Expert Forum

OPTIMAL TREATMENTOF CARDIOVASCULAR DISEASES:SURGERY VS. INNOVATIVE TECHNIQUES

Final Program

July 2&3, 2012

Nobile Collegium Universitas Aromatariorum Urbis Rome, Italy

Program Director Prof. Luigi Chiariello,Rome, Italy

http://www.iccsexpertforum.it

Over the past few years, more and more innovative and less invasive techniques have been introduced for treatment of cardiovascular diseases. Some of them have received an enthusiastic acceptance, not necessarily justified by clinical results. Simultaneously surgical techniques have been further refined, reaching surprisingly excellent results even in the very old population and in complex cases.

In the last decades of last century coronary angioplasty became widespread all over the world, generating the impression that bypass surgery may have shortly disappeared. However, the results of the latest Syntax Study have failed to demonstrate the “non-inferiority” of angioplasty vs. coronary bypass surgery in large numbers of patients.

Currently, the cardiovascular scene is dominated by the introduction in clinical practice of TAVI, mitral clip, aortic endoprostheses and hybrid procedures. There is no doubt that some of these costly procedures, or their evolutions, will find a place in the routine therapeutic armamentarium for at least some selected groups of patients. In most instances, however, not only their superiority, but even their “non-inferiority”over surgical alternatives still needs to be demonstrated.

The Italian College of Cardiac Surgeons intends to invite the cardiovascular community to the ongoing Expert Forum, as a way to bring into focus the best procedures for treatment of cardiovascular diseases.

The venue of the meeting will be inside the unique scenario of the Roman Imperial Forum. I hope you will enjoy your stay in a city rich in millennial vestigia as well as contemporary attractions.

I look forward to meeting you in Rome next July.

Welcome Address

Luigi Chiariello, President

Yours sincerely,

Luigi Chiariello, President

Yours sincerely,

Mon

day,

Jul

y 2

8:45 Welcome address: L. Chiariello

Address of President Italian College Cardiologists: M. Volpe

Address of President Italian College Radiologists: G. Biti

Session 1 Options in Valvular Heart Diseases

Aortic Valve President: M. Cotrufo Chairmen: M. Toscano, M. Volpe

9:00 The real surgical risk (“score”) of AVR in the elderly and in redo cases: G. Di Giammarco

9:15 Long term results of AVR: G. Gerosa

9:30 Early and late results of TAVI: Insights from Registry data: C. Tamburino

9:45 Sutureless aortic valves: Is there a need?: T. Fischlein

10:00 Discussion: M. Chello, O. Dapunt, P. Loschiavo, R. Violini

10:30 Coffee break

Mitral Valve President: Be. Marino Chairmen: F. Fedele, A. Pellegrino, A. Penta de Peppo

11:00 Early and late results of surgical mitral valve repair: F. Alamanni

11:15 Mitral clip: present results and realistic expectations: O. Alfieri

11:30 Transcatheter ablation for persistent atrial fibrillation: E. Bertaglia

11:45 Endoscopic surgical treatment for persistent atrial fibrillation: C. Muneretto

12:00 Discussion: M. Benomar, S. Grego, P. Polisca, A. Scafuri

12:30 Round-table: Socio-economical impact of innovative techniques

Chairman: R. Napoletano Panelists: F. Bevere, D. Bianchi, L. Chiariello, F. Conti, F. Romano, E. Sansavini

13:40 Lunch

Session 2 Options in Coronary Revascularization

President: F. Donatelli Chairmen: F. Alessandrini, A. Rebuzzi, F. Romeo

15:00 SYNTAX at 4 years: is CABG still the gold standard for multivessel disease?

For the motion: D.P. Taggart

Against the motion: D. Antoniucci15:30 SYNTAX at 4 years: is CABG still the gold standard for left main disease?

