2

F e d e r a t i o n o f A m e r i c a n S o c i e t i e s f o r E x p e r i m e n t a l B i o l o g y Annual Report 2006[ ]

Q u a l i t y L i f e T h r o u g h R e s e a r c h

Ta b l e o f C o n t e n t s

FASEB Member Societies ......................................................2

FASEB Board ..........................................................................2

President’s Report ..................................................................3

Executive Director's Report ....................................................5

FASEB Public Affairs ..............................................................8

Collaborative Efforts ............................................................12

FASEB Committees ..............................................................14

The FASEB Journal ..............................................................24

FASEB Departments ............................................................26

FASEB Clients ......................................................................26

Financial Report ..................................................................27

Member Societies of the Federation ....................................32

[ ]

F e d e r a t i o n o f A m e r i c a n S o c i e t i e s f o r E x p e r i m e n t a l B i o l o g y

M i s s i o n S t a t e m e n t

The Federation of American Societies for Experimental

Biology (FASEB) advances biological science through

collaborative advocacy for research policies that promote

scientific progress and education and lead to improve-

ments in human health.

[ ]

Q u a l i t y L i f e T h r o u g h R e s e a r c h

F A S E B

FASEB MEMBER SOCIETIES

The American Physiological Society – APS

American Society for Biochemistry and Molecular

Biology – ASBMB

American Society for Pharmacology and

Experimental Therapeutics – ASPET

American Society for Investigative Pathology – ASIP

American Society for Nutrition – ASN

The American Association of Immunologists – AAI

American Association of Anatomists – AAA

The Protein Society

Society for Developmental Biology – SDB

American Peptide Society – APepS

Association of Biomolecular Resource

Facilities – ABRF

The American Society for Bone and Mineral

Research – ASBMR

American Society for Clinical Investigation – ASCI

Society for the Study of Reproduction – SSR

Teratology Society

The Endocrine Society – TES

The American Society of Human Genetics – ASHG

Society for Gynecologic Investigation – SGI

Environmental Mutagen Society – EMS

International Society for Computational

Biology – ISCB

American College of Sports Medicine – ACSM

FASEB BOARD

Officers

President – Leo T. Furcht

President-Elect – Robert E. Palazzo

Past President – Bruce R. Bistrian

Vice President for Science Policy – John A. Smith

Treasurer – Kenneth G. Mann

Secretary – Guy C. Fogleman

Directors

Richard B. Marchase (Past VP for Science Policy)

D. Neil Granger (APS)

Judith S. Bond (ASBMB)

David B. Bylund (ASPET)

Peter A.Ward (ASIP)

Dennis M. Bier (ASN)

Fred D. Finkelman (AAI)

Mark O. Lively (ABRF) (VP-Elect for Science Policy)

Kathryn J. Jones (AAA)

Gerald L. Hazelbauer (Protein)

Peter H. Mathers (SDB)

Fred R. Naider (APepS)

Paula H. Stern (ASBMR)

Gregory G. Germino (ASCI)

Virendra B. Mahesh (SSR)

John M. DeSesso (Teratology)

Henry M. Kronenberg (TES)

Loraine A. Oman-Ganes (ASHG)

James C. Rose (SGI)

Jeffrey L. Schwartz (EMS)

Barbara Bryant (ISCB)

Carl Foster (ACSM)

Advisors

Heidi E. Hamm (ASBMB)

James E. Barrett (ASPET)

David H. Baker (ASN)

Mark R. Boothby (AAI)

Joseph C. LaManna (AAA)

Richard A. Houghten (APepS)

Jay W. Fox (ABRF)

Asgerally T. Fazleabas (SSR)

Linda C. Giudice (SGI)

Michael Gribskov (ISCB)

[ ]

All information reported as of December 31,2006

2

“”

... we persevered, meetingwith congressional staffand continuing to pressour positions, and towardsthe end of the year—in an incredible flurry of activity—our persistencepaid off.

This year it has been my privilege to be a part of a very dynam-

ic organization that is making a major impact on policies

affecting biomedical science. FASEB plays a critical role in

advocacy for researchers, and I would like to highlight a few of

our major accomplishments of 2006.

When I took office in July, I was able to build upon the efforts

started by my predecessor, Bruce Bistrian. Under his steward-

ship, FASEB energetically supported the efforts of moderates in

Congress to raise the funding level for health and research spending in the FY 2007 budget.

FASEB also strongly supported competitiveness initiatives that proposed substantial funding

increases for NSF and DOE. While the struggle would be long and the outcome uncertain

for many months, this effort proved critical in the final stages of the appropriations process.

In May and June, scientists from our Member Societies contacted their Representatives and

successfully encouraged the House to pass the Stem Cell Research Enhancement Act. The

Senate passed the stem cell bill in July and the issue of stem cell research became an

important election issue propelling many new pro-science candidates into office.

Then, with lengthy recesses for holidays and elections, many observers felt major legislation

pertaining to research would never even come to a vote. But we persevered, meeting with

congressional staff and continuing to press our positions, and towards the end of the

year—in an incredible flurry of activity—our persistence paid off. Legislation to protect

researchers’ working with animals, the Animal Enterprise Terrorism Act (AETA), was passed

by the House and Senate and signed by the President in late November. FASEB worked

closely with the National Association for Biomedical Research, the driving force behind

AETA, and mobilized the scientific community in support of this important legislation. In

December, as the FASEB Board was holding its meeting, the NIH Reform Act was passed by

the House and Senate. To express his gratitude for our role in shaping the legislation to

meet the concerns of scientists, Joe Barton, Chair of the House Energy and Commerce

Committee, traveled to Rockville, Maryland, to thank the Board personally for FASEB’s sup-

port on this measure. The ultimate impact of our advocacy on the FY 2007 funding bills

did not completely play out until the first few weeks of 2007, when Congress passed the FY

2007 Joint Funding Resolution that contained a $619 million increase for the NIH plus

major increases in funding for NSF and DOE. The additional funds for research were the

3

P r e s i d e n t ’ s R e p o r t[ ]

Leo Furcht, M.D.

4

result of strong actions by our chief supporters in Congress, but FASEB’s work mobilizing scien-

tists did not go unnoticed; a Nature editorial cited FASEB’s advocacy efforts as a major factor

contributing to this outcome.

Much of our success is attributable to the outstanding work of the FASEB staff. Jon Retzlaff

worked tirelessly to convey the views of the research scientists to the House Energy and

Commerce staff working on NIH reauthorization, and as a result, they ultimately came to appre-

ciate and adopt our positions. Carrie Wolinetz has earned the respect of the entire research

community with her finely crafted position statements and widely praised slide presentations

on the benefits of NIH-supported research. A grant from the Office of Research Integrity to

Laura Brockway is enabling us to build a coalition of organizations committed to ensuring that

the views of individual investigators are heard in the policy debate over financial conflict of

interest in academic-industry relations, and resources developed by Jennifer Hobin, Marnie

Halpern, and their colleagues on the Educating About Evolution Subcommittee, which pro-

motes evolution education in the schools, were featured in Science and praised by the National

Center for Science Education.

Certainly one of the highlights of the year was our recruitment of Guy Fogleman, to become

executive director of FASEB. His leadership skills and management expertise were apparent to

all of us who met with him during the interviewing process, and we were very pleased when he

decided to join us in July. In the short time that Guy has been at FASEB he has more than justi-

fied the confidence that we placed in him, and his personal style and attention to the needs of

the organization have dramatically improved the relations between FASEB and the Member

Societies. As we face new and mounting challenges in the future, one thing is certain: with its

new management, FASEB will be in a stronger position to address them.

As a result of our efforts on behalf of the individual investigator in the biomedical and related

life sciences, FASEB’s influence among policymakers has never been greater. Our views on leg-

islation and major research issues are directly solicited by members of Congress and the heads

of major federal agencies. Senior staff are in regular contact with us, seeking our views and

expressing their gratitude for our advice and support.

I am very proud of what we have accomplished and am confident that we face a bright future.

With the active support of the FASEB Member Societies, we will continue to advance research

and education in the biomedical and related life science. n

P r e s i d e n t ’ s R e p o r t

“”

FASEB is a great organization with a distinguished historyand an important mission.

FASEB is a great organization with a distinguished history and

an important mission. I am delighted to have the privilege of

serving as its Executive Director and working with its very tal-

ented and impressive staff. I am mindful of the fact that FASEB

exists because our Member Societies want us to exist and find

value in belonging to this Federation. During my tenure so far, I

have greatly benefited from the counsel of the Society

Executive Officers, both individually and through the Executive

Officers Advisory Committee, and am looking forward to contin-

ued productive and collegial interactions in the future.

FASEB’s volunteer leadership is an essential and integral component of the Federation.

2006 was a year of significant change in FASEB’s governance structure: we successfully

made the transition from two to one Board member from each Member Society. Amid con-

cerns about a smaller pool of potential officers, five people ran for the office of President,

showing that interest in participating in FASEB’s governance continues to be high. Our offi-

cers, Board members, and committee members lead our advocacy and other activities.

They are actively engaged in the oversight and the setting of strategic direction for FASEB

through regular teleconferences and face-to-face meetings.

The many successes of our public affairs activities are enumerated in other sections of this

report, so I will not dwell on them here. But I will say that, under the leadership of our

Deputy Executive Director for Policy, Howard Garrison, 2006 was a year in which FASEB

came into its own as a major player on the national policy scene. One of many measures

of our success in this area is that products of the Office of Public Affairs, such as our state-

specific NIH Advocacy presentations and our Breakthroughs in Bioscience articles, are

increasingly requested and used by the Research Education and Advocacy community.

The FASEB Journal Editorial Board has been very active, holding its first-ever meeting in

New York in May 2006. FJ’s new Editor-in-Chief, Gerald Weissmann, completed his first full

year in that role. The results of their efforts in the style and relevance of the FJ have been

remarkable and were noticed by many; I recently heard FJ referred to as avant-garde.

Financially, 2006 was a good year for FASEB. Scientific meetings (including Summer

Research Conferences) and The FASEB Journal continue to be significant sources of

E x e c u t i v e D i r e c t o r ’ s R e p o r t[ ]

Guy Fogleman, Ph.D.

5

6

revenue for the organization. Based on projections from the FASEB financial model developed

by our Deputy Executive Director and Chief Financial Officer, Anthony Fragnito, we determined

that it would be beneficial to pre-fund our 2007 debt service requirement (associated with the

new office building and parking structure on the Beaumont campus) during 2006. The strength

of our investment portfolio also served FASEB well in 2006. We took advantage of favorable

conditions in the bond markets to execute an interest rate swap contract tied to the tax-exempt

bond used to finance our campus construction activities. This “swap”had the same effect as

converting from a floating rate mortgage to a fixed rate mortgage, locking in a very good inter-

est rate. We are also pleased that the Association for the Accreditation of Human Research

Protection Programs, an organization for which FASEB is a founding partner as well as a finan-

cial guarantor, is becoming stable financially.

Our beautiful campus in Bethesda underwent several upgrades in 2006. We retrofitted the old-

est (circa 1960s) sections of the Lee Building with a new sprinkler system for fire suppression.

We also completed a pass-through at the back of the FASEB campus that allows those who

work on campus to exit by automobile in a considerably safer and more convenient manner.

Our Managed Society Services Department completed its first full year of operation, successful-

ly bringing six new clients (all biology-or biomedical-oriented associations) under contracts for

management services. This increased activity also created additional business for other FASEB

departments. FASEB departments continue to provide financial, information technology, pro-

duction and postal, meetings management, human resources, dues and subscriptions, and pub-

lishing services to our Member Societies as well as to other biology-oriented associations.

One significant value that FASEB provides for our Member Societies is through the Minority

Access to Research Careers (MARC) program, which is funded by grants from the National

Institute of General Medical Sciences’ Division of Minority Opportunities in Research. The

MARC program sponsored 382 travel awards to Member Society scientific meetings, Summer

Courses, and Summer Research Conferences. In addition, 79 awards to participate in FASEB

Summer Research Opportunity Programs were sponsored through the MARC program. FASEB

also received several grants from the Burroughs Wellcome Fund in 2006, including a $15,000

grant to support a new FASEB Diversity Award, with a commitment to continue funding this

award for five years.

