> FIELDS OF ACTIONMedical devices

Biocides

Veterinary

Agrochemicals

Chemicals

Food additives

Cosmetics

Pharmaceuticals

> ASSETS20 years experience

Competitive prices

Reactivity

Multidisciplinary team

Confidentiality

Registered ethics committee(n°76 by French Ministry of Research)

TOXICOLOGY - MUTAGENICITY - BIOCOMPATIBILITY1500 GLP studies per year

International Regulations (OECD, FDA, EPA, JHLWX, EC…)

GLP CONTRACT RESEARCH ORGANISATION IN VIVO AND IN VITRO STUDIES

> TOXICOLOGYEye corrosion and irritationIn vitro: OECD 438, OECD 492,HetcamIn vivo: OECD 405

Skin corrosion and irritationIn vitro: OECD 435, OECD 431,OECD 439In vivo: OECD 404

Acute oral toxicityOECD 423, OECD 420, OECD 425

Acute dermal toxicityOECD 402

Sensitization studiesAlternative and in vitro:LLNA: OECD 429, OECD 442B,OECD 442C, OECD 442D, OECD 442EIn vivo: OECD 406

Dermal absorptionIn vitro: OECD 428In vivo: OECD 427

Acute inhalation toxicityOECD 436, OECD 403

> MUTAGENICITY-GENOTOXICITYGene mutation in bacteriaOECD 471

MicronucleusOECD 487, OECD 474

Chromosome aberrationOECD 473

Mammalian Cell Gene MutationOECD 490

More services (in partnership)

Aquatic toxicity

Consulting services: Registration ofAgrochemicals, Biocides and Reach,CLP regulation (updating MSDS),risk assessment…

Companies need toxicity datas as part of there dossiers.

GLP TOXICOLOGY STUDIES

WWW.PHYCHER.COMinfo@phycher.com - Phone: +33 (0)5 5797 1680

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