Embed Size (px)
Citation preview
Breakthrough innovations that can save women and children now
D r i v i n g p r o g r e s s t o w a r D 2 0 1 5
PATH
/Eve
lyn
Hoc
kste
in
A special messageSince world leaders adopted the Millennium Development Goals (MDGs) in 2000, the proportion of people living in extreme poverty has been halved, more than 2.1 billion people gained access to improved sources of drinking water, and we have made remarkable advances in the fight against HIV/AIDs, malaria, and tuberculosis.
Despite such extraordinary improvements, progress remains very uneven, and too many vulnerable women and children have yet to share in the gains. Diseases that can be cured or prevented are still taking lives: diarrhea, pneumonia, malaria, HIV/AIDS, and tuberculosis. Pregnancy and childbirth, which should be sources of joy, remain all too threatening.
As we look to accelerate our progress on the health MDGs, the need for
innovation has never been more paramount. Harnessing cost-effective and lifesaving
technologies can have a vast impact
on the health of women and children,
help us reach those in countries or situations of greatest need, and tackle key areas of the Global Strategy for Women’s and Children’s Health.
Through the Every Woman Every Child movement, policymakers, donors, multilateral organizations, the private sector, civil society, and health care professionals are coming together to step up efforts to save lives and forge solutions that not only increase access to medicines and medical products but also promote sustainability.
This publication outlines ten innovations that will have an immediate impact on the leading killers of women and children. From new medicines that prevent deadly infections in newborns, to new uses of supply chains to deliver medicines to the most remote areas, these are game-changing practices and advances.
Identifying these technologies, however, is not enough on its own to save lives. We also need political will and financial commitment. More than a decade of progress tells me that further dramatic improvements are within reach, and I look forward to continuing to work with all partners to finish the job and build the future we want.
Ban Ki-moon Secretary-General of the United Nations
Uni
ted
Nat
ions
The odds of survival for women and children in many developing countries
are better than ever. Targeted global efforts to achieve MDGs 4 and 5
have driven steep declines in maternal and child mortality, allowing more
parents to celebrate their children’s birthdays each year. Achieving those
goals is within our reach—but getting there by 2015 means stepping up
our efforts to tackle the top killers of women and children worldwide.
This publication highlights ten breakthrough health innovations, from
products to systems approaches, ready to be used in developing countries
to help reach the MDGs. Paired with existing tools and others still in
development, these low-cost innovations have the potential to save
millions of lives by addressing the greatest health threats to women and
children in developing countries. But this potential cannot be realized
without the global health community banding together to provide access.
The good news is we can bring together the partnerships, resources,
and political will needed to protect the most vulnerable.
PATH
/Gab
e Bi
encz
ycki
Non
pneu
mat
ic
anti
shoc
k ga
rmen
t Po
stpa
rtum
hem
orrh
age
kills
mor
e m
othe
rs th
an a
ny o
ther
cau
se—
an
est
imat
ed 7
1,800
ann
ually
. An
anti
shoc
k ga
rmen
t—or
igin
ally
co
ncei
ved
by N
ASA
for u
se
in s
pace
—ca
n sl
ow e
xces
sive
bl
eedi
ng a
fter
chi
ldbi
rth
and
stab
ilize
th
e m
othe
r unt
il sh
e ca
n be
trea
ted
at a
n em
erge
ncy
care
faci
lity.
The
ga
rmen
t res
embl
es a
wet
suit
that
ca
n be
wra
pped
aro
und
the
mot
her’s
ab
dom
en a
nd lo
wer
bod
y to
dire
ct
bloo
d to
key
org
ans.
PAT
H h
as
wor
ked
wit
h co
llabo
rato
rs fr
om
the
Uni
vers
ity
of C
alifo
rnia
, San
Fr
anci
sco,
Pat
hfind
er In
tern
atio
nal,
and
Blue
Fuz
ion
Gro
up to
est
ablis
h hi
gh-q
ualit
y m
anuf
actu
ring
for t
he
garm
ent,
redu
ce it
s pr
ice,
incr
ease
pr
oduc
tion
, and
exp
and
acce
ss in
lo
w-r
esou
rce
sett
ings
.
