Golongan Darah ABO Rhesus

7/23/2019 Golongan Darah ABO Rhesus

http://slidepdf.com/reader/full/golongan-darah-abo-rhesus 1/161

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\par}{\phpg\posx2270\pvpg\posy6980\absw9054\absh7318 \sl-414 \b \f10 \fs21 \cf0\fi720 {\b0 Pernah}{\b0 dikakukan}{\b0 percobaan}{\b0 oleh}{\b0 dokter}{\b0pribadi}{\b0 Raja}{\b0 Perancis}{\b0 Lwiss}{\b0 ke }



\par}{\phpg\posx2270\pvpg\posy6980\absw9054\absh7318 \sl-413 \b \f10 \fs21 \cf0{\b0 XIV}{\b0 memberikan}{\b0 darah}{\b0 domba}{\b0 pada}{\b0 orang}{\b0 gila}{\b0 tersebut,}{\b0 karena}{\b0 dia}{\b0 berpendapat }\par}{\phpg\posx2270\pvpg\posy6980\absw9054\absh7318 \sl-414 \b \f10 \fs21 \cf0{\b0 dan}{\b0 orang}{\b0 beranggapan}{\b0 pada}{\b0 waktu}{\b0 itu}{\b0 domba}{\b0 bersifat}{\b0 peramah.}{\b0 Tetapi}{\b0 ternyata }\par}{\phpg\posx2270\pvpg\posy6980\absw9054\absh7318 \sl-414 \b \f10 \fs21 \cf0

{\b0 mengakibatkan}{\b0 kematian,}{\b0 sehingga}{\b0 sejak}{\b0 itu}{\b0 dilarang}{\b0 untuk}{\b0 melakukan }\par}{\phpg\posx2270\pvpg\posy6980\absw9054\absh7318 \sl-413 \b \f10 \fs21 \cf0{\b0 pemindahan}{\b0 darah}{\b0 (transfusi}{\b0 darah). }\par}{\phpg\posx2270\pvpg\posy6980\absw9054\absh7318 \sl-414 \b \f10 \fs21 \cf0\fi720 {\b0 Lalu}{\b0 pada}{\b0 Tahun}{\b0 1900}{\b0 Dr.Karl}{\b0 Landsteiner}{\b0 mengumumkan}{\b0 penemuannya }\par}{\phpg\posx2270\pvpg\posy6980\absw9054\absh7318 \sl-413 \b \f10 \fs21 \cf0{\b0 tentang}{\b0 golongan}{\b0 darah}{\b0 manusia.}{\b0 Sejak}{\b0 penemuan}{\b0 inilah}{\b0 pemindahan}{\b0 darah }\par}{\phpg\posx2270\pvpg\posy6980\absw9054\absh7318 \sl-414 \b \f10 \fs21 \cf0{\b0 (transfusi)}{\b0 darah}{\b0 ini}{\b0 tidak}{\b0 lagi}{\b0 berbaha

ya,}{\b0 sudah}{\b0 dapat}{\b0 menolong}{\b0 penderita- }\par}\sect\sectd\pard\plain\pgwsxn11900\pghsxn16840{\phpg\posx0\pvpg\posy0\absw11900\absh16840 \overlay{\*\shppict {\pict\jpegblip\picw595 \pich842\picwgoal11900 \pichgoal16840\picscalex135 \picscaley135ffd8ffe000104a46494600010100000100010000ffdb00430001010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101ffdb00430101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101ffc0001108034a025303012200021101031101ffc4001f00000105010101010101000000000000000001

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0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a00ffd9}}\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \f10 \fs21 \cf0 \f10 \fs21 \cf0 penderita yang kekurangan darah. Dengan ditemukannya golongan dar

ah oleh\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 Dr.Karl Landsteiner, dapatlah dijelaskan sebab - sebab kematian yang dulu akibat\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 dari transfusi darah. Pada penyelidikannya juga dia dapat menemukan zat-zat\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 yang dapat menghalangi pembekuan darah, sehingga darah yang diambil dari\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 tubuh tidak segera membeku. Selain itu dia menemukan, bahwa dengan\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 pe

nambahan larutan glukosa ke dalam darah dapat memperpanjang hidup\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 Erythrocyt diluar tubuh manusia. Dengan penemuan, darah sudah dapat disimpan\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 sebelum ditransfusikan kedalam tubuh penderita.\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 \fi720 Pada perang dunia ke II, akibat banyaknya korban-korban yang mengalami\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 perdarahan-perdarahan juga memberi kesempatan untuk penyelidik-penyelidikan\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 sehingga pengetahuan mengenai penyimpanan darah ini dapat dilakukan secara\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 intensif, sehingga transfusi darah dapat ditunjukkan untuk pengobatan-pengobatan

\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 dan juga penelitian tentang penggunaan bagian-bagian dari darah.\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 \fi720 Juga semakin majunya ilmu pengetahuan mengenai golongan darah ini,\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 semakin banyak digunakan pada bagian-bagian lain, seperti dalam bidang\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 kriminal. Golongan darah dapat juga membantu mencari identitas seseorang,\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 seperti bercak-bercak darah yang ditemukan akibat pembunuhan dapat membantu\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 petugas kepolisian. Dalam menentukan keturunan, golongan darah ini juga dapat\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 membantu, karena golongan darah si anak akan bergantung pada golongan darah\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 kedua orang tuanya.\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 \fi720 Dalam kebanyakan pengamatan, pencampuran darah yang berasal dari 2\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 orang yang berbeda akan menyebabkan timbulnya pengendapan sel - sel darah\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 merah. Peristiwa pengendapan sel tersebut dinamai sebagai aglutinasi.\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 Pengamatan selanjutnya memperlihatkan, bahwa peristiwa ini melibatkan sel

\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 darah merah dan bagian cair dari darah, yaitu serum atau plasma.\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 \f



i720 Penemuan Golongan darah ini dilandasi oleh adanya Interaksi Antigen- \par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 Antibodi. Antibodi adalah molekul protein (immunoglobulin) yang memiliki satu\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 atau lebih tempat perlekatan (combining sites) yang disebut paratope. Antigen

