaging in patients with suspected prosthetic joint infection. Nucl Med Biol.
2016 May;43(5):273-9.
71. Goodwin CR, Liang L, Abu-Bonsrah N, Hdeib A, Elder BD, Kosztowski T, Bettegowda C, Laterra J,
Burger P, Sciubba DM. Extraneural glioblastoma multiforme vertebral metastasis. World Neurosurg. 2017
May;89:578-582.
72. Northcutt BG, Seeburg DP, Shin J, Aygun N, Herzka DA, Theodros D, Goodwin CR, Bettegowda C, Lim
M, Blitz AM. High-Resolution MRI Findings following Trigeminal Rhizotomy. AJNR Am J Neuroradiol.
2016 Jun 30.
73. Wang J, Bender MT, Bettegowda C. Percutaneous Procedures for the Treatment of Trigeminal Neuralgia.
Neurosurg Clin N Am. 2016 Jul;27(3):277-95.
74. Sciubba DM, De la Garza Ramos R, Goodwin CR, Abu-Bonsrah N, Bydon A, Witham TF, Bettegowda C,
Gokaslan ZL, Wolinsky JP. Clinical, surgical, and molecular prognostic factors for survival after spinal
sarcoma resection. Neurosurg Focus. 2016 Aug; 41(2):E9.
75. Plotkin SR, Davis SD, Robertson KA, Akshintala S, Allen J, Fisher MJ, Blakeley JO, Widemann BC,
Ferner RE, Marcus CL; REiNS International Collaboration. Sleep and pulmonary outcomes for clinical
trials of airway plexiform neurofibromas in NF1. Neurology. 2016 Aug 16;87(7 Suppl 1):S13-20.
76. Wolters PL, Martin S, Merker VL, Tonsgard JH, Solomon SE, Baldwin A, Bergner AL, Walsh K, Thmpson
HL, Gardner KL, Hingtgen CM Schorry E, Dudley WN, Franklin B; REiNS International Collaboration.
Patient-reported outcomes of pain and physical functioning in neurofibromatosis clinical trials. Neurology.
2016 Aug 16;87(7 Suppl 1):S4-S12
77. Ahlawat S, Fayad LM, Khan MS, Bredella MA, Harris GJ, Evans DG, Farschtschi S, Jacobs MA, Chhabra
A, Salamon JM, Wenzel R, Mautner VF, Dombi E, Cai W, Plotkin SR, Blakeley JO; Whole Body MRI
Committee for the REiNS International Collaboration. REiNS International Collaboration Members 2016.
Current whole-body MRI applications in the neurofibromatoses: NF1, NF2, and schwannomatosis.
Neurology. 2016 Aug 16;87(7 Suppl 1):S31-9.
78. Hanemann CO, Blakeley JO, Nunes FP, Robertson K, Stemmer-Rachamimov A, Mautner V, Kurtz A,
Ferguson M, Widemann BC, Evans DG, Ferner R, Carroll SL, Korf B, Wolkenstein P, Knight P, Plotkin
SR; REiNS International Collaboration. Current status and recommendations for biomarkers and biobanking
in neurofibromatosis. Neurology. 2016 Aug 16;87(7 Suppl 1):S40-8
7
79. Goodwin CR, Theodros D, Abu-Bonsrah NA, Bender M, Zhou X, De la Garzo-Ramos R, Mathios D,
Garzon-Muvdi T, Blitz AM, Olivi A, Carson B, Bettegowda C. 194 Efficacy of Primary Microvascular
Decompression vs Salvage Microvascular Decompression for Trigeminal Neuroalgia. Neurosurgery. 2016
Aug;63 Suppl 1:176-7.
80. Shen C, Lin DD, Redmond KJ, Link K, Kummerlowe M, Douglass J, Lipson EJ, Sharfman W, Bettegowda
C, Lim M, Kleinberg LR. Imaging and Clinical Profile Following Concurrent Stereotactic Radiation and
Immune Therapy for Melanoma Brain Metastases: Preliminary Results. Int J Radiat Oncol Biol Phys. 2016
Oct 1;96(2S):E134.
81. Charest-Morin R, Boriani S, Fisher CG, Patel SR, Kawahara N, Mendel E, Bettegowda C, Rhines LD.
Benign Tumors of the Spine: Has New Chemotherapy and Interventional Radiology Changed the Treatment
Paradigm? Spine (Phila Pa 1976). 2016 Oct 15;41 Suppl 20:S178-S185.
82. Goodwin CR, Abu-Bonsrah N, Bilsky MH, Reynolds JJ, Rhines LD, Laufer I, Disch AC, Bozsodi A, Patel
SR, Gokaslan ZL, Sciubba DM, Bettegowda C. Clinical Decision Making: Integrating Advances in the
Molecular Understanding of Spine Tumors. Spine (Phila Pa 1976). 2016 Oct 15;41 Suppl 20:S171-S177.
83. Goodwin CR, Abu-Bonsrah N, Rhines LD, Verlaan JJ, Bilsky MH, Laufer I, Boriani S, Sciubba DM,
Bettegowda C. Molecular Markers and Targeted Therapeutics in Metastatic Tumors of the Spine: Changing
the Treatment Paradigms. Spine (Phila Pa 1976). 2016 Oct 15;41 Suppl 20:S218-S223.
84. De la Garza Ramos R, Goodwin CR, Jain A, Abu-Bonsrah N, Fisher CG, Bettegowda C, Sciubba DM.
Development of a Metastatic Spinal Tumor Frailty Index (MSTFI) Using a Nationwide Database and Its
Association with Inpatient Morbidity, Mortality, and Length of Stay After Spine Surgery. World Neurosurg.
2016 Nov; 95:548-555.e4.
85. Batista N, Tee J, Sciubba D, Sahgal A, Laufer I, Weber M, Gokaslan Z, Rhines L, Fehlings M, Patel S, Raja
Rampersaud Y, Reynolds J, Chou D, Bettegowda C, Clarke M, Fisher C. Emerging and established clinical,
histopathological and molecular parametric prognostic factors for metastatic spine disease secondary to lung
cancer: Helping surgeons make decisions. J Clin Neurosci. 2016 Dec;34:15-22.
86. Mathios D, Kim JE, Mangraviti A, Phallen J, Park CK, Jackson CM, Garzon-Muvdi T, Kim E, Theodros D,
Polanczyk M, Martin AM, Suk I, Ye X, Tyler B, Bettegowda C, Brem H, Pardoll DM, Lim M. Anti-PD-1
antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM. Sci Transl
Med. 2016 Dec 21;8(370):370ra180.
87. Wang J, Bettegowda C. Applications of DNA-Based Liquid Biopsy for Central Nervous System
Neoplasms. Mol Diagn. 2017 Jan;19(1):24-34.
88. Bettegowda C, Yip S, Lo SL, Fisher CG, Boriani S, Rhines LD, Wang JY, Lazary A, Gambarotti M, Wang
WL, Luzzati A, Dekutoski MB, Bilsky MH, Chou D, Fehlings MG, McCarthy EF, Quraishi NA, Reynolds
JJ, Sciubba DM, Williams RP, Wolinsky JP, Zadnik PL, Zhang M, Germscheid NM, Kalampoki V, Varga
PP, Gokaslan ZL; AOSpine Knowledge Forum Tumor. Spinal column chordoma: prognostic significance of
clinical variables and T (brachyury) gene SNP rs2305089 for local recurrence and overall survival. Neuro
Oncol. 2017 Mar 1;19(3):405-413.
89. Quraishi NA, Boriani S, Sabou S, Varga PP, Luzzati A, Gokaslan ZL, G Fehlings M, Fisher CG, Dekutoski
MB, Rhines LD, Reynolds JJ, Germscheid NM, Bettegowda C, Williams RP. A multicentre cohort study of
spinal osteoid osteomas: results of surgical treatment and analysis of local recurrence. Spine J. 2017
Mar;17(3):401-408.
90. Daniels M, Garzon-Muvdi T, Maxwell R, Tamargo RJ, Huang J, Witham T, Bettegowda C, Chaichana KL.
Pre-Residency Publication Number Does Not Predict Academic Career Placement in Neurosurgery. World
Neurosurg. 2017 May;101:350-356.
91. Theodros D, Goodwin RC, Bender MT, Zhou X, Garzon-Muvdi T, De la Garza-Ramos R, Abu-Bonsrah N,
Mathios D, Blitz AM, Olivi A, Carson B, Bettegowda C, Lim M. Efficacy or primary microvascular
decompression versus subsequent microvascular decompression for trigeminal neuroalgia. J Neurosurg.
2017 May;126(5):1691-1697.
92. Abu-Bonsrah N, Goodwin CR, De la Garza-Ramos R, Sankey EW, Liu A, Kosztowski T, Elder
BD, Bettegowda C, Bydon A, Witham TF, Wolinsky JP, Gokaslan ZL, Sciubba DM. Readmissions After
Surgical Resection of Metastatic Tumors of the Spine at a Single Institution. World Neurosurg. 2017
May;101:695-701.
93. Holdhoff M, Cairncross GJ, Kollmeyer TM, Zhang M, Zhang P, Mehta MP, Werner-Wasik M, Souhami L,
Bahary JP, Kwok Y, Hartford AC, Chakravarti A, Yegnasubramanian S, Vogelstein B, Papadopoulos N,
8
Kinzler K, Jenkins RB, Bettegowda C. Genetic landscape of extreme responders with anaplastic
oligodendroglioma. Oncotarget. 2017 May 30;8(22):35523-35531.
94. Maxwell R, Garzon-Muvdi T, Lipson EJ, Sharfman WH, Bettegowda C, Redmond KJ, Kleinberg LR, Ye
X, Lim M. BRAF-V600 mutational status affects recurrence patterns of melanoma brain metastasis. Int J
Cancer. 2017 Jun 15;140(12):2716-2727.
95. Chen L, Shen C, Redmond KJ, Page BR, Kummerlowe M, Mcnutt T, Bettegowda C, Rigamonti D, Lim M,
Kleinberg L. Use of Stereotactic Radiosurgery in Elderly and Very Elderly Patients With Brain Metastases
to Limit Toxicity Associated With Whole Brain Radiation Therapy. Int J Radiat Oncol Biol Phys. 2017 Jul
15; 98(4):939-947.
96. Hua J, Miao X, Agarwal S, Bettegowda C, Quiñones-Hinojosa A, Laterra J, Van Zijl PCM, Pekar JJ, Pillai
JJ. Language Mapping Using T2-Prepared BOLD Functional MRI in the Presence of Large Susceptibility
Artifacts-Initial Results in Patients With Brain Tumor and Epilepsy. Tomography. 2017 Jun;3(2):105-113.
97. Charest-Morin R, Dirks MS, Patel S, Boriani S, Luzzati A, Fehlings MG, Fisher CG, Dekutoski MB,
Williams R, Quraishi NA, Gokaslan ZL, Bettegowda C, Germscheid NM, Varga PP, Rhines LD; AOSpine
Knowledge Forum Tumor. Ewing's Sarcoma of the Spine: Prognostic Variables for Survival and Local
Control in Surgically Treated Patients. Spine. 2017 Aug 23.
98. Wu A, Weingart JD, Gallia GL, Lim M, Brem H, Bettegowda C, Chaichana KL. Risk Factors for
Preoperative Seizures and Loss of Seizure Control in Patients Undergoing Surgery for Metastatic Brain
Tumors. World Neurosurg. 2017 Aug;104:120-128.
99. Figueroa JM, Skog J, Akers J, Li H, Komotar R, Jensen R, Ringel F, Yang I, Kalkanis S, Thompson R,
LoGuidice L, Berghoff E, Parsa A, Liau L, Curry W, Cahill D, Bettegowda C, Lang FF, Chiocca EA,
Henson J, Kim R, Breakefield X, Chen C, Messer K, Hochberg F, Carter BS. Detection of wtEGFR
Amplification and EGFRvIII Mutation in CSF-Derived Extracellular Vesicles of Glioblastoma Patients.
Neuro Oncol. 2017 Oct 19;19(11):1494-1502.
