Dosage and Solutions_Final

Dosage and SolutionsDosage and Solutions

Gerardo I. Lirag, RNGerardo I. Lirag, RN

Lung Center of the PhilippinesLung Center of the Philippines

I.V. Therapy Training Program for NursesI.V. Therapy Training Program for Nurses

Commonly Used UnitsCommonly Used Units

cc (cubic centimeter) or (cmcc (cubic centimeter) or (cm33) centimeter ) centimeter cubecube

ml (milliliter) ml (milliliter) mg (milligram)mg (milligram) ų (micro) ų (micro) g (gram)g (gram) qtts (drops) qtts (drops) kg (kilogram)kg (kilogram) G (gauge) G (gauge) meq (milli-equivalent) meq (milli-equivalent) u (unit)u (unit)

1 ml = 1 cc1 ml = 1 cc 1 liter = 1000 ml1 liter = 1000 ml 1 kg = 1000 g1 kg = 1000 g 1 g = 1000 mg1 g = 1000 mg 1 mg = 1000 ųg1 mg = 1000 ųg 1 hr. = 60 min.1 hr. = 60 min. 1 min. = 60 sec. 1 min. = 60 sec. 1 ųqtts/min = 1 ml/hr1 ųqtts/min = 1 ml/hr

Review of ConversionReview of Conversion

Commonly Used Drop FactorCommonly Used Drop Factor

Macroset Abbot (15 qtts/ml)Macroset Abbot (15 qtts/ml)

BlBraun (20 qtts/ml)BlBraun (20 qtts/ml) BT Set Abbot (10 qtts/ml)BT Set Abbot (10 qtts/ml)

Microset (60 qtts/ml)Microset (60 qtts/ml)

Commonly Used Emergency Drugs Commonly Used Emergency Drugs and its Stocksand its Stocks

Epinephrine 1mg/mlEpinephrine 1mg/ml Atropine Sulfate 1 mg/mlAtropine Sulfate 1 mg/ml Aminophylline 25mg/ml in 10 mlAminophylline 25mg/ml in 10 ml Paracetamol (Aeknil) 150mg/ml in 2mlParacetamol (Aeknil) 150mg/ml in 2ml Diphenhydramine HCL (Benadryl) 50mg/ml in 1mlDiphenhydramine HCL (Benadryl) 50mg/ml in 1ml Hyoscine Butylbromide (Buscopan) 20mg/1mlHyoscine Butylbromide (Buscopan) 20mg/1ml Terbutaline Sulfate (Bricanyl) 500ųg/ml in 1mlTerbutaline Sulfate (Bricanyl) 500ųg/ml in 1ml

Isosorbide dinitrate (Isoket) 1mg/ml in 10mlIsosorbide dinitrate (Isoket) 1mg/ml in 10ml Tranexamic Acid (Hemostan) 100mg/ml in 5mlTranexamic Acid (Hemostan) 100mg/ml in 5ml Diazepam (Valium) 5mg/ml in 2mlDiazepam (Valium) 5mg/ml in 2ml Phenytoin Na (Dilantin) 50mg/ml in 2mlPhenytoin Na (Dilantin) 50mg/ml in 2ml Dopamine 40mg/ml in 5mlDopamine 40mg/ml in 5ml Dobutamine 50mg/ml in 5mlDobutamine 50mg/ml in 5ml Furosemide (Lasix) 10mg/ml in 2mlFurosemide (Lasix) 10mg/ml in 2ml

Verapamil (Isoptin) 5mg/2mlVerapamil (Isoptin) 5mg/2ml Digoxin (Lanoxin) 0.5 mg/2mlDigoxin (Lanoxin) 0.5 mg/2ml Magnesium Sulfate 250mg/ml in 10mlMagnesium Sulfate 250mg/ml in 10ml Metoclopramide (Plasil) 5mg/2mlMetoclopramide (Plasil) 5mg/2ml Ranitidine (Zantac) 25mg/mlRanitidine (Zantac) 25mg/ml Phytomenadione (Hema-K) 10mg/ml in 1mlPhytomenadione (Hema-K) 10mg/ml in 1ml Nalbuphine (Nubain) 10mg/ml in 1mlNalbuphine (Nubain) 10mg/ml in 1ml