\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-414 \f10 \fs21 \cf0 adalah molekul asing yang mendatangkan suatu respon spesifik\par}{\phpg\posx2270\pvpg\posy2278\absw9021\absh11044 \sl-413 \f10 \fs21 \cf0 dari limfosit. \par}\sect\sectd\pard\plain\pgwsxn11900\pghsxn16840{\phpg\posx0\pvpg\posy0\absw11900\absh16840 \overlay{\*\shppict {\pict\jpegblip\picw595 \pich842\picwgoal11900 \pichgoal16840\picscalex135 \picscaley135ffd8ffe000104a46494600010100000100010000ffdb004300010101010101010101010101010101

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10 \fs21 \cf0 Sejak tahun 1900 sampai dengan tahun 1962 telah dikenal orang dengan\par}{\phpg\posx2270\pvpg\posy2278\absw8919\absh4337 \sl-413 \f10 \fs21 \cf0 bai



k, 12 macam system golongan darah, yang penting dalam bidang transfusi \par}{\phpg\posx2270\pvpg\posy2278\absw8919\absh4337 \sl-414 \f10 \fs21 \cf0 darah dan kehamilan. Golongan dimaksud adalah system - system : ABO, MNSs,\par}{\phpg\posx2270\pvpg\posy2278\absw8919\absh4337 \sl-414 \f10 \fs21 \cf0 P,Rhesus, Lutheran, Kell, Lewis, Duffy, Kidd, Ausberger, Xg dan Doombrok.

\par}{\phpg\posx2270\pvpg\posy2278\absw8919\absh4337 \sl-413 \f10 \fs21 \cf0 Dan masih ada lagi system - system golongan darah lainnya seperti Diego, Sutter\par}{\phpg\posx2270\pvpg\posy2278\absw8919\absh4337 \sl-414 \f10 \fs21 \cf0 yang ditemukan pada beberapa ras bangsa saja dan lainnya.\par}{\phpg\posx2270\pvpg\posy2278\absw8919\absh4337 \sl-413 \f10 \fs21 \cf0 \fi720 Didalam transfusi darah hanya system ABO yang merupakan golongan\par}{\phpg\posx2270\pvpg\posy2278\absw8919\absh4337 \sl-414 \f10 \fs21 \cf0 terpenting untuk tujuan-tujuan klinis. System golongan darah lainnya dianggap\par}{\phpg\posx2270\pvpg\posy2278\absw8919\absh4337 \sl-414 \f10 \fs21 \cf0 kurang mempunyai arti klinis karena termasuk memiliki antigen-antigen

\par}{\phpg\posx2270\pvpg\posy2278\absw8919\absh4337 \sl-413 \f10 \fs21 \cf0 mengalami yang transfusi lemah, yang dan antibodynya berulangkali. Dan baru\par}{\phpg\posx2270\pvpg\posy2278\absw8919\absh4337 \sl-414 \f10 \fs21 \cf0 zat timbul antinya setelah biasanya mempunyai suhu optimum reaksi yang rendah\par}{\phpg\posx2270\pvpg\posy2278\absw8919\absh4337 \sl-413 \f10 \fs21 \cf0 ( dibawah 37° C ), sehingga tidak mempunyai arti klinis yang berarti. \par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \b \f10 \fs21 \cf0 \fi720 \b \f10 \fs21 \cf0 Pemeriksaan golongan darah ABO\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-413 \b \f10 \fs21 \cf0\fi720 {\b0 Golongan}{\b0 darah}{\b0 merupakan}{\b0 ciri}{\b0 khusus}{\b0 darah}{\b0 dari}{\b0 suatu}{\b0 individu}{\b0 karena }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-414 \b \f10 \fs21 \cf0

{\b0 adanya}{\b0 perbedaan}{\b0 jenis}{\b0 karbohidrat}{\b0 dan}{\b0 protein}{\b0 pada}{\b0 permukaan}{\b0 membran}{\b0 sel }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-413 \b \f10 \fs21 \cf0{\b0 darah}{\b0 merah.}{\b0 Golongan}{\b0 darah}{\b0 ditentukan}{\b0 oleh}{\b0 jumlah}{\b0 zat}{\b0 (kemudian}{\b0 disebut }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-413 \b \f10 \fs21 \cf0{\b0 antigen)}{\b0 yang}{\b0 terkandung}{\b0 di}{\b0 dalam}{\b0 sel}{\b0 darah}{\b0 merah}{\b0 (Fitri,}{\b0 2007). }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-413 \b \f10 \fs21 \cf0\fi720 {\b0 Secara}{\b0 umum,}{\b0 golongan}{\b0 darah}{\b0 O}{\b0 adalah}{\b0 yang}{\b0 paling}{\b0 umum}{\b0 dijumpai}{\b0 di }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-413 \b \f10 \fs21 \cf0{\b0 dunia,}{\b0 meskipun}{\b0 di}{\b0 beberapa}{\b0 negara}{\b0 seperti}{\b0 Swedia}{\b0 dan}{\b0 Norwegia,}{\b0 golongan }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-414 \b \f10 \fs21 \cf0{\b0 darah}{\b0 A}{\b0 lebih}{\b0 dominan.}{\b0 Antigen}{\b0 A}{\b0 lebih}{\b0 umum}{\b0 dijumpai}{\b0 dibanding}{\b0 antigen}{\b0 B. }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-413 \b \f10 \fs21 \cf0{\b0 Karena}{\b0 golongan}{\b0 darah}{\b0 AB}{\b0 memerlukan}{\b0 keberadaan}{\b0 dua}{\b0 antigen,}{\b0 A}{\b0 dan}{\b0 B, }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-414 \b \f10 \fs21 \cf0{\b0 golongan}{\b0 darah}{\b0 ini}{\b0 adalah}{\b0 jenis}{\b0 yang}{\b0 paling}{\b0 jarang}{\b0 dijumpai}{\b0 di}{\b0 dunia.}{\b0 (Alrasyid, }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-414 \b \f10 \fs21 \cf0{\b0 2010). }

\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-413 \b \f10 \fs21 \cf0\fi720 {\b0 Golongan}{\b0 darah}{\b0 menurut}{\b0 sistem}{\b0 A-B-O}{\b0 dapat}{\b0 diwariskan}{\b0 dari}{\b0 orang}{\b0 tua }



