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1www.medixbiochemica.com
FOR EXCELLENCE IN DIAGNOSTICS– We’re bound to deliver
ANTIBODIESMedixMAB™
FAB-FRAGMENTSMedixMAB™
ANTIGENSMedix
™
2
CARDIOVASCULAR MARKERS .......................................................4Cardiac troponin I (cTnI) Cardiac troponin T (cTnT)Copeptin Creatine kinase (CK-MB)D-dimerFatty-acid-binding protein 3 (FABP3)Galectin-3Myeloperoxidase (MPO)MyoglobinN-terminal prohormone & prohormone of natriuretic peptide (NT-proBNP & proBNP)S100BST2
DIABETES & METABOLISM ...........................................................8AdiponectinAlbuminApolipoprotein A1 (ApoA1)Apolipoprotein B (ApoB)C-peptideFerritinGlycated hemoglobin (HbA1c)LactoferrinTransferrin
HORMONES ..............................................................................10Alpha subunitChorionic gonadotropin (HCG)Follicle-stimulating hormone (FSH)Growth hormone (GH)Luteinizing hormone (LH)Progesterone (PR)Prolactin (PRL)Sex hormone-binding globulin (SHBG)
INFECTIOUS DISEASES................................................................12Bocavirus (hBoV)Chlamydia trachomatisCoronavirusHepatitis B virus (HBsAg)Influenza A
FOR EXCELLENCE IN DIAGNOSTICS– We’re bound to deliver
3
Influenza BPlasmodium falciparum HRP2Respiratory syncytial virus (RSV)
INFLAMMATION ........................................................................14Alpha 1-antitrypsin (AAT)C-reactive protein (CRP)CalprotectinInterleukin-6 (IL-6)Interleukin-8 (IL-8)LactoferrinProcalcitonin (PCT)Serum amyloid A (SAA)TransferrinTrypsinogen-2
KIDNEY MARKERS .....................................................................17Cystatin C Neutrophil gelatinase-associated lipocalin (NGAL)
SEROLOGY ................................................................................18Immunoglobulin A (IgA)Immunoglobulin E (IgE)Immunoglobulin G (IgG)Immunoglobulin M (IgM)
THYROID ..................................................................................19ThyroglobulinThyroid-stimulating hormone (TSH)Thyroxine (T4)
TUMOR MARKERS .....................................................................20Alpha-fetoprotein (AFP)Cancer antigen 15-3 (CA15-3)Cancer antigen 125 (CA125)Carbohydrate antigen 19-9 (CA19-9)Carcinoembryonic antigen (CEA)CYFRA21-1Hemoglobin (Hb)Human epididymis protein 4 (HE4) Neuron-specific enolase (NSE)Pepsinogen (PG I & II)Prostate-specific antigen (PSA)
All product specifications can be found online: www.medixbiochemica.com
* Concentration: mg/ml (+/- 10%)4
CARDIOVASCULARMARKERS PRODUCT CONC.* REF.
Cardiac troponin I (cTnI)
Troponins form a complex (Troponin C, I and T) and are involved in muscle contraction. Troponin levels can be used as a test for several different heart disorders, including myocardial infarction.
MONOCLONAL ANTIBODIES
MAB 9701 5 100129MAB 9703 5 100181MAB 9705 1 100125MAB 9707 5 100180MAB 9708 5 100523MAB 9709 5 100524
FAB-FRAGMENTFAB 9707 600000
RECOMBINANT ANTIGENcTnI antigen 610102 NEW
Cardiac troponin T (cTnT)
Troponins form a complex of three regulatory proteins (troponin C, I and T) that are integral to muscle contraction in skeletal and cardiac muscles. Serum cardiac troponin tests can be used to help diagnose several different heart disorders, especially myocardial infarction.
