Development and exploitation of novel food for the gluten-free market.

Mauro Rossi

Institute of Food Sciences, Avellino, Italy

The Mission • to perform research in its own Institutes, • to promote innovation and competitiveness of the national industrial system, • to promote the internationalization of the national research system, • to provide technologies and solutions to emerging public and private needs, • to advice Government and other public bodies, • to contribute to the qualification of human resources.

CNR and EU CNR’s participation in the Seventh Framework Program (2007-2013): 663 granted projects (118 CNR coordination): COOPERATION (436), CAPACITIES (97) PEOPLE (102) IDEAS (24).

Institute of Food Sciences

Celiac Disease

Normal Jejunum

Virginia Commonwealth Univ, Richmond, Virginia Celiac Disease (Gluten-Induced Enteropathy) 65000-45800-F2923

Celiac

Alternatives to classical GFD

GFD related problems: poor compliance

gluten contamination

Current therapy: GFD

Gianfrani et al, Gastroenterology ’07;133:780

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mTG

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+3 K-C2H5

mTG

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Enzyme reactor

centrifuge

Transamidated wheat flour

A

B

Enzyme treatment of wheat flourGluten cross-linking (transamidation)

gluten peptide

gluten peptide

Type of consortia and cooperation approaches

Type of consortia and cooperation approaches

New EU application: still an Innovation Action

FAST TRACK TO INNOVATION PILOT H2020-FTIPilot-2015-1 Opening Date 06-01-2015 Deadline Date 01-12-2015 17:00:00 Budget €100,000,000 Main Pillar Industrial Leadership

• the Fast Track to Innovation (FTI) pilot is testing a new approach to give the development of innovations the last push needed before their introduction to the market.

• It is the only fully bottom-up measure in Horizon 2020 promoting close-to-market innovation activities and open to all types of participants.

• The FTI pilot aims to reduce the time from idea to market and to increase the participation in Horizon 2020 of industry, SMEs and first-time industry applicants.

• FTI projects must be business-driven and clearly demonstrate a realistic potential for quick deployment and market take-up of innovations.

Type of consortia and cooperation approaches

2007 2009 2012 2014 2015 Industrial production

pilot scale

industrial scale

Industry involvement in R&D: The roadmap

start collaboration

Pathway to market

2014 2015 2016 Market

industrial scale

Commercial production

Regulatory issues Enzyme supply

DEFINITIONS • Novel food: food ingredients that have not been used for human

consumption to a significant degree in the EU before 15 May 1997. • Under the Novel Foods Regulation such foods are then subject to a

pre-market safety assessment before a decision is made on EU-wide authorisation.

• Gluten free food: <20ppm (EU and FDA Regulations)

Importance of standards and regulations

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Spin-off

Accomplished

Next Phase - Investment

Entering The Market

IPR management

accomplished

New IPR

The management of all IPR will be regulated in detail through the “Consortium Agreement (CA)” which preparation will be fully developed before the start of the project. The CA will be based on the DESCA model updated for H2020 and the current agreements already signed by some of the project partners. This agreement will also regulate the process of obtaining IP-protection, exploitation and revenue sharing between partners for foreground IP generated through the GLUTEN-DETOX project. The project will follow European Commission’s guidelines for IP and will keep up-to-date with national and European recommendations on IP management

Dissemination strategy

Important project management and governance

Important project management and governance

This project was supported by grants from ‘misura 124’’