For the motion: D.P. Taggart

Against the motion: F. Tomai16:00 Sutureless aorto-safenous graft anastomosis: is there a need? : C. Bassano

16.10 Discussion : C. Briguori, E. Martuscelli, F. Pizzuto, M. Portoghese

16:30 Coffee break President: G. Condorelli Chairmen: A. Boccanelli, E. Covino

17:00 Transendocardial cell therapy in the failing heart: K. Jaquet

17:15 Discussion: E. Caradonna

17:20 Debate: There is no limit for recurrent PTCA and number of stents to be implanted

For the motion: A. Colombo, C. Indolfi

Against the motion: R.Mohr, M. Rinaldi

18:00 Closure

Tues

day,

Jul

y 3

Session 3 Options in Thoracic Aorta Lesions

President: T. Gherli Chairmen: A. Ippoliti, G. Nappi

9:00 Surgery of ascending aorta: early and late results: A. Mazzucco

9:15 Stenting of the thoracic aorta: is ascending aorta off-limits?: I. Loftus

9:30 “Fresh and Frozen” elephant trunk: benefits and pitfalls: M. Shrestha

9:45 Descending thoracic aorta: TEVAR results: E. Pampana

10:00 Complications and failure of TEVAR: new surgical challenge : R. Di Bartolomeo

10:15 Type B dissection: the right timing for TEVAR: R.Chiesa

10:30 Discussion: S. Corneo, A.M. D’Armini, R. Parravicini, R. Sinatra

11:00 Coffee break

Session 4 “We can work together: the hybrid procedures” President: P. Biglioli Chairmen: G. Biti, F. Crea, G. Simonetti

11.30 Hybrid coronary and carotid revascularization (The SHARP Study): F. Versaci

11:45 Hybrid coronary revascularization vs total CABG: M. Halkos

12:00 Aortic arch surgery: total surgical replacement vs hybrid approach: J. Zeitani

12:15 Hybrid repair of Mega Aortic Syndrome: the Lupiae Technique: G. Esposito

12:30 Discussion: R. De Paulis, M. Massetti, F. Miraldi, G. Passerone, G. Ruvolo

13:00 Chairpersons: E. Bollero, M.L. Garofalo

Debate: The Hybrid operating room should become a standard in highly specialized hospitals The Technician: E. Brusoni

The Surgeon: G.Polvani

13:30 Lunch

Session 5 Options in Congenital Heart Diseases

President: G. Pongiglione Chairmen: G. Gagliardi, G. Gargiulo Aortic valve stenosis

15:00 Transcatheter treatment of congenital aortic stenosis: O. Milanesi

15:15 Aortic valve surgery in children: the lesson learned over the years: V. Hraska

15:30 Discussion: A. Carotti, F.S. Iorio

Septal defects repair15:45 Transcatheter closure: A. Donti

16:00 Mininvasive evolution of surgical treatment: G. Stellin

16:15 Discussion : A. Amodeo, S. Giannico, A. Rapacciuolo

16:30 Coffee break Pulmonary valve regurgitation in adult congenital population

President: M. Chiavarelli Chairmen: A. Carotti, Br. Marino

17.00 Transcatheter pulmonary valve insertion in failing right ventricle: A. Rapacciuolo

17.15 Surgical RVOT remodelling: C. Vosa

17.30 Discussion: G. Gargiulo, V. Hraska, G. Pongiglione, G. Stellin

17.45 Closing Remarks: L. Chiariello

Program descriptionThe resulting scientific program represents a worldwide overview of the traditional surgical approach vs. innovative technical solutions for the treatment of cardiovascular diseases, such as hybrid approach or less-invasive percutaneous therapies. While surgery continues to be the gold standard therapy for most patients, subsets of patients may benefit from less-invasive innovative therapeutic solutions.