MONOCLONAL ANTIBODIESMAB 37XX TBD TBD
RECOMBINANT ANTIGENcTnT antigen 610101 NEW
Copeptin
is a 39-amino acid glycopeptide, cleaved from the C-terminus of pre-provasopressin (pre-proAVP). It has been suggested as a biomarker in diagnosis and prognosis of several diseases, such as acute myocardial infarction, heart failure, hyponatremia, and sepsis.
MONOCLONAL ANTIBODIESMAB 4801 TBD TBDMAB 4802 TBD TBDMAB 4804 TBD TBDMAB 4806 TBD TBD
Creatine kinase (CK-MB)
is a dimeric enzyme consisting of two subunits, which can be either B (brain type) or M (muscle type). CK-MB is used for diagnosis of myocardial infarction.
MONOCLONAL ANTIBODIESMAB 7501 5 100630MAB 7502 5 100086
UPCOMING
UPCOMINGUPCOMINGUPCOMINGUPCOMING
All product specifications can be found online: www.medixbiochemica.com 5
CARDIOVASCULARMARKERS PRODUCT CONC.* REF.
D-dimer
is a small degradation product of cross-linked fibrin. D-dimer is released in the blood during fibrinolysis and it is used to diagnose pulmonary embolism and deep vein thrombosis.
MONOCLONAL ANTIBODIESMAB 1401 5 100204MAB 1402 5 100205MAB 1403 5 100228MAB 1404 5 100479MAB 1405 5 100480MAB 1406 5 100481MAB 1407 5 100482
Fatty-acid-binding protein 3 (FABP3)
is a family of carrier proteins for fatty acids and other lipophilic substances. Heart-FABP (FABP3) can be used as a diagnostic marker in the early phase of acute myocardial infarction.
MONOCLONAL ANTIBODIESMAB 2302 5 100292MAB 2303 5 100293MAB 2304 5 100294
RECOMBINANT ANTIGENFABP3 antigen 610043
Galectin-3
is a beta-galactosidase- binding lectin. The expression of galectin-3 is upregulated during inflammation. It is used in assessing the prognosis of patients diagnosed with chronic heart failure. Galectin-3 is also involved in pathological processes including cancer, fibrosis and chronic inflammation.
RECOMBINANT ANTIGENGalectin-3 antigen TBD
Myeloperoxidase (MPO)
is an enzymatic mediator of inflammatory cascades and microbial killing. Higher serum levels of MPO have been associated with cardiovascular diseases.
MONOCLONAL ANTIBODIESMAB 1701 5 100266MAB 1702 5 100267MAB 1703 5 100268
Ca
rdio
va
scula
rm
ark
ers
UPCOMING
* Concentration: mg/ml (+/- 10%)6
CARDIOVASCULARMARKERS PRODUCT CONC.* REF.
Myoglobin
is an intracellular protein transporting oxygen in the cardiac and skeletal muscle cells. Myoglobin is one of the earliest biomarkers of cardiac injury.
MONOCLONAL ANTIBODIESMAB 7001 5 100378MAB 7004 5 100354MAB 7005 5 100078
RECOMBINANT ANTIGENMyoglobin antigen 610030
N-terminal prohormone and prohormone of natriuretic peptide (NT-proBNP & proBNP)
The plasma concentrations of both the N-terminal fragment of Pro-B-type natriuretic peptide (NT-ProBNP) and prohormone of brain natriuretic peptide (proBNP) are significantly increased in patients with asymptomatic and symptomatic left ventricular dysfunction.
MONOCLONAL ANTIBODYMAB NT-proBNP 1306 5 100521
FAB-FRAGMENTFAB NT-proBNP 1306 600025
RECOMBINANT ANTIGENNT-proBNP antigen 610090proBNP antigen 710017 NEW
S100B
belongs to the family of dimeric calcium-binding S100 proteins. S100B is a biomarker for traumatic brain injury.
RECOMBINANT ANTIGENS100B antigen 710014 NEW
ST2
is a member of interleukin-1 receptor family. ST2 protein has two isoforms: a soluble (sST2) and membrane- bound form. Patients with heart failure and elevated sST2 protein levels in the blood are at risk for heart failure progression.
