EULAR COURSE ON IMMUNOLOGY 2018

6-7 April 2018

Lisbon, Portugal

EULAR Secretariat | Seestrasse 240 | 8802 Kilchberg | Switzerland MCI Switzerland | address | Geneva | Switzerland T: +41 44 716 30 30 | F: +41 44 716 30 39 T: +41 44 716 30 30 | F: +41 44 716 30 39 M: eular@eular.org | W: www.eular.org M: email | W: web

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ORGANISATION AND COMMITTEE

Scientific organiser

João Dias, Caroline Ospelt, Christophe Richez and Diane van der Woude

Scientific Content

This course will begin with introductory lectures to immunology, and will then give an update on the most recent concepts in adaptive and innate immunology and their relevance to rheumatic diseases. The course will focus on interactive learning and practical training, as reflected in the time dedicated for discussion and workshops.

Faculty

Ursula Fearon, Mariola Kurowska-Stolarska, Vivi Malmström, Xavier Mariette, Rene Toes

and Vania Sisirak

Organising secretariat

MCI

Contact person

João Dias, Caroline Ospelt, Christophe Richez and Diane van der Woude

EULAR Secretariat | Seestrasse 240 | 8802 Kilchberg | Switzerland MCI Switzerland | address | Geneva | Switzerland T: +41 44 716 30 30 | F: +41 44 716 30 39 T: +41 44 716 30 30 | F: +41 44 716 30 39 M: eular@eular.org | W: www.eular.org M: email | W: web

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GENERAL INFORMATION

Course venue

Nova Medical School, Lisbon, Portugal

Course opening

6 April 2018

Course closing

7 April 2018

Participants

Maximum number of participants: 40

This is an educational activity targeting young rheumatologists, dermatologists, internists

and researchers with basic and intermediate knowledge of immunology and strong

interest in translational research focusing on rheumatic diseases.

Selection criteria for attendees are:

- Young rheumatologist, internal medicine specialist or basic science researcher

working in the field of rheumatology

- Interest in immunology focusing on rheumatic diseases as indicated by a letter of

motivation in the application form

- The course is a selective course with competitive admission. Potential attendees will

send an application form, which includes a CV and a personal statement.

Official language

English

Registration fee

In order to facilitate attendance, costs and fees will be kept to a minimum. The participation

fee 280€, participants will include: the course, coffee breaks, lunch (first day), dinner out

(first day), lunch (second day), and two nights in a 4-star hotel with breakfast. For

participants requiring one-night accommodation the fee will be 210€.

Participants will have to pay their own flight / transportation.

EULAR Secretariat | Seestrasse 240 | 8802 Kilchberg | Switzerland MCI Switzerland | address | Geneva | Switzerland T: +41 44 716 30 30 | F: +41 44 716 30 39 T: +41 44 716 30 30 | F: +41 44 716 30 39 M: eular@eular.org | W: www.eular.org M: email | W: web

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Bursaries

Ten bursaries of 500€ will be distributed. These bursaries will be offered to support

applicants, which are supposed to have less financial support by their institutions. Applicants

can apply by sending a CV and a personal statement via the EULAR webpage

(https://www.eular.org/eular_course_on_immunology.cfm).

COURSE DESCRIPTION

Learning objectives

To increase knowledge and skills of young rheumatologists and basic researchers

working in the field of rheumatology in immunology.

To give to participants the opportunity to meet and exchange ideas and experiences

and therefore to foster international collaboration.

Basic training in how to design and conduct a translational research project

Course description

This is a compact, one and a half day course on immunology with a special emphasis on two hot immunology topics and on the design, interpretation and analysis of basic or translational research projects.

Three main sessions will be organized:

- Basic to Hot topic sessions (with 3 different lectures about adaptive or innate immunity)

- Discussion of a potential research project. Based on an unsolved research question posed by the faculty, the participants will draft a project using immunological investigational techniques (in vitro, in vivo). Via discussion with the faculty, the project will be improved and refined, so the participants will learn how to optimize approach, methods and controls.

- Immunology speed dating. This session will allow the participants to get together and with the faculty in a more ‘informal’ environment to share knowledge and ideas.

Course certification

A certificate of attendance will be supplied.

Course evaluation

There will be a formal evaluation of the course by attendees

EULAR Secretariat | Seestrasse 240 | 8802 Kilchberg | Switzerland MCI Switzerland | address | Geneva | Switzerland T: +41 44 716 30 30 | F: +41 44 716 30 39 T: +41 44 716 30 30 | F: +41 44 716 30 39 M: eular@eular.org | W: www.eular.org M: email | W: web

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PROGRAMME

EULAR Immunology Course – Programme

Friday 6 April, 2018

10:00 Registration desk opens

10:00-10:15 Arrival and welcoming by the faculties

10:15-10:30 Introduction: Prof. Jaime Branco - Professor in Rheumatology / Medicine at Nova

University

10:30-12:30

Basic to Hot topic session 1: Adaptive immunity

On the HLA, T cells and their clinical implications by René Toes (40 min of

lectures + 20 min of discussion)

Autoantibody maturation, antigen recognition and effector functions by Vivianne

Malmstrom (40 min of lectures + 20 min of discussion)

12:30-14:00 Lunch

14:00-15:00

Basic to Hot topic session 1: Adaptive immunity

Memory B cell response and its implication in auto-immunes diseases by Jean-

Claude Weill (40 min of lectures + 20 min of discussion)

15:00-16:00

Basic to Hot topic session 2: Innate immunity

Cellular and molecular mechanisms of tolerance break to DNA in SLE pathogenesis by Vanja Sisirak (40 min of lectures + 20 min of discussion)

16:00-16:30 Break

16:30-18:30 Immunology speed dating

18:30 Historical Lisbon Tour

21:00 Portuguese Dinner and networking activities

EULAR Secretariat | Seestrasse 240 | 8802 Kilchberg | Switzerland MCI Switzerland | address | Geneva | Switzerland T: +41 44 716 30 30 | F: +41 44 716 30 39 T: +41 44 716 30 30 | F: +41 44 716 30 39 M: eular@eular.org | W: www.eular.org M: email | W: web

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Saturday 7 April, 2018

08:00-10:00

Basic to Hot topic session 2: Innate immunity

Immunometabolism - a key mechanism involved in joint inflammation by Ursula

Fearon (40 min of lectures + 20 min of discussion)

Macrophage heterogeneity by Mariola Kurowska-Stolarska (40 min of lectures

+ 20 min of discussion)

10:00-10:30 Break

10:30-12:00

Workshop: Discussion of research projects

Group 1 – Mariola Kurowska-Stolarska/Ursula Fearon

Group 2 – Vivi Malmström/Vania Sisirak

Group 3 – René Toes/Jean-Claude Weill

12:00-12:15 Chairs’ summary and meeting closes

12:15-… Lunch and departure