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Global Appraisal of Individual Needs (GAIN): A Standardized Biopsychosocial Assessment Tool Michael Dennis, Ph.D. Chestnut Health Systems, Normal, IL Workshop at 16th Annual Drug Court Training Conference of the National Association of Drug Court Professionals, Boston, MA, June 3, 2010.. This presentation reports on treatment & research funded by the Center for Substance Abuse Treatment (CSAT), Substance Abuse and Mental Health Services Administration (SAMHSA) under contracts 270-2003-00006 and 270- 07-0191, as well as several individual CSAT, NIAAA, NIDA and private foundation grants. The opinions are those of the author and do not reflect official positions of the consortium or government. Available on line at www.chestnut.org/LI/Posters or by contacting Joan Unsicker at 448 Wylie Drive, Normal, IL 61761, phone: (309) 451-7801, Fax: (309) 451-7763, e-mail: [email protected]

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Global Appraisal of Individual Needs (GAIN):A Standardized Biopsychosocial

Assessment Tool

Michael Dennis, Ph.D.Chestnut Health Systems,

Normal, IL

Workshop at 16th Annual Drug Court Training Conference of the National Association of Drug Court Professionals, Boston, MA, June 3, 2010.. This presentation reports on

treatment & research funded by the Center for Substance Abuse Treatment (CSAT), Substance Abuse and Mental Health Services Administration (SAMHSA) under

contracts 270-2003-00006 and 270-07-0191, as well as several individual CSAT, NIAAA, NIDA and private foundation grants. The opinions are those of the author and do not reflect official positions of the consortium or government. Available on line at

www.chestnut.org/LI/Posters or by contacting Joan Unsicker at 448 Wylie Drive, Normal, IL 61761, phone: (309) 451-7801, Fax: (309) 451-7763, e-mail:

[email protected]

1. Provide an overview of the role of the GAIN as a piece of infrastructure in support the move toward both evidence based practice and practice based evidence

2. Describe each of the measures, the reports that they use to help the assessment guide clinical decision making and illustrate how they provide a successively more detailed picture of client needs

3. Highlight our current work to using actuarial estimates of outcomes to improve placement decisions

4. Summarize the status of efforts to make the data available for secondary analysis and translate the software, measures and reports from English into Spanish, French, Portuguese and other languages

Goals of this Presentation are to

Part 1. Provide an overview of the role of the GAIN as a piece of infrastructure in support the move toward both evidence based practice and practice based evidence

The Global Appraisal of Individual Needs (GAIN) is ..

A family of instruments ranging from screening, to quick assessment to a full Biopsychosocial and monitoring tools

Designed to integrate clinical and research assessment

Designed to support clinical decision making at the individual client level

Designed to support evaluation and planning at program level

Designed to support secondary analyses and comparisons across individuals and programs

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No of GAIN Sites

None (Yet)

1 to 14

15 to 30

31 to 164

GAIN Collaborators in the U.S (4/10)

State or Regional System

GAIN-Short Screener

GAIN-Quick

GAIN-Full

3/10 5

Some numbers as of April 2010

1,368 Licensed GAIN administrative units from 49 states (all by ND) and 7 countries

2,853 users in 405 Agencies using GAIN ABS 43,968 intake assessments (largest in field) 22,045 (88% w 1+ follow-up) from 219 CSAT grantees

(largest follow-up data set in field) 22 states, 12 Federal, 6 provincial, and 3 foundations

mandate or strongly encourage its use 4 dozen researchers have published 186 GAIN-related

research publications to date Medicaid, Health Canada, several states, and private

insurance systems accept it as evidence based

6

So what does it mean to move the field towards Evidence Based Practice (EBP)?

Introducing explicit intervention protocols that are– Targeted at specific problems/subgroups and outcomes– Having explicit quality assurance procedures to cause adherence

at the individual level and implementation at the program level

Introducing reliable and valid assessment that can be used – At the individual level to immediately guide clinical judgments

about diagnosis/severity, placement, treatment planning, and the response to treatment

– At the program level to drive program evaluation, needs assessment, performance monitoring and long term program planning

Having the ability to evaluate client and program outcomes – For the same person or program over time, – Relative to other people or interventions

Key Issues that we try to address with the GAIN Instruments and Coordinating Center

1. High turnover workforce with variable education background related to diagnosis, placement, treatment planning and referral to other services

2. Heterogeneous needs and severity characterized by multiple problems, chronic relapse, and multiple episodes of care over several years

3. Lack of access to or use of data at the program level to guide immediate clinical decisions, billing and program planning

4. Missing, bad or misrepresented data that needs to be minimized and incorporated into interpretations

5. Lack of Infrastructure that is needed to support implementation and fidelity

1. High Turnover Workforce with Variable Education

Questions spelled out and simple question format

Lay wording mapped onto expert standards for given area

Built in definitions, transition statements, prompts, and checks for inconsistent and missing information.

Standardized approach to asking questions across domains

Range checks and skip logic built into electronic applications

Formal training and certification protocols on administration, clinical interpretation, data management, coordination, local, regional, and national “trainers”

Above focuses on consistency across populations, level of care, staff and time

On-going quality assurance and data monitoring for the reoccurrence or problems at the staff (site or item) level

Availability of training resources, responses to frequently asked questions, and technical assistance

Outcome: Improved Reliability and Efficiency

2. Heterogeneous Needs and Severity

Multiple domains Focus on most common

problems Participant self description of

characteristics, problems, needs, personal strengths and resources

Behavior problem recency, breadth , and frequency

Utilization lifetime, recency and frequency

Dimensional measures to measure change with interpretative cut points to facilitate decisions

Items and cut points mapped onto DSM for diagnosis, ASAM for placement, and to multiple standards and evidence- based practices for treatment planning

Computer generated scoring and reports to guide decisions

Treatment planning recommendations and links to evidence-based practice

Basic and advanced clinical interpretation training and certification

Outcome: Comprehensive Assessment

3. Lack of Access to or use of Data at the Program Level

Data immediately available to support clinical decision making for a case

Data can be transferred to other clinical information system to support billing, progress reports, treatment planning and on-going monitoring

Data can be exported and cleaned to support further analyses

Data can be pooled with other sites to facilitate comparison and evaluation

PC and web based software applications and support

Formal training and certification on using data at the individual level and data management at the program level

Data routinely pooled to support comparisons across programs and secondary analysis

Over three dozen scientists already working with data to link to evidence-based practice

Outcome: Improved Program Planning and Outcomes

4. Missing, Bad or Misrepresented Data

Assurances, time anchoring, definitions, transition, and question order to reduce confusion and increase valid responses

Cognitive impairment check Validity checks on missing,

bad, inconsistency and unlikely responses

Validity checks for atypical and overly random symptom presentations

Validity ratings by staff

Training on optimizing clinical rapport

Training on time anchoring Training answering questions,

resolving vague or inconsistent responses, following assessment protocol and accurate documentation.

