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This article was downloaded by: [Universite De Paris 1]On: 05 September 2013, At: 12:24Publisher: RoutledgeInforma Ltd Registered in England and Wales Registered Number: 1072954 Registered office: Mortimer House,37-41 Mortimer Street, London W1T 3JH, UK
Psychotherapy ResearchPublication details, including instructions for authors and subscription information:http://www.tandfonline.com/loi/tpsr20
Existential dynamic therapy (“VITA”) for treatment-resistant depression with Cluster C disorder: Matchedcomparison to treatment as usualGry Stålsett a , Tore Gude a , M. Helge Rønnestad b & Jon T. Monsen ba Modum Bad Clinic, Research Institute, Vikersund, Norwayb Psychology, University of Oslo, Oslo, NorwayPublished online: 12 Jun 2012.
To cite this article: Gry Stålsett , Tore Gude , M. Helge Rønnestad & Jon T. Monsen (2012) Existential dynamic therapy(“VITA”) for treatment-resistant depression with Cluster C disorder: Matched comparison to treatment as usual,Psychotherapy Research, 22:5, 579-591, DOI: 10.1080/10503307.2012.692214
To link to this article: http://dx.doi.org/10.1080/10503307.2012.692214
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Existential dynamic therapy (‘‘VITA’’) for treatment-resistantdepression with Cluster C disorder: Matched comparisonto treatment as usual
GRY STALSETT1*, TORE GUDE1, M. HELGE RØNNESTAD2, & JON T. MONSEN2
1Modum Bad Clinic, Research Institute, Vikersund, Norway & 2Psychology, University of Oslo, Oslo, Norway
(Received 12 May 2011; revised 24 April 2012; accepted 25 April 2012)
AbstractExistential suffering may contribute to treatment-resistant depression. The ‘‘VITA’’ treatment model was designed for suchpatients with long-standing depression accompanied by existential and/or religious concerns. This naturalistic effectivenessstudy compared the VITA model (n �50) with a ‘‘treatment as usual’’ comparison group (TAU; n �50) of patients withtreatment-resistant depression and Cluster C comorbidity. The TAU patients were matched on several characteristicswith the VITA patients. The VITA model included existential, dynamic, narrative and affect-focused components. TheVITA group had significantly greater improvement on symptom distress and relational problems during treatment andfrom pre-treatment to 1-year follow-up. Patients in the VITA, at follow-up, were more likely to be employed and less likelybe using psychotropic medications.
Keywords: depression; spirituality and religion and psychotherapy; experiential/existential/humanistic psychotherapy;
psychoanalytic/psychodynamic therapy
Depression has become an epidemic disease of our
time (Honneth, 1995; Murray & Lopez, 1996;
WHO, 2010), affecting about 121 million people
worldwide, making it among the leading causes of
disability. Disturbingly, fewer than 25% of those
affected by depression have access to effective
treatment (WHO, 2010). Some of the barriers to
effective care include lack of trained providers, lack
of treatment options, and social stigma (American
Psychiatric Association Practice Guidelines for the
Treatment of Psychiatric Disorders, 2006). There is
also a lack of treatments matched to different types
of patients, different types of depression, and to
patients with comorbidity (e.g., Fava & Davidson,
1996; Fava & Rush, 2006; Guscott & Grof,
1991; Thase, 1996). Treatment-resistant depression
(TRD), often defined as no clear remission despite
more than three treatments, is a common clinical
presentation responsible for much of the burden of
major depressive disorder. TRD is estimated to
characterize more than one-third of depressed pa-
tients (Fava, 2003; Fava & Rush, 2006; National
Institue for Clinical Excellence, 2004). Clearly
there is a need for clinically relevant research on
treatment-resistant depression (Rush, Thase, &
Dube, 2003; Thase, 2001).
Many individuals with TRD have comorbid Clus-
ter C personality disorders, which might explain why
TRD is difficult to treat successfully (Driessen et al.
2010; Keitner, Ryan, Miller, Kohn, & Epstein, 1991;
Kornstein & Schneider, 2001; Petersen et al., 2002).
Cluster C personality disorders, which are character-
ized as anxious and fearful personality disorders, are
the most common personality disorders (American
Psychiatric Association, 2006) and complicate the
treatment of Axis I disorders; that is to say, patients
with Axis I disorders comorbid with Cluster C
personality disorders have poorer prognoses than
those without Cluster C comorbidity (Hardy et al.,
1995; Reich & Vasile, 1993; Shea et al., 1990). This
population of individuals*those with treatment-
resistant depression comorbid with Cluster C per-
sonality disorders (TRD/CCC)*do not function
well in society, as they are likely to be unemployed
or underemployed, have poor social relations
(e.g., being in dysfunctional relationships), rely on
government assistance, and entail high healthcare
costs. Clearly, this group of patients are personally
distressed and a burden to society in terms of cost,
Correspondence concerning this article should be sent to Gry Stalsett, Modum Bad Psychiatric Center, Badeveien Vikersund, 3370
Norway. Email: [email protected]
Psychotherapy Research, September 2012; 22(5): 579�591
ISSN 1050-3307 print/ISSN 1468-4381 online # 2012 Society for Psychotherapy Research
http://dx.doi.org/10.1080/10503307.2012.692214
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making it imperative that effective treatments be
identified and developed (Eaton et al., 2008; Moran,
2004; Murray & Lopez, 1996).
Individuals with TRD, whether or not comorbid
with Cluster C personality disorders, have by defini-
tion received prior courses of therapy for depression,
most likely antidepressant treatments as well as
evidence-based psychotherapies (e.g., CBT). Thus
these individuals have failed to respond to what are
considered first-line treatments for depression.
Although antidepressants and evidence-based pysh-
cotherapy have been shown to be effective treat-
ments for depression, it is clear that they are not
sufficiently effective for all individuals, as evidenced
by the prevalence of TRD. Consequently it is
necessary to employ other treatments and to develop
new treatments for this population.
In our clinical experience with TRD/CCC at
Modum Bad Clinic in Vikersund, Norway, we found
that many of these individuals expressed existential
issues involving religion, loneliness, meaningless-
ness, death, lack of freedom, fear of freedom, guilt
and shame. The existential orientation to psy-
chotherapy is grounded in the notion that pathology,
particularly anxiety and depression, is due to the
core issue of angst about the meaning of life and
death (Becker, 1973; Boss, 1979; May, Angel, &
Ellenberger, 1958; Schneider, 2007; Yalom, 1980).
The psychological function of a religious belief
system may serve as a primary means to ease
existential angst and manage the anxiety related to
the awareness of one’s mortality (see e.g., Vail et al.,
2011). Indeed, an intrinsic religious orientation,
which refers to an authentic internally motivated
faith and practice, is positively related to mental well-
being (e.g., Maltby & Day, 2000; Vail et al., 2011).
