Fear Conditioning - TSE Systemsdownload.tse-systems.com/TSE_FCS_mouse_Publications.pdf · Last updated November 2014 [email protected] Publications for Fear Conditioning System

Fear Conditioning Mouse

www.TSE-Systems.com [email protected]

http://www.tse-systems.com/


www.TSE-Systems.com Last updated November 2014 [email protected]

Publications for Fear Conditioning System - MOUSE

2014

Seo J, Giusti-Rodríguez P, Zhou Y, Rudenko A, Cho S, Ota KT, Park C, Patzke H, Madabhushi

R, Pan L, Mungenast AE, Guan JS, Delalle I, Tsai LH. Activity-dependent p25 generation

regulates synaptic plasticity and Aβ-induced cognitive impairment. Cell 2014; 157(2):486-98

http://www.ncbi.nlm.nih.gov/pubmed/24725413

2013

Albrecht A, Thiere M, Bergado-Acosta JR, Poranzke J, Müller B, Stork O. Circadian

Modulation of Anxiety: A Role for Somatostatin in the Amygdala. PLoS One 2013;

8(12):e84668


Contestabile A, Greco B, Ghezzi D, Tucci V, Benfenati F, Gasparini L. Lithium rescues

synaptic plasticity and memory in Down syndrome mice. J Clin Invest 2013; 123(1):348-61


Corcoran KA, Leaderbrand K, Radulovic J. Extinction of remotely acquired fear depends on

an inhibitory NR2B/PKA pathway in the retrosplenial cortex. J Neurosci 2013; 33(50):19492-8


Govindarajan N, Rao P, Burkhardt S, Sananbenesi F, Schlüter OM, Bradke F, Lu J, Fischer A.

Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease.

EMBO Mol Med 2013; 5(1):52-63


Gräff J, Kahn M, Samiei A, Gao J, Ota KT, Rei D, Tsai LH. A dietary regimen of caloric

restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration. J

Neurosci 2013; 33(21):8951-60


Guzmán YF, Tronson NC, Jovasevic V, Sato K, Guedea AL, Mizukami H, Nishimori

K, Radulovic J. Fear-enhancing effects of septal oxytocin receptors. Nat Neurosci 2013;

16(9):1185-7


Haaker J, Gaburro S, Sah A, Gartmann N, Lonsdorf TB, Meier K, Singewald N, Pape HC,

Morellini F, Kalisch R. Single dose of L-dopa makes extinction memories context-

independent and prevents the return of fear. PNAS 2013; 110(26):E2428-36


Hohmann CF, Hodges A, Beard N, Aneni J. Effects of brief stress exposure during early

postnatal development in balb/CByJ mice: I. Behavioral characterization. Dev Psychobiol

2013; 55(3):283-93


Kerimoglu C, Agis-Balboa RC, Kranz A, Stilling R, Bahari-Javan S, Benito-Garagorri E, Halder

R, Burkhardt S, Stewart AF, Fischer A. Histone-methyltransferase MLL2 (KMT2B)

is required for memory formation in mice. J Neurosci 2013; 33(8):3452-64













Kulesskaya N, Võikar V, Peltola M, Yegutkin GG, Salmi M, Jalkanen S, Rauvala H. CD73 is a

major regulator of adenosinergic signalling in mouse brain. PLoS One 2013; 8(6):e66896


Macpherson K, Whittle N, Camp M, Gunduz-Cinar O, Singewald N, Holmes A. Temporal

factors in the extinction of fear in inbred mouse strains differing in extinction efficacy. Biol

Mood Anxiety Disord 2013; 3(1):13


Pitts MW, Reeves MA, Hashimoto AC, Ogawa A, Kremer P, Seale LA, Berry MJ. Deletion of

selenoprotein M leads to obesity without cognitive deficits. J Biol Chem 2013;

288(36):26121-34


Rattray I, Smith EJ, Crum WR, Walker TA, Gale R, Bates GP, Modo M. Correlations of

behavioral deficits with brain pathology assessed through longitudinal MRI and

histopathology in the R6/1 mouse model of Huntington's disease. PLoS One 2013;

8(12):e84726


Ufartes R, Schneider T, Mortensen LS, de Juan Romero C, Hentrich K, Knoetgen H, Beilinson

V, Moebius W, Tarabykin V, Alves F, Pardo LA, Rawlins JN,Stuehmer W. Behavioural and

functional characterization of Kv10.1 (Eag1) knockout mice. Hum Mol Genet 2013;

