1
S306 IACAPAP 2012–20th World congress / Neuropsychiatrie de l’enfance et de l’adolescence 60S (2012) S254–S309 graphopathologie. Moins connu que les Bourneville, Jules Voisin, Sollier, Rou- binovitch, Dupré, décédé quelques mois avant l’ouverture du premier congrès de psychiatrie de l’enfant (1937) qui s’est tenu à Paris sous les hospices de Georges Heuyer, Marcel Manheimer qui, à partir de 1918 se dénommait officiellement sous le patronyme Marcel Gommès, fait parti de ces pionniers de la psychiatrie infantile franc ¸aise. http://dx.doi.org/10.1016/j.neurenf.2012.04.889 We-P-3244 Myopsychie dans un cas de dystrophie musculaire congénitale de type Ullrich D. Tiberghien , D. Bonnichon , S. Quijano-Roy , D. Leclair-Richard , B. Estournet-Mathiaud Centre de référence des maladies neuromusculaire, hôpital Raymond-Poincaré, Garches, France Auteur correspondant. Au cours du xx e siècle et encore maintenant, une des préoccupations majeures a été la constitution d’une nosographique des maladies neuromusculaires dont le cadre nosologique s’est élargie du fait des progrès réguliers de l’histologie, de l’histochimie, et la génétique, de la génétique moléculaire. Depuis le début des années 1980, les techniques de biologie moléculaire ont révolutionné la connais- sance des maladies neuromusculaires et permettent d’assigner une maladie à un gène en particulier. Des retards intellectuels, des troubles cognitifs et ou psy- chiatrique ont été décrits dans les maladies neuromusculaires. Parmi celles-ci, la Dystrophie Musculaire Congénitale (DMC) de type Ullrich (DCMU) est carac- térisée par un processus dystrophique lié à un déficit dans un des trois gènes codant le collagène VI, une des protéines constituant la matrice extracellulaire du muscle. Dans la DCMU, l’atteinte musculaire, précoce et de type dystro- phique comme dans toutes les DMC, prédomine au niveau des muscles du tronc (musculature axiale). Ceux-ci sont touchés plus précocement que les muscles des membres supérieurs ou inférieurs. Il existe une nette tendance à dévelop- per des rétractions. Elle n’est pas ou peu évolutive. Aucun trouble cognitif ou psychiatrique n’a jusqu’alors été rapporté dans cette entité. Nous rapportons, ici, l’observation d’un garc ¸on de 12 ans 6 mois présentant une dysharmonie évolutive de structure psychotique et qui, a l’âge de 13 mois a pré- senté un retard des acquisitions motrices. À 24 mois, une biopsie musculaire a confirmé le diagnostic de DMCU. L’IRM cérébrale était normale. Dès les pre- mières années de vie des indices psychopathologiques étaient déjà présent. Nous discuterons de la place des troubles psychiques au sein de cette maladie génétique et soulignerons qu’à côté de la surveillance orthopédique, cardiaque, respira- toire, la surveillance de l’état psychique doit faire partie de la prise en charge des maladies neuromusculaires dans le cadre de consultation pluridisciplinaire. http://dx.doi.org/10.1016/j.neurenf.2012.04.890 We-P-3245 Escitalopram and quality of life in older adolescents with anxious and depressive symptoms A. Tomac , T. Jakovina , S. Strbe , A. Razic Department of Psychological Medicine, University Hospital Center Zagreb, Zagreb, Croatia Corresponding author. Anxiety and depressive symptoms are the most common mental symptoms occurring during adolescence. According to the literature and clinical expe- rience untreated symptoms tend to extend to adulthood, which generates a serious public health issue. Despite high prevalence, these symptoms are rarely recognized for various reasons. Cipralex (escitalopram, Lundbeck S/A, SSRI antidepressant) is present in Croatia since 2002 in adults, indications: MDD, GAD, panic disorder w/o agoraphobia, social anxiety disorder and obsessive compulsive disorder. Aim of this naturalistic study was getting insight into Cipralex influence on quality of life (QoL) among adolescents with anxiety and depressive symptoms. We followed 20 adolescents, 18–21 years, who begun their psychiatric treat- ment at our Department. QoL was assessed with WHO quality of life scale (WHOQOL-BREF), on two occasions–before taking first dose of Cipralex, and after three months of regular usage. Preliminary results suggest improved quality of life and overall functioning in adolescents taking Cipralex. http://dx.doi.org/10.1016/j.neurenf.2012.04.891 We-P-3246 Comparing the criminal careers of female and male juvenile offenders from adolescence to middle age M.A. Forti-Buratti , T. Kramer Academic Unit of Child and Adolescent Psychiatry, Imperial College, London, UK Corresponding author. The aim of this study is to compare the 30-year criminal career characteristics of early (10- to 12-year-old) versus late (15- to 17-year-old) onset of female and male juvenile offenders. A cohort of 3636 juvenile offenders from Jan-Mar 1980 was identified from the Offenders Index with their subsequent 30-year history of offending. The criminal career of each individual was divided into four age periods and within each age period the total number of twelve different types of offending was recorded. The sub-groups were compared according to frequency and versatility of offending over time. We also calculated the severity-weighted frequency and versatility of each group for the whole criminal career and for each of the age-periods. Analysis of the similarities and differences in criminal career characteristics on the basis of gender and age at first conviction will be presented. Clinical implications will be discussed. http://dx.doi.org/10.1016/j.neurenf.2012.04.892 We-P-3247 Parental cardiovascular diseases as a risk factor for development of mental health problems in their children T. Jakovina , A. Tomac , A. Kordic , D. De Zan Department of Psychological Medicine, University Hospital Centre Zagreb, Zagreb, Croatia Corresponding author. During 2009, in Croatia, 25,976 people died (49.6% overall mortality) as a result of cardiovascular diseases (CAD), what is in accordance with WHO data, and represents a major public health problem. Clinical experience suggests the exis- tence of mental disorders in children and adolescents whose parents are suffering of CAD. These children usually ask for help when their psychological distur- bances have already become chronicle. Prevention, treatment and rehabilitation of CAD are primarily focused on the biomedical approach, but it is necessary to bear in mind the psychological superstructure and emotional disturbances in children of suffering parents. Specific developmental characteristics and dyna- mics of childhood and adolescence can be modified by parental illness, with an adverse effect on normal development and functioning (neurotic identification, parentification, separation anxiety). Considering all this, we suggest that all par- ticipants in the rehabilitation process of CAD should be acquainted with this phenomenon, what would enable the prevention or early intervention. http://dx.doi.org/10.1016/j.neurenf.2012.04.893 We-P-3248 The WHO EMR atlas: Country resources for child, adolescent and maternal mental health in the EMR H. Hamoda a,, K. Saeed b , C. Servili b , H. Madi b , M. Belfer c a Psychiatry, Children’s Hospital Boston, Harvard Medical School, Boston, USA b WHO EMRO, Cairo, Egypt c Department of Psychiatry: Fegan 8, The Children’s Hospital Boston, Boston, USA Corresponding author. The development of policies and programs for child and adolescent mental health clearly lag behind those for adult mental health. We present a study conducted by the WHO EMRO in collaboration with Children’s Hospital Boston to map child, adolescent and maternal mental health services in the Eastern

