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DNAAbbreviation- Deoxyribonucleic Acid
James Watson & Francis Crick-in 1953 discovered DNA was 2 strands and twisted
Double Helix- 2 word term to describe DNA
Codon---3 base sequence---ATA
Rules for base pairing for DNA
•Thymine to Adenine•Adenine to Thymine•Cytosine to Guanine•Guanine to Cytosine
Complementary strand DNA to DNA
• A T G A T C G T G C A
• T A C T A G C A C G T
PartsSugar
ADENINE
THYMINE
CYTOSINE
GUANINEGUANINEPHOSPHATEPHOSPHATE
DNA Replication
DNA Helicase- enzyme that unzips DNA for replication
DNA Polymerase- enzyme that completes DNA replication
Occurs- Synthesis or S stage of Interphase
End Result- Sister Chromatids
Replication
• A T
• T A
• C G
• G C
• T A
• C G
• OLD• A T old A T old• T A T A• C G C G• G C G C• T A T A• C G C G
New New• A T old A T AT old• T A T A TA• C G CG CG• G C GC GC• T A TA TA• C G CG CG
RNA• RNA- Ribonucleic Acid
• Codon---three base sequence of mRNA UGU
• Transcription- making of mRNA from DNA
• RNA polymerase- enzyme that unzips DNA for transcription.
• Ribose- the sugar in RNA
Base Pairing Rules for RNA to DNA
DNA mRNAThymine Adenine Adenine URACILCytosine Guanine Guanine Cytosine
DNA to mRNA
• A T G A T C G T G C A
• U A C U A G C A C G U
How mRNA and tRNA work together?1. An mRNA codon pairs up with a tRNA
anticodon.
2. tRNA anticodons bring with it an amino acid.
3. The amino acid it brings is based on the code in mRNA.
4. The mRNA and tRNA release from each other.
5. All that is left in the ribosome is a strand of AMINO ACIDS
6. ALSO KNOWN AS a PROTEIN
Four DifferencesDNA RNA
1. Sugar Deoxyribose Ribose
2. Strand 2 stranded 1 strand
3. Stored Nucleus Nucleolus
4. Bases Thymine Uracil
Adenine Adenine
Protein Synthesis
Protein Sythesis-Translation
Takes Place-- Ribosome
Protein- long strand of amino acids
Anticodon- three base sequence tRNA
EXTRA INFO
Three parts of a nucleotide
1.Phosphate
2.Sugar-----Deoxyribose(DNA) or Ribose(RNA)
3.Nitrogen base
Where do the bases pair up on DNA?
At the sugars
Protein Synthesis Using mRNA CODONS and tRNA Anticodons
Remember to
LOOK UP THE CODON on the chart
not the
ANTICODON
Ex GGG anticodon
CCC CODON
Amino Acid :
PROLINE (CCC)