Figure 7.6 Glycolysis Converts Glucose to Pyruvate

Ten enzymes catalyze ten reactions in turn.

Figure 7.6 Glycolysis Converts Glucose to Pyruvate

Figure 7.6 Glycolysis Converts Glucose to Pyruvate

ATP transfers a phosphateto the 6-carbon sugar glucose.

Figure 7.6 Glycolysis Converts Glucose to Pyruvate

Glucose 6-phosphateis rearranged to formits isomer, fructose6-phosphate.

Figure 7.6 Glycolysis Converts Glucose to Pyruvate

A second ATPtransfers a phosphateto create fructose1,6-bisphosphate.

The fructose ring opens,and the 6-carbon fructose1,6-bisphosphate breaksinto the 3-carbon sugarphosphate DAP and itsisomer G3P.

Figure 7.6 Glycolysis Converts Glucose to Pyruvate

The DAP moleculeis rearranged to formanother G3P molecule.

Figure 7.6 Glycolysis Converts Glucose to Pyruvate

The two moleculesof G3P gain phosphategroups and are oxidized,forming two moleculesof NADH + H+ and twomolecules of1,3-bisphosphoglycerate(BPG).

Figure 7.6 Glycolysis Converts Glucose to Pyruvate

The two molecules ofBPG transfer phosphategroups to ADP, formingtwo ATPs and two moleculesof 3-phosphoglycerate (3PG).

Figure 7.6 Glycolysis Converts Glucose to Pyruvate

The phosphate groupson the two 3PGs move,forming two 2-phospho-glycerates (2PG).

Figure 7.6 Glycolysis Converts Glucose to Pyruvate

The two molecules of2PG lose water, becomingtwo high-energy phospho-enolpyruvates (PEP).

Figure 7.6 Glycolysis Converts Glucose to Pyruvate

Finally, the two PEPstransfer their phosphatesto ADP, forming two ATPsand two molecules ofpyruvate.

Figure 7.6 Glycolysis Converts Glucose to Pyruvate

Figure 7.6 Glycolysis Converts Glucose to Pyruvate