Facts and Figures

Facts and Figures 2009

CATEGORIES OF STAFF

Staff members: Recruited internationally as well as

locally. Their tenure is, in general, limited to a

maximum of nine years. Open-ended contracts can only be awarded in

exceptional cases.

Predoctoral and postdoctoral fellows:

They receive stipends either from EMBL or from

external institutions.

Supernumeraries: Employed for a limited time of a maximum of

one year. They are usually temporary replacements.

Ancillaries: Generally recruited from within the local labour market and

employed to support EMBL facilities, for

example housekeeping and cleaning services.

2

Contents Facts and Figures 2009

3Personnel and Visitors3 Personnel 7 Visitors

9Finance9 Financial data10 Member states’ contributions11 External funding 11 Annual accounts 2009 11 Grants 2009

12EMBL Leadership12 EMBL Council and Finance Committee 13 Scientific Advisory Committee 13 Bioinformatics Advisory Committee 14 Hamburg Priorities Committee 14 EMBL Directorate 15 Heads of Units/Senior Scientists 15 Senior Scientists 16 Faculty and Joint Appointments

20 23 24EMBL International PhD Programme20 PhD Theses 2009

Events23 Types of events23 Events in 2009

Collaborations

19Intellectual Property Rights19 Granted patents in 2009

3

Categories of Staff




exceptional cases.

Predoctoral and postdoctoral fellows: They receive stipends

either from EMBL or from external institutions.






Personnel and Visitors

PersonnelOn 31 December 2009, 1529 people, including visitors, from more than 60 nations were employed by EMBL.

Charts 1-10: The research units, other research activities and scientific support services are represented by charts showing categories of staff divided into ‘Staff Member’, ‘Postdoctoral Fellows’, ‘Predoctoral Fellows’ and ‘Other’. ‘Other’ includes ‘Ancillaries’ and ‘Supernumeraries’.

Chart 11: Staff distribution in research.

Chart 12: Staff distribution in non-scientific areas.

Chart 13: Staff nationalities in research units.

Chart 14: Nationalities of all staff.

1 2

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Personnel and Visitors cont.

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3

6

4

5

Other research activities include Directors’ Research, BIOMALPAR, ANTIMAL and EICAT

Scientific support services include Core Facilities and Laboratory Animal Resources


9

7

10

8

6


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11

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Categories of Visitors

Visiting Scientists: Scientists who need training

or to work on collaborative projects with an EMBL faculty member in the

specialised groups of the Laboratory, who wish to use them to evaluate possibilities for their own institution, or to undertake a specific project.

Trainees: Undergraduates from universities or

professional schools who do scientific, technical or administrative training at

EMBL.

Diploma Students: Undergraduates from

universities or professional schools who write their

diploma/masters thesis or equivalent at EMBL.

Visiting PhD Students: PhD students who are

not members of the EMBL International PhD Programme. Registered

with an external institution, they spend less than half

of the duration of their PhD at EMBL in order to benefit

from technologies and methods for specific parts of

their thesis.

Visiting scholars: Senior scientists who wish to be associated with a specific

group or Unit or with EMBL as a whole for a period of

study, reflection, writing and exposure to ongoing

research.

VisitorsIn 2009, 434 visitors came to the nine research units, the Core Facilities and administration (Chart 1) at the five EMBL sites. Chart 2 displays the distribution of visitor types.

The large majority of visitors came from EMBL member states, followed by non-European countries (Chart 3).

Chart 4 shows the 2009 beamline users at EMBL Grenoble. Chart 5 shows the users of the EMBL Hamburg beamlines.


1 2

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EMBL Grenoble collaborates with the ESRF to operate beamlines ID14-ID29. BM 14 is operated by a UK MRC–EMBL research consortium.

PX = protein crystallography SAXS = small angle X-ray scattering


5

3 4

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Financial data

Finance

10

Member states’ contributions

Finance cont.

In addition, one-off contributions were received as follows:

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External funding (grants)

Finance cont.

Annual accounts 2009Click here for a PDF of the complete accounts for 2009.

Grants 2009

Click here for pdfs of the EMBL grants (by funding body in 2009 (left) or by outstation (right)).