Utilization and documentation of other sources of information

Post hoc checks for on-going site, staff or item problems

Outcome: Improved Validity

5. Lack of Infrastructure

Direct Services

Training and quality assurance on administration, clinical interpretation, data management, follow-up and project coordination

Data management

Evaluation and data available for secondary analysis

Software support

Technical assistance and back up to local trainer/expert

Development

Clinical Product Development

Software Development

Collaboration with IT vendors (e.g., WITS)

Over 36 internal & external scientists and students

Workgroups focused on specific subgroup, problem, or treatment approach

Labor supply (e.g., consultant pool, college courses)

Outcome: Implementation with Fidelity

Across measures, the GAIN has a Common Factor Structure of Psychopathology

Source: Dennis, Chan, and Funk (2006) CFI=.92, RMSEA=.06 allowing for age

Alcohol and Other Drug Abuse, Dependence and Problem Use are Age Related

Source: 2002 NSDUH and Dennis & Scott, 2007, Neumark et al., 2000

0

10

20

30

40

50

60

70

80

90

100

12-13

14-15

16-17

18-20

21-29

30-34

35-49

50-64

65+Other drug or heavy alcohol use in the past year

Alcohol or Drug Use (AOD) Abuse or Dependence in the past year

Age

Severity Category

Over 90% of use and

problems start between the ages of

12-20

It takes decades before most recover or die

Per

cent

age

People with drug dependence die an

average of 22.5 years sooner than those

without a diagnosis

Co-occurring Mental Health Problems are Common, but the Type of Problems also Changes with Age

Source: Chan, YF; Dennis, M L.; Funk, RR. (2008). Prevalence and comorbidity of major internalizing and externalizing problems among adolescents and adults presenting to substance abuse treatment. Journal of Substance Abuse Treatment, 34(1) 14-24 .

Internalizing Disorders go up

with age

Externalizing Disorders go down

with age (but do NOT go away)

Progressive Continuum of Measurement (Common Measures)

Screening to Identify Who Needs to be “Assessed” (5-10 min)– Focus on brevity, simplicity for administration & scoring– Needs to be adequate for triage and referral– GAIN Short Screener for SUD, MH & Crime– ASSIST, AUDIT, CAGE, CRAFT, DAST, MAST for SUD– SCL, HSCL, BSI, CANS for Mental Health– LSI, MAYSI, YLS for Crime

Quick Assessment for Targeted Referral (20-30 min)– Assessment of who needs a feedback, brief intervention or referral for

more specialized assessment or treatment– Needs to be adequate for brief intervention– GAIN Quick – ADI, ASI, SASSI, T-ASI, MINI

Comprehensive Biopsychosocial (1-2 hours) – Used to identify common problems and how they are interrelated– Needs to be adequate for diagnosis, treatment planning and placement

of common problems– GAIN Initial (Clinical Core and Full)– CASI, A-CASI, MATE

Specialized Assessment (additional time per area)– Additional assessment by a specialist (e.g., psychiatrist, MD, nurse,

spec ed) may be needed to rule out a diagnosis or develop a treatment plan or individual education plan

– CIDI, DISC, KSADS, PDI, SCAN

Screener Quick C

omprehensive S

pecial

More E

xtensive / Longer/ E

xpensive

Longer assessments identify more areas of unmet need

40%

69%

98%

22%

13%

0%

22%

8%

0%

9%8%

1%3% 1%7%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

GAIN SS GAIN Q GAIN I

0 Reported

1 Prob.

2 Probs.

3 Probs.

4 Probs.

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

Most substance users have multiple problems

18

19

Part 2. Describe each of the measures, the reports that they use to help the assessment guide clinical decision making and illustrate how they provide a successively more detailed picture of client needs

Next slides will

Describe the difference in the breadth of information you get with different levels of assessment

Summarize validation studies to date

Illustrate the difference using data from a single sample (Reclaiming futures project)

Demonstrate that multi-morbidity is the norm and varies by type of client and program

GAIN-Short Screener (GSS)

Administration Time: A 3- to 5-minute screener Purpose: Used in general populations to

– identify or rule-out clients who will be identified as having any behavioral health disorders on the 60-120 min versions of the GAIN

– triage area of problem– serve as a simple measure of change– Easy for administration and interpretation by staff with minimal

training or direct supervision Mode: Designed for self- or staff-administration, with paper and pen,

computer, or on the web Scales: Four screeners for Internalizing Disorders, Externalizing

Disorders, Substance Disorders, Crime/Violence, and a Total

Response Set: Recency of 20 problems rated past month (3), 2-12 months ago (2), more than a year ago (1), never (0)

Interpretation: Combined by cumulative time period as: – Past month count (3s) to measure of change– Past year count (2s or 3s) to predict diagnosis– Lifetime count (1s, 2s or 3s) as a measure of peak severity– Can be classified within time period low (0), moderate (1-2)

or high (3)– Can also be used to classify remission as – Early (lifetime but not past month)– Sustained (lifetime but not past year)

Reports: Narrative, tabular, and graphical reports built into web based GAIN ABS and/or ASP application for local hosting

GAIN-Short Screener (GSS) (continued)

GAIN-Short Screener (GSS)

GAIN SS Psychometric Properties

Total Disorder Screener (TDScr)

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

Prevalence (% 1+ disorder)

Sensitivity (% w disorder above)

Specificity (% w/o disorder below)

(n=6194 adolescents)