However, an extrinsic orientation to religion, which
refers to religious practices motivated by external
rewards (e.g., social status) or because it is required
for group membership, is related to neuroticism and
depression, racial prejudice and other indications of
psychological rigidity, and mitigates the adaptive
function of religion as a buffer to an existential fear
of death (Jonas & Fisher, 2006; Maltby & Day, 2004;
Vail et al., 2011). This is consistent with the
literature that suggests existential, spiritual or reli-
gious suffering can have a significant impact on
maintenance of depression and severe psychopathol-
ogy (e.g., Meissner, 1996; McConnel, Pargament,
Ellison, & Flanelly, 2006; Rizzuto, 1979).
Therefore it is worth considering treatments that
deliberately address religious and/or spiritual issues.
A recent meta-analysis by Worthington, Hook,
Davis, and McDaniel (2011) concluded that patients
receiving psychotherapies that accommodated the
patient’s religious and spiritual beliefs were efficacious
(i.e., superior to controls) on both psychological and
spiritual outcomes (e.g., being more like Jesus
Christ, spiritual well-being). However, this meta-
analysis also found that adding a spiritual and/or
religious component to already existing treatment
was not sufficient, as this addition had no effect on
psychological variables (although it did have an
effect on spiritual variables). Moreover, psychothera-
pies that are currently offered rarely directly address
existential issues (Ghaemi, 2001), and the concept of
God is often neglected as a topic in psychotherapy
(e.g., Bergin, 1991; Shafranske, 1996; Sperry &
Shafranske, 2005).
Based on our experience with TRD/CCC patients
at Modum Bad and the literature on psychological
issues related to religious/spiritual issues, we sought
to develop a treatment that integrated what is known
about treatment of depression and Cluster C per-
sonality disorders with a psychological focus on
existential and religious issues. The aim was to
integrate insights from the field of clinical psychology
of religion and existential psychotherapy (see Jones,
2010; Malitzky, 2010; Meissner, 1996; Richards,
2010; Rizzuto, 1979; Shafranske, 1992, 1996;
Stalsett, Engedal & Austad, 2010a; Yalom, 1980,
2007) rather than adding religious components (e.g.,
prayer, text from the Bible) to an already existing
treatment. The resulting treatment, which we called
VITA (so named because vita is Latin for life) is an
existential short-term dynamic group-oriented ther-
apy focused on the interweaving of affect, object
relations, narrative, and existential issues in a highly
structured inpatient program (see Stalsett et al.,
2010a).
In the first naturalistic effectiveness study of VITA
we determined that this new treatment approach was
safe, tolerated and effective (Stalsett, Austad, Gude,
& Martinsen, 2010). In this study, 40 patients*mostly suffering from depressive disorders with
additional anxiety and/or Cluster C personality
disorders*completed 12 weeks of the VITA treat-
ment. These patients experienced significant reduc-
tion in depressive symptoms and a reduction in
personality disorder symptoms at treatment termi-
nation and at 1-year follow-up, and had improved
occupational functioning at 1-year follow-up. The
patients’ relational patterns moved towards in-
creased self-representation (e.g., self-confidence,
self-worth, being active in the world) and reduced
submissiveness and over-conscientiousness. This
naturalistic study was inconclusive because it lacked
controls to rule out threats such as natural history,
regression toward the mean, etc. For example, it
might well have been that the 12-week stay in a
residential program provided sufficient respite from
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the stress of everyday life for these patients to show
remarkable improvement.
Before designing a randomized clinical trial of
VITA, we wanted to collect additional evidence
that VITA was effective. Therefore, we designed a
matched-comparison study in which patients treated
in VITA were compared to matched controls treated
at Modum Bad in a similar residential context, which
we termed treatment as usual (TAU). This study
addressed the following research question: Will
patients in VITA demonstrate greater improvement
on symptoms, interpersonal functioning, employ-
ment and medication use than matched comparison
TAU patients at post-treatment and at follow-up?
Methods
Design
The present study used a matched-comparative
study in a naturalistic setting to examine how
patients who experienced the VITA treatment model
performed at termination and 1-year follow-up
compared to patients who received treatment as
usual (TAU) in an earlier period at the hospital
before VITA was an option.
Participants
The study samples for the VITA and TAU groups
were recruited from patients admitted to Modum
Bad Clinic, Norway, a national hospital for non-
psychotic patients, often considered the ‘‘end-of-the-
line’’ for patients unresponsive to prior treatments.
Modum Bad offers specialized programs for a
variety of long-standing disorders including chronic
depression, typically with Axis II comorbidity, the
treatment for which involves a 3-month residential
program. At intake all patients were assessed, given a
diagnosis (either ICD or DSM), and completed
various screening instruments, including the Beck
Depression Inventory, the Symptom Checklist 90,
and the Inventory of Interpersonal Problems.
Patients participating in both treatments were
recruited from patients seeking treatment at Modum
Bad but who were not referred for specialized care
(e.g., referred to an eating disorder, panic, or
agoraphobia unit). Patients were exluded if they
exhibited or had recent history of destructive im-
pulsivity (i.e., were dangerous to self or others),
recent psychotic episodes, or recent suicide at-
tempts, as Modum Bad is not an acute clinic but
offers psychotherapy as a third line of the Norwegian
mental healthcare system. All patients who were
screened had prior unsuccessful combinations of
inpatient, outpatient, and medication treatment.
About 8% of persons applying for treatment at
Modum Bad met the inclusion criteria for TAU
and for VITA.
VITA Treatment Participants
Out of that pool of candidates who expressed
existential issues, 188 were referred for evaluation
for the VITA project on the basis of having indicated
in their application that religious or existential issues
were a long-lasting part of their mental distress. The
188 applicants were assessed during a two-day pre-
examination in which their ‘‘affect consciousness’’
for nine specific affects was assessed by the semi-
structured Affect Consciousness Interview (Monsen,
Eilertsen, Melgard, & Ødegard, 1996) to determine
whether their affective experience or affective orga-
nization was related to a representation of God. The
inclusion criteria were that the patients expressed
specific emotions (e.g., shame, fear, anger) related to
God, whether or not they believed in God, reported
existential issues related to psychological distress,
were depressed, were diagnosed with Cluster C
personality disorder, did not have other specific
diagnoses (e.g., eating disorders), were willing to
receive group therapy, and agreed to focus in therapy
on their existential and religious issues from a
psychological perspective.
