Dr. Heekyung BAE€¦ · contents related to measurement analysis, test guideline, related data, ... Germany and Korea • 2016. 7. final Selection • Total €13,120,061 / year

2018. 1. 24. WED.

Dr. Heekyung BAE

1. Background

2. ACEnano Objectives and Contents

3. ACEnano Consortium

4. Progress with Overseas Institutions

For Better Chemically Yours Chemical Management Expert Group 3

1. Background : Needs of Domestic Nano-companies

4대 인프라 기능정비 및 확충투자공백구간의 위험부담 분담

Source : Nanotechnology Industrial Strategy (MIST/MoTIE/MoE, 2015.4)

Recently, in the "Nanotechnology Industrialization Strategy (2015)" report,

- Nano companies (570 companies surveyed, '14) believe that they are hoping to support technological

innovation infrastructure for the development of new products and sharing for risk on Investment gap with the

government(* Investment gap: the government is at the basic stage, and the private sector focuses on

commercialization investment, and there is investment gap between TRL4 ~ 7),

- In particular, obstacles to commercialization include: ① technical difficulties (long time span, high process

costs, etc.), ② difficulty in verifying safety performance, and ③ lack of information (lack of exchange between

technology and capital).


1. Background : Extending EU REACH Regulation

Consulting needs for nano materials and product registration to

be exported to the EU are expected to increase sharply

REACH : Registration, Evaluation, Authorization and restriction of Chemicals

It is a chemical substance management regulation that permits the registration evaluation

approval and restriction according to the manufacturing imports and risks for all substances

manufactured and imported in the EU within 1 ton per year since June 2018.

Obstacles to overcome for the expansion of the nano-industry market: EU-REACH


1. Background : Overcoming EU REACH Regulation

EU KOR USAJPN

CHN

Mex

Can

After 2018.05 with ACEnano Toolbox :

There is a pressing and urgent need for a tool to overcome the

anticipated EU-REACH regulatory barriers and the bottleneck

effects resulting from the nanomaterials and products industry.


1. Background : Need for International Cooperation

- The EU plays a leading role in regulating the safety of chemicals and nanomaterials. Therefore, by

establishing a network through joint research with EU research groups such as the ACEnano

consortium, we will be able to proactively respond to international standardization and new

regulatory trends in ISO TC 229, OECD WPMN, and ECHA led by EU researchers. It is absolutely

necessary to hold it.

- In order for domestic companies to participate in the ACEnano project as a partner and to secure

the right to use final products and to commercialize them later, they actively contribute to the

development of original technologies such as ACEnano WP1 & WP2 at a research institute with

original technology development capability (Hanyang Univ.) And an international cooperation

strategy that enables domestic participating companies to commercialize the final products (expert

system, education / training / consulting service contents) derived from WP3 & WP4.

“Need for International Cooperation”


2. ACEnano Objectives and Contents

Measurable key parameters

Online SOPs

Video protocols

Access to key relevant data

Consulting service for “Fit for

purpose” characterization

Consulting service for

nanomaterial

/nanoproduct registrations

Access to state-of-art analytical

techniques

Training service for

nanomaterial characterization

Market ?

Material ?

Tonnage ?

EU

Graphene

Oxide

1 ton/year

ACEnano

Toolbox

Expert system that optimizes various nanosafety related

contents related to measurement analysis, test guideline,

related data, registration of nanomaterials and products,

permission, and markings to user needs


3. ACEnano Consortium

• H2020 Proposal Call NMBP-26-2016

• Participated in 28 organizations in 10

countries including England, Austria,

Switzerland, Germany and Korea

• 2016. 7. final Selection

• Total €13,120,061 / year

• Focus on SMI participation and

international cooperation


3. ACEnano Consortium : Network

International standardization and regulatory bodies related to nanosafety

Major research groups for nanosafety in EU

ACEnano


3. ACEnano Consortium : Concept

Training core cohort experts

Community

training

3 EU locations

Roll-out online on-demand training and

proficiency tools

Streamlining of workflow

Guidance & Decision trees

Optimisation

& benchmarking

Method

Innovation

Data

gathering

from other projects

Data management

system & ontology

Phase 1

Phase 2

Toolbox BuildingTraining

cascade conceptData warehouse

building

NanoMILENanoLYSE &

NanoDefineNanoFASENANoREG I&II eNanoMapper OECD & ECHA

Easy access to key

relevant data

Skilled/proficient

endusers

Efficient “fit for purpose”

characterisation

Online SOPs &

video protocolsReliable key descriptors

ACEnano

Increased product confidence –

including “on market” processes

Data Warehouse

& provisioning toolbox

Phase 3


3. ACEnano Consortium : Working Packages

WP

6:

Dis

se

min

ati

on

& C

olla

bo

rati

on

s

WP

7:

Ma

na

ge

me

nt

& C

oo

rdin

ati

on WP1: Analytical innovation

WP3: Method benchmarking &

training

WP4: Linking ontology &

methodology

WP5: Quality assurance risk

assessment

WP2: Analytical optimisation

Delivering Anayltical Excelence

WP4ACEnano

WP6ACEnano

ACEnano

WP2ACEnano

WP3ACEnano

WP4ACEnano

WP1ACEnano

WP5ACEnano


3. ACEnano Consortium : Participation WPs

WP1 : Analytical

Innovations

WP2 : Analytical

Optimization

WP3 :