Other external funding

http://www.embl.de/aboutus/communication_outreach/publications/facts_figures/pdf/10_annual_accounts_2009.pdf

http://www.embl.de/aboutus/communication_outreach/publications/facts_figures/pdf/10_grants_by_funding_body_2009.pdf

http://www.embl.de/aboutus/communication_outreach/publications/facts_figures/pdf/10_grants_by_outstation_2009.pdf

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EMBL Council and Finance Committee on 31 December 2009

EMBL Leadership

EMBL Council is composed of delegates from all member states

of the Laboratory. Each member state is represented by up to

two delegates, who may be accompanied by

advisers. EMBL Council meets regularly twice a

year and has occasional extraordinary meetings.

One of the main responsibilities of

EMBL Council is to ensure that the financial requirements set up on

the establishment of EMBL are met, and the

site agreements with host member states are observed. The Finance Committee assists the Council in the financial

management and governance of EMBL.

Austria • Annemarie Frischauf, Delegate, Vice-Chair of Council • Elisabeth Tischelmayer, Delegate

Belgium • Marc van Montagu, Observer • Véronique Feys, Observer

Croatia • Kresimir Pavelic, Delegate • Vinko Purgar, Adviser

Denmark • Edel Bregnbæk, Delegate • Jørgen Kjems, Delegate

Finland • Kalervo Hiltunen, Adviser • Riitta Mustonen, Delegate • Eero Vuorio, Delegate France • Frédéric Dardel, Delegate • Julien Galabru, Delegate

Germany • Oda Keppler, Delegate • Reinhard Lührmann, Delegate • Paula Heppner, Adviser

Greece • Charalambos Savakis, Delegate, Chair of Council

• Theodore Fotsis, Delegate

Iceland • Hjördis Hendriksdottir, Delegate • Eiríkur Steingrímsson, Delegate • Katrin Valgeirsdottir, Adviser

Ireland • Fergal Cullen, Delegate • Stephen Simpson, Delegate • Graham Love, Adviser

Israel • Mahmoud Taya, Delegate • Joel Sussman, Delegate

Italy • Glauco P. Tocchini-Valentini, Delegate • Antonino Cianca, Adviser

Luxembourg • Josiane Entringer, Delegate

The Netherlands • Peter J. Weisbeek, Delegate • Jeannette Ridder-Numan, Delegate, Vice-Chair of Finance Committee

Norway • Anders Sundan, Delegate • Kjersti Sletholt, Delegate

Portugal • Maria José Almeida, Delegate (Finance Committee), Adviser (Council) • Maria Carmo-Fonseca, Delegate • Claúdio Sunkel, Delegate

Spain • Juan Modolell Mainou, Delegate, Vice-Chair of Council • Angela Nieto, Delegate • Luis E. Ruiz López de la Torre Ayllón, Delegate • Benjamin Sanchez Gimeno, Adviser

Sweden • Brita Beije, Delegate • Dick Heinegård, Delegate

Switzerland • Isabella Beretta, Delegate • Rolf Zeller, Delegate

United Kingdom • Mark Palmer, Delegate • Nigel Watts, Delegate, Chair of Finance Committee

Associate member: Australia • Katharine Campbell, Observer (primary delegate) • Richard Larkins, Observer

ˆ

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Scientific Advisory Committee

The Scientific Advisory Committee gives advice to Council, in particular with regard to proposals from the Director General on the realisation of the programme of the Laboratory. It is composed of distinguished scientists in their own right, not as representatives of member states.

Bioinformatics Advisory Committee

The Bioinformatics Advisory Committee gives advice to EMBL-EBI on scientific strategy, future directions and proposals on the realisation of its programme. It is composed of distinguished scientists in their own right, not as representatives of member states. Membership of the Committee is drawn from experts in the field of bioinformatics and other relevant scientific disciplines. Some are also members of EMBL’s scientific advisory committee and data resources advisory boards.

EMBL Leadership cont.

Anna Tramontano (Chairman) University of Rome “La Sapienza”

Rob CookeGlaxoSmithkline (also on the SABs for the Macromolecular Structure Database (MSD) and Protein Information Management System (PIMS))

Roderic Guigó Centro de Regulación Genómica, Barcelona

Olli Kallioniemi VTT Medical Biotechnology, Turku, Finland

John Sulston Wellcome Trust Sanger Institute

Mathias Uhlén Royal Institute of Technology, Stockholm

Martin VingronMax-Planck-Institut für molekulare Genetik (also Chairman of Array Express SAB)

Member Country Terms

Genevieve Almouzni Paris (FR) (2005-2007, 2008-2010)