22(11):2247-62


Voikar V, Kulesskaya N, Laakso T, Lauren J, Strittmatter SM, Airaksinen MS. LRRTM1-

deficient mice show a rare phenotype of avoiding small enclosures--a tentative mouse model

for claustrophobia-like behavior. Behav Brain Res 2013; 238:69-78


Youn J, Hager T, Misane I, Pieneman AW, Jansen RF, Ogren SO, Meyer M, Stiedl O. Central

5-HT1A receptor-mediated modulation of heart rate dynamics and its adjustment by

conditioned and unconditioned fear in mice. Br J Pharmacol 2013; 170(4):859-70


Zhang X, Hernandez I, Rei D, Mair W, Laha JK, Cornwell ME, Cuny GD, Tsai LH, Steen JA,

Kosik KS. Diaminothiazoles modify tau phosphorylation and improve the tauopathy in mouse

models. J Biol Chem 2013; 288(30):22042-56


2012

Bahari-Javan S, Maddalena A, Kerimoglu C, Wittnam J, Held T, Bähr M, Burkhardt S, Delalle

I, Kügler S, Fischer A, Sananbenesi F. HDAC1 regulates fear extinction in mice. J Neurosci

2012; 32(15): 5062-73


Chaperon F, Fendt M, Kelly PH, Lingenhoehl K, Mosbacher J, Olpe HR, Schmid P, Sturchler

C, McAllister KH, van der Putten PH, Gee CE. Gastrin-releasing Peptide signaling plays a

limited and subtle role in amygdala physiology and aversive memory. PLoS One 2012;

7(4):e34963














Cooper A, Grigoryan G, Guy-David L, Tsoory MM, Chen A, Reuveny E. Trisomy of the G

protein-coupled K+ channel gene, Kcnj6, affects reward mechanisms, cognitive functions, and

synaptic plasticity in mice. Proc Natl Acad Sci USA 2012; 109(7):2642-7


Morawska MM, Fendt M. The effects of muscimol and AMN082 injections into

the medial prefrontal cortex on the expression and extinction of conditioned fear in mice. J

Exp Biol 2012; 215(Pt8):1394-8


Pitts MW, Raman AV, Hashimoto AC, Todorovic C, Nichols RA, Berry MJ. Deletion of

selenoprotein P results in impaired function of parvalbumin interneurons and alterations in f

ear learning and sensorimotor gating. Neuroscience 2012; 208:58-68


Schell H, Boden C, Chagas AM, Kahle PJ. Impaired c-Fos and polo-like kinase 2 induction in

the limbic system of fear-conditioned α-synuclein transgenic mice. PloS One 2012;

7(11):e50245


Toth I, Neumann ID, Slattery DA. Social fear conditioning: a novel and specific animal model

to study social anxiety disorder. Neuropsychopharmacology 2012; 37:1433-43


2011

Agis- Balboa RC, Arcos- Diaz D, Wittnam J, Govindarajan N, Blom K, Burkhardt S,

Haladyniak U, Agbemenyah HY, Zovoilis A, Salinas- Riester G, Opitz L, Sananbenesi F.,

Fischer A. A hippocampal insulin- growth factor 2 pathway regulates the extinction of fear

memories. EMBO J 2011; 30:4071-83


Corcoran KA, Donnan MD, Tronson NC, Guzmán YF, Gao C, Jovasevic V, Guedea AL,

Radulovic J. NMDA receptors in retrosplenial cortex are necessary for retrieval of recent and

remote context fear memory. J Neurosci 2011; 31(32):11655-9


Gao C, Frausto SF, Guedea AL, Tronson NC, Jovasevic V, Leaderbrand K, Corcoran KA,

Guzmán YF, Swanson GT, Radulovic J. IQGAP1 regulates NR2A signaling, spine density, and

cognitive processes. J Neurosci 2011; 31(23):8533-42


Kamprath K, Romo-Parra H, Häring M, Gaburro S, Döngi M, Lutz B, Pape HC. Short-term

adaption of conditioned fear responses through endocannabinoid signaling in the central

amygdala. Neuropsychopharmacology 2011; 36(3):652-63


Kulesskaya N, Rauvala H, Voikar V. Evaluation of social an physical enrichment in

modulation of behavioural phenotype in C57BL/6J female mice. PLoS One 2011; 6(9):e14755















Lesting J, Geiger M, Narayanan RT, Pape HC, Seidenbecher T. Impaired extinction of fear

and maintained amygdala-hippocampal theta synchrony in a mouse model of temporal lobe

epilepsy. Epilepsia 2011;52(2):337-46


Lesting J, Narayanan RT, Kluge C, Sangha S, Seidenbecher T, Pape H-C. Patterns of coupled

theta activity in amygdala -hippocampal- prefrontal cortical circuits during fear extinction.