RECOMBINANT ANTIGENST2 antigen 710020 NEW
All product specifications can be found online: www.medixbiochemica.com 7
Ca
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MEDIX BIOCHEMICA OFFERS EXCELLENT QUALITY
• In vitro production: uniform product quality with every batch.
• Serum and protein free culture media: no contaminating proteins.
• Large production capability: from milligrams to kilograms.
WHEN YOU WANT THE BEST,MEDIX BIOCHEMICA OFFERS
• Fast and reliable deliveries.
• Flexible customer service and expert technical support.
• Customer-focused research and development.
* Concentration: mg/ml (+/- 10%)8
DIABETES & METABOLISM PRODUCT CONC.* REF.
Adiponectin
is a protein hormone that modulates a number of metabolic processes that may lead to type 2 diabetes, obesity, atherosclerosis, and non-alcoholic fatty liver disease.
MONOCLONAL ANTIBODIESMAB 1901 5 100255MAB 1902 5 100256MAB 1903 5 100257
RECOMBINANT ANTIGENAdiponectin antigen 710013 NEW
Albumin
normally constitutes about 60% of human plasma proteins and is produced in the liver. It is important in regulating blood volume, and also serves as carriers for molecules in blood.
MONOCLONAL ANTIBODIESMAB 6501 1 100063MAB 6502 2 100064
Apolipoprotein A1 (ApoA1)
is a major component of the high-density lipoproteins (HDL) complex. ApoA1 helps clear cholesterol from arteries. ApoA1 has been suggested as a better discrimination of coronary artery disease than HDL.
MONOCLONAL ANTIBODIESMAB 2001 5 100263MAB 2002 5 100264
RECOMBINANT ANTIGENApoA1 antigen 710012 NEW
Apolipoprotein B (ApoB)
is the primary apolipoprotein of low-density lipoproteins (LDL), which is responsible for carrying cholesterol to tissues. High levels of ApoB can lead to plaques that cause atherosclerosis.
MONOCLONAL ANTIBODYMAB 2101 5 100261
C-peptide
is produced when proinsulin is split into insulin and C-peptide. C-peptide can be used to help determine how much insulin the patient’s pancreas is still producing.
MONOCLONAL ANTIBODIESMAB 9101 5 100113MAB 9103 5 100114
All product specifications can be found online: www.medixbiochemica.com 9
DIABETES & METABOLISM PRODUCT CONC.* REF.
Ferritin
binds and stores iron. It releases iron in controlled fashion normally preventing iron deficiency and iron overload in humans. The amount of ferritin in the serum is measured in relation to some chronic diseases and anemia.
MONOCLONAL ANTIBODIESMAB 8803 5 100111MAB 8806 5 100112
Glycated hemoglobin (HbA1c)
is measured primarily to identify the average plasma glucose concentration over prolonged periods of time. Higher levels are found in people with persistently elevated blood sugar, as in diabetes.
MONOCLONAL ANTIBODYMAB 2403 5 100301
Lactoferrin
Lactoferrin is an antimicrobial protein, also known as lactotransferrin, which transfers iron to the cells. It is used in a faecal test to detect inflammation in the intestine. Lactoferrin levels are associated with disease severity in intestinal bowel disease (IBD).
RECOMBINANT ANTIGENLactoferrin antigen 710016 NEW
Transferrin
regulates the amount of free iron in circulation. Transferrin concentration elevates in anemia, but can be also be used to diagnose other clinical conditions.
MONOCLONAL ANTIBODIESMAB 3104 5 100525MAB 3105 5 100440MAB 3106 5 100474
Dia
be
tes &
M
eta
bo
lism
* Concentration: mg/ml (+/- 10%)10
HORMONES PRODUCT CONC.* REF.
Alpha subunit
of LH, FSH, TSH, and HCG is identical. The biological activity of these hormones is evoked by the specific beta subunit.