In all, 72 patients met the criteria for the VITA
treatment and received the treatment. As described
below, 50 of these patients were included in the
present study based on being matched with patients
in the TAU group (i.e., only 50 patients could be
matched at the proper levels of the matching
variables with particular TAU patients). The Axis I
and Axis II diagnoses of the 50 patients in this
condition are presented in Table I. All of the patients
were diagnosed with depressive disorders (major
depressive disorder, dysthymic disorder, or depres-
sive scores above the clinical cutoff for depression on
the Beck Depression Inventory, i.e., above 15, mild
Table I. Axis I and II diagnoses at pre-treatment in matched
samples of VITA and TAU
VITA TAU
n % N %
Axis I
Major depressive disorder 40 80 30 60
Dysthymic disorder 15 30 16 32
Agoraphobia 6 12 1 2
Panic disorder 12 24 9 18
Social phobia 3 6 6 12
Generalized anxiety disorder 9 18 9 18
Axis II
Single Cluster C diagnosis 31 62 32 64
Multiple Cluster C diagnoses 19 38 18 36
VITA existential dynamic therapy 581
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depression) based on referral information and Mod-
um Bad clinical assessment. All patients received one
Cluster C diagnosis (n�31) or multiple Cluster C
diagnoses (n�19).
Treatment-as-usual participants. The com-
parison group (TAU) patients received treatment as
usual, a group-oriented therapy at Modum Bad
Psychiatric Center that was offered before the VITA
program was established. These patients completed
the outcome measues as part of a study of Cluster C
patients (Gude & Vaglum, 2001). The inclusion
criteria for these TAU patients were the same as for
the VITA group, except that the patients did not need
to reveal specific emotions (e.g., shame, fear, anger)
related to God although they may well have revealed
emotions related to God. The exclusion criteria were
identical to those for the VITA group (e.g., no
destructive impulsivity, recent psychotic episodes, or
recent suicide attempts, other specific disorders, etc.).
To develop a comparison group, 50 VITA patients
were successfully matched with 50 patients receiving
treatment as usual. Matching criteria were based on
diagnoses and on level of severity of pathology at
intake. Patients selected for the TAU group had to
have a depressive diagnosis (either major depressive
disorder, dysthymia, or depressive scores above the
clinical cutoff for depression on the Beck Depression
Inventory). Patients were also matched to VITA
patients based on their scores on the Beck Depres-
sion Inventory, the Symptom Checklist-90-R, and
the Inventory of Interpersonal Problems (see below
for description of the inventories).
Patient characteristics and demographics.
The diagnoses of the patients and the initial scores
on the inventories are presented in Table I and
Table II. The four TAU patients who did not meet
criteria for a DSM depression diagnosis had high
depression scores on the BDI. To ensure compar-
ability of the diagnoses in the two groups, two
psychiatrists, blind to treatment condition and not
involved in the treatment, independently reviewed
the pre-treatment charts and confirmed the depres-
sion diagnoses and Cluster C diagnoses for all
patients in VITA and TAU. The 50 VITA subjects
(29 women, 21 men) ranged in age from 28 to
62 years (m�43) and the 50 TAU subjects (28
women, 22 men) ranged in age from 23 to 57 years
(m�41). Both VITA and TAU patients reported an
average of three prior unsuccessful treatments. To
allay concerns that the 50 VITA patients who were
able to be matched with TAU patients differed from
the other 22 VITA patients, pretest scores on the
three outcome measures, as well as age and gender,
were compared. There were no significant differ-
ences on any variable (all p values �.28).
Assessment Measures
The following outcome battery was used for both
treatment conditions, at pre-treatment (T1), at post-
treatment (T2), and at 1-year follow-up (T3).
The Symptom Checklist-90. The Symptom
Checklist -90-R (SCL-90-R) has been widely used
in both clinical and research settings to evaluate
general psychopathology (Derogatis, 1977; Derogatis,
Lipman, & Covi, 1973; Smitz, Hartkamp, & Franke,
2000). The SCL-90-R is a 90-item self-report
symptom inventory for the assessment of psycholo-
gical symptoms and psychological distress scored
on a 0 (not at all) to 4 (extremely) scale. The Global
Severity Index (GSI), which is the mean score of
all items and is a global measure of psychological
symptoms and distress, was used in this study. The
test-retest reliability and internal consistency of
Table II. Means, standard deviations, effect sizes, and test statistics for outcome measures
Pre-treatment
(T1)
Post-treatment
(T2)
One-year
follow-up
(T3) Effect
size
Effect
size
Effect
size F time F treatment F T�T
Treatment condition Mean SD Mean SD Mean SD T1�T2 T2�T3 T1�T3
SCL-90-R
VITA 1.27 .54 .75 .49 .57 .41 1.01 .40 1.47
TAU 1.28 .51 1.01 .56 1.08 .60 .51 .12 .36 42.1*** 9.0** 11.3***
BDI
VITA 22.32 7.78 10.44 7.40 8.64 7.24 1.57 .25 1.80
TAU 20.06 8.50 14.94 9.11 16.74 10.82 .58 .18 .34 56.0*** 6.6* 16.1***
IIP
VITA 1.67 .63 1.30 .67 .99 .61 .57 .49 1.11
TAU 1.62 .51 1.46 .62 1.47 .59 .28 .02 .27 36.7*** 3.4 14.6***
Note. Effect size �Cohens d: (pretest mean � posttest mean)/SDpooled..
* pB.05, ** pB.01, *** pB.001.
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SCL-90-R have been found acceptable (Derogatis,
1977).
The Beck Depression Index. The Beck Depres-
sion Inventory (BDI: Beck, Steer, & Garbin, 1988) is
a widely used 21-item measure self-report instru-
ment for assessing severity of depression. Each item
is scored from zero (symptom not present) to three
(symptom experienced extremely); scores between
10 and 19 indicate mild depression, 20 to 29 indicate
moderate depression, and above 30 indicate major
depression.
The Inventory of Interpersonal Problems.
The Inventory of Interpersonal Problems (IIP;
Horowitz, Rosenberg, Baer, Ureno, & Villasenor,
1988) is a self-report instrument developed to assess
interpersonal problems. The present study used the
48-item version of the IIP, which was derived from
the original 127 items (Horowitz et al., 1988). This
48-item version has demonstrated adequate validity,
reliability, and internal consistency (Gude, Moum,
Kaldestad, & Friis, 2000). IIP is scored on a scale of
0 to 4. There are six subscales but only the mean
score of all items is reported in this study. The mean
total score for a non-clinical population was .53
(SD�.31; Pedersen, 2002).
