March 1 - 2, 2013BOLOGNA - ItALy

Electrochemotherapy2nd International Users’ Meeting

Come, Share, Learn

Royal Carlton HotelVia Montebello, 8 - Bologna - ItALy

CLINIPORATORLEADING CLINICAL ELECTROPORATION

Friday, March 1

8:15 - 8:35WelcoMe Manzoli FA - Istituto Ortopedico Rizzoli, Bologna, ItalyBaldi G - Istituto Ortopedico Rizzoli, Bologna, Italy

Electrochemotherapy 2nd International Users’ MeetingCadossi R - IGEA, Carpi, Italy

Electroporation, electrochemotherapy, and their perspectivesMir LM - Centre National de la Recherche Scientifique,Institut Gustave Roussy, Paris, France

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8:35 - 9:35results oF electrocheMotherapy FolloWing esope standard operating procedures Moderators: Testori A, Odili J

Five years with INSPECT, progress and perspectivesGehl J - Copenhagen University Hospital, Herlev, Denmark

First report on IMI-GIDO registry for ECT in ItalyDe Salvo G - Istituto Oncologico Veneto - IRCCS, Padua, Italy

Anti-tumour effectiveness of electrochemotherapy: a systematic review and meta-analysisMali B, Jarm T, Snoj M, Sersa G, Miklavčič D - University of Ljubljana, Ljubljana, Slovenia

Systemic chemotherapy and electrochemotherapy in breast cancer patientsMarchetti P - Azienda Ospedaliera S. Andrea, Rome, Italy

Discussion

9:35 - 10:35Multidisciplinary experiences in a cancer centre Moderators: Petrella G, Ulrich J

Use and exploration of ECT at the National Cancer Institute of NaplesMozzillo N - Istituto Nazionale Tumori - Fondazione Pascale, Naples, Italy

Center for Experimental Drug and Gene Electrotransfer: Updating indications, electrodes and drugs in electrochemotherapy and gene therapyGehl J - Copenhagen University Hospital, Herlev, Denmark

Relevance of ECT in one of the largest melanoma centres of GermanySchulze HJ - Fachklinik Münster-Hornheide, Germany

A review of bleomycin lung toxicity: risk factors and preventive measuresMatthiessen LW - Copenhagen University Hospital, Herlev, Denmark

Discussion

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10:35 - 11:00 Coffee break

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11:00 - 12:00head & neck cancerModerators: McCaul JA, Mozzillo N

Standard Operating Procedures in H&NOcchini A - Policlinico San Matteo, Pavia, Italy

EURECA protocol: preliminary resultsBertino G - Policlinico San Matteo, Pavia, Italy

ECT versus other local treatments of head and neck cancerDe Bree R - VU University Medical Centre, Amsterdam, The Netherlands

Early report on a phase II trial to evaluate the role and efficacy of electrochemotherapy on basal cell carcinomaSalwa S, Clover J, Kelly J, Bourke M, Soden D - Cork Cancer Research Centre, Cork, Ireland

Discussion

12:00 - 13:00MelanoMa Moderators: Peach H, Bernengo MG

ECT for disseminated superficial metastases from melanomaRossi CR - Istituto Oncologico Veneto - IRCCS, Padua, Italy

Clinical experience with subcutaneous metastases from sarcoma and melanomaRutkowski P - Marie Curie Hospital, Warsaw, Poland

Multimodal approach with ECT. Proposal for ECT melanoma user´s guidelinesFarricha V - Instituto Português de Oncologia, Lisbon, Portugal

Role of ECT in metastatic melanomaTestori A - Istituto Europeo di Oncologia, Milan, Italy

Discussion

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13:00 - 14:00 Lunch

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14:00 - 15:00MelanoMa perspectives Moderators: Cavalcanti A, Rossi CR

Multidisciplinary approach of metastatic melanoma: when electrochemotherapy?Bonadies A, Bucher S - Istituti Fisioterapici Ospitalieri - S. Gallicano, Rome, Italy

