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Essential Imaging for Treatment of Acute Ischemic Stroke Stephan Duda

Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

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Page 1: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

Essential Imaging for Treatment of Acute Ischemic Stroke

Stephan Duda

Page 2: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

Ihre-Radiologen.de MVZ GmbH 2

None

Disclosures

Page 3: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

What do we need to know in acute stroke ?

Page 4: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

One-stop management?!?

Admission Neurological

ExamMDCT

+MDCTA

+rtPA

Angio Suite Groin

Puncture

Admission Neurological

ExamAngio Suite

FDCT

+FDCTA+rtP

A

Groin

Puncture

0:00 0:05 0:15 0:45 0:60

0:00 0:05 0:15 0:30

Direct transfer

angio suite

Page 5: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

Flat-Detector CT (FDCT)Cone-beam CT, C-arm CT, DynaCT, XperCT

MDCTFDCT

Page 6: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

Validation for hemorrhage

Detection of intracranial hemorrhage

MDCT (-) MDCT (+) Sensitivity Specificity

SAHFDCT (-) 61 2

95% 97%FDCT (+) 2 37

IVHFDCT (-) 68 1

97% 100%FDCT (+) 0 33

PHFDCT (-) 79 0

100% 99%FDCT (+) 1 22

Page 7: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

Enhanced XperCT Multi Detector CT

Images courtesy of Philips BV

Page 8: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

Comprehensive Stroke Diagnosis based on 3

Flat Detector CT Scans

Identify bleedingand ischemic changes

Identify proximal occlusion Identify collaterals

Non-contrast XperCT Early phase CE-XperCT Late phase CE-XperCT

Images courtesy of Philips BV

Page 9: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

Time management 2.0

Page 10: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

Results 2016-2018

One-stop cases 210 100

Door-to-CT 13 min 10 min

Door-to-Groin 26 25

Door-to-Reperf 70 68

Door-to-Reperf

M1 only60 59

courtesy of M. Psychogios

Page 11: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

Stroke. 2019;50:e344–e418

Page 12: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

Conclusion

Time management of stroke patients…

✓ …starts with symptom onset. If FAST-ED* >= 4, the EMS

should call the neurointerventionalist

✓ One-stop management is safe, with comparable sICH rates

even for „mothership“ patients without prior imaging

✓ “Direct to angio” leads to door-to-reperfusion times of

~60-70min and improved clinical outcomes of patients with

LVO

*FAST-ED: Field Assessment Stroke Triage for Emergency Destination

Page 13: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

Thank you!

Page 14: Essential Imaging for Treatment of Acute Ischemic …...even for „mothership“ patients without prior imaging “Direct to angio” leads todoor-to-reperfusion times of ~60-70min

Essential Imaging for Treatment of Acute Ischemic Stroke

Stephan Duda