Medication use and employment status. The
use of tranquilizers and anti-depressants as well
as employment status were assessed dichoto-
mously (0�not medicated/employed, 1�medicated/
employed) at pre-treatment and at follow-up. At pre-
treatment, medication use and employment status
were established by the referring physician and at
follow-up by a Modum Bad psychiatrist, based on
patient self-report.
Description of Treatments
VITA program. The VITA program’s main
components, as shown in Figure 1, involve an
Figure 1. VITA program components and strategies.
VITA existential dynamic therapy 583
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intensive study of affective connections in social
relationships among belief systems and ultimate
concerns (e.g., death, meaning, isolation, etc.) (see
Kernberg, 1988, 2000; Malan, 1979; Monsen &
Monsen, 1999; Rizzuto, 1979). Each existential
issue is addressed in relation to time (past, present,
and future), narrative construction (e.g., a broken
life or unlived life), relational space (e.g., alone, in
dyads, etc.), relational history, and defenses and
affects (Yalom, 1980, 2007; see also Spence,1982;
White & Epston, 1990).
The VITA program is designed to teach patients to
be mindful of affect by registering affects as events in
a non-judging way: ‘‘being aware in a ‘being mode’’’
(Kabat-Zinn, 1990; Segal, Williams, & Teasdale.
2002). Patients are encouraged to mentalize by
differentiating between one’s own affects and others’
(quite similar to Bateman and Fonagy, 2006, and
Fonagy, Gergely, Jurist and Target, 2002), and to
meta-reflect to obtain a broader and flexible per-
spective or ‘‘bird’s eye view’’ (some similarties to
metacognitive insight in Teasdale et al., 2002, and
Semerari et al., 2003). These strategies are hypothe-
sized as crucial to deal with patients’ existential
suffering and to address and loosen the grip of rigid
belief systems, often referred to as extrinsic orienta-
tion toward religion, that are embedded in their life
stories by acquiring a coherent understanding of how
existential suffering and rigid beliefs contribute to
their problems. As opposed to many treatments,
VITA directly addresses religious beliefs and their
dynamic origins.
VITA treatment activities (Figure 2) were carefully
designed to implement VITA strategies and achieve
the VITA goals. For example, art therapy develops
emotional awareness, integration and mentalization
by repeated painting of oneself, mother, father, and
God. Narrative groups share and transform percep-
tion and affect-related memories of key life stories.
Daily diaries process daily issues and enhance affect
processing and mindfulness. The End of Week
Reflection Group encourages ‘‘meta-reflection’’ on
universal concerns. The Daily Meditation (Mind-
fulness) Group trains patients in mindfulness to find
‘‘the quiet eye in the storm.’’ Physical exercise groups
are used to promote health and social activity.
Evaluation Groups assessed monthly treatment pro-
gress. Psychoeducation teaches the purpose and
importance of each program component. A more
complete description of VITA, including theoretical
bases, treatment integration, and case example, as
well as critiques, are found elsewhere (Jones, 2010;
Malitzky, 2010; Richards, 2010; Stalsett et al.,
2010a, 2010b).
Adherence to the VITA protocol was ensured in
several ways. First, two of the therapists in theVITA
program were developers of the treatment. Treat-
ment personnel had an agreement on treatment
principles and strategies, specific and detailed in-
structions for group activities existed and were
followed, and treatment developers (therapist as
well as non-therapist developers) and supervisiors
observed therapy live (through one-way mirrors) and
with videotapes. The treatment team and developers
met twice daily to discuss treatment adherence and
ensure that therapist actions were consistent with
VITA principles.
Figure 2. Comparison of treatment components in TAU and VITA.
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Treatment As Usual (TAU). The TAU group
was drawn from the regular Modum Bad inpatient
treatment programs. The treatment was, generally
speaking, psychodynamically based residential treat-
ment programs, with eclectically chosen cognitive
strategies, offered in group format augmented by
individual treatment once per week. The TAU
program was similar to VITA in its number of
activities and structure (see Figure 2), although
there was no psychoeducation for TAU as there
was for VITA. Instead, the TAU patients worked on
goal-setting with the nursing staff. The TAU group
received the same amount of dynamic group therapy
(twice a week), with staff behind a one-way mirror,
and individual therapy (once a week), but without
the deliberately intensive focus on object relations
(including God) and affects. Patients in the TAU
worked on dynamic issues often in a here-and-now
context, exploring feelings towards toward staff
members and other patients in different group
settings. Religious and existential issues were occa-
sionally reflected upon, but were not an intentional
treatment focus.
The TAU weekly activities are listed in Figure 2.
The TAU program activities were designed to
explore issues arising in group and individual ther-
apy. As in VITA, TAU dynamic group therapy
focused on interaction within the group; for exam-
ple, relational patterns were addressed to increase
patients’ awareness of their impact on behavior. Art
Therapy, as in traditional occupational therapy,
involved painting, crafts, woodworking, and collage
making, to elicit group issues and creative expres-
sion. Movement therapy encouraged bodily expression
of personal and relational topics, and Physical exercise
groups were designed to promote health and social
activity.
VITA and TAU differences and similarities.
VITA patients identified existential distress, isola-
tion, lack of meaning, shame and guilt, which were
often related to inner objects, whereas TAU patients
had not been screened in those terms. VITA and
TAU patients received in-depth examination of
affects through the Affect Consciousness Interview
(ACI; Monson et al., 1996), although VITA focused
on religious and spiritual/existential concerns in each
component of the program, whereas the TAU group
did not give systematic attention to existential issues.
Both VITA and TAU involved the standard
Modum Bad 3-month inpatient residential treat-
ment, with therapeutic interventions delivered dur-
ing the day. There were nursing staff on duty if TAU
patients wanted to talk during the night, but it was
optional. VITA patients did not have night staff
although there were general hospital staff members
on duty for emergencies. The night time differences
were due to different philosophies of care and not
because one group of patients was perceived as more
impaired than the other. The developers of VITA
believed that night staff facilitated dependency and
regression. Therefore the VITA program taught
patients to deal with suffering by writing in diaries,
excercising ‘‘mindfulness,’’ and working on ‘‘the
capacity to be alone’’ until they were able to speak
with staff during the day. The focus on autonomy at
night was a part of the VITA philosophy (noted in
Figure 2).
Medication in both conditions was managed by
the psychiatrist and nurse on staff. The personnel in
both groups attempted to reduce reliance on med-
ications to control symptoms, although this perspec-
tive was explicitly explained to the patients in VITA.
VITA and TAU Therapists
Both TAU and VITA utilized one psychologist, one
psychiatrist, one psychiatric nurse and one art
therapist. In the TAU condition, the personnel
occasionally changed between cohorts of patients.
The original VITA personnel had all been TAU
therapists, although when changes were made the
new personnel added to VITA had not been TAU
therapists. In TAU, one additional nurse served
during evenings and nights.
