2004, Rev Feb 2011

Emergency Drug Supply Dosing Guide 

Drug Indication/Use(s) Dosage Administration Aspirin (chewable) 81 mg tablet

Chest pain with suspect acute coronary syndrome1

162 mg to 325 mg1

Dextrose in Water 5% 500 mL

Dehydration2

IV administration: maximum infusion rate: 0.8 g/kg/hour.2

Sodium Chloride 0.9% 500 mL

Extracellular Fluid loss2

IV administration2

Dextrose 50% 500 mg/mL 50 mL Abboject

Hypoglycemia2 20–50 mL slow IV administration (3 mL/minute)2

Repeated doses may be required in severe cases.2

Diphenhydramine 50 mg/mL 1 ml vial

Hypersensitivity reactions2 Drug-induced extrapyramidal symptoms2

IM, IV: 10-50 mg per dose; single doses up to 100 mg may be used if needed2

Maximum daily dose is 400 mg.2 IV rate should not exceed 25 mg/minute.2

Epinephrine 1:1000 1 mL vial

Hypersensitivity reactions2

Initial: 0.1 mg -0.5 mg subcutaneously or IM (0.1 mL-0.5 mL of 1:1000 solution) [Do not exceed 1 mg (1 mL) per dose]2

For anaphylactic shock, doses may be repeated at 5-15 minute intervals.2

Epinephrine 1:1000 0.3 mL autoinjector

Hypersensitivity reactions (e.g. bee stings, foods)2

0.3 mg (0.3 mL) subcutaneously using autoinjector2

If anaphylactic symptoms persist, dose may be repeated in 5-15 minutes using an additional autoinjector.2

Lidocaine 1% 10 mg/mL 30 mL vial

Local anesthetic2 Percutaneous administration2 Single doses should not exceed 4.5 mg/kg or 300 mg (30mL). Do not repeat within 2 hours2

NOT FOR CARDIAC USE2

Naloxone 0.4 mg/mL 1 mL vial

Opiate-induced respiratory depression2 Acute opiate overdosage2

IV: 0.4-2 mg; may need to repeat doses every 2-3 minutes. If no response is observed after 10 mg, consider other causes of respiratory depression. Note:

IV push over 30 seconds is preferred. Also may be given IM, subcutaneously, and IV infusion.2

2004, Rev Feb 2011

Opioid-dependent patients may require lower doses (0.1 mg) titrated incrementally to avoid precipitating acute withdrawal.2

Nitroglycerin (NTG) (sublingual) 0.4 mg tablet

Acute relief of angina pectoris secondary to coronary artery syndrome1

Have the patient in a seated or lying down position. Dissolve 1 NTG tablet under the tongue. If chest pain/discomfort is unimproved or worsening after 5 minutes, call 9-1-1 immediately before giving additional NTG.1

Repeat NTG doses can be given every 5 minutes for a maximum of 3 doses while awaiting ambulance arrival.1

Charcoal in Sorbitol 4 oz slurry (25 gm charcoal/ 48 gms sorbitol)

GI decontamination2 Oral administration as directed by the Poison Center; most effective when administered within 30-60 minutes of ingestion.2

Contact Poison Center prior to administration 1-800-222-1222

Glucagon 1 mg/mL 1 mL vial

Hypoglycemia2 1 mg (1 mL) by IV, IM, or subcutaneous injection2

Use supplied diluent Discard any unused portion2

References

1. Anderson JL, Adams CD, Antman EM, et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non–ST-elevation myocardial infarction—executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to revise the 2002 guidelines for the management of patients with unstable angina/non–ST-elevation myocardial infarction). J Am Coll Cardiol 2007;50(7):652-726.

2. AHFS Drug Information [Internet]. Bethesda, MD: American Society of Health-System Pharmacists, Inc. 1959- [cited 2011 Feb 16]. Available from: http://online.lexi.com/crlsql/servlet/crlonline.