Low Mod. High

At 3 or more symptoms we get 99% prevalence, 91% sensitivity, & 89% specificity

Using a higher cut point increases prevalence and specificity, but

decreases sensitivity

Total score has alpha of .85 and is

correlated .94 with full GAIN version

Source: Dennis et al 2006

GSS Performance by Subscale and Disorders

Prevalence Sensitivity Specificity Screener/Disorder 1+ 3+ 1+ 3+ 1+ 3+ Internal Disorder Screener (0-5) Any Internal Disorder 81% 99% 94% 55% 71% 99% Major Depression 56% 87% 98% 72% 54% 94% Generalized Anxiety 32% 56% 100% 83% 44% 83% Suicide Ideation 24% 43% 100% 84% 41% 79% Mod/High Traumatic Stress 60% 82% 94% 60% 55% 90%

External Disorder Screener (0-5) Any External Disorder 88% 97% 98% 67% 75% 96% AD, HD or Both 65% 82% 99% 78% 51% 85% Conduct Disorder 78% 91% 98% 70% 62% 90%

Substance Use Disorder Screener (0-5) Any Substance Disorder 96% 100% 96% 68% 73% 100% Dependence 65% 87% 100% 91% 30% 82% Abuse 30% 13% 89% 25% 14% 28%

Crime Violence Screener (0-5) Any Crime/Violence 88% 99% 94% 49% 76% 99% High Physical Conflict 31% 46% 100% 70% 38% 77% Mod/High General Crime 85% 100% 94% 51% 71% 100%

Total Disorder Screener (0-5)Any Disorder 97% 99% 99% 91% 47% 89% Any Internal Disorder 58% 63% 100% 98% 8% 28% Any External Disorder 68% 75% 100% 99% 10% 37% Any Substance Disorder 89% 92% 99% 92% 20% 51% Any Crime/Violence 68% 73% 100% 96% 10% 32%

Recommend Triage as

0=Not likely1-2 Possible3+=Likely

Moderate (1+) gives best result

for sensitivity

High (3+) gives best result for

specificity

GAIN SS Total Score is Correlated With Level Of Care Placement: Adolescents

0%

1%

2%

3%

4%

5%

6%

7%

8%

9%

10%

11%

0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20

TDScr Score

% w

ithi

n L

evel

of

Car

e an

d A

ge G

roup OP/IOP (n=2499)

Residential (n=1965)

Low

Mod High ->OP/IOP

Median=6.0Residential

Median=10.5

GAIN SS Total Score is Correlated With Level Of Care Placement: Adults

GAIN SS Can Also be Used for Monitoring

109

11

910

8

32 2

0

4

8

12

16

20

Intake 3Mon

6Mon

9Mon

12Mon

15Mon

18Mon

21Mon

24Mon

Total Disorder Screener (TDScr)

12+ Mon.s ago (#1s)

2-12 Mon.s ago (#2s)

Past Month (#3s)

Lifetime (#1,2,or 3)

Track Gap Between Prior and current

Lifetime Problems to identify “under

reporting”

Track progress in reducing current

(past month) symptoms)

Monitor for Relapse

GAIN Short Screener Profile: Reclaiming Futures (Range based on 0/1-2/3+ Symptoms)

33% 37%48%

38%

81%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

InternalizingDisorderScreener

ExternalizingDisorderScreener

SubstanceDisorderScreener

Crime/ViolenceScreener

TotalDisorderScreener

Low

Mod.

High

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

GAIN Short Screener Number of Problems Mod/Hi in Reclaiming Futures

40%

22%

22%

9%7%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

No. ofProblems

No SR prob

1 Prob.

2 Probs.

3 Probs.

4 Probs.

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

93% endorsed one or more problems

(40% 4 or more)

Construct Validity of GSS Internalizing Disorder Screener

0%10%20%30%40%50%60%70%80%90%

100%

% Days with MHproblem

Mod/High onEmotional Problem

Scale (EPS)

Mod/High onInternal MentalDistress Scale

(IMDS)

Internalizing Disorder Screener (IDScr)

Fu

ll G

AIN

mea

sure

0 1 2 3 4 5

Source: Education Service District 113 (n=979) and King County (n=1002)

Construct Validity of GSS Externalizing Disorder Screener

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

% Days withbehavioralproblems

Mod/High onEmotional Problem

Scale (EPS)

High on BehaviorComplexity Scale

(BCS)

Externalizing Disorder Screener (EDScr)

Fu

ll G

AIN

mea

sure

0 1 2 3 4 5

Source: Education Service District 113 (n=979) and King County (n=1002)

Construct Validity of GSS Substance Disorder Screener

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

% Days of AOD use

Past Year Abuse orDependence

Past YearDependence

Substance Disorder Screener (SDScr)

Fu

ll G

AIN

mea

sure

0 1 2 3 4 5

Source: Education Service District 113 (n=979) and King County (n=1002)

Construct Validity of GSS Crime/Violence Screener

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

% Days of illegalactivities

Mod/High onIllegal Activity

Scale (IAS)

High onCrime/Violence

Scale (CVS)

Crime and Violence Screener (CVScr)

Fu

ll G

AIN

mea

sure

0 1 2 3 4 5

Source: Education Service District 113 (n=979) and King County (n=1002)

Adolescent Rates of High (2+) Scores on Mental Health (MH) or Substance Abuse (SA) Screener by Setting

in Washington State

77% 86

%

73%

75%

61%67

%

83%

62%

75%

60%

57%

40% 46

%

12%

12%

47%

37%

35%

12%

11%

0%10%20%30%40%50%60%70%80%90%

100%

Substance AbuseTreatment(n=8,213)

Student AssistancePrograms(n=8,777)

Juvenile Justice(n=2,024)

Mental HealthTreatment (10,937)

Children'sAdministration

(n=239)

Either High on Mental Health High on Substance High on Both

Source: Lucenko et al (2009). Report to the Legislature: Co-Occurring Disorders Among DSHS Clients. Olympia, WA: Department of Social and Health Services. Retrieved from http://publications.rda.dshs.wa.gov/1392/