While we have had significant successes, we know that FASEB has a number of challenges

going forward: How do we best set priorities for advocacy in the era post the doubling of the

NIH budget? How will FASEB be affected by the trend that a growing proportion of many of

our Societies’ members are from outside the US? What are the options for the long-term

E x e c u t i v e D i r e c t o r ’ s R e p o r t

evolution of the FASEB campus? What strategies and goals should FASEB set as the Federation

approaches its centennial in 2012? I am confident that FASEB’s staff, together with our

volunteer leadership and our partners in the Member Societies, will be able to rise to these

challenges.

My vision for the future of FASEB revolves around three key themes: Leadership, Financial

Stability, and Workforce Development. With respect to leadership, FASEB must continue to be a

major force in national biomedical research policy, and must be proactive in providing state of

the art and cost effective services to our Member Societies. Our finances need to be such that

our revenue covers operations plus routine deposits to our reserve fund, enabling our reserve

fund to grow even with occasional withdrawals for Board-approved special projects. I would

like FASEB to be a great place to work for our employees and for all the organizations that call

our campus home. Initial steps were taken in these directions in 2006. After carefully studying

the FASEB organization, I restructured the reporting relationships for FASEB departments so

that they are grouped according to their major functions, and restructured the FASEB

Executive Office so that we can be increasingly open and responsive to the needs of the

organization. We have also initiated a working group of FASEB employees to review and make

recommendations on workforce development issues.

I believe that FASEB’s role in the future, as a primary advocate for research and as a provider

of critical services to our Member Societies, will only increase in importance. I am very much

looking forward to working with all of our stakeholders to ensure FASEB’s success in these

areas. n

“”

My vision for the futureof FASEB revolvesaround three keythemes: Leadership,Financial Stability, andWorkforce Development.

7

E x e c u t i v e D i r e c t o r ’ s R e p o r t

F A S E B O f f i c e o f P u b l i c A f f a i r s[ ]

8

Advocacy for biomedical research and shaping of

related policies on behalf of working scientists are

the chief missions of the FASEB Office of Public

Affairs (OPA).Working with FASEB leadership,

Member Society staff, government officials, and advo-

cacy partners, the OPA staff helps to facilitate a pro-

ductive exchange among the scientific community,

the Federal government, and the public. FASEB’s rep-

utation as the voice of the biomedical research com-

munity is such that when issues related to science

arise, legislators, federal agencies, and other organiza-

tions come seeking FASEB’s views.

FASEB: A Strong Voice for Biomedical

Research: 2006, Year in Review

While the announcement of the President’s American

Competitiveness Initiative (ACI), which proposed to

double the funding for science at the National

Science Foundation and Department of Energy’s

Office of Science, was welcomed news to the scientif-

ic community, the funding prospect for the National

Institutes of Health (NIH) appeared grim. The

President’s budget called for flat-funding of NIH and

Congress seemed determined to maintain a fiscal

standard that would not have allowed additional dol-

lars for medical research. FASEB began the year with

an aggressive advocacy strategy, taking aim at the

congressional budget resolution, and in response to

FASEB’s call to action, nearly 9,000 letters were gener-

ated by scientists, resulting in passage of an amend-

ment to allow greater funding for health and educa-

tion programs, including NIH. This was merely the

first volley in a year-long effort to generate grassroots

activity and maintain FASEB’s high-profile on Capitol

Hill, ultimately culminating in a significant increase

for NIH in FY 2007.

Funding for biomedical research was only one of

many issues addressed by FASEB in 2006. It was a

year marked by the first presidential veto on embry-

onic stem cell legislation, successes in defeating pro-

posed export regulations that could have dramatical-

ly affected academic researchers, and FASEB’s efforts

on behalf of young scientists. On July 1st, FASEB

President Leo T. Furcht, succeeded Bruce R. Bistrian,

in leading the Federation on issues related to NIH

reauthorization, conflict-of-interest, embryonic stem

cells, the use of animals in research, and other policy

issues of crucial importance to the scientific

community.

FASEB Plays Pivotal Role in

Shaping the Future of NIH

One of the final actions of the 109th United States

Congress was to pass the National Institutes of Health

Reform Act, a landmark piece of legislation that reau-

thorized the NIH for the first time in more than 13

years. In cooperation with Chairman Joe Barton (R-

TX) of the House Energy and Commerce Committee,

FASEB played a major role in shaping, improving, and

ultimately passing the NIH reauthorization bill.

Through the tireless efforts of FASEB Legislative

Government& Legislative

Liaison

FASEBOffice of

Public Affairs

PublicOutreach

PolicyDevelopment

CoalitionBuilding

Communication

Research& Analysis

F A S E B O f f i c e o f P u b l i c A f f a i r s

Director Jon Retzlaff and President Leo Furcht, FASEB

had exclusive input into the developing legislation,

resulting in a vision for NIH that emphasized investi-

gator-initiated research, improved transparency, and

sustainable funding levels. President Furcht testified

before the House Energy and Commerce Committee

in September in support of the NIH Reform Act, and

Chairman Barton credited FASEB’s efforts during an

appearance at the December meeting of the FASEB

Board of Directors. During a successful attempt to

defeat amendments to the bill that would have ear-

marked programmatic funds for NIH, a FASEB letter

in opposition to targeted research funding was read

on the House floor. Following nearly unanimous pas-

sage by both houses of Congress, the bill was signed

into law by President Bush.

Advocacy Triumph Results

in Significant Boosts to

Research Funding

FASEB’s efforts to influence the Senate and House

Budget Resolutions resulted in passage of amend-

ments to significantly increase the discretionary pool

available for medical research and other health pro-

grams. FASEB continued its campaign during the

second annual FASEB Capitol Hill Day in which more

than two dozen scientists from the Board of Directors

and Science Policy Committee met with their legisla-

tors and key members of congressional leadership.

The Federation’s efforts drew widespread national

attention in articles published in the Wall Street

Journal, USA Today, and with interviews with the

FASEB President on National Public Radio and

CNBC. Record numbers of scientists contacted mem-

bers of Congress, answering FASEB’s call to action to

increase funding for NIH. Victory was accomplished

upon completion of the FY 2007 funding process,

which contained a $620 million increase for NIH, a

remarkable achievement at a time when most federal

programs received no increase at all.

In addition to the substantial increase for NIH, the

National Science Foundation (NSF) and Department

of Energy also fared well in FY 2007, each receiving a

significant increase over the previous fiscal year.

FASEB strongly supported the President’s proposal

and subsequent congressional legislation to double

the budgets of these two critical agencies. When the

competitiveness legislation and NSF’s proposed strate-

gic plan excluded the biological sciences, FASEB suc-

cessfully campaigned for correction of these over-

sights. As a cosponsor of the National Academies

convocation on its influential report Rising Above the

Gathering Storm, FASEB expressed its support for an

increased investment in all sciences, as well as

science education. In addition to NIH, NSF, and DOE,

the competitive research portfolio of the United

States Department of Agriculture, another program for

which FASEB advocates, received an increased

funding level of $190 million.

Continued Leadership on Conflict of

Interest Gains National Attention

FASEB’s activities regarding conflict of interest issues

were recognized in July when Laura Brockway of

OPA received a grant of $112,000 from the NIH Office

of Research Integrity (ORI) to address conflict of

9

FASEB Board Members present the 2006 FASEB Public Service Award toRepresentative Mike Castle (R-DE) for his tremendous leadership and outstandingcommitment to health programs, including NIH.

interest management in biomedical research. The

grant, funded through a collaborative program

between ORI and the Association of American

Medical Colleges, supports an extension of the work

described in the FASEB report, Shared Responsibility,

Individual Integrity: Scientists Addressing Conflicts of

Interest in Biomedical Research, which detailed the

results of a consensus conference organized by

FASEB to provide guidelines for scientists engaged in

academic-industrial partnerships. The ORI-funded

project is focusing on forming a coalition of scientific

societies, establishing a new consensus on standards

of conduct, and developing educational materials for

use by scientists. FASEB’s project received national

press coverage and articles on FASEB’s endeavors

were accepted for publication in The FASEB Journal

and Journal of the American Medical Association.

FASEB Helps Pass Historic Animal

Rights Terrorism Legislation

On November 27, 2006, President Bush signed S. 3880,

the Animal Enterprise Terrorism Act (AETA), into law.

FASEB worked actively to pass this legislation, which

increases protections for researchers targeted by ani-

mal rights extremists, who advocate arson, personal

violence, and vandalism as appropriate means to end

the use of animals in research. In support of the bill,

FASEB submitted testimony and letters to the House

and Senate Judiciary committees, as well as meeting

with congressional staff to convey the importance of

ensuring the security of biomedical researchers.

Scientists throughout the country took action in

response to FASEB alerts, urging Congress to pass the

AETA, an effort that proved victorious.

Unfortunately, activities to hinder animal research con-

tinued on multiple fronts. In May, FASEB took swift

action to defeat animal rights supporters who were

seeking to have language harmful to research added

to the FY 2007 Agriculture Appropriations Bill. The

Federation contacted the chair of the House

Agriculture Appropriations Subcommittee urging that

they reject efforts to deny funding to institutions pur-

chasing animals from Class B Dealers. As a result of

FASEB and the biomedical research community’s vigi-

lance and advocacy, no such limitations were added

in the bill. In addition to a FASEB letter published in

the Baltimore Sun, decrying an opinion piece filled

with misinformation about the use of animal

research, FASEB is continuing to monitor and com-

ment on the Institute of Laboratory Animal Research’s

project to update their report on laboratory animal

pain and distress.

Communicating the Message:

Scientists, Congress and the Public

Now more than ever, biomedical researchers are in

need of a voice to represent their interests to policy-

makers and the public. FASEB’s communication activ-

ities are threefold: bringing the perspective of science

to lawmakers; keeping the research community

informed on science policy issues; and conveying to

the general public the importance of biomedical

research. FASEB has achieved major success in

recruiting scientists to take action in support of bio-

medical research, as shown by the membership of our

e-Action list, which has grown rapidly to include near-

ly 13,000 self-identified science advocates. In an

ongoing effort to develop advocacy tools for use by

scientists, OPA launched two major products in 2006:

a slide presentation for local NIH advocacy and an

evolution advocacy toolkit.As part of its renewed

focus on grassroots activities by member society sci-

entists, FASEB unveiled a customizable slide presenta-

10

F A S E B O f f i c e o f P u b l i c A f f a i r s

tion that scientists, department heads, and deans can

use locally to demonstrate NIH’s impact on human

health. The slide presentation has been praised by

NIH Director Elias Zerhouni and cited in a

Congressional Research Service report as an example

of outreach activities by scientists. OPA is creating

slide presentations relevant to each state, which are

freely available on our website (http://opa.faseb.org)

and is collecting feedback from FASEB member soci-

eties on their usage.

Arming scientists with the tools they need to advo-

cate on behalf of critical issues is also the driving

force of FASEB’s new evolution advocacy toolkit

(www.evolution.faseb.org). This web-based resource

provides a variety of advocacy materials, including

sample letters-to-the-editor and op-ed pieces, modifi-

able PowerPoint presentations, and tips for working

with teachers, testifying at school board meetings,

and contacting public officials. The site, which was

recently highlighted in the journal Science, also pro-

vides background materials and talking points on the

science of evolution, the importance of evolution

education, and the problems with teaching “alterna-

tives.” To market the evolution advocacy toolkit,

FASEB created wearable buttons bearing the slogan

“Teach Evolution, Learn Science”and colorful palm-

cards. These materials have achieved their own pop-

ularity and have been distributed through a wealth of

venues, including the National Academies Koshland

Science Museum and the Marine Biological

Laboratories in Woods Hole, Massachusetts.

FASEB continues to expand its reach through

increased distribution of its Breakthroughs in

Bioscience series, illustrated articles explaining how

basic research results in medical advancement and

which are written for the non-scientist. An article on

11

breast cancer treatment, produced in partnership with

the Endocrine Society, is being distributed to all staff

members of the Susan G.