Siv Andersson Uppsala (SE) (2007-2009)

Konrad Basler Zurich (CH) (2007-2009)

Roberto Di Lauro – Vice Chair

Napoli (IT) (2005-2007, 2008-2010)

Barry Dickson Vienna (AT) (2009-2011)

Herbert Jäckle Göttingen (DE) (2004-2006, 2007-2009)

Hiroaki Kitano Tokyo (JP) (2006-2008,2009-2011)

Werner Kühlbrandt – Chair

Frankfurt (DE) (2004-2006, 2007-2009)

Andrew Murray Harvard (US) (2008-2010)

Leena Peltonen Hinxton (UK) (2009-2011)

Helen Saibil London (UK) (2007-2009)

Sandra Schmid La Jolla (US) (2008-2010)

Titia Sixma Amsterdam (NL) (2007-2009)

Anna Tramontano Rome (IT) (2006-2008, 2009-2011)

Alfonso Valencia Madrid (ES) (2007-2009)

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Hamburg Priorities CommitteeThe Hamburg Priorities Committee evaluates project proposals for beamline access in macromolecular crystallography, small angle X-ray scattering and X-ray absorption spectroscopy.

EMBL DirectorateProf. Iain W. Mattaj, Director General

Dr. Bernd-Uwe Jahn, Administrative Director

Prof. Matthias Hentze, Associate Director

Dr. Christian Boulin, Coordinator of Core Facilities and Services

Dr. Silke Schumacher, Coordinator International Relations and Communications


Dino Moras IGBMC, Illkirch, France

Maria-Armenia Carrondo ITQB, Oeiras, Portugal

Bauke Dijkstra University of Groningen, The Netherlands

Ralf Ficner University of Göttingen, Germany

Mariusz Jaskolski Polish Academy of Sciences, Poznan, Poland

Andrew Leslie MRC Cambridge, United Kingdom

Poul Nissen University of Aarhus, Denmark

Gunter Schneider Karolinska Institute, Stockholm, Sweden

Ritva Serimaa Vikii Centre, University of Helsinki, Finland

Patrice Vachette University Paris-Sud, Orsay, France

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Heads of Units/Senior Scientists

Heads of Units participate in the collegial leadership

of EMBL and play a critical role in the research

direction of their unit. They lead a research

group, mentor younger faculty members and

ensure the maintenance of world class standards

of research throughout their unit.

Senior Scientists are a select group, with important statutory

responsibilities for advising the Director General on

faculty appointments and promotions. They also

provide collective advice to the Director General

and the heads of units on matters with significant

impact on the scientific life of the Laboratory.


Peer Bork Joint Head of Unit Structural and Computational Biology

Christian Boulin Coordinator of Core Facilities and Services Scientific Services & Core Facilities

Graham Cameron Associate Director EMBL-EBI

Stephen Cusack Head of Unit EMBL Grenoble Genome Biology Unit

Jan Ellenberg Joint Head of Unit Cell Biology & Biophysics

Anne Ephrussi Head of Unit / EiCAT Coordinator Developmental Biology

Eileen Furlong Joint Head of Unit Genome Biology Unit

Matthias Hentze Associate Director of EMBL Directors’ Research Molecular Medicine Partnership Unit

Eric Karsenti Joint Head of Unit Cell Biology & Biophysics

Iain Mattaj Director General Directors’ Research

Christoph Müller Joint Head of Unit Structural and Computational Biology Genome Biology Unit

Nadia Rosenthal Head of Unit EMBL Monterotondo Developmental Biology

Lars Steinmetz Joint Head of Unit Genome Biology Unit

Janet Thornton Director EMBL-EBI

Matthias Wilmanns Head of Unit EMBL Hamburg

Rolf Apweiler EMBL-EBI

Detlev Arendt Developmental Biology

Ewan Birney EMBL-EBI Genome Biology

Alvis Brazma EMBL-EBI

Nick Goldman EMBL-EBI

Cornelius Gross EMBL Monterotondo Developmental Biology

Victor Lamzin EMBL Hamburg

Carsten Schultz Cell Biology & Biophysics

Senior Scientists

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Members of faculty are scientists who lead research groups or the

equivalent: Heads of Unit, group leaders, team

leaders and technical team leaders as well as

visiting scientists in a group leader position.

Many group leaders have joint appointments with other Units to promote

interdisciplinary research and to enhance exchange

of information, tools and techniques.