Sim
plifi
ed d
osin
g of
m
agne
sium
sul
fate
Mag
nesi
um s
ulfa
te c
osts
less
than
a d
olla
r per
dos
e an
d is
the
mos
t eff
ecti
ve d
rug
to p
reve
nt a
nd tr
eat
life-
thre
aten
ing
conv
ulsi
ons
amon
g w
omen
wit
h se
vere
pr
e-ec
lam
psia
and
ecl
amps
ia—
preg
nanc
y-re
late
d co
ndit
ions
that
cla
im a
bout
63,
000
wom
en’s
live
s ea
ch y
ear.
But b
arrie
rs to
its
effec
tive
use
in d
evel
opin
g co
untr
ies—
incl
udin
g co
mpl
ex d
osin
g re
gim
ens,
a la
ck
of p
rodu
ct h
arm
oniz
atio
n, a
nd lo
w p
rovi
der f
amili
arit
y of
the
drug
—lim
it it
s po
tent
ial i
mpa
ct. T
o im
prov
e eff
ecti
ve u
se, s
ever
al g
roup
s in
clud
ing
Jhpi
ego,
PAT
H,
Mer
ck fo
r Mot
hers
, and
oth
ers
are
wor
king
wit
h th
e W
orld
Hea
lth
Org
aniz
atio
n an
d th
e U
N C
omm
issi
on
on L
ife-S
avin
g Co
mm
odit
ies
for W
omen
and
Chi
ldre
n to
cre
ate
mor
e us
er-f
riend
ly tr
eatm
ent r
egim
ens
and
mod
es o
f adm
inis
trat
ion
in lo
w-r
esou
rce
sett
ings
.
PATH/Patrick McKern
PATH
/Eve
lyn
Hoc
kste
in
Ten
heal
th
inno
vatio
nsto
sav
e liv
es n
ow
Chlo
rhex
idin
e fo
r um
bilic
al c
ord
care
Chlo
rhex
idin
e, a
low
-cos
t ant
isep
tic,
pr
even
ts d
eadl
y in
fect
ions
that
may
en
ter a
n in
fant
’s b
ody
thro
ugh
a ne
wly
cu
t um
bilic
al c
ord.
Few
oth
er
inte
rven
tion
s ha
ve a
s m
uch
prom
ise
to
rapi
dly
redu
ce n
ewbo
rn d
eath
s at
an
affor
dabl
e pr
ice—
less
than
$1 p
er d
ose.
Th
is y
ear,
7.1%
chl
orhe
xidi
ne d
iglu
cona
te
was
add
ed to
the
WH
O M
odel
Lis
t of
Esse
ntia
l Med
icin
es fo
r Chi
ldre
n, b
ut
regu
lato
ry a
nd m
anuf
actu
ring
hurd
les
rem
ain.
The
Chl
orhe
xidi
ne W
orki
ng G
roup
, an
inte
rnat
iona
l con
sort
ium
led
by P
ATH
, is
taki
ng s
teps
to im
prov
e ac
cess
and
hel
p av
ert m
any
of th
e hu
ndre
ds o
f tho
usan
ds
of d
eath
s ca
used
by
neon
atal
infe
ctio
n ea
ch y
ear.
Sim
plifi
ed d
osin
g of
m
agne
sium
sul
fate
Mag
nesi
um s
ulfa
te c
osts
less
than
a d
olla
r per
dos
e an
d is
the
mos
t eff
ecti
ve d
rug
to p
reve
nt a
nd tr
eat
life-
thre
aten
ing
conv
ulsi
ons
amon
g w
omen
wit
h se
vere
pr
e-ec
lam
psia
and
ecl
amps
ia—
preg
nanc
y-re
late
d co
ndit
ions
that
cla
im a
bout
63,
000
wom
en’s
live
s ea
ch y
ear.