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Page 1: Escitalopram and quality of life in older adolescents with anxious and depressive symptoms

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306 IACAPAP 2012 – 20th World congress / Neuropsychiat

raphopathologie. Moins connu que les Bourneville, Jules Voisin, Sollier, Rou-inovitch, Dupré, décédé quelques mois avant l’ouverture du premier congrès desychiatrie de l’enfant (1937) qui s’est tenu à Paris sous les hospices de Georgeseuyer, Marcel Manheimer qui, à partir de 1918 se dénommait officiellement

ous le patronyme Marcel Gommès, fait parti de ces pionniers de la psychiatrienfantile francaise.

ttp://dx.doi.org/10.1016/j.neurenf.2012.04.889

e-P-3244

yopsychie dans un cas de dystrophie musculaireongénitale de type Ullrich. Tiberghien ∗, D. Bonnichon , S. Quijano-Roy , D. Leclair-Richard ,. Estournet-Mathiaud

Centre de référence des maladies neuromusculaire, hôpitalaymond-Poincaré, Garches, FranceAuteur correspondant.

u cours du xxe siècle et encore maintenant, une des préoccupations majeures até la constitution d’une nosographique des maladies neuromusculaires dont leadre nosologique s’est élargie du fait des progrès réguliers de l’histologie, de’histochimie, et la génétique, de la génétique moléculaire. Depuis le début desnnées 1980, les techniques de biologie moléculaire ont révolutionné la connais-ance des maladies neuromusculaires et permettent d’assigner une maladie à unène en particulier. Des retards intellectuels, des troubles cognitifs et ou psy-hiatrique ont été décrits dans les maladies neuromusculaires. Parmi celles-ci, laystrophie Musculaire Congénitale (DMC) de type Ullrich (DCMU) est carac-

érisée par un processus dystrophique lié à un déficit dans un des trois gènesodant le collagène VI, une des protéines constituant la matrice extracellulaireu muscle. Dans la DCMU, l’atteinte musculaire, précoce et de type dystro-hique comme dans toutes les DMC, prédomine au niveau des muscles du troncmusculature axiale). Ceux-ci sont touchés plus précocement que les muscleses membres supérieurs ou inférieurs. Il existe une nette tendance à dévelop-er des rétractions. Elle n’est pas ou peu évolutive. Aucun trouble cognitif ousychiatrique n’a jusqu’alors été rapporté dans cette entité.ous rapportons, ici, l’observation d’un garcon de 12 ans 6 mois présentant uneysharmonie évolutive de structure psychotique et qui, a l’âge de 13 mois a pré-enté un retard des acquisitions motrices. À 24 mois, une biopsie musculaire aonfirmé le diagnostic de DMCU. L’IRM cérébrale était normale. Dès les pre-ières années de vie des indices psychopathologiques étaient déjà présent. Nous

iscuterons de la place des troubles psychiques au sein de cette maladie génétiquet soulignerons qu’à côté de la surveillance orthopédique, cardiaque, respira-oire, la surveillance de l’état psychique doit faire partie de la prise en chargees maladies neuromusculaires dans le cadre de consultation pluridisciplinaire.

