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7/31/2019 Dilution Ptc.
1/3
Dobutamine
No DRUG NAME
(GENERIC/ TRADE
NAME)
PREPARATION STORAGE &
STABILITY
1 Dobutamine 250mg/20ml Dilution:
Must be further diluted in IV
container to at least a 50ml
solution with D51/2NS,D5NS, D10, Isolyte M with
D5, Lactated Ringer, NS or
sodium lactate.
Infusion rate:
Usual effective initial dose
ranges from to 2.5-15
mcg/kg/min.
On rare occasions, infusion
rates up to 40mcg/kg/min
have been required to obtain
the desired effect.
Intravenous
solutions should
be used within 24
hours. Store at 20to 25 C.
2 Dopamine 200mg/5ml Dilution:
Must be diluted before
administration.
Dilute 200mg IV Dopamine
to either 250ml NS or D5%
(to get dopamine
concentration of 800mcg/ml)
or 500ml NS orD5% (to getdopamine concentration of
400mcg/ml)
After dilution,
stable for at least
24 hr.
3 Ertapenem Must be reconstituted and thendiluted prior to administration
Patient 13 years of age and
older
IV:
1. Reconstitute thecontents of a 1g vial of
ertapenem with 10ml
of on of the following:
Water for Injection,
0.9% Sodium Chloride
Injection or
Bacteriostatic Water
for Injection.
2. Shake well to dissolve
and immediatelytransfer contents of the
reconstituted vial to
50ml of 0.9% Sodium
Chloride Injection.
IV:
Complete the
infusion within 6
hours of
reconstitution.
IM:
The reconstitutedIM solution
should be used
within 1 hour after
preparation. Note:
The reconstituted
solution should
be not be
administered
intravenously.
7/31/2019 Dilution Ptc.
2/3
IM:
1. Reconstitute thecontents of a 1g vial of
ertapenem with 3.2ml
of 1.0% or 2.0%
lidocaine HCl injection
(without
epinephrine). Shake
vial thoroughly to form
solution.
2. Immediately withdraw
the contents of the vial
and administer by deep
intramuscular injection
into a large muscle
mass (such as the
gluteal muscles or
lateral part of thethigh).
Pediatric patients 3 months
to 12 years of age
IV:
1. Reconstitute the
contents of a 1g vial of
ertapenem with 10ml
of on of the following:Water for Injection,
0.9% Sodium Chloride
Injection or
Bacteriostatic Water
for Injection.
2. Shake well to dissolve
and immediately
withdraw a volume
equal to 15mg/kg of
body weight (not
exceed 1g/day) anddilute in 0.9% Sodium
Chloride Injection to a
final concentration of
20mg/ml or less.
IM:
1. Reconstitute thecontents of a 1g vial of
ertapenem with 3.2ml
of 1.0% or 2.0%lidocaine HCl injection
(without
epinephrine). Shake
vial thoroughly to form
7/31/2019 Dilution Ptc.
3/3
solution.
2. Immediately withdrawa volume equal to
15mg/kg of body
weight (not exceed
1g/day) and administer
by deep intramuscular
injection into a large
muscle mass (such as
the gluteal muscles or
lateral part of the
thigh).
4 Erythromycin
5 Frusemide 20mg/2ml Dilute:
2ml amp to 50ml NS/D5
IV/IVB/IM:
Up to 4mg/ml
1D (RT)
6
Fluconazole 2mg/ml Usual Diluents: NS
Standard dilutions
[Amount of drug] [Infusion
volume] [Infusion rate]:
(ready-to-use)
[200mg] [100ml] [1hour]
[400mg] [200ml] [2hours]
EXP: Some
studies indicate 7
DAYS (RT) if
solution is
transferred.
Label: Do not
Refrigerate.
Maximum IVrate: 200mg/hr.
IV: since oral
absorption is
rapid and
essentially
complete, IV
dose = oral dose