PLoS One 2011; 6(6):e21714


Rao-Ruiz P, Rotaru DC, van der Loo RJ, Mansvelder HD, Stiedl O, Smit AB, Spijker S.

Retrieval-specific endocytosis of GluA2-AMPARs underlies adaptive reconsolidation of

contextual fear. Nat Neurosci 2011; 14(10):1302-8


Sartori SB, Hauschild M, Bunck M, Gaburro S, Landgraf R, Singewald N. Enhanced fear

expression in a psychopathological mouse model of trait anxiety: pharmacological

interventions. PLoS One 2011; 6(2):e16849


Schilling S, Kohlmann S, Bäuscher C, Sedlmeier R, Koch B, Eichentopf R, Becker A, Cynis H,

Hoffmann T, Berg S, Freyse J, von Hörsten S, Rossner S, Graubner S, Demuth HU. Glutaminyl

cyclase (OC) knok out mice show mild hypothyreodism but absence of hypogonadism:

implications for enzyme function and drug development. J Biol Chem 2011; 286(16):1-19

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077621/

Skórzewska A, Lehner M, Hamed A, Wisłowska- Stanek A, Turzyńska D, Soboleska A,

Płaźnik A. The effect of CRF2 receptor antagonists on rat conditioned fear responses and c-

Fos and CRF expression in the brain limbic structures. Behav Brain Res 2011; 221(1):155-65


Vetere G, Marchetti C, Benevento M, Tafi E, Marie H, Ammassari- Teule M. Viral-mediated

expression of a constitutively active from CREB in the dentate gyrus does not induce

abnormally enduring fear memory. Behav Brain Res 2011; 222(2):394-6


Vetere G, Marchetti C, Benevento M, Tafi E, Marie H, Ammassari-Teule M. Viral-mediated

expression of a constitutively active form of CREB in the dentate gyrus does not induce

abnormally enduring fear memory. Behav Brain Res 2011; 222(2):394-6


2010

Albrecht A, Bergado-Acosta JR, Pape HC, Stork O. Role of the neural cell adhesion molecule

(NCAM) in amygdalo-hippocampal interactions and salience determination of contextual fear

memory. Int J Neuropsychopharmacol 2010; 13:661-74


Klein S, Nicolas LB, Lopez-Lopez C, Jacobson LH, McArthur SG, Grundschober C, Prinssen EP.

Examining face and construct validity of a noninvasive model of panic disorder in Lister-

hooded rats. Psychopharmacology 2010; 211(2):197-208














Kuczera T, Stilling RM, Hsia HE, Bahari-Javan S, Irniger S, Nasmyth K, Sananbenesi F, Fischer

A. The anaphase promoting complex is required for memory function in mice. Learn Mem

2010; 18(1):49-57


Lehner M, Wislowska-Stanek A, Maciejak P, Szyndler J, Sobolewska A, Krza´scik P, Pla´znik

A. The relationship between pain sensitivity and conditioned fear response in rats. Acta

Neurobiol Exp 2010; 70:56-66


Neufeld-Cohen A, Tsoory MM, Evans AK, Getselter D, Gil S, Lowry CA, Vale WW, Chen A. A

triple urocortin knockout mouse model reveals an essential role for urocortins in stress

recovery. Proc Natl Acad Sci USA 2010; 104(44):19020-5


Regev L, Neufeld-Cohen A, Tsoory M, Kuperman Y, Getselter D, Gil S, Chen A. Prolonged

and site-specific over-expression of corticotropin-releasing factor reveals differential roles for

extended amygdala nuclei in emotional regulation. Mol Psychiatry 2010; 16:714-28


Sherrin T, Blank, T, Hippel C, Rayner M. Hippocampal c-Jun-N-terminal kinases serve as

negative regulators of associative learning. J Neurosci 2010; 30(40):13348-61


2009

Fendt M, Bürki H, Imobersteg S, Lingenhöhl K, McAllister KH, Orain D, Uzunov DP,

Chaperon F. Fear-reducing effects of intra-amygdala neuropeptide Y infusion in animal

models of conditioned fear: an NPY Y1 receptor independent effect. Psychopharmacology

2009; 206:291-301


Fendt M, Bürki H, Imobersteg S, van der Putten H, McAllister K, Leslie JC, Shaw D, Hölscher