100. Ehresman JS, Garzon-Muvdi T, Rogers D, Lim M, Gallia GL, Weingart J, Brem H, Bettegowda C,
Chaichana KL. The Relevance of Simpson Grade Resections in Modern Neurosurgical Treatment of World
Health Organization Grade I, II, and III Meningiomas. World Neurosurg. 2018 Jan;109:e588-e593.
101. Cohen JD, Li L, Wang Y, Thoburn C, Afsari B, Danilova L, Douville C, Javed AA, Wong F, Mattox A,
Hruban RH, Wolfgang CL, Goggins MG, Dal Molin M, Wang TL, Roden R, Klein AP, Ptak J, Dobbyn L,
Schaefer J, Silliman N, Popoli M, Vogelstein JT, Browne JD, Schoen RE, Brand RE, Tie J, Gibbs P, Wong
HL, Mansfield AS, Jen J, Hanash SM, Falconi M, Allen PJ, Zhou S, Bettegowda C, Diaz L, Tomasetti C,
Kinzler KW, Vogelstein B, Lennon AM, Papadopoulos N. Detection and localization of surgically
resectable cancers with a multi-analyte blood test. Science. 2018 Feb 23;359(6378):926-930
102. Chaichana KL, Vivas-Buitrago T, Jackson C, Ehresman J, Olivi A, Bettegowda C, Quinones-Hinojosa A.
The Radiographic Effects of Surgical Approach and Use of Retractors On the Brain after Anterior Cranial
Fossa Meningioma Resection. World Neurosurg. 2018 Jan 20. pii: S1878-8750(18)30112-8.
103. Versteeg AL, Sahgal A, Rhines LD, Sciubba DM, Schuster JM, Weber MH, Varga PP, Boriani S,
Bettegowda C, Fehlings MG, Clarke MJ, Arnold PM, Gokaslan ZL, Fisher CG; AOSpine Knowledge
Forum Tumor. Psychometric evaluation and adaptation of the Spine Oncology Study Group Outcomes
Questionnaire to evaluate health-related quality of life in patients with spinal metastases. Cancer. 2018 Feb
6.
104. Chen L, Douglass J, Kleinberg L, Ye X, Marciscano AE, Forde PM, Brahmer J, Lipson E, Sharfman W,
Hammers H, Naidoo J, Bettegowda C, Lim M, Redmond KJ. Concurrent Immune Checkpoint Inhibitors
and Stereotactic Radiosurgery for Brain Metastases in Non-Small Cell Lung Cancer, Melanoma, and Renal
Cell Carcinoma. Int J Radiat Oncol Biol Phys. 2018 Mar 15;100(4):916-925.
105. Wu A, Doshi T, Hung A, Garzon-Muvdi T, Bender MT, Bettegowda C, Lim M. Immediate and Long-term
Outcomes of Microvascular Decompression for Mixed Trigeminal Neuralgia. World Neurosurg. 2018 Jun
12.
106. Palsgrove DN, Brosnan-Cashman JA, Giannini C, Raghunathan A, Jentoft M, Bettegowda C, Gokden M,
Lin D, Yuan M, Lin MT, Heaphy CM, Rodriguez FJ. Subependymal giant cell astrocytoma-like
astrocytoma: a neoplasm with a distinct phenotype and frequent neurofibromatosis type-1-association. Mod
Pathol. 2018 Jul 4.
107. Gui C, Moore J, Grimm J, Kleinberg L, McNutt T, Shen C, Chen L, Bettegowda C, Lim M, Redmond KJ.
Local recurrence patterns after postoperative stereotactic radiation surgery to resected brain metastases: A
quantitative analysis to guide target delineation. Pract Radiat Oncol. 2018 Apr 26.
9
108. Agarwal S, Hua J, Sair HI, Gujar S, Bettegowda C, Lu H, Pillai JJ. Repeatability of language fMRI
lateralization and localization metrics in brain tumor patients. Hum Brain Mapp. 2018 Aug 4.
109. Xia Y, Mashouf LA, Maxwell R, Peng LC, Lipson EJ, Sharfman WH, Bettegowda C, Redmond KJ,
Kleinberg LR, Lim M. Adjuvant radiotherapy and outcomes of presumed hemorrhagic melanoma brain
metastases without malignant cells. Surg Neurol Int. 2018 Jul 26;9:146.
110. Maxwell R, Luksik AS, Garzon-Muvdi T, Yang W, Huang J, Bettegowda C, Jallo GI, Terezakis SA,
Groves M. Population-based Study Determining Predictors of Cancer-Specific Mortality and Survival in
Pediatric High-grade Brainstem Glioma. World Neurosurg. 2018 Aug 20
111. Goodwin CR, Ahmed AK, Boone C, Abu-Bonsrah N, Xu R, Germscheid N, Fourney DR, Clarke M, Laufer
I, Fisher CG, Bettegowda C, Sciubba DM. The Challenges of Renal Cell Carcinoma Metastatic to the
Spine: A Systematic Review of Survival and Treatment. Global Spine J. 2018 Aug;8(5):517-52.
112. Xia Y, Mashouf LA, Baker BR, Maxwell R, Bettegowda C, Redmond KJ, Kleinberg LR, Lim M.
Outcomes of Metastatic Brain Lesions Treated with Radioactive Cs-131 Seeds after Surgery: Experience
from One Institution. Cureus. 2018 Jul 30;10(7):e3075
113. Barzilai O, Versteeg AL, Sahgal A, Rhines LD, Bilsky MH, Sciubba DM, Schuster JM, Weber MH, Pal
Varga P, Boriani S, Bettegowda C, Fehlings MG, Yamada Y, Clarke MJ, Arnold PM, Gokaslan ZL, Fisher
CG, Laufer I. Survival, local control, and health-related quality of life in patients with oligometastatic and
polymetastatic spinal tumors: A multicenter, international study. Cancer. 2018 Nov 29.
114. Gallia GL, Zhang M, Ning Y, Haffner MC, Batista D, Binder ZA, Bishop JA, Hann CL, Hruban RH, Ishii
M, Klein AP, Reh DD, Rooper LM, Salmasi V, Tamargo RJ, Wang Q, Williamson T, Zhao T, Zou Y,
Meeker AK, Agrawal N, Vogelstein B, Kinzler KW, Papadopoulos N, Bettegowda C. Genomic analysis
identifies frequent deletions of Dystrophin in olfactory neuroblastoma. Nat Commun. 2018 Dec
21;9(1):5410
115. Ehresman JS, Garzon-Muvdi T, Rogers D, Lim M, Gallia GL, Weingart J, Brem H, Bettegowda C,
Chaichana KL. Risk of Developing Postoperative Deficits Based on Tumor Location after Surgical
Resection of an Intracranial Meningioma. J Neurol Surg B Skull Base. 2019 Feb;80(1):59-6
116. Kim TY, Jackson CM, Xia Y, Mashouf LA, Patel KK, Kim ES, Hung AL, Wu A, Garzon-Muvdi T, Bender
MT, Bettegowda C, Lee JYK, Lim M. Retrosigmoid approach for glycerin rhizotomy in the treatment of
trigeminal neuralgia without overt arterial compression: updated case series. J Neurosurg. 2019 Mar 8:1-
117. Schreck KC, Ranjan S, Skorupan N, Bettegowda C, Eberhart CG, Ames HM, Holdhoff M. Incidence and
clinicopathologic features of H3 K27M mutations in adults with radiographically-determined midline
gliomas. J Neurooncol. 2019 May;143(1):87-93
118. Bettegowda C, Yip S, Jiang B, Wang WL, Clarke MJ, Lazary A, Gambarotti M, Zhang M, Sciubba DM,
Wolinsky JP, Goodwin CR, McCarthy E, Germscheid NM, Sahgal A, Gokaslan ZL, Boriani S, Varga PP,
Fisher CG, Rhines LD. Prognostic significance of hTERT (human telomerase reverse transcriptase)
promoter region mutations C228T and C250T for overall survival in spinal chordomas. Neuro Oncol. 2019
Apr 12
119. Kerekes D, Goodwin CR, Ahmed AK, Verlaan JJ, Bettegowda C, Abu-Bonsrah N, Sciubba DM. Local and
Distant Recurrence in Resected Sacral Chordomas: A Systematic Review and Pooled Cohort Analysis.
Global Spine J. 2019 Apr;9(2):191-201
120. Xie E, Garzon-Muvdi T, Bender M, Doshi T, Carson B, Lim M, Bettegowda C. Association Between
Radiofrequency Rhizotomy Parameters and Duration of Pain Relief in Trigeminal Neuralgia Patients with
Recurrent Pain. World Neurosurg. 2019 May 15.
121. Charest-Morin R, Fisher CG, Sahgal A, Boriani S, Gokaslan ZL, Lazary A, Reynolds J, Bettegowda C,
Rhines LD, Dea N. Primary Bone Tumor of the Spine-An Evolving Field: What a General Spine
Surgeon Should Know. Global Spine J. 2019 May;9
122. Barzilai O, Boriani S, Fisher CG, Sahgal A, Verlaan JJ, Gokaslan ZL, Lazary A, Bettegowda C, Rhines
LD, Laufer I. Essential Concepts for the Management of Metastatic Spine Disease: What the
Surgeon Should Know and Practice. Global Spine J. 2019 May;9
123. Al-Khindi T, Shen CJ, Peng L, Redmond KJ, Lim M, Kleinberg LR, Bettegowda C. Assessing the
Effectiveness of Systemic Therapy after Stereotactic Radiosurgery on Cancer Recurrence and All-Cause
Mortality. World Neurosurg. 2019 May 31
124. Hwang T, Mathios D, McDonald KL, Daris I, Park SH, Burger PC, Kim S, Dho YS, Carolyn
H, Bettegowda C, Shin JH, Lim M, Park CK. Integrative analysis of DNA methylation suggests down-
10
regulation of oncogenic pathways and reduced somatic mutation rates in survival outliers of glioblastoma.
Acta Neuropathol Commun. 2019 Jun 3;7(1):5
124. Xia Y, Kim TY, Mashouf LA, Patel KK, Xu R, Casaos J, Choi J, Kim ES, Hung AL, Wu A, Garzon-Muvdi
T, Bender MT, Jackson CM, Bettegowda C, Lim M. Absence of Ischemic Injury after Sacrificing the
Superior Petrosal Vein during Microvascular Decompression. Oper Neurosurg. 2019 Jun 19
125. Charest-Morin R, Fisher CG, Versteeg AL, Sahgal A, Varga PP, Sciubba DM, Schuster JM, Weber MH,
Clarke MJ, Rhines LD, Boriani S, Bettegowda C, Fehlings MG, Arnold PM, Gokaslan ZL, Dea N. Clinical
presentation, management and outcomes of sacral metastases: a multicenter, retrospective cohort study. Ann
Transl Med. 2019 May;7(10):214
126. Azad TD, Jiang B, Bettegowda C. Molecular foundations of primary spinal tumors-implications for
surgical management. Ann Transl Med. 2019 May;7(10):222
127. Hanel RA, Kallmes DF, Lopes DK, Nelson PK, Siddiqui A, Jabbour P, Pereira VM, Szikora István I, Zaidat
OO, Bettegowda C, Colby GP, Mokin M, Schirmer C, Hellinger FR, Given Ii C, Krings T, Taussky P, Toth
G, Fraser JF, Chen M, Priest R, Kan P, Fiorella D, Frei D, Aagaard-Kienitz B, Diaz O, Malek AM, Cawley
CM, Puri AS. Prospective study on embolization of intracranial aneurysms with the pipeline device: the
PREMIER study 1 year results. J Neurointerv Surg. 2019 Jul 15
Systematic Reviews [SR]
1. Sciubba DM, Goodwin CR, Yurter A, Ju D, Gokaslan ZL, Fisher C, Rhines LD, Fehlings MG, Fourney DR,
Mendel E, Laufer I, Bettegowda C, Patel SR, Rampersaud YR, Sahgal A, Reynolds J, Chou D, Weber MH,
Clarke MJ. A Systematic Review of Clinical Outcomes and Prognostic Factors for Patients Undergoing
Surgery for Spinal Metastases Secondary to Breast Cancer. Global Spine J. 2016 Aug;6(5):482-96
2. Ailon T, Torabi R, Fisher CG, Rhines LD, Clarke MJ, Bettegowda C, Boriani S, Yamada YJ, Kawahara N,
Varga PP, Shin JH, Saghal A, Gokaslan ZL. Management of Locally Recurrent Chordoma of the Mobile
Spine and Sacrum: A Systematic Review. Spine (Phila Pa 1976). 2016 Oct 15;41 Suppl 20:S193-S198.
