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8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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About Science Prof OnlinePowerPoint Resources
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From the Virtual Cell Biology Classroomon ScienceProfOnline.com Image: Compound microscope objectives, T. Port
Tami Port, MSCreator of Science Prof OnlineChief Executive NerdScience Prof OnlineOnline Education Resources, LLC
http://www.scienceprofonline.org/http://creativecommons.org/licenses/by-sa/3.0/http://creativecommons.org/licenses/by-sa/3.0/http://creativecommons.org/licenses/by-sa/3.0/http://creativecommons.org/licenses/by-sa/3.0/mailto:[email protected]://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/mailto:[email protected]:[email protected]://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlmailto:[email protected]://creativecommons.org/licenses/by-sa/3.0/http://creativecommons.org/licenses/by-sa/3.0/http://creativecommons.org/licenses/by-sa/3.0/http://www.scienceprofonline.org/8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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Metabolism
Catabolism
of Proteins
& Fats
Image: Hummusby Paul GoyetteFrom the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://en.wikipedia.org/wiki/File:Hummus_from_The_Nile.jpghttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://en.wikipedia.org/wiki/File:Hummus_from_The_Nile.jpg8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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Catabolism of Proteins & Fats
Q:So far, in
our study of
metabolism,what hasprovided theenergy used tomake ATP?
Images: Sugar, T. PortFrom the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://www.scienceprofonline.com/chemistry/what-is-nucleotide-adenosine-triphosphate-atp.htmlhttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/chemistry/what-is-nucleotide-adenosine-triphosphate-atp.html8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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Catabolism of Proteins & Fats
How do we metabolize thingsthat arent glucose?
Fats, proteinsand carbscan all
provide energy for the cell.
Basic pathways used to extractenergy from fat & protein arethe same as for carbs:
glycolysis, Krebs, ETCbutthere are some extra steps.
Images: Olive Oil, Alex Ex; Raw beef, MCBFrom the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://www.scienceprofonline.com/chemistry/what-is-a-lipid-organic-chemistry-fats-phospholipids-waxes-steroids.htmlhttp://www.scienceprofonline.org/chemistry/what-are-proteins-amino-acids-peptide-bonds.htmlhttp://www.scienceprofonline.org/chemistry/organic-chemistry-what-is-a-carbohydrate.htmlhttp://www.scienceprofonline.org/metabolism/electron-transport-chain-cellular-respiration.htmlhttp://www.scienceprofonline.org/metabolism/electron-transport-chain-cellular-respiration.htmlhttp://en.wikipedia.org/wiki/File:Italian_olive_oil_2007.jpghttp://en.wikipedia.org/wiki/File:Standing-rib-roast-MCB.jpghttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://en.wikipedia.org/wiki/File:Standing-rib-roast-MCB.jpghttp://en.wikipedia.org/wiki/File:Italian_olive_oil_2007.jpghttp://www.scienceprofonline.org/metabolism/electron-transport-chain-cellular-respiration.htmlhttp://www.scienceprofonline.org/chemistry/organic-chemistry-what-is-a-carbohydrate.htmlhttp://www.scienceprofonline.org/chemistry/what-are-proteins-amino-acids-peptide-bonds.htmlhttp://www.scienceprofonline.com/chemistry/what-is-a-lipid-organic-chemistry-fats-phospholipids-waxes-steroids.html8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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Organic Molecules -Proteins
Dehydration synthesis is the chemical reaction that joins amino acids into polypeptide.
Q: What reaction breaks down polypeptides into amino acids?
From the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://www.scienceprofonline.org/chemistry/what-are-proteins-amino-acids-peptide-bonds.htmlhttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.org/chemistry/what-are-proteins-amino-acids-peptide-bonds.html8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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Protein Catabolism
Image: Protein catabolism, BoumphreyfrFrom the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://commons.wikimedia.org/wiki/File:Protein_catabolism.pnghttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://commons.wikimedia.org/wiki/File:Protein_catabolism.png8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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.