C. The effect of mGlu8 deficiency in animal models of psychiatric diseases. Genes Brain Behav

2009; 9:33-44


Guzmán YF, Tronson NC, Guedea A, Huh KH, Gao C, Radulovic J. Social modeling of

conditioned fear in mice by non-fearful conspecifics. Behav Brain Res 2009; 201(1):173-8


Huh KH, Guzman YF, Tronson NC, Guedea AL, Gao C, Radulovic J. Hippocampal Erk

mechanisms linking prediction error to fear extinction: roles of shock expectancy and

contextual aversive valence. Learn Mem 2009; 16:273-8


Jüngling K, Seidenbecher T, Sosulina L, Lesting J, Sangha S, Clark SD, Okamura N, Duangdao

DM, Xu YL, Reinscheid RK, Pape HC. Neuropeptide s-mediated control of fear expression and

extinction: role of intercalated GABAergic neurons in the amygdala. Neuron 2009; 59(2):298-

310














Luuk H, Plaas M, Raud S, Innos J, Sütt S, Lasner H, Abramov U, Kurrikoff K, Köks S, Vasar E.

Wfs1-deficient mice display impaired behavioural adaption in stressful environment. Behav

Brain Res 2009; 198(2):334-45


Mao R, Page DT, Merzlyak I, Kim C, Tecott LH, Janak PH, Rubenstein JLR, Sur M. Reduced

conditioned fear response in mice that lack Dlx1 and show subtype-specific loss of

interneurons. J Neurodev Disord 2009; 1(3):224-36


Sangha S, Narayanan RT, Bergado-Acosta JR, Stork O, Seidenbecher T, Pape HC. Deficiency

of the 65 kDa isoform of glutamic acid decarboxylase impairs extinction of cued but not

contextual fear memory. J Neurosci 2009; 29(50):15713-20


Schell H, Hasegawa T, Neumann M, Kahle PJ. Nuclear and neuritic distribution of serine-129

phosphorylated alpha-synuclein in transgenic mice. Neuroscience 2009; 160:796-804


Sherrin T, Todorovic C, Zeyda T, Tan CH, Hon PWT, Zhu YZ, Spiess J. Chronic stimulation of

corticotropin-releasing factor receptor 1 enhances the anxiogenic response of the

cholecystokinin system. Mol Psychiatry 2009; 14(3):291-307


Stiedl O, Jansen RF, Pieneman AW, Ögren SO, Meyer M. Assessing aversive emotional states

through the heart rate in mice: Implications for cardiovascular dysregulation in affective

disorders. Neurosci Biobehav Rev 2009; 33:181-90


Tronson NC, Schrick C, Guzman YF, Hwan Huh K, Srivastava DP, Penzes P, Guedea AI, Gao C,

Radulovic J. Segregated Populations of Hippocampal Principal CA1 Neurons Mediating

Conditioning and Extinction of Contextual Fear. J Neurosci 2009; 29(11):3387-94


Youn J, Misane I, Eriksson TM, Millan MJ, Ögren SO, Verhage M, Stiedl O. Bidirectional

modulation of classical fear conditioning in mice by 5-HT-1A receptor ligands with

contrasting intrinsic activities. Neuropharmacology 2009; 57:567-76


2008

Abrari K, Rashidy-Pour A, Semnanian S, Fathollahi Y. Administration of corticosterone after

memory reactivation disrupts subsequent retrieval of a contextual conditioned fear memory:

dependence upon training intensity. Neurobiol Learn Mem 2008; 89:178-84


Bergado-Acosta JR, Sangha S, Narayanan RT, Obata K, Pape HC, Stork O. Critical role of the

65-kDa isoform of glutamic acid decarboxylase in consolidation and gerneralization of

Pavlovian fear memory. Learn Mem 2008; 15:163-71


Bissière S, Plachta N, Hoyer D, McAllister KH, Olpe HR, Grace AA, Cryan JF. The rostral

anterior cingulate cortex modulates the efficiency of amygdala-dependent fear learning. Biol

Psychiatry 2008; 63(9):821-31














Jamain S, Radyushkin K, Hammerschmidt K, Granon S, Boretius S, Varoqueaux F,

Ramanantsoa N, Gallego J, Ronnenberg A, Winter D, Frahm J, Fischer J, Bourgeron T,

Ehrenreich H, Brose N. Reduced social interaction and ultrasonic communication in a mouse

model of monogenic heritable autism. Proc Natl Acad Sci USA 2008; 105:1710-5


Jüngling K, Seidenbecher T, Sosulina L, Lesting J, Sangha S, Clark SD, Okamura N, Duangdao