Problems could be easily identified Comorbidity is common

Adult Rates of High (2+) Scores on Mental Health (MH) or Substance Abuse (SA) Screener

by Setting in Washington State

81%

78%

65%

64% 69

%

18%

68% 73

%

43%

44%

69%

17%

69%

51%

53%

51%

17%

4%

56%

46%

31%

31%

17%

3%

0%10%20%30%40%50%60%70%80%90%

100%

SubstanceAbuse

Treatment(n=75,208)

Eastern StateHospital(n=422)

Corrections:Community(n=2,723)

Corrections:Prison

(n=7,881)

Mental HealthTreatment(55,847)

ChildrensAdministration

(n=1,238)

Either High on Mental Health High on Substance High on Both

Source: Lucenko et al (2009). Report to the Legislature: Co-Occurring Disorders Among DSHS Clients. Olympia, WA: Department of Social and Health Services. Retrieved from http://publications.rda.dshs.wa.gov/1392/

Lower than expected rates of SA in Mental Health & Children’s

Admin

35%

12%

11%

56%

34%

15%

9%

47%

0%10%20%30%40%50%60%70%80%90%

100%

Substance AbuseTreatment (n=8,213)

Juvenile Justice(n=2,024)

Mental HealthTreatment (10,937)

Children'sAdministration

(n=239)

GAIN Short Screener Clinical Indicators

Source: Lucenko et al (2009). Report to the Legislature: Co-Occurring Disorders Among DSHS Clients. Olympia, WA: Department of Social and Health Services. Retrieved from http://publications.rda.dshs.wa.gov/1392/

Adolescent Client Validation of Hi Co-occurring from GAIN Short Screener vs Clinical Records

by Setting in Washington State

Two page measure closely approximated all found in the clinical record after the next two years

Adult Client Validation of Hi Co-occurring from GAIN Short Screener vs Clinical Records

by Setting in Washington State

17%

3%

59%

39%

22%

56%

0%

10%20%

30%40%

50%

60%70%

80%90%

100%

Substance Abuse Treatment(n=75,208)

Mental Health Treatment(55,847)

Childrens Administration(n=1,238)

GAIN Short Screener Clinical Indicators

Source: Lucenko et al (2009). Report to the Legislature: Co-Occurring Disorders Among DSHS Clients. Olympia, WA: Department of Social and Health Services. Retrieved from http://publications.rda.dshs.wa.gov/1392/

Higher rate in clinical record in Mental Health and Children’s Administration

(But that was past on “any use” vs. “abuse/dependence” and 2 years vs. past year

Other ValidationsConfirmatory Factor Analysis Dennis, Chan & Funk (2006) found that the 20 item GSS and its four subscales

were highly correlated (.84 to .94) with the full scale, had 90% sensitivity and over 90% area under the curve relative to the full GAIN; Confirmatory factors analysis also found it to be consistent with the overall model of psychopathology after allowing for age (CFI=.92; RMSEA=.06).

Substance Disorders: McDonnell and colleagues (2009) found that the 5-item GAIN SS Substance

Disorder Screener had 92% sensitivity and 85% correct classification relative to the Diagnostic Inventory Scale for Children (DISC) Predictive Scales (DPS; Lucas et al 2001) and 88% sensitivity and 88% correct classification relative to the CRAFFT (Knight et al 2001)

Internalizing Disorders: McDonnell and colleagues (2009) found that the 5-item GAIN SS Internalizing

Disorder Screener had 100% sensitivity and 75% correct classification relative to the Youth Self Report (YSR; Achenbach et al, 2001) and that the 5-item GAIN SS Externalizing Disorder Screener had 89% sensitivity and 65% correct classification to the YSR.

Riley and colleagues (2009) found that the 5-item GAIN SS’s Internalizing Disorder Screener had 92% sensitivity and 80% area under the curve relative to the Structured Clinical Interview for DSM (SCID) and was more efficient relative to 11 item Addiction Severity Index (ASI) psychiatric composite score (McLellan et al., 1992), 10 item K10 (Kessler et al., 2002) and the 87 item Psychiatric Diagnostic Screening Questionnaire (PDSQ; Zimmerman and Mattia, 2001)

GAIN Quick (GQ): Version 2

Strengths: Length (20-30min) in desired range, range of topics, efficiently categorizes, narrative reports to support screening, brief intervention, and referral to treatment

Problems: – Lacks scales or recency to support analyses or outcomes

related to “change over time”– Item response choices do not provide information about

lifetime problems important when someone has been incarcerated for more than a few weeks

– Current Personal Feedback Report focuses only on substance use and does not address the other content areas of the GAIN-Q

– Only about 60% of the items can be directly imported into the GAIN-I

GAIN Quick (GQ): Changes from Version 2 to 3:

Kept focus on screening, brief intervention and referral to treatment

Broke out sections for Crime/Violence, HIV risk, Work and School problems

Subsumed GSS and added similar screeners in other GAIN Q areas with recency response to address change and lifetime issues

Change measures for each symptom count and days items Created reasons for change items in each area to support

brief intervention, reducing number of items in substance use

Make all questions importable into full GAIN Expand narrative report to have more treatment planning

statements and to allow motivational interviewing within each area

GAIN-Quick (GQ) Version 3

Administration Time: about 25 minutes for core (varies depending on severity) and on average 25-45 minutes using full with motivational interview questions (depending on number of problem areas probed).

Training Requirements: 1 day (train the trainer) training plus certification within 1-2 months for administration certification, and 2 days of motivational intervention training plus 1-3 months for clinical certification.

Mode: Generally staff-administered on computer (can be done on paper or self-administered with proctor).

Purpose: Designed for use in targeted populations for more detailed screening, to support brief intervention or referral for further assessment or behavioral intervention.