Educational objectives- To present the current state -of-the-art of cardiac surgery- To learn the options and patients selection for TAVI and Mitral-Clip procedures- To update CABG vs. PCI results in Left Main-Multivessel Coronary Artery Disease- To learn the options and perspectives for endovascular vs. open treatment of aortic aneurysms- To discuss the current state of hybrid procedures for aortic, coronary and peripheral artery diseases- To learn the options for percutaneous vs. open surgery for treatment of congenital heart diseases

- To learn the possible advantages of a dedicated hybrid operating room- To define expanding costs of innovative techniques and their socio-economical implications

Target AudienceThis forum is designed for cardiac surgeons, cardiologists, interventional radiologists, vascular surgeons, cardiovascular anaesthesiologists, perfusionists, health care managers.

Disclosure StatementIt is policy of the Italian College of Cardiac Surgeons to ensure balance, independence, objectivity and scientific rigor in its educational activities.Commercial support from industry does not influence educational content, faculty selection and/or faculty presentations and, therefore, does not compromise the scientific integrity of the educational activity.

Faculty members participating in this educational program are required to disclose to the audience any real or apparent conflicts of interest related to the content of their presentations.

Poster Submission Posters (140 cm x 100 cm) inherent to the forum topics are welcomed. Poster’s abstract should be sent to the Scientific Committee on-line at www.iccsexpertforum.itDeadline for abstracts submission is June 7, 2012, acceptance will be notified by June 9, 2012. Abstracts (max 250 words) and posters should be in English, the title printed in capital letters, the text divided in four sections (Objective, Methods, Results, Conclusions) The abstract should be sended to info@equa.it

Program Director

Luigi Chiariello, MDPhone: +39 06 20903536Fax: +39 06 20903538Mail: luigi.chiariello@uniroma2.it

How to register Register online at: www.iccsexpertforum.itFax this form to: +39 06 20903538 +39 06 32110090E-mail information above with the program title to: info@equa.it

Registration informationThere is no registration fee. Pre-registration is needed. Admission to the Forum will be limited to the first 180 requests.

Certificate of Attendance Attendance certificates will be released by the Organizing Secretariat at the end of Forum.

Official languages English and Italian – Slides and Posters must be in English.

Scientific Secretariat Paolo Nardi, MD Jacob Zeitani, MD

Organizing SecretariatEQUA srl Via del Babuino 79, 00187, RomeTel: +39 06 3236254 Fax: +39 06 32110090Website: www.equa.it E-mail: info@equa.it

Graphic design

Location The Forum will be held at the Nobile Collegium, Universitas Aromatariorum Urbis in Rome, located inside the Roman Imperial Forum Via in Miranda 10, 00186 Rome

Hotel Accomodation

Hotel Capo D’Africa**** hotelcapodafrica.comVia Capo d’Africa, 54 00184 Telefono 06 772801

Hotel Fourtyseven**** fortysevenhotel.com Via Luigi Petroselli, 47 00186 Telefono 06 678 7816

Delta Colosseo**** accorhotels.com Via Labicana, 144 00184 Telefono 06770021

Hotel Palatino**** hotelpalatino.comVia Cavour, 213 00184 Telefono 06 481 4927

Hotel Cosmopolita**** hotel-cosmopolita.comVia di Sant’Eufemia, 5 00187 Telefono 06 997071

Hotel Lancelot*** lancelothotel.comVia Capo D’Africa, 47Telefono 06 70450615

Faculty

Francesco Alamanni, MD Monzino Cardiologic Center, University of Milan, Milan - Italy

Francesco Alessandrini, MD Università Cattolica del Sacro Cuore, Campobasso - Italy

Ottavio Alfieri, MD San Raffaele Hospital, Vita-Salute University, Milan - Italy

Antonio Amodeo, MD Bambino Gesù Children’s Hospital, Rome - Italy David Antoniucci, MD Carreggi University Hospital, Florence - Italy Carlo Bassano, MD Policlinico Tor Vergata University, Rome - Italy M’Hamed Benomar, MD Centre Hospitalier Universitarie, Rabat - Maroc Emanuele Bertaglia, MD Mirano Civil Hospital, Venice - Italy