How do we metabolize protein?
Excess amino acidscan be used to synthesize pyruvate, acetyl CoA, and ketogluterate, which
enters the Krebs cycle.
From the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://www.scienceprofonline.org/chemistry/what-are-proteins-amino-acids-peptide-bonds.htmlhttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.org/chemistry/what-are-proteins-amino-acids-peptide-bonds.html8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
8/18Image: Cellular Respiration, Regis Frey
How do we metabolize protein?
Excess amino acids can be used to synthesize pyruvate, acetyl CoA, and ketogluterate, whichenters the Krebs cycle.
From the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://en.wikipedia.org/wiki/File:CellRespiration.svghttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://en.wikipedia.org/wiki/File:CellRespiration.svg8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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How do we metabolize fats?
Q:Fats and oils are made fromwhich two kinds of molecules?
Before these fats can be
broken down to releaseenergy, they must beconverted to smaller units.
The first step is to break thebonds between the glyceroland the fatty acids.
From the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://www.scienceprofonline.com/chemistry/what-is-a-lipid-organic-chemistry-fats-phospholipids-waxes-steroids.htmlhttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/chemistry/what-is-a-lipid-organic-chemistry-fats-phospholipids-waxes-steroids.html8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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How do we metabolize fats?
Glycerol is a 3-carbon moleculethat is converted intoglyceraldehyde-3-phosphate.
Because glyceraldehyde-3-phosphate is involved in one ofthe steps in glycolysis, it can
enter the glycolysis pathway.
From the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.html8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
11/18Image: Glycolysis, Regis Frey
How do we metabolize fats?
From the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://en.wikipedia.org/wiki/File:CellRespiration.svghttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://en.wikipedia.org/wiki/File:CellRespiration.svg8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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These long molecules (typically 14 to 20 carbons long) must also be processed beforethey can be further metabolized.
1. Enter the mitochondrion, where each long chain of carbons that makes up thecarbon skeleton is hydrolyzed (split by the addition of a water molecule) into 2-carbon fragments.
2. Each of the 2-carbon fragments is converted into acetyl. Coenzyme A is added tothe acetyl, and the ____________ goes into _______ ______.
C C
How do we metabolize fatty acid tails?
From the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.html8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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Krebs Cycle(a.k.a Citric Acid Cycle)
How do we metabolize fatty acid tails?
Acetyl-CoA--
Image: Cellular Respiration, Regis FreyFrom the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://en.wikipedia.org/wiki/File:CellRespiration.svghttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://en.wikipedia.org/wiki/File:CellRespiration.svg8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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.
How do we metabolize fats?
From the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://www.scienceprofonline.com/chemistry/what-is-a-lipid-organic-chemistry-fats-phospholipids-waxes-steroids.htmlhttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/chemistry/what-is-a-lipid-organic-chemistry-fats-phospholipids-waxes-steroids.html8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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Metabolic Processes Bottom Line
Every cell acquires __________.
Metabolism requires energy from_______ or from ___________ of
nutrients.
Energy is ultimately converted to_____ .
is used to do cellular work.ATP
Image: Jumping rope, Meagan E. KleinFrom the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://en.wikipedia.org/wiki/File:Jumprope_navy.jpghttp://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://en.wikipedia.org/wiki/File:Jumprope_navy.jpg8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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Confused?Here are links to fun resources that further explain
cellular respiration:
Metabolism of Proteins & Fats Main Pageon the VirtualCell Biology Classroom ofScience Prof Online.
Cellular Respirationanimation by Jay Phelan, What is Life? AGuide to Biology, W. H. Freeman & Co.
Break It Down Againmusic video by Tears for Fears.
How NAD+ Worksanimation and quiz from McGraw-Hill.
Glycolysisanimation and quiz from McGraw-Hill.
Kreb Cycle Animation & Quiz 1from McGraw-Hill.
Kreb Cycle Animation & Quiz 2from McGraw-Hill.