Statistical Analyses
To test whether the two treatment groups changed
differently on the SCL-90-R, BDI and IIP across
time, pre-treatment (T1), post-treatment (T2), and
1-year follow-up (T3), a repeated measures (pre-,
post-, follow-up) MANOVA was employed, with
particular attention to the treatment by time inter-
action. If the MANOVA yielded a significant
(p B.05) interaction term, the scores of each instru-
ment were analyzed separately with repeated-mea-
sures ANOVAs. To understand changes in each
phase, effect sizes were computed by taking the
difference of the means of the measures for the
respective phases and dividing by the pooled stan-
dard deviations (i.e., Cohen’s d; Cohen, 1977). Chi-
square tests were used for categorical data on
employment status and medication use.
Results
The means and standard deviations at pre-test, post-
test, and follow-up for the SCL-90-R, BDI, and IIP
are presented in Table II and illustrated in Figure 3.
The repeated measures MANOVA performed on the
SCL-90-R, BDI and IIP revealed a significant time
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Figure 3. Means scores for VITA and TAU at pretreatment, posttreatment, and follow-up.
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effect (F(6,93) �25.53, pB.001), a significant
treatment effect (F(3,96) �3.13, pB.029), and
a significant time by treatment interaction,
(F(6,93) �6.33, pB.001). Thus it appears that
patients in both groups improved but that the
VITA treatment was clearly superior to the TAU.
The significant effects in MANOVA led to the
following univariate analyses.
The univariate analyses yielded significant differ-
ences in scores on all three measures for effects of
time (SCL-90-R, F�42.1, pB.001; BDI, F�56.0,
pB.001; IIP, F�36.7, pB.001). The effects for
treatment were significant for the SCL-90-R and the
BDI (SCL-90-R, F�9.0, p�.003; BDI, F�6.6,
p�.01) but not for IIP (F�3.4, p�.67). Impor-
tantly, the time-by-treatment interactions were
highly significant for all three measures (SCL-
90-R, F�11.3, pB.001; BDI, F�16.1, pB.001;
IIP, F�14.6, pB.001).1
The pattern of change for VITA and TAU can be
understood by examining Figure 3 and Table II.
From pre- to post-treatment (T1-T2), VITA de-
monstrated medium to large effect sizes (viz., 1.01,
1.57, .57 for the SCL-90-R, BDI, and IIP, respec-
tively), while TAU showed small to medium effect
sizes (viz., .51, .58, .28 for the SCL-90-R, BDI, and
IIP, respectively). From post-treatment to follow-up
(T2-T3), VITA demonstrated small to moderate
effect sizes (viz., .40, .25, .49 for the SCL-90-R,
BDI, and IIP, respectively), while TAU showed small
effect sizes (viz., .12, .18, .02 for the SCL-90-R,
BDI, and IIP, respectively). The differences between
VITA and TAU are most apparent when the overall
change from pre-treatment to 1-year follow-up
(T1-T3) is examined. The effect sizes for VITA
improvement were very large (viz., 1.47, 1.80, 1.11
for the SCL-90-R, BDI, and IIP, respectively),
whereas TAU effects were small (viz., .36, .34, .27
for the SCL-90-R, BDI, and IIP, respectively). The
superiority of VITA at post-treatment was amplified
at follow-up because the VITA patients continued to
make progress after the treatment was terminated.
With regard to employment and medication, Table
III shows the proportions of employed, anti-depressant
use, and tranquilizer use at pre-treatment (T1) and
1-year follow-up (T3) for the VITA and TAU. The
increase in employment from pre-treatment to 1-year
follow-up was significantly higher in VITA than in
TAU (x2�9.49, p�.004); the decrease in medication
use from pre-treatment to follow-up was signficinatly
greater in VITA than for TAU (x2�32.00, pB.001
for antidepressants x2�25.00, pB.001 for tranquili-
zers). The reduction of medication use to 8% for the
VITA patients is quite remarkable given the initial use
of medication in this group was roughly twice as great
for these patients as it was for the TAU group before
treatment (44% v 20%).
Discussion
This naturalistic effectiveness study compared the
VITA model (n �50) with a matched ‘‘treatment as
usual’’ comparison group (TAU; n �50) for patients
with treatment-resistant depression and Cluster C
comorbidity (TRD/CCC) with existential and reli-
gious issues. The primary result is that patients who
received VITA showed remarkable improvement
relative to their initial level of functioning as well as
to TAU. First, there was significant improvement in
depression, general symptoms, and interpersonal
functioning in both the VITA and TAU groups
from pre- to post-treatment, although the effects
for VITA were roughly twice the size of the effects for
TAU. Second, VITA patients made significant gains
after completion of the treatment (i.e., from post-
treatment to 1-year follow-up) whereas the TAU
group maintained their gains but did not continue to
improve. TAU effects from pre-treatment to post-
treatment and follow-up were small to modest; that
is to say, improvement for the TAU patients was not
remarkable, whereas it appears that VITA patients
experienced relatively large benefits from the treat-
ment. Third, 1 year after treatment, patients in the
VITA group were much more likely to be employed
and less likely to be using psychotropic medication
relative to pre-test and relative to the TAU patients
at follow-up. That the VITA patients did not relapse
after termination but instead continued to improve,
a relatively rare event in the treatment of chronic
mental health disorders, should be noted. Consider-
ing the functional impairment of this population and
the associated costs to society, the promising results
of the VITA treatment should be noted.
Table III. Employment and use of medication at pre-treatment and 1 year follow-up
VITA TAU
Pre-treatment 1-year follow-up Pre-treatment 1-year follow-up Between treatment x2 at follow-up
Employed 8 (16%) 48 (96%)* 8 (16%) 37 (74%)* 9.49 pB.01
Antidepressant 22 (44%) 4 (8%)** 10 (20%) 31 (62%)** 32.00 pB.001
Tranquilizers 13 (26%) 0 (0%)*** 6 (12%) 20 (40%)*** 25.00 pB.001
*p B .05, **p B .01, ***p B .001.
VITA existential dynamic therapy 587
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It appears that VITA is a viable and effective
treatment for patients with treatment-resistant
depression comorbid with Cluster C personality
disorder and who have expressed existential and
religious issues as a significant part of their suffering.