Francesco Bevere, Dr, General Manager Ministry of Health, Rome - Italy Davide Bianchi, President Heart Valve Unit, Sorin Group, Saluggia - Italy

Paolo Biglioli, MD University of Milan - Italy

Giampaolo Biti, MD University of Florence, Florence - Italy

Alessandro Boccanelli, MD S. Giovanni Addolorata Hospital, Rome - Italy

Enrico Bollero, MD,General Manager Policlinico Tor Vergata Foundation, Rome - Italy Carlo Briguori, MD Clinica Mediterranea, Naples - Italy

Enrico Brusoni, Engineer Siemens Healthcare Italia, Milan - Italy Eugenio Caradonna, MD Università Cattolica del Sacro Cuore, Campobasso - Italy

Adriano Carotti, MD Bambino Gesù Children’s Hospital, Rome - Italy

Massimo Chello, MD Campus Biomedico University, Rome - Italy

Luigi Chiariello, MD Policlinico Tor Vergata University, Rome - Italy Mario Chiavarelli, MD University of Siena - Italy

Roberto Chiesa, MD San Raffaele Hospital, Vita-Salute University, Milan - Italy Antonio Colombo, MD San Raffaele Hospital Scientific Institute, Milan - Italy

Gianluigi Condorelli, MD Milano-Bicocca University, Milan - Italy

Francesco Conti, Government Affaire Manager Medtronic Italia, Milan - Italy Stefano Corneo, Engineer Bolton Medical Srl, Milan - Italy

Maurizio Cotrufo, MD 2nd University of Naples, Naples - Italy

Elvio Covino, MD Campus Biomedico University, Rome - Italy

Filippo Crea, MD Università Cattolica del Sacro Cuore, Rome - Italy Otto Dapunt, MD Cardiothoracic Surgery, Klinikum Oldenburg - Germany

Andrea M. D’Armini, MD University Hospital San Matteo, Pavia - Italy Ruggero De Paulis, MD Casa di Cura European Hospital, Rome - Italy

Roberto Di Bartolomeo, MD Policlinico S. Orsola Malpighi University of Bologna - Italy

Gabriele Di Giammarco, MD Chieti University, SS. Annunziata Hospital, Chieti - Italy

Francesco Donatelli, MD University of Milan IRCCS MultiMedica Sesto S.Giovanni, Milan - Italy

Andrea Donti, MD Policlinico S. Orsola Malpighi University of Bologna - Italy

Giampiero Esposito, MD Humanitas Gavazzeni Clinic Institute - Italy Francesco Fedele, MD Sapienza University, Policlinico Umberto I, Rome - Italy

Theodor Fishlein, MD Klinikum Nürnberg, Nuremberg - Germany Giulia Gagliardi, MD Bambino Gesù Children’s Hospital, Rome - Italy Gaetano Gargiulo, MD Policlinico S. Orsola - Malpighi University of Bologna - Italy

Maria Laura Garofalo, Dr, Managing Director Gruppo Garofalo, Rome - Italy

Gino Gerosa, MD Padua University Hospital, Padua - Italy

Tiziano Gherli, MD Parma University Hospital, Parma - Italy Salvatore Giannico, MD Bambino Gesù Childrens’ Hospital, Rome - Italy Susanna Grego, MD Policlinico Tor Vergata University, Rome - Italy Michael Halkos, MD Emory University, Atlanta, Georgia, USA

Viktor Hraska, MD University Hospital Eppendorf-Hamburg, Hamburg - Germany

Ciro Indolfi, MD Magna Graecia University, Catanzaro - Italy

Fiore S. Iorio, MD Tor Vergata University of Rome - Italy, Jedda - Saudi Arabia

Arnaldo Ippoliti, MD Policlinico Tor Vergata University, Rome - Italy Kay Jaquet, MD Asklepios Klinik St. Georg, Hamburg - Germany Ian Loftus, MD St. George’s Vascular Institute, London - UK