Komen Foundation and

given to patients through the

University of Miami’s Braman

Family Breast Cancer

Institute. In response to a

request from the patient

advocates at the National

Health Council, FASEB also

produced a brochure based

on the Breakthroughs series

titled “Science Fortune,”

which explains the role serendipity plays in biomedical

research discoveries.

Office of Public Affairs

Publications in 2006:

• Recommendations for Federal Funding for Biomedical

Research and Related Life Science Research – FY2008

(http://opa.faseb.org/ pdf/final_funding_ fy2008.pdf)

• Garrison, H. H., and Palazzo, R. E. (2006) What’s happen-

ing to the young investigator? The FASEB Journal.

20:1288–1289.

(http://www.fasebj.org/cgi/content/full/20/9/1288)

• Breast Cancer,Tamoxifen,and Beyond: Estrogen and

Estrogen Receptors,Breakthroughs in Bioscience

#21[in partnership with The Endocrine Society]

(http://opa.faseb.org/pdf/Breast_Cancer_Breakthru.pdf)

• Shared Responsibility, Individual Integrity: Scientists

Addressing Conflicts of Interest in Biomedical Research

(http://opa.faseb.org/pdf/FASEB_COI_paper.pdf)

• Science Fortune: How Unpredictable Research

Advances Have Saved Millions of Lives

(http://opa.faseb.org/pdf/ScienceFortuneBrochure.pdf)

F A S E B O f f i c e o f P u b l i c A f f a i r s

C o l l a b o r a t i v e E f f o r t s

Collaboration is inherent in FASEB’s coalition struc-

ture. The strength of the Federation lies in its com-

bined representation of its societies and their mem-

berships. FASEB also serves as a partner in coopera-

tive efforts, not only with external organizations, but

with its own members societies, working together to

achieve common goals.

Working Together in

Public Affairs

FASEB’s unique relationship with its Member

Societies allows collaborative activities that serve the

interests of both the coalition and individual society

members. Nowhere is this more evident that in

FASEB’s public affairs program. A few examples of

FASEB and its Member Societies taking advantage of

the opportunity to fulfill their missions together are

listed below.

• The Endocrine Society sponsored the FASEB

Breakthroughs in Bioscience article titled “Breast

Cancer,Tamoxifen, & Beyond: Estrogen and

Estrogen Receptors.” This joint effort has been a

great success, with nearly 5,000 copies of the article

having been distributed in partnership with

Endocrine Society members, the Susan G. Komen

Breast Cancer Foundation, and the Braman Family

Breast Cancer Institute.

• The American Society for Biochemistry and

Molecular Biology and FASEB united in an effort

to provide evolution advocacy tools to scientists

interested in preserving the integrity of science edu-

cation. All ASBMB members received palm cards

advertising the resources available in the toolkit in

the regular membership mailing. The palm cards

and matching evolution advocacy buttons were

12

Behind the Scenes – Public affairs Staff

LAURA BROCKWAY (Senior Science Policy Analyst) coordi-

nates the activities of the Science Policy Committee, and

is responsible for issues related to public access to sci-

entific literature, academic-industry relations, and tech-

nology transfer. She is the key staff member on FASEB’s

ongoing project related to conflicts of interest in bio-

medical research.

HOWARD H. GARRISON (Deputy Executive Director for

Public Affairs; Director,Office of Public Affairs) directs the

office and coordinates OPA activities with FASEB lead-

ership and society staff. In addition, He prepares

detailed analyses of trends in NIH funding and training

opportunities for scientists, which are used to bolster

OPA’s advocacy activities.

JENNIFER HOBIN (Science Policy Analyst) is responsible

for training and career development issues, including

those related to clinical research. She also directs

FASEB’s efforts related to the teaching of evolution.

SUZANNE PRICE (Communications Assistant) is responsi-

ble for the redesign and maintenance of the OPA web-

site, as well as editing and distributing press releases,

communication products, and reports. In addition, she

is tasked with customizing and updating FASEB’s state-

by-state NIH advocacy presentations.

JON RETZLAFF (Director, Legislative Relations) is FASEB’s

full-time presence on Capitol Hill, where he is able to

gather the most recent and relevant information, and to

assure congressional access for FASEB’s elected leader-

ship. His responsibilities include monitoring relevant

legislative developments, coordinating legislative strate-

gy with FASEB leadership, and directing FASEB’s com-

munications with members of Congress and their staffs.

CARRIE D. WOLINETZ (Director,Communications) directs

OPA communications with Member Societies, the

media and the general public. She is also responsible

for issues related to animal research, SCNT/stem cells,

and homeland security.

C o l l a b o r a t i v e E f f o r t s[ ]

13

also distributed at the annual meetings of The

American Society of Human Genetics, Society

for Developmental Biology, The American

Physiological Society, and The American

Society for Bone and Mineral Research.

• FASEB generates a monthly Washington Update

column for the American Society for

Biochemistry and Molecular Biology’s monthly

magazine, ASBMB Today, which informs ASBMB

members of FASEB’s government affairs activities.

The Office of Public Affairs has also contributed

periodic articles to the newsletters of The Protein

Society, American Association of Anatomists,

and American Society for Investigative

Pathology.

• FASEB provided its legislative alert system to The

American Physiological Society to enhance joint

efforts to halt legislation that would have would

have restricted biomedical research funding for

studies using animals purchased from Class B dealers.

Serving Scientists through

Cooperative Efforts

The service departments at FASEB work both for and

with the FASEB Member Societies. From Career

Resources to the Office of Scientific Meetings, the

pooled resources and combined efforts of FASEB and

its societies unite to serve the biomedical research

community.

• The FASEB Minority Access to Research Careers

(MARC) Program provides funding for travel awards

to support the participation of faculty/ mentors and

students, and poster/platform (oral) presenters at

Member Society meetings and conferences, as well

as FASEB Summer Research Conferences. This has

included awards to attend meetings of nearly every

FASEB Member Society, as well as sponsorship of

workshops or speakers at the meetings of the

American Society for Pharmacology and

Experimental Therapeutics, American Society

for Investigative Pathology, American

Association of Anatomists, and Society for

Developmental Biology.

• FASEB Member Societies, including the American

Society for Clinical Investigation, The

American Society for Bone and Mineral

Research, The American Society for Human

Genetics, The American Association of

Immunologists, and the societies participating in

the Experimental Biology Meeting, have part-

nered with FASEB’s Office of Scientific Meetings for

educational activities associated with continuing

medical education.

• In 2006,The Endocrine Society joined FASEB to

cosponsor part of FASEB’s highly successful Summer

Research Conference (SRC) series. The SRC pro-

gram is itself a collaborative effort, with members of

the FASEB societies serving on the SRC Advisory

Committee and selecting conferences from propos-

als submitted by FASEB Member Societies.

• The FASEB Career Resources program was involved

in numerous cooperative efforts with FASEB soci-

eties throughout the year, including providing virtual

career fair services at the meetings on The

American Association for Immunologists and

The American Society for Human Genetics. n

C o l l a b o r a t i v e E f f o r t s

EXECUTIVE OFFICERS ADVISORY COMMITTEE,

Guy Fogleman, Chair

The Executive Officers Advisory Committee (EOAC)

is a standing committee of the Board, that “shall

address itself to items of mutual interest to the

Federation and the Member Societies”(FASEB

Bylaws,Article VII, Section 3). The EOAC met

approximately twice a month in 2006 and consid-

ered a wide range of issues. Each meeting was

divided into two sections, one dealing with cross-

cutting issues of interest to all of the societies (e.g.,

the advocacy agenda, Continuing Medical

Education applications, FASEB finances, meeting

planning, publications,Association Management

System software packages, etc.) and one limited to

issues of primary concern to those societies resid-

ing on campus (e.g., FASEB services, building and

grounds, conference center usage, etc.). Reports of

activities of each FASEB Member Society are pre-

sented to the EOAC for the joint purposes of infor-

mation sharing and soliciting advice. The EOAC

continues to review and develop positions on all of

the major issues brought to the FASEB Board.

EOAC Members

Guy C. Fogleman (FASEB)

Martin Frank (APS)

Barbara Gordon (ASBMB)

Christine K. Carrico (ASPET)

Mark E. Sobel (ASIP)

John Courtney (ASN)

M. Michele Hogan (AAI)

Andrea Pendleton (AAA)

Cindy A.Yablonski (Protein)

Ida Chow (SDB)

Jane V.Aldrich (APepS)

Jay W. Fox (ABRF)

Ann Elderkin (ASBMR)

John Hawley (ASCI)

Judith Jansen (SSR)

Tonia Masson (Teratology)

Scott B. Hunt (TES)

Elaine Strass (ASHG)

Ava Tayman (SGI)

Tonia Masson (EMS)

B. J. Morrison McKay (ISCB)

Jim Whitehead (ACSM)

F A S E B C o m m i t t e e s[ ]

FASEB’s strength in advocating for biomedical research is its diversity of disciplines and the large number of sci-

entists it represents. In order to ensure that the views of all Member Societies and the researchers they represent

are heard, FASEB is guided by its Board of Directors as well as committees focused on areas such as public

affairs, research conferences, and publications.

14

15

EXECUTIVE COMMITTEE, Leo T. Furcht, Chair

As directed by the FASEB Bylaws (Article VII, Section

2, available on the FASEB web site), the Executive

Committee is a standing committee of the Board that

consists of the officers of the Board. The Committee

meets weekly to “exercise the management authority

of the Board of Directors in between meetings of the

Board of Directors.”

In 2006, with rare exceptions, the Committee met

weekly with the Director of the Office of Public

Affairs and the Chief Financial Officer to review the

events of the week. The agenda is usually divided

equally between issues related to advocacy by the

organization and issues related to the business func-

tions of the FASEB campus.

The business of running FASEB is reviewed with spe-

cial attention to fiscal matters for review and

approval by the Finance Committee, campus issues,

and relationships with FASEB Member Societies,

managed societies, and nonmember societies. The

activities of other committees of FASEB are reviewed

weekly, as needed, including the agendas of the

Executive Officers Advisory Committee, the

Department Heads Meetings, etc. Planning of FASEB

Board Meetings is also a function of this committee,

as is the general oversight of FASEB staff. The voting

officer members of the Executive Committee make

up the Nominating Committee and recommend a

slate of candidates for election as officers of the

organization.

Executive Committee Members

Leo T. Furcht

Robert E. Palazzo

Bruce R. Bistrian

Kenneth G. Mann

John A. Smith

Guy C. Fogleman

PUBLIC AFFAIRS COMMITTEE, Robert E. Palazzo, Chair

The Public Affairs Committee (which is made up of

the members of the Executive Committee together

with two Board Members elected annually) meets

monthly to respond to issues generated by the

Executive Committee and assist in prioritization for

the SPC and the Board. In 2006, the PAC began to

hold semiannual face-to-face meetings to set long-

term pubic affairs priorities for the Federation.

Public Affairs Committee Members

Robert E. Palazzo

Richard B. Marchase

Leo T. Furcht

Bruce R. Bistrian

Mark Lively

Kenneth G. Mann

David B. Bylund

John A. Smith

Paula H. Stern

Howard H. Garrison*

Guy C. Fogleman*

*Ex officio, non-voting

THE SCIENCE POLICY COMMITTEE,

John Smith, Chair

The Science Policy Committee (SPC) is FASEB’s

“think-tank”and is charged with developing long-term

policies and consensus positions on issues of con-

cern to biomedical researchers. Previous chair of the

SPC,Vice-President for Science Policy Richard

Marchase, completed his term of office on June 30

and was succeeded by John Smith. Primarily working

through standing or ad hoc subcommittees, the SPC

became actively engaged in 2006 in several issues of

critical importance to the biomedical research com-

mittee, the highlights of which are detailed below.