GAIN-Quick (GQ) Scales:

– GAIN SS scales + similar scales for school, work, physical health, psychosocial stress, and HIV risks

– Additional “days” items and scale for measuring behavioral change– Recency and past 90 day measures of service utilization in each

area to aid in placement, track implementation and estimate quarterly costs to society

– Reasons for change to support motivational interviewing in each area

– Life Satisfaction Scale and interview quality documentation

Response Set: Recency (“the last time” scale), Breadth (past year symptom counts for behavior and lifetime for utilization) and Prevalence (past 90 days)

GAIN-Quick (GQ) Problem Profile (Range based on 0/1-2/3+ Symptoms)

68%

26%

58%63%52%

6%

46% 47%

32%

0%10%20%30%40%50%60%70%80%90%

100%

Schoo

l Pro

blems

Wor

k Pro

blems

Physica

l Hea

lth P

roblem

s

Problem

s with

Str

ess

Risk B

ehav

ior P

roblem

s

Inte

rnali

zing D

isord

ers

Exter

nalizin

g Diso

rder

s

Substance

Use

Pro

blems

Crime &

Viol

ence

Pro

blems

Low

Mod

High

Source: GAIN-Q Pilot (n=138)

Number of Problems

94%3%1%1%1%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

No. ofProblems

No SR prob

1 Prob.

2 Probs.

3 Probs.

4 Probs.

99% endorsed one or more problems(94% 4 or more

problems)

Source: GAIN-Q Pilot (n=138)

Distribution of Summary Indices

15% 13%31%

49%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

ProblemPrevelance

Index

QuarterlyCost to Society

Qualityof Life

LifeSatisfaction

Index

High-good

Mod

Low

Low

Mod

High-bad

Source: GAIN Q Pilot . (n=138)

Problem Prevalence Index

Percent of days of problems in each of 8 areas summed, divided by range (23 items), and multiplied by 100 to get a score from 0 to 100.

Problem Prevalence Index can be interpreted continuously where up is bad and subjectively unpleasant.

It can also be triaged to low (0-5), moderate (6-24) or high (100) based on roughly 50%, 40% and 10% of the clinical population.

Mean score here was 12.7 (10.2 Std. Dev).

Quarterly Costs to Society

The frequency of using tangible services in the 90 days before intake (e.g., health care utilization, days in detention, probation, parole, days of missed school) in each of the 8 areas valued in 2009 dollars, and summed.

Quarterly costs to society can be used continuously with up as more expensive to society.

It can also be triaged as low ($0 to $1999), moderate ($2000 to $9999) and high ($10000 or more) based on average costs of outpatient and residential treatment respectively.

The 138 clients here cost society an average of $6,118 (SD=$12,382) per person in the quarter before intake and $24,471 (SD=$49,551) in the year before intake.

Source: GAIN-Q Pilot (n=138)

Quality of Life Year (QOLY)

Triage of past year problem count in each of the 9 screeners weighted as No or Low=2, Moderate=1 and High=0; summed, divided by range 18, and multiple by 100 to get a quality of life score from 0 to 100.

Quality of Life Year measure can be interpreted continuously where up is good and subjectively pleasant.

It can also be triaged to low (0-36), moderate (37-69) or high (70 to 100) based on roughly 50%, 40% and 10% of the clinical population.

Mean score here was 39.7 (18.8 Std. Dev).

Life Satisfaction Index

Likert rating from strongly disagree (1) to strongly agree (5) in 5 areas (sexual relationship, living situation, family relationships, school/work situation, how life is going so far, general level of happiness) is summed and ranges from 6 to 30

Life Satisfaction Index can be interpreted continuously where up is good

It can also be triaged to low (6-15), moderate (16-27) or high (28-30) on roughly 50%, 40% and 10% of the clinical population

Mean score here was 19.3 (5.7 Std. Dev) and was related to other summary indices

GAIN Treatment Planning/Placement Grid

Problem Recency/Severity

None Past Current (past 90 days)*

Low-Mod | High Severity Treatm

ent H

istory**

Non

e Past C

urren

t .

1. No Problem2. Past problem Consider monitoring and relapse prevention.

3. Low/Moderate problems; Not in treatmentConsider initial or low invasive treatment.

4. Severe problems;Not in treatment Consider a more intensive treatment or intervention strategies.

0. Not LogicalCheck under- standing of problem or lying and recode.

5. No current problems; Currently in treatmentReview for step down or discharge.

6. Low/Moderate problems; Currently in treatment Review need to continue or step up.

7. Severe problems; Currently in treatmentReview need for more intensive or assertive levels.

* Current for Intoxication & Withdrawal = Past 7 days** Engagement in what ever the relevant service system is (school or work for vocational)

Treatment Planning Needs by GQ Problem Area

0% 20% 40% 60% 80% 100%

School*

Work*

Health Problems

Stress

Risk Behaviors

Internal Disorders

External Disorders

Substance Disorders

Crime & Violence*

Inconsistent No problem Past Prob Low/Mod ProbHigh Prob No Prob in Tx L/M Prob in Tx H Prob in Tx

* For school and work, in TX is defined as engaged; for Crime & violence, it is involved with CJS. Source: GAIN-Q Pilot (n=138)

Use of Motivational Interviewing by GQ Problem Area

Source: GAIN-Q Pilot (n=138)

59%

8%

67%

77%

45%

88%

85%

62%

0% 20% 40% 60% 80% 100%

School

Work

Physical Health

Stress

Risk Behaviors

Mental Health

Substance Use

Crime & Violence

GAIN Q Section

Duration Varies by Number of Problem Areas Where MI Questions Asked

0

10

20

30

40

50

60

0 1 2 3 4 5 6 7 8Number of areas where MI done

Min

utes

0%

20%

40%

60%

80%

100%

% o

f Sa

mpl

e

Minutes % of Sample

Minutes: Mean=45, sd=15

Median=4-5 Problems Areas

Source: GAIN-Q Pilot (n=138)

GAIN Initial (GI) Administration Time: Core version 60-90 minutes; Full version 110-140

minutes (depending on severity) Training Requirements: 3.5 days (train the trainer) plus recommend formal

certification program (administration certification within 3 months of training; local trainer certification within 6 months of training); Advanced clinical interpretation recommended for clinical supervisors and lead clinicians

Mode: Generally Staff Administered on Computer (can be done on paper or self administered with proctor)

Purpose: Designed to provide a standardized biopsychosocial for people presenting to a substance abuse treatment using DSM-IV for diagnosis, ASAM for placement, and needing to meet common (CARF, COA, JCAHO, insurance, CDS/TEDS, Medicaid, CSAT, NIDA) requirements for assessment, diagnosis, placement, treatment planning, accreditation, performance/outcome monitoring, economic analysis, program planning and to support referral/communications with other systems