\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-414 \b \f10 \fs21 \cf0{\b0 kepada}{\b0 anaknya.}{\b0 Land-Steiner}{\b0 dalam}{\b0 Suryo}{\b0 (1996)}{\b0 membedakan}{\b0 darah}{\b0 manusia }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-413 \b \f10 \fs21 \cf0{\b0 kedalam}{\b0 empat}{\b0 golongan}{\b0 yaitu}{\b0 A,}{\b0 B,}{\b0AB}{\b0 dan}{\b0 O.}{\b0 Penggolongan}{\b0 darah}{\b0 ini }

\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-414 \b \f10 \fs21 \cf0

{\b0 disebabkan}{\b0 oleh}{\b0 macam}{\b0 antigen}{\b0 yang}{\b0 dikandung}{\b0 oleh}{\b0 eritrosit}{\b0 (sel}{\b0 darah}{\b0 merah). }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-414 \b \f10 \fs21 \cf0\fi720 {\b0 Sebagian}{\b0 besar}{\b0 gen}{\b0 yang}{\b0 ada}{\b0 dalam}{\b0 populasi}{\b0 sebenarnya}{\b0 hadir}{\b0 dalam}{\b0 lebih }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-413 \b \f10 \fs21 \cf0{\b0 dari}{\b0 dua}{\b0 bentuk}{\b0 alel.}{\b0 Golongan}{\b0 darah}{\b0 ABO}{\b0 pada}{\b0 manusia}{\b0 merupakan}{\b0 satu}{\b0 contoh }\par}{\phpg\posx2270\pvpg\posy7660\absw8965\absh6573 \sl-414 \b \f10 \fs21 \cf0{\b0 dari}{\b0 alel}{\b0 berganda}{\b0 dari}{\b0 sebuah}{\b0 gen}{\b0 tunggal.}{\b0 Ada}{\b0 empat}{\b0 kemungkinan}{\b0 fenotip}{\b0 untuk }\par}

\sect\sectd\pard\plain\pgwsxn11900\pghsxn16840{\phpg\posx0\pvpg\posy0\absw11900\absh16840 \overlay{\*\shppict {\pict\jpegblip\picw595 \pich842\picwgoal11900 \pichgoal16840\picscalex135 \picscaley135ffd8ffe000104a46494600010100000100010000ffdb00430001010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101ffdb00430101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101ffc0001108034a025303012200021101031101ffc4001f0000010501010101010100000000000000000102030405060708090a0bffc400b5100002010303020403050504040000017d01020300041105122131410613516107227114328191a1082342b1c11552d1f02433627282090a161718191a2526272829

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

























0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a00ffd9}}\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \f10 \fs21 \cf0 \f10 \fs21 \cf0 untuk karakter ini: Golongan darah seseorang mungkin A, B, AB atau O. Huruf-\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 hu

ruf ini menunjukkan dua karbohidrat, substansi A dan substansi B, yang \par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 mungkin ditemukan pada permukaan sel darah merah. Sel darah seseorang\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 mungkin mempunyai sebuah substansi (tipe A atau B), kedua-duanya (tipe AB),\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 atau tidak sama sekali (tipe O).\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 \fi720 Golongan darah yang berbeda yaitu A, B, AB dan O. ditentukan oleh \par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 se

pasang gen, yang diwarisi dari kedua orang tua. Setiap golongan darah dapat\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 dikenal dari zat kimia yang disebut antigen, yang terletak di permukaan sel darah\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 merah. Ketika seseorang membutuhkan transfusi darah, maka darah yang\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 disumbangkan haruslah sesuai dengan golongan darah tertentu. Kesalahan dalam\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 melakukan transfusi akan dapat menimbulkan komplikasi yang serius. (Australia\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 Red Cross, 2008).\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 \f

i720 Pemeriksaan golongan darah mempunyai berbagai manfaat dan \par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 mempersingkat waktu dalam identifikasi. Golongan darah penting untuk diketahui\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 dalam hal kepentingan transfusi, donor yang tepat serta identifikasi pada kasus\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 kedokteran forensik seperti identifikasi pada beberapa kasus kriminal (Azmielvita, \par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 2009).\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 \fi720 Kesesuaian golongan darah sangatlah penting dalam transfusi darah. Jika\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 darah donor mempunyai faktor (A atau B) yang dianggap asing oleh resipien,\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 protein spesifik yang disebut antibodi yang diproduksi oleh resipien akan \par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 mengikatkan diri pada molekul asing tersebut sehingga menyebabkan sel-sel\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 darah yang disumbangkan menggumpal. Penggumpalan ini dapat membunuh\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 resipien (Azmielvita, 2009).

\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 \fi720 Karl Landsteiner, seorang ilmuwan asal Austria yang menemukan 3 dari 4\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 go



longan darah dalam sistem ABO pada tahun 1900 dengan cara memeriksa\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 golongan darah beberapa teman sekerjanya. Percobaan sederhana inipun\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 dilakukan dengan mereaksikan sel darah merah dengan serum dari para donor.\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 Ha

silnya adalah dua macam reaksi (menjadi dasar antigen A dan B, dikenal\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 dengan golongan darah A dan B) dan satu macam tanpa reaksi (tidak memiliki\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-413 \f10 \fs21 \cf0 antigen, dikenal dengan golongan darah O). Kesimpulannya ada dua macam\par}{\phpg\posx2270\pvpg\posy2278\absw8993\absh11417 \sl-414 \f10 \fs21 \cf0 antigen A dan B di sel darah merah yang disebut golongan A dan B, atau sama \par}\sect\sectd\pard\plain\pgwsxn11900\pghsxn16840{\phpg\posx0\pvpg\posy0\absw11900\absh16840 \overlay

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0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a00ffd9



}}\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \f10 \fs21 \cf0 \f10 \fs21 \cf0 sekali tidak ada reaksi yang disebut golongan O.\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-413 \f10 \fs21 \cf0 \fi720 Kemudian Alfred Von Decastello dan Adriano Sturli yang masih kolega\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-414 \f10 \fs21 \cf0 dari Landsteiner menemukan golongan darah AB pada tahun 1901. Pada golongan\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-414 \f10 \fs21 \cf0 da

rah AB, kedua antigen A dan B ditemukan secara bersamaan pada sel darah\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-413 \f10 \fs21 \cf0 merah sedangkan pada serum tidak ditemukan antibodi. Golongan darah manusia\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-414 \f10 \fs21 \cf0 ditentukan berdasarkan jenis antigen dan antibodi yang terkandung dalam\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-413 \f10 \fs21 \cf0 darahnya, sebagai berikut:\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-243 \par\f10 \fs21 \cf0 \fi195 {\b {\f63 \u61444\'3f}}Individu dengan golongan darah A memiliki sel darah merah dengan antigen\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-243 \par\f10 \fs21 \cf0 A di permukaan membran selnya dan menghasilkan antibodi terhadap antigen B