Faculty on 31 December 2009


Position Primary appointment Secondary appointment

Claude Antony Team Leader Core Facilities Cell Biology & Biophysics

Alexander Aulehla Group Leader Developmental Biology

Orsolya Barabas Group Leader Structural & Computational Biology

Imre Berger Group Leader Grenoble Genome Biology

Paul Bertone Group Leader EMBL-EBI Genome Biology, Developmental Biology

John Briggs Group Leader Structural & Computational Biology

Damian Brunner Group Leader Cell Biology & Biophysics Developmental Biology

Teresa Carlomagno Group Leader Structural & Computational Biology Genome Biology

Florent Cipriani Team Leader Grenoble

Guy Cochrane Team Leader EMBL-EBI

Stefano De Renzis Group Leader Developmental Biology

Anton Enright Group Leader EMBL-EBI

Stefan Fiedler Team Leader Hamburg

Paul Flicek Team Leader EMBL-EBI

Anne-Claude Gavin Group Leader Structural & Computational Biology Genome Biology

Toby Gibson Team Leader Structural & Computational Biology

Darren Gilmour Group Leader Cell Biology & Biophysics Developmental Biology

Christian Häring Group Leader Cell Biology & Biophysics

Darren Hart Team Leader Grenoble

Marcus Heisler Group Leader Developmental Biology

Paul Heppenstall Group Leader Monterotondo

Christoph Hermes Group Leader Hamburg

Henning Hermjakob Team Leader EMBL-EBI

Wolfgang Huber Group Leader Genome Biology EMBL-EBI

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Lars Hufnagel Group Leader Cell Biology & Biophysics Developmental Biology

Sarah Hunter Team Leader EMBL-EBI

Petteri Jokinen Technical Team Leader EMBL-EBI

Marko Kaksonen Group Leader Cell Biology & Biophysics

Paul Kersey Team Leader EMBL-EBI

Gerard Kleywegt Team Leader EMBL-EBI

Michael Knop Group Leader Cell Biology & Biophysics

Maja Köhn Group Leader Genome Biology

Jan Korbel Group Leader Genome Biology EMBL-EBI

Jeroen Krijgsveld Team Leader Genome Biology

Andreas Ladurner Group Leader Genome Biology Structural & Computational Biology

Nicolas Le Novère Group Leader EMBL-EBI Monterotondo

Edward Lemke Group Leader Structural & Computational Biology Cell Biology & Biophysics

Rodrigo Lopez Team Leader EMBL-EBI

Nicholas Luscombe Group Leader EMBL-EBI Genome Biology

José Antonio Márquez Team Leader Grenoble

Andrew McCarthy Team Leader Grenoble

Johanna McEntyre Team Leader EMBL-EBI

Rob Meijers Group Leader Hamburg

Wolfram Meyer-Klaucke Team Leader Hamburg

Liliana Minichiello Group Leader Monterotondo Developmental Biology

Juerg Müller Group Leader Genome Biology Developmental Biology

Jochen Müller-Dieckmann

Team Leader Hamburg

François Nédélec Group Leader Cell Biology & Biophysics Structural & Computational Biology

Claus Nerlov Group Leader Monterotondo Genome Biology

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Dónal O’Carroll Group Leader Monterotondo Developmental Biology, Genome Biology

Claire O’Donovan Technical Team Leader EMBL-EBI

John Overington Team Leader EMBL-EBI

Daniel Panne Group Leader Grenoble Genome Biology

Rainer Pepperkok Team Leader Cell Biology & Biophysics Core Facilities

Francesca Peri Group Leader Developmental Biology

Ramesh Pillai Group Leader Grenoble Genome Biology

Dietrich Rebholz-Schuhmann

Group Leader EMBL-EBI

Peter Rice Team Leader EMBL-EBI

Ugis Sarkans Technical Team Leader EMBL-EBI

Christiane Schaffitzel Team Leader Grenoble

Klaus Scheffzek Team Leader Structural & Computational Biology Developmental Biology

Reinhard Schneider Team Leader Structural & Computational Biology

Thomas Schneider Group Leader Hamburg

François Spitz Group Leader Developmental Biology Monterotondo

Christoph Steinbeck Team Leader EMBL-EBI

Ernst Stelzer Group Leader Cell Biology & Biophysics

Peter Stoehr Team Leader EMBL-EBI

Thomas Surrey Group Leader Cell Biology & Biophysics

Dmitri Svergun Group Leader Hamburg

Mathias Treier Group Leader Developmental Biology Monterotondo

Paul Tucker Group Leader Hamburg

Weimin Zhu Technical Team Leader EMBL-EBI

Intellectual Property

CATEGORIES OF STAFF




exceptional cases.

