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Don’t wait for them to tell you. I have worms

Don’t wait for them to tell you

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Don’t wait for them to tell you.

I have worms

Unlike other products, the active ingredients in Drontal® work synergistically to kill roundworms and hookworms11.

# Including immature T. canis. ^Aids in control of U. stenocephala only. *T. pisiformis only.

NO

SYN

ER

GY

DR

ON

TAL®

Three powerful active ingredients combine to control gastrointestinal worms and Giardia spp. cysts. Drontal® is scientifically proven to kill more gastrointestinal worms1-10.

Roundworms Hookworms Tapeworms Whipworm Protozoa

ActiveIngredients Product/s

T. ca

nis

T. le

onin

a

A. c

anin

um

A. b

razi

liens

e

A. c

eyla

nicu

m

U. s

teno

ceph

ala

D. c

anin

um

Taen

ia s

pp.

E. g

ranu

losu

s

T. v

ulpi

s

Giar

dia

FebantelPyrantel

PraziquantelDrontal® 3 3 3 3 3 3 3 3 3 3 3

PyrantelOxantel

Praziquantel

Canex®

Popantel®

Exelpet ®3 3 3 3 3 3 3 3 3 3

Milbemycin oxime

Praziquantel

Milbemax® 3 3 3 3 3 3 3 3

Interceptor® 3# 3 3 3 ^ 3 * 3 3

OxibendazolePraziquantel

Endogard® Paragard® 3 3 3 3 3 3 3 3

IvermectinPyrantel

Heartgard 30 Plus® 3 3 3 3 3 3

Fenbendazole Panacur® for Dogs 3 3 3 3 3 3

ACTIVE INGREDIENT

TARGET WORM

CHEMICALGROUP

MODE OF ACTION(against worms)

Pyrantel RoundwormHookworm Pyrimidine Paralysis

FebantelRoundwormHookwormWhipworm

Pro- benzimidazole Starvation

‘LOOK-ALIKE’ WORMERS

ACTIVE INGREDIENT TARGET WORM CHEMICAL

GROUP

Pyrantel RoundwormHookworm Pyrimidine

Oxantel Whipworm Pyrimidine

What does synergy actually mean for worm control? The combined effect of pyrantel and febantel on hookworms and roundworms is greater than the sum of their individual effects on these worms. This powerful, double-barrelled approach minimises the chance of less susceptible worms surviving treatment compared to single active or non-synergistic wormers.

Drontal®– the established allwormer developed in Australia,

and trusted worldwide by pet owners.

Watch out!

Not all wormers kill every

hookworm species. Drontal® is highly effective against

all 4 species. Adapted from Palmer CS et al. 2007 and Taveros AA, 199012,13.

This worm attaches to the wall of the human intestine, feeds on blood and produces eggs. It causes abdominal pain, diarrhoea

and anaemia. Most wormers don’t control this parasite.

Ancylostoma ceylanicum is an emerging public health risk18!

Ancylostoma ceylanicum was found in >10% of

hookworm-positive dogs in Australia12.

RESULTSWithin 3 days of treatment, no

eggs were detected in the faeces of Drontal®-treated dogs.

Drontal® has 100% efficacy

against A. ceylanicum19.

Days post infection

TREATMENT

Mea

n eg

gs/g

faec

es

3530252015

0

4000

6000

8000

10000

12000

2000

Control

Treatment

U. stenocephala

A. caninumA. ceylanicum

A. brazilienseHookworm

infestations were found in 10%-17%

of dogs in Australian shelters, >17% of

farm dogs from NSW, >40% of farm dogs from Tasmania and 5% of rural dogs in

Victoria14,15.

Comparative mean efficacy of a single dose of common intestinal wormers against natural infestations of A. caninum16.

Source: Hopkins T.J. et al. 1998. Aust Vet Pract. 28(2):53 56

Efficacy %

63%

76%

85%

74%

99%

10020 40 60 800

Drontal®

Pyrantel / oxantel as in Canex M.S.®

Pyrantel / oxantel as in Canex Cube®

Pyrantel / oxantel as in Popantel®

Milbemycin oxime as in Interceptor®, Sentinel® and Milbemax®

Efficacy of oxibendazole

has been shown to be

as low as 8%17.

Look-alike wormer

Look-alike wormer

Look-alike wormer

Drontal® effectively kills both roundworm species found in Australian dogs –

Toxocara canis and Toxascaris leonina.

In high-risk areas for whipworm, dogs should be treated every 6-8 weeks with Drontal® - check with your vet.

Whipworms have been found in 13% of Australian mainland dogs, with even higher rates in farm dogs from Tasmania and NSW15.

Drontal® is 95% effective

against whipworm infestations20.

Whipworm eggs can survive in the environment for years. Keep dogs protected with Drontal®.

Comparative mean efficacy of worming products against Toxocara canis20.

Efficacy %

79%

75%

98%

10020 40 60 800

Drontal®

Pyrantel embonate

Pyrantel embonate plus oxantel

embonate tablet Look-alike wormer

TAPEWORM DRONTAL® DOSING REGIME

Hydatid and sheep measles tapeworms Every 6 weeks

Taeniid (excl. Sheep Measles) Every 3 months

Flea Every 3 months

Drontal® Allwormer is a broad spectrum wormer that safely and effectively removes 100% of tapeworms, including the hydatid tapeworm.

Reducing the exposure of dogs to tapeworms is important to reduce the zoonotic risk to human health. Dogs should:

• Be dewormed regularly

• Receive regular flea treatments

• NOT be fed/allowed to feed on raw offal or carcassesHydatid tapeworm

(Echinococcus granulosus).

