• Genetic Disorders»By: Mr. Robey

Each egg and each sperm

Causes of Genetic Disorders:Radiation or chemicals cause changes

in the order of DNA “letters”

-Mutated DNA can be inherited by the child (in the sperm or egg)

-Damage can occur to the egg or sperm producing cells (ovaries or testes)

-Damage can occur to the sperm or egg

-Damage can occur to the embryo after conception

• Types of DNA mutations:• A genetic disorder can result when:

• A single gene is mutated

• Several genes are mutated, all working together

• One or more genes is missing

• An entire chromosome is missing

• There is an extra chromosome

•Skin Disorders

Albinism

Malignant Melanoma

Xeroderma Pigmentosum

Bloom Syndrome

Porphyria

Amyloidosis

•Eye Disorders

Color blindness

Retinitis Pigmentosum

Retinoblastoma

•Bone/Joint Disorders

Multiple Exostosis

Osteogenesis Imperfecta

Fibrodysplasia Ossificans Progressiva

Apert Syndrome

Edward’s Syndrome

Polydactyly

•Muscle Disorders

Muscular Dystrophy

Refsum Disease

•Hair Disorders

Male Pattern Baldness

Alopecia

•Blood Disorders

Sickle Cell Disease

Hemophilia

Severe Combined Immunodeficiency

Polycystic Kidney Disease

•Mental Disorders

Down Syndrome

Angelman Syndrome

Cri du Chat Syndrome

•Growth Disorders

Pituitary Dwarfism

Diastrophic Dysplasia

•Premature Aging Disorders

Progeria

Cockayne Syndrome