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Direcția Politici și Programe Europene și Internationale
JPIAMR 3rd Joint Call: JPI-EC-AMR ERA-NET Cofund Call on Transmission Dynamics
Who we are?
General information Name of organisation:Research-Development Institute for Plant Protection Adress Blvd. Ion Ionescu de la Brad nr. 8, CP 013813, OP 18, Bucureşti - ROMANIA Phone 004-021-2693231 (32, 34) Fax 004-021-2693239 E-mail [email protected] Type of organisation: research Contact person Name: Fendrihan Sergiu Country: Romania Address: Blvd. Ion Ionescu de la Brad nr. 8, CP 013813, OP 18, Bucureşti - ROMANIA Tel: 004-021-2693231 (32, 34); mobile 004-0720134916 Fax: 004-021-2693239 E-mail: [email protected] General description of the project proposed/activity Bioscreening / bioprospecting of endophitic and rhizosphere microorganisms of cultivated plant for new antibiotics and new antifungals in order to overcome the resistance of human pathogens. Interest for the topic: ½ Project idea: Endophitic microorganisms are microorganism which has as habitat differents plants organs being not pathogens or symbionts.There fungi, bacteria, actynomicetes. From plants of agricultural interest, were isolated a lot of bacteria and fiungi antagonists of plants and not only pathogens. They both are releasing substances with antibiotic/antifungi properties which could be a base for new antifungals / antibiotics in the situation of increasing pathogens resistance to classical antibiotics / antifungals, Strains with such potential are form the genera Bacillus, Paenibacillus, Steptomyces, Kokuria, Micrococcus Acetobacter, Klebsiella Rhizobium, and so on, Many of these strains release substances with pharmaceutical potential (antibiotics, antifungal, antitumoral), have in the same time, an effect of stimulation of plants growth and development. The Res Instit,. for Plant Protection has a work groups regarding bacteriology of plants and soils, having a collection of strains with the necessary properties. Relevant publications: 1.Fendrihan S.,(2013) Preliminary result of isolation of bacteria fom potato tubers.RJPP, nr,2 vol XV 2.Fendrihan S. (2014) Bacteria and modern agriculture RJPP, vol XVI
Direcția Politici și Programe Europene și Internationale 3.Kefi A, Slimene IB, Karkouch I, Rihouey C, Azaeiz S, Bejaoui M, Belaid R, Cosette P, Jouenne T, Limam F. Characterization of endophytic Bacillus strains from tomato plants (Lycopersicon esculentum) displaying antifungal activity against Botrytis cinerea Pers. World J Microbiol Biotechnol. 2015 Sep 7. [Epub ahead of print] 4.Maachia B, Rafik E, Chérif M, Nandal P, Mohapatra T, Bernard P. Biological control of the grapevine diseases 'grey mold' and 'powdery mildew' by Bacillus B27 and B29 strains. Indian J Exp Biol. 2015 Feb;53(2):109-15. 5.Kumar Pandey, Siddhartha Singh, Raj Naraian Singh Yadav, Amit Kumar Singh, M. Chandra Kumar Sing Fungal Endophytes: Promising Tools for Pharmaceutical Scienct Int. J. Pharm. Sci. Rev. Res., 25(2), Mar – Apr 2014; Article No. 25, Pages: 128-138 ISSN 0976 – 044X 6.Sutjaritvorakul, T., Whalley, A.J.S., Sihanonth, P. and Roengsumran, S. Antimicrobial activity from endophytic fungi isolated from plant leaves in Dipterocarpous forest at Viengsa district Nan province, ThailandJournal of Agricultural Technology 2011 Vol. 7(1): 115-121 7Jitendra Dalal and Nikhilesh Kulkarni Antagonistic and Plant Growth Promoting Potentials of Indigenous Endophytic Bacteria of Soybean (Glycine max (L) Merril) Current Research in Microbiology and Biotechnology Vol. 1, No. 2 (2013): 62-69 Type of partner search: university, research institution, pharma company with research dept, and so on RELEVANT CALL: Joint call 3
th Call 2016
Topics To understand the acquisition, persistence/ retention, and transmission of resistant organisms and resistance genes, research should investigate:
Selection of resistance and its transmission between individuals and between human and non-human sources
The success of clones, organisms, and resistance patterns and the role of different genetic elements.
The fitness of the resistant bacteria in clinical, community, veterinary, and environmental settings. Other: Publication date: January 18th, 2016 (17:00, CET) Closing date (deadline for preproposal): March 21th, 2016 What we are looking for ? Partner sought Country : England , France, Germany, Austria, Bulgaria, Hungary Expertise requested: pharmacy microbiology, antibiotics testing and production, clinical trials Role partners Organisation type: university, research institution, company, hospital How many partners are required? 3
