Genomics of Large Marine Metazoans || Front Matter

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June 2008 THE

Volume 214 Number 3

BIOLOGICAL

BULLETIN

Genomics of Large Marine Metazoans

N&fr.

? ?T% T Biological

JltjL J3 J? Discovery in Woods Hole

Published by the Marine Biological laboratory



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^t??lished names sucl? as T.H. Morgan, Jacques Loeb,

|:FrankK. Lillie, Julien Huxley, C. Ladd Prosser, Libbie 4?

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Cover

The "virtual" symposium in this issue, "Genomics

of Large Marine Metazoans," collects current re

search on the gene catalogs and genomic structure

of marine organisms. This emerging dimension of

marine science is sure to become more fully popu lated as the cost of genome sequencing decreases.

The cover shows in a small way the huge variety of

organisms that exist in the many corners of the

marine habitat. Each of these varied organisms rep resents a solution to the problem of living in its

environment. These "natural experiments," or evo

lutionary outcomes, are often very clearly docu

mented within the genome of each organism.

The images: The individual panels depict some of

the animals considered in the symposium papers. The background is a microscope field of four-cell

lamprey embryos (Petromyzon marinus), each of

which has been injected with a fluorescent marker

in one cell at the two-cell stage. The central panel

shows two adult star anemones, Nematostella vec

tensis; one is undergoing asexual division and the

other has a clutch of spawned eggs nearby. Clock

wise from top: a hydrothermal vent tube worm,

Ridgeia piscesae, with the anterior region emerging from the tube. The late larval stage of a sea urchin,

Strongylocentrotus purpuratus. The interior of the

brood chamber of a sponge, Amphimedon queens landica, showing embryos in the early phases of

development. An adult of an enteropneust worm,

Saccoglossus kowalevskii.

Photo credits: Petromyzon marinus, Tatjana Sauka

Spengler (California Institute of Technology); Ne

matostella vectensis, Adam Reitzel (Woods Hole

Oc?anographie Institution); Ridgeia piscesae, Peter

Batson (Deep Ocean Expeditions, Inc.); Strongylo centrotus purpuratus, Jonathan Rast (University of

Toronto); Amphimedon queenslandica, Bryony Fa

hey (University of Queensland); Saccoglossus kowa

levskii, Chris Lowe (University of Chicago). Cover

design: Beth Liles (Marine Biological Laboratory).



THE

BIOLOGICAL BULLETIN

JUNE 2008

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Invertebrates of the Woods Hole Region

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Online submission of manuscripts to

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CONTENTS

Volume 214, No. 3: June 2008

GENOMICS OF LARGE MARINE METAZOANS

Cameron, R. Andrew, and Jonathan P. Rast

Biological Bulletin Virtual Symposium: genomics of

large marine metazoans. 203

Fahey, Bryony, Claire Larroux, Ben J. Woodcroft, and

Bernard M. Degnan Does the high gene density in the sponge NK homeobox gene cluster reflect limited regulatory

capacity?. 205

Magie, Craig R., and Mark Q. Martindale

Cell-cell adhesion in the Cnidaria: insights into the

evolution of tissue morphogenesis. 218

Reitzel, Adam M., James C. Sullivan, Nikki Traylor

Knowles, and John R. Finnerty Genomic survey of candidate stress-response genes in

the estuarine anemone Nematostella vectensis . 233

Nyholm, Spencer V., Julie Robidart, and Peter R.

Girguis Coupling metabolite flux to transcriptomics: insights into the molecular mechanisms underlying primary

productivity by the hydrothermal vent tubeworm

Ridgeia piscesae. 255

Materna, Stefan C, and R. Andrew Cameron

The sea urchin genome as a window on function ... 266

Rast, Jonathan P., and Cynthia Messier-Solek

Marine invertebrate genome sequences and our

evolving understanding of animal immunity. 274

Freeman, R. M., Jr., M. Wu, M.-M. Cordonnier-Pratt,

L. H. Pratt, C. E. Gruber, M. Smith, E. S. Lander, N.

Stange-Thomann, C. J. Lowe, J. Gerhart, and M. K?rschner

cDNA sequences for transcription factors and signal

ing proteins of the hemichordate Saccoglossus kowa

levskii: efficacy of the expressed sequence tag (EST)

approach for evolutionary and developmental stud

ies of a new organism. 284

Sauka-Spengler, Tatjana, and Marianne Bronner-Fraser

Insights from a sea lamprey into the evolution of

neural crest gene regulatory network . 303

RAPID COMMUNICATION

Gaylord, Brian

Hydrodynamic context for considering turbulence

impacts on external fertilization . 315

ECOLOGY AND EVOLUTION

Hoover, Cindi A., Marc Slattery, Nancy M. Targett, and Adam G. Marsh

Transcriptome and metabolite responses to pr?da tion in a South Pacific soft coral . 319

Same o to, Jessica A., and Anna Metaxas

Can salinity-induced mortality explain larval vertical

distribution with respect to a halocline? . 329

* * *

Index for Volume 214 339



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Genomics of Large Marine Metazoans || Front Matter