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28.1 Levels of Organization
Five Levels of Organization
Cell Tissue Organ Organ System Organism
ORGANS
ORGAN SYSTEM
ORGANISM
35.1 Human Body Systems
28.1 Levels of Organization
KEY CONCEPT Homeostasis is the regulation and maintenance of the internal environment.
35.1 Human Body Systems
28.1 Levels of Organization
pore
sweat glands
hairfolliclemuscle
goosebump
Conditions within the body must remain within a narrow range.• Homeostasis involves keeping the internal environment
within set ranges that support lifeex: temperature, fluids, salt, pH
• Control systems help maintain homeostasis. – sensors gather data– control center receives
data, sends messages – communication system
delivers messages to target organs, tissues
– targets respond to change
35.1 Human Body Systems
28.1 Levels of Organization
Homeostasis is maintained by feedback loops. • Feedback compares current conditions to set ranges.• Two types of feedback loops:
1) Negative feedback= counteracts change; more commonex: temperature & O2/CO2 regulation (↓)
Negative Feedback Loop
Holding breath, CO2 levels rise,
Control system forces exhale, inhale
O2 / CO2 level returns to normal
35.1 Human Body Systems
28.1 Levels of Organization
2) Positive feedback = increases change; less commonex - During childbirth, oxytocin enhances (↑) labor
contraction - Torn vessel stimulates (↑) release of clotting factors- Growth hormones stimulate (↑) cell division
platelets
fibrin
white blood cellred blood cell
blood vessel
clot
35.1 Human Body Systems
29.2 Neurons
KEY CONCEPT The nervous system controls and coordinates functions throughout the body and responds to internal and external stimuli.
35.2 The Nervous System
29.2 Neurons
• A stimulus causes a response.ex: When you touch something hot (stimulus), you
immediately pull your hand away (response).• Messages carried by the nervous system are called
impulses.
35.2 The Nervous System
29.2 Neurons
1) electrical impulse = due to the differences in electricalcharges across the nerve cell membrane;aka “action potential”
35.2 The Nervous System
29.2 Neurons
2) chemical impulse = due to the move movement ofchemical messengers between nerve cells
29.2 Neurons
The nervous system is composed of highly specialized cells called neurons.• A neuron has three parts.
– cell body has nucleus and organelles
1 Cell body
35.2 The Nervous System
29.2 Neurons
– dendrites receive impulses
Neurons are highly specialized cells.
• A neuron has three parts.– cell body has nucleus and organelles
2 dendrites
35.2 The Nervous System
29.2 Neurons
– axon sends impulse to next cell through the axon terminal
3 axon
– dendrites receive impulses
Neurons are highly specialized cells.
• A neuron has three parts.– cell body has nucleus and organelles
axon terminal
35.2 The Nervous System
29.2 Neurons
• The axon is wrapped in a myelin sheath
– Made up of Schwann cellsinsulated impulse cannot go through
– Gaps between are the nodes of Ranviernot insulated impulse can go through
Schwann cell Nodes of Ranvier
35.2 The Nervous System
29.2 Neurons
signal
direction
• The axon is wrapped in a myelin sheath– Myelin sheath speeds up the impulse – Impulse “jumps” from one node of Ranvier to the next– 330 mph (myelinated) vs. 11 mph (unmyelinated)
35.2 The Nervous System
29.2 Neurons
17
Types of neurons1.sensory neuron
(from senses)
2. interneuron(brain & spinal chord)
3. motor neuron(to muscle)
35.2 The Nervous System
29.2 Neurons
Synaptic Transmission• Neurotransmitters
- chemical messengers that transmit impulse between nerve cells
- contained in small vesicles in axon terminal• Synapse
- junction between two nerve cells
35.2 The Nervous System
29.2 Neurons
Synaptic Transmission1) Impulse reaches axon terminal and vesicles fuse to
presynaptic membrane – release chemicals into synapse (exocytosis)
2) Neurotransmitters diffuse across the synapse (diffusion)3) Neurotransmitters bind to
receptors in postsynaptic membrane
4) Neurotransmitters are taken back up into vesicles (endocytosis)or destroyed by enzymes
35.2 The Nervous System
29.4 Central and Peripheral Nervous Systems
KEY CONCEPT The central nervous system interprets information, and the peripheral nervous system gathers and transmits information.
35.3 Divisions of the Nervous System
29.4 Central and Peripheral Nervous Systems
The nervous system’s two parts work together.
• The CNS includes - brain- spinal cord
• The PNS includes – sensory receptors– 12 cranial nerves– 31 spinal nerves– connects CNS
to rest of the body
35.3 Divisions of the Nervous System
29.4 Central and Peripheral Nervous Systems
The PNS links the CNS to muscles and other organs.• The somatic nervous system regulates voluntary
movements.• The autonomic nervous system
controls involuntary, functions
– sympathetic nervous system: “fight vs. flight”
– parasympathetic nervous system: calms the body, conserves energy
35.3 Divisions of the Nervous System
29.4 Central and Peripheral Nervous Systems
• The CNS and PNS pass signals between one another.– Sensory receptor (PNS) generates impulse. – PNS passes impulse to CNS through the sensory
neurons– Interneurons in CNS interpret impulse and make a
decision.– CNS passes the decision (impulse) to the motor neurons
of the PNS. – Motor neurons (PNS) stimulate a response by a muscle
or gland (effectors).