But b
arrie
rs to
its
effec
tive
use
in d
evel
opin
g co
untr
ies—
incl
udin
g co
mpl
ex d
osin
g re
gim
ens,
a la
ck
of p
rodu
ct h
arm
oniz
atio
n, a
nd lo
w p
rovi
der f
amili
arit
y of
the
drug
—lim
it it
s po
tent
ial i
mpa
ct. T
o im
prov
e eff
ecti
ve u
se, s
ever
al g
roup
s in
clud
ing
Jhpi
ego,
PAT
H,
Mer
ck fo
r Mot
hers
, and
oth
ers
are
wor
king
wit
h th
e W
orld
Hea
lth
Org
aniz
atio
n an
d th
e U
N C
omm
issi
on
on L
ife-S
avin
g Co
mm
odit
ies
for W
omen
and
Chi
ldre
n to
cre
ate
mor
e us
er-f
riend
ly tr
eatm
ent r
egim
ens
and
mod
es o
f adm
inis
trat
ion
in lo
w-r
esou
rce
sett
ings
.
PATH
/Pat
rick
McK
ern
Hel
ping
Bab
ies
Brea
the
Saya
na®
Pres
sA
cces
s to
con
trac
epti
ves
supp
orts
fam
ily p
lann
ing
and
save
s liv
es
thro
ugh
heal
thy
birt
h sp
acin
g an
d th
e pr
even
tion
of u
nint
ende
d pr
egna
ncie
s. Y
et m
oder
n co
ntra
cept
ives
rem
ain
out o
f rea
ch fo
r mill
ions
of
wom
en. S
ayan
a® P
ress
is a
new
form
ulat
ion
and
pres
enta
tion
of
the
inje
ctab
le c
ontr
acep
tive
Dep
o-Pr
over
a® m
anuf
actu
red
by P
fizer
. Pa
ckag
ed in
the
Uni
ject
™ in
ject
ion
syst
em, S
ayan
a® P
ress
is s
impl
e fo
r hea
lth
wor
kers
to le
arn
and
adm
inis
ter—
and
it c
anno
t be
reus
ed,
elim
inat
ing
the
risk
of tr
ansm
ittin
g in
fect
ion.
Thi
s in
nova
tion
has
the
pote
ntia
l to
grea
tly
expa
nd a
cces
s to
a s
afe,
eff
ecti
ve, r
ever
sibl
e, a
nd
disc
reet
con
trac
epti
ve m
etho
d.
PATH
/Pat
rick
McK
ern
Hel
ping
Bab
ies
Brea
the
A b
aby’
s fir
st b
reat
h is
the
mos
t im
port
ant.
Hel
ping
Bab
ies
Brea
the,
an
init
iati
ve o
f the
Am
eric
an A
cade
my
of P
edia
tric
s an
d ot
hers
, is
wor
king
to tr
ain
1 mill
ion
birt
h at
tend
ants
to
ens
ure
ever
y ba
by ta
kes
its
first
bre
ath
no m
atte
r whe
re
they
are
bor
n. T
he p
rogr
am, w
hich
redu
ced
earl
y ne
wbo
rn
mor
talit
y by
as
muc
h as
47
perc
ent i
n Ta
nzan
ia, u
ses
inno
vati
ve te
achi
ng to
ols—
incl
udin
g La
erda
l’s N
eoN
atal
ie
new
born
sim
ulat
or—
to a
rm h
ealt
h w
orke
rs w
ith
sim
ple
supp
lies
and
know
ledg
e ne
eded
to s
afel
y de
liver
bab
ies
in
any
sett
ing.