DM, Xu YL, Reinscheid RK, Pape HC. Neuropeptide s-mediated control of fear expression and

extinction: role of intercalated GABAergic neurons in the amygdala. Neuron 2008; 59:298-

310


Kiehl TR, Fischer SE, Ezzat S, Asa SL. Mice lacking the transcription factor Ikaros display

behavioral alterations of an anti-depressive phenotype. Exp Neurol 2008; 211(1):107-14


Kim D, Frank CL, Dobbin MM, Tsunemoto RK, Tu W, Peng PL, Guan JS, Lee BH, Moy LY,

Giusti P, Broodie N, Mazitschek R, Delalle I, Haggarty SJ, Neve RL, Lu Y, Tsai LH.

Deregulation of HDAC1 by p25/Cdk5 in Neurotoxicity. Neuron 2008; 60:803-17


Kluge C, Stoppel C, Szinyei C, Stork O, Pape HC. Role of the somatostatin system in

contextual fear memory and hippocampal synaptic plasticity. Learn Mem 2008; 15:252-60


Lehner M, Taracha E, Skórzewska A, Turzyńska D, Sobolewska A, Maciejak P, szyndler J,

Hamed A, Bidziński A, Wisłowska-Stanek A, Płaźnik A. Expression of c-Fos and CRF in the

brains of rats differing in the strength of a fear response. Behav Brain Res 2008; 188:154-67


Maciejak P, Lehner M, Turzynska D, Szyndler J, Bidzinski A, Taracha E, Sobolewska A,

Walkowiak J, Skorzewska A, Wisłowska A, Hamed A, Plaznik A. The opposite role of

hippocampal mGluR1 in fear conditioning in kindled and non-kindled rats. Brain Res 2008;

1187:184-93


Paul C, Schöberl F, Weinmeister P, Micale V, Wotjak CT, Hofmann F, Kleppisch T. Signaling

through cGMP-dependent protein kinase 1 in the amygdala is critical for auditory-cued fear

memory and long-term potentiation. J Neurosci 2008; 28(52):14202-12


Wislowska-Stanek A, Hamed A, Lehner M, Bidzinski A, Turzynska D, Sobolewska A,

Walkowiak J, Plaznik A. Effects of midazolam and buspirone on in vivo concentration of

amino acids and monoamine metabolites in the rat hippocampus. Pharmacol Rep 2008;

60:209-18


2007

Fischer A, Radulovic M, Schrick C, Sananbenesi F, Godovac-Zimmermann J, Radulovic J.

Hippocampal Mek/Erk signaling mediates extinction of contextual freezing behavior.

Neurobiol Learn Mem 2007; 87(1):149-58














Fischer A, Sananbenesi F, Wang X, Dobbin M, Tsai LH. Recovery of learning and memory is

associated with chromatin remodeling. Nature 2007; 447:178-82


Fullgrabe MW, Vengeliene V, Spanagel R. Influence of age at drinking onset on the alcohol

deprivation effect and stress-induced drinking in female rats. Pharmacol Biochem Behav

2007; 86:320-6


Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, Delalle I, Baur JA,

Sui G, Armour SM, Puigserver P, Sinclair DA, Tsai LH. SIRT1 deacetylase protects against

neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.

EMBO J 2007; 26(13):3169-79


Narayanan RT, Seidenbecher T, Sangha S, Stork O, Pape HC. Theta resynchronization during

reconsolidation of remote contextual fear memory. Neuroreport 2007; 18(2):1107-11


Nicolas LB, Klein S, Prinssen EP. Defensive-like behaviors induced by ultra-sound: further

pharmacological characterization in Lister-hooded rats. Psychopharmacology 2007; 194:243-

52


Pugh PL, Vidgeon-Hart MP, Ashmeade T, Culbert AA, Seymour Z, Perren MJ, Joyce F, Bate

ST, Babin A, Virley DJ, Richardson JC, Upton N, Sunter D. Repeated administration of the

noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates

neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and

presenilin-I mutant transgenes. J Neuroinflammation 2007; 4:8


Sananbenesi F, Fischer A, Wang X, Schrick C, Neve R, Radulovic J, Tsai LH. A hippocampal

Cdk5 pathway regulates extinction of contextual fear. Nat Neurosci 2007; 10(8):1012-9