35.3 Divisions of the Nervous System
29.4 Central and Peripheral Nervous Systems
The CNS processes information.
• The brain has three parts. – cerebrum controls
thought, memory, movement, emotion
– cerebellum allows for balance
midbrainpons
medulla oblongata
– brain stem controls basic life functions
Brainstem
35.3 Divisions of the Nervous System
29.4 Central and Peripheral Nervous Systems
Cerebrum• Largest part of brain• Made up of right and left hemispheres connected by
corpus callosum
35.3 Divisions of the Nervous System
29.4 Central and Peripheral Nervous Systems
Cerebrum• Cerebral cortex
– gray matter– highly folded outer layer of cerebrum
• Below the cerebral cortex - white matter - connects cortex to other parts of nervous system
35.3 Divisions of the Nervous System
29.4 Central and Peripheral Nervous Systems
Cerebrum• Right hemisphere
- controls verbal and nonverbal artistic abilities
- “creative side”• Left hemisphere
- controls reading, writing, and analyzing
- “logic side”
35.3 Divisions of the Nervous System
29.4 Central and Peripheral Nervous Systems
• The brain stem has three parts.– midbrain controls some
reflexes– pons regulates breathing
and is the relay station between cerebrum and cerebellum
– medulla oblongata controls heart function, swallowing, coughing
midbrain
medulla oblongata
pons
35.3 Divisions of the Nervous System
29.4 Central and Peripheral Nervous Systems
• The spinal cord controls reflexes. – sensory neuron sends impulse to interneuron in spinal
cord– spinal cord directs impulse to motor neuron – does not involve the brain
interneuron
motor neurons
sensory neuron
35.3 Divisions of the Nervous System
29.3 The Senses
KEY CONCEPT The senses detect the internal and external environments.
35.4 The Senses
29.3 The Senses
The senses help to maintain homeostasis.
• Senses gather stimuli, and send it to the nervous system.
• Nervous system responds to stimuli.– Pupils shrink when too much
light enters the eyes.– Goose bumps when cold air
touches skin.
35.4 The Senses
29.3 The Senses
The senses detect physical and chemical stimuli.
• The eye contributes to vision. – Photoreceptors sense light.– Two photoreceptors work
together: rod cells and cone cells.
35.4 The Senses
29.3 The Senses
• The ear contributes to hearing.
– mechanoreceptors called hair cells – bend in response to vibrations
35.4 The Senses
29.3 The Senses
• Taste and smell use chemoreceptors.
– Taste uses tongue, and smell uses nose.– Chemoreceptors detect chemicals dissolved in fluid.
35.4 The Senses
29.3 The Senses
• The skin senses touch.
– Mechanoreceptors detect pressure.
pain receptor
light pressure receptor
hair follicle
heavy pressure receptor
– Pain receptors detect damaged tissue.– Thermoreceptors detect temperature.
35.4 The Senses
http://www.bbc.co.uk/science/humanbody/body/interactives/3djigsaw_02/index.shtml?nervous
29.6 The Endocrine System and Hormones
KEY CONCEPT The endocrine system produces hormones that affect growth, development, and homeostasis.
39.1 The Endocrine System
29.6 The Endocrine System and Hormones
How does endocrine system work?• Works closely with nervous system• Nervous system detects changes
Endocrine gland
sends signal to
Hormonetravels through bloodstream to
Target cell
secretes
Restores homeostasis
39.1 The Endocrine System
29.6 The Endocrine System and Hormones
• Endocrine glands are organs of the endocrine system• Hormones are chemical signals that influence cell’s
activities.– produced by glands– travel through the circulatory system– affects target cells with matching receptors
target cell
hormone
receptornot a target cell
bloodstream
39.1 The Endocrine System
29.6 The Endocrine System and Hormones
Endocrine glands secrete hormones that act throughout the body.
• There are many glands located throughout the body.
HYPOTHALAMUS
PITUITARY
THYROID
THYMUS
ADRENAL GLANDSPANCREASFEMALE GONADS :OVARIES
MALE GONADS : TESTES
39.1 The Endocrine System
29.6 The Endocrine System and Hormones
Types of Endocrine glandsControls pituitary and other glands – connects Nervous sys and Endocrine sys
Makes hormones that control other glands
Makes thyroxin to control metabolism
Makes thymosin to help white blood cells to mature
Make adrenaline to prepare body for emergencies
Makes insulin and glucagon to control blood glucose levels
Controls secondary sex characteristics
Makes testosterone in men and estrogen and progesterone in women
39.1 The Endocrine System
29.6 The Endocrine System and Hormones
Negative Feedback of Blood Glucose• Blood Glucose Level (BGL) is regulated by
1) insulin = ↓ BGL2) glucagon = ↑ BGL
• Both hormones are secreted by the pancreas
liverpancreas
liver
blood sugar level(90mg/100ml)
insulin
body cells takeup sugar
from blood
liver storessugar
reducesappetite
glucagonpancreas
liver releases
sugar
triggershunger
high
low
39.1 The Endocrine System
29.6 The Endocrine System and Hormones
Negative Feedback of Blood GlucoseAfter Meal
Pancreas releases insulin
Insulin pushes glucose into the target cells
Restores homeostasis
BGL ↑
BGL ↓
After Exercise
Pancreas releases glucagon
Glucagon binds to liver
Restores homeostasis
BGL ↑
BGL ↓
Liver releases glucose
39.1 The Endocrine System