3. Clarke MJ, Molina CA, Fourney DR, Fisher CG, Gokaslan ZL, Schmidt MH, Rhines LD, Fehlings MG,
Laufer I, Patel SR, Rampersaud YR, Reynolds J, Chou D, Bettegowda C, Mendel E, Weber MH, Sciubba
DM. Systematic Review of the Outcomes of Surgical Treatment of Prostate Metastases to the Spine. Global
Spine J. 2017 Aug;7(5):460-468.
Review Articles [RA]
1. Zhou S, Bettegowda C, Agrawal N. Combination bacteriolytic cancer therapy: Attacking cancer from
inside out. Discov Med. 2004 Feb;4(20):33-7
2. Hsu W, Bettegowda C, Jallo GI. Intramedullary Spinal Cord Tumor Surgery: Can we do it without
neurophysiological monitoring? Childs Nerv Syst. 2010 Feb;26(2):241-5.
3. Bettegowda C. Staying Alive: Specifically Targeting Tumor Vessels with Anti-Angiogenesis Therapy. Sci
Translat Med 2012 Mar 6.
4. Bettegowda C. Tumors and Microbes Sitting in a Tree. Sci Translat Med. 2012 Apr 3.
5. Bettegowda C, Brain Tumor Diagnostics Go Micro. Sci Translat Med. 2012 May 1.
6. Bettegowda C, Papadopoulos N, Agrawal N. Mapping Genes for Oligodendroglioma. J Personalized Med.
2012 May 9.
7. Bettegowda C, Pesticides Perturb Prenatal Brain. Sci Translat Med. 2012 May 29.
8. Bettegowda C, Circulating Tumor Cells Bad News in Breast Cancer Sci Translat Med. 2012 July 25
9. Bettegowda C, A Window of Opportunity for Alzheimer’s Disease. Sci Translat Med. 2012 Aug 21.
10. Bettegowda C, Fruit Flies Create a Buzz About Hearing. Sci Translat Med. 2012 Sept 18.
11. Bettegowda C. Ironing out MYC in Prostate Cancer. Sci Translat Med. 2012 Oct 17. 12. Bettegowda C. Reactivating the natural killer. Sci Translat Med. 2012 Nov 13. 13. Bettegowda, C. Remembering the variants in Alzheimer’s Disease. Sci Translat Med. 2012 Dec 11. 14. Bettegowda C, Fragmenting malignant melanoma Sci Translat Med. 2013 Jan 15. 15. Bettegowda C. Running interference on tumor growth. Sci Translat Med. 2013 Feb 12. 16. Loyo M, Li R, Bettegowda C, Pickering C, Frederick M, Myers F, Agrawal N. Lessons learned from Next
Generation Sequencing in Head and Neck Cancer. Head Neck. 2013 Mar;35(3):454-63. 17. Zadnik P, Burger P, Gokaslan Z, Bettegowda C. Spinal cord tumors: genetic advances and implications for
treatment. Nat Rev Neurol. 2013 May;9(5):257-66.
11
18. Zadnik PL, Gokaslan ZL, Burger PC, Bettegowda C. Spinal cord tumours: advances in genetics and their
implications for treatment. Nat Rev Neurol. 2013 May;9(5):257-66. 19. Ambady P, Bettegowda C, Holdhoff M. Emerging methods for disease monitoring in malignant gliomas.
CNS Oncol. 2013 Nov 2(6); 511-522
20. Wang J and Bettegowda C. Genomic discoveries in adult astrocytoma. Curr Opin Genet Dev. 2015
Feb;30:17-24.
21. Wang J and Bettegowda C. Genetics and immunotherapy: using the genetic landscape of gliomas to inform
management strategies. J Neurooncol. 2015 Jul;123(3):373-83.
22. Theodros D, Patel M, Ruzevick J, Lim M, Bettegowda C. Pituitary adenomas: historical perspective,
surgical management end future directions. CNS Oncol. 2015;4(6):411-29.
23. Baron R, Ferriero DM, Frisoni GB, Bettegowda C, Gokaslan ZL, Kessler JA, Vezzani A, Waxman SG,
Jarius S, Wildemann B, Weller M. Neurology-the next 10 years. Nat Rev Neurol. 2015 Nov;11(11):658-64.
24. Lim M, Xia Y, Bettegowda C, Weller M. Current state of immunotherapy for glioblastoma. Nat Rev Clin
Oncol. 2018 Apr 11
25. Labak CM, Holdhoff M, Bettegowda C, Gallia GL, Lim M, Weingart JD, Mukherjee D. Surgical Resection
for Primary Central Nervous System Lymphoma: A Systematic Review. World Neurosurg. 2019 Mar 20
Book Chapters, Monographs [BC]
1. Bettegowda C, Huang J. Burr Holes. In Fundamentals of Operative Neurosurgery (Connolly E,
McKhann G, Huang J, Choudhri T, eds.) Thieme. New York, NY. 2009.
2. Bettegowda C, Huang J. Epidural Hematoma Evacuation. In Fundamentals of Operative Neurosurgery
(Connolly E, McKhann G, Huang J, Choudhri T, eds). Thieme. New York, NY. 2009.
3. Bettegowda C, Huang J. Subdural Hematoma Evacuation. In Fundamentals of Operative Neurosurgery
(Connolly E, McKhann G, Huang J, Choudhri T, eds). Thieme. New York, NY. 2009.
4. Bettegowda C, Huang J. Infected Bone Flap and Subdural or Epidural Abscess/Empyema. In
Fundamentals of Operative Neurosurgery (Connolly E, McKhann G, Huang J, Choudhri T, eds). Thieme.
New York, NY. 2009.
5. Bettegowda C, Jallo G. Suboccipital and Teleovelar Approaches. In Contemporary Skull Base Surgery
(Quinones A, Conway J, Jallo G eds). Plural. San Diego, CA. 2009.
6. Bettegowda C, Amin A, Hoang S, Jallo G. Supratentorial Tumors. In Handbook of Neurosurgery
(Rigamonti ed). Thieme. New York, NY. 2009.
7. Bettegowda C, Batra S, Chan J, Rigamonti D. Cerebral Metastases. In Handbook of Neurosurgery
(Rigamonti ed). Thieme. New York, NY. 2009.
8. Hoang S, Bettegowda C, Jallo G. Craniopharyngiomas and Suprasellar Tumors. In Handbook of
Neurosurgery (Rigamonti ed). Thieme. New York, NY. 2009.
9. Hoang S, Bettegowda C, Jallo G. Pediatric Posterior Fossa Tumors. In Handbook of Neurosurgery
(Rigamonti ed). Thieme. New York, NY. 2009.
10. Bettegowda C, Raza S, Jallo G, Quinones A. Supraorbital Craniotomy. In Essential Technique in
Operative Neurosurgery. (Jandial R, McCormick P, Black P eds). Elsevier. New York, NY. 2009.
11. Bettegowda C, Mehta V, Kretzer R, Jallo G. Intramedullary Spinal Cord Cavernous Malformation. In
Essential Technique in Operative Neurosurgery. (Jandial R, McCormick P, Black P eds). Elsevier. New
York, NY. 2009.
12. Kretzer R, Bettegowda C, Jallo G. Intradural Tumor – Meningioma. In Essential Technique in Operative
Neurosurgery. (Jandial R, McCormick P, Black P eds). Elsevier. New York, NY. 2009.
13. Bettegowda C, Kretzer R, Belzberg A, Jallo G. Intradural Nerve Sheath Tumors. In Essential Technique
in Operative Neurosurgery. (Jandial R, McCormick P, Black P eds). Elsevier. New York, NY. 2009.
14. Kretzer R, Bettegowda C, Jallo G. Intramedullary Spinal Cord Tumors. In Essential Technique in
Operative Neurosurgery. (Jandial R, McCormick P, Black P eds). Elsevier. New York, NY. 2009.
15. Bettegowda C, Chen L, Mehta V, Jallo GI, Rutka J. Supratentorial Tumors in the Pediatric Population:
Multidisciplinary Management. Schmidek and Sweet’s Operative Neurosurgical Techniques, Sixth
Edition. Elsevier. New York, NY. 2010.
16. Bettegowda C, Byun Y, Foss C, Nimmagadda S, Sgourous G, Ambinder R, Pomper M. Imaging
Infection Based on Expression of Thymidine Kinase. Target Molecular Imaging. (Welch and Eckelman
eds). First Edition. Taylor & Francis. New York, NY. 2012.
12
17. Papadimitriou K, Bettegowda C, Vrionis F. Molecular Genetics of Brain Tumors. Gliomas:
Symptoms,Diagnosis and Treatment Options. (Wiranowska and Vrionis eds). Nova Science.
Hauppauge, NY 2012. 18. Wang J, Bettegowda C, Jallo GI. The Genetic Landscape of the Childhood Cancer Medulloblastoma.
(Bednok et al eds). Congress of Neurological Surgeons, Schaumburg IL 2014.
19. Ehresman J and Bettegowda C. Genetic factors associated with outcomes in malignant brain tumors.
Comprehensive Overview of Modern Surgical Approaches to Intrinsic Neoplasms. Elsevier 2017.
Case Reports [CR]
1. Mehta V, Bettegowda C, Jallo GI. Intramedullary Tumoral Calcinosis, A Case Report. J Neurosurg-
Pediatr. 2010 Jun;5(6):630-5.
2. Mehta V, Bettegowda C, Singer HS, Ahn E. Medullary Cistern Choroid Plexus Papilloma. Childs Nerv
Syst. 2010 Dec;26(12):1825-9.
3. Bydon M, De la Garza-Ramos R, Bettegowda C, Suk I, Wolinsky JP, Gokaslan ZL. En Bloc Resection of a
Giant Cell Tumor in the Sacrum via a Posterior-Only Approach Without Nerve Root Sacrifice: Technical
Case Report. Neurosurgery. 2015 Sep;11 Suppl 3:E472-8.
4. Bettegowda C, Shajari M, Suk I, Simmons O, Gokaslan ZL, Wolinsky JP. Sublabial Approach for the
Treatment of Symptomatic Basilar Impression in a Patient with Klippel-Feil Syndrome: A Case Report.
Neurosurgery (cover article). 2011 Sep;69(1 Suppl Operative):ons77-82; discussion ons82.
Proceedings, Reports [PR]
1. Huse JT, Wallace M, Aldape KD, Berger MS, Bettegowda C, Brat DJ, Cahill DP, Cloughesy T, Haas-
Kogan DA, Marra M, Miller CR, Nelson SJ, Salama SR, Soffietti R, Wen PY, Yip S, Yen K, Costello JF,
Chang S. Where are we now? And where are we going? A report from the Accelerate Brain Cancer Cure
(ABC2) Low-grade glioma research workshop. Neuro Oncol. 2014 Jan;16(2):173-8.
FUNDING
Extramural Sponsorship
Current
7/1/19-6/30/21 MRgFUS-enabled non-invasive interrogation of malignant glioma via circulating tumor
DNA
NINDS R21NS113016-01
Role: co-PI (co-PI Woodworth), 10%; Major Goals: The goal is test whether MR guided
focused ultrasound can increase the release of circulating tumor DNA in malignant gliomas.
9/1/18-8/31/23 Earlier Detection of Cancers using Non-Plasma Based Liquid Biopsies
NCI U01CA230691-01
Role: Project Co-PI, 15%; Major Goals: Develop novel non-invasive biomarkers for early
detection of cancers.
7/1/18-6/30/23 Tumor Derived DNA in Cerebrospinal Fluid as a Biomarker for Central Nervous System
Malignancies
NCI R37 CA230400-01
Role: PI; Major Goals: Use tumor derived DNA in the CSF as a biomarker to track disease
status in individuals with primary brain tumors.