It appears that VITA’s in-depth focus on blocked
affects (i.e., anger blocked by shame and guilt; see
Kernberg, 1988, 2000; Malan, 1979; Monsen &
Monsen, 1999; McCullough-Vaillant, 1994, 1997;
Rizzuto, 1979; Yalom, 1995) might have contributed
to the positive outcome in this study. Furthermore,
VITA’s development of affect integration (Monsen &
Monsen, 1999), regulation of affects through mind-
fulness (Kabat-Zinn,1990; Segal et al., 2002), men-
talization exercises (e.g., Fonagy et al., 2002;
Malitzky, 2010; Stalsett et al., 2010a), and emphasis
on meta-reflection might have built the capacity to
tolerate ambiguity in life and withstand the ups and
downs in living that often lead to relapse (e.g.,
Hanna & Ottens, 1995; Teasdale et al., 2002).
However, the present study is not sufficient to
identify active ingredients and consequently we
have started intensive process research to better
examine the process of change.
The major limitation of this study is that it is not a
randomized clinical trial. VITA patients may have
differed from TAU patients in openness and will-
ingness to address psychologically existential and
religious concerns, since only the VITA patients were
screened for that purpose to be included in a new
treatment approach. The VITA patients’ knowledge
that they were part of a new and special venture
within the hospital may have created expectancy
effects. As well, the VITA therapists, some of whom
were involved in the development of VITA, may have
been more enthusiastic, been more involved in the
treatment, had greater allegiance, and been more
confident that the treatment would be successful
than they were when they delivered the TAU.
Moreover, matching can never ensure comparability
in the way that randomization does and there could
be unobserved differences that account for the
obtained results.
There is an important limitation related to the unit
of analysis. The treatment was delivered in groups as
well as individual format, which creates a partially
nested structure*patients within therapists and
within groups. As is typical of such treatment
studies, the nested structure was not modeled, given
the small number of upper-level units and the
complex partial nesting (e.g., some members of a
group had different individual therapists). The issues
with expectancy and nesting might interact in that
the enthusiasm for the VITA treatment might have
created a more therapeutic interaction in the groups.
In this way, the enthusiasm of a single patient might
have affected the others in the groups.
There are a number of other methodological
limitations. The patient diagnostic method was not
constant, as some patients were diagnosed with
structured interviews and others were not; however,
the retrospective chart reviews were applied consis-
tently with all patients. All outcome measures were
self-report and there were no independent clinician
or assessor ratings. Outcome measures, although
varied (viz., symptoms, interpersonal functioning,
depression, medication use, and employment), did
not assess personality directly, which is a limitation
because the patients exhibited cluster C features.
Patients, when discharged, were referred to their
community outpatient services, but no information
was available for either group about type or intensity
of follow-up treatment, other than self-reported
medication use. The present study involved intensive
residential treatment and it would be important to
adapt and test the VITA treatment for outpatient
use.
Despite the limitations, particularly around the
issues of using a non-randomized control group, it is
important to note that the patients in the matched
comparison group (i.e., TAU) were selected based
on diagnoses, psychological symptoms, and inter-
personal functioning, and were treated in the same
institution, with a viable and accepted treatment,
with a comparable intensity of therapy. This study
met Leichsenring’s (2004) criteria for the highest
level of naturalistic studies and provides strong,
although preliminary, evidence for the effectiveness
of VITA. It is now appropriate for VITA to be tested
with a randomized clinical trial for treatment-resis-
tant depression comorbid with Cluster C patients
who express existential issues.
This treatment-resistant population may have
responded as well as they did to the VITA treatment
because they received what they came for, namely
to address their existential suffering and religous
ambivalence. Clinicians treating treatment-resistant
depression should consider addressing the psycholo-
gical functioning of patients’ internal representations
of God and their related adaptive or maladaptive
affect integration and relationships. The integrated
existential and psychodynamic focus on facilitating
a transformation of patients’ rigid inner representa-
tions of self and others tailored to individual
patients’ treatment needs has been shown to be
safe and well-tolerated. For more than three decades
Allen Bergin (1980, 1991; Bergin & Richards, 2000)
has challenged the psychotherapy community to
embrace and address religious issues and values
as important and potentially helpful aspects of
therapy.
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Acknowledgments
We are grateful for the contributions of Leigh
McCullough, John Roosevelt Boettiger, and Bruce
Wampold in conducting the research and preparing
the manuscript.
Note1 A potential threat to the validity of this study is that the 50 VITA
patients who were matched to the 50 TAU patients were not
representative of the 72 VITA patients. That is, the 50 patients
may be a biased sample of VITA patients. To examine this
threat, we also conducted the same analyses reported herein
with all 72 patients in the VITA conditions versus the 50 TAU
patients. For all three variables (viz., SCL-90-R, BDI and IIP)
the treatment (VITA vs. TAU) by time (pre, post, follow-up)
interaction were statisically significant (all psB.001).
References
American Psychiatric Association, APA. (1994). Diagnostic and
Statictical Manual of Mental Disorders: DSM IV. Washington
DC: American Psychiatric Association.
American Psychiatric Association Practice Guidelines for the
Treatment of Psychiatric Disorders. (2006). Washington DC:
American Psychiatric Association.
Bateman, A., & Fonagy, P. (2006). Mentalization-based treatment
for borderline personality disorder: A practical guide. Oxford:
Oxford University Press.
Beck, A.T., Steer, R.A., & Garbin, M.G. (1988). Psychometric
properties of the Beck Depression Inventory: Twenty-five years
of evaluation. Clinical Psychology Review, 8, 77�100.
Becker, E. (1973). The denial of death. New York: The Free Press.
Bergin, A.E. (1980). Psychotherapy and religious values. Journal
of Consulting and Clinical Psychology, 48, 95�105.
Bergin, A.E. (1991). Values and religious issues in psychotherapy
and mental health. American Psychologist, 46, 394�403.
Bergin, A.E., & Richards, S. (2000). Handbook of psychotherapy
and religious diversity. Washington DC: American Psychological
Association.
Boss, M. (1971/1979). Existential foundations of medicine and
psychology. New York: Jason Aaronson.
Cohen, J. (1977). Statistical power analysis for the behavioral
sciences. New York: Academic Press.
Derogatis, L.R. (1977). The SCL-90-R: Administration, scoring and
procedures. Manual I. Baltimore, MD: Clinical Psychometric
Research.
Derogatis, L.R., Lipmann, R., & Covi, L. (1973). SCL-90:An
outpatient psychiatric rating scale-preliminary report.
Psychopharmacology Bulletin, 19, 13�28.
Driessen, E., Cuijpers, P., de Maat, S.C., Abbass, A.A., de
Jonghe, F., & Dekker, J. (2010). The efficacy of short-term
psychodynamic psychotherapy for depression: A meta-analysis.
Clinical Psychology Review, 30, 25�36.
Eaton, W.W., Martina, S.S., Nestadt, G., Bienvene, O.J.,
Clarke, D., & Alexandre, P. (2008). The burden of mental
disorders. Epidemiological Review, 30, 1�14.