Tramadol (Tramal) 50mg/ml in 1mlTramadol (Tramal) 50mg/ml in 1ml Midazolam (Dormicum) available in Midazolam (Dormicum) available in

5mg/5ml, 15mg/3ml, 5mg/1ml5mg/5ml, 15mg/3ml, 5mg/1ml Dexamethasone 4mg/ml in 2mlDexamethasone 4mg/ml in 2ml Sodium bicarbonate 1meq/ml in 50mlSodium bicarbonate 1meq/ml in 50ml Hydrocortisone (Solu Cortef) 100mgHydrocortisone (Solu Cortef) 100mg Lidocaine (Xylocaine 2%) 20mg/ml in 5mlLidocaine (Xylocaine 2%) 20mg/ml in 5ml

FormulaFormula

D = dose desired (in mg)D = dose desired (in mg)

H = Dose on Hand (total dose in mg)H = Dose on Hand (total dose in mg)

Q = Quantity (total volume in ml)Q = Quantity (total volume in ml)

R = Required or amount to be administeredR = Required or amount to be administered

R =(Q)(D)

H

FormulaFormula

R = Rate in qtts/minR = Rate in qtts/min

V = Volume in ml or ccV = Volume in ml or cc

DF = Drop Factor in qtts/mlDF = Drop Factor in qtts/ml

T = Time in minutesT = Time in minutes

R =(V)(DF)

T

FormulaFormula

R = Rate to be administeredR = Rate to be administered

D = Desired dose in mg/hrD = Desired dose in mg/hr

S = Total solutions in mg/mlS = Total solutions in mg/ml

R =D

S

S =Solute (mg)

Solvent (ml)

FormulaFormula

Dopamine = Dopamine = [Wt[Wt(kg)(kg)] [D] [D(ųg/kg/min)(ųg/kg/min)][60][60min/hrmin/hr]]

800 ųg/ml800 ųg/ml

Dopamine = Dopamine = 1600 ųg/ml1600 ųg/ml

Single dose Single dose

Double dose Double dose

[Wt[Wt(kg)(kg)] [D] [D(ųg/kg/min)(ųg/kg/min)][60][60min/hrmin/hr]]

FormulaFormula

Dobutamine = Dobutamine = 1000 ųg/ml1000 ųg/ml

2000 ųg/ml2000 ųg/ml

Single dose Single dose

Double dose Double dose

Dobutamine = Dobutamine =



Computation of DrugsComputation of Drugs

Problem 1Problem 1

Please administer 40mg of gentamicin thru Please administer 40mg of gentamicin thru IV every 12 hours. How much volume will IV every 12 hours. How much volume will your aspirate if the stock dose of your aspirate if the stock dose of gentamicin is 80mg/2ml?gentamicin is 80mg/2ml?

Problem No. 1

Given: D = 40 mg

H = 80 mg

Q = 2 ml

R = ?

Formula: R = (D)(Q)

H

Solution: R = (40mg)(2ml)

80mg

R = 1ml

R = 80ml

80

Answer

Problem 2Problem 2

Start DStart D55NSS 1 liter using a DF of 15 and NSS 1 liter using a DF of 15 and

regulate it for 16 hours. Calculate for the regulate it for 16 hours. Calculate for the qtts/min.qtts/min.


Problem No. 2

Given:

DF = 15 qtts/ml

T = 16 hours or 960 mins

R = ?

Formula: R = (V)(DF)

T

Solution: R = (1000ml)(15qtts/ml)

960 mins

R = 16 qtts/min

R = 15000qtts

960 mins

Answer

V = 1 liter or 1000ml of D5NSS

Problem 3Problem 3

Start DStart D55NSS 500ml using a DF of 20 and NSS 500ml using a DF of 20 and

regulate at 125ml/hr. Calculate for the regulate at 125ml/hr. Calculate for the qtts/min.qtts/min.