MONOCLONAL ANTIBODIESMAB 5501 1 100035MAB 5503 1 100037MAB 6601 5 100066
Chorionic gonadotropin (HCG)
is a glycoprotein hormone produced in pregnancy and commonly utilized for early pregnancy testing. Testing for HCG may also be done when diagnosing or monitoring some tumors.
MONOCLONAL ANTIBODIESHCG beta:MAB 5004 5 100004MAB 5006 5 100005MAB 5008 5 100006MAB 5011 1 100009MAB 5014 5 100011MAB 5016 5 100013
HCG complex:MAB 5009 5 100008
HCG free beta:MAB 5012 5 100368
Follicle-stimulating hormone (FSH)
regulates the development, growth, pubertal maturation, and reproductive processes of the body. It is used to diagnose problems in the reproductive system.
MONOCLONAL ANTIBODYMAB 6602 5 100067
Growth hormone (GH)
is a single-chain polypeptide hormone. Growth hormone is used clinically to diagnose and treat children’s growth disorders and adult growth hormone deficiency.
MONOCLONAL ANTIBODIESMAB 5801 1 100041MAB 5802 1 100042
All product specifications can be found online: www.medixbiochemica.com 11
HORMONES PRODUCT CONC.* REF.
Luteinizing hormone (LH)
is essential for reproduction in both sexes. LH is measured to detect abnormalities in sexual development and reproductive functions.
MONOCLONAL ANTIBODIESMAB 5301 5 100016MAB 5302 1 100018MAB 5303 1 100019MAB 5304 5 100022
Progesterone (PR)
is a steroid hormone needed for normal reproduction. Progesterone levels are monitored during pregnancy and for an indication of ovarian cancer.
MONOCLONAL ANTIBODIESMAB 1801 5 100248MAB 1802 5 100249MAB 1803 5 100250MAB 1805 5 100252
Prolactin (PRL)
is a peptide hormone primarily associated with lactation. Prolactin is usually measured when checking for pituitary tumors or the cause of abnormal milk production.
MONOCLONAL ANTIBODIESMAB 5601 1 100038MAB 5602 5 100360
Sex hormone-binding globulin (SHBG)
binds to sex hormones, specifically testosterone and estradiol. Abnormally low or high SHBG levels are used to diagnose several non-physiological conditions.
MONOCLONAL ANTIBODIESMAB 6001 5 100539MAB 6002 5 100540MAB 6007 5 100569
Ho
rmo
ne
s
* Concentration: mg/ml (+/- 10%)12
INFECTIOUS DISEASES PRODUCT CONC.* REF.
Bocavirus (hBoV)
is a member of the Parvoviridae virus family. It is a newly described human pathogen that has been associated especially with lower respiratory tract and gastrointestinal infections, predominantly in children.
MONOCLONAL ANTIBODIESMAB 3601 5 100526MAB 3602 5 100527
Chlamydia trachomatis
is an intracellular pathogen and can cause numerous disease states in both men and women, such as urethritis, proctitis, trachoma, and infertility.
MONOCLONAL ANTIBODIESMAB 6701 5 100141MAB 6703 5 100071MAB 6709 5 100073
Coronavirus
is believed to cause a significant percentage of all common colds in human adults. Coronaviruses primarily infect the upper respiratory and gastrointestinal tract.
MONOCLONAL ANTIBODIESHCoV 229E: MAB 3501 5 100528MAB 3502 5 100529
HCoV OC43:MAB 3503 5 100530MAB 3504 5 100531MAB 3505 5 100532MAB 3506 5 100533
RECOMBINANT ANTIGENSHCoV OC43 N 610040HCoV NL63 N 610041HCoV HKU1 N 610042HCoV 229E N 610091 NEW
Hepatitis B virus (HBsAg)
causes liver inflammation, and chronic hepatitis B may eventually cause liver cirrhosis and liver cancer. The first detectable viral antigen to appear during infection is hepatitis B surface antigen (HBsAg).