\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-414 \f10 \fs21 \cf0 dalam serum darahnya. Sehingga, orang dengan golongan darah A-negatif hanya\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-413 \f10 \fs21 \cf0 dapat menerima darah dari orang dengan golongan darah A-negatif atau O-negatif.\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-243 \par\f10 \fs21 \cf0 \fi195 {\b {\f63 \u61444\'3f}}Individu dengan golongan darah B memiliki antigen B pada permukaan sel\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-243 \par\f10 \fs21 \cf0 darah merahnya dan menghasilkan antibodi terhadap antigen A dalam serum\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-413 \f10 \fs21 \cf0 darahnya. Sehingga, orang dengan golongan darah B-negatif hanya dapat

\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-413 \f10 \fs21 \cf0 menerima darah dari orang dengan dolongan darah B-negatif atau O-negatif .\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-243 \par\f10 \fs21 \cf0 \fi195 {\b {\f63 \u61444\'3f}}Individu dengan golongan darah AB memilikisel darah merah dengan\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-244 \par\f10 \fs21 \cf0 antigen A dan B serta tidak menghasilkan antibodi terhadap antigen A maupun B. \par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-413 \f10 \fs21 \cf0 Sehingga, orang dengan golongan darah AB-positif dapat menerima darah dari\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-413 \f10 \fs21 \cf0 orang dengan golongan darah ABO apapun dan disebut resipien universal.\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-414 \f10 \fs21 \cf0 Namun, orang dengan golongan darah AB-positif tidak dapat mendonorkan darah\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-413 \f10 \fs21 \cf0 kecuali pada sesama AB-positif.\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-243 \par\f10 \fs21 \cf0 \fi195 {\b {\f63 \u61444\'3f}}Individu dengan golongan darah O memilikisel darah tanpa antigen, tapi\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-242 \par\f10 \fs21 \cf0 memproduksi antibodi terhadap antigen A dan B. Sehingga, orang dengan \par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-414 \f10 \fs21 \cf0 golongan darah O-negatif dapat mendonorkan darahnya kepada orang dengan\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-413 \f10 \fs21 \cf0 go

longan darah ABO apapun dan disebut donor universal. Namun, orang dengan\par}{\phpg\posx2270\pvpg\posy2278\absw8973\absh10076 \sl-414 \f10 \fs21 \cf0 golongan darah O-negatif hanya dapat menerima darah dari sesama O-negatif. \par



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{\phpg\posx4970\pvpg\posy2748\absw2276\absh1632 \f10 \fs21 \cf0 \fi490 \f10 \fs21 \cf0 Sel darah merah\par}{\phpg\posx4970\pvpg\posy2748\absw2276\absh1632 \sl-387 \f10 \fs21 \cf0 Ant



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}{\phpg\posx7616\pvpg\posy2748\absw1966\absh1632 \f10 \fs21 \cf0 \fi921 \f10 \fs21 \cf0 Plasma\par}{\phpg\posx7616\pvpg\posy2748\absw1966\absh1632 \sl-387 \f10 \fs21 \cf0 Antibodi B\par}{\phpg\posx7616\pvpg\posy2748\absw1966\absh1632 \sl-385 \f10 \fs21 \cf0 Antibodi A\par}{\phpg\posx7616\pvpg\posy2748\absw1966\absh1632 \sl-388 \f10 \fs21 \cf0 Tidak ada antibodi\par}{\phpg\posx7616\pvpg\posy2748\absw1966\absh1632 \sl-385 \f10 \fs21 \cf0 Antibodi A & B \par}

{\phpg\posx2270\pvpg\posy5042\absw8900\absh1729 \f10 \fs21 \cf0 \fi720 \f10 \fs21 \cf0 Untuk menentukan golongan darah diperlukan suatu serum penguji yang\par}{\phpg\posx2270\pvpg\posy5042\absw8900\absh1729 \sl-414 \f10 \fs21 \cf0 disebut tes serum yang terdiri dari tes serum A dan tes serum B. Darah yang akan\par}{\phpg\posx2270\pvpg\posy5042\absw8900\absh1729 \sl-414 \f10 \fs21 \cf0 kita periksa dimasukkan kedalam suatu tabung yang berisi 2cc gram fisiologis lalu\par}{\phpg\posx2270\pvpg\posy5042\absw8900\absh1729 \sl-413 \f10 \fs21 \cf0 dikocok. Darah tersebut ditaruh di atas object glass kemudian diteteskan tes serum\par}{\phpg\posx2270\pvpg\posy5042\absw8900\absh1729 \sl-414 \f10 \fs21 \cf0 A dan tes serum B. \par}{\phpg\posx4724\pvpg\posy11666\absw3299\absh239 \b \f10 \fs21 \cf0 \b \f10 \fs21 \cf0 Gambar 1{\b0 :}{\b0 Sistem}{\b0 darah}{\b0 ABO }\par

}{\phpg\posx2270\pvpg\posy12511\absw8348\absh2235 \b \f10 \fs21 \cf0 \b \f10 \fs21 \cf0 {\f63 \u61444\'3f}{\b0 Jika}{\b0 darah}{\b0 di}{\b0 A}{\b0 menggumpal,}{\b0 sedangkan}{\b0 di}{\b0 B}{\b0 tidak}{\b0 maka}{\b0 termasuk}{\b0 golongan }\par}{\phpg\posx2270\pvpg\posy12511\absw8348\absh2235 \sl-280 \par\b \f10 \fs21\cf0 {\b0 darah}{\b0 A }\par}{\phpg\posx2270\pvpg\posy12511\absw8348\absh2235 \sl-242 \par\b \f10 \fs21\cf0 {\f63 \u61444\'3f}{\b0 Jika}{\b0 darah}{\b0 di}{\b0 A}{\b0 tidak}{\b0menggumpal}{\b0 sedangkan}{\b0 di}{\b0 B}{\b0 menggumpal}{\b0 maka }\par}{\phpg\posx2270\pvpg\posy12511\absw8348\absh2235 \sl-279 \par\b \f10 \fs21\cf0 {\b0 termasuk}{\b0 golongan}{\b0 darah}{\b0 B }\par}{\phpg\posx2270\pvpg\posy12511\absw8348\absh2235 \sl-242 \par\b \f10 \fs21\cf0 {\f63 \u61444\'3f}{\b0 Jika}{\b0 darah}{\b0 di}{\b0 A}{\b0 dan}{\b0 B}{\b0 menggumpal}{\b0 maka}{\b0 termasuk}{\b0 golongan}{\b0 darah}{\b0 AB }\par}\sect\sectd\pard\plain\pgwsxn11900\pghsxn16840{\phpg\posx0\pvpg\posy0\absw11900\absh16840 \overlay{\*\shppict {\pict\jpegblip\picw595 \pich842\picwgoal11900 \pichgoal16840\picscalex135 \picscaley135ffd8ffe000104a46494600010100000100010000ffdb00430001010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101010101

