Dilution Ptc

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  • 7/31/2019 Dilution Ptc.

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    Dobutamine

    No DRUG NAME

    (GENERIC/ TRADE

    NAME)

    PREPARATION STORAGE &

    STABILITY

    1 Dobutamine 250mg/20ml Dilution:

    Must be further diluted in IV

    container to at least a 50ml

    solution with D51/2NS,D5NS, D10, Isolyte M with

    D5, Lactated Ringer, NS or

    sodium lactate.

    Infusion rate:

    Usual effective initial dose

    ranges from to 2.5-15

    mcg/kg/min.

    On rare occasions, infusion

    rates up to 40mcg/kg/min

    have been required to obtain

    the desired effect.

    Intravenous

    solutions should

    be used within 24

    hours. Store at 20to 25 C.

    2 Dopamine 200mg/5ml Dilution:

    Must be diluted before

    administration.

    Dilute 200mg IV Dopamine

    to either 250ml NS or D5%

    (to get dopamine

    concentration of 800mcg/ml)

    or 500ml NS orD5% (to getdopamine concentration of

    400mcg/ml)

    After dilution,

    stable for at least

    24 hr.

    3 Ertapenem Must be reconstituted and thendiluted prior to administration

    Patient 13 years of age and

    older

    IV:

    1. Reconstitute thecontents of a 1g vial of

    ertapenem with 10ml

    of on of the following:

    Water for Injection,

    0.9% Sodium Chloride

    Injection or

    Bacteriostatic Water

    for Injection.

    2. Shake well to dissolve

    and immediatelytransfer contents of the

    reconstituted vial to

    50ml of 0.9% Sodium

    Chloride Injection.

    IV:

    Complete the

    infusion within 6

    hours of

    reconstitution.

    IM:

    The reconstitutedIM solution

    should be used

    within 1 hour after

    preparation. Note:

    The reconstituted

    solution should

    be not be

    administered

    intravenously.

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    IM:

    1. Reconstitute thecontents of a 1g vial of

    ertapenem with 3.2ml

    of 1.0% or 2.0%

    lidocaine HCl injection

    (without

    epinephrine). Shake

    vial thoroughly to form

    solution.

    2. Immediately withdraw

    the contents of the vial

    and administer by deep

    intramuscular injection

    into a large muscle

    mass (such as the

    gluteal muscles or

    lateral part of thethigh).

    Pediatric patients 3 months

    to 12 years of age

    IV:

    1. Reconstitute the

    contents of a 1g vial of

    ertapenem with 10ml

    of on of the following:Water for Injection,

    0.9% Sodium Chloride

    Injection or

    Bacteriostatic Water

    for Injection.

    2. Shake well to dissolve

    and immediately

    withdraw a volume

    equal to 15mg/kg of

    body weight (not

    exceed 1g/day) anddilute in 0.9% Sodium

    Chloride Injection to a

    final concentration of

    20mg/ml or less.

    IM:

    1. Reconstitute thecontents of a 1g vial of

    ertapenem with 3.2ml

    of 1.0% or 2.0%lidocaine HCl injection

    (without

    epinephrine). Shake

    vial thoroughly to form

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    solution.

    2. Immediately withdrawa volume equal to

    15mg/kg of body

    weight (not exceed

    1g/day) and administer

    by deep intramuscular

    injection into a large

    muscle mass (such as

    the gluteal muscles or

    lateral part of the

    thigh).

    4 Erythromycin

    5 Frusemide 20mg/2ml Dilute:

    2ml amp to 50ml NS/D5

    IV/IVB/IM:

    Up to 4mg/ml

    1D (RT)

    6

    Fluconazole 2mg/ml Usual Diluents: NS

    Standard dilutions

    [Amount of drug] [Infusion

    volume] [Infusion rate]:

    (ready-to-use)

    [200mg] [100ml] [1hour]

    [400mg] [200ml] [2hours]

    EXP: Some

    studies indicate 7

    DAYS (RT) if

    solution is

    transferred.

    Label: Do not

    Refrigerate.

    Maximum IVrate: 200mg/hr.

    IV: since oral

    absorption is

    rapid and

    essentially

    complete, IV

    dose = oral dose