Laer
dal G
loba
l Hea
lth
Kit Y
amoy
oW
e kn
ow h
ow to
trea
t dia
rrhe
a. Z
inc
and
oral
rehy
drat
ion
solu
tion
(ORS
) are
pro
ven,
aff
orda
ble
trea
tmen
ts, y
et d
iarr
hea
still
kill
s ne
arly
600
,000
chi
ldre
n an
nual
ly. I
n ru
ral a
reas
, it
’s o
ften
eas
ier t
o fin
d a
bott
le o
f Coc
a-Co
la th
an
thes
e lif
esav
ing
med
icin
es. C
olaL
ife
deve
lope
d Ki
t Yam
oyo
to b
undl
e an
d de
liver
zi
nc a
nd O
RS to
Afr
ican
ch
ildre
n by
pig
gy-b
acki
ng
on th
e be
vera
ge c
ompa
ny’s
de
liver
y sy
stem
and
loca
l soc
ial
mar
keti
ng. T
he k
it c
onta
ins
zinc
, O
RS, a
nd s
oap,
and
the
pack
agin
g se
rves
mul
tipl
e pu
rpos
es: a
m
easu
ring
guid
e, a
mix
ing
and
stor
age
devi
ce, a
nd a
cup
.
Bubb
le C
onti
nuou
s Po
siti
ve
Air
way
Pre
ssur
e de
vice
Mor
e th
an h
alf o
f pre
mat
ure
babi
es s
trug
gle
to
brea
the,
con
trib
utin
g to
the
fact
that
pre
mat
ure
birt
h is
the
lead
ing
caus
e of
new
born
dea
th. A
bu
bble
Con
tinu
ous
Posi
tive
Airw
ay P
ress
ure
devi
ce
can
save
live
s by
gen
tly
flow
ing
pres
suriz
ed a
ir in
to b
abie
s’ lu
ngs,
but
the
$6,0
00 p
rice
tag
is
too
expe
nsiv
e in
low
-inco
me
sett
ings
. Usi
ng a
n aq
uariu
m p
ump
to d
eliv
er a
ir an
d a
wat
er b
ottl
e to
relie
ve p
ress
ure,
Ric
e U
nive
rsit
y re
sear
cher
s de
velo
ped
a $4
00 v
ersi
on th
at s
igni
fican
tly
impr
oved
sur
viva
l rat
es a
mon
g ne
wbo
rns
in M
alaw
i.
Tom
my
Lave
rgne
, Ric
e U
nive
rsit
y
Cola
Life
ColaLife
LionsGate Technologies
Phon
e O
xim
eter
™It
’s d
ifficu
lt fo
r fro
ntlin
e he
alth
wor
kers
to
diag
nose
dis
ease
s lik
e pn
eum
onia
, whi
ch k
ills
m
ore
than
1 m
illio
n ch
ildre
n an
nual
ly, a
nd
pre-
ecla
mps
ia—
the
seco
nd-l
eadi
ng c
ause
of
mat
erna
l dea
th. T
he P
hone
Oxi
met
er™
, a m
obile
he
alth
pla
tfor
m d
evel
oped
by
the
Uni
vers
ity
of
Brit
ish
Colu
mbi
a an
d pa
rtne
r com
pany
Lio
nsG
ate
Tech
nolo
gies
will
hel
p ch
ange
that
. Usi
ng a
lo
w-c
ost s
enso
r pow
ered
by
a m
obile
pho
ne to
m
easu
re b
lood
oxy
gen
leve
ls a
nd th
en d
ispl
ayin
g in
form
ed a
dvic
e fo
r dia
gnos
is a
nd tr
eatm
ent,
this
de
vice
can
hel
p sa
ve m
othe
rs a
nd c
hild
ren.
ROTA
VAC
®Ro
tavi
rus
is th
e to
p ca
use
of d
eadl
y di
arrh
ea in
de
velo
ping
cou
ntrie
s, a
nd th
is y
ear,
an a
ffor
dabl
e ne
w v
acci
ne d
emon
stra
ted
its
abili
ty to
pro
tect
ch
ildre
n fr
om th
e di
seas
e. R
OTA
VAC
® w
as
deve
lope
d by
a c
ross
-sec
tor p
artn
ersh
ip le
d by
the
Gov
ernm
ent o
f Ind
ia a
nd c
ould
sav
e th
ousa
nds
of
child
ren
each
yea
r at a
cos
t of a
bout
$1 a
dos
e if
licen
sed
and
mad
e w
idel
y av
aila
ble.