Long term results in melanoma patients and response associated predictive factorsQuaglino P - Università di Torino, Turin, Italy

Dendritic cells characterization in melanoma metastases after electrochemotherapy Gerlini G - Ospedale Santa Maria Annunziata, Florence, Italy

Electrochemoterapy and immunotherapy combination/sequencing:is there an abscopal effect?Ascierto P - Istituto Nazionale Tumori - Fondazione Pascale, Naples, Italy

Discussion

15:00 - 15:45pain control and nodules healingModerators: Schulze HJ, De Bree R

Predicting and managing pain in patients treated with ECT:results of the INSPECT registryQuaglino P - Università di Torino, Turin, Italy

Vascular effects of ECT and its implications in treatment of bleeding metastasesSersa G - Institute of Oncology, Ljubljana, Slovenia

Post-operative patient managementCuthbert C - St George’s Hospital, London, UK

Discussion

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15.45 - 16.00 Coffee break

16:00 - 17:00Sala Imperiale

head&neck cancerModerators: Remacle M, Benazzo M

Electrochemotherapy for extended cutaneous metastases and bulky deep tumours of head and neck areaGrau JJ - Hospital Clinic, Barcelona, Spain

Electrochemotherapy at Cardarelli Hospital: our follow up and new prospectsGargiulo M - Ospedale Cardarelli, Naples, Italy

Electrochemotherapy as palliative treatment in advanced inoperable head and neck cancer. Preliminary report in 38 casesLongo F - Istituto Nazionale Tumori - Fondazione Pascale, Naples, Italy

Electrochemotherapy for cutaneous and subcutaneous head and neck cancer: our experienceRossi P - Policlinico Tor Vergata, Rome, Italy

Electrochemotherapy in head and neck: clinical applicationsMcCaul JA - Royal Infirmary, Bradford, UK

Discussion

16:00 - 17:00 Sala Saturno

non MelanoMa skin tuMours Moderators: Rutkowski P, Guida M

Indications for electrochemotherapy in SCC, BBC and Kaposi sarcoma, based on results from a single institutionPennacchioli E - Istituto Europeo di Oncologia, Milan, Italy

Successful treatment of Gorlin-Goltz syndrome with bleomycin based electrochemotherapyKis E, Baltás E, Kinyó Á, Varga E, Gyulai R, Kemény L, Oláh J - University of Szeged, Szeged, Hungary

Efficacy of electrochemotherapy with bleomycin as a treatment for Gorlin-Goltz syndrome-related basal cell carcinomasGualdi G - Spedali Civili, Brescia, Italy

ECT in Merkel cell carcinoma, a new possibility to keep it under control, case reportKemper S - University Hospital, Münster, Germany

Loco-regional Merkel carcinoma treated with ECTCavalcanti A - Institut Gustave Roussy, Paris, France

Discussion

17:00 - 18:00Sala Imperiale

MelanoMaModerators: Moir G, Di Filippo F

Surgery and Electrochemotherapy: a new and fascinating integrationTauceri F, Tavaniello B, Framarini M, Di Pietrantonio D, Pinto V, Cavaliere D, Zannetti G, Verdecchia GM - Ospedale Pierantoni Morgagni, Forlì, Italy

European experience in Melanoma: results of INSPECT registryKunte C - Artemed Klinik, Munich, Germany

Adjuvant electrochemotherapy in melanoma patient: case reportBottoni U, Renne M - Università della Magna Graecia -Fondazione Tommaso Campanella, Catanzaro, Italy

Cell death by electrochemotherapy in melanoma metastasesBigi L, Galdo G, Cesinaro A, Vaschieri C, Truzzi F, Fantini F -Ospedale Manzoni, Lecco, Italy

The experience of the National Cancer Institute “Giovanni Paolo II” in BariGuida M - Istituto Giovanni Paolo II, Bari, Italy