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f0 Tabel 2{\b0 :}{\b0 Pengamatan}{\b0 aglutinasi}{\b0 dalam}{\b0 penggolongan}{\b0 darah}{\b0 ABO }\par}{\phpg\posx2790\pvpg\posy3380\absw945\absh1632 \f10 \fs21 \cf0 \f10 \fs21 \cf0 Kit anti A\par}{\phpg\posx2790\pvpg\posy3380\absw945\absh1632 \sl-385 \f10 \fs21 \cf0 \fi326 (+)\par}{\phpg\posx2790\pvpg\posy3380\absw945\absh1632 \sl-387 \f10 \fs21 \cf0 \fi351 (-)\par}{\phpg\posx2790\pvpg\posy3380\absw945\absh1632 \sl-386 \f10 \fs21 \cf0 \fi326 (+)\par}{\phpg\posx2790\pvpg\posy3380\absw945\absh1632 \sl-387 \f10 \fs21 \cf0 \fi3

51 (-) \par}{\phpg\posx4774\pvpg\posy3380\absw959\absh1632 \f10 \fs21 \cf0 \f10 \fs21 \cf0 Kit anti B\par}{\phpg\posx4774\pvpg\posy3380\absw959\absh1632 \sl-385 \f10 \fs21 \cf0 \fi352 (-)\par}{\phpg\posx4774\pvpg\posy3380\absw959\absh1632 \sl-387 \f10 \fs21 \cf0 \fi326 (+)\par}{\phpg\posx4774\pvpg\posy3380\absw959\absh1632 \sl-386 \f10 \fs21 \cf0 \fi326 (+)\par}{\phpg\posx4774\pvpg\posy3380\absw959\absh1632 \sl-387 \f10 \fs21 \cf0 \fi352 (-) \par}

{\phpg\posx6584\pvpg\posy3380\absw1292\absh1632 \f10 \fs21 \cf0 \f10 \fs21 \cf0Kit anti A&B\par}{\phpg\posx6584\pvpg\posy3380\absw1292\absh1632 \sl-385 \f10 \fs21 \cf0 \fi500 (+)\par}{\phpg\posx6584\pvpg\posy3380\absw1292\absh1632 \sl-387 \f10 \fs21 \cf0 \fi500 (+)\par}{\phpg\posx6584\pvpg\posy3380\absw1292\absh1632 \sl-386 \f10 \fs21 \cf0 \fi500 (+)\par}{\phpg\posx6584\pvpg\posy3380\absw1292\absh1632 \sl-387 \f10 \fs21 \cf0 \fi526 (-) \par}{\phpg\posx8446\pvpg\posy3380\absw1725\absh1632 \f10 \fs21 \cf0 \f10 \fs21 \cf0Golongan darah\par}{\phpg\posx8446\pvpg\posy3380\absw1725\absh1632 \sl-385 \f10 \fs21 \cf0 \fi681 A\par}{\phpg\posx8446\pvpg\posy3380\absw1725\absh1632 \sl-387 \f10 \fs21 \cf0 \fi690 B\par}{\phpg\posx8446\pvpg\posy3380\absw1725\absh1632 \sl-386 \f10 \fs21 \cf0 \fi601 AB\par}{\phpg\posx8446\pvpg\posy3380\absw1725\absh1632 \sl-387 \f10 \fs21 \cf0 \fi681 O \par}{\phpg\posx2270\pvpg\posy5260\absw8390\absh239 \i \f10 \fs21 \cf0 \i \f10 \fs21\cf0 Dari penuntun praktikum imunologi Sekolah Tinggi Ilmu Farmasi Riau 1;2012 \par

}{\phpg\posx3916\pvpg\posy10228\absw5247\absh239 \b \f10 \fs21 \cf0 \b \f10 \fs21 \cf0 Gambar 2 :{\b0 Pengamatan}{\b0 pada}{\b0 pemberian}{\b0 serum }\par



}{\phpg\posx2270\pvpg\posy11056\absw9018\absh3592 \f10 \fs21 \cf0 \fi720 \f10 \fs21 \cf0 Transfusi darah adalah proses menyalurkan darah atau produk berbasis\par}{\phpg\posx2270\pvpg\posy11056\absw9018\absh3592 \sl-414 \f10 \fs21 \cf0 darah dari satu orang ke sistem peredaran orang lainnya. Transfusi darah

\par}{\phpg\posx2270\pvpg\posy11056\absw9018\absh3592 \sl-413 \f10 \fs21 \cf0 berhubungan dengan kondisi medis seperti kehilangan darah dalam jumlah besar\par}{\phpg\posx2270\pvpg\posy11056\absw9018\absh3592 \sl-414 \f10 \fs21 \cf0 disebabkan trauma, operasi, syok dan tidak berfungsinya organ pembentuk sel\par}{\phpg\posx2270\pvpg\posy11056\absw9018\absh3592 \sl-413 \f10 \fs21 \cf0 darah merah.\par}{\phpg\posx2270\pvpg\posy11056\absw9018\absh3592 \sl-414 \f10 \fs21 \cf0 \fi720 Dalam transfusi darah, kecocokan antara darah donor (penyumbang) dan\par}{\phpg\posx2270\pvpg\posy11056\absw9018\absh3592 \sl-414 \f10 \fs21 \cf0 resipien (penerima) adalah sangat penting. Darah donor dan resipien harus sesuai\par}{\phpg\posx2270\pvpg\posy11056\absw9018\absh3592 \sl-413 \f10 \fs21 \cf0 go

longannya berdasarkan sistem ABO dan Rhesus faktor. Transfusi darah dari \par}{\phpg\posx2270\pvpg\posy11056\absw9018\absh3592 \sl-414 \f10 \fs21 \cf0 golongan yang tidak kompatibel dapat menyebabkan reaksi transfusi imunologis\par}{\phpg\posx2270\pvpg\posy11056\absw9018\absh3592 \sl-413 \f10 \fs21 \cf0 yang berakibat anemia hemolisis, gagal ginjal, syok, dan kematian. Hemolisis \par}\sect\sectd\pard\plain\pgwsxn11900\pghsxn16840{\phpg\posx0\pvpg\posy0\absw11900\absh16840 \overlay{\*\shppict {\pict\jpegblip\picw595 \pich842\picwgoal11900 \pichgoal16840