7/1/18-3/31/20 Optimized Multi-Analyte Blood Test for the Early Detection of Cancer
Commonwealth Foundation
Role: Co-PI; Major Goals: Use combination of protein and DNA biomarkers for the
detection of incipient tumors throughout the body.
9/1/12-8/31/20 Translational molecular profiling of oligodendrogliomas.
Burroughs Wellcome Fund Career Award for Medical Scientists
13
Role: PI, 8% Major Goals: Study the global genetic and epigenetic profiles of
oligodendrogliomas to understand the key pathways that are dysregulated and attempt to
harness this information for diagnostic, prognostic and therapeutic benefit.
7/15/13-12/31/19 Biomarkers for Children With Brain Tumors
Ian’s Friend’s Foundation
Role: Co-PI, 0%; Major Goals: Develop CSF based biomarkers for children with brain
tumors
1/1/16-12/31/20 Development of personalized biomarkers for children with medulloblastoma.
Alex’s Lemonade Stand
Role: PI, 0%; Major Goals: Develop biomarkers capable of detecting disease burden in
individuals with medulloblastoma.
3/1/16-8/31/19 Exploiting frequent alterations in PRC2 in MPNSTs for translational benefit
Department of Defense
Role: PI, 15%; Major Goals: Exploit mutations in the PRC2 complex for diagnostic
purposes in individuals with MPNST
4/1/16-3/31/20 PTRON – Primary Tumor Research and Outcome Network
AOSpine
Role: PI, 1%; Major Goals: Multinational registry of primary spinal column tumors
undergoing surgical treatment
4/27/16-9/30/20 A Phase 2/3 Randomized, Open-Label Study of Toca 511, a Retroviral Replicating Vector,
Combined With Toca FC versus Standard of Care in Subjects Undergoing Planned
Resection for Recurrent Glioblastoma or Anaplastic Astrocytoma
Role: PI, 1.5%; Major Goals: Clinical trial testing efficacy of viral vector for treatment of
recurrent high grade glioma.
9/1/16-8/31/19 Provocative Question 6: Exploiting Frequent Alterations in the PRC2 Complex to
Distinguish Benign Neurofibromas from Malignant Peripheral Nerve Sheath Tumors
National Cancer Institute R21
Role: PI, 20%; Major Goals: Understand the molecular progression from benign
neurofibroma to malignant peripheral nerve sheath tumor.
1/1/17-7/31/19 A Novel Mutation-Based Blood Test for the Earlier Detection of Cancers
Marcus Foundation
Role: Co-Investigator, 2% (PI: Vogelstein); Major Goals: 1. Detection of incipient cancers
in asymptomatic individuals. 2. Detection of occult disease in patients already diagnosed
with cancer.
Past
4/1/15-3/31/19 PREMIER Study: PRospective Study on EMbolization of Intracranial AnEuRysms with
Pipeline™ Embolization Device Clinical Study
Medtronic
Role: PI, 1.5%; Major Goals: Test the efficacy of flow diversion for the treatment of intracranial
aneurysms
1/1/11-3/1/15 Genetic Alterations in Intramedullary Spinal Cord Tumors
Malia’s Cord Foundation
PI: George Jallo
Role: Co-Investigator, 0%; Major Goals: Determine the global mutational profile of spinal
ependymomas and astrocytomas and compare them to their intracranial counterparts.
14
1/1/12-12/31/12 The development of novel diagnostic methods for managing children with brain tumors
Pediatric Brain Tumor Foundation; Vogelstein/Bettegowda (co-PI)
Role: Co-PI, 15%; Major Goals: Develop non-invasive methods of monitoring disease
burden in children with brain tumors.
3/1/12-3/1/13 Circulating Tumor DNA as a Biomarker for Malignant Peripheral Nerve Sheath Tumors
American Association of Neurological Surgeons/Congress of Neurological Surgeons
Spine Section David Kline Peripheral Nerve Research Award
Role: PI; 0% Major Goals: Develop novel blood based biomarkers for patients with
malignant peripheral nerve sheath tumors.
7/1/12-6/30/13 Translational molecular genetics of brain tumors
Johns Hopkins University Clinical Scholars Award
Role: PI, 15%
11/1/12-10/31/13 Therapeutic and Diagnostic Strategies in Oligodendroglioma.
Brain Science Institute Translational Research Grant.
Role: PI, 0%; Major Goals: Develop in vitro and animal models of oligodendroglioma to
test various targeted therapeutics. In addition, develop novel biomarkers for patients with
oligodendrogliomas.
1/1/13-12/31/13 The development of novel diagnostic methods for managing children with CNS tumors
Pediatric Brain Tumor Foundation; Vogelstein/Bettegowda (co-PI)
Role: Co-PI, 15%; Major Goals: Develop non-invasive methods of monitoring disease
burden in children with brain tumors.
7/1/13-6/30/14 Translational molecular genetics of brain tumors
Johns Hopkins University Clinical Scholars Award
Role: PI, 15%
11/1/13-10/30/15 Development of novel personalized biomarkers for individuals with chordoma.
Chordoma Foundation
Role: PI, 0%; Major Goals: Develop blood based tests to track disease burden in individuals
with chordoma.
1/1/14-12/31/14 The development of novel diagnostic methods for managing children with CNS tumors
Pediatric Brain Tumor Foundation; Vogelstein/Bettegowda (co-PI)
Role: Co-PI, 15%; Major Goals: Develop non-invasive methods of monitoring disease
burden in children with brain tumors.
4/1/14-3/31/15 Development of personalized biomarkers for individuals with primary spinal column
neoplasms.
AOSpine North America Young Investigator Research Grant.
Role: PI, 0%; Major Goals: Develop a blood based test to measure disease burden in
individuals with primary spinal column tumors.
6/1/16-5/31/17 Development of personalized biomarkers for individuals with primary spinal column
neoplasms.
AOSpine North America Young Investigator Research Grant.
Role: PI, 0%; Major Goals: Develop a blood based test to measure disease burden in
individuals with primary spinal column tumors.
10/1/12-12/31/17 A Prospective Multicenter Trial of Novo-TTF 100 for High Grade Glioma
Novocure LTD
Role: PI, 0%; Major Goals: Testing efficacy of alternating electrical fields for individuals
with high grade glioma
15
7/1/14-6/30/18 Blood based biomarkers for hereditary cancer syndromes using neurofibromatosis 1 as a
model.
Doris Duke Clinical Scientist Development Award
Role: PI, 15%; Major Goals: Develop a screening test for malignant peripheral nerve sheath
tumors in individuals with Neurofibromatosis 1.
CLINICAL ACTIVITIES
Clinical Focus
My clinical practice is focused on the multi-disciplinary management of individuals with brain and spinal cord
tumors. I perform both open surgical procedures as well as stereotactic radiosurgery. In addition, I offer
comprehensive care for patients with trigeminal neuralgia.
Certification
Licensure
2012-present Maryland, #D74560
2017-present Board Certified, Neurological Surgery
Clinical Service Responsibilities
2012-Present Attending neurosurgeon, Johns Hopkins Hospital
2012-Present Attending neurosurgeon, Johns Hopkins Hospital
2013-Present Neurosurgeon, Baltimore, VA Hospital
Clinical Productivity
Perform on average > 200 surgery and radiosurgery cases per year.
Clinical Draw from outside local/regional area
36% of operative cases are from out-of-state
Clinical Program Building / Leadership 2013-present 1st Johns Hopkins Neurosurgeon to Provide Neurosurgical Care at Maryland, VA Hospital.
2015-present Heading Johns Hopkins Brain Tumor Clinical Practice Improvement Initiative
2015-present Member Neurosurgery/Neurology Appointment and Promotions Committee
2018-present Johns Hopkins Medicine Leadership Development Program
Clinical Demonstration Activities
12/2014 Speaker, Treatment Options for Trigeminal Neuralgia, Trigeminal Neuralgia Association,
Columbia, MD
10/2017 Speaker, Treatment Options for Malignant Brain Tumors, American Brain Tumor Association,
Baltimore, MD
12/2017 Speaker, Treatment Options for Trigeminal Neuralgia, Trigeminal Neuralgia Association,
Columbia, MD
6/2018 Speaker, Career in Medicine to High School Students, National Youth Forum, Baltimore MD
7/2018 Speaker, Career in Medicine to High School Students, National Youth Forum, Baltimore MD
EDUCATIONAL ACTIVITIES
Educational Focus
I teach students, residents and fellows in and out of the operating room on the evaluation and management of
neurosurgical diseases including primary and metastatic brain and spinal tumors, trigeminal neuralgia, and
intracranial trauma. I also mentor students, residents and fellows on neurosurgery related clinical outcomes research
as well as laboratory based efforts studying cancer genetics. I have mentored the spectrum of trainees spanning
undergraduate and medical students, as well as neurosurgical residents and fellows. I also sit on the Neurosurgery
Residency review committee where we evaluate and modify our residency program to meet the evolving needs of
our trainees and maintain compliance with ACGME requirements. I also initiated and oversee the CAST approved
fellowship program at Johns Hopkins in neuro-oncology for neurosurgical residents.
Educational Leadership
2012 - Present Member, Johns Hopkins Neurosurgery Residency Review Committee
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2017- Present Member, Johns Hopkins Physician Scientist Training Program Managing Board
2018 - Present Johns Hopkins Neurosurgery Brain Tumor CAST Fellowship Co-Director
Teaching
Classroom Instruction 6/2013 Speaker, Medical Students, Johns Hopkins School of Medicine Neuro-Oncology Interest Group,
Baltimore, MD, “My Path to Neurosurgery”
12/2017 Speaker, Masters in Public Health, Bloomberg School of Public Health, Baltimore, MD, “Overview
of Brain Tumors in Adults”
5/2018 Speaker, First Year Medical Students, Johns Hopkins University School of Medicine, Baltimore,
MD, “Overview of Brain Tumors in Adults”
12/2018 Speaker, Masters in Public Health, Bloomberg School of Public Health, Baltimore, MD, “Overview
of Brain Tumors in Adults”
5/2019 Speaker, First Year Medical Students, Johns Hopkins University School of Medicine, Baltimore,
MD, “Overview of Brain Tumors in Adults”
Clinical Instruction
In the operating room, I teach all levels of students and residents the surgical management of brain and spinal cord
tumors, trigeminal neuralgia, head trauma and hydrocephalus. I guide residents and students daily on the inpatient
management of neurosurgical problems. Students and residents alike participate in my weekly clinic to learn the
outpatient management of neurosurgical disorders. I also mentor residents to obtain knowledge on stereotactic
radiosurgery and other radiation treatment regimens available for individuals with tumors of the brain and spine. In
addition, I have overseen and participate in our monthly journal club seminars for the residents. I also give several
grand round lectures every year focused on educating residents on various aspects of clinical and research arenas
within neuro-oncology.