Case report of complete healingStadler R - University Hospital, Minden, Germany

Discussion

17:00 - 18:00 Sala Saturno

non MelanoMa skin tuMoursModerators: Bucher S, Kis E

Cutaneous B-cell lymphomas treated with electrochemotherapyGatti A, Trevisini S, Veneri A, Bonin S, Signoretto D, Trevisan G -AOU Ospedali Riuniti, Trieste, Italy

Electrochemotherapy in Kaposi sarcoma: personal experience, considerations and suggestionsRotunno R - Policlinico Umberto I, Rome, Italy

Treatment of non-melanoma skin cancers with electrochemotherapy:a multicentre experienceAmerio P, Curatolo P, Quaglino P, Amatetti M - University G. d’Annunzio, Chieti, Italy

Treatment of keloids and hypertrophic scars with bleomycin and electroporationManca G - Spedali Civili, Brescia, Italy

Electrochemotherapy for massive keloids: the St George’s experienceOdili J - St George’s Hospital, London, UK

Discussion

18:00 - 19:00Sala Imperiale

clinical experiencesModerators: Corti L, Farricha V

Electrochemotherapy for melanoma and non-melanoma tumours: our experience at IRCCS San Martino-IST, GenoaPonte E - IRCCS San Martino, Genoa, Italy

Management of breast cutaneous metastases using electrochemotherapyBussone R - Ospedale Molinette, Turin, Italy

Electrochemoterapy as a local treatment in elderly patients: our experiencePellino G - Seconda Università di Napoli - Primo Policlinico, Naples, Italy

Healing reaction, local cancer and electrochemotherapy: a delicate balanceMuñoz Madero V - Hospital San Jaime, Torrevieja, Alicante, Spain

Electrochemotherapy in the treatment of cutaneous tumours: initial experience of the Papa Giovanni XXIII Hospital of Bergamo Piazzalunga D - Ospedale Papa Giovanni XXIII, Bergamo, Italy

Case report: extensive skin necrosis after ECT of breast cancer recurrenceMulier S - Chirec Cancer Center, Bruxelles, Belgium

Discussion

18:00 - 19:00 Sala Saturno

clinical experiencesModerators: Micheletti L, Gehl J

Feasibility and safety of electrochemotherapy of liver metastases from colon cancer not amenable to surgical treatmentBattaglia V, Coletti L, Bartolozzi C, Filipponi F - Azienda Ospedaliero Universitaria Pisana, Pisa, Italy

Electrochemotherapy for recurrent ovarian carcinoma: first clinical trialSurico D - Ospedale Maggiore, Novara, Italy

Role of electrochemotherapy in the treatment of recurrent carcinoma of the vulvaPerrone AM, Galuppi A, Cima S, Arcelli A, Pozzati F, Procaccini M, Pellegrini A, De Iaco P - Policlinico S Orsola, Bologna, Italy

Neoadjuvant and curative treatment by ECT in cutaneous cancers metastasesFabrizio T, Serio S, Ardito R, Troiani L, Aieta M and Orlandino G -IRCCS C.R.O.B., Rionero in Vulture, Italy

Recidivating basal cell carcinoma in both medial canthus, progressing to RT and surgical treatment. Complete response to ECTTutor EG - University Hospital, Guadalajara, Spain

Electrochemotherapy: experience in a large cutaneous metastases of breast cancerFanian F, Pauchot J, Montcuquet P, Humbert P - Jean Minjoz University Hospital, Besançon, France

Discussion

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20:30 Gala dinner

saturday, March 28:15 - 9:15

skin Metastases FroM breast cancer Moderators: Salzl G, Paradiso A

Literature review and Ljubljana experience in skin breast cancer metastasesSersa G - Institute of Oncology, Ljubljana, Slovenia

GISEL study group: experience in the treatment of breast cancer skin metastasesDe Laurentiis M, D’Aiuto M - Istituto Nazionale Tumori - Fondazione Pascale, Naples, Italy

Two cases of recurrent chest wall and scalp breast cancer metastasesThode MC - Center of Dermatology, Stuttgart, Germany.