F A S E B C o m m i t t e e s

Responding to Emerging Issues:

Peer Review Subcommittee

In June, the SPC held a joint symposium with the

FASEB Board of Directors entitled,“Peer Review:

Issues, Mechanisms, and Models.” The purpose of the

symposium was to initiate a discussion of the current

challenges faced by the NIH Center for Scientific

Review (CSR) and proposed solutions. Speakers

included: Elias Zerhouni, NIH Director; Antonio

Scarpa, CSR Director; Gerald M. Rubin,Vice-President

and Director, Janelia Farm Research Campus, Howard

Hughes Medical Institute; and Keith R.Yamamoto,

Professor and Executive Vice Dean, School of

Medicine, University of California San Francisco. As a

result of the symposium, FASEB formed a new sub-

committee on peer review, which has been actively

engaged in dialogue with Antonio Scarpa in making

recommendations for meeting the needs of the scien-

tific community in regard to peer review. Given the

crucial importance of this issue for biomedical

researchers, and its complexity, it is likely this new

subcommittee will play a significant role in future

FASEB policy development.

Serving the Next Generation:

Training and Career Opportunities

for Scientists

The Training and Career Opportunities subcommittee

of the SPC engaged in a number of activities through-

out 2006 that were related to serving the next genera-

tion of biomedical researchers. The subcommittee

has been especially concerned with meeting the

needs of postdoctoral fellows and initiated a joint

statement with the Association of American Medical

Colleges (AAMC) on uniform health benefits for post-

doctoral scientists. FASEB also joined with AAMC in

commenting on proposed changes to the Ruth L.

Kirschstein National Research Service Awards tuition

funding policy, and our suggestion that health bene-

fits be separated from calculation of tuition was ulti-

mately adopted by NIH. In addition, the subcommit-

tee has been working on a number of projects related

to career development issues of scientists, including a

proposal funded by the National Science Foundation

to use the SESTAT data base to examine scientific

career outcomes and continued efforts to facilitate

the use of FASEB’s Individual Development Plan for

postdoctoral scientists. The Training and Career

Opportunities subcommittee serves as a liaison

between the policy development functions of the SPC

and services provided by the Career Resources and

MARC programs.

Serving Science and Society: Enhanced

Access to Scientific Publications

Through the SPC’s Enhanced Public Access

Subcommittee, FASEB continues to support efforts to

increase access to scientific publications without dis-

rupting the successful model of scientific publication

established by not-for-profit scientific societies. The

subcommittee facilitated FASEB’s participation in a

proposal, together with nearly five dozen other organi-

zations, to establish a public-private partnership with

NIH that would meet the needs of both the federal

agency and the scientific society publishers. The

group monitors and reports on the activities of the

National Library of Medicine’s PubMed Central

Advisory Committee and Public Access Working

Group, which are spearheading NIH’s efforts to man-

date access to published information. On the legisla-

tive front, the Enhanced Public Access Subcommittee

worked to defeat efforts to add deleterious language

regarding “open access”publication to the appropria-

tions bill that funds NIH, as well as strongly opposing

the Federal Research Public Access Act of 2006.

This bill, sponsored by Senators John Cornyn (R-TX)

and Joseph Lieberman (D-CT), would have mandated

that all federally funded research results be made

available online within six months of publication. Via

the SPC committee, FASEB expressed concern that the

legislation jeopardizes crucial processes, such as peer

review, and hinders scientific societies’ ability to pro-

vide services to the scientific community and the

16

F A S E B C o m m i t t e e s

17

public. Although the advocacy efforts of FASEB

proved successful in preventing the bill from passing

the Senate committee to which it had been referred,

the subcommittee continues to monitor and address

similar legislation.

Subcommittees and Chairs of the

Science Policy Committee, 2006

• Animals in Research and Education Issues,

William Talman (APS)

• Breakthroughs in Bioscience, Fred Naider (ApepS)

• Clinical Research, Janet Hall (Jan.-Aug.) and Jane

Reusch (Sept.-Dec.) (Endocrine)

• Educating About Evolution, Marnie Halpern (SDB)

• Enhanced Public Access Committee,

Patsy Brannon (ASN)

• NIH Issues, Robert Palazzo (ASBMB)

• Peer Review, Gail Bishop (AAI)

• Stem Cells & SCNT Subcommittee,

Peter Mathers (SDB)

• Training and Careers Subcommittee,

Joseph LaManna (AAA)

SPC Members

John A. Smith (APepS),

Vice President for Science Policy**

William T.Talman (APS)

Peter A. Rubenstein (ASBMB)

Henry R. Besch, Jr. (ASPET)1

James E. Barrett (ASPET)

Avrum I. Gotlieb (ASIP)

Patsy M. Brannon (ASN)

Gail A. Bishop (AAI)

Joseph C. LaManna (AAA)

A. Joshua Wand (Protein)

Marnie E. Halpern (SDB)

Peter H. Mathers (SDB)

Ted Thannhauser (ABRF)

Larry Suva (ASBMR)

David H. Gutmann (ASCI)

Joanne Fortune (SSR)

Thomas B. Knudsen (Teratology)

Jane E. Reusch (TES)

Nanette Santoro (SGI)

Jeffrey L. Schwartz (EMS)

Greg Tucker-Kellogg (ISCB)

Charlotte (Toby) A.Tate (ACSM)

Mark O. Lively (ABRF),

Vice President-Elect for Science Policy

Richard B. Marchase,

Past Vice President for Science Policy

Howard H. Garrison - Deputy Executive Director for

Policy; Director, Office of Public Affairs (FASEB)*

Guy C. Fogleman - Executive Director (FASEB)*

1Deceased March 17, 2007

**Non-voting; *Ex-officio, non-voting

EXCELLENCE IN SCIENCE AWARD COMMITTEE,

Marianne Wessling-Resnick,Chair

The Excellence in Science Award is sponsored by Eli

Lilly and Company to recognize outstanding achieve-

ment by women in biological science. All women

who are members of one or more of the societies of

FASEB are eligible for nomination. Nominations rec-

ognize a woman whose career achievements have

contributed significantly to further our understanding

of a particular discipline by excellence in research

and who is an outstanding mentor for young scien-

tists at all levels of development.

An extraordinarily large and strong pool of women

scientists nominated for the Excellence in Science

Award has made the selection of winners difficult for

the past several years. In 2006, 82 nomination pack-

ages meeting award criteria were received and the

committee ultimately selected two recipients—Dr.

Marilyn Farquahr and Dr. Elaine Fuchs. The

Excellence in Science Award Committee fully antici-

pates an even greater response in 2007, and FASEB is

grateful for their efforts devoted to an intense review

of these highly accomplished scientists.

F A S E B C o m m i t t e e s

Excellence in Science Award

Winners 2006

Marilyn Farquahr has been

Professor and Chair of

Cellular and Molecular

Medicine at the University

of California San Diego

since 1990 and previously

held positions as Professor

of Pathology at the UCSF

School of Medicine,

Professor of Cell Biology at

Rockefeller University, and Sterling Professor of Cell

Biology at Yale University School of Medicine. She is

recognized for her seminal work in the regulation of

protein trafficking and signaling in endocrine and

exocrine cells as well as for defining the molecular

mechanisms of glomerular filtration and pathology.

She has published nearly 300 papers in prestigious

journals and has trained over 40 postdoctoral and

graduate students. She is a member of the National

Academy of Sciences and the American Academy of

Arts and Sciences and has received the Wilson Medal

of the American Society of Cell Biologists, the Homer

Smith Medal of the American Society of Nephrology,

the Distinguished Scientist Medal of the EMSA, the

Chancellor’s Award for Excellence in Research

(UCSD), the Rous-Whipple Award of the American

Society for Investigative Pathology, and the A. N.

Richards Award for Excellence in Research from the

International Society of Nephrology. She has served

as President of the American Society of Cell Biology,

on the editorial boards of the Journal of Cell Biology,

the Journal of Clinical Investigation and Molecular

Medicine, and currently serves on the Editorial Board

of Molecular Biology of the Cell and as Associate

Editor of the Journal of Histochemistry and

Cytochemistry. She received her Ph.D. from the

University of California Berkeley and San Francisco,

and did postdoctoral work at the University of

California San Francisco and the Rockefeller

University. Her current work is focused on studying

the spatial regulation of signaling mediated by protein

trafficking and targeting along the exocytic and endo-

cytic pathways with emphasis on novel functions of G

proteins on intracellular membranes.

Elaine Fuchs is currently

Rebecca C. Lancefield

Professor and Head of the

Laboratory of Mammalian

Cell Biology and

Development, Rockefeller

University, as well as an

Investigator for the Howard

Hughes Medical Institute.

She is a world leader in

skin biology and its human genetic disorders, which

include skin cancers and life-threatening genetic syn-

dromes such as blistering skin disorders. Early in her

scientific career, she focused on the molecular mech-

anisms that underlie the development and differentia-

tion of the epidermis and its appendages from multi-

potent stem cells. Throughout her studies, she has

continually used the basic biology she has uncovered

to elucidate how perturbations of these mechanisms

result in disease. She has systematically applied

molecular and genetic approaches to these problems.

In doing so, she pioneered the use of “reverse genet-

ics,”a then unconventional but now textbook

approach to understanding how proteins function

and then work up to the human diseases they cause

when defective. She initially conceived and applied

this strategy to elucidate the functions and genetic

basis of the first intermediate filament disorder, now a

group of nearly 20 related but distinct human disor-

ders. Recently, she has applied her findings to devise

creative approaches for identifying, isolating, and char-

acterizing the multipotent stem cells from skin and

determining how they respond to various external

cues to select their fates to become hair follicles,

sebaceous glands, or epidermis. In addressing the

problem of the progression from stem cell to tissue,

her laboratory now investigates how cells coordinate

changes in transcription, cell polarity, adhesion, and

18

Marilyn Farquahr, Ph.D.

F A S E B C o m m i t t e e s

Elaine Fuchs, Ph.D.

cytoskeletal dynamics. She is widely credited for

bringing dermatology into modern science and has

published over 200 papers, mostly in high profile sci-

entific and medical journals. She received her Ph.D.

in Biochemistry from Princeton University in 1977.

She conducted postdoctoral research at the

Massachusetts Institute of Technology in the laborato-

ry of Howard Green. In 1980, she joined the faculty at

the University of Chicago. When she left Chicago to

accept a position at The Rockefeller University in

2002, she was the Amgen Professor of Basic Sciences.

Among her many awards and honors are the

Presidential Young Investigator Award, the Richard

Lounsbery Award from the National Academy of

Sciences, the Novartis-Drew Award for Biomedical

Research, and the Dickson Prize in Medicine. She is a

member of the National Academy of Sciences, the

Institute of Medicine of the National Academy of

Sciences, and the American Academy of Arts and

Sciences. She holds an honorary doctorate from Mt.

Sinai-New York University School of Medicine, is a

past President of the American Society of Cell

Biology, and was recently elected to the American

Philosophical Society.

Excellence in Science Award

Committee Members

Marianne Wessling-Resnick (ASN)

Siribhinya Benyajati (APS)

Margaret Offermann (ASBMB)

Laura Nisenbaum (ASPET)

Nancy L.Thompson (ASIP)

Mercedes Rincón (AAI)

Maya Sieber-Blum (AAA)

Lisa M. Gloss (Protein)

Catherine E. Krull (SDB)

Nancy D. Denslow (ABRF)

Jane B. Lian (ASBMR)

Suzanne D. Conzen (ASCI)

Mary B. Zelinski (SSR)

Henry M. Kronenberg (TES)

Judith L.Turgeon (TES)

19

Robert Nussbaum (ASHG)

Florence Haseltine (SGI)

Karen M.Vasquez (EMS)

Anne B. Loucks (ACSM)

Guy C. Fogleman – Executive Director (FASEB)*

*Ex-officio, non-voting

FINANCE COMMITTEE,

Kenneth Mann, Treasurer and Chair

FASEB operations and the return from its invested

assets continued to improve in 2006. The reserves

contributed almost $550K in interest and dividend

income, after subtracting management expenses, and

recorded over $1M in realized gains. The contribu-

tions from the campus support services,The FASEB

Journal, and the FASEB Summer Research Conference

program all exceeded budget. While our progress

leasing space in the Lee Building has been slower

than hoped for (primarily due to use restrictions), we

remain optimistic that we will fill a majority of the

available space in 2007.

During 2006, the Finance Committee:

• Evaluated the final report and management recom-

mendations from an independent study commis-

sioned to evaluate FASEB’s compensation manage-

ment plan. The study reviewed benchmark positions

against survey data for like organizations and includ-

ed a direct survey.