Fava, M. (2003). Diagnosis and definition of treatment�resistant
depression. Biological Psychiatry, 53, 649�659.
Fava, M., & Davidson, K.G. (1996). Definition and epidemiology
of treatment�resistant depression. Psychiatric Clinics of North
America, 19, 179�200.
Fava, M., & Rush, A.J. (2006). Current status of augmentation
and combination treatments for major disorder: A literature
review and a proposal for a novel approach to improve practice.
Psychotherapy and Psychosomatics, 75, 139�153.
Fonagy, P., Gergely, G., Jurist, G.L., & Target, M. (2002). Affect
regulation, mentalization and the development of the self. New
York: Other Press.
Ghaemi, N.S. (2001). Rediscovering existential psychotherapy:
The contribution of Ludwig Binswanger. American Journal of
Psychotherapy, 55, 51�64.
Gude, T., Moum, T., Kaldestad, E., & Friis, S. (2000). Inventory
of interpersonal problems: A three-dimensional balanced and
scalable 48-item version. Journal of Personality Assessment, 74,
296�310.
Gude, T., & Vaglum, P. (2001). One-year follow-up of patients
with cluster C personality disorders: a prospective study
comparing patients with ‘‘pure’’ and comorbid conditions
within cluster C, and ‘‘pure’’ C with ‘‘pure’’ cluster A or B
conditions. Journal of Personality Disorders, 15, 216�228.
Guscott, R., & Grof, P. (1991). The clinical meaning of refractory
depression: a review for the clinician. American Journal of
Psychiatry, 148, 695�704.
Hanna, F.J., & Ottens, A.J. (1995). The role of wisdom in
psychotherapy. Journal of Psychotherapy Integration, 5, 195�217.
Hardy, G.E., Barkham, M., Shapiro, D.A., Rees, A., Reynolds, S.,
& Stiles, W.B. (1995). Impact of Cluster C personality
disorders (Avoident, Dependent, Obsessive-Compulsive) on
outcomes of contrasting brief psychotherapies for depression.
Journal of Consulting and Clinical Psychology, 63, 997�1004.
Honneth, A. (1995). The struggle for recognition, the moral grammar
of social conflicts. Cambridge, MA: Polity Press.
Horowitz, L.M., Rosenberg, S.E., Baer, B.A., Ureno, G., &
Villasenor, V.S. (1988). Inventory of interpersonal problems:
Psychometric properties and clinical applications. Journal of
Consulting and Clinical Psychology, 56, 885�892.
Jonas, E., & Fischer, P. (2006). Terror management and religion.
Evidence that intrinsic religiousness mitigates worldview de-
fense following mortality salience. Journal of Personality and
Social Psychology, 91, 553�567.
Jones, J.W. (2010).Commentary on the persecuting God and the
crucified self: The case of Olav and the transformation of his
pathological self-image. Psychotherapeutic change and spiritual
transformation: The interaction effect. Pragmatic Case Studies in
Psychotherapy 6, 109�111. http://pcsp.libraries.rutgers.edu.
Kabat-Zinn, J. (1990). Full catastophe living.Using the wisdom of
your body and mind to face stress, pain, and illness. New York:
Dealcorte.
Keitner, G.I., Ryan, C.E., Miller, I.W., Kohn, R., & Epstein, N.B.
(1991). 12-month outcome of patients with major depression
and comorbid psychiatric or medical illness (compound
depression). American Journal of Psychiatry, 148, 345�350.
Kernberg, O.F. (1988). Object relations theory in clinical practice.
Psychoanal Quarterly, 57, 481�504.
Kernberg, O.F. (2000). Psychoanalytic perspectives on the
religious experience. Journal of Psychotherapy, 54, 452�476.
Kornstein, S.G., & Schneider, R.K. (2001). Clinical features of
treatment resistant depression. Journal of Clinical Psychiatry, 6,
18�25.
Leichsenring, F. (2004). Randomized controlled versus naturalis-
tic studies: A new research agenda. Bulletin of the Menninger
Clinic, 68, 137�151.
Malan, D. (1979). Individual psychotherapy and the science of
psychodynamics. London: Butterworth Press.
Malitzky, M.S. (2010). Commentary on the persecuting God and
the crucified self: The case of Olav and the transformation of
his pathological self-image. Dissolution of ‘‘The Committee’’:
mentalization and psychic transformation in the case of Olav.
Pragmatic Case Studies in Psychotherapy, 6, 118�125. http://
pcsp.libraries.rutgers.edu.
VITA existential dynamic therapy 589
Dow
nloa
ded
by [
Uni
vers
ite D
e Pa
ris
1] a
t 12:
24 0
5 Se
ptem
ber
2013
Maltby, J., & Day, L. (2000). Depressive symptoms and religious
orientation: examining the relationship between religiousity
and depression within the context of other correlates of
depression. Personality and Individual Differences, 28, 383�393.
Maltby, J., & Day, K. (2004). Should never the twain meet?
Integrating models of religious personality and religious
mental health. Personality and Individual Differences, 36, 1275�1290.
May, R., Angel, E., & Ellenberger, H.F. (Eds.). (1958). Existence:
A new dimension in psychiatry and psychology. New York: Basic
Books.
McConnel, K.M., Pargament, K.I., Ellison, C.G., & Flanelly, K.J.
(2006). Examining the links between spiritual struggles and
symptoms of psychopathology in a national sample. Journal of
Clinical Psychology, 62, 1469�1484.
McCullough-Vaillant, L. (1994). The next step in short term
dynamic psychotherapy. Psychotherapy, 67, 134�144.
McCullough-Vaillant, L. (1997). Changing character: An anxiety
regulating model of short term dynamic psychotherapy. New York:
Perseus Books.
Meissner, W.W. (1996). The pathology of beliefs and the beliefs of
pathology. In E.P. Shafranske (Ed.), Religion and the clinical
practice of psychology (pp. 241�267). Washington DC: American
Psychological Association.
Monsen, J.T., Eilertsen, D.E., Melgard, T., & Ødegard, P. (1996).
Affects and affect consciousness. Initial experience with the
assessment of affect integration. Journal of Psychotherapy
Practice and Research, 5, 238�249.
Monsen, J.T., & Monsen, K. (1999). Affects and affect
consciousness: A psychotherapy model integrating Silvan
Tomkins’s affect- and script theory within the framework of
self psychology. In A. Goldberg (Ed.), Pluralism in self
psychology: Progress in self psychology. Hillsdale, NJ: The Analytic
Press.
Moran, M. (2004). More workers getting treatment for depres-
sion, but it’s inadequate. Health Care Economics. Psychiatric
News, 39(6), 9�14.