Predoctoral and postdoctoral fellows:

They receive stipends either from EMBL or from

external institutions.






19

In 2009, 37 invention disclosures were submitted as follows: Cell Biology and Cell Biophysics (7), Developmental Biology (6), Genome Biology (5), Structural and Computational Biology (11), Core Facilities (3), Additional Research Activities (2), Interdisciplinary (3).

8 patent applications were applied for in 2009 with the following breakdown according to Research Programmes: Cell Biology and Cell Biophysics (2), Structural and Computational Biology (2), Genome Biology (1), Interdisciplinary (3).

Additionally, 2 software inventions were protected by copyrights during 2009.

10 patents were granted during the period.

Granted patents in 2009Patent number Title Granting date Inventors

CN ZL00812739,5Methods and compositions for directed cloning and subcloning using homologous recombination

18.03.2009 Francis Stewart, Youming Zhang, Joep Pieter Muyers

AU 2003227873 Method for producing monoclonal antibodies 26.03.2009 Alan Sawyer, Wilhelm Ansorge, Frederico De Masi, Heike Wilhelm

JP 4312981Methods and compositions for directed cloning and subcloning using homologous recombination


IN 235338Methods and compositions for directed cloning and subcloning using homologous recombination


US 7,554,725Microscope with a viewing direction perpendicular to the illumination direction

30.06.2009Ernst Stelzer, Jan Huisken, Steffen Lindeck, Sebastian Enders, James Swoger

KR 10-0909681 RNA interference mediating small RNA molecules 21.07.2009Thomas Tuschl, Sayda Elbashir, Winfried Lendeckel, Matthias Wilm, Reinhard Lührmann

CN 01820900.9 RNA interference mediating small RNA molecules 05.08.2009Thomas Tuschl, Sayda Elbashir, Winfried Lendeckel, Matthias Wilm, Reinhard Lührmann

EP 1 291 420 Novel DNA cloning method 25.11.2009 Francis Stewart, Youming Zhang, Frank Buchholz

JP 4429736 Method for producing monoclonal antibodies 25.12.2009 Alan Sawyer, Wilhelm Ansorge, Frederico De Masi, Heike Wilhelm

SG 130419 Method for determining protein solubility 31.12.2009 Darren Hart

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EMBL International PhD Programme

PhD theses 2009Founded in 1983, the EMBL International PhD Programme has established itself as a reference in international graduate education in the life sciences and is a centrepiece of EMBL’s training activities. In 2009, the student body comprised 192 students from 34 countries.

In 2009, the following students defended their theses:

Boris Bryk TOR signaling: from FRET probes development to function of MAP4K3 in Drosophila Ruprecht-Karls-University of Heidelberg and EMBL

Gülcin Cakan AkdoganFGF signaling couples morphogenesis to collective cell migration in the zebrafish posterior lateral line primordium

Ruprecht-Karls-University of Heidelberg and EMBL

Catarina Machado de Oliveira Catela

Signaling the heart: novel roles for the P13-kinase and FGF cascades in cardiac development


Iryna Charapitsa Zhloba Biochemical and functional characterization of the novel Non Specific Lethal complex Ruprecht-Karls-University of Heidelberg and EMBL

Claudia Chica Eliciting information from protein sequences: a lesson from linear motif conservation Ruprecht-Karls-University of Heidelberg and EMBL

Foteini Christodoulou Animal microRNAs and the evolution of tissue identity University of Crete and EMBL

Marcello ClericiStructural insights on the interaction of Nonsense-Mediated mRNA Decay proteins UPF1 and UPF2

University of Grenoble and EMBL

Amanda Cobos Correa Design, synthesis and application of fluorescent tools to study MMP12 activity Ruprecht-Karls-University of Heidelberg and EMBL

Anne DueStructural, functional and evolutionary insights into the promiscuous enzyme Phosphoribosyl Isomerase A

University of Copenhagen

Elisa Dultz Nuclear pore complex assembly in interphase and mitosis Ruprecht-Karls-University of Heidelberg and EMBL

