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Evidence-based Dentistry Why Bother? Asbjorn Jokstad Institute of Clinical Dentistry, University of Oslo, Norway FDI World Dental Federation, Ferney-Voltaire, France

Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

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Page 1: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

1

Evidence-based Dentistry

Why Bother?

Asbjorn JokstadInstitute of Clinical Dentistry, University of Oslo, Norway

FDI World Dental Federation, Ferney-Voltaire, France

Page 2: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Teachers“Curriculum”

Advertising- producers- colleagues

Publicationsin

dentistry

The graduate

Page 3: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

• Already from day 1 the science in dentistry advances further - how to stay updated?

• Theoretic knowledge at zenith, from now on less time for reading / question of priorities

• No hands-on experience with many procedures common in modern dental clinics

- from where and how can further training be obtained?

The graduate• Has been taught and can perform many

basic procedures - not necessarily the most modern

Page 4: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

A rapidly changing society

The production of new knowledge in biomedicine is at maximum in historical context• Tremendous growth in

publications• Related to numbers of

physicians and scientists• Infomercial publications

Page 5: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Dental journals in circulation

0100200300400500600700800900

1000

1900 1910 1920 1930 1940 1950 1960 1970 1980 1990 2003

N=993

700 active200 ceased100 merged

Source: Ulrich’s International Periodicals Directory

Page 6: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

1. There is an Information Explosion in all fields of Biomedicine

Page 7: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

“Vitenskap”

Dental‘science’700 journals 25000 articles/y

Meetings/ courses

Colleagues

Dental literature

WWW

?!

Patients & (-groups)

Popular magazines & Media

Dentists’ daily situation: An information overload

Advertising- producers- colleagues

Page 8: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

2. We need to consider not only theamount

of information, but also thequality

of this information

Page 9: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

There is an Information Explosion in all fields of Biomedicine

Where and by who is new knowledge in oral sciences generated?

Page 10: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

The researchers

•Creates “scientific evidence”•Formulation of ideas, hypotheses, study design, data collection•Peer review, internal/external validity, debates within paradigms•Report findings in probabilities, not absolutes

Page 11: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

The clinical practitioners

•Single handed GPs/ specialists in teams; secondary/tertiary care•Great diversity of experience, interest and capacity •Draw on a panoply of experience•Pragmatism: what works - what creates problems

Page 12: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Developers of local guidelines and protocols

•Local consensus, sometimes on national guidelines •Clinical specialists seeking ways to influence peers

Page 13: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

The appraisers of evidence for clinical practice

•Epidemiologists, health economists, statisticians, social scientists, and clinicians •Collect, abstract and appraise practice related knowledge•Debates about value and balance between consensus and evidence, rigour of data and application of statistics

Page 14: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

A rapidly changing society

• The production of new knowledge is at maximum in historical context

• Incessant replacements of established ideas and concepts

Page 15: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

A rapidly changing society1.The production of new knowledge is

at maximum in historical context2. The quality of information varies3. Incessant replacements of

established ideas and concepts4. Information technology has

improved the potential for information transfer to everybody

Page 16: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

New patients?

Page 17: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Patient access to Information

Wish to remain sound, look healthy, different?…. young!!!Competitive health providers and information sourcesPatient information and communication

Page 18: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

5. General practitioners need information on

professional issues to meet the expectationsof educated patients in

this information age

Page 19: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

What would you answer be if ...

a 32 y patient calls four hoursafter a wisdom tooth has been removed and complainsabout bleeding, pain and severe swelling. She demands immediately some

analgetics, some antifebrilesand perhaps also antibiotics?...

Page 20: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

..or if ...a 66 year old woman comes to your clinic because she feels she hasn’t received any help from her former dentist about oral lichen planus. She wants to confer with you about a new Vietnamese Herbal Tea treatment described in the latest issue of ‘Health & Fitness’

Page 21: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Approaches when we’re uncertain • A patho-physiological appr.: this makes sense…• An expert / “how I was trained” approach: I learned this

worked / didn't work...• An anecdotal appr.: this didn't work last time..• A consultant approach: maybe I can ask a few

colleagues I work with….• A textbook approach: often outdated and no strong

support.• Confess that you don’t know - or - do something and

pray...• or invent some combination of approaches

Page 22: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Influences on treatment decisions

Resources

Dental PracticeExperience

Evidence

LitigationThe last patient

Education

Audit

Payment systems

Page 23: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Where can I find relevant clinical information when I need it fast?

• Can I consult a colleague?• Are my journals and textbooks

organised and updated? • Is a relevant library nearby?• Can I find the answers on the

Internet?

Page 24: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Altavista - webmedisin

20 links

Page 25: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Altavista - webmedisin

3675 links

Page 26: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Google - webmedisin

11900 links!

Page 27: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Medline - webmedisin

972 articles

Page 28: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Dentists’ environment: Overload of information!

Meetings/ courses

Colleagues

Advertising- producers- colleagues

“Vitenskap”

WWW

Patients & (-groups)

Popular magazines & Media

Dental‘science’700 journals: 25000 articles/y

Dental literature

6. A paradox

In spite of an information overload

…. only a small fraction is truly

appropriate for direct application

…. and we are ill equipped to digest

and synthesize this information

busy practice +reimbursement pressure

Page 29: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

1.Information explosion2.Quality of information3.No theories are constant 4.Educated patients with

access to information5.Daily information needs6.Paradox

Page 30: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

The situation for many dentists today

3. and traditional instructional continuing education courses do not improve our performance.