Scales: The GI has 9 sections (access to care, substance use, physical health, risk and protective behaviors, mental health, recovery environment, legal, vocational, and staff ratings) that include 103 long (alpha over .9) and short (alpha over .7) scales, summative indices, and over 3000 created variables to support clinical decision making and evaluation. It is also modularized to support customization

Response Set: Breadth (past year symptom counts for behavior and lifetime for utilization), Recency (48 hours, 3-7 days, 1-4 weeks, 2-3 months, 4-12 months, 1+ years, never) and Prevalence (past 90 days), patient and staff ratings

Interpretation: – Items can be used individually or to create specific diagnostic or

treatment planning statements– Items can be summed into scales or indices for each behavior

problem or type of service utilization– All scales, indices and selected individual items have interpretative

cut-points to facilitate clinical interpretation and decision making

GAIN Initial (GI) (continued)

Reports: – Validity Report (VR): identifying missing/bad data and

potentially problematic areas of assessment– Individual Clinical Profile (ICP): lab report with graphical

and tabular summary with links back to the items– GAIN Recommendation and Referral Summary (GRRS):

Draft of biopsychosocial narrative for clinician to use for initial assessment summary, diagnosis, placement and treatment planning

– Personal Feedback Report (PFR): used to support Motivational Interviewing (MI) / Motivational Enhancement Therapy (MET)

– Program Profile: program level report that allows comparison of client characteristics, services received and outcomes between programs, cohorts or types of clients.

GAIN Initial (GI) (continued)

GAIN Initial Profile: Substance Problems Past Year(Range based range of clinical/logical/statistical rules)

31%19%15%

7%0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Sub.

Use

/In

duce

dP

rob.

Abu

se

Dep

ende

nce

Sub.

Pro

b.P

ast

Yea

r

Low

Mod.

High

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

GAIN Initial Profile: Substance Problems by Time(Range based range of clinical/logical/statistical rules)

39%31%

13%2%0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Sub.

Pro

b.L

ifet

ime

Sub.

Pro

b.P

ast

Yea

r

Sub.

Pro

b.P

ast

Mon

th

Wit

hdra

wal

Sx P

ast

Wee

k

Low

Mod.

High

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

GAIN Initial Profile: Motivation and Readiness(Range based range of clinical/logical/statistical rules)

0% 7%19%

32%

76%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Self

-E

ffic

acy

Tre

atm

ent

Res

ista

nce

Tre

atm

ent

Pre

ssur

e

Tre

atm

ent

Mot

ivat

ion

Pro

blem

Ori

enta

tion

Low

Mod.

High

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

GAIN Initial Profile: Crime/Violence(Range based range of clinical/logical/statistical rules)

25%33%

5% 8%

51%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Con

flic

t-T

acti

c

Pro

pert

yC

rim

e

Inte

rper

sona

lC

rim

e

Dru

g C

rim

e

Cri

me

Vio

lenc

e

Low

Mod.

High

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

GAIN Initial Profile: Environmental Risk(Range based range of clinical/logical/statistical rules)

39%

64%54%

28%

0%

10%

20%30%

40%

50%

60%

70%80%

90%

100%

Liv

ing

Env

iron

men

tR

isk

Voc

atio

nal

Env

iron

men

tR

isk

Soci

alE

nvir

onm

ent

Ris

k

Env

iron

men

tal

Ris

k

Low

Mod.

High

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

GAIN Initial Profile: Internalizing Disorders(Range based range of clinical/logical/statistical rules)

3%15%

1% 9% 9%24%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Som

atic

Dep

ress

ion

Suci

de R

isk

Anx

iety

-F

ear

Tru

ama

Inte

rnal

izin

g

Low

Mod.

High

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

GAIN Initial Profile: Externalizing Disorders(Range based range of clinical/logical/statistical rules)

20%12% 14% 20%

0%

10%20%

30%

40%50%

60%

70%

80%90%

100%

Inat

tent

iven

ess

Hyp

erac

tivi

ty-

impl

usiv

e

Con

duct

Dis

orde

r

Ext

erna

lizi

ng

Low

Mod.

High

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

GAIN Initial Profile: Personality Disorders(Range based range of clinical/logical/statistical rules)

53%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Cau

tiou

s(C

lust

er A

)

Impl

usiv

e(C

lust

er B

)

Wor

ryin

g(C

lust

er C

)

Tot

alP

erso

nali

ty

Low

Mod.

High

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

GAIN Initial Profile: General Factors / Stress(Range based range of clinical/logical/statistical rules)

26%44%

10% 12%0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Em

ploy

men

tP

rob.

S

choo

lP

rob.

Vic

tim

izat

ion

P

erso

nA

xis

IV

O

ther

Axi

sIV

Low

Mod.

High

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

GAIN Initial Profile: Other Problem Scales(Range based range of clinical/logical/statistical rules)

12%2% 4%

17%0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Hea

lth

Gam

blin

g

Soci

alSu

ppor

t

Lif

eSa

tisf

acti

on

Low

Mod.

High

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

GAIN Initial Profile: Measures of Behavior Change (Range based range of clinical/logical/statistical rules)

41%

3% 10% 14%

41%23%

3%4%0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%Su

bsta

nce

Use

Hea

lth

Em

otio

ns

Rec

over

yE

nvir

onm

ent

Ille

gal

Act

ivit

y

Scho

ol

Wor

k

Fin

anci

al

Low

Mod.

High

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

GAIN Initial Number of Problems Mod/Hi

98%0%0%1%1%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

No. ofProblems

No problems

1 Prob.

2 Probs.

3 Probs.

4 Probs.

99% endorsed one or more problems

(98% 4 or more)

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

Any Illegal Activity in the Next Six Months by Intake Severity on Crime/Violence and Substance Problem Scales

58%46%

36%53%

33%26%44%

27%20%

0%

20%

40%

60%

An

y I

leg

al

Ac

tiv

ity

(mo

nth

s1

-6)

High Mod Low LowMod

High

Crime/Violence Scale (Intake)

Substance Problem Scale

(Intake)

Source: CSAT 2008 V5 dataset Adolescents aged 12-17 with 3 and/or 6 month follow-up (N=9006)

Intake Crime/ Violence Severity

Predicts Recidivism

Intake Substance Problem Severity

Predicts Recidivism

Knowing both is a better predictor(high –high group is 5.5 times more

likely than low low)

While there is risk, most (42-80%) actually do not commit

additional crime

GAIN Treatment Planning/Placement Grid

Problem Recency/Severity

None Past Current (past 90 days)*

Low-Mod | High Severity Treatm

ent H

istory

Non

e Past C

urren

t .