Malgorzata Duszczyk Structural studies on Xist RNA in X-inactivation University of Nijmegen and EMBL

Tobias Eisenberger Proteomic and genomic analysis of Sall4 function Ruprecht-Karls-University of Heidelberg and EMBL

Shih-Jung Fan Drosophila Ge-1 is an essential P-body component involved in oskar mRNA localization Ruprecht-Karls-University of Heidelberg and EMBL

Tiago FerreiraSerotonin 1A receptor functions during development to refine the dendritic arbor of principal hippocampal neurons


Konrad FoerstnerComputational analysis of metagenomic data: delineation of compositional features and screens for desirable enzymes

Würzburg University

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EMBL International PhD Programme cont.

Adriana GambardellaA CREB-C/EBPb cascade induce M2 macrophage-specific gene expression and promotes resolution of inflammation

University of Milano and EMBL

Christian Hentrich The role of antagonistic mitotic kinesins in microtubule self-organization Ruprecht-Karls-University of Heidelberg and EMBL

Abdullah KahramanThe geometry and physicochemistry of protein binding sites and ligands and their detection in electron density maps

University of Cambridge

Rozina Kardakaris Macrophage and endothelial-specific Role of p38a MAPK in atherosclerosis Ruprecht-Karls-University of Heidelberg and EMBL

Aynur Kaya Copur Analysis of force generation and MT re-organization during dorsal closure Ruprecht-Karls-University of Heidelberg and EMBL

Philipp KellerIn toto reconstruction of zebrafish embryonic development by scanned light sheet microscopy and analysis of the evolution of mutational robustness in the yeast genome architecture


Nicola Kerrison Transcriptome analysis of longevity in mice University of Cambridge

Uros Krzic Multiple-view microscopy with light-sheet based fluorescence microscope Ruprecht-Karls-University of Heidelberg

Michael KuhnIntegrating chemical and protein interactions: From interaction networks to human phenotypes


Styliani Lamprinaki Studying splicing and the formation of mRNPs Ruprecht-Karls-University of Heidelberg and EMBL

Esther LenherrExploring the main architecture and the catalytic mechanisms of neurofibromin, the vacuolar transporter chaperone protein Vtc4p and the plant glutamate cysteine ligase


Ya-Hsin LiuA systematic analysis of Tinman function reveals Eya and JAK-STAT signaling as essential regulators of muscle development


Eugenio Mancera Ramos High-resolution mapping of meiotic recombination in the yeast genome Ruprecht-Karls-University of Heidelberg and EMBL

Elena ManciniHematopoietic stem cells and their transcription factor network: regulation in normal and aberrant hematopoiesis


Alison Meynert Function and evolution of regulatory elements in vertebrates University of Cambridge

Michael MüllerIntegrated analysis of proteomics data to assess and improve the scope of mass spectrometry based genome annotation


Gabriele MusumeciTrkB receptor: differential modulation of fear learning through different phosphorylation sites. An insight in the different roles played by the PLCg and Shc docking sites on TrkB and a proteomic approach


Kevin NagelAutomatic functional annotation of predicted active sites: combining PDB and literature mining


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EMBL International PhD Programme cont.

Agnieszka NowakStructural studies of D. melanogaster Nurf55 protein: histone chaperone and subunit of the Polycomb Repressive Complex 2


Evangelos PafilisWeb-based named entity recognition and data integration to accelerate molecular biology research


Fabio Pardi Algorithms on phylogenetic trees University of Cambridge

Georgios Pavlopoulos Data integration and visualization techniques in systems biology Ruprecht-Karls-University of Heidelberg and EMBL

Evangelia Petsalaki Prediction of peptide-protein interactions and their structures Ruprecht-Karls-University of Heidelberg and EMBL

Christian Poulsen CFP-10/ESAT-6 complex WXG100 proteins Type VII and VIIb secretion systems University of Aarhus

Sergey PrykhozhijThe role of Sonic Hedgehog in regulating proliferation, cell survival, and cell-cycle exit in the zebrafish fin buds and neural-plate derived tissues


Aswin Sai Narain Seshasayee A computational study of bacterial gene regulation and adaptation on a genomic scale University of Cambridge

Julianna SolomonsStructural and functional studies of AMSH, implicated in the Endosomal Sorting Pathway and Enveloped Virus Budding


Melanie Stefan On the function of calcium-regulated allosteric devices in synaptic plasticity University of Cambridge