MONOCLONAL ANTIBODIESMAB 2503 5 100351MAB 2505 5 100352MAB 2507 5 100502MAB 2508 5 100504MAB 2510 5 100568
All product specifications can be found online: www.medixbiochemica.com 13
INFECTIOUS DISEASES PRODUCT CONC.* REF.
Influenza A
is the most common cause of influenza, flu pandemics and most epidemics. Influenza A virus causes influenza in birds and some mammals.
MONOCLONAL ANTIBODIESMAB 7304 5 100081MAB 7305 5 100082MAB 7307 5 100083MAB 7314 5 100431
Influenza B
causes also seasonal epidemics but it is only known to infect humans and seals. This limited host range is apparently responsible for the lack of Influenza B caused pandemics.
MONOCLONAL ANTIBODIESMAB 9901 5 100117MAB 9905 5 100472MAB 9906 5 100437MAB 9908 5 100498MAB 9909 5 100473
Plasmodium falciparum HRP2 (Malaria)
is a histidine-rich protein secreted by the P. falciparum parasite. HRP2 detection is widely used in the diagnosis of malaria.
MONOCLONAL ANTIBODIESMAB 3901 5 100559MAB 3902 5 100560
RECOMBINANT ANTIGENHRP2 antigen 610081
Respiratory syncytial virus (RSV)
causes respiratory tract infections. It is the major cause of lower respiratory tract infection and hospital visits during infancy and childhood.
MONOCLONAL ANTIBODIESMAB 1201 10 100198MAB 1203 5 100200
Infe
ctiou
s D
isea
ses
* Concentration: mg/ml (+/- 10%)14
INFLAMMATION PRODUCT CONC.* REF.
Alpha 1-antitrypsin (AAT)
is a glycoprotein that protect the lungs from destructive actions of blood enzymes, generally known as serum trypsin inhibitor. Disorders of this protein include AAT-deficiency, a hereditary disorder leading to a chronic uninhibited tissue breakdown.
MONOCLONAL ANTIBODIESMAB 1002 5 100209MAB 1003 5 100210
C-reactive protein (CRP)
is a protein found in the blood and the levels rise in response to inflammation. CRP values are useful in determining disease progress or the effectiveness of treatments.
MONOCLONAL ANTIBODIESMAB 6402 5 100145MAB 6403 5 100146MAB 6404 2 100058MAB 6404 6 100061MAB 6405 5 100358MAB 6407 5 100147
FAB-FRAGMENTFAB 6404 600024
Calprotectin
belongs to the family of S100 proteins and is composed of two subunits S100A8 and S100A9. Increased concentrations are found in response to infections and inflammation.
MONOCLONAL ANTIBODIESS100A9:MAB 3401 5 100458MAB 3403 5 100460
S100A8:MAB 3404 5 100468MAB 3405 5 100469MAB 3406 5 100470
S100A8/S100A9 complex:MAB 3407 5 100618 NEW
RECOMBINANT ANTIGENS100A8/S100A9 antigen 610061 NEWS100A8 antigen 710018 NEWS100A9 antigen 710019 NEW
All product specifications can be found online: www.medixbiochemica.com 15
INFLAMMATION PRODUCT CONC.* REF.
Interleukin-6 (IL-6)
acts as both pro-inflammatory and anti-inflammatory cytokine. IL-6 is relevant to many disease processes such as diabetes, atherosclerosis, depression, Alzheimer’s Disease, cancer, and rheumatoid arthritis.
MONOCLONAL ANTIBODIESMAB 2703 5 100328MAB 2704 5 100329MAB 2706 5 100330
RECOMBINANT ANTIGENIL-6 antigen 710015 NEW
Interleukin-8 (IL-8)
is a chemokine which serves as a chemical signal that attracts neutrophils at the site of inflammation. IL-8 is a promising marker for many clinical conditions with inflammations.