Back
pack
PLU
SM
any
peop
le in
de
velo
ping
cou
ntrie
s m
ay n
ever
vis
it a
do
ctor
or h
ospi
tal.
Thei
r lin
k to
the
heal
th s
yste
m is
th
roug
h co
mm
unit
y he
alth
wor
kers
, who
w
ork
at th
e “l
ast
mile
” of
del
iver
y. T
he B
ackp
ack
PLU
S pr
ojec
t, a
pa
rtne
rshi
p am
ong
the
Uni
ted
Nat
ions
Chi
ldre
n’s
Fund
, Sav
e th
e Ch
ildre
n, M
DG
Hea
lth
Alli
ance
, fro
g de
sign
, and
oth
ers,
dev
elop
ed a
hol
isti
c to
olki
t to
em
pow
er h
ealt
h w
orke
rs a
nd s
ave
lives
. The
pr
otot
ype
incl
udes
med
icin
es, d
iagn
osti
cs, a
nd
heal
th s
uppl
ies
that
add
ress
life
-thr
eate
ning
di
seas
es li
ke p
neum
onia
and
mal
aria
, and
it
emph
asiz
es th
e ro
le o
f sup
ply
chai
ns, t
rain
ing,
and
su
perv
isio
n to
sav
e liv
es.
It’s
tim
e to
del
iver
on
our
prom
ises
to th
e w
orld
’s
wom
en a
nd c
hild
ren
Brig
ht id
eas,
suc
h as
the
inno
vati
ons
feat
ured
here
, are
am
ong
the
brea
kthr
ough
sol
utio
ns
need
ed to
end
pre
vent
able
mat
erna
l and
child
dea
ths.
Oth
er li
fesa
ving
tech
nolo
gies
in
deve
lopm
ent i
nclu
de a
dev
ice
to s
afel
y de
liver
babi
es d
urin
g ob
stru
cted
labo
r, ne
w p
acka
ging
of a
ntir
etro
vira
l dru
gs to
pre
vent
HIV
in
new
born
s, a
nd im
port
ant n
utri
tion
sup
plem
ents
that
sup
port
chi
ldre
n’s
grow
th. W
ith
thes
e an
d
othe
r hea
lth
inno
vati
ons,
we
have
the
pow
er to
save
4.6
mill
ion
lives
by
2015
.
But t
hese
bri
ght i
deas
won
’t s
ave
lives
by
them
selv
es. T
hey
need
to b
e de
liver
ed to
the
hand
s of
hea
lth
wor
kers
who
kno
w h
ow
to u
se th
em to
sav
e w
omen
, new
born
s,
and
child
ren.
Tha
t req
uire
s po
litic
al w
ill a
nd
finan
cial
com
mit
men
t.
The
solu
tion
s ar
e w
ithi
n ou
r rea
ch. T
he n
ext
step
s ar
e up
to u
s.
Let t
he w
orld
’s le
ader
s kn
ow th
at
we
can’
t wai
t any
long
er. S
hare
you
r th
ough
ts w
ith
#in
nova
tion
s201
5 an
d le
arn
mor
e at
ww
w.p
ath.
org/
inno
vati
ons2
015/
.
PATH
/Gab
e Bi
encz
ycki
Back
pack
PLU
S
Backpack PLUS
455 Massachusetts Avenue NWSuite 1000Washington, DC 20001USA
www.path.org
Learn more about innovations to save women, newborns, anD chiLDren
www.path.org/innovations2015/
September 2013
This publication was made possible by experts and innovators across the globe, as well as by:
PATH
/Gab
e Bi
encz
ycki
