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Urinary Incontinence Dr. Nedaa Bahkali 2012

Dr. Nedaa Bahkali 2012. Urinary incontinence is defined as involuntary leakage of urine

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Dr. Nedaa Bahkali 2012 Slide 2 Urinary incontinence is defined as involuntary leakage of urine. Slide 3 Stress urinary incontinence (SUI): involuntary urine leakage on exertion or with sneezing or coughing. Urge urinary incontinence: women have difficulty postponing urination urges and generally must promptly empty their bladder on cue and without delay. If urge urinary incontinence is objectively demonstrated by cystometric evaluation, the condition is known as detrusor overactivity (DO). Slide 4 Mixed urinary incontinence : When both stress and urge components are present, it is called. Slide 5 Prevalence of 25 - 55 %. Among women with urinary incontinence, the most common condition is stress incontinence, which represents 29 to 75 %of cases. Detrusor overactivity accounts for up to 33 % of incontinence cases. whereas the remainder is attributable to mixed forms. Slide 6 Slide 7 Detrusor muscle External and Internal sphincter Normal capacity 500-600cc First urge to void 150cc Slide 8 Slide 9 Slide 10 Storage Reflex Slide 11 Micturition Reflex Slide 12 o Age o Pregnancy o Childbirth o Menopause o Hysterectomy o Obesity o Chronically increased abdominal pressure Chronic cough Constipation Occupational risk o Smoking Slide 13 Pressure Transmission Urethral Support Slide 14 In an ideally supported urogenital tract, increases in intra-abdominal pressure are equally transmitted to the bladder, bladder base, and urethra. In women who are continent, increases in downward-directed pressure from cough, laugh, sneeze, and Valsalva maneuver are countered by supportive tissue tone provided by the levator ani muscle and vaginal connective tissue. Slide 15 In those with a weakened supportive "backboard", however, downward forces are not countered. This leads to funneling of the urethrovesical junction, a patent urethra, and in turn, urine leakage. Slide 16 Slide 17 Urethral support is integral to continenc (1) ligaments along the lateral aspects of the urethra, termed the pubourethral ligaments; (2) the vagina and its lateral fascial condensation; (3) the arcus tendinous fascia pelvic; (4) levator ani muscles. With loss of urethral support, the urethra's ability to close against a firm supportive backboard is diminished. Slide 18 Slide 19 Slide 20 Slide 21 History : Duration, severity, symptoms, previous treatment,(Urinary Frequency, Urinary Retention, volume of urine lost, Postvoid dribbling is classically associated with urethral diverticulum) medications, Past medical hx, GU surgery, Ob hx Voiding Diary Slide 22 Urge Incontinence Stress Incontinence Symptom No Yes Urgency No Yes Frequency with urgency Yes No Urine leakage with increased intra-abdominal pressures smallLarge Amount of urinary leakage with each incontinence episode YesOften No Ability to reach the toilet in time following an urge to void Seldom Usually Waking to void at night Slide 23 Diuretics Anticholinergics - antihistamines, antipsychotics, antidepressants Seditives/hypnotics Alcohol Narcotics -adrenergic agonists/antagnists Calcium channel blockers Slide 24 General Inspection and Neurologic Evaluation evidence of atrophy. neurologic evaluation of the perineum: bulbocavernosus reflex normal circumferential anal sphincter contraction, colloquially called an "anal wink", Slide 25 Pelvic Organ Prolapse Evaluation Slide 26 Q-Tip Test Slide 27 Urinalysis and Culture Postvoid Residual Cystometrics Uroflowmetry Slide 28 Slide 29 Conservative/Nonsurgical: Pelvic Floor Strengthening Exercises Pelvic Floor Muscle Training (PFMT) Slide 30 Electrical Stimulation Biofeedback Therapy Dietary Scheduled Voiding Estrogen Replacement Slide 31 Slide 32 Medications: Pharmaceutical treatment plays a minor role in the treatment of women with SUI. imipramine is reasonable to aid urethral contraction and closure. Recently, duloxetine a selective serotonin and norepinephrine reuptake inhibitor, has been evaluated for the treatment of SUI Slide 33 Slide 34 Periurethral Bulking Agents Slide 35 Retropubic Urethropexy Pubovaginal Slings Midurethral Slings Slide 36 Slide 37 Antimuscarinics: tertiary amines that act to block the muscarinic receptors in response to acetocholine First line Oxybutinin (Ditropan) Tolteridine (Detrol) Slide 38