• Approved the final report and selected recommen-

dations from the Finance Committee Task Force on

Long-Term Fiscal Issues.

• Received detailed presentations, including program

and financial history, on the reserves,The FASEB

Journal, and the Summer Research Conference pro-

grams. The committee discussed program chal-

lenges and opportunities for these significant finan-

cial contributors.

F A S E B C o m m i t t e e s

• Executed a swap contract to effectively fix the inter-

est rate on the bonds used to finance the East Wing

and parking structure construction.

• Recommended to the Board, and received approval

for, a reserve designation for the future renovation

needs of the Beaumont campus.

• Initiated an ad hoc committee of the Finance

Committee to engage society officers in an effort to

pool experience with respect to financial policies

and advisors.

During the next year, we anticipate continuing

face-to-face reviews of the business operations of the

Federation including activities in finances and oppor-

tunities. As this information is developed it is antici-

pated that the Committee will be able to provide

longer term financial projections to the Board.

The Finance Committee recognizes Tony Fragnito, Guy

Fogelman, and the FASEB staff for their diligence in

assisting the Committee.

Finance Committee Members

Kenneth G. Mann (ASBMB)

Ann C. Bonham (APS)

Charles O. Rutledge (ASPET)

Stanley Cohen (ASIP)

Fred D. Finkelman (AAI)

Duane E. Haines (AAA)

Bruce D. Murphy (SSR)

Kathryn W.Tosney. (SDB)

Peter A.Ward (ASIP)

Gerald L. Hazelbauer (Protein)

Terry R. Brown (TES)

James C. Rose (SGI)

Jeffrey L. Schwartz (EMS)

Anthony T. Fragnito – Deputy Executive

Director and Chief Financial Officer (FASEB)*

Guy C. Fogleman – Executive Director (FASEB)*

*Ex-officio, non-voting

PUBLICATIONS AND COMMUNICATIONS COMMITTEE,

David M. Klurfeld,Chair

The FASEB Publications and Communications

Committee (PCC) met in May 2006. The meeting cov-

ered issues from the new online interface for the

FASEB Directory of Members to cross-committee par-

ticipation between the PCC and the FASEB Finance

Committee. A significant portion of the meeting was

spent on items relating to The FASEB Journal. Gerald

Weissmann, the journal’s new Editor-in-Chief, delivered

his first report to the committee. The PCC also heard

reports on journal business and production issues

from the Office of Publications staff. The decision to

discontinue the FJ Express method of publishing, as

recommended by the Editor-in-Chief and supported

by the Editorial Board, was approved by the PCC.

The Editorial Advisory Committee, a subcommittee of

the PCC formed in 2005, changed leadership from

Sam Enna to Tom Baldwin at the May meeting. The

advisory committee was engaged throughout 2006

reviewing editorials and other up-front material for

the journal.

The PCC reviewed and approved a revision to the edi-

torial policies for The FASEB Journal in August. The

PCC was also called upon in November to review an

allegation of misconduct.

PCC Members

David M. Klurfeld (ASN)

Eileen M. Hasser (APS)

Peter A. Rubenstein (ASBMB)

Edward T. Morgan (ASPET)

Jon S. Morrow (ASIP)

Thomas R. Malek (AAI)

Donald A. Fischman (AAA)

Thomas O. Baldwin (Protein)

Sally A. Moody (SDB)

Clive A. Slaughter (ABRF)

Suzanne M. Jan de Beur (ASBMR)

20

F A S E B C o m m i t t e e s

Kai W.Wucherpfennig (ASCI)

Alan L. Johnson (SSR)

Lorraine Fitzpatrick (TES)

Miriam G. Blitzer (ASHG)

Phyllis C. Leppert (SGI)

Robert H. Heflich (EMS)

Scott Markel (ISCB)

Andrew J.Young (ACSM)

Linda C. Giudice (SGI)

Gerald Weissmann – Editor-in-Chief*

Guy C. Fogleman – Executive Director (FASEB)*

*Ex-officio, non-voting

FASEB SUMMER RESEARCH CONFERENCE ADVISORY

COMMITTEE,William A. Muller, Chair

Thirty-three FASEB Summer Research Conferences

were scheduled in 2006.The FASEB Summer

Research Conference Advisory Committee reviews

and selects conferences from proposals submitted by

member and nonmember organizers. Every effort is

made to avoid duplication of conferences. Emphasis

is on cutting-edge research, with prominent scientists

in each field making presentations to attendees who

are heavily engaged in research or are in ancillary

fields where an accurate understanding of allied sci-

entific advances is important. Postdoctoral candi-

dates are also encouraged to participate in the con-

ferences. Attendees are selected by the organizers on

the basis of their probable contributions to science.

Conferences were held at the Vermont Academy,

Saxtons River,Vermont; Snowmass Village, Snowmass,

Colorado; the Omni Tucson Resort,Tucson,Arizona;

and the Hyatt Grand Champions Resort, Indian Wells,

California. Total attendance for all conferences was

3,934 with an average of 124 persons per conference.

Twenty-nine percent of the participants were from

outside the U.S.

21

2006 FASEB Summer Research

Conferences

• AMPK: Impact on Mammalian Metabolism and

Disease (Cosponsored by The Endocrine Society)

• Amyloid Fibril Formation, Protein Misfolding and

Aggregation: Chemistry, Physiology and Disease

• Biological Methylation

• Calcium and Cell Function

• Dynamic Structure of the Nuclear Hormone

Receptors (Cosponsored by The Endocrine Society)

• Folic Acid,Vitamin B12 and One Carbon Metabolism

• Liver Growth, Development and Disease

• Lung Surfactant: Cellular and Molecular Biology

• Lymphocytes and Antibodies

• Mechanisms of Action of Steroid Hormones;

Integration of Membrane- and Nucleus-Mediated

Effects (Cosponsored by The Endocrine Society)

• Mechanisms of Plant Development

• Membrane Organization by Tetraspanins and Small

Multi-Transmembrane Proteins

• Microbial Polysaccharides of Medical Agricultural

and Industrial Importance

• Molecular Biology of Intestinal Lipid Transport and

Metabolism

• Molecular Biophysics of Cellular Membranes

• Neural-Immune Interaction: Pathological

Mechanisms and Repair

• Nucleic Acid Enzymes

• Phospholipases

• Post-transcriptional Control of Gene Expression:

Mechanisms of mRNA Decay

• Poxviruses

• Protein Folding in the Cell

• Protein Lipidation, Signaling and Membrane Domain

• Protein Phosphatases

• Regulation and Function of Small GTPases

• Retinal Neurobiology and Visual Processing

• Retinoids

• Smooth Muscle

• Trace Element Micronutrients: Integrating Basic and

Applied Research

F A S E B C o m m i t t e e s

• Transcriptional Regulation During Cell Growth,

Differentiation, and Development

• Transplantation Immunology

• Ubiquitin and Cellular Regulation

• Virus Assembly

• Yeast Chromosome Structure, Replication and

Segregation

Summer Research Conference

Advisory Committee Members

William A. Muller (ASIP)

Kathryn E. Meier (APS)

George M. Carman (ASBMB)

Jack Bergman (ASPET)

Douglas G. Burrin (ASN)

Donna M. Paulnock (AAI)

A.Wayne Vogl (AAA)

Thomas O. Baldwin (Protein)

Gerald B. Grunwald (SDB)

Satya P. Yadav (ABRF)

Robert D. Blank (ASBMR)

Volker Hans Haase (ASCI)

Asgerally T. Fazleabas (SSR)

Douglas M. Stocco (SSR)

Keith L. Parker (TES)

Douglas A. Marchuk (ASHG)

Laura T. Goldsmith (SGI)

Laura J. Niedernhofer (EMS)

Michael Joyner (ACSM)

Guy C. Fogleman – Executive Director (FASEB)*

*Ex-officio, non-voting

MEMBERSHIP COMMITTEE, Mark O. Lively, Chair

The Membership Committee is an ad hoc committee

of the Board charged to make recommendations

regarding membership in FASEB. Specifically, the

charge to the Committee is to: 1) make recommenda-

tions regarding the FASEB Strategic Plan regarding

those specific sections that deal with attracting new

member organizations to FASEB; 2) develop a set of

criteria for new members; 3) develop a list of poten-

tial organizations that FASEB could approach; and 4)

review existing and future applications for FASEB

membership as processed by the Executive Office,

and make recommendations to the Board.

In 2006, the Committee recommended the following

Criteria for Society Membership to the Board: “FASEB

members are scientific societies dedicated to the

advancement of research and teaching in experimen-

tal biology and biomedicine. The individual members

of the societies are engaged in research and educa-

tion in the biological and biomedical sciences.” Four

societies were contacted during 2006 regarding possi-

ble membership in FASEB. This outreach has not yet

resulted in new prospects for FASEB membership.

It is anticipated that the Membership Committee will

continue to prioritize additional societies for possible

membership in FASEB and to refine the rights and

responsibilities of membership.

Membership Committee Members

Mark O. Lively (ABRF)

Leo T. Furcht – FASEB President

Robert E. Palazzo (ASBMB)

Gregory G. Germino (ASCI)

Jim Rose (SGI)

Martin Frank (APS)

Neil Granger (APS)

Guy C. Fogleman – Executive Director (FASEB)

Anthony T. Fragnito – Deputy Executive Director and

Chief Financial Officer (FASEB)

Howard H. Garrison – Deputy Executive Director for

Policy; Director, Office of Public Affairs (FASEB)

22

F A S E B C o m m i t t e e s

STRATEGIC PLANNING OVERSIGHT COMMITTEE,

Peter A.Ward, Chair

The Strategic Planning Oversight Committee (SPOC)

was developed to provide a review of the objectives

of the Strategic Plan and to report progress to the

Board in meeting those objectives. The Committee

worked closely with the Membership Committee, the

Finance Committee, the Executive Committee, and

the Public Affairs Committee to analyze and make

recommendations regarding FASEB’s future growth,

governance, business model, and biomedical science

advocacy agenda. SPOC, with the support of the

Executive Committee, initiated two task forces: a

Public Affairs Task Force and a Long Term Financial

Issues Task Force. These task forces reported to SPOC

and then to the Board on their recommendations.

SPOC, having successfully completed its major tasks,

was formally disbanded at the December 2006 FASEB

Board meeting.

SPOC Members

Peter A.Ward (ASIP)

Leo T. Furcht – FASEB President

Robert E. Palazzo – FASEB President-Elect

Bruce R. Bistrian – FASEB Past President

Christine K. Carrico (ASPET)

Avrum I. Gotlieb (ASIP)

Mary Lou King (SDB)

John Hawley (ASCI)

Wylie W.Vale (TES)

Garry R. Cutting (ASHG)

George Hoffmann (EMS)

John Smith – Vice President for Science Policy

Richard B. Marchase – Past Vice President for

Science Policy

Mark Lively – Vice President-Elect for Science Policy

Guy C. Fogleman – Executive Director (FASEB)

Anthony T. Fragnito – Deputy Executive Director

and Chief Financial Officer (FASEB)

Howard H. Garrison – Deputy Executive Director for

Public Affairs; Director, Office of Public Affairs

(FASEB)

F A S E B C o m m i t t e e s

23

24

It is just over a year now since a new Editorial Board assumed responsibility for The FASEB

Journal, and we report progress in four areas.

Publishing Performance

In July, responding to an Editorial Board decision, we changed our practice of printing part

of our content as summary versions of fuller manuscripts available online (FJ Express). We

have now reverted to the classic model of a research journal that prints only complete arti-

cles (with e-publication on acceptance after full review). Thanks to this switch, a sparkling

staff, an active, internationally known Editorial Board, and a legion of devoted reviewers,

both the kinetics and demographics of the journal have changed.

Despite decreasing the total number of titles published, we now receive close to 200 IQ

(initial query) submissions per month (vs. 117 in 2004). This rate is constant—we received

over 2000 IQs in 2006 (vs. 1583 in 2004). We have also shortened the turnaround time

between first submission and acceptance to 28 days (vs.103 days in 2004). In consequence,

the bar to publication has been raised: we now accept no more than 10% of papers submit-

ted (vs. 35% in 2004). This barrier has caused no little dismay, and elicited many comments

along the lines of Adlai Stevenson’s definition of an editor as “…a person whose business it

is to separate the wheat from the chaff, and to see that the chaff is printed.”