1. No Problem2. Past problem Consider monitoring and relapse prevention.

3. Low/Moderate problems; Not in treatmentConsider initial or low invasive treatment.

4. Severe problems;Not in treatment Consider a more intensive treatment or intervention strategies.

0. Not LogicalCheck under- standing of problem or lying and recode.

5. No current problems; Currently in treatmentReview for step down or discharge.

6. Low/Moderate problems; Currently in treatment Review need to continue or step up.

7. Severe problems; Currently in treatmentReview need for more intensive or assertive levels.

* Current for Intoxication & Withdrawal = Past 7 days

Reclaiming Futures ASAM Placement Cells

0% 20% 40% 60% 80% 100%

B1.Intox/Withd.

B2 Biomedical

B3.Psych/Beh

B4.Readiness

B5.Rel. Pot.

B6.Environ.

Inconsistent No problem Past Prob Low/Mod ProbHigh Prob No Prob in Tx L/M Prob in Tx H Prob in Tx

Source: Reclaiming Futures Portland, OR and Santa Cruz, CA sites (n=192)

Other Common Treatment Planning Needs: Reclaiming Futures

90%

89%

87%

80%

76%

74%

73%

70%

66%

62%

61%

59%

58%

57%

56%

0%

10

%

20

%

30

%

40

%

50

%

60

%

70

%

80

%

90

%

10

0%

Continuing care

Case management

Recovery Environment Risk

Coping w/ Psychosocial Stressors

Accessing Treatment

Child Maltreatment

Disatisfaction with Environment

Behavior Control

School Problems

Anger Management

Vocational Assistance

Detox or Withdrawal

Recovery Coach

HIV risk reduction (sex)

Tobacco CessationSource: Reclaiming Futures (n=192)

75

Part 3. Highlight our current work to using actuarial estimates of outcomes to improve placement decisions

CSAT Adolescent Treatment GAIN Data from 203 level of care x site combinations

Outpatient

General Group Home

Short-Term Residential

Outpatient Continuing CareIntensive Outpatient

Long-term ResidentialModerate-Term Residential

Early InterventionOtherCorrections

Levels of Care

Source: Dennis, Funk & Hanes-Stevens, 2008

Ratings of Problem Severity (x-axis) by Treatment Utilization (y-axis) by Population Size (circle size)

12%

20%

14%

8%

14%

12%

-0.20

0.00

0.20

0.40

0.60

0.80

1.00

-0.20 0.00 0.20 0.40 0.60 0.80 1.00

Average Current Problem Severity

Ave

rage

Cur

rent

Tre

atm

ent U

tili

zati

on

.

A Low-Low

B Low- Mod

C Mod-Mod

DHi-Low

EHi-Mod

F. Hi-Hi (CC)

G. Hi-Mod(Env Sx/ PH Tx)

9%

H. Hi-Hi(Intx Sx; PH/MH Tx) 12%

Variance Explained in 10 NOMS Outcomes

\1 Past month \2 Past 90 days *All statistically Significant

26%

24%

11%

25%

15%

33%

26%

18%

14%

8%

24%

0% 5% 10% 15% 20% 25% 30% 35%

No AOD Use

No AOD related Prob.

No Health Problems

No Mental Health Prob.

No Illegal Activity

No JJ System Involve.

Living in Community

No Family Prob.

Vocationally Engaged

Social Support

Count of above

Percent of Variance Explained

Source: CSAT 2007 AT Outcome Data Set (n=11,013)

Predicted Count of Positive Outcomes by Level of Care: Cluster A Low - Low (n=1,025)

2

3

4

5

6

7

8

9

10

Outpatient Higher LOC

2

3

4

5

6

7

8

9

10

Predicted Count of Positive Outcomes by Level of Care: Cluster A Low - Low (n=1,025)

Person “A” does better in Outpatient

Person “B” does better in Higher Levels of Care

Best Level of Care*: Cluster A Low - Low (n=1,025)

Source: CSAT 2007 AT Outcome Data Set (n=11,013)

Best Level of Care*: Cluster A Low - Low (n=1,025)

99.6%

0.4%0%

20%

40%

60%

80%

100%

120%

Outpatient Higher LOC

% B

est

Pre

dic

ted O

utc

om

es

* Based on Maximum Predicted Count of Positive Outcomes

Source: CSAT 2007 AT Outcome Data Set (n=11,013)

Best Level of Care*: Cluster B Low - Mod (n=1,654)

0.4%

14.1%

75.1%

10.5%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

Outpatient IOP OPCC Residential

% B

est P

redi

cted

Out

com

es

* Based on Maximum Predicted Count of Positive Outcomes

Best Level of Care*: Cluster C Mod-Mod (n=1209)

Source: CSAT 2007 AT Outcome Data Set (n=11,013)

Best Level of Care*: Cluster C Mod-Mod (n=1209)

30.2%

7.6%

23.6%

38.6%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

Outpatient IOP OPCC Residential

% B

est

Pre

dic

ted O

utc

om

es

* Based on Maximum Predicted Count of Positive Outcomes

Source: CSAT 2007 AT Outcome Data Set (n=11,013)

Best Level of Care*: Cluster D Hi-Low (n=687)

38.3%33.8%

27.9%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

Outpatient IOP/OPCC Residential * Based on Maximum Predicted Count of Positive Outcomes

Best Level of Care*: Cluster F Hi-Hi (CC) (n=968)

Source: CSAT 2007 AT Outcome Data Set (n=11,013)

Best Level of Care*: Cluster F Hi-Hi (CC) (n=968)

81.5%

8.6%

0.0%

9.9%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

Outpatient IOP OPCC Residential

% B

est

Pre

dic

ted O

utc

om

es

* Based on Maximum Predicted Count of Positive Outcomes

Source: CSAT 2007 AT Outcome Data Set (n=11,013)

Best Level of Care*: Cluster Cluster H Hi-Hi (Intx/PH/MH) (n=1,017)