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}}\par}{\phpg\posx2270\pvpg\posy2278\absw8998\absh2102 \f10 \fs21 \cf0 \f10 \fs21 \cf0 adalah penguraian sel darah merah dimana hemoglobin akan terpisah dari eritrosit.\par}{\phpg\posx2270\pvpg\posy2278\absw8998\absh2102 \sl-413 \f10 \fs21 \cf0 \fi720 Pemilik rhesus negatif tidak boleh ditransfusi dengan darah rhesus positif.\par}{\phpg\posx2270\pvpg\posy2278\absw8998\absh2102 \sl-414 \f10 \fs21 \cf0 Jika dua jenis golongan darah ini saling bertemu, dipastikan akan terjadi perang.\par}{\phpg\posx2270\pvpg\posy2278\absw8998\absh2102 \sl-414 \f10 \fs21 \cf0 Sistem pertahanan tubuh resipien (penerima donor) akan menganggap rhesus dari\par}{\phpg\posx2270\pvpg\posy2278\absw8998\absh2102 \sl-413 \f10 \fs21 \cf0 donor itu sebagai benda asing yang perlu dilawan. Di dunia, pemilik darah rhesus\par}{\phpg\posx2270\pvpg\posy2278\absw8998\absh2102 \sl-414 \f10 \fs21 \cf0 negatif termasuk minoritas. \par}{\phpg\posx2270\pvpg\posy5176\absw3992\absh910 \b \f10 \fs21 \cf0 \b \f10 \fs21\cf0 Tabel 3{\b0 :}{\b0 Kecocokan}{\b0 golongan}{\b0 darah }\par}{\phpg\posx2270\pvpg\posy5176\absw3992\absh910 \sl-235 \par\b \f10 \fs21 \cf0 \fi320 {\b0 Golongan }\par}{\phpg\posx2270\pvpg\posy5176\absw3992\absh910 \sl-275 \b \f10 \fs21 \cf0 \fi118 {\b0 darah}{\b0 resipien }\par}{\phpg\posx2830\pvpg\posy6310\absw548\absh2328 \f10 \fs21 \cf0 \f10 \fs21 \cf0 AB+\par}{\phpg\posx2830\pvpg\posy6310\absw548\absh2328 \sl-385 \f10 \fs21 \cf0 \fi28 AB-

\par}{\phpg\posx2830\pvpg\posy6310\absw548\absh2328 \sl-387 \f10 \fs21 \cf0 \fi80 A+\par}{\phpg\posx2830\pvpg\posy6310\absw548\absh2328 \sl-386 \f10 \fs21 \cf0 \fi1



08 A-\par}{\phpg\posx2830\pvpg\posy6310\absw548\absh2328 \sl-388 \f10 \fs21 \cf0 \fi86 B+\par}{\phpg\posx2830\pvpg\posy6310\absw548\absh2328 \sl-385 \f10 \fs21 \cf0 \fi80 O+\par}{\phpg\posx2830\pvpg\posy6310\absw548\absh2328 \sl-388 \f10 \fs21 \cf0 \fi108 O- \par

}{\phpg\posx5794\pvpg\posy5784\absw2791\absh712 \f10 \fs21 \cf0 \fi642 \f10 \fs21 \cf0 Donor harus\par}{\phpg\posx5794\pvpg\posy5784\absw2791\absh712 \sl-263 \par\f10 \fs21 \cf0Golongan darah manapun \par}{\phpg\posx6084\pvpg\posy6696\absw386\absh1632 \f10 \fs21 \cf0 \fi28 \f10 \fs21\cf0 A-\par}{\phpg\posx6084\pvpg\posy6696\absw386\absh1632 \sl-387 \f10 \fs21 \cf0 O+\par}{\phpg\posx6084\pvpg\posy6696\absw386\absh1632 \sl-386 \f10 \fs21 \cf0 A+\par}{\phpg\posx6084\pvpg\posy6696\absw386\absh1632 \sl-388 \f10 \fs21 \cf0 O+\par}{\phpg\posx6084\pvpg\posy6696\absw386\absh1632 \sl-385 \f10 \fs21 \cf0 O+ \

par}{\phpg\posx7706\pvpg\posy6696\absw298\absh239 \f10 \fs21 \cf0 \f10 \fs21 \cf0 B- \par}{\phpg\posx4524\pvpg\posy6696\absw316\absh1981 \f10 \fs21 \cf0 \f10 \fs21 \cf0 O-\par}{\phpg\posx4524\pvpg\posy6696\absw316\absh1981 \sl-387 \f10 \fs21 \cf0 O-\par}{\phpg\posx4524\pvpg\posy6696\absw316\absh1981 \sl-386 \f10 \fs21 \cf0 O-\par}{\phpg\posx4524\pvpg\posy6696\absw316\absh1981 \sl-388 \f10 \fs21 \cf0 O-\par}{\phpg\posx4524\pvpg\posy6696\absw316\absh1981 \sl-385 \f10 \fs21 \cf0 O-\par}{\phpg\posx4524\pvpg\posy6696\absw316\absh1981 \sl-388 \f10 \fs21 \cf0 O- \par