Scientific Excellence

The quality of our associate editors and board has attracted attention internationally, and

each agrees that the work they review is improving with each month. We are fortunate to

have scientists on board who have founded and/or who dominate the fields in areas for

which they are responsible. These include, among many others, Judah Folkman of Harvard

University (angiogenesis), Salvador Moncada of University College London (nitric oxide),

Peter Lachmann of the University of Cambridge (complement), Jean-Pierre Changeux of the

L’Institut Pasteur, Paris (allosteric controls),Arnold Levine of Princeton University (p53 and

January 2006 January 2004

IQs submitted 186 117

Turnaround (days) 28 103

Papers accepted (last 6 months) 10% 35%

Overall size (pages) 298 223

Research articles 30 12

FJ Express articles 0 37

T h e F A S E B J o u r n a l[ ]

Gerald Weissmann, M.D.Editor-in-Chief

tumor suppression), Helen Blau of Stanford University (cell fusion), George Martin of the

University of Washington (senescence genes), Robert Goldman of Northwestern University

(intermediate filaments), and Etienne Baulieu of INSERM, Paris (RU 486 and steroid hor-

mones). The board also includes members from each society who are eminent in their

own fields. Many board members have had articles submitted from their own labs, and the

institutions at which they work are well represented in the list of articles published.

The Public Face

Thanks in part to a new design, we have attracted the notice of a new public, both on the

web and in libraries. Our covers combine striking images taken from masterpieces of sci-

entific illustration (Haeckel, Leuckart, and Pinson, for example) with short, newsworthy

captions that spell out the cover story. One cover alludes to a detailed geo/biochemical

study of the effects of olive oil on DNA damage and was accompa-

nied by a press release which was picked up by Reuters, and other

media worldwide. The journal’s Managing Editor, Cody Mooneyhan,

has been instrumental in producing and disseminating outstanding

press releases. We have issued a calendar of these covers, which has

been well received. Finally, our frank, open, and extensive editorial

positions in favor of investigator-sponsored research and evolutionary

science, our opposition to faith-based science, intelligent design, and

“alternative medicine”have attracted wide attention. They have been

covered in the columns of Science and the blogs of the Discovery

Institute, come to the attention of our colleagues at the JCI, and

brought rebuttal from the very top of the NIH. Life Science Forum,

Milestones, Book Reviews, and other features have won praise from

our readers—we have become readable.

International Impact

The distribution of our authorship is exactly that of what Thomson

Scientific describes as the world-wide publishing pattern of the “lead-

ing scientific journals in all fields.” In 2006, we received contributions

from 60 countries including the Sudan, Cote Ivoire, Congo, Uzbekistan, Iran, Serbia and

Montenegro, and Vanuatu (vs. 50 in 2004). The United States submitted a plurality, but not

a majority of the work, a fact in keeping with the worldwide patterns of today’s science.

Finally, the editors have sharpened the focus of the journal—we have rejected good work

in order to publish only the best. We recognize that much of what we turn down is indeed

good science and is the product of the latest techniques, the highest of aims, and the most

intricate work. However, the object of intricate science is not the exhibition of intricacy,

but its result. As Henry Higginson of The Atlantic Monthly once quipped “You do not put

guano on your garden that your garden may blossom guano.” We expect our garden to

bloom. n

25

2006 Submissionsa

North Americab 597 32%

Europec 799 43%

Asiad 383 21%

Anzace 50 3%

Middle Eastf 38 2%

South and Central Americag 31 2%

Africah 6 <1%

Total 2082

a43% accepted for review. bUSA: 511, Canada: 86; cUnited Kingdom: 181, Germany:171, France: 115, Italy: 109, Spain: 62, The Netherlands: 35, Switzerland: 32,Belgium: 27, Sweden: 25 Austria: 19, Denmark: 15, Finland: 12, Greece: 11, Portugal:10, Hungary: 8, Norway: 5, Poland: 5, Ireland: 4, Czech Republic: 3, Russia: 2,Luxembourg: 1, Kyrgystan: 1, Uzbekistan: 1; dChina: 121, Japan: 112 , Korea: 78,Hong Kong: 15, Taiwan: 29, India: 15, Singapore: 13; eAustralia: 42, New Zealand: 5;fIsrael: 33, Lebanon: 1, Iran: 3, Jordan: 1; gBrazil: 11 Mexico: 3 Chile: 2, Venezuela: 2;hSouth Africa: 1, Tanzania: 2, Sudan: 1, Ivory Coast: 1, Congo: 1.

T h e F A S E B J o u r n a l

FASEB DEPARTMENTS

Executive Office

Guy C. Fogleman, Executive Director

Anthony T. Fragnito, Chief Financial Officer and

Deputy Executive Director

Howard Garrison, Deputy Executive Director for Policy

Office of Public Affairs

Howard Garrison, Director

Office of Publications

Jennifer L. Pesanelli, Director

Office of Scientific Meetings and Conferences

Geri Swindle, Director

Managed Society Services

Debra L.Weinstein, Director

Accounting and Financial Reporting

David L. Craven, Manager

Contract Financial Services

Iris V. Stratton,Assistant Director

Office of Production and Postal Services

Richard A. Dunn, Director

Information Technology

Guy Riso, Director

Human Resources

Maureen Murphy, Director

Buildings and Grounds

Jeffrey L.Yocum, Facilities Manager

Dues and Subscription Services

Eleanor B. Peebles, Manager

Career Resources and Minority

Access to Research Careers

Jacquelyn Roberts, Manager

FASEB CLIENTS

In addition to the FASEB Member Societies, many

other nonprofit organizations benefit from the prod-

ucts and services provided by FASEB departments.

In 2006, our clients included:

Academy of Certified Hazardous Materials Managers

The American Board of Genetic Counseling

American Board of Medical Genetics

American College of Medical Studies

American College of Toxicology

American Society of Animal Sciences

American Society for Matrix Biology

American Society for Virology

Association for Molecular Pathology

Association for Psychological Type International

Association of Pathology Chairs

Association for Research in Vision and Ophthalmology

Environmental Partners

Genetics Society of America

Inflammation Research Association

International Energy Agency Hydrogen Implementing

Agreement

International Society for Analytical Cytology

International Society for Biological and Environmental

Repositories

International Society for Interferon and Cytokine Research

Institute of Mathematical Statistics

Life Sciences Research Office

National Association of Orthopedic Technologists

North American Vascular Biology Organization

Pan American League of Associations for Rheumatology

Protein Data Bank

Ribonucleic Acid Society

Society for Free Radical Biology and Medicine

Society of Biological Inorganic Chemistry

Society of Chinese Bioscientists in America

Society for Leukocyte Biology

F A S E B

26

[ ]

F i n a n a c i a l R e p o r t 2 0 0 6[ ]

The Statement of Financial Position, Statement of Activities and Statement of Cash Flows

are reproduced on the following pages. These statements summarize the more detailed

financial statements audited by Tate and Tryon, P.C. A copy of the financial statements is

available upon request from the Office of the Chief Financial Officer and Deputy Executive

Director.

As required by Generally Accepted Accounting Principles (GAAP), the Federation reports

information regarding its financial position and activities according to three classes of net

assets: unrestricted, temporarily restricted and permanently restricted.

The majority of Federation activities and net assets are unrestricted and controlled by the

Federation Board.

The Federation has adopted Statement of Financial Accounting Standards (SFAS) 124

which requires debt and equity securities be reported at market value. The market value of

investments held by the Federation during the year increased $1,877,353 to a total of

$18,498,889. The market value of investments on December 31, 2005 totaled $16,621,536.

Statement of Financial Position

This statement presents the assets, liabilities and net assets of the Federation on December

31, 2006. The net assets, the difference between assets and liabilities, are $21,359,185. This

represents the accumulated net operating results of the organization during its 90+-year

history.

Investments of $18,498,889 are diversified in U.S.Treasury bills and notes, commercial

paper, commercial bonds, and common stock. The Federation has two major unrestricted

investment accounts—The Program Reserve and the Depreciation Reserve. The Program

Reserve provides financial security in the event of revenue failure or unanticipated cata-

strophic emergency, to serve as a hedge against the outstanding mortgage on the

Federation’s property and to support operations. The Depreciation Reserve provides for

capital improvements, renovations, and repairs or purchases of major equipment with a

unit price exceeding $5,000. In November 2006, the Federation purchased a swap against

interest rate risk associated with the variable rate loan from SunTrust bank. This swap effec-

tively fixes the interest rate on this debt for the remaining term of the bonds at 3.60%

27

The other significant asset of the Federation is the net investment of $17,434,000 in the build-

ings, grounds, furniture and equipment on the Beaumont campus, home to the Federation, its

constituent societies and other scientific and educational societies located on the campus.

Liabilities totaling $18,168,221 include amounts owed to vendors for products and services

received and the working capital credit line totaling $1,600,000, revenue received in 2006 but

applicable to programs to be conducted in 2007of $808,261, amounts owed to employees under

the deferred compensation plan of $431,459, and the building financing payable to SunTrust

bank for $12,725,000.

Statement of Activities

The Statement of Activities covers the 12 months for the calendar year ending December 31,

2006 and identifies the sources of revenue and expense. The financial plan adopted by the

Federation Board required the Board to set a rate for annual dues paid to the Federation by the

member societies. The dues rate for 2006 was $13 per society member with minimum dues of

$10,000 and a maximum of $125,000 per Society.

The accompanying statement shows total revenues of $18,383,243, including $613,568 of divi-

dends and interest and $1,013,548 of realized gains on investments and $51,728 of unrealized

gain on investments, and expenses of $17,928,056.This resulted in a net income of $1,520,463.

28

F i n a n a c i a l R e p o r t

$10,000,000

$8,000,000

$6,000,000

$4,000,000

$2,000,000

0Member

DuesCampus SupportServices

ProgramServices

Net ReserveEarnings

$10,000,000

$8,000,000

$6,000,000

$4,000,000

$2,000,000

0Core

Functions(OPA &

Leadership)

Campus SupportServices

ProgramServices

Net G&A

S O U R C E S O F R E V E N U E

A C T U A L E X P E N S E

2006 2005

S t a t e m e n t o f F i n a n c i a l Po s i t i o n

D e c e m b e r 3 1 , 2 0 0 6 2 0 0 5

ASSETS

Cash and cash equivalents - Note B $ 1,343,293 $ 1,349,089Investments - Notes B & C 18,064,476 16,201,985Accounts receivable

Trade receivables 365,140 409,841Government contracts and accounts 134,149 238,684Member societies and custodial grants - Note E 1,406,464 1,359,664Note receivable - Note J 150,000 100,000

Prepaid expenses 195,472 182,392 Interest rate cap contract - Note D 2,954 17,581Investment held to fund deferred compensation - Note H 431,459 401,970 Property and equipment

Land, building, and building improvements 23,696,125 23,480,159Furniture and equipment 3,017,556 2,983,654Less: accumulated depreciation (9,279,682) (8,590,845)

Net property and equipment 17,433,999 17,872,968

TOTAL ASSETS $ 39,527,406 $38,134,174

LIABILITIES AND NET ASSETS

LIABILITIES Accounts payable and accrued expenses $ 1,043,700 $ 1,060,021 Deferred revenue 808,261 854,195 Amounts held for member societies and custodial accounts - Note E 176,422 154,863 Amounts held for custodial funds from managed meetings - Note E 1,196,987 1,327,840 Deferred compensation - Note H 431,459 401,970Interest rate swap agreement - Note D 186,392 - Notes payable - economic development revenue bonds - Note I 12,725,000 13,000,000 Notes payable - line of credit - Note I 1,600,000 1,500,000

TOTAL LIABILITIES 18,168,221 18,298,889

NET ASSETS

Unrestricted 21,247,986 19,727,523Temporarily restricted - Note F 86,699 83,262Permanently restricted - Note G 24,500 24,500