78.2%

17.2%

0.0%4.6%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

Outpatient IOP OPCC Residential

% B

est P

redi

cted

Out

com

es

* Based on Maximum Predicted Count of Positive Outcomes

Source: CSAT 2007 AT Outcome Data Set (n=11,013)

Best Level of Care*: Cluster E Hi-Mod (n=1,190)

1.1%

88.3%

10.6%

0.0%0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

Outpatient IOP OPCC Residential

% B

est P

redi

cted

Out

com

es

* Based on Maximum Predicted Count of Positive Outcomes

Best Level of Care*: Cluster G Hi-Mod (Env/PH) (n=749)

Source: CSAT 2007 AT Outcome Data Set (n=11,013)

Best Level of Care*: Cluster G Hi-Mod (Env/PH) (n=749)

94.1%

5.9%0.0%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

Outpatient IOP/OPCC Residential

* Based on Maximum Predicted Count of Positive Outcomes

Best (x) by Actual (y) Level of Care Placement

3132

797

1968

2339

0

500

1000

1500

2000

2500

3000

3500

Outpatient (n=3132)

Intensive Outpatient(n=797)

OP - ContinuingCare (n=1968)

Residential(n=2339)

Higher

Best

Lower

553/771=72%unmet need

218/224=97% to targeted

771/982=79% in need

Exploring Need, Unmet Need, & Targeting of Mental Health Services in AAFT

Size of the Problem

Extent to which services are currently being targeted

Extent to which services are not reaching those in most need

At Intake .

After 3 mon

No/Low

Need

Mod/High

Need

Total

Any Treatment 6 218 224

No Treatment 205 553 758

Total 211 771 982

Mental Health Problem (at intake) vs. Any MH Treatment by 3 months

79%

97%

72%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

% of Clients WithMod/High Need

(n=771/982)*

% w Need but No ServiceAfter 3 months

(n=553/771)

% of Services Going toThose in Need

(n=218/224)

*3+ on ASAM dimension B3 criteriaSource: 2008 CSAT AAFT Summary Analytic Dataset

Why Do We Care About Unmet Need?

If we subset to those in need, getting mental health services predicts reduced mental health problems

Both psychosocial and medication interventions are associated with reduced problems

If we subset to those NOT in need, getting mental health services does NOT predict change in mental health problems

Conversely, we also care about services being poorly targeted to those in need.

Residential Treatment need (at intake) vs. 7+ Residential days at 3 months

36%

52%

90%

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

% of Clients WithMod/High Need

(n=349/980)*

% w Need but NoService After 3 months

(n=315/349)

% of Services Going toThose in Need (n=34/66)

Opportunity to redirect

existing funds through better

targeting

Source: 2008 CSAT AAFT Summary Analytic Dataset

93

Part 4. Summarize the status of efforts to make the data available for secondary analysis and translate the software, measures and reports from English into Spanish, French, Portuguese and other languages

94

We currently pool data from Center for Substance Abuse Treatment (CSAT) grantees annual and make it available for secondary analysis:

– Requires abstract length proposal/ feasibility– Requires agreement to respect privacy and not attempt to re-identify– We will get permission from any active grantees– No cost to the end user

Over 36 scientist and evaluators have already accessed the data and about 1-2 more come get approval each month

We can also negotiate access to additional data from individual grantees and/or regional projects

Secondary Analysis

95

Status of Translations

LanguageShortScreener

Other Instruments Software Reports

English Done Done Done Done

Spanish Done Done In progress In progress

French In progress In progress In progress In progress

Portuguese Done Starting Not yet Not Yet

Japanese Done Not yet Not yet Not Yet

Hmong, Japanese, Russian, Pilipino, Punjabi, Vietnamese

Done Not yet Not yet Not Yet

96

Acknowledgments and Contact Information This presentation was supported by analytic runs provided by Chestnut Health Systems for the

Substance Abuse and Mental Health Services Administration's (SAMHSA's) Center for Substance Abuse Treatment (CSAT) under Contracts 207-98-7047, 277-00-6500, 270-2003-00006 and 270-2007-00004C using data provided by the following 152 grantees: TI11317 TI11321 TI11323 TI11324 TI11422 TI11423 TI11424 TI11432 TI11433 TI11871 TI11874 TI11888 TI11892 TI11894 TI13190TI13305 TI13308 TI13313 TI13322 TI13323 TI13344 TI13345 TI13354 TI13356 TI13601 TI14090 TI14188 TI14189 TI14196 TI14252 TI14261 TI14267 TI14271 TI14272 TI14283 TI14311 TI14315 TI14376 TI15413 TI15415 TI15421 TI15433 TI15438 TI15446 TI15447 TI15458 TI15461 TI15466 TI15467 TI15469 TI15475 TI15478 TI15479 TI15481 TI15483 TI15485 TI15486 TI15489 TI15511 TI15514 TI15524 TI15524 TI15527 TI15545 TI15562 TI15577 TI15584 TI15586 TI15670 TI15671 TI15672 TI15674 TI15677 TI15678 TI15682 TI15686 TI16386 TI16400 TI16414 TI16904 TI16928 TI16939 TI16961 TI16984 TI16992 TI17046 TI17070 TI17071 TI17334 TI17433 TI17434 TI17446 TI17475 TI17476 TI17484 TI17486 TI17490 TI17517 TI17523 TI17535 TI17547 TI17589 TI17604 TI17605 TI17638 TI17646 TI17648 TI17673 TI17702 TI17719 TI17724 TI17728 TI17742 TI17744 TI17751 TI17755 TI17761 TI17763 TI17765 TI17769 TI17775 TI17779 TI17786 TI17788 TI17812 TI17817 TI17825 TI17830 TI17831 TI17864 TI18406 TI18587 TI18671 TI18723 TI19313 TI19323 TI655374. Any opinions about this data are those of the authors and do not reflect official positions of the government or individual grantees. It is available at www.chestnut.org/li/posters. Comments or questions can be addressed to Michael Dennis, Chestnut Health Systems, 448 Wylie Drive, Normal, IL 61761. Phone 1-309-451-7801; E-mail: [email protected].

More information on the GAIN is available at www.chestnut.org/li/gain or by e-mailing [email protected] .