MONOCLONAL ANTIBODYMAB 1501 5 100218
Lactoferrin
Lactoferrin is an antimicrobial protein, also known as lactotransferrin, which transfers iron to the cells. It is used in a faecal test to detect inflammation in the intestine. Lactoferrin levels are associated with disease severity in intestinal bowel disease (IBD).
RECOMBINANT ANTIGENLactoferrin antigen 710016 NEW
Procalcitonin (PCT)
is a precursor protein of the hormone calcitonin, associated with systemic infections. In clinical diagnostics, PCT test is most often used to identify patients with sepsis.
MONOCLONAL ANTIBODIESMAB 4001 5 100561 NEWMAB 4002 5 100565 NEWMAB 4003 5 100562 NEWMAB 4004 5 100563 NEWMAB 4005 5 100564 NEWMAB 4006 5 100567 NEW
RECOMBINANT ANTIGENPCT antigen 610080 NEW
Infl
am
matio
n
* Concentration: mg/ml (+/- 10%)16
INFLAMMATION PRODUCT CONC.* REF.
Serum amyloid A (SAA)
is associated with HDL during inflammatory states. The blood level of SAA increases dramatically in response to tissue injury and inflammation.
MONOCLONAL ANTIBODIESMAB 2201 5 100279MAB 2203 5 100289
RECOMBINANT ANTIGENSAA antigen 610070
Transferrin
regulates the amount of free iron in circulation. Transferrin concentration elevates in anemia, but can be also be used to diagnose other clinical conditions.
MONOCLONAL ANTIBODIESMAB 3104 5 100525MAB 3105 5 100440MAB 3106 5 100474
Trypsinogen-2
is the precursor form of the pancreatic enzyme trypsin. Determination of urine trypsinogen-2 is a useful test to detect acute pancreatitis and to evaluate disease severity.
MONOCLONAL ANTIBODIESMAB 8603 5 100107MAB 8607 5 100108
RECOMBINANT ANTIGENTrypsinogen-2 antigen 610020
All product specifications can be found online: www.medixbiochemica.com 17
KIDNEY MARKERS PRODUCT CONC.* REF.
Cystatin C
is an emerging renal biomarker. It is used for the diagnosis of chronic kidney disease. Cystatin C has also been associated with an increased risk of cardiovascular disease and heart failure.
MONOCLONAL ANTIBODIESMAB 10001 5 TBDMAB 10002 5 TBDMAB 10003 5 TBDMAB 10004 5 TBDMAB 10005 5 TBD
RECOMBINANT ANTIGENCystatin C antigen 610100 NEW
Neutrophil gelatinase-associated lipocalin (NGAL)
also known as Lipocalin-2 (LCN2), is used as a biomarker of kidney injury, and has also been shown to play a role in cancer and cardiovascular events.
MONOCLONAL ANTIBODIESMAB 4202 5 100579 NEWMAB 4203 5 100580 NEWMAB 4204 5 100581 NEWMAB 4205 5 100582 NEW
RECOMBINANT ANTIGENNGAL antigen 610012
Kid
ne
y
ma
rke
rs
UPCOMINGUPCOMINGUPCOMINGUPCOMINGUPCOMING
Infl
am
matio
n
* Concentration: mg/ml (+/- 10%)18
SEROLOGY PRODUCT CONC.* REF.
Immunoglobulin A (IgA)
is an antibody which plays a critical role in mucosal immunity. IgA has two subclasses (IgA1 and IgA2) and can exist in a dimeric form called secretory IgA (sIgA).
MONOCLONAL ANTIBODYMAB 8203 5 100101
Immunoglobulin E (IgE)
plays an important role in allergy and defence against parasites. IgE is a class of antibody that has only been found in mammals.
MONOCLONAL ANTIBODIESMAB 8510 5 100429MAB 8516 1 100105MAB 8518 1 100106
HRP-CONJUGATED ANTIBODYHRP 8510 8510-HRP
Immunoglobulin G (IgG)
antibodies are involved in the secondary immune response. IgG is a monomeric immunoglobulin consisting of four subclasses and constituting 75% of serum immunoglobulins in humans.