Electron Transport Chainanimation from Molecular & CellularBiology Learning Center.
Food Moleculesvideo from HowStuffWorks, a Discovery company.
The Protein Songridiculous but funny song by Ruan0
Grease (Is the Word) sung by Frankie Valli.
(You must be in PPT slideshow view to click on links.)
From the Virtual Cell Biology Classroomon ScienceProfOnline.com
http://www.scienceprofonline.com/vcbc/catabolism-proteins-fats-main.htmlhttp://www.scienceprofonline.com/http://www.sumanasinc.com/webcontent/animations/content/cellularrespiration.htmlhttp://www.youtube.com/watch?v=VzNvpHxWO8chttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_nad__works.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_glycolysis_works.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_1_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_2_.htmlhttp://vcell.ndsu.edu/animations/etc/index.htmhttp://videos.howstuffworks.com/discovery/29544-assignment-discovery-food-molecules-video.htmhttp://www.youtube.com/watch?v=qXzE74Kw_Fwhttp://www.youtube.com/watch?v=sGoiVgbpJz8http://www.youtube.com/watch?v=sGoiVgbpJz8http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/http://www.scienceprofonline.com/virtual-cell-main.htmlhttp://www.youtube.com/watch?v=sGoiVgbpJz8http://www.youtube.com/watch?v=sGoiVgbpJz8http://www.youtube.com/watch?v=qXzE74Kw_Fwhttp://videos.howstuffworks.com/discovery/29544-assignment-discovery-food-molecules-video.htmhttp://vcell.ndsu.edu/animations/etc/index.htmhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_2_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_2_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_2_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_1_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_1_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_krebs_cycle_works__quiz_1_.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_glycolysis_works.htmlhttp://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_the_nad__works.htmlhttp://www.youtube.com/watch?v=VzNvpHxWO8chttp://www.sumanasinc.com/webcontent/animations/content/cellularrespiration.htmlhttp://www.scienceprofonline.com/http://www.scienceprofonline.com/vcbc/catabolism-proteins-fats-main.htmlhttp://www.cst.cmich.edu/users/schul1te/animations/fermentation.swf8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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Assignment
At the end of somelectures, I will give yousome type of in-classassignment orhomework to evaluate
your understanding oftodays topic.
This assignment willalways be open-book.
Today, if assigned youwill be completing anessay questionon thetopic of Catabolism ofProteins & Fats.
From the Virtual Cell Biology Classroom on ScienceProfOnline.com
See the ScienceProfOnlineVirtual Cell BiologyClassroom: Metabolism of Fats & Proteinsfor a
printable Word .doc of this assignment.
Image: Hummusby Paul Goyette
http://www.scienceprofonline.com/http://www.scienceprofonline.com/http://en.wikipedia.org/wiki/File:Hummus_from_The_Nile.jpghttp://en.wikipedia.org/wiki/File:Hummus_from_The_Nile.jpghttp://www.scienceprofonline.com/http://www.scienceprofonline.com/8/13/2019 Fat Protein Metabolism Biology Lecture PowerPoint VCBC
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Are you feeling blinded by science?
Do yourself a favor. Use the
Virtual Cell BiologyClassroom (VCBC) !
The VCBC is full of resources to help you succeed,including:
practice test questions
review questions
study guides and learning objectives PowerPoints on other topics
You can access the VCBC by going to the Science Prof Online websitewww.ScienceProfOnline.com
I Bli d d With S i lb Th D lb E d b t M i R i Wiki
http://www.scienceprofonline.org/virtual-cell-main.htmlhttp://www.scienceprofonline.com/http://www.youtube.com/watch?v=2IlHgbOWj4ohttp://en.wikipedia.org/wiki/File:Endomembrane_system_diagram_en.svghttp://en.wikipedia.org/wiki/File:Endomembrane_system_diagram_en.svghttp://www.youtube.com/watch?v=2IlHgbOWj4ohttp://www.scienceprofonline.com/http://www.scienceprofonline.org/virtual-cell-main.html