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i427 A+B \par}{\phpg\posx7790\pvpg\posy10676\absw1816\absh239 \f10 \fs21 \cf0 \f10 \fs21 \cf0Aman ditransfusi \par}{\phpg\posx7232\pvpg\posy11062\absw1249\absh1632 \f10 \fs21 \cf0 \fi153 \f10 \fs21 \cf0 Resepien\par}{\phpg\posx7232\pvpg\posy11062\absw1249\absh1632 \sl-388 \f10 \fs21 \cf0 \fi287 A, AB\par}{\phpg\posx7232\pvpg\posy11062\absw1249\absh1632 \sl-385 \f10 \fs21 \cf0 \fi293 B, AB\par}{\phpg\posx7232\pvpg\posy11062\absw1249\absh1632 \sl-387 \f10 \fs21 \cf0 \fi427 AB\par}{\phpg\posx7232\pvpg\posy11062\absw1249\absh1632 \sl-386 \f10 \fs21 \cf0 A, B, AB, O \par}{\phpg\posx8820\pvpg\posy11062\absw1231\absh1632 \f10 \fs21 \cf0 \fi287 \f10 \fs21 \cf0 Donor\par}{\phpg\posx8820\pvpg\posy11062\absw1231\absh1632 \sl-388 \f10 \fs21 \cf0 \fi360 A, O\par}{\phpg\posx8820\pvpg\posy11062\absw1231\absh1632 \sl-385 \f10 \fs21 \cf0 \fi367 B, O\par}{\phpg\posx8820\pvpg\posy11062\absw1231\absh1632 \sl-387 \f10 \fs21 \cf0 A, B, AB, O\par}{\phpg\posx8820\pvpg\posy11062\absw1231\absh1632 \sl-386 \f10 \fs21 \cf0 \f

i507 O \par}{\phpg\posx2270\pvpg\posy12942\absw8629\absh611 \i \f10 \fs21 \cf0 \i \f10 \fs21



\cf0 Dari laporan praktikum anatomi fisiologi manusia, golongan darah FMIPA\par}{\phpg\posx2270\pvpg\posy12942\absw8629\absh611 \sl-414 \i \f10 \fs21 \cf0Universitas Negeri Jakarta. 2011. \par}\sect\sectd\pard\plain\pgwsxn11900\pghsxn16840

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4500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145001451450014514500145145007fffd9}}\par}{\phpg\posx2630\pvpg\posy2324\absw165\absh215 \f40 \fs21 \cf0 \f40 \fs21\cf0 - \par}{\phpg\posx2630\pvpg\posy3588\absw165\absh215 \f40 \fs21 \cf0 \f40 \fs21 \cf0 -\par}{\phpg\posx2630\pvpg\posy4440\absw165\absh215 \f40 \fs21 \cf0 \f40 \fs21 \cf0 -\par}{\phpg\posx2990\pvpg\posy2302\absw8114\absh2516 \f10 \fs21 \cf0 \f10 \fs21 \cf0tusuk dengan lanset dengan satu kali tusukkan, tetesan pertama dibuang\par}{\phpg\posx2990\pvpg\posy2302\absw8114\absh2516 \sl-414 \f10 \fs21 \cf0 dan tetesan selanjutnya diteteskan pada 3 objek glass, masing-masing satu\par}{\phpg\posx2990\pvpg\posy2302\absw8114\absh2516 \sl-414 \f10 \fs21 \cf0 tet

es\par}{\phpg\posx2990\pvpg\posy2302\absw8114\absh2516 \sl-217 \par\f10 \fs21 \cf0 teteskan di atas tetesan darah pada objek glass pertama kit anti A, onjek





\par}{\phpg\posx2326\pvpg\posy12580\absw1641\absh2105 \sl-385 \f10 \fs21 \cf0 Riki Erisman\par}{\phpg\posx2326\pvpg\posy12580\absw1641\absh2105 \sl-388 \f10 \fs21 \cf0 Devi Hasanti\par}{\phpg\posx2326\pvpg\posy12580\absw1641\absh2105 \sl-385 \f10 \fs21 \cf0 Eka Lisnasari\par}{\phpg\posx2326\pvpg\posy12580\absw1641\absh2105 \sl-387 \f10 \fs21 \cf0 Fi

vy Yuniarty S \par}{\phpg\posx4006\pvpg\posy12580\absw2129\absh239 \f10 \fs21 \cf0 \f10 \fs21 \cf0Kit anti A Kit anti B \par}{\phpg\posx4388\pvpg\posy13106\absw376\absh1632 \f10 \fs21 \cf0 \fi28 \f10 \fs21 \cf0 (-)\par}{\phpg\posx4388\pvpg\posy13106\absw376\absh1632 \sl-385 \f10 \fs21 \cf0 (+) \par}{\phpg\posx4388\pvpg\posy13106\absw376\absh1632 \sl-388 \f10 \fs21 \cf0 \fi28 (-)\par}{\phpg\posx4388\pvpg\posy13106\absw376\absh1632 \sl-385 \f10 \fs21 \cf0 \fi

28 (-)\par}{\phpg\posx4388\pvpg\posy13106\absw376\absh1632 \sl-387 \f10 \fs21 \cf0 \fi28 (-) \par}{\phpg\posx5544\pvpg\posy13106\absw376\absh1632 \f10 \fs21 \cf0 \fi26 \f10 \fs21 \cf0 (-)\par}{\phpg\posx5544\pvpg\posy13106\absw376\absh1632 \sl-385 \f10 \fs21 \cf0 (+) \par}{\phpg\posx5544\pvpg\posy13106\absw376\absh1632 \sl-388 \f10 \fs21 \cf0 (+) \par}{\phpg\posx5544\pvpg\posy13106\absw376\absh1632 \sl-385 \f10 \fs21 \cf0 \fi26 (-)\par}{\phpg\posx5544\pvpg\posy13106\absw376\absh1632 \sl-387 \f10 \fs21 \cf0 \fi