MONOCLONAL ANTIBODIESMAB 7701 5 100087MAB 7701 10 100152
HRP-CONJUGATED ANTIBODYHRP 7701 7701-HRP
Immunoglobulin M (IgM)
is involved in primary immune response. IgM is a basic antibody that first appears in response to exposure to antigen and indicates recent infection in patient’s serum.
MONOCLONAL ANTIBODYMAB 7408 5 100084
HRP-CONJUGATED ANTIBODYHRP 7408 7408-HRP
All product specifications can be found online: www.medixbiochemica.com 19
THYROID PRODUCT CONC.* REF.
Thyroglobulin
is used in the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer.
MONOCLONAL ANTIBODIESMAB 2802 5 100331MAB 2803 5 100332MAB 2804 5 100333MAB 2805 5 100334
Thyroid-stimulating hormone (TSH)
is a peptide hormone which regulates the endocrine function of the thyroid gland. Abnormal TSH levels may lead to hyperthyroidism or hypothyroidism.
MONOCLONAL ANTIBODIESMAB 5401 1 100023MAB 5403 5 100024MAB 5404 5 100026MAB 5405 1 100030MAB 5407 5 100254MAB 5408 1 100033
TSH complexMAB 5409 5 100034
FAB-FRAGMENTSFAB 5404 600020FAB 5405 600021FAB 5409 600023
Thyroxine (T4)
is the major hormone produced by the thyroid gland. Thyroxine is a prohormone and a reservoir for the active thyroid hormone (T3). Thyroxine is measured from blood to diagnose thyroid disorders.
MONOCLONAL ANTIBODYMAB 6901 5 100348
Thyro
idSe
rolo
gy
* Concentration: mg/ml (+/- 10%)20
TUMOR MARKERS PRODUCT CONC.* REF.
Alpha-fetoprotein (AFP)
is a major plasma protein produced by fetus. AFP is measured in pregnancy as a screening test for a subset of developmental abnormalities. It is also used as a biomarker to detect a subset of tumors.
MONOCLONAL ANTIBODIESMAB 5107 1 100014MAB 5108 5 100015
Cancer antigen 15-3 (CA15-3)
is defined by the use of two monoclonal antibodies, one specific for MUC-1 protein core and another specific for a carbohydrate epitope on the MUC-1 protein. CA15-3 is a widely used serum marker for breast cancer monitoring.
Antibodies 4401, 4402, 4403, and 4404 recognize the MUC-1 core protein of CA15-3.
MONOCLONAL ANTIBODIESMAB 4401 5 100591 NEWMAB 4402 5 100595 NEWMAB 4403 5 100583 NEWMAB 4404 5 100584 NEW
Cancer antigen 125 (CA125)
is a peptide epitope on the mucin glycoprotein MUC16. CA125 is the most widely used serum biomarker to monitor epithelial ovarian cancer. It is also used for the differential diagnosis of pelvic masses.
MONOCLONAL ANTIBODIESMAB 4601 5 100598 NEW
MAB 4602 5 100628 NEW
Carbohydrate antigen 19-9 (CA19-9)
is a tumor biomarker also called Sialyl Lewis A. Serum level measurements of CA19-9 are widely used in pancreatic cancer patients for monitoring their response to cancer treatments.
MONOCLONAL ANTIBODIESMAB 4701 5 100609 NEW
Carcinoembryonic antigen (CEA)
is normally produced during fetal development. It has been used as a tumor marker for colorectal cancer and several carcinomas.
MONOCLONAL ANTIBODIESMAB 5905 1 100044MAB 5909 5 100428MAB 5910 5 100047MAB 5911 1 100048MAB 5912 1 100049
All product specifications can be found online: www.medixbiochemica.com 21
TUMOR MARKERS PRODUCT CONC.* REF.