Benchmarking &

Training

WP4 : Linking ontology

&

methodology


3. ACEnano Consortium : Participating Domestic Institutions

Phase 1

Phase 2

Phase 3

- Application of Synchrotron-based

Soft X-ray Spectro-microscopy

analytical technology development

- Participated in Round Robin Test,

an international collaboration of

optimized analytical technology

- Participate in making decision

tree for nanomaterial analysis

HYU Contribution

Streamlining of workflow

Guidance & Decision trees

Optimisation

& benchmarking

Method

Innovation

ACEnano

Toolbox Building


3. ACEnano Consortium : Participation WPs - Institutions

WP1 : Analytical

Innovations

WP2 : Analytical

Optimization

WP3 :

Benchmarking

& Training

Application of Soft X-ray

Spectromicroscopic techniques

for the chemical imaging of

nanomaterials in biological,

environmental & product matrix

Microfluidic sample

preparation

Etc.

On-line size

separation/ surface

characterization

ToF-SIMS for

bionano interactions

CE for corona

characterization

QCM-D for corona

monitoring

Wide-Area illumination Raman

Spectroscopy

Microfluidic sample prep. &

delivery system

(LA)-SP-TOF-ICP-MS

Etc.

Reactivity assay on-

a-chip

Integration of

AFM/Raman/Confoc

al

FFF Sample

prep./intro. system

Integration of NTA-

FFF



Phase 1

Phase 2

Phase 3

- Nanosafety DB development

- Development of standardized data

template

- Extended development on Ontology

- Nanosafety DB management

system development

TO21 ContributionACEnano

Data Warehouse Building

Data gathering

Data management

system & ontology

Data Warehouse

& provisioning toolbox

- Consist of data warehouse

- Development nanosafety decision

making expert system



WP1 : Analytical

Innovations

WP2 : Analytical

Optimization

WP3 :

Benchmarking

& Training

WP4 : Linking ontology

& methodology



Phase 1

Phase 2

Phase 3

- Participated in Core Cohort Expert

- Education for practitioners in Asia

TO21 Contribution

ACEnano

Training Cascade Concept

Training Core

Cohort Expert

Community Training

3 EU location

Roll-out online on-demand

Training and Proficiency Tools

- Korean online training

and Proficiency Tool


WP1 : Analytical

Innovations

WP2 : Analytical

Optimization

WP3 :

Benchmarking

& Training

WP4 : Linking

ontology

&

methodology

WP6 : Dissemination &

Collaborations




- Commercialization technology promotion and external cooperation activities

- Promotion of “One Stop Solution” for dissemination and diffusion of technology development

- Designing networking system with ACEnano and international organizations

- Industrial support activities and program development

- Public relations technology promotion in Asia

- Promote ACEnano project to domestic experts and advisors through S2nano Workshop

- ACEnano – OpenTox - S2nano Workshop and ACEnano Coordinator Prof. Eva and WP4

Coordinator Dr. Hardy invited to Korea

- ACEnano Kick-off meeting, General Assembly Meeting and Networking

Development

Remarks


November 2~3th, 2017Venus room, SOL BEACH

SamcheokS2NANOWorkshop2017Nov

S2NANO Workshop (2017.Jan. & 2017.Nov.) were held to invitedomestic and overseas consultants such as KIST-Europe, douglas-Connect to promote technical cooperation on nanosafety



ACEnano-OpenTox-S2Nano Workshop (2017. 05)

The entire Consortium Coordinator, Prof. Eva Valsami-Jones and WP4 Coordinator, Barry Hardy visits South Koreaand discusses specific research plans in the future



“ACEnano Kick-Off Meeting, General Assembly meeting” attendance and networking

- Kick-off Meeting : 2017. Jan. Birmingham Univ., U.K.- General Assembly Meeting : 2017. Sept. Birmingham Univ., U.K.- Hanyang Univ. and TO21 researchers attended- To establish a close cooperation network with consortium participating organizations


“Kick-off Meeting”, 2017.1 “General Assembly Meeting”, 2017.9



- The ACEnano General Assembly Meeting, held every 6 months, was attended by

domestic researchers and conducted regular exchanges with overseas researchers

- WP2 : Participation in the regular WP2 Teleconference and participation in the

International Round Robin Test

- WP4 : The TO21 development team will collaborate with Douglas-Connect through a

Teleconference and a visit to Basel, Switzerland to jointly develop the ACEnano Toolbox

- WP6 : The NanoSafety Training Session will be held with ACEnano researchers at the

OpenTox Asia Conference, Scheduled to be held in Tokyo in May 2018, to provide a forum

for exchange between EU and Asian researchers

“Progress with Overseas Institutions”

Thank you!

Documents

Dr. Heekyung BAE€¦ · contents related to measurement analysis, test guideline, related data, ... Germany and Korea • 2016. 7. final Selection • Total €13,120,061 / year