2. consequently, our clinical knowledge and performance in the clinic deteriorates

1. We need new information every day, but most of our needs are never met

Page 31: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Maybe this new thing EBM can be of any help?

Page 32: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Evidence Based Dentistry is the

1. Practice of a process of life-long….

2. problem-based learning in which devoted care for our patients creates a…

3. need for evidence about the…

4. cutting edge knowledge … concerning diagnosis, prognosis, therapy, and other clinical and health care issues.

(Adopted from Sackett et al.,1995)

Page 33: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Evidence Based Dentistry?!

An increasingly fashionable tendency of a group of young, confident, and highly numerate medical academics to defame the performance of experienced clinicians by using a combination of epidemiological jargon and statistical manipulation.

Page 34: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Evidence-based Practice:

Page 35: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Arguments, usually presented with near evangelistic zeal, that no health related action should ever be taken by a doctor, a nurse, a purchaser of health services, or a politician unless and until the results of several large and expensive Randomized Controlled Trials have appeared in print and approved by a committee of experts

Evidence Based Dentistry?!

Page 36: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Evidence-based Practice:

Page 37: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

• A strategy for being reasonably certain that my advises and treatment are the best available to my patients. - an ethical aspect

• A strategy for solving clinical problems on a daily basis.- a practical aspect

Two incentives for practicing Evidence-based Dentistry

Page 38: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Ethical reasons?COCHRANE LOGO: Corticostereoids and premature birth:

Lau et al. Streptokinase and myocardial infarction.N Eng J Med, 1992.

Cumulative Year RCTs PTs

1 231960

2 651965 3 149

4 3161970

7 179310 254411 2651

1975 15 331117 392922 545223 5767

198027 612530 6346

1985 33 657143 2105954 2205165 4718567 47531

1990 70 48154

P < .01

P < .001

P < .00001

Favours treatment Favours control Textbook / review recommendations

R S E NM215

1 101 22 8

78

1 121 8 41 7 3

5 2 2 115 8 16 1

0.5 1.0 2.0

Page 39: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Evidence Based Dentistry?!

The aim of evidence-based medicine is to eliminate the use of ineffective, expensive, or even dangerous medical decision-making

(Rosenberg & Donald, BMJ, 1995)

Page 40: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Evidence Based Dentistry

A strategy for how to cope with changes - not about knowing all the answers.

Not so much what you have read in the past…. but about…

how you should go about to identify and meet your ongoing learning needs… and applying the new knowledge appropriately and consistently in new clinical settings.

Page 41: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

How can evidence-based dentistry be integrated in our daily practice?

Page 42: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Practice of Evidence-based DentistryIdentify Problem –generate question

Act on Evidence

Search for Evidence

Make Sense of Evidence

Page 43: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

EBD practice1. Generate focused clinical questions

– On therapy, diagnostic tests, prognosis, harm, etc. (= PBL)

2. Efficiently find the evidence (=PBL)3. Determine validity, results,

applicability of evidence4. Apply the results of appraisal in

clinical practice / teaching5. Evaluate own performance

Page 44: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

How can we apply EBD in our daily practice?

1. By learning how to practice evidence- based dentistry ourselves–Books –Seminars–Internet

• Courses• Articles• Link banks

Page 45: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Modified from Haynes et al. BMJ 1998;317:273-6

Page 46: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,
Page 47: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

How can we apply EBD in our daily practice?

2. By seeking and applying evidence-based dentistry summaries generated by others

• Journals that critically appraise primary studies

• Systematic reviews

Page 48: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Modified from Haynes et al. BMJ 1998;317:273-6

Page 49: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Online secondary publication - EBD:

Page 50: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

0

50

100

150

200

250

1981

-19

85

1986

-19

90

1991

-19

95

1996

-20

00

2001

-20

02

(Cumulative)

N=236

Systematic reviews in dentistry

Page 51: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Cochrane Oral Health Group

• 250 members from 25 countries• Specialist trials register ~14,000

entries• Systematic reviews: near 90

http://www.cochrane-oral.man.ac.uk

Page 52: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

The Cochrane Collaboration

Page 53: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

2. By seeking and applying evidence-based dentistry summaries generated by others

• Secondary Journals • Systematic reviews• IADR: International Collaboration for

Evidence-based Dentistry

How can we apply EBD in our daily practice?

Page 54: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

How can we apply EBD in our daily practice?

3. By accepting and applying practice protocols, policies and guidelines based on evidence-based principles

Page 55: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Modified from Haynes et al. BMJ 1998;317:273-6

Page 56: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

Replaces original findings with subjectively selected, arbitrarily summarised, laundered and biased conclusions of indeterminate validity or completeness.

It has been carried out by people of unknown ability, experience, and skills using methods whose opacity prevents assessment of the original data.

Evidence Based Dentistry?!

Page 57: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

www.fdiworldental.org

Page 58: Evidence Based Dentistry - jokstad.no · 1 Evidence-based Dentistry. Why Bother? Asbjorn Jokstad. Institute of Clinical Dentistry, University of Oslo, Norway. FDI World Dental Federation,

58

Thank you for yourkind attention