TOTAL NET ASSETS 21,359,185 19,835,285

TOTAL LIABILITIES AND NET ASSETS $39,527,406 $38,134,174

29

F i n a n a c i a l R e p o r t

30

S t a t e m e n t o f A c t i v i t i e s

Ye a r E n d e d D e c e m b e r 3 1 , 2 0 0 6 2 0 0 5

UNRESTRICTED ACTIVITIES

REVENUE

Program services

Summer Research Conferences $ 4,907,069 $ 4,089,598

The FASEB Journal and Directory 2,263,987 2,200,361

MARC Program 1,581,769 1,445,299

Career Resources 126,127 136,960

Campus support services - Note E 7,517,582 6,844,601

Core functions 755,386 771,203

Investment income - Note C 613,568 526,557

General services 539,838 675,117

Net assets released from restrictions 77,917 38,948

Total unrestricted revenue 18,383,243 16,728,644

EXPENSE

Program services

Summer Research Conferences 4,314,598 3,650,958

MARC Program 1,581,775 1,445,308

The FASEB Journal and Directory 1,195,705 1,202,481

Career Resources 57,342 103,334

Campus support services - Note E 7,186,163 6,583,362

Core functions 1,207,532 1,333,544

Total program services 15,543,115 14,318,987

Supporting services

Investment expense 68,767 67,556

General and administrative 2,316,174 2,301,708

Total supporting services 2,384,941 2,369,264

Total expense 17,928,056 16,688,251

Change in unrestricted net assets before net gain on investments and change in interest swap valuation 455,187 40,393

Net gain on investments - Note C 1,251,668 158,682

Loss on fair value of interest swap agreement - Note D (186,392) -

Change in unrestricted net assets 1,520,463 199,075

TEMPORARILY RESTRICTED ACTIVITIES

Contributions 80,697 76,231

Investment income - Note C 657 498

Net assets released from restrictions (77,917) (38,948)

Change in temporarily restricted net assets 3,437 37,781

CHANGE IN NET ASSETS 1,523,900 236,856

Net assets, beginning of year 19,835,285 19,598,429

NET ASSETS, END OF YEAR $ 21,359,185 $ 19,835,285

F i n a n a c i a l R e p o r t

31

S t a t e m e n t o f C a s h F l o w s

Ye a r E n d e d D e c e m b e r 3 1 , 2 0 0 6 2 0 0 5

CASH FLOWS FROM OPERATING ACTIVITIESChange in net assests $ 1,523,900 $ 236,856Adjustments to reconcile change in net assests to net cash

provided by operating activities:Depreciation and amortization 735,485 683,370 Net gain on investments (1,251,806) (158,457)Loss on fair value of interest swap agreement 186,392 -Changes in assests and liabilities:

Accounts receivable 52,436 (125,235) Prepaid expenses (13,080) 86,354 Accounts payable and accrued expenses (16,321) 111,196Deferred revenue (45,934) 209,607 Amounts held for member societies and custodial accounts 21,559 3,381 Amounts held for custodial funds from managed accounts (130,853) 150,273

Total adjustments (462,122) 960,489Net cash provided by operating activities 1,061,778 1,197,345

CASH FLOWS FROM INVESTING ACTIVITIESNet purchases of investments (617,708) (130,647)Purchase of property and equipment (274,866) (702,483)Net cash used in investing activities (892,574 (833,130)

CASH FLOWS FROM FINANCING ACTIVITIESProceeds from the line of credit 100,000 350,000Principal payments on the economic development revenue bonds (275,000) -Net cash (used in) provided by financing activities (175,000) 350,000

NET (DECREASE) INCREASE IN CASH AND CASH EQUIVALENTS (5,796) 714,215Cash and cash equivalents, beginning of year 1,349,089 634,874

CASH AND CASH EQUIVALENTS, END OF YEAR $ 1,343,292 $ 1,349,089

SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATIONCash paid during the year for interest $ 492,081 $ 350,973Cash paid during the year for income taxes $ 39,500 -

F i n a n a c i a l R e p o r t

32

M e m b e r S o c i e t i e s o f t h e F e d e r a t i o n

THE AMERICAN PHYSIOLOGICAL SOCIETY – APS

Founded: December 30, 1887

Founding Member of FASEB: 1912

Mission: The APS provides leadership in the life

sciences by promoting excellence and innovation in

physiological research and education and by provid-

ing information to the scientific community and to

the public.

President: Dale Benos, Dept. of Physiology and

Biophysics,University of Alabama at Birmingham

Executive Director: Martin Frank

Membership: 9,700

Publications:

American Journal of Physiology (AJP) Consolidated

AJP – Cell Physiology

AJP – Endocrinology and Metabolism

AJP – Gastrointestinal and Liver Physiology

AJP – Lung Cellular and Molecular Physiology

AJP – Heart and Circulatory Physiology

AJP – Regulatory, Integrative and Comparative

Physiology

AJP – Renal Physiology

Journal of Applied Physiology

Journal of Neurophysiology

Physiological Reviews

Physiological Genomics

Physiology

Advances in Physiology Education

The Physiologist

APS Journal Legacy Content

Website: www.the-aps.org

2006 Meetings:

Annual Meeting with Experimental Biology 2006,

San Francisco, California,April 1–5; APS Intersociety

Meeting: Comparative Physiology 2006: Integrating

Diversity,Virginia Beach, Virginia, October 8–11;

APS Conference: APS Physiological Genomics and

Proteomics of Lung Disease, Fort Lauderdale, Florida,

November 2–5

AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR

BIOLOGY – ASBMB

Founded: December 26, 1906

Founding Member of FASEB: 1912

Mission: Promoting understanding of the molecular

nature of life processes.

President: Heidi Hamm, Department of

Pharmacology,Vanderbilt University School of

Medicine, Nashville,Tennessee

Executive Director: Barbara A. Gordon

Membership: 11,700

Publications:

The Journal of Biological Chemistry

JBC Minireview Compendium

Molecular and Cellular Proteomics

Journal of Lipid Research

Biochemistry and Molecular Biology Education

ASBMB Today

Website: www.asbmb.org

2006 Meeting:

ASBMB, San Francisco, California,April 1–5

[ ]

32

33

AMERICAN SOCIETY FOR PHARMACOLOGY AND

EXPERIMENTAL THERAPEUTICS – ASPET

Founded: December 28, 1908

Founding Member of FASEB: 1912

Mission: The Society’s purpose is to promote the

advancement of the sciences of pharmacology and

experimental therapeutics and to facilitate the inter-

change of information among investigators who are

engaged in research in those fields by organizing

scientific meetings, publishing journals, and engaging

in other activities that advance the discipline.

President: Elaine Sanders-Bush,Vanderbilt

University, Nashville,Tennessee

Executive Director: Christine K. Carrico

Membership: 4,700

Publications:

The Pharmacologist

Journal of Pharmacology and Experimental

Therapeutics

Pharmacological Reviews

Molecular Pharmacology

Drug Metabolism and Disposition

Molecular Interventions

Website: www.aspet.org

2006 Meeting: Annual Meeting with Experimental

Biology 2006, San Francisco, California,April 1–5

AMERICAN SOCIETY FOR INVESTIGATIVE

PATHOLOGY-ASIP

Founded: December 1900

Member of FASEB: since1913

Mission: ASIP is a society of biomedical scientists

who investigate mechanisms of disease. Investigative

pathology is an integrative discipline that links the

presentation of disease in the whole organism to its

fundamental cellular and molecular mechanism. It

uses a variety of structural, functional, and genetic

techniques, and ultimately applies research findings

to the diagnosis and treatment of diseases. ASIP

advocates for the practice of investigative pathology

and fosters the professional career development and

education of its members.

President: Peter M. Howley, Department of Pathology,

Harvard Medical School, Boston, Massachusetts

Executive Director: Mark E. Sobel

Membership: 2,200

Publications:

The American Journal of Pathology

The Journal of Molecular Diagnostics

ASIP Pathways

Pathology: A Career in Medicine

Website: www.asip.org

2006 Meetings: Annual Meeting with Experimental

Biology 2006, San Francisco, California,April 1–5;

ISBER (Division of ASIP) Annual Meeting, Bethesda,

Maryland,April 30–May 2

M e m b e r S o c i e t i e s o f t h e F e d e r a t i o n

2

AMERICAN SOCIETY FOR NUTRITION – ASN

Founded: September 27, 1928

Member of FASEB: since 1940

Mission: To develop and extend knowledge of

nutrition of all species through fundamental, multi-

disciplinary, and clinical research; facilitate contact

among investigators in nutrition, medicine, and relat-

ed fields of interest; support the dissemination and

application of nutrition science to improve public

health and clinical practice worldwide; promote

graduate education and training of physicians in

nutrition; provide reliable nutrition information to

those who need it; and advocate for nutrition

research and its application to development and

implementation of policies and practices related to

nutrition.

President: Stephanie Atkinson, McMaster University

Faculty of Health Science, Hamilton, Ontario, Canada

Executive Director: John Courtney

Membership: 3,000

Publications:

American Journal of Clinical Nutrition

Journal of Nutrition

Nutrition Notes

Website: www.nutrition.org

2006 Meeting: Annual Meeting with Experimental

Biology 2006, San Francisco, California,April 1–5

THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS – AAI

Founded: June 19, 1913

Member of FASEB: since 1942

Mission: The AAI is an association of professionally

trained scientists dedicated to advancing the knowl-

edge of immunology and its related disciplines, foster-

ing the interchange of ideas and information among

investigators, and addressing the potential integration

of immunologic principles into clinical practice. AAI

serves its members by providing a center for the dis-

semination of information relevant to the field and its

practices such as educational and professional

opportunities, scientific meetings, membership

derived issues and opinions, and important social

and political issues.

President: Lewis L. Lanier, University of California,

San Francisco

Executive Director: M. Michele Hogan

Membership: 6,500

Publications:

The Journal of Immunology

AAI Newsletter

Website: www.aai.org

2006 Meeting: Immunology 2006, 93rd AAI Annual

Meeting, Boston, Massachusetts, May 12–16

34

M e m b e r S o c i e t i e s o f t h e F e d e r a t i o n M e m b e r S o c i e t i e s o f t h e F e d e r a t i o n

2

AMERICAN ASSOCIATION OF ANATOMISTS – AAA

Founded: September 17, 1888

Member of FASEB: since 1993

Mission: The purpose of the Association shall be the

advancement of anatomical sciences.

President: Kathy K. H. Svoboda, Baylor College of

Dentistry, Department of Biomedical Sciences,

Dallas,Texas

Executive Director: Andrea Pendleton

Membership: 1,800

Publications:

Developmental Dynamics

The Anatomical Record

The New Anatomist

AAA Newsletter

Website: www.anatomy.org

2006 Meeting: Annual Meeting with Experimental

Biology 2006, San Francisco, California,April 1–5

THE PROTEIN SOCIETY

Founded: February 11, 1986

Member of FASEB: since 1995

Mission: The Protein Society is the leading interna-

tional society devoted to furthering research and

development in protein science. The purpose of the

Society is to provide national and international

forums to facilitate communication, cooperation, and

collaboration with respect to all aspects of the study

of proteins. In support of these goals, the Society also

publishes Protein Science, the premier journal in the

field. Members have an opportunity to actively par-

ticipate in the emerging fields of protein including

proteomics, bioinformatics, structural biology, and

computational biology as they pertain to proteins at

the molecular and cellular level. The Protein Society

members represent academia, industry, government,

and nonprofit institutions from around the world.

President: Jeffery W. Kelly,The Scripps Research

Institute, La Jolla, California

Executive Officer: Cynthia A.Yablonski

Membership: 2,400

Publications:

Protein Science

Newsletter

Website: www.proteinsociety.org

2006 Meeting: 20th Symposium, San Diego,

California,August 5–9

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AMERICAN SOCIETY FOR BONE AND MINERAL RESEARCH

– ASBMR

Founded: 1977

Member of FASEB: since 1997

Mission: The ASBMR is a professional, scientific, and

medical society established to promote excellence in

bone and mineral research, to foster integration of

basic and clinical science, and to facilitate the trans-

lation of that science to health care and clinical

practice. Key objectives to achieve these goals

include the nurturing and development of future

generations of basic and clinical scientists, and the

dissemination of new knowledge in bone and miner-

al metabolism. The ASBMR is proactive in shaping

research and health policies based on scientific

advances in our field.

