GK-12 Saturday Workshop I

October 16, 2010RS: Amy Zimmerman

CTs: Roy Center, Lee Kelly

Genetic Transformation:

Process and Applications

Why teach transformation???Powerful tool used widely in researchApply scientific methods and conceptsIntroduce model organismsHands-on laboratory investigationReal-world connectionsStandards based (*HS)

Overview of Lesson ModuleGenetic Transformation LectureModeling Transformation ActivityGlowing Bacteria Laboratory ExerciseExtension Activities

Transformation Efficiency; Gene Therapy

Lesson ObjectivesIdentify elements of good experimental

designCreate, analyze, and interpret dataExecute basic microbiology techniquesUnderstand the process and purpose of

transformationRecognize real-life applications of

biotechnology

Standards Adressed7th Grade Life

ScienceCell Biology 1aGenetics 2a,eEvolution 3b

High School BiologyCell Biology 1a,c,dGenetics 5a,c,d*,e*Evolution 7a, 8a

Investigation and Experimentation

Prior KnowledgeScientific Inquiry and Experimental DesignCell Structure and Function

Membrane propertiesGenetics

Genes, DNA, Proteins, TraitsBacteria

Structure and reproduction

Implementation Timeline

Day 1

Genetic Transformation Lecture

Day 2

Modeling Transformation Activity

Day 3

Glowing Bacteria, Part 1

Day 4

Glowing Bacteria, Part 2Transformation Efficiency

Day 5

Gene Therapy Activity

AssessmentTransformation successHandouts and lab write-upExtension activities