CME Instruction
JHMI/Regional
3/05 Speaker, PhD Thesis Defense, Cellular and Molecular Medicine, Johns Hopkins University School of
Medicine - “Bacteriolytic Therapy for Cancer”
1/07 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Developments in the use of an Anaerobic
Bacterium in the Treatment of Solid Tumors”
8/07 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Brainstem Tumors”
4/08 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Torticollis”
12/09 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Intramedullary Spinal Cord Tumors”
4/10 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Blood Based Biomarkers in Cancer”
4/10 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Spinal Cord Tethering Following
Myelomeningocele Repair”
7/10 Speaker, Neuro-Oncology Seminar, Johns Hopkins Hospital, “Blood Based Biomarkers in Cancer”
2/11 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Advances in the Genetic Understanding of
Medulloblastoma”
10/11 Speaker, Neuro-Oncology Seminar, Johns Hopkins Hospital, “Genomic Alterations in Oligodendroglioma”
4/12 Speaker, Helen B. Taussig Young Investigators Day Lecture, Johns Hopkins University School of Medicine,
“A Proposed Genetic Basis for 1p/19q Co-Deletion In Oligodendrogliomas”
6/12 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Neurosurgical Training at Johns Hopkins”
7/12 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Cancer Genetics for the Neurosurgeon”
8/12 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Brain Tumor Emergencies”
11/12 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Biomarkers for Medulloblastoma”
2/13 Speaker, Medical Oncology Grand Rounds, Johns Hopkins Hospital, “Surgical Management of Spinal
Metastases”
1/15 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Updates in Cancer Genetics for the
Neurosurgeon”
2/17 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Updates in Cancer Genetics for the
Neurosurgeon”
17
3/17 Speaker, Prince George’s Hospital, Washington DC, “Surgical and Radiation Management of Brain and
Spinal Cord Tumors”
4/17 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Management of Spinal Cord Tumors”
10/17 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Management of Trigeminal Neuralgia”
12/17 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Updates in Neuro-Oncology”
4/19 Speaker, Neurosurgery Grand Rounds, Johns Hopkins Hospital, “Updates in the Biology and Management
of Chordoma”
National
7/13 Speaker, Audience was physicians from USA, Vokkaligara Parishat of America, Chicago, IL, “Altered
Mental Status – New Guidelines for Evaluation and Treatment”
5/15 Speaker, Audience was pathologists in New York, New York Pathological Society, New York, NY
“Application of Next Generation Sequencing for the Detection of Circulating Tumor DNA”
5/15 Speaker, American Association of Neurological Surgeons, Washington DC, “Somatic Mutations of SUZ12
in Malignant Peripheral Nerve Sheath Tumors”
6/15 Speaker, 2015 Children’s Tumor Foundation Neurofibromatosis Conference, Monterey, CA,
“Liquid Diagnostics: Biomarkers for the Neurofibromatosis”
3/16 Speaker, American College of Radiation Oncology Annual Meeting, Lake Buena Vista, FL, “New
Molecular Categories of Glioma: What You Need to Know to Properly Treat Your Patients Today”
8/16 Speaker, Methodist Hospital, Division of Thomas Jefferson Hospital, Philadelphia PA, “Surgical and
Radiation Treatment Options for Brain Tumors”
3/18 Speaker, American Association of Neurological Surgeons Spine Section Meeting, Orlando FL,
“Molecular Profiling, Detection and Targeting of Spine Tumors”
International
10/15 Moderator, Fourth Bologna-Budapest Spine Meeting on Tumors and Osteoporosis, Bologna, Italy
“Management of spine tumors"
4/16 Moderator, Global Spine Congress 2016, Dubai, UAE, “Novel technologies in spine surgery”
4/17 Speaker, International Precision Oncology and Experimental Therapeutics Congress, Calgary, Canada, “Can
precision oncology and experimental therapeutics be carried out using liquid biopsies?”
8/17 Speaker, National Institute of Neuroscience and Mental Health, Bangalore, India, “Updates to the molecular
classification of brain tumors”
8/17 Speaker, National Institute of Neuroscience and Mental Health, Bangalore, India, “Novel CSF based
biomarkers for individuals with CNS tumors”
8/17 Speaker, Narayana Health System, Bangalore, India, “Novel CSF based biomarkers for individuals with
CNS tumors”
Mentoring
Undergraduate Advisees:
2013-2015 Anvesh Annadanam, BS, currently: Medical Student, Johns Hopkins University
2013-2017 Gabriela Frid, BS Candidate, currently: Undergraduate Student, Johns Hopkins University
2013-2017 Ravi Gaddipati, BS Candidate, currently: Undergraduate Student, Johns Hopkins University
Pre-Doctoral Advisees: 2010-2011 Vivek Mehta, MD, currently: Resident, Department of Neurosurgery, University of Southern
California, Los Angeles
2011-2012 Amit Jain, MD, currently: Fellow, Department of Orthopedic Surgery, Emory University School of
Medicine
2011-2012 Anu Amin, MD, currently: Resident, Department of Neurosurgery, New York Medical College
2012-2015 Yuxuan Wang, BS, currently: MD/PhD Student, Johns Hopkins University School of Medicine
2014-2015 Joanna Wang, MD, currently: Medical Student, Johns Hopkins University School of Medicine
2014-present Ann Liu, MD, currently: Medical Student, Wake Forest University School of Medicine
2015-present Timour Al-Khindi, currently: MD/PhD Student, Johns Hopkins University School of Medicine
2015-present Eric Xe, currently: MD Student, Johns Hopkins University School of Medicine
2016-present Josh Cohen, BS, currently: PhD Student, Johns Hopkins University School of Medicine
18
2017-present Ashley Cook, BS, currently: PhD Student, Johns Hopkins University School of Medicine
2017-present Jeffrey Ehresman, BS, currently: MD Student, Johns Hopkins University School of Medicine
2017-present Zach Penningtion, BS, currently: MD Student, Johns Hopkins University School of Medicine
Post-Doctoral Advisees:
2012-present Ming Zhang, Post-doctoral Fellow, Department of Oncology, Johns Hopkins University
2012-2015 Yuchen Jiao, MD/PhD, Department of Oncology, Johns Hopkins University, currently: Professor,
National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College
2013-15 Larry Lo, MD, Neurosurgery Resident, Johns Hopkins Hospital, currently: Assistant Professor,
Johns Hopkins University
2014-16 Rory Goodwin, MD/PhD, Neurosurgery Resident, Johns Hopkins Hospital, currently: Assistant
Professor, Duke University
2014-present Karisa Schreck, MD/PhD, Neuro-oncology Fellow, Johns Hopkins Hospital/NIH, currently:
Assistant Professor, Johns Hopkins University
2015-present Tomas Garzon, Neurosurgery Resident, Johns Hopkins Hospital, currently: Fellow, University of
Pittsburg
2017-present Rajiv Iyer, MD, Neurosurgery Resident, Johns Hopkins Hospital
2018-present Christopher Douville, PhD, Post-doctoral Fellow, Johns Hopkins University School of Medicine
2018-present Jonathan Dudley, MD, Post-doctoral Fellow, Johns Hopkins University School of Medicine
2018-present Christina Jackson, MD, Resident, Johns Hopkins University School of Medicine
2019-present Jordina Rancon, MD, Resident, Johns Hopkins University School of Medicine,
2019-present Dimitrios Mathiois, MD, Resident, Johns Hopkins University School of Medicine
RESEARCH ACTIVITIES
My clinical research focus is based on understanding how neurosurgical interventions alter patient outcomes. My
laboratory based research is focused on understanding the genetic basis of central nervous system tumors and
applying that knowledge for clinical benefit. We have discovered several of the pivotal genes involved in a myriad
of CNS cancers, including CIC/FUBP1 in oligodendroglioma, hTERT for GBM, SUZ12 in malignant peripheral
nerve sheath tumors and DMD in olfactory neuroblastoma. We are also actively interesting in translating these
genetic discoveries for diagnostic benefit by developing sensitive PCR based assays capable of detecting released
tumor DNA in the circulation and a variety of biofluids such as cerebrospinal fluid, saliva and pap smears.
Research Program Building/Leadership
Scientific Lead for AOSpine Tumor Knowledge Forum – non-profit organization aimed at disseminating knowledge
on the diagnosis and management of spinal tumors worldwide. We have been able to develop an international
network of collaborators to study rare spinal neoplasms, which has resulted in discovering a link between germline
and somatic variants and outcomes for individuals with chordoma.
I am also the co-chair of the biomarker committee for the Response Evaluation in Neurofibromatosis and
Schwannomatosis International Collaboration (REiNS) consortium. REiNS is an international network of
physicians, researchers and patient advocates dedicated to generating guidelines for the management of individuals
with neurofibromatosis (NF). As a part of this multi-national group, we are developing consensus statements on how
to best treat and monitor individuals with NF.
Inventions, Patents, Copyrights
5/05 United States Patent WO2005039491A2, “Improved Combination Bacteriolytic Therapy for the Treatment
of Tumors”
3/08 United States Patent US7344710, “Combination Bacteriolytic Therapy for the Treatment of Tumors”
5/12 United States Patent US 11/629,607, “Imaging Infection with Compounds the Bind to Thymidine Kinase"
07/12 United States Provision Patent US14/233,296, “Oligodendroglioma driver genes”
9/12 United States Provision Patent US14/347,463, “Methods and composition for detecting infections”
4/15 United States Provisional Patent US14/439,041, “Papanicolaou Test for Ovarian and Endometrial Cancers”
7/15 United States Provisional Patent US62/192,424, “Detection of Tumor-Derived DNA in Cerebrospinal Fluid”
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8/15 United States Provisional Patent US14/765,692, “TERT Promoter Mutations in Gliomas and a Subset of
Tumors”
1/19 United States Patent US15/071,800, “Use of the ZMIZ1 Marker in Directing Treatment and Predicting
Survival in Cancer”
SYSTEM INNOVATION AND QUALITY IMPROVEMENT ACTIVITIES
System Innovation Focus
I am focused on improving health delivery for our patients with brain tumors. In particular I am interested in
improving safety and satisfaction in those individuals undergoing a craniotomy for resection of a brain tumor.
System Innovation and Quality Improvement Efforts within JHMI:
2013-present Working with neuropathology and neurosurgery to develop streamline tumor banking protocol.
2015-present Physician lead for Johns Hopkins Brain Tumor Clinical Community
2018-present Department of Neurosurgery Physician Advisor
ORGANIZATIONAL ACTIVITIES
Institutional Administrative Appointments 2016-present Director of Johns Hopkins Meningioma Center
2018-present Physician Advisor, Department of Neurosurgery
Editorial Activities
Editorial Board Appointments:
2015-2018 Annals of Surgical Oncology, Editorial Board Member
2015-present Operative Neurosurgery, Editorial Board Member
Journal Peer Review Activities
2009-present Molecular Imaging, Ad Hoc Reviewer
2010-present Neurosurgery, Ad Hoc Reviewer
2011-present International Journal of Medical Microbiology, Ad Hoc Reviewer
2012-present Annals of Surgical Oncology, Ad Hoc Reviewer
2012-present Journal of Neurosurgery, Ad Hoc Reviewer
2012-present Neurosurgery, Ad Hoc Reviewer
2013-present Child’s Nervous System, Ad Hoc Reviewer
2013-present Science, Ad Hoc Reviewer
2013-present Cancer Research, Ad Hoc Reviewer
2014-present Nature Communications, Ad Hoc Reviewer
2014-present Oncotarget, Ad Hoc Reviewer
2015-present Clinical Cancer Research, Ad Hoc Reviewer
2015-present Neuro-oncology, Ad Hoc Reviewer
2015-present Journal of Neuro-Oncology, Ad Hoc Reviewer
2016-present New England Journal of Medicine, Ad Hoc Reviewer
Professional Societies
2006-Present American Association of Neurological Surgeons (AANS)
2011-Present American Association of Cancer Researchers (AACR)
2014-Present Congress of Neurological Surgeons (CNS)
2018-Present Neurosurgical Society of America (NSA)
2019-Present American Society of Clinical Investigators (ASCI)
Advisory Committees, Review Groups/Study Sections
2008-2010 Elected to Young Neurosurgeons Committee (YNC) of AANS
2011 YNC liaison to the Tumor Section of AANS
2012-2013 Associate Scientific Advisor, Science Translational Medicine
2012-present AO Spine Tumor Knowledge Forum Steering Committee
2017-present ECOG-ACRIN Biomarker Steering Committee
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2017-present Response Evaluation in Neurofibromatosis and Schwannomatosis International Collaboration
(REiNS), co-Chair Biomarkers Subgroup
2018-present Scientific Board Member, B*Cured Foundation
2019 Reviewer, R21 Program, NIH Center for Scientific Review, Washington DC, Feb 6, 2018.
2019 Reviewer, R21 Program, NIH Center for Scientific Review, Washington DC, Feb 5, 2019.
2019 Reviewer, B*Cured Foundation Funding Program, Baltimore MD, May 6, 2018
2019 Reviewer, Doris Duke Charitable Foundation, Clinician Scientist Development Award, May 17,
2019
2019 Reviewer, U01 Program, NIH Center for Scientific Review, Washington DC, July 2, 2019
Conference Organizer
National
9/16 Tumor Satellite Meeting, Congress of Neurological Surgeons, San Diego CA
Session Chair
National
11/13 Circulating Nucleic Acids in Plasma and Serum Meeting, Baltimore MD, “Legal, Regulatory and Clinical
Considerations of CNAPS”.