Chest wall recurrence from breast cancer after mastectomyCampana LG - Istituto Oncologico Veneto - IRCCS, Padua, Italy

Discussion

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9:15 - 10:30advanced applications: deep seated tuMoursModerators: Gasbarrini A, Dughiero F

Electrochemotherapy in bone metastases: results of a phase II study Bianchi G, Campanacci L, Donati D - Istituto Ortopedico Rizzoli, Bologna, Italy

Intraoperative electrochemotherapy of colorectal liver metastases: A phase I/II studyEdhemovic I - Institute of Oncology, Ljubljana, Slovenia

Electrochemotherapy for deep and large soft tissue metastasesCampana LG - Istituto Oncologico Veneto - IRCCS, Padua, Italy

Local control of desmoid tumoursFazioli F - Istituto Nazionale Tumori - Fondazione Pascale, Naples, Italy

Applied treatment planning for clinical studies of ECT for deep seated tumoursKos B, Pavliha D, Marčan M, Serša G, Miklavčič D - University of Ljubljana, Ljubljana, Slovenia

Discussion

10:30 - 10:50 Coffee break

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10:50 - 12:05advanced applications: deep seated tuMoursModerators: Petrillo A, Bassi C

Preliminary experience with ECT in locally advanced pancreatic tumourIzzo F, Albino V - Istituto Nazionale Tumori - Fondazione Pascale, Naples, Italy

Endoscopic delivery of electroporation to colorectal cancerSoden D, O’Sullivan G, Forde P, Burke M, Buckley M, Clover J, Mahmud N, McNamara D - Cork Cancer Research Centre, Cork, Ireland

Planning and evaluation of treatment response with ECT in hepato-pancreatic tumours: quantitative methods of MRI (DCE-MRI and DW-MRI) versus PETGranata V, Filice S, Fusco R, Izzo F, Petrillo A -Istituto Nazionale Tumori - Fondazione Pascale, Naples, Italy

Treatment verification after electroporation in the brain using MRI Mahmood F, Hansen RH, Agerholm-Larsen B, Gissel H, Ibsen P, Gehl J - Copenhagen University Hospital, Herlev, Denmark

Additional data on the combination of bleomycin and cell membrane electroporationMir LM, - Centre National de la Recherche Scientifique, Institut Gustave Roussy, Paris, France

Discussion

12:05 - 13:05electroporation Mediated gene transFerModerators: Ciliberto G, Mir LM

Proof of concept of gene therapy using plasmid AMEP® in advanced/metastatic melanoma: safety and efficacy results of a phase I first-in-man studyAttali P, Spanggaard I, Snoj M, Cavalcanti A, Bouquet C, Sersa G, Robert C, Vasseur B, Gehl J - BioAlliance Pharma, Paris, France

Electroporation - its role in electro-gene-therapy for cancer immunotherapy and local tumour control - the USA veterinary experienceImpellizeri JA - Barrymore Center for Advanced Cancer Therapeutics, Veterinary Specialty Center of the Hudson Valley, New York, USA

DNA vaccination for chronic hepatitis B and C: optimizing DNA vaccine delivery using the Cliniporator™Saellberg M - Karolinska Institute, Stockholm, Sweden

Stable electroporation-mediated gene transfer into primary cells as treatment for age-related macular degenerationJohnen S, Walter P, Thumann G - RWTH Aachen University, Aachen, Germany

Discussion

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13:05 - 13:15closing reMarks

Cadossi R - IGEA, Carpi, Italy

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13:30 Lunch

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ectmeeting2013@igeamedical.com - www.igeamedical.com

CLINIPORATORLEADING CLINICAL ELECTROPORATION