Stiedl O, Misane I, Koch M, Pattij T, Meyer M, Ogren SO. Activation of the brain 5-HT(2C)

receptors causes hypolocomotion without anxiogenic-like cardiovascular adjustments in

mice. Neuropharmacology 2007; 52(3):949-57


Todorovic C, Radulovic J, Jahn O, Radulovic M, Sherrin T, Hippel C, Spiess J. Differential

activation of CRF receptor subtypes removes stress-induced memory deficit and anxiety. Eur

J Neurosci 2007; 25(11):3385-97


Zienowicz M, Wislowska-Stanek A, Lehner M, Taracha E, Skorzewska A, Bidzinski A,

Turzynska D, Sobolewska A, Walkowiak J, Maciejak P, Szyndler J, Plaznik A. Fluoxetine

attenuates the effects of pentylenetetrazol on rat freezing behavior and c-Fos expression in

the dorsomedial periaqueductal gray. Neurosci Lett 2007; 414:252-6















2006

Siren AL, Radyushkin K, Boretius S, Kammer D, Riechers CC, Natt O, Sargin D, Watanabe T,

Sperling S, Michaelis T, Price J, Meyer B, Frahm J, Ehrenreich H. Global brain atrophy after

unilateral parietal lesion and its prevention by erythropoietin. Brain 2006; 129:480-9


von Bohlen und Halbach O, Zacher C, Gass P, Unsicker K. Age-related alterations in

hippocampal spines and deficiencies in spatial memory in mice. J Neurosci Res 2006; 83:525-

31


Zueger M, Urani A, Chourbaji S, Zacher C, Lipp HP, Albrecht U, Spanagel R, Wolfer DP, Gass

P. mPer1 and mPer2 mutant mice show regular spatial and contextual learning in

standardized tests for hippocampus-dependent learning. J Neural Transm 2006; 113(3):347-

56


2005

Fischer A, Sananbenesi F, Pang PT, Tsai L. Opposing roles of transient and prolonged

expression of p25 in synaptic plasticity and hippocampus-dependent memory. Neuron 2005;

48:825-38


Misane I, Tovote P, Meyer M, Spiess J, Ogren SO, Stiedl O. Time-dependent involvement of

the dorsal hippocampus in trace fear conditioning in mice. Hippocampus 2005; 15(4):418-26


Radyushkin K, Anokhin K, Meyer BI, Jiang Q, Alvarez-Bolado G, Gruss P. Genetic ablation of

the mammillary bodies in the Foxb1 mutant mouse leads to selective deficit of spatial

working memory. Eur J Neurosci 2005; 21:219-29


Raud S, Innos J, Abramov U, Reimets A, Kõks S, Soosaar A, Matsui T, Vasar E. Targeted

invalidation of CCK2 receptor gene induces anxiolytic-like action in light-dark exploration, but

not in fear conditioning test. Psychopharmacology 2005; 181:347-57


Ridder S, Chourbaji S, Hellweg R, Urani A, Zacher C, Schmid W, Zink M, Hortnagl H, Flor H,

Henn FA, Schutz G, Gass P. Mice with genetically altered glucocorticoid receptor expression

show altered sensitivity for stress-induced depressive reactions. J Neurosci 2005;

25(26):6243-50


Stiedl O, Meyer M, Jahn O, Ogren SO, Spiess J. Corticotropin-releasing factor receptor 1 and

central heart rate regulation in mice during expression of conditioned fear. J Pharmacol Exp

Ther 2005; 312:905-16













Tornberg J, Voikar V, Savilahti H, Rauvala H, Airaksinen MS. Behavioural phenotypes of

hypomorphic KCC2-deficient mice. Eur J Neurosci 2005; 21:1327-37


Tovote P, Meyer M, Pilz PKD, Ronnenberg A, Ogren SO, Spiess J, Stiedl O. Dissociation of

temporal dynamics of heart rate and blood pressure responses elicited by conditioned fear

but not acoustic startle. Behav Neurosci 2005; 119(1):55-65


Tovote P, Meyer M, Ronnenberg A, Ogren SO, Spiess J, Stiedl O. Heart rate dynamics and

behavioral responses during acute emotional challenge in corticotropin-releasing factor

receptor 1-deficient and corticotropin-releasing factor-overexpressing mice. Neuroscience