8/14 Next Generation Diagnostics Summit, Washington DC, “Applications of Cell Free Tumor DNA in the
Clinic”
11/18 Society of Neuro-Oncology, Sunrise Session Chair, “Liquid Biopsies for Brain Tumors”
International
5/15 Session on Spinal Oncology, Global Spine Congress 2015, Buenos Aires, Argentina
5/18 Course Director, Essentials of Spinal Oncology, Global Spine Congress 2018, Singapore
RECOGNITION
Awards, Honors
1994 Benjamin N. Duke Scholarship: Full scholarship given to 5-10 top students from North and South Carolina
1994 Watson IBM Scholarship for Scholastic Excellence: Annual award given for academic achievement to
students who are children of IBM employees
2005 Alpha Omega Honor Society, Johns Hopkins University School of Medicine
2005 Oncology Fellows Research Award: First place for translational research in oncology, Johns Hopkins
University School of Medicine
2005 Hunterian Neurosurgery Research Award, Johns Hopkins University School of Medicine
2008 Sherman Award for Neurosurgery Resident Achievement, Johns Hopkins University School of Medicine
2009 American Brain Tumor Associate Research Fellowship
2011 Harvey Cushing Award for Neurosurgery Research Excellence, Johns Hopkins University School of
Medicine
2012 David Kline Research Award, AANS/ CNS Spine Section
2012 Helen B. Taussig Award, Given for Most Outstanding Research by Post-Doctoral Fellow, Johns Hopkins
University School of Medicine
2012 Richard S. Ross Clinician Scientist Award Recipient, given annually to the applicant with the best
application, Johns Hopkins University School of Medicine
2012 Irving Sherman Travel Award, Johns Hopkins University School of Medicine
2012 Genome Technology’s Seventh Annual “Tomorrow’s PI’s”; Given to Most Promising
Young Investigators in the Country
2015 Sanford Larson Award for Best Peripheral Nerve/Spine Paper, AANS
2016 Reinhoff Scholar Award
2017 American Association of Cancer Researchers, Team Science Award for “Liquid biopsies”
2019 American Society for Clinical Investigators
2019 Visiting Scholar, NCI Neuro-oncology Branch
Invited Talks, Panels
21
JHMI/Regional
9/12 Moderator, Audience was neuro-oncology clinicians and researchers from around world, Basic Science
Session, 11th Annual International Neuro-Oncology Update, Baltimore MD
9/12 Speaker, Audience was neuro-oncology clinicians and researchers from around world, 11th Annual
International Neuro-Oncology Updates, Baltimore, MD
3/13 Speaker, Neuro-Oncology Research Conference, Johns Hopkins Hospital, “Molecular Classification of
Brain Tumors”
10/13 Speaker, Translational Research Conference, Johns Hopkins Oncology Center, Baltimore, MD, “Blood
based biomarkers for the detection and monitoring of human malignancies”
1/14 Speaker, Clinical Neurosciences Seminar, Baltimore MD. “Circulating Tumor DNA as a Biomarker for
Human Malignancies”.
2/15 Speaker, NCCU Lecture Series, Johns Hopkins Hospital; “Circulating Tumor DNA as a Biomarker for Solid
Malignancies”.
2/15 Speaker, Inaugural Indo-US Translational Neuroscience Symposium, Baltimore MD; “Cell Free Tumor
DNA for the Management of Central Nervous System Tumors”
6/16 Speaker, Assistant Professors Series; “Translating our Genetic Understanding of Cancer into Personalized
Biomarkers”
8/16 Speaker, Radiation Oncology Resident Research Seminar, “Management of Malignant Gliomas”
3/17 Speaker, Neuroscience in Intensive Care International Symposium, Washington DC, “Towards a Molecular
Taxonomy for Cancer”
11/17 Speaker, A Woman’s Journey, Baltimore, MD, “Liquid biopsy for cancer”
2/19 Speaker, National Cancer Institute, Bethesda, MD, “CSF Based Liquid Biopsies for CNS Tumors”
2/19 Speaker, NCI Pancreatic Cancer Consortium Meeting, Bethesda MD, “Early Detection Strategies in
Pacreatic Cancer”
5/19 Speaker, Annual Health Care Journalism Meeting, Baltimore MD, ‘Treatment and Advances in Brain
Tumors”
5/19 Speaker, Plastic Surgery Research Council Annual Meeting, Baltimore MD, “Circulating Tumor DNA as a
Biomarker in Human Malignancies”
National
3/04 Speaker, American Association of Cancer Researchers National Meeting, “Bacteriolytic Therapy for
treatment of Solid Malignancies”
12/08 Speaker, Pediatric Section of American Association of Neurosurgeons, “Choroid Plexus Tumors: A 20 Year
Institutional Experience”
3/11 Speaker, Neurosurgery Grand Rounds, Emory University, “Circulating Tumor DNA as a Personalized
Biomarker for Patients with Solid Tumor”
12/11 Speaker, Department of Neuro-Oncology, Moffitt Cancer Center, “Translating Genomics into Personalized
Biomarkers”; “Circulating Tumor DNA as Blood Based Biomarkers in Patients with Solid Tumors”
10/12 Speaker, 11th Annual Frye Halloran Brain Tumor Symposium, Massachusetts General Hospital, Boston MA,
“CIC Mutations in Oligodendrogliomas”
1/13 Speaker, Low Grade Glioma Meeting, San Francisco, CA, “Molecular Classification of Low Grade
Gliomas”
3/13 Speaker, Chordoma Foundation Biannual Workshop, Boston, MA, “AOSpine Tumor Biobanking”
3/13 Speaker, Chordoma Foundation Biannual Workshop, Boston, MA, “C. novyi-NT Cancer Therapeutic”
5/13 Speaker, Pediatric Brain Tumor Foundation Annual Meeting, Ft. Lauderdale, FL, “Novel Diagnostics
Methods for Children with Brain Tumors”
5/13 Speaker, Pediatric Brain Tumor Foundation Annual Meeting, Ft. Lauderdale, FL, “Hot Topics in Pediatric
Neuro-Oncology”
9/13 Speaker, Accelerate Brain Cancer Cure and National Cancer Institute Meeting on Glioblastoma.
Washington DC, “Breakout Session Summary on Genomic Medicine to Advance Glioblastoma”
2/14 Speaker, Association for Collaborative Spine Research. San Diego, CA. “Prognostic Significance of T Gene
snp2305089 in Individuals with Spinal Column Chordoma”.
2/14 Speaker, Association for Collaborative Spine Research. San Diego, CA. “Aneurysmal Bone Cysts of the
Spine: Treatment Options and Considerations”.
22
3/14 Speaker, American Association of Neurological Surgeons/Congress of Neurological Surgeons Spine Section
Meeting. Orlando, FL. “Circulating Tumor DNA as a Biomarker for Malignant Peripheral Nerve Sheath
Tumors”.
5/14 Speaker, Pediatric Brain Tumor Foundation Annual Meeting, San Antonio, TX, “Development of Novel
Personalized Biomarkers for Individuals with Brain Tumors”.
7/14 Speaker, 20th International Meeting on Brain Tumor Research and Therapy, Lake Tahoe NV, “Detection of
circulating tumor DNA in early and late stage human malignancies”.
8/14 Speaker, 2014 Next Generation Diagnostic Summit, Washington, DC, “Detection of circulating tumor DNA
in early and late stage human malignancies”.
12/14 Speaker, Biomed Valley Discoveries Investigator Meeting, Kansas City, KS, “Future Clinical Trials for
Clostridium noyi-NT”.
2/15 Speaker, Invited Guest Lecture at Illumina, San Diego, CA, “Detection of Cell Free Tumor Derived DNA in
Human Malignancies”.
2/15 Speaker, Pathology Grand Rounds, City of Hope Cancer Center, Los Angeles, CA, “Detection of Cell Free
Tumor Derived DNA in Human Malignancies”.
2/15 Keynote Speaker, 2015 Molecular Medicine Tri-Conference, Circulating Cell-Free DNA Meeting, San
Francisco, CA, “Detection of Circulating Tumor DNA in Early and Late Stage Human Malignancies.
4/15 Speaker, Annual Doris Duke Clinician Scientist Awardee Meeting, Chicago, IL, “Somatic Mutations of
SUZ12 in Malignant Peripheral Nerve Sheath Tumors”
4/15 Speaker, Neurosurgical Society of America, Newport Beach, CA.“Prognostic Significance of the T gene
SNP rs2305089 in Individuals with Spinal Column Chordoma”
5/15 Speaker, Association for Collaborative Spine Research Meeting, Miami, FL, “Molecular Projects in Spinal
Oncology”
6/15 Speaker, 2015 Children’s Tumor Foundation Neurofibromatosis Conference, Monterey, CA, “Liquid
Diagnostics: Biomarkers for the Neurofibromatoses”
8/15 Speaker, 2015 Next Generation Diagnostic Summit, Washington DC, “Plasma Based Detection of Tumor
Derived DNA in Human Malignancies”
4/16 Speaker, A Woman’s Journey, Sarasota, FL, “Liquid biopsy for cancer”
4/16 Speaker, A Woman’s Journey, St. Petersburg, FL, “Liquid biopsy for cancer”
4/16 Speaker, A Woman’s Journey, Tampa, FL, “Liquid biopsy for cancer”
7/16 Speaker, Chordoma Foundation Meeting, Boston MA, “Use of Circulating Tumor DNA as a Biomarker for
Individuals with Chordoma”
7/16 Speaker, 2nd qPCR and Digital PCR Congress, Philadelphia PA, “Tumor Derived Cell Free DNA as a
Diagnostic Tool for Human Malignancies”
9/16 Speaker, AANS/CNS Tumor Satellite Symposium, San Diego CA, Tumor Derived DNA in the CSF as a
Biomarker for CNS Neoplasms
10/16 Panelist, Cowen and Company 5th Annual MedTools Unlocked Conference, New York, NY, “Liquid Biopsy
& Beyond – Emerging Tools for Cancer Screening and Management”
2/17 Visiting Professor, Weill-Cornell University School of Medicine, New York, NY, “Tumor Derived DNA as
a Biomarker for Individuals with Cancer”.
2/17 Speaker, Molecular Medicine Tri-Conference, San Francisco CA, “Tumor Derived DNA as a Diagnostic
Tool for Human Malignancies”
2/17 Speaker, A Woman’s Journey, Naples, FL, “Liquid biopsy for cancer”
7/17 Speaker, 3rd qPCR and Digital PCR Congress, Philadelphia PA, “Tumor Derived Cell Free DNA as a
Diagnostic Tool for Human Malignancies”
9/17 Speaker, Ian’s Friends Foundation Meeting, Atlanta, GA, “Development of novel diagnostic strategies for
children”
10/17 Speaker, ECOG-ACRIN 2017 Annual Meeting, Orlando FL, “Circulating Tumor DNA: Current
Technology and Applications to Colon Cancer
10/17 Speaker, ECOG-ACRIN 2017 Annual Meeting, Orlando FL, “Liquid Biopsy Applications for Brain
Tumors”
12/17 Speaker, Neuro-Oncology Grand Rounds, Moffitt Cancer Center, Tampa, Fl, “Liquid Biopsy Approaches in
the Management of Human Cancers”
2/18 Speaker, Molecular Medicine Tri-Conference, San Francisco CA, “Tumor Derived DNA as a Diagnostic
Tool for Human Malignancies”
23
3/18 Speaker, Spine Summit, Orlando FL, “Molecular Profiling, Detection and Targeting of Spine Tumors”
6/18 Speaker, Neurosurgical Society of America, Jackson Hole, WY, “TERT Promoter Mutations in Primary
Spinal Column Sarcomas”
11/18 Speaker, MD Anderson Distinguished Seminar Series, Houston, TX “Multi-analyte Tests for the Detection
and Monitoring of Cancers”.
11/18 Speaker, Society for Neuro-oncology, New Orleans, LA, “CSF Based Liquid Biopsies for Brain Tumors”.