ttp://dx.doi.org/10.1016/j.neurenf.2012.04.890

e-P-3245

scitalopram and quality of life in older adolescents withnxious and depressive symptoms. Tomac ∗, T. Jakovina , S. Strbe , A. Razic

Department of Psychological Medicine, University Hospital Center Zagreb,agreb, CroatiaCorresponding author.

nxiety and depressive symptoms are the most common mental symptomsccurring during adolescence. According to the literature and clinical expe-ience untreated symptoms tend to extend to adulthood, which generates aerious public health issue. Despite high prevalence, these symptoms are rarelyecognized for various reasons. Cipralex (escitalopram, Lundbeck S/A, SSRIntidepressant) is present in Croatia since 2002 in adults, indications: MDD,AD, panic disorder w/o agoraphobia, social anxiety disorder and obsessive

ompulsive disorder. Aim of this naturalistic study was getting insight intoipralex influence on quality of life (QoL) among adolescents with anxiety

nd depressive symptoms.e followed 20 adolescents, 18–21 years, who begun their psychiatric treat-ent at our Department. QoL was assessed with WHO quality of life scale

WHOQOL-BREF), on two occasions–before taking first dose of Cipralex, and

Thct

l’enfance et de l’adolescence 60S (2012) S254–S309

fter three months of regular usage. Preliminary results suggest improved qualityf life and overall functioning in adolescents taking Cipralex.

ttp://dx.doi.org/10.1016/j.neurenf.2012.04.891

e-P-3246

omparing the criminal careers of female and maleuvenile offenders from adolescence to middle age.A. Forti-Buratti ∗, T. Kramer

Academic Unit of Child and Adolescent Psychiatry, Imperial College, London,K

Corresponding author.

he aim of this study is to compare the 30-year criminal career characteristicsf early (10- to 12-year-old) versus late (15- to 17-year-old) onset of female andale juvenile offenders. A cohort of 3636 juvenile offenders from Jan-Mar 1980as identified from the Offenders Index with their subsequent 30-year historyf offending. The criminal career of each individual was divided into four ageeriods and within each age period the total number of twelve different types offfending was recorded. The sub-groups were compared according to frequencynd versatility of offending over time. We also calculated the severity-weightedrequency and versatility of each group for the whole criminal career and forach of the age-periods. Analysis of the similarities and differences in criminalareer characteristics on the basis of gender and age at first conviction will beresented. Clinical implications will be discussed.

ttp://dx.doi.org/10.1016/j.neurenf.2012.04.892

e-P-3247

arental cardiovascular diseases as a risk factor forevelopment of mental health problems in their children. Jakovina ∗, A. Tomac , A. Kordic , D. De Zan

Department of Psychological Medicine, University Hospital Centre Zagreb,agreb, CroatiaCorresponding author.

uring 2009, in Croatia, 25,976 people died (49.6% overall mortality) as a resultf cardiovascular diseases (CAD), what is in accordance with WHO data, andepresents a major public health problem. Clinical experience suggests the exis-ence of mental disorders in children and adolescents whose parents are sufferingf CAD. These children usually ask for help when their psychological distur-ances have already become chronicle. Prevention, treatment and rehabilitationf CAD are primarily focused on the biomedical approach, but it is necessaryo bear in mind the psychological superstructure and emotional disturbances inhildren of suffering parents. Specific developmental characteristics and dyna-ics of childhood and adolescence can be modified by parental illness, with an

dverse effect on normal development and functioning (neurotic identification,arentification, separation anxiety). Considering all this, we suggest that all par-icipants in the rehabilitation process of CAD should be acquainted with thishenomenon, what would enable the prevention or early intervention.

ttp://dx.doi.org/10.1016/j.neurenf.2012.04.893

e-P-3248

he WHO EMR atlas: Country resources for child,dolescent and maternal mental health in the EMR. Hamoda a,∗, K. Saeed b, C. Servili b, H. Madi b, M. Belfer c

Psychiatry, Children’s Hospital Boston, Harvard Medical School, Boston,SAWHO EMRO, Cairo, EgyptDepartment of Psychiatry: Fegan 8, The Children’s Hospital Boston, Boston,SA

Corresponding author.

he development of policies and programs for child and adolescent mentalealth clearly lag behind those for adult mental health. We present a studyonducted by the WHO EMRO in collaboration with Children’s Hospital Bostono map child, adolescent and maternal mental health services in the Eastern