26 (-) \par}{\phpg\posx6440\pvpg\posy12442\absw807\absh2229 \f10 \fs21 \cf0 \f10 \fs21 \cf0Kit Anti\par}{\phpg\posx6440\pvpg\posy12442\absw807\absh2229 \sl-276 \f10 \fs21 \cf0 \fi223 AB\par}{\phpg\posx6440\pvpg\posy12442\absw807\absh2229 \sl-387 \f10 \fs21 \cf0 \fi270 (-)\par}{\phpg\posx6440\pvpg\posy12442\absw807\absh2229 \sl-385 \f10 \fs21 \cf0 \fi243 (+)\par}{\phpg\posx6440\pvpg\posy12442\absw807\absh2229 \sl-388 \f10 \fs21 \cf0 \fi243 (+)\par}{\phpg\posx6440\pvpg\posy12442\absw807\absh2229 \sl-385 \f10 \fs21 \cf0 \fi270 (-)\par}{\phpg\posx6440\pvpg\posy12442\absw807\absh2229 \sl-387 \f10 \fs21 \cf0 \fi270 (-) \par}{\phpg\posx7476\pvpg\posy12580\absw974\absh2105 \f10 \fs21 \cf0 \f10 \fs21 \cf0Kit anti D\par}{\phpg\posx7476\pvpg\posy12580\absw974\absh2105 \sl-262 \par\f10 \fs21 \cf0 \fi370 (+)\par}{\phpg\posx7476\pvpg\posy12580\absw974\absh2105 \sl-385 \f10 \fs21 \cf0 \fi370 (+)\par}{\phpg\posx7476\pvpg\posy12580\absw974\absh2105 \sl-388 \f10 \fs21 \cf0 \fi370 (+)

\par}{\phpg\posx7476\pvpg\posy12580\absw974\absh2105 \sl-385 \f10 \fs21 \cf0 \fi370 (+)\par}{\phpg\posx7476\pvpg\posy12580\absw974\absh2105 \sl-387 \f10 \fs21 \cf0 \fi



370 (+) \par}{\phpg\posx8682\pvpg\posy12442\absw1111\absh2229 \f10 \fs21 \cf0 \f10 \fs21 \cf0 Golongan\par}{\phpg\posx8682\pvpg\posy12442\absw1111\absh2229 \sl-276 \f10 \fs21 \cf0 \fi180 Darah\par}{\phpg\posx8682\pvpg\posy12442\absw1111\absh2229 \sl-387 \f10 \fs21 \cf0 \f

i387 O\par}{\phpg\posx8682\pvpg\posy12442\absw1111\absh2229 \sl-385 \f10 \fs21 \cf0 \fi307 AB\par}{\phpg\posx8682\pvpg\posy12442\absw1111\absh2229 \sl-388 \f10 \fs21 \cf0 \fi393 B\par}{\phpg\posx8682\pvpg\posy12442\absw1111\absh2229 \sl-385 \f10 \fs21 \cf0 \fi387 O\par}{\phpg\posx8682\pvpg\posy12442\absw1111\absh2229 \sl-387 \f10 \fs21 \cf0 \fi387 O \par}{\phpg\posx9780\pvpg\posy12580\absw351\absh2105 \f10 \fs21 \cf0 \f10 \fs21 \cf0Rh

\par}{\phpg\posx9780\pvpg\posy12580\absw351\absh2105 \sl-262 \par\f10 \fs21 \cf0 \fi117 +\par}{\phpg\posx9780\pvpg\posy12580\absw351\absh2105 \sl-385 \f10 \fs21 \cf0 \fi117 +\par}{\phpg\posx9780\pvpg\posy12580\absw351\absh2105 \sl-388 \f10 \fs21 \cf0 \fi117 +\par}{\phpg\posx9780\pvpg\posy12580\absw351\absh2105 \sl-385 \f10 \fs21 \cf0 \fi117 +\par}{\phpg\posx9780\pvpg\posy12580\absw351\absh2105 \sl-387 \f10 \fs21 \cf0 \fi117 + \par}\sect\sectd\pard\plain\pgwsxn11900\pghsxn16840

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a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28

























0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a00ffd9}}\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \f10 \fs21 \cf0 \f10 \fs21 \cf0 menyebabkan infeksi. Selanjutnya, darah yang keluar diteteskan pada kedua sisi\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-413 \f10 \fs21 \cf0 kaca objek, sesegera mungkin sebelum darah membeku. Masing-masing tetesan

\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-414 \f10 \fs21 \cf0 darah diberi serum anti A dan anti B.\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-414 \f10 \fs21 \cf0 \fi720 Golongan darah sistem ABO dibagi berdasarkan struktur antigen \par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-413 \f10 \fs21 \cf0 permukaan eritrosit, yang disebut juga sebagai aglutinogen.\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-414 \f10 \fs21 \cf0 \fi720 Penggolongan darah pada praktikum ini dilakukan dengan melihat apakah\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-413 \f10 \fs21 \cf0 terjadi penggumpalan setelah mencampurkan darah dengan masing-masing\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-414 \f10 \fs21 \cf0 antiserum A dan B. Reaksi penggumpalan dapat terjadi akibat antigen dara

h\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-414 \f10 \fs21 \cf0 Opraktikan terhadap serum anti-A dan anti-B yang berasal dari masing-masing\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-413 \f10 \fs21 \cf0 darah B dan A. Serum anti-A yang diteteskan menandakan bahwa darah yang diuji\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-414 \f10 \fs21 \cf0 tersebut diberikan antigen A dari golongan darah B. Sedangkan serum anti-B yang\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-413 \f10 \fs21 \cf0 diteteskan merupakan antigen B dari golongan darah A. Jika pengumpalan darah\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-413 \f10 \fs21 \cf0 ketika ditetesi serum anti-A, maka darah tersebut memiliki anti-B pada darahnya.\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-413 \f10 \fs21 \cf0 Sedangkan jika penggumpalan terjadi akibat ditetesi serum anti-B, maka darah\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-413 \f10 \fs21 \cf0 tersebut memiliki anti-B pada darahnya.\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-414 \f10 \fs21 \cf0 \fi720 Pada darah praktikan Devi Hasanti, terjadi reaksi penggumpalan setelah\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-413 \f10 \fs21 \cf0 diberikan serum anti-B. Hal ini karena darah Devi Hasanti memiliki anti-A\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-413 \f10 \fs21 \cf0 (antibodi A), namun tidak memiliki anti-B karena ketika diteteskan serum anti-A,\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-413 \f10 \fs21 \cf0 darahnya tidak menggumpal. Maka golongan darah Devi Hasanti adalah B karena\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-413 \f10 \fs21 \cf0 go

longan darah B memiliki anti-A (plasma antibodi/ aglutinin A ) dan antigen B\par}{\phpg\posx2270\pvpg\posy2278\absw8916\absh11417 \sl-414 \f10 \fs21 \cf0 (aglutinogen B) pada darahnya. Pada darah praktikan Riki Erisman, terjadi




























Documents

Golongan Darah ABO Rhesus