Murray, C.J.L., & Lopez, A.D. (Eds.). (1996). The global burden of
disease. A comprehensive assessment of mortality and disability from
diseases, injuries, and risk factors in 1990 and projected to 2020.
Cambridge, MA: Harvard School of Public Health.
National Institute for Clinical Excellence. (2004) Depression:
Management of depression in primary and secondary Care. Clinical
Guideline 23. http://www.nice.org.uk/CG023NICEguideline.
Pedersen, G. (2002). Norsk revidert versjon av Inventory of
Interpersonal Problems-Circumplex (IIP-C). Tidsskrift for
Norsk Psykologforening, 39, 25�34.
Petersen, T., Hughes, M., Papakostas, G.I., Kant, A., Fava, M.,
Rosenbaum, J.F., & Nierenberg, A.A. (2002). Treatment-
resistant depression and Axis II comorbidity. Psychotherapy
and Psychosomatics, 71, 269�274.
Reich, J.H., & Vasile, R.G. (1993). Effects of personality disorders
on the outcome of axis I conditions. Journal of Nervous and
Mental Disorders, 181, 475�484.
Richards, P.S. (2010). Commentary on the persecuting God and
the crucified self: The case of Olav and the transformation of
his pathological self-image. The role of religion and spirituality
in Olav’s treatment and recovery: Commentary on an exemp-
lary case report. Pragmatic Case Studies in Psychotherapy, 6,
101�108. http://pcsp.libraries.rutgers.edu.
Rizzuto, A.M. (1979). The birth of the living God. Chicago: The
University of Chicago Press.
Rush, A.J., Thase, M.E., & Dube, S. (2003). Research issues in
the study of difficult-to-treat depression. Biological Psychiatry,
53, 743�753.
Schneider, K.J. (2007). Existential-integrative psychotherapy:
Guideposts to the core of practice. New York: Routeledge.
Schore, A.N. (1994). Affect regulation and the origin of the self. The
neurobiology of emotional development. Hillsdale, NJ: Lawrence
Erlbaum Associates.
Segal, Z.V., Williams, J.M.G., & Teasdale, J.D. (2002).
Mindfulness-based cognitive therapy for depression. A new approach
to preventing relapse. New York: Guilford.
Semerari, A., Carcione, A., Dimaggio, G., Falcone, M., Nicolo,
G., Procacci, M., & Alleva, G. (2003). Assessment. How to
evaluate metacognitive functioning assessment scale and its
applications. Clinical Psychology and Psychotherapy, 10, 238�261.
Shafranske, E. (1992). God-representation as the transforma-
tional object. In M. Finn & J. Gartner (Eds.), Object relation
theory and religion. Clinical applications (pp. 57�72). Westport,
CT: Praeger.
Shafranske, E.P. (Ed.). (1996). Religion and the clinical practice of
psychology. Washington DC: American Psychological Associa-
tion.
Shaap-Jonker, H., Eureling-Bontekoe, E., Verhagen, P.J., & Zock,
H. (2002). Image of God and personality pathology: An
exploratory study among psychiatric patients. Mental Health,
Religion and Culture, 5, 55�71.
Shea, M.T., Pilkonis, P.A., Beckham, E., Collins, J.F., Elkin, I.,
Sotsky, S.M., & Docherty, J.P. (1990). Personality disorders
and treatment outcome in the NIMH treatment of Depression
Collaborative Research Program. American Journal of
Psychiatry, 147, 711�718.
Smitz, N., Hartkamp, N., & Franke, G.H. (2000). Assessing
clinically significant change: application to the SCL-90-R.
Psychological Reports, 86, 263�274.
Spence, D. (1982). Narrative truth and historical truth: Meaning
and interpretation in psychoanalysis. New York: Norton.
Sperry, L., & Shafranske, E.P. (2005). Spiritually oriented
psychotherapy. Washington DC: American Psychological Asso-
ciation Press.
Stalsett, G., Austad, A., Gude, T., & Martinsen, E. (2010).
Existential issues and representation of god in psychotherapy:
A naturalistic study of 40 patients in the VITA treatment
model. Psyche & Geloof, 21, 76�91.
Stalsett, G., Engedal, L.G., & Austad, A. (2010a). The persecut-
ing God and the crucified self: The case of Olav and the
transformation of his pathological self�image. Pragmatic Case
Studies in Psychotherapy, 6, 49�100.
Stalsett, G., Engedal, L.G., & Austad, A. (2010b). Response to
commentaries on the persecuting God and the crucified self:
The case of Olav and the transformation of his pathological
self-image. Reflections on Olav’s therapy: The roles of religious
experience, self psychology, and metalization. Pragmatic Case
Studies in Psychotherapy, 6, 126�133.
Teasdale, J.D., More, R.G., Hayhurst, H., Pope, M., Williams, S.,
& Segal, Z.V. (2002). Metacognitive awareness and prevention
of relapse in depression: Empirical evidence. Journal of Con-
sulting and Clinical Psychology, 70, 275�287.
Thase, M.E. (1996). The role of Axis II comorbidity in the
management of patients with treatment-resistant depression.
The Psychiatric Clinics of North America, 19, 287�309.
Thase, M.E. (2001). The need for clinically relevant research on
treatment-resistant depression. Journal of Clinical Psychiatry,
62, 221�224.
Vail, K.E., Rothschild, Z.K., Wise, D.R., Solomon, S., Pyszcyns-
ki, T., & Greenberg, J. (2011). A terror management analysis of
psychological functions of religion. Personality and Social
Psychology Review, 14, 84�94.
Wampold, B.E. (2001). The great psychotherapy debate: Models,
methods and findings. Mahwah, NJ: Lawrence Erlbaum.
White, M., & Epston, D. (1990). Narrative means to therapeutic
ends. New York: Norton.
590 G. Stalsett et al.
Dow
nloa
ded
by [
Uni
vers
ite D
e Pa
ris
1] a
t 12:
24 0
5 Se
ptem
ber
2013
WHO. (2010). World Health Organization-WHO.int. http://www.
who.int/mental_health/management/depression.
Worthington, E.L. Jr., Hook, J.N., Davis, D.E., & McDaniel,
M.A. (2011). Religion and spirituality. Journal of Clinical
Psychology: In Session, 67, 204�214.
Yalom, I. (1980). Existential psychotherapy. New York: Basic Books.
Yalom, I.D. (1995). The theory and practice of group psychotherapy
(4th ed). New York: Basic Books.
Yalom, I.D. (2007). Staring at the sun. Overcoming the terror of
death. San Fransisco, CA: Jossey-Bass.
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