Roundworms (T. canis) inside a dog’s small intestine (cut open).

Dogs with intestinal parasite infections are often asymptomatic, meaning they can be contaminating their environment, and putting other animals and humans at risk! Drontal® reduces the risk of zoonotic infections by killing all the important worms and reducing egg shedding by dogs.

Zoonotic Potential Most people are unaware that they can become infected

with intestinal parasites found in dogs!

Following ingestion of eggs, larvae hatch

then migrate throughout the body,

causing organ damage (e.g. blindness,

respiratory failure).

ROUNDWORMThe most important species, the hydatid

tapeworm, forms cysts in various organs, causing

damage and dysfunction. Can be fatal.

TAPEWORMFollowing ingestion

of cysts, humans develop watery

diarrhoea, abdominal cramps,

vomiting, dehydration and

weight loss.

GIARDIALarvae penetrate and migrate through the skin causing itchy migration tracts. Two species reach the intestines following ingestion or larval penetration,

one causing intestinal inflammation and the other

maturing and laying eggs.

HOOKWORM

*Treatment should only commence following diagnosis by a veterinarian.

Drontal® Allwormer is proven to reduce Giardia spp. cyst shedding in dogs when given on 3 consecutive days at the normal dose21.

Treatment

Days

Cys

ts/g

(log

10)

-3 -1 1 2 3 5 7 90-5-7

0

1

2

3

4

5

6

Control dogsTreated dogs

Roundworm visceral larva migrans in a human eye

Giardia spp. is the most prevalent gastrointestinal parasite in Australian dogs14.

Not only is it TRUSTED and PROVEN to kill all 12 gastrointestinal worms found in Australian dogs, it is the only registered allwormer to control

Giardia spp., providing a simple and affordable solution.

PRODUCT ACTIVE INGREDIENTS FORMULATION SIZES

Drontal® Allwormer Chewable for Dogs

PyrantelFebantel

Praziquantel

Chewable 1 chew / 10 kg1 chew / 35 kg

Drontal® Allwormer Tablets for Dogs Tablet

1 tablet / 3 kg1 tablet / 10 kg1 tablet / 53 kg

Drontal® Suspension for Puppies

PyrantelFebantel Liquid 1 ml / kg

The Drontal® range is suitable for dogs of all shapes and sizes.

Dogs think Drontal® chews are super tasty, we checked17!

Combining the unique and highly effective ingredients of the tablets with a delicious liver flavoured chew making treating

dogs for intestinal worms easy!

Ingredients evenly distributed through chews so they can be split.

Chews are still effective even if swallowed whole, unlike other wormers.

of dogs readily accepted Drontal® Chews within the observation period98% Benefits

Stress-free treatment for owners and their dogs.

Peace of mind for owners that their dog has been wormed.

Easy to get into a regular Drontal® worming program.

% of Acceptance

Drontal® Chew 98%

It is also suitable for dogs at every stage of their life providing stress free control

of gastrointestinal parasites.

Safe to use in puppies

from 2 weeks of age.

Available as chews, tablets

or a puppy suspension.̂

Safe to use during

pregnancy and lactation.*

No minimum weight.

Safe in combination with

other parasite products and medications.

*See label for full details. ^Does not contain praziquantel. References: 1. Drontal Registered Product Label. 2. Canex Cube Registered Product Label. 3. Popantel Registered Product Label. 4. Exelpet Intestinal Allwormer Tablets/Chews Registered Product Label. 5. Milbemax Registered Product Label. 6. Interceptor Registered Product Label. 7. Endogard Registered Product Label. 8. Paragard Registered Product Label. 9. Heartgard 30 Plus Registered Product Label. 10. Panacur for Dogs Registered Product Label. 11. Mehlhorn H et al. Parasitol Res 2003; 90:305-313. 12. Palmer CS et al. Vet Parasitol 2007;145(3-4):304-313. 13. Taveros AA. Survey of the prevalence and intensity of Dirofilaria immitis and gastrointestinal helminths of pound dogs in Townsville, North Queensland. M.Sc., James Cook University, 1990. 14. Palmer CS et al. Vet Parasitol 2008; 151:181-190. 15. Jenkins DJ et al. Aust Vet J 2014; 92(8):292-298. 16. Hopkins TJ et al. Aust Vet Practit 1998; 28(2):53-56. 17. Bayer Data on File. 18. Smout FA et al. One Health 2017; 3:66-69. 19. Taweethavonsawat P et al. Parasitol Res 2010; 106:533-537. 20. Hopkins TJ et al. Vet Med Rev 1987. 21. Bowman DD et al. Parasitol Res 2009; 105:S125-S134. 22. Agricultural and Veterinary Chemicals Code Regulations 1995. Canex® is a registered trademark of Zoetis. Popantel® is a registered trademark of Jurax. Exelpet® is a registered trademark of Mars. Milbemax® and Interceptor® is a registered trademark of Elanco. Endogard® is a registered trademark of Virbac. Paragard is® a registered trademark of Merial. Heartgard® is a registered trademark of Boehringer Ingelheim. Panacur® is a registered trademark of Merck. Drontal® is a registered trademark of Vetoquinol. Customer Care Line 1800 032 355 toll free from anywhere in Australia.

VETOQUINOL AUSTRALIA PTY LTDUnit 302/2, 6-12 Boronia RoadDa Vinci Business ParkBrisbane Airport QLD 4008www.vetoquinol.com.au

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4/21

Drontal® has been trusted in Australia for over 30 years and is the

safe and effective choice for protecting your pet and family.