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ESMO Preceptorship Colorectal Cancer Barcelona …50-11:10 Coffee Break ... 30’ Adjuvant treatment for colon cancer III Claus ... ESMO Preceptorship Colorectal Cancer Barcelona November

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ESMO PRECEPTORSHIP PROGRAMME

COLORECTAL CANCER

Multidisciplinary management, standards of care and future perspectives

Barcelona, Spain 25-26 November 2016

CO-CHAIRS: Andrés Cervantes, Spain SPEAKERS: Frédéric Bibeau, France

Jean-Yves Douillard, Switzerland Michel Ducreux, France

Robert Glynne-Jones, United Kingdom

Claus-Henning Köhne, Germany

Pompiliu Piso, Germany

Hans-Rudolf Raab, Germany

Ramon Salazar, Spain

LEARNING OBJECTIVES

• To learn about best clinical practice in the multidisciplinary management of colorectal cancer in the adjuvant and

metastatic settings

• To understand the importance of pathology and histoprognostic factors

• To learn about the management of patients after progression, side-effects of treatments and in special situations

ACCREDITATION

The programme of this event has been accredited with 9 ESMO-MORA category 1 points.

Recertification is necessary for medical oncologists to remain professionally certified by ESMO. Recertification guarantees

that a certified medical oncologist has continued to update her/his knowledge and continues to possess the necessary

skills and standards for the practice of medical oncology. For further details, please refer to esmo.org.

ACKNOWLEDGEMENTS

This event is supported by an unrestricted educational grant from

ORGANISATION AND CONTACTS

ESMO Head Office Education Department Via Luigi Taddei 4 6962 Lugano - Viganello Switzerland Email: [email protected] www.esmo.org

Friday, 25 November 2016

09:00-9:15 15’

Welcome and introduction Andrés Cervantes, ES Jean-Yves Douillard, CH

09:15-10:50 95’

Session 1 Early colorectal cancer

Chair: Pompiliu Piso, DE

30’ The point of view of the pathologist

- - Quality and rules of a good pathology report

- - Histo-prognostic factors: Number of Lymph nodes, neural/lymphatic invasion, lymphocytic infiltration, MSH expression

Frédéric Bibeau, FR

20’ State-of-the-art: Standard of surgical practice for resectable colorectal cancer (special issues on rectal cancer)

Hans-Rudolf Raab, DE

30’ State-of-the-art: Standard(s) of radio/chemotherapy for rectal cancer Robert Glynne-Jones, UK

15’ Adjuvant chemotherapy of rectal cancer Andrés Cervantes, ES

10:50-11:10 Coffee Break

11:10-13:10 120’

Session 2 Adjuvant settings of colorectal cancer

Chair: Jean-Yves Douillard, CH

30’ Microsatellite instability and other molecular markers – how useful are they? Frédéric Bibeau, FR

30’ Adjuvant treatment for colon cancer III Claus-Henning Köhne, DE

30’ Adjuvant treatment of stage II: which patients to treat? Jean-Yves Douillard, CH

3x10’ 3 x Participant clinical case discussion All Faculty

13:10-14:10 Lunch

14:10-16:30 140’

Session 3 Metastatic colorectal cancer, liver limited metastases

Chair: Pompiliu Piso, DE

20’ Review of the ESMO consensus conference on metastatic colorectal cancer

- - Basic strategies and groups (RASwt /mut, BRAF mut)

Andrés Cervantes, ES

30’ Resection of liver limited metastases (Resectable cases, Group 0)

- - Upfront

- - After neo-adjuvant treatment

- - Repeated hepatectomy

Hans-Rudolf Raab, DE

30’ - Unresectable or borderline resectable (Group 1) chemotherapy +/- targeted agents

Claus-Henning Köhne, DE

30’ Options of locoregional treatment of liver metastases

- - Intra-arterial therapy

- - Chemo-embolisation

- - SIRT

- - Local radiation

Michel Ducreux, FR

3x10’ 3 x Participant clinical case discussion All Faculty

16:30-17:00 Coffee Break

17:00-18:30 90’

Session 4 Special clinical situations: Mono- or oligometastatic disease

Chair: Andrés Cervantes, ES

30’ Treatment of metastatic disease confined to the peritoneum

- - Resection

- - HIPEC

- - PIPEC

Pompiliu Piso, DE

30’ Primary with synchronous metastases Hans-Rudolf Raab, DE

30’ Chemotherapy and targeted agents in 1st line Ramon Salazar, ES

19:30 Dinner

Saturday, 26 November 2016

08:30-09:45 75’

Session 5 Metastatic colorectal cancer I

Chair: Jean-Yves Douillard, CH

50’ The role of maintenance, appropriate endpoints according to ESMO consensus Michel Ducreux, FR

25’ What to do after 1st line failure Andrés Cervantes, ES

9:45-10:15 Coffee Break

10:15-11:15 60’

Session 6 Metastatic colorectal cancer II

Chair: Andrés Cervantes, ES

30’ Management of treatment related side effects

- - GI-Toxicity

- - Neuropathy

- - Skin toxicity

- - Hypertension

- - Hand-foot syndrome

Michel Ducreux, FR

3x10’ 3 x Participant clinical case discussion All Faculty

11:15-12:00 45’

Session 7 Anal Canal tumours

Chair: Jean-Yves Douillard, CH

30’ Standard of care for Anal Canal Squamous carcinomas Robert Glynne-Jones, UK

15’ Salvage surgery of Anal Canal Squamous carcinomas Pompiliu Piso, DE

12:00-12:15 15’

Conclusion and farewell Chair: Andrés Cervantes, ES

12:15 Lunch

Note: Each 10 minute slot for clinical case discussion includes 5’ case presentation and 5’ Q&A / panel discussion