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Cambridge University Press 978-1-107-61238-9 — Fundamentals of Anaesthesia Edited by Ted Lin , Tim Smith , Colin Pinnock , Edited in association with Chris Mowatt Table of Contents More Information www.cambridge.org © in this web service Cambridge University Press Contents List of contributors page ix Preface to the rst edition xi Preface to the second edition xii Preface to the third edition xiii Preface to the fourth edition xiv Acknowledgements xv List of abbreviations xvii Section 1: Clinical anaesthesia 1 Chris Mowatt 1 Preoperative management 1 Gwenda Cavill and Karen Kerr 2 Conduct of anaesthesia 29 Chris Mowatt 3 Intraoperative management 46 Chris Mowatt 4 Postoperative management 57 Tina McLeod 5 Special patient circumstances 79 Colin Pinnock, Robert Haden and Dan Bailey 6 The surgical insult 128 Colin Pinnock and Robert Haden 7 Regional anaesthesia 139 Barrie Fischer and Oscar Domingo i Bosch 8 Principles of resuscitation 170 Anita Stronach 9 Major trauma 195 Jerry Nolan Section 2: Physiology 210 Ted Lin 10 Cellular physiology 210 Ted Lin 11 Body uids 232 Mahesh Chaudhari 12 Haematology and immunology 247 Jeff Neilson and Ted Lin 13 Muscle physiology 269 Edwin Mitchell 14 Cardiac physiology 282 Justiaan Swanevelder 15 Physiology of the circulation 315 Ted Lin 16 Renal physiology 344 Alexander Ng 17 Respiratory physiology 371 Bal Appadu and Ted Lin 18 Physiology of the nervous system 404 Peter Featherstone, Anand Sardesai and Arun Gupta 19 Physiology of pain 431 Ted Lin 20 Gastrointestinal physiology 454 Matthew Faulds and Nick Morgan-Hughes 21 Metabolism and temperature regulation 466 Smita Gohil and Ted Lin 22 Endocrine physiology 491 Jo James 23 Physiology of pregnancy 512 Mary Mushambi 24 Fetal and newborn physiology 531 Andrew Wolf Section 3: Pharmacology 537 Tim Smith 25 Physical chemistry 537 Tim Smith

Contentsassets.cambridge.org/97811076/12389/toc/9781107612389_toc.pdf · 39 Gastrointestinal pharmacology 721 Tim Smith 40 Intravenous uids 727 Tim Smith 41 Pharmacology of haemostasis

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Cambridge University Press978-1-107-61238-9 — Fundamentals of Anaesthesia

Edited by Ted Lin , Tim Smith , Colin Pinnock , Edited in association with Chris Mowatt

Table of Contents

More Information

www.cambridge.org© in this web service Cambridge University Press

Contents

List of contributors page ix

Preface to the first edition xi

Preface to the second edition xii

Preface to the third edition xiii

Preface to the fourth edition xiv

Acknowledgements xv

List of abbreviations xvii

Section 1: Clinical anaesthesia 1

Chris Mowatt

1 Preoperative management 1

Gwenda Cavill and Karen Kerr

2 Conduct of anaesthesia 29

Chris Mowatt

3 Intraoperative management 46

Chris Mowatt

4 Postoperative management 57

Tina McLeod

5 Special patient circumstances 79

Colin Pinnock, Robert Haden and

Dan Bailey

6 The surgical insult 128

Colin Pinnock and Robert Haden

7 Regional anaesthesia 139

Barrie Fischer and Oscar Domingo

i Bosch

8 Principles of resuscitation 170

Anita Stronach

9 Major trauma 195

Jerry Nolan

Section 2: Physiology 210

Ted Lin

10 Cellular physiology 210

Ted Lin

11 Body fluids 232

Mahesh Chaudhari

12 Haematology and immunology 247

Jeff Neilson and Ted Lin

13 Muscle physiology 269

Edwin Mitchell

14 Cardiac physiology 282

Justiaan Swanevelder

15 Physiology of the circulation 315

Ted Lin

16 Renal physiology 344

Alexander Ng

17 Respiratory physiology 371

Bal Appadu and Ted Lin

18 Physiology of the nervous system 404

Peter Featherstone, Anand Sardesai and

Arun Gupta

19 Physiology of pain 431

Ted Lin

20 Gastrointestinal physiology 454

Matthew Faulds and Nick

Morgan-Hughes

21 Metabolism and temperature regulation 466

Smita Gohil and Ted Lin

22 Endocrine physiology 491

Jo James

23 Physiology of pregnancy 512

Mary Mushambi

24 Fetal and newborn physiology 531

Andrew Wolf

Section 3: Pharmacology 537

Tim Smith

25 Physical chemistry 537

Tim Smith

Cambridge University Press978-1-107-61238-9 — Fundamentals of Anaesthesia

Edited by Ted Lin , Tim Smith , Colin Pinnock , Edited in association with Chris Mowatt

Table of Contents

More Information

www.cambridge.org© in this web service Cambridge University Press

26 Pharmacodynamics 550

Tim Smith

27 Pharmacokinetics 562

Tim Smith

28 Mechanisms of drug action 578

Sue Hill

29 Anaesthetic gases and vapours 594

Tim Smith

30 Hypnotics and intravenous anaesthetic

drugs 606

Tim Smith

31 Analgesic drugs 621

Ian Power and Michael Paleologos

32 Neuromuscular blocking agents 647

Tim Smith

33 Local anaesthetic agents 658

Tim Smith

34 Central nervous system pharmacology 667

Tim Smith

35 Autonomic nervous system pharmacology 680

Tim Smith

36 Cardiovascular pharmacology 695

Tim Smith

37 Respiratory pharmacology 708

Tim Smith

38 Endocrine pharmacology 714

Tim Smith

39 Gastrointestinal pharmacology 721

Tim Smith

40 Intravenous fluids 727

Tim Smith

41 Pharmacology of haemostasis 733

Tim Smith

42 Antimicrobial therapy 739

Jim Stone

43 Clinical trials and basic statistics 754

Leon Vries and Ted Lin

Section 4: Physics and clinical

measurement 782

Ted Lin

44 Applied physics 782

Ted Lin and Rajani Annamaneni

45 Clinical measurement 845

Ted Lin and Rajani Annamaneni

46 Anaesthetic equipment 893

Ted Lin and Rajani Annamaneni

Index 932

viii Contents