Carolina TängemoDevelopment and application of an approach to study Golgi complex de novo biogenesis in mammalian cells after complete organelle removal


Lieve Temmerman Insulin-like Growth Factor 1 isoforms in the central nervous system KU Leuven and EMBL

Dominic TölleInvestigating the functional consequences of glutamate receptor diffusion using single-particle modelling approaches


Guillaume Valentin Chemokine receptors orchestrate collective cell migration in the zebrafish lateral line University of Montpellier 2

Raquel Vidal Matos Biochemical characterization of the Drosophila polycomb protein DSFMBT Ruprecht-Karls-University of Heidelberg and EMBL

Holger von MoellerStructural and biochemical studies of the DEAD-box Helicase Dbp5 and nucleoporin Nup214 Involved in mRNA export

Ludwig-Maximilians Universiät München and EMBL

Rudolf Walczak The role of MEL-28 in nuclear pore complex formation Ruprecht-Karls-University of Heidelberg and EMBL

Emine Sevil Yavuz Interplay between the transmembrane nucleoporin Pom121 and the Ran GTPase system Ruprecht-Karls-University of Heidelberg and EMBL

Hayretin YumerefendiStructural characterisation of human kinases using a library-based construct screening approach


Daniel Zerbino Assembling and comparing genomes using de Bruijn graphs University of Cambridge

23

Types of eventsEMBL’s conferences and workshops combine talks with scientific poster sessions to facilitate knowledge exchange. Conferences attract around 300 participants, while workshops cater for about 120.

Courses focus on practical experiments combined with talks on a specific scientific topic. Due to their hands-on nature, they have 15-20 participants.

EMBL-EBI offers modular training to its database users.

Other events which attract outside participants include Science and Society lectures and symposia, LearningLABs for teachers organised by the European Learning Laboratory for the Life Sciences (ELLS) and outreach events organised by the Office of Information and Public Affairs (OIPA; visits from schools, Girls’ Day, etc).

Events in 2009

The number of courses and conferences at the five EMBL sites in 2009 were as follows:

EMBL Heidelberg: 28 (2,341 participants)

EMBL-EBI: 27

EMBL Grenoble: 1

EMBL Hamburg: 3

EMBL Monterotondo: 1

For a wider audience including members of the public, teachers and students, the following events took place in 2009:

Science and Society: 14 (12 lectures, one conference, one symposium)

ELLS: 5 (ca.100 participants)

Other (outreach events organised by OIPA, school visits etc): 18 (ca. 350 participants)

Events

24

External collaborations are joint research projects between EMBL group leaders or group members and at least one external institution or collaborator. They offer the opportunity to conduct interdisciplinary research and to benefit from a broad spectrum of scientific know-how and technical expertise.

In 2009, there were 795 ongoing collaborations at EMBL, 84 of which led to publications. Click here for a PDF of these publications.

Collaborations

1

External collaborations leading to 83 publications in 2009

Antony Team

• Spindle organisation in budding yeast T. Tomoyuki Tanaka, University of Dundee, United Kingdom

• Xenopus spindle reconstruction by electron tomography R. Heald, University of California, Berkeley CA, USA

Berger Group

• Membrane Protein Translocation and Folding I. Collinson, University of Bristol, United Kingdom

Cipriani Team

• Crystal dehydration M. Bowler, ESRF Grenoble, France M. Walsh, MRC, London, United Kingdom

Cusack Group

• Influenza virus polymerase R. Ruigrok, IVMS, Grenoble, France J. Ortin, CSIC, Madrid, Spain

Electron Microscopy Core Facility

• Denge virus replication and assembly sites R. Bartenschlager, University of Heidelberg, Germany

Ephrussi Group

• J. Kraus and Chr. Nüsslein-Volhard, Max-Planck-Institut für Entwicklungsbiologie Tübingen, Germany

Gibson Team

• Gene Expression in Cancer K. O. Greulich, Jena, Germany

• Ataxia protein architecture A. Pastore, NIMR Mill Hill, London, United Kingdom

• ELM - The Eukaryotic Linear Motif Resource R. Aasland, Bergen University, Bergen, Norway

http://www.embl.de/aboutus/communication_outreach/publications/facts_figures/pdf/10_collaborations_2009.pdf

Heidelberg•Hinxton•Grenoble•Hamburg•Monterotondo

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Facts and Figures