2005; 134(4):1113-22


Voikar V, Polus A, Vasar E, Rauvala H. Long-term individual housing in C57BL/6J and DBA/2

mice: assessment of behavioral consequences. Genes Brain Behav 2005; 4:240-52


Wislowska-Stanek A, Zienowicz M, Lehner M, Taracha E, Bidzinski A, Maciejak P,

Skorzewska A, Szyndler J, Plaznik A. Buspirone attenuates conditioned fear-induced c-Fos

expression in the rat hippocampus. Neurosci Lett 2005; 389:115-20


2004

Ahi J, Radulovic J, Spiess J. The role of hippocampal signaling cascades in consolidation of

fear memory. Behav Brain Res 2004; 149:17-31


Fischer A, Sananbenesi F, Schrick C, Spiess J, Radulovic J. Distinct roles of hippocampal de

novo protein synthesis and actin rearrangement in extinction of contextual fear. J Neurosci

2004; 24(8):1962-6


Stiedl O, Tovote P, Ogren SO, Meyer M. Behavioral and autonomic dynamics during

contextual fear conditioning in mice. Auton Neurosci 2004; 115(1-2):15-27


Stork O, Zhdanov AV, Kudersky A, Yoshikawa T, Obata K, Pape HC. Neuronal functions of

the novel serine / threonine kinase Ndr2. J Biol Chem 2004; 279(44):45773-81


Tovote P, Meyer M, Beck-Sickinger AG, Von Horsten S, Ogren SO, Spiess J, Stiedl O. Central

NPY receptor-mediated alteration of heart rate dynamics in mice during expression of fear

conditioned to an auditory cue. Regul Peptides 2004; 120:205-14


Voikar V, Rossi J, Rauvala H, Airaksinen MS. Impaired behavioural flexibility and memory in

mice lacking GDNF family receptor alpha2. Eur J Neurosci 2004; 20(1):308-12


Voikar V, Vasar E, Rauvala H. Behavioral alterations induced by repeated testing in C57BL/6J

and 129S2/Sv mice: implications for phenotyping screens. Genes Brain Behav 2004; 3:27-38
















2003

Balschun D, Wolfer DP, Gass P, Mantamadiotis T, Welzl H, Schuetz G, Frey JU, Lipp HP. Does

cAMP response element-binding protein have a pivotal role in hippocampal synaptic

plasticity and hippocampus-dependent memory. J Neurosci 2003; 23(15):6304-14


Blank T, Nijholt I, Grammatopoulos DK, Randeva HS, Hillhouse EW, Spiess J. Corticotropin-

releasing factor receptors couple to multiple G-proteins to activate diverse intracellular

signaling pathways in mouse hippocampus: role in neuronal excitability and associative

learning. J Neurosci 2003; 23(2):700-7


Blank T, Nijholt I, Kye MJ, Radulovic J, Spiess J. Small-conductance, Ca2+-activated K+

channel SK3 generates age-related memory and LTP deficits. Nat Neurosci 2003; 6(9):911-2


Fischer A, Sananbenesi, Schrick C, Spiess J, Radulovic J. Regulation of contextual fear

conditioning by baseline and inducible septo-hippocampal cyclin-dependent kinase 5.

Neuropharmacology 2003; 44:1089-99


Fleischmann A, Hvalby O, Jensen V, Strekalova T, Zacher C, Layer LE, Kvello A, Reschke M,

Spanagel R, Sprengel R, Wagner EF, Gass P. Impaired long-term memory and NR2A-type

NMDA receptor-dependent synaptic plasticity in mice lacking c-FOS in the CNS. J Neurosci

2003; 23(27):9116-22


Laxmi TR, Stork O, Pape HC. Generalisation of conditioned fear and its behavioral expression

in mice. Behav Brain Res 2003; 145:89-98


Maciejak P, Taracha E, Lehner M, Szyndler J, Bidzinski A, Skorzewska A, Wislowska A,

Zienowicz M, Plaznik A. Hippocampal mGluR1 and consolidation of contextual fear

conditioning. Brain Res Bull 2003; 62:39-45


Sananbenesi F, Fischer A, Schrick C, Spiess J, Radulovic J. Mitogen-activated protein kinase

signaling in the hippocampus and its modulation by corticotropin-releasing factor receptor 2:

a possible link between stress and fear memory. J Neurosci 2003; 23(36):11436-43


Seidenbecher T, Laxmi TR, Stork O, Pape HC. Amygdalar and hippocampal theta rhythm

synchronization during fear memory retrieval. Science 2003; 301(5634):846-50


Stiedl O, Meyer M, Kishimoto T, Rosenfeld MG, Spiess J. Stress-mediated heart rate

dynamics after deletion of the gene encoding corticotropin-releasing factor receptor 2. Eur J

Neurosci 2003; 17:2231-5


Strekalova T, Zoerner B, Zacher C, Sadovska G, Herdegen T, Gass P. Memory retrieval after

contextual fear conditioning induces c-Fos and JunB expression in CA1 hippocampus. Genes