Paolo Loschiavo, MD Sandro Pertini Hospital, Rome - Italy Benedetto Marino, MD Sapienza University, Rome - Italy Bruno Marino, MD Sapienza University, Policlinico Umberto I, Rome - Italy Eugenio Martuscelli, MD Policlinico Tor Vergata University, Rome – Italy Massimo Massetti, MD Università Cattolica del Sacro Cuore, Rome - Italy Alessandro Mazzucco, MD University Hospital of Verona, Verona - Italy Fabio Miraldi, MD Sapienza University, Policlinico Umberto I, Rome - Italy Ornella Milanesi, MD Padua University Hospital, Padua - Italy

Raphael Mohr, MD Sourasky Medical Center, Tel Aviv - Israel Claudio Muneretto, MD University of Brescia P.le Spedali Civili, Brescia - Italy

Roberto Napoletano, Dr, Director Il Sole 24 Ore - Italy

Giannantonio Nappi, MD Monaldi University Hospital, Naples - Italy Enrico Pampana, MD Policlinico Tor Vergata University, Rome - Italy

Roberto Parravicini, MD Policlinico di Modena, University of Modena, Modena - Italy

Giancarlo Passerone, MD San Martino Hospital, University of Genoa, Genoa - Italy Antonio Pellegrino, MD Policlinico Tor Vergata University, Rome - Italy Alfonso Penta de Peppo, MD 2nd University of Naples, Naples - Italy

Francesco Pizzuto, MD Policlinico Tor Vergata University, Rome - Italy

Patrizio Polisca, MD Policlinico Tor Vergata University, Rome - Italy

Gianluca Polvani, MD Monzino Cardiologic Center, University of Milan, Milan - Italy

Giacomo Pongiglione, MD Bambino Gesù Children’s Hospital, Rome - Italy

Michele Portoghese, MD Sassari Hospital, Sassari - Italy Antonio Rapacciuolo, MD Policlinico Federico II, University of Naples, Naples - Italy Antonio Rebuzzi, MD Università Cattolica del Sacro Cuore, Rome - Italy

Mauro Rinaldi, MD Molinette University Hospital, Turin - Italy

Ferdinando Romano, MD, Public Administrator Regione Lazio, Rome - Italy

Francesco Romeo, MD Policlinico Tor Vergata University, Rome - Italy

Giovanni Ruvolo, MD Paolo Giaccone University Hospital, Palermo - Italy Ettore Sansavini, General Manager Villa Maria Private Hospitals - Italy

Antonio Scafuri, MD Policlinico Tor Vergata University, Rome - Italy

Malakh Shrestha, MD Hannover Medical School, Hannover - Germay Giovanni Simonetti, MD Policlinico Tor Vergata University, Rome - Italy

Riccardo Sinatra, MD Sapienza University, Sant’Andrea Hospital, Rome - Italy Giovanni Stellin, MD Padua University Hospital, Padua - Italy

David P. Taggart, MD John Radcliffe Hospital, Oxford - UK

Corrado Tamburino, MD University of Catania – Italy

Fabrizio Tomai, MD Casa di Cura European Hospital, Rome - Italy Michele Toscano, MD Sapienza University, Policlinico Umberto I, Rome - Italy

Francesco Versaci, MD Campobasso & Isernia Hospitals – Italy

Roberto Violini, MD San Camillo Hospital, Rome - Italy

Massimo Volpe, MD Sapienza University, Sant’Andrea Hospital, Rome - Italy Carlo Vosa, MD Policlinico Federico II, University of Naples, Naples - Italy

Jacob Zeitani, MD Policlinico Tor Vergata University, Rome - Italy

Gold

Silver

Bronze

Under the Kind Patronage of

Many thanks for their contribute to the scientific event also to: Baxter, Cremascoli & Iris, Edwards THV, Elitrade, Gada Italia, Omniamed, Serom Medical Technology, St. Jude Medical.

Sponsors