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Before a cell gets too large, a growing cell divides forming two “daughter cells” Cell division process by which a cell divides into two new daughter cells Before cell division begins, DNA replicates (copies) itself One copy for each new cell
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Friday Feb 10th Day E
• Collect remaining Wequests• Begin 10.2
– Notes– Video Clip– Handout
HW – Study for 10.1 QuizChapter 10 VocabularySurface area/volume problems
Chapter 10.2Chapter 10.2Cell Division
Cell Division
• Before a cell gets too large, a growing cell divides forming two “daughter cells”
• Cell division process by which a cell divides into two new daughter cells
• Before cell division begins, DNA replicates (copies) itselfOne copy for each new cell
Division in Prokaryotes• After DNA is copied, cell splits in two
Each new cell contains a copy of the DNA called binary fissionbinary fission– Example of asexual reproduction
Binary Fission in a Paramecium
Division in Eukaryotes
• Occurs in two main stages– 1st stage division of the nucleus = mitosis– 2nd stage division of the cytoplasm = cytokinesis
• Helps multicellular organisms grow and develop
Chromosomes Structures that carry genetic information
– Made up of DNA and protein (histones)
• Humans have 46 total (23 pairs) (other organisms have different numbers)
Chromosomes• While the cell is “resting”, you cannot see the
chromosomes. It is unwoundCalled chromatin
chromatin chromosome
(1) Double-stranded DNA. (2) Chromatin strand (DNA with histones). (3) Chromatin during interphase with centromere. (4) Condensed chromatin during prophase. (Two copies of the DNA molecule are now present) (5) Chromosome during metaphase.
Chromosomes• While the cell is dividing, you can see the
chromosomes It is wound upMade of two sister chromatids connected by a
centromere
Chromosomes
Centromere
Sister Chromatid
The Cell Cycle• Occurs in eukaryotic
cells
It is the period of time from the beginning of one cell division to the beginning of the next
• Cell doubles its contents so that it is ready to divide into two completely independent cells
M phase
S phase
G1 phase
G2 phase
The Cell Cycle
Consists of 4 phases – 1. M phase – mitosis the division of the cell nucleus and cytokinesis– 2. G1 intense growth and activity; new proteins and organelles are made– 3. S phase copying of chromosomes– 4. G2 intense growth and activity; new proteins and organelles are made
• Shortest of the four phases
M phase
S phase
G1 phase
G2 phase
M phase
• Cell division– Process in which the cell divides
into two independent cells daughter cellsdaughter cells
– Process is called mitosismitosis in eukaryotes and binary fissionbinary fission in prokaryotes
Cell Cycle Rates
Cells do not move through the cell cycle at the same rate– Average rate of a human cell is once every 20
hours
Mitosis
• Time of cell division
• Divided into four main phases– 1. Prophase– 2. Metaphase– 3. Anaphase– 4. Telophase
Centrioles
Chromatin
Interphase
Nuclear envelope
Cytokinesis
Nuclear envelope reforming
Telophase
Anaphase
Individual chromosomes
Metaphase
Centriole
Spindle
CentrioleChromosomes
(paired chromatids)
Prophase
Centromere
Spindle forming
Section 10-2Mitosis and Cytokinesis
1. Prophase• 1. Appearance of chromosomes
– 2 sister chromatids attached at the centromere
• 2. Nuclear membrane begins to breakdown
• 3. Spindle begins to form– Purpose is to pull chromatids apart
• 4. Spindle attaches to the chromosomes at the centromere– In animals, spindle is made by the centriole
Plants lack centrioles
Spindle forming
Centromere
Chromosomes (paired chromatids)
2. Metaphase
• 1. Chromosomes line up in the middle of the cell
Centriole
Centriole
Spindle
3. Anaphase
• 1. Centromeres split
• 2. Sister chromatids are pulled to the opposite ends of the cell by the spindle
Individual chromosomes
4. Telophase
• 1. Spindle breaks down
• 2. Nuclear envelope reforms around the chromosomes
• 3. Chromosomes unwind to chromatin again
Nuclear envelope reforming
Cytokinesis• Division of the cytoplasm
• In animals the cell pinches in at the middle to create two new cells
• In plants a cell plate is created in the middle of the cell
Centrioles
Chromatin
Interphase
Nuclear envelope
Cytokinesis
Nuclear envelope reforming
Telophase
Anaphase
Individual chromosomes
Metaphase
Centriole
Spindle
CentrioleChromosomes
(paired chromatids)
Prophase
Centromere
Spindle forming
Section 10-2Mitosis and Cytokinesis
Videos
• Animal Cell Mitosis
• Animal Cell Cytokinesis
• Animal Cell Mitosis: Interactive
• How the Cell Cycle Works
Friday Feb 10th Day E
• Collect remaining Wequests• Begin 10.2
– Notes– Video Clip– Handout
HW – Study for 10.1 QuizChapter 10 VocabularySurface area/volume problems