President: Steven R. Goldring, Hospital for Special

Surgery, New York, New York

Executive Director: Ann L. Elderkin

Membership: 3,900

Publications:

Journal of Bone and Mineral Research

Primer on the Metabolic Bone Diseases and Disorders

of Mineral Metabolism

ASBMRnews

Website: www.asbmr.org

2006 Meeting: ASBMR 28th Annual Meeting,

Philadelphia, Pennsylvania, September 15–19

AMERICAN SOCIETY FOR CLINICAL INVESTIGATION – ASCI

Founded: 1908

Member of FASEB: since 1998

Mission:The ASCI is an honor society of physician sci-

entists representing all disciplines of medical

science. Members are elected based upon the quality

and impact of their research, and their overall

contributions to the biomedical research community.

The Society seeks to particularly recognize physician-

scientists doing novel, creative, rigorous, and repro-

ducible research which is based on a solid founda-

tion of science and likely to stand the test of time.

The ASCI is organized and operated exclusively for

educational and scientific purposes. In furthering

these aims, the society convenes an annual

meeting and publishes the Journal of Clinical

Investigation, both of which highlight high-impact

work from a broad range of disciplines.

President: Eric R. Fearon, University of Michigan

Medical School,Ann Arbor, Michigan

Executive Director: John B. Hawley

Membership: 2,900

Publication:

The Journal of Clinical Investigation

Website: www.asci-jci.org

2006 Meeting:

Chicago, Illinois,April 28–30

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THE ENDOCRINE SOCIETY – TES

Founded: 1916

Member of FASEB: since 1999

Mission: Since its inception in 1916,The Endocrine

Society has worked to promote excellence in hor-

mone research and care of patients with endocrine

disease. With over 12,600 members from over 80

countries,The Endocrine Society is the world’s largest

and most active organization devoted to the

research, study, and clinical practice of endocrinolo-

gy. Together, the scientists, educators, clinicians, prac-

ticing MDs, nurses, and students who make up the

organization’s membership represent all basic,

applied, and clinical interests in endocrinology.

President: Leonard Wartofsky,Washington Hospital

Center,Washington, DC

Executive Director: Scott Hunt

Membership: 13,000

Publications:

Endocrinology

The Journal of Clinical Endocrinology and Metabolism

Endocrine Reviews

Molecular Endocrinology

Endocrine News

Website: www.endo-society.org

2006 Meetings: ENDO ‘06 (88th Annual Meeting),

Boston, Massachusetts, June 24–27; Clinical

Endocrinology Update, San Francisco, California,

October 6–9

THE AMERICAN SOCIETY OF HUMAN GENETICS – ASHG

Founded: 1948

Member of FASEB: since 1999

Mission: The American Society of Human Genetics

serves research scientists, health professionals and the

public by enabling its members to: share research

results at annual meetings and publish in the

American Journal of Human Genetics, advance genetic

research by advocating for research support, enhance

genetics education by preparing future

professionals and informing the public, promote

genetic services and support responsible social and

scientific policies.

President: Stephen Warren, Emory University,

Atlanta, Georgia

Executive Vice President: Joann Boughman

Executive Director: Elaine Strass

Membership: 7,000

Publications:

The American Journal of Human Genetics

Guide to North American Graduate and Postgraduate

Training Programs in Human Genetics

Solving the Puzzle–Careers in Genetics

Website: www.ashg.org

2006 Meeting: New Orleans, Louisiana, October 9–13

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SOCIETY FOR DEVELOPMENTAL BIOLOGY – SDB

Founded: 1939

Associate member of FASEB: 1996

Full member of FASEB: since 2001

Mission: The purpose of the Society is to further the

study of development in all organisms and at all lev-

els, and to represent and promote communication

among students of development.

President: Elliot Meyerowitz, Division of Biology,

California Institute of Technology, Pasadena,

California

Executive Director: Ida Chow

Membership: 2,100

Publication:

Developmental Biology

Website: www.sdbonline.org

2006 Meeting: 65th SDB Annual Meeting, University

of Michigan,Ann Arbor, Michigan, June 17–21

AMERICAN PEPTIDE SOCIETY – APEPS

Founded: 1990

Associate member of FASEB: since 1996

Mission: The purposes of the Society are to advance

and promote the knowledge of the chemistry and

biology of peptides and proteins.

President: Jane V.Aldrich, Department of Medicinal

Chemistry, University of Kansas, Lawrence, Kansas

Membership: 500

Publication:

Biopolymers (Peptide Science)

Website: www.ampepsoc.org

ASSOCIATION OF BIOMOLECULAR RESOURCE FACILITIES –

ABRF

Founded: 1988

Associate member of FASEB: since 1997

Mission: The Association of Biomolecular Resource

Facilities is an international society dedicated to

advancing core and research biotechnology labora-

tories through research,communication,and educa-

tion.

President: Jay W. Fox, University of Virginia,

Charlottesville,Virginia

Membership: 700

Publication:

Journal of Biomolecular Techniques

Website: www.abrf.org

2006 Meeting: Long Beach, California,

February 11–14

SOCIETY FOR THE STUDY OF REPRODUCTION – SSR

Founded: 1967

Associate member of FASEB: since 1998

Mission: The mission of the Society is to promote

the study of reproduction by fostering interdiscipli-

nary communication among scientists, holding con-

ferences, and publishing meritorious studies.

President: William W.Thatcher, Dept. of Animal

Sciences, University of Florida, Gainesville, Florida

Executive Officer: Judith Jansen

Membership: 2,800

Publications:

Biology of Reproduction

Biology of Reproduction Online

Biology of Reproduction Monograph Series 1; Equine

Reproduction VI

SSR Newsletter

Website: www.ssr.org

2006 Meeting: 39th Annual Meeting, Omaha,

Nebraska, July 29–August 1

M e m b e r S o c i e t i e s o f t h e F e d e r a t i o n

TERATOLOGY SOCIETY

Founded: 1961

Associate member of FASEB: since 1998

Mission: The objective of the Teratology Society is to

promote research and the exchange of ideas and

research results that reveal the causes, improve the

diagnosis and treatment, and prevent the occurrence

of abnormal development and birth defects; to com-

municate that information to physicians, public

health officials, concerned health advocacy and lay

groups and other interested parties that promote the

elimination of birth defects when possible and ame-

lioration of them when they occur; and to provide

education and training on the causes, mechanisms,

treatment and prevention of birth defects.

President: Melissa Sherman Tassinari, DABT,

Pfizer, Inc, New London, Connecticut

Vice President: Elaine M. Faustman, University of

Washington, Seattle,Washington

Executive Director: Tonia Masson

Membership: 700

Publications:

Birth Defects Research,Part A,B,and C

Newsletter

Website: www.teratology.org

2006 Meeting: 46th Annual Meeting,Tucson,

Arizona, June 24–29

SOCIETY FOR GYNECOLOGIC INVESTIGATION – SGI

Founded: 1953

Associate Member of FASEB: since 2000

Mission: The mission of the Society for Gynecologic

Investigation is to establish the scientific basis for

gynecology, obstetrics, and related disciplines by pro-

viding and promoting: 1. Leadership and excellence in

research 2. International forums for scientific

exchange 3. Mentoring, career development, and

education 4.Advocacy for research in women’s health

and reproductive science and 5. Collaboration with

academia, government, industry, and professional

organizations.

President: Gerson Weiss, Dept. OB/GYN, UMDNJ –

New Jersey Medical School, Newark, New Jersey

Executive Director: Ava A.Tayman

Membership: 1,000

Publication:

Journal of the Society for Gynecologic Investigation

Website: http://sgionline.org

2006 Meeting: Toronto, Canada, March 22–25

M e m b e r S o c i e t i e s o f t h e F e d e r a t i o n

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ENVIRONMENTAL MUTAGEN SOCIETY – EMS

Founded: 1969

Associate member of FASEB: since 2001

Mission: The Environmental Mutagen Society (EMS)

is the primary scientific society fostering research on

the basic mechanisms of mutagenesis as well as on

the application of this knowledge in the field of

genetic toxicology. EMS has seven core scientific

content areas. These are: 1. Exposure, detection and

metabolism of DNA damaging agents, 2. Responses to

DNA damage (DNA repair and recombination,

changes in gene expression, cell cycle effects), 3.

Mutational mechanisms (spontaneous and exposure

related), 4. DNA technologies, 5. Molecular epidemiol-

ogy, 6. Human health effects (developmental, cancer,

aging, genetic disease), 7.Applications: testing, regula-

tory issues and risk assessment.

President: Martina L.Veigl, Case Western Reserve

University, Cancer Center Lab, Cleveland, Ohio

President-Elect: Andrew J.Wyrobek, Lawrence

Berkeley National Laboratory, Department of

Radiation Biosciences, Berkley, California

Executive Director: Tonia Masson

Membership: 700

Publications:

Environmental and Molecular Mutagenesis

Newsletter

Website: www.ems-us.org

2006 Meeting: 37th Annual Meeting of the

Environmental Mutagen Society,Vancouver, Canada,

September 16–20

INTERNATIONAL SOCIETY FOR COMPUTATIONAL

BIOLOGY – ISCB

Founded: 1996

Associate member of FASEB: since 2003

Mission: The International Society for Computational

Biology is a scholarly society dedicated to advancing

the scientific understanding of living systems through

computation. The ISCB communicates the signifi-

cance of our science to the larger scientific communi-

ty, governments, and the public at large. The ISCB

serves a global membership by impacting govern-

ment and scientific policies, providing high quality

publications and meetings, and through distribution

of valuable information about training, education,

employment and relevant news from related fields.

President: Michael Gribskov, Dept. of Biological

Sciences, Purdue University,West Lafayette, Indiana

Executive Officer: BJ Morrison McKay

Membership: 1,800

Website: www.iscb.org

2006 Meeting:

14th Annual Intelligent Systems for Molecular Biology,

Fortaleza, Brazil,August 6–11; 4th Annual Rocky

Mountain Regional Bioinformatics Conference,

Snowmass, Colorado, December 1–3

M e m b e r S o c i e t i e s o f t h e F e d e r a t i o n

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AMERICAN ASSOCIATION OF PHYSICIANS – AAP

Founded: 1885

Member of FASEB: since 2005

Mission: The goals of its members include the pur-

suit of medical knowledge, and the advancement

through experimentation and discovery of basic and

clinical science and their application to clinical med-

icine. Each year, 55 individuals having attained excel-

lence in achieving these goals, are recognized by

nomination for membership by the Council of the

Association. Their election gives them the opportuni-

ty to share their scientific discoveries and contribu-

tions with their colleagues at the annual meeting.

President: Jerrold Olefsky, University of California,

San Diego, La Jolla, California

Membership: 1,145

2006 Meeting: Chicago, Illinois,April 28–30

AMERICAN COLLEGE OF SPORTS MEDICINE – ACSM

Founded: 1954

Member of FASEB: since 2005

Mission: The American College of Sports Medicine

promotes and integrates scientific research, educa-

tion, and practical applications of sports medicine

and exercise science to maintain and enhance physi-

cal performance, fitness, health, and quality of life.

President: J. Larry Durstine, Department of Exercise

Science, University of South Carolina, Columbia,

South Carolina

Executive Vice President: James R.Whitehead

Membership: 20,000

Publications:

Medicine & Science in Sports & Exercise

Exercise and Sport Science Reviews

Sports Medicine Bulletin

ACSM’s Health and Fitness Journal

Current Sports Medicine Reports

ACSM’s Certified e-News

ACSM FIT Society Page

Website: www.acsm.org

2006 Meetings:

53rd Annual Meeting, Denver, Colorado,

May 23–June 3

ACSM’s Health & Fitness Summit & Exposition

Orlando, Florida, April 11–14

M e m b e r S o c i e t i e s o f t h e F e d e r a t i o n

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9650 Rockville Pike, Bethesda, MD 20814

Phone 301.634.7000 • Fax 301.634.7001

www.faseb.org • info@faseb.org