3/19 Speaker, Molecular Medicine Tri-Conference, San Francisco CA, “Multi-analyte Assays for the Detection
and Monitoring of Cancers”
4/19 Speaker, EDP Summit, Boston, MA, “Cancer-Seek, A Multi-Analyte Blood Test for the Earlier Detection of
Cancers”
6/19 Speaker, Wyss Family Think Tank, Columbus, OH, “Released Tumor DNA to Detect and Monitor Cancers”
International
7/10 Speaker, 9th International Meeting, Updates in Neuro-Oncology Brain Tumor Symposium, Tuscany
Italy;“Blood Based Biomarkers, Applications to Neuro-Oncology.”
6/11 Speaker, Labatt Brain Tumour Research Centre Guest Lecture, University of Toronto, “Translating
Genomics into Personalized Biomarkers”
3/12 Speaker, AO Spine Knowledge Forum Steering Committee, “Spinal Tumor Biobanking”, Banff Canada
9/12 Speaker, 2nd Annual Bologna-Budapest Spine Meeting, Budapest, Hungary, “Genetics of Primary Spinal
Column Tumors”
6/14 Speaker, Neurosurgical Society of America, St. Andrews, New Brunswick Canada, Speaker, “Translational
molecular profiling of oligodendrogliomas”.
6/14 Speaker, Neurosurgical Society of America, St. Andrews, New Brunswick Canada, “The promise of
personalized cancer care”.
4/15 Speaker, AOSpine North America Fellows Forum, Banff, Canada, “Circulating Tumor DNA for the
Detection of Spinal Malignancies”
5/15 Speaker, Global Spine Congress 2015, Buenos Aires Argentina, “Prognostic significance of T gene SNP
rs2305089 in individuals with spinal column chordoma”.
5/15 Speaker, Global Spine Congress 2015, Buenos Aires Argentina, “Outcomes following surgical intervention
for impending and gross instability caused by multiple myeloma in the spinal column”.
10/15 Speaker, 4th Bologna-Budapest Spine Meeting on Tumors and Osteoporosis, Bologna, Italy, “Molecular
studies associated with primary and metastatic lesions”
10/15 Speaker, 4th Bologna-Budapest Spine Meeting on Tumors and Osteoporosis, Bologna, Italy,
“Multidisciplinary management of spine metastases, to reduce morbidity and improve outcomes
4/16 Speaker, Global Spine Congress 2016, Dubai, UAE, “Clinical Decision Making: Integrating Advances in
the Molecular Understanding of Primary Spine and Metastatic Tumors”
11/17 Speaker, Liquid Biopsies for next-generation diagnostics, Uppsala, Sweden, “Circulating Tumor DNA as a
Biomarker for Human Cancers”
5/18 Speaker, Global Spine Congress 2018, Singapore, “Treatment of Intradural Spinal Tumors”
6/18 Speaker, American Society of Neuro-Radiology, Vancouver Canada, “Why I need fMRI: Neurosurgeon’s
perspective”.
11/18 Speaker, Seventh Annual BMB Spine Meeting, Milan, Italy, “The Molecular Features of Spine Tumors and
their Therapeutic Relevance”.
12/18 Speaker, EMBL-EBI Liquid Biopsy Conference, Cambridge, UK. “Multi-Analyte Tests for the Detection
and Monitoring of Cancers”
6/29 Speaker, Neurosurgical Society of America, Banff, Canada. “Genomic Analysis Identifies Frequent
Deletions of dystrophin in olfactory neuroblastoma”
9/19 Speaker, Advances in Thoracic Surgery, Oncology and Pulmonology (ATSOP) Workshop and Congress,
Singapore, “Circulating Tumor DNA Applications for Lung Cancer”
OTHER PROFESSIONAL ACCOMPLISHMENTS
Posters
1997 Levin ED, Bettegowda C. Nicotinic NMDA interactions with working and reference memory. Soc
Neurosci. 1997; 23: 216
24
1998 Levin ED, Bettegowda C et al. AR-R 17779, an a7 nicotinic agonist improves learning and memory in
rats. Soc Neurosci. 1998;24: 183
2000 Haroun R, Bettegowda C, Li K and Brem H. Effects of Col-3, an anti-angiogenesis agent on rat brain
endothelial cell proliferation. Am Assoc Neurolog Surgeons. San Francisco, CA
2000 Haroun R, Li K, Bettegowda C, Crumpler E, Landa J and Brem H. In vivo toxicity study of topoisomerase
II inhibitor 9-chloro-2-methyl-ellipticinium acetate via local intracranial delivery. Am Assoc Neurolog
Surgeons. San Francisco, CA
12/09 Mehta V, Bettegowda C, Jallo G. Intramedullary tumoral calcinosis. Am Assoc Neurolog Surgeons,
Section on Pediatric Neurosurgery.
12/09 Mehta V, Bettegowda C, Jallo G. Intramedullary tumoral calcinosis. AANS/CNS Section on Pediatric
Neurosurgery
10/10 Mehta V, Bettegowda C, Jallo G, Ahn E. Impact of tethered cord release on symptoms of Chiari II
malformation in children born with a myelomeningocele. Congress of Neurological Surgeons Annual
Meeting, San Francisco, CA
10/11 Ononiwu C, Mehta V, Bettegowda C, Jallo G. Pediatric Spinal Glioblastoma Multiforme. Congress of
Neurological Surgeons Annual Meeting. Washington, DC
4/13 Fisher C, Boriani S, Varga PP, Rhines LD, Bilsky MH, Dekutoski MB, Fehlings MG, Reynolds JJ,
Williams RP, Chou D, Berven S, Quraishi NA, Bettegowda C, Gokaslan ZL. A novel model for rare and
often neglected neoplastic conditions. Global Spine Congress 2013, Hong Kong 3/14 Lo L, Puvanesarajah V, Germscheid N, Chou D, Fisher C, Rhines LD, Williams RP, Boriani S, Gokaslan
ZL, Bettegowda C. Aneurysmal Bone Cysts Of The Spine: Treatment Options And Considerations.
AANS/CNS Section on Disorders of the Spine and Peripheral Nerves Annual Meeting. Orlando, FL
4/14 Bettegowda C, Sausen M, Leary R, Kinde I, Agrawal N, Bartlett B, Wang H, Luber B, Kinzler K,
Vogelstein B, Papadopoulos N, Diaz L. Detection of circulating tumor DNA in early and late stage human
malignancies. American Association of Cancer Researchers
4/14 Varga, P, Fisher C, Rhines L, Gokaslan Z, Boriani S, Lazaray A, Wang WL, Germscheid N, Yip S,
Bettegowda C. Prognostic significance of T gene SNP rs2305089 in Individuals with Spinal Column
Chordoma. American Association of Cancer Researchers
4/14 Fisher CG, Versteeg A, Boriani S, Varga PP, Dekutoski MB, Gokaslan ZL, Williams RP, Reynolds JJ,
Fehlings MG, Bettegowda C, Kawahara N, Rhines LD. Chondrosarcomas of the spine: prognostic variables
for local recurrence and mortality in a multicenter study. 82nd American Association of Neurological
Surgeons Annual Scientific Meeting, San Francisco, CA
4/14 Rhines LD, Dirks MS, Boriani S, Luzzati A, Fehlings MG, Fisher CG, Dekutoski MB, Williams R, Quraishi
NA, Gokaslan ZL, Bettegowda C, Kawahara N, Varga PP. Ewing’s sarcoma of the spine: prognostic
variables for recurrence and survival in surgically treated patients. 82nd American Association of
Neurological Surgeons Annual Scientific Meeting, San Francisco, CA
4/14 Quraishi NA, Boriani S, Varga P, Luzzati A, Gokaslan ZL, Fehlings MG, Fisher C, Dekutoski M, Rhines L,
Reynolds J, Bettegowda C, Kawahara N, Williams R. A multi-center retrospective cohort study of spinal
osteoid osteomas: surgical treatment and local recurrence results. 82nd American Association of
Neurological Surgeons Annual Scientific Meeting, San Francisco, CA
4/14 Varga PP, Macki M, Bydon M, Boriani S, Fisher CG, Rhines LD, Chou D, Luzzati A, Reynolds JJ,
Kawahara N, Bettegowda C, Sciubba D, Wolinsky JP, Gokaslan ZL. Long-term outcomes in primary spinal
osteochondroma: a multicenter center study of 27 patients. 82nd American Association of Neurological
Surgeons Annual Scientific Meeting, San Francisco, CA, USA
4/14 Zamorano JJ, Fehlings M, Nater A, Tetreault L, Varga P, Gokaslan Z, Boriani S, Fisher C, Rhines L,
Bettegowda C, Kawahara N, Chou D. Local recurrence risk factors after surgical resection of spine
schwannomas: analysis of 169 patients from a multicenter international database. 82nd American
Association of Neurological Surgeons Annual. San Francisco, CA
4/14 Quraishi NA, Boriani S, Varga P, Luzzati A, Gokaslan ZL, Fehlings MG, Fisher C, Dekutoski M, Rhines L,
Reynolds J, Bettegowda C, Kawahara N, Williams R. A multi-center retrospective cohort study of spinal
osteoid osteomas: surgical treatment and local re-currence results. BritSpine, Warwick, U.K.
5/15 Clarke M, Molina C, Fourney D, Fisher C, Gokaslan Z, Schmidt M, Rhines L, Fehlings M, Laufer I, Patel S,
Rampersaud R, Reynolds J, Chou D, Bettegowda C, Mendel E, Weber M, Sciubba D. Systematic Review
of Surgical Treatment Outcomes of Prostate Metastases to the Spine. Global Spine Congress 2015, Buenos
Aires, Argentina
25
Podium Presentations
10/07 Than KD, Woodworth GF, Bettegowda C, Mcgirt MJ, Jallo GI, Rigamonti D. Adolescent Age Is An
Independent Predictor Of Improved Outcome Following Endoscopic Third Ventriculostomy For The
Treatment Of Hydrocephalus Congress of Neurological Surgeons Annual Meeting. San Diego CA
10/09 Liauw J, Hoang S, Bettegowda C, Frazier JL, Mcgirt MJ, Lim M. Glomus Jugulare Tumors: Radiosurgical
Treatment And Outcomes. Congress Of Neurological Surgeons Annual Meeting. New Orleans, LA
2/13 Fisher C, Boriani S, Varga P, Fehlings M, Bilsky M, Dekutoski M, Luzzati A, Williams R, Berven S, Chou
D, Quraishi N, Rhines L, Bettegowda C, Gokaslan Z. A novel scientific model for rare and often neglected
neoplastic conditions. 13th Annual Scientific Conference of the Canadian Spine Society, Mont-Tremblant,
QC, Canada
3/13 Fisher C, Goldschlager T, Boriani S, Varga P, Fehlings MG, Bilsky M, Dekutoski M, Luzzati A, Williams
R, Berven S, Chou D, Quraishi N, Rhines L, Bettegowda C, Gokaslan Z. A novel scientific model for rare
and often neglected neoplastic conditions. 11th Annual AOSpine North America Fellows Forum, Banff, AB,
Canada
5/13 Fisher C, Boriani S, Varga PP, Fehlings M, Bilsky M, Dekutoski M, Luzzati A, Williams R, Berven S, Chou
D, Reynolds J, Quraishi N, Rhines L, Bettegowda C, Gokaslan Z. A novel evidence based model for rare
and often neglected neoplastic conditions. Third Charite Spine Tumor Days, Berlin Germany
7/13 Fisher C, Fehlings M, Bilsky M, Dekutoski M, Luzzati A, Williams R, Berven S, Quraishi N, Rhines L,
Bettegowda C, Gokaslan Z. A novel scientific model for rare and often neglected neoplastic conditions:
AOSpine knowledge forum tumor international dataset for primary tumors of the spine. 20th International
Meeting on Advanced Spine Techniques, Vancouver, BC, Canada
10/13 Reynolds J, Fisher C, Boriani S, Varga PP, Fehlings MG, Bilsky MH, Dekutoski MB, Rhines L,
Bettegowda C, Gokaslan Z. A novel scientific model for rare and often neglected neoplastic conditions.