CYFRA21-1
is a fragment of Cytokeratin 19. Serum CYFRA21-1 has been used as a tumor marker of different origins and especially in non-small cell lung cancer.
MONOCLONAL ANTIBODIESMAB 1602 5 100220MAB 1603 5 100221MAB 1604 5 100222MAB 1605 5 100223MAB 1608 5 100518MAB 1610 5 100519MAB 1611 5 100520
Hemoglobin (Hb)
is the iron-containing oxygen-transport metalloprotein in the red blood cells. Hemoglobin carries oxygen from the lungs to the body tissue. Changes from the normal values usually indicate abnormalities, such as anemia.
MONOCLONAL ANTIBODIESMAB 7202 5 100079MAB 7204 5 100080
Human epididymis protein 4 (HE4)
also known as WAP four-disulfide core domain protein 2, is a 124 amino acid long protease inhibitor. Serum HE4 is often measured together with CA125 to monitor progression of epithelial ovarian cancer after treatment.
MONOCLONAL ANTIBODIESMAB 4501 5 100589 NEWMAB 4502 5 100592 NEWMAB 4503 5 100608 NEWMAB 4505 5 100593 NEWMAB 4506 5 100594 NEW
Neuron-specific enolase (NSE)
has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma.
MONOCLONAL ANTIBODIESMAB 9601 5 100388MAB 9602 5 100408
Tum
or
ma
rke
rs
22 * Concentration: mg/ml (+/- 10%)
TUMOR MARKERS PRODUCT CONC.* REF.
Pepsinogen (PG I & II)
is the pro-form of pepsin. It is produced in the stomach and secreted into the gastric lumen, but a small amount also into the blood. Alterations in the serum pepsinogen concentration may indicate gastric abnormalities.
MONOCLONAL ANTIBODIESPG I MAB 8003 5 100120PG I MAB 8009 1 100093PG I MAB 8015 5 100143PG I MAB 8016 1 100095
PG II MAB 8101 5 100097PG II MAB 8102 1 100098PG II MAB 8103 5 100121
HRP-CONJUGATED ANTIBODIESHRP 8003 8003-HRPHRP 8102 8102-HRP
RECOMBINANT ANTIGENSPG I antigen 610000PG II antigen 610001
Prostate-specific antigen (PSA)
is a protein produced by the cells of the prostate gland. PSA is often elevated in the presence of prostate cancer and in other prostate disorders. Free PSA is a form of PSA that does not become attached to other blood proteins. Decreased levels of free PSA may indicate prostate cancer.
MONOCLONAL ANTIBODIES
MAB 8301 5 100102MAB 8311 1 100103MAB 8312 5 100139
Free PSAMAB 8313 5 100488
23
CARDIOVASCULAR MARKERS:
cTnI antigen ref. 610102cTnT antigen ref. 610101 FABP3 antigen ref. 610043Galectin-3 antigen ref. TBDMyoglobin antigen ref. 610030NT-proBNP antigen ref. 610090proBNP antigen ref. 710017S100B antigen ref. 710014ST2 antigen ref. 710020 DIABETES & METABOLISM:
Adiponectin antigen ref. 710013ApoA1 antigen ref. 710012Lactoferrin antigen ref. 710016 INFECTIOUS DISEASES:
HCoV OC43 N antigen ref. 610040HCoV NL63 N antigen ref. 610041HCoV HKU1 N antigen ref. 610042HCoV 229E N antigen ref. 610091HRP2 antigen ref. 610081
INFLAMMATION:
S100A8/S100A9 antigen ref. 610061S100A8 antigen ref. 710018 S100A9 antigen ref. 710019IL-6 antigen ref. 710015 Lactoferrin antigen ref. 710016 PCT antigen ref. 610080SAA antigen ref. 610070Trypsinogen-2 antigen ref. 610020 KIDNEY MARKERS:
Cystatin C antigen ref. 610100NGAL antigen ref. 610012 TUMOR MARKERS:
PG I antigen ref. 610000PG II antigen ref. 610001
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