Problem No. 3

Given: V = 125 ml

DF = 20 qtts/ml

T = 1 hour or 60 mins

R = ?

Formula: R = (V)(DF)

T

Solution: R = (125ml)(20qtts/ml)

60 mins

R = 42 qtts/min

R = 2500qtts

60 mins

Answer


Problem 4Problem 4

Please prepare diazepam drip by Please prepare diazepam drip by dissolving 30mg of diazepam in Ddissolving 30mg of diazepam in D55W 100 W 100

ml by soluset and regulate it at 5mg/hr. ml by soluset and regulate it at 5mg/hr. Calculate for the qtts/min.Calculate for the qtts/min.

Note: Always use a microset everytime we sidedrip a dopamine, Note: Always use a microset everytime we sidedrip a dopamine, dobutamine, cardiac drugs, and sedatives.dobutamine, cardiac drugs, and sedatives.

Problem No. 4

Given:

Solvent = 100 ml of D5Water

D = 5 mg/hr

R = ? in µqtts/min

Formulas: S = Solute

Solvent

Solution:

R = 17 ml/hr ≈ 17 µqtts/min

R = 5mg/hr

0.3 mg/ml

Answer

R = D

S

S = 30mg

100ml S = 0.3mg/ml

Solute = 30 mg of Diazepam


Problem 5Problem 5

Please start lidocaine drip by dissolving 5 g. Please start lidocaine drip by dissolving 5 g. of lidocaine in Dof lidocaine in D55W 500ml and regulate it at W 500ml and regulate it at

5mg/min. Calculate for the ml/hr.5mg/min. Calculate for the ml/hr.


Problem No. 5

Given:

Solvent = 500 ml of D5Water

D = 5 mg/min

R = ? in ml/hr

Formulas: S = Solute

Solvent

Solution:

R = 30 ml/hr

R = 5 mg/min

10 mg/ml

Answer

R = D

S

S = 5,000mg

500ml S = 10 mg/ml

R =

5 mg

10 mg/ml

( 1 hr

60 min 1 min )

R =

5 mg

0.01666 hr 10 mg/ml

R = 300 mg/hr

10 mg/ml

Solute = 5 grams or 5,000 mg of Lidocaine

Problem 6Problem 6

Start dopamine drip double dose in Start dopamine drip double dose in DD55W250ml, assuming weight of patient is W250ml, assuming weight of patient is

50 kg. Regulate drip at 5ųg/kg/min. 50 kg. Regulate drip at 5ųg/kg/min. Calculate for the qtts/min.Calculate for the qtts/min.



Problem No. 6

Given:

D = 5 µg/kg/min

Concentration = double dose

Formula: R = (Wtkg)(D)(60)

1,600 µg/ml

Solution: R = (50 kg)(5 µg/kg/min)(60min/hr)

1,600 µg/ml


R = 15,000kg- µg/kg/min-min/hr

1,600 µg/ml

Answer

R = ?

Wtkg = 50 kg

Problem 7Problem 7

Start dobutamine drip double dose in Start dobutamine drip double dose in DD55W250ml, assuming weight of patient is W250ml, assuming weight of patient is

55 kg. Regulate drip at 5ųg/kg/min. 55 kg. Regulate drip at 5ųg/kg/min. Calculate for the qtts/min.Calculate for the qtts/min.



Problem No. 7

Given:

D = 5 µg/kg/min

Concentration = double dose

Formula: R = (Wtkg)(D)(60)

2,000 µg/ml

Solution: R = (55 kg)(5 µg/kg/min)(60min/hr)

2,000 µg/ml


R = 16,500kg- µg/kg/min-min/hr

2,000 µg/ml

Answer

R = ?

Wtkg = 55 kg

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Dosage and Solutions_Final