Brain Behav 2003; 2(1):3-10















2002

Blank T, Nijholt I, Eckart K, Spiess J. Priming of long-term potentiation in mouse

hippocampus by corticotropin-releasing factor and acute stress: implications for

hippocampus-dependent learning. J Neurosci 2002; 22(9):3788-94


Fischer A, Sananbenesi F, Schrick C, Spiess J, Radulovic J. Cyclin-dependent kinase 5 is

required for associative learning. J Neurosci 2002; 22(9):3700-07


Sananbenesi F, Fischer A, Schrick C, Spiess J, Radulovic J. Phosphorylation of hippocampal

Erk-1/2, Elk-1, and p90-Rsk-1 during contextual fear conditioning: interactions between Erk-

1/2 and Elk-1. Mol Cell Neurosci 2002; 21:463-76


2001

Lee HJ, Berger SY, Stiedl O, Spiess J, Kim JJ. Post-training injections of catecholaminergic

drugs do not modulate fear conditioning in rats and mice. Neurosci Lett 2001; 303:123-26


Otto C, Kovalchuk Y, Wolfer DP, Gass P, Martin M, Zuschratter W, Grone HJ, Kellendonk C,

Tronche F, Maldonado R, Lipp HP, Konnerth A, Schuetz G. Impairment of mossy fiber long-

term potentiation and associative learning in pituitary adenylate cyclase activating

polypeptide type I receptor-deficient mice. J Neurosci 2001; 21:5520-7


Stork O, Stork S, Pape HC, Obata K. Identification of genes expressed in the amygdala during

the formation of fear memory. Learn Mem 2001; 8:209-19


2000

Kishimoto T, Radulovic J, Radulovic M, Lin C, Schrick C, Hooshmand F, Hermanson O,

Rosenfeld M, Spiess J. Deletion of Crhr2 reveals an anxiolytic role for corticotropin-releasing

hormone receptor-2. Nat Genet 2000; 24:415-9


Stiedl O, Misane I, Spiess J, Ogren SO. Involvement of the 5-HT1A receptors in classical fear

conditioning in C57BL/6J mice. J Neurosci 2000; 20(22):8515-27


Stiedl O, Birkenfeld K, Palve M, Spiess J. Impairment of conditioned contextual fear of

C57BL/6J mice by intracerebral injections of the NMDA receptor antagonist APV. Behav Brain

Res 2000; 116:157-68


1999

Radulovic J, Ruhmann A, Liepold T, Spiess J. Modulation of learning and anxiety by

corticotropin-releasing factor (CRF) and stress: differential roles of CRF receptors 1 and 2. J

Neurosci 1999; 19(12):5016-25













Stiedl O, Radulovic J, Lohmann R, Birkenfeld K, Palve M , Sananbenesi F, Spiess J. Strain and

substrain differences in context-and tone-dependent fear conditioning of inbred mice. Behav

Brain Res 1999; 104:1-12


Stiedl O, Palve M, Radulovic J, Birkenfeld K, Spiess J. Differential impairment of auditory and

contextual fear conditioning by protein synthesis inhibition in C57BL/6N Mice. Behav

Neurosci 1999; 113(3):496-506


1998

Gass P, Wolfer DP, Balschun D, Rudolph D, Frey U, Lipp HP, Schuetz G. Deficits in memory

tasks of mice with CREB mutations depend on gene dosage. Learn Mem 1998; 5:274-88


Milanovic S, Radulovic J, Laban O, Stiedl O, Henn F, Spiess J. Production of the Fos protein

after contextual fear conditioning of C57BL/6N mice. Brain Res 1998; 784:37-47


Radulovic J, Kammermeier J, Spiess J. Relationship between Fos production and classical

fear conditioning: effects of novelty, latent inhibition, and unconditioned stimulus

preexposure. J Neurosci 1998; 18(18):7452-61


Radulovic J, Kammermeier J, Spiess J. Generalization of fear responses in C57BL/6N mice

subjected to one-trial foreground contextual fear conditioning. Behav Brain Res 1998;

95:179-89


1997

Stiedl O, Spiess J. Effect of tone-dependent fear conditioning on heart rate and behavior of

C57BL/6N mice. Behav Neurosci 1997; 111(4):703-11











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Fear Conditioning - TSE Systemsdownload.tse-systems.com/TSE_FCS_mouse_Publications.pdf · Last updated November 2014 [email protected] Publications for Fear Conditioning System