EuroSpine 2013, Liverpool, UK
10/13 Fisher C, Boriani S, Varga PP, Fehlings MG, Bilsky MH, Dekutoski MB, Williams RP, Berven SH, Chou D,
Reynolds JJ, Quraishi NA, Rhines LD, Bettegowda C, Gokaslan ZL. A novel scientific model for rare and
often neglected neoplastic conditions: AOSpine International Knowledge Forum Tumor database for primary
tumors of the spine. North American Spine Society (NASS) 28th Annual Meeting, New Orleans, LA
1/14 Varga P, Macki M, Bydon M, Sciubba D, Wolinsky JP, Boriani S, Bettegowda C, Chou D, Fisher CG,
Luzzati A, Reynolds JJ, Germscheid NM, Zadnik P, Rhines LD, Gokaslan ZL, AOSpine Knowledge Forum
Tumor. Long-term outcomes in primary, spinal osteochondroma: a multicenter study of 27 patients.
Association for Collaborative Spine Research Meeting, San Diego, CA
1/14 Fisher CG, Boriani S, Varga PP, Rhines LD, Bilsky MH, Dekutoski MB, Fehlings MG, Reynolds J,
Williams R, Chou D, Quraishi NA, Bettegowda C, Gokaslan ZL, AOSpine Knowledge Forum Tumor. The
new frontier for research and management of primary tumors of the spine. Association for Collaborative
Spine Research Meeting, San Diego, CA
2/14 Goldstein C, Varga P, Gokaslan Z, Boriani S, Luzzati A, Williams R, Rhines L, Fisher C, Chou D,
Dekutoski M, Quraishi N, Bettegowda C, Kawahara N, Fehlings M. Hemangiomas of the spine: results of
surgical management and prognostic variables for local recurrence and mortality in a multicenter study.
Combined meeting with the Canadian Spine Society and the New Zealand Spine Society 2014, Lake Louise,
AB, Canada
2/14 Fehlings M, Zamorano JJ, Nater A, Tetreault L, Varga P, Gokaslan Z, Boriani S, Fisher C, Rhines L,
Bettegowda C, Kawahara N, Chou D. Local recurrence risk factors after surgical resection of spine
schwannomas: analysis of 169 patients from a multicenter international database. Combined meeting with
the Canadian Spine Society and the New Zealand Spine Society 2014, Lake Louise, AB, Canada
2/14 Goldstein C, Varga P, Gokaslan Z, Boriani S, Luzzati A, Williams R, Rhines L, Fisher C, Chou D,
Dekutoski M, Quraishi N, Bettegowda C, Kawahara N, Fehlings M. Hemangiomas of the spine: results of
surgical management and prognostic variables for local recurrence and mortality in a multicenter study.
Combined meeting with the Canadian Spine Society and the New Zealand Spine Society 2014, Lake Louise,
AB, Canada
2/14 Fisher CG, Versteeg A, Boriani S, Varga PP, Dekutoski MB, Gokaslan ZL, Williams RP, Reynolds JJ,
Fehlings MG, Bettegowda C, Kawahara N, Rhines LD. Chondrosarcomas of the spine: prognostic variables
for local recurrence and mortality in a multicenter study. Combined meeting with the Canadian Spine
Society and the New Zealand Spine Society 2014, Lake Louise, AB, Canada
26
3/14 Goldstein CL, Varga , Gokaslan ZL, Boriani S, Luzzati A, Williams RP, Rhines LD, Fisher C, Chou D,
Dekutoski MD, Quraishi NA, Bettegowda C, Kawahara N, Fehlings MG. Hemangiomas Of The Spine:
Results Of Surgical Management And Prognostic Variables For Local Recurrence And Mortality In A
Multicenter Study. AANS/CNS Section On Disorders Of The Spine And Peripheral Nerves Annual Meeting.
Orlando, FL
3/14 Sciubba DM, Mcloughlin GS, McGirt MJ, Bettegowda C, Jagannathan J, Fourney DR, Gokaslan ZL,
Wolinsky JP, Witham TF. Postoperative Infection Of The Instrumented Spine: A Review Of 1,332
Procedures Over 5 Years. AANS/CNS Section On Disorders Of The Spine And Peripheral Nerves Annual
Meeting. Phoenix, AZ
3/14 Puvanesarajah V, Lo L, Liauw J, Bettegowda C, Sciubba DM, Wolinsky JP, Gokaslan ZL, Rigamonti D,
Redmond K, Kleinberg L, Lim M. Johns Hopkins Hospital Initial Experience With Stereotactic
Radiosurgery Of Spinal Tumors. AANS/CNS Section On Disorders Of The Spine And Peripheral Nerves
Annual Meeting. Orlando, FL
4/14 Zadnik P, Varga P, Bettegowda C, Fisher C, Fehlings M, Quraishi N, Luzzati A, Rhines L, Wolinsky JP,
Sciubba D, Dekutoski M, Kawahara N, Boriani S, Gokaslan Z. Survival and recurrence following resection
of chordoma in the mobile spine: results of 171 patients from the AOSpine Primary Tumor Knowledge
Forum. 82nd American Association of Neurological Surgeons Annual Scientific Meeting, San Francisco, CA
4/14 Williams R, Williams R, Sowman B, Boriani S, Varga PP, Luzzati A, Gokaslan Z, Fehlings M, Fisher C,
Dekutoski M, Rhines L, Reynolds J, Bettegowda C, Kawahara N, Quraishi NA. Spinal osteoid osteoma: a
multicentre retrospective cohort study comparison of results with appendicular osteoid osteoma. Spine
Society of Australia Annual Scientific Meeting, Brisbane, Australia
5/14 Varga PP, Fisher CG, Rhines LD, Gokaslan ZL, Boriani S, Lazary A, Wang W, Bozsodi A, Yip S,
Bettegowda C. Prognostic significance of T gene SNP rs2305089 in individuals with spinal column
chordoma. 27th Annual Meeting of the European Musculo-Skeletal Oncology Society, Vienna, Austria
5/14 Boriani S, Lo SL, Puvanesarajah V, Fisher CG, Rhines LD, Germscheid NM, Chou D, Williams RP,
Bettegowda C, Gokaslan ZL. Aneurysmal bone cysts of the spine: treatment options and considerations.
27th Annual Meeting of the European Musculo-Skeletal Oncology Society, Vienna, Austria
5/14 Varga P, Gokaslan ZL, Sciubba DM, Wolinsky J, Bettegowda C, Luzzati A, Rhines L, Fisher C, Dekutoski
M, Boriani S. Mobile spine chordoma. Results of 168 patients from the AOSpine Primary Tumor Knowledge
Forum. 27th Annual Meeting of the European Musculo-Skeletal Oncology Society, Vienna, Austria
10/14 Varga PP, Fisher CG, Rhines LD, Boriani S, Lazary A, Wang W-L, Germscheid N, Yip S, Bettegowda C.
Prognostic significance of T gene SNP rs2305089 in individuals with spinal column chordoma. EuroSpine
2014, Lyon, France
10/14 Boriani S, Lo SL, Puvanesarajah V, Chou D, Fisher CG, Rhines LD, Williams R, Varga PP, Szoverfi Z,
Bettegowda C. Aneurysmal bone cysts of the spine: treatment options and considerations. EuroSpine 2014,
Lyon, France
3/15 Williams R, Sowman B, Boriani S, Varga PP, Luzzati A, Gokaslan ZL, Fehlings MG, Fisher CG, Dekutoski
MB, Rhines LD, Reynolds J, Bettegowda C, Kawahara N, Quraishi NA. Spinal osteoid osteoma: a
multicenter retrospective cohort study comparison of results with appendicular osteoid osteoma. British
Association of Spine Surgeons (BASS) 2015, Bath, UK
5/15 Zamorano JJ, Fehlings MG, Nater A, Tetreault L, Varga P, 10.Gokaslan ZL, Boriani S, Fisher CG, Rhines
LD, Bettegowda C, Kawahara N, Chou D. Risk factors for local recurrence after surgical resection of spine
schwannomas: retrospective analysis of 169 patients from a multicenter international database. Global Spine
Congress 2015, Buenos Aires, Argentina
5/15 Goldstein CL, Varga PP, Gokaslan ZL, Boriani S, Luzzati 9.A, Rhines L, Fisher CG, Chou D, Williams RP,
Dekutoski MB, Quraishi NA, Bettegowda C, Kawahara N, Fehlings MG. Hemangiomas of the spine: results
of surgical management and prognostic variables for local recurrence and mortality in a multicenter study.
Global Spine Congress 2015, Buenos Aires, Argentina
5/15 Sciubba D, Yurter A, Derek J, Gokaslan Z, Fisher C, 7.Rhines L, Fehlings M, Fourney D, Mendel E, Laufer
I, Bettegowda C, Goodwin CR, Patel S, Rampersaud R, Reynolds J, Chou D, Weber M, Clarke M. A
systematic review of clinical outcomes and prognostic factors for patients undergoing surgery for spinal
metastases secondary to breast cancer. Global Spine Congress 2015, Buenos Aires, Argentina
5/15 Versteeg AL, Fisher CG, Boriani S, Varga PP, Dekutoski 4.MB, Luzzati A, Gokaslan ZL, Williams RP,
Reynolds JJ, Fehlings MG, Bettegowda C, Rhines LD. Chondrosarcomas of the spine: prognostic variables
27
for local recurrence and mortality in a multicenter study. Global Spine Congress 2015, Buenos Aires,
Argentina
7/15 Fisher CG, Versteeg AL, Dea N, Boriani S, Varga PP, 2.Dekutoski MB, Luzzati A, Gokaslan ZL, Williams
RP, Reynolds JJ, Fehlings MG, Bettegowda C, Rhines LD. Chondrosarcomas of the spine: prognostic
variables for local recurrence and mortality in a multicenter study. 22nd International Meeting on Advanced
Spine Techniques (IMAST), Kuala Lumpur, Malaysia
7/15 Rhines LD, Dirks MS, Boriani S, Luzzati A, Fehlings MG, 1.Fisher CG, Dekutoski MB, Williams R,
Quraishi NA, Gokaslan ZL, Bettegowda C, Germscheid N, Varga PP. Ewing's sarcoma of the spine:
survival and local control in surgically treated patients. 22nd International Meeting on Advanced Spine
Techniques (IMAST), Kuala Lumpur, Malaysia
10/18 Bettegowda C, Yip S, Jiang B, Wang WL, Clarke MJ, Lazary A, Gambarotti M, Zhang M, Sciubba DM,
Wolinsky JP, Goodwin CR, McCarthy E, Germscheid NM, Sahgal A, Gokaslan ZL, Boriani S, Varga PP, Fisher CG,
Rhines LD. Malignant primary spinal column tumors: prognostic significance of hTERT (human telomerase
reverse transcriptase) promotor region mutations C228T and C250T for overall survival. CNS Annual
Meeting - Spine and Peripheral Nerve Section, Houston, TX.
3/19 Bettegowda C, Yip S, Jiang B, Wang WL, Clarke MJ, Lazary A, Gambarotti M, Zhang M, Sciubba DM,
Wolinsky JP, Goodwin CR, McCarthy E, Germscheid NM, Sahgal A, Gokaslan ZL, Boriani S, Varga PP, Fisher CG,
Rhines LD. Malignant primary spinal column tumors: prognostic significance of hTERT (human telomerase
reverse transcriptase) promotor region mutations C228T and C250T for overall survival. Spine Summit -
35th Annual Meeting of the Section on Disorders of the Spine and Peripheral Nerves, Miami, FL. Awarded
best abstract
5/19 Bettegowda C, Yip S, Jiang B, Wang WL, Clarke MJ, Lazary A, Gambarotti M, Zhang M, Sciubba DM,
Wolinsky JP, Goodwin CR, McCarthy E, Germscheid NM, Sahgal A, Gokaslan ZL, Boriani S, Varga PP, Fisher CG,
Rhines LD. Malignant primary spinal column tumors: prognostic significance of hTERT (human telomerase
reverse transcriptase) promotor region mutations C228T and C250T for overall survival. Spine Summit -
35th Annual Meeting of the Section on Disorders of the Spine and Peripheral Nerves, Miami, FL. Awarded
best poster.