Graduate Program in Biomedical Engineering · Worcester Polytechnic Institute 4 Sample Program of Study for Instrumentation/Sensors • BME: – BME523 Biomedical Instrumentation

Graduate Program in

Biomedical Engineering

Ki Chon, PhDChair

Glenn Gaudette, PhDGraduate Program Director

Advisors

• BME core faculty

• For PhD & MS students

– Thesis/dissertation advisor will become

your department advisor

Worcester Polytechnic Institute

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General Course Requirements• MS

– BME 6 credits

– Life Sciences 6 credits

– Math 6 credits

– Electives 6 credits

– Thesis 6 credits

• ME– BME 12 credits


– Math 6 credits


• PhD– BME 12 credits


– Math 6 credits


– Lab Rotations 6 credits

– Responsible Conduct of Science 1 credit

– Thesis 30 credits


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Sample Program of Study for

Instrumentation/Sensors • BME:

– BME523 Biomedical Instrumentation

– BME532: Medical Device Regulation

– BME581 Medical Imaging Systems

– BME4011 Biomedical Signal Processing

– DR or Thesis credit

– BME591 Graduate Seminar (Fall and Spring)

• Life Science Requirements:– BME562 Laboratory Animal Surgery

– BME560 Physiology for Engineers

– BME595C Cell & Molecular Biology for Engineers

• Math Requirements:– MA501 Engineering Mathematics

– MA511 Applied Statistics for Engineers and Scientists

– MA546 Design & Analysis of Experiments

• Others:– ECE503 Digital Signal Processing

– ECE4703 Real-Time Digital Signal Processing

• Other Electives:– MIS576 Project Management


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Biomedical Imaging• BME:

– BME581 Medical Imaging Systems

– BME582 Principles of In Vivo Nuclear Magnetic Resonance Imaging

– BME 4201 Biomedical Imaging






– BME595X Cell & Molecular Biology for Engineers


– MA 511 Applied Statistics for Engineers and Scientists (1st choice)

– MA 540 Probability and Mathematical Statistics I

– MA 546 Design and Analysis of Experiments

• Others:– ECE 502 Analysis of Probabilistic Signals and Systems

– ECE 503 Digital Signal Processing

– ECE 545 Digital Image Processing



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Biomechanics/Biomaterials• BME:

– BME550 Tissue Engineering

– BME552 Tissue Mechanics

– BME554 Composites with Biomedical and Materials Applications

– BME558 Biofluids and Biotransport


– BME595C: Cardiovascular Engineering & Regeneration

– BME4504 Biomechanics










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Tissue Engineering• BME:

– BME550 Tissue Engineering

– BME554 Composites with Biomedical and Materials Applications


– BME595C: Cardiovascular Engineering & Regeneration

– BME 4828 Biomaterial - Tissue Interactions









Graduate School

• Work more independently than

undergraduate

• Produce your own work

• GPA > 2.75 to make satisfactory

progress

• GPA > or = 3.0 to graduate

• No more than 2 C grades


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Getting Around Gateway

• Access to Gateway is restricted – if

you need access see your advisor

• Visitor Parking lot on side of

Gateway

• Shuttle is available/SNAP after hours

• Jean Siequist is Graduate

Administrative Assistant (4th floor of

Gateway)


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Kristen Billiar

Glenn Gaudette

Magnetic Resonance

Imaging

Bio-Instrumentation/

Biosensors

Tissue Engineering/

Biomaterials

K Helmer, 2005

Faculty

Christopher Sotak

Ki Chon

Don Granquist-Fraser

Yitzhak Mendelson

Ray Page

George Pins

Marsha Rolle

Tissue Engineering/

Biomechanics


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Adjunct/Associated Faculty

• Mechanical Engineering– Holly Ault

– Allen Hoffman

– Brian Savilonis

– Satya Shivkumar

– John Sullivan

• Electrical Engineering– Edward Clancy

– Fred Looft

– Peder Pederson

• Mathematical Sciences– Dalin Tang

• Chemical Engineering– Terri Camesano

• UMass Medical School– Matt Gounis

– Mitch Albert

– Mike King

– Ray Dunn


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Prof Chris Sotak

Biomedical ImagingDevelopment of magnetic

resonance imaging (MRI) methods

for evaluating acute stroke and its

response to therapy.

Development of MRI endpoints for

evaluating therapeutic efficacy in

pre-clinical models of cancer.

Development of novel MRI contrast

agents for targeted visualization of

specific biological processes.


Ki Chon, Ph.D.Ph.D., Univ. of Southern California, Biomedical Engineering

Post-doc, Harvard-MIT

Industry, Otis Elevator

Funding: NIH, Navy, Juvenile Diabetes Research Foundation

Research Interests: Development of noninvasive, predictive and diagnostic

health monitoring devices

– Atrial Fibrillation Detection

– Hypovolemia detection using pulse oximeter

– Diabetic

cardiac

neuropathy

detection

kDa

43

34

26

Actin

Synapto: C57 Akita

Prof. Don Granquist-FraserResearch Interests: BI3 →

Bio-Instrumentation, Imaging &Interface

Remote & Non-invasive Biometry

& Signal Acquisition

Novel Imaging Systems & Detectors

Phase Space Signal Source Separation

PROCESSEDRETURN

MICROWAVETRANSCEIVER

HORNANTENNAS

22 GHz REMOTE ECG SYSTEM


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Biomedical Engineering (1983) Ph.D. Case Western Reserve University.

Electrical Engineering (1976) M.Sc. State University of NY, Buffalo, NY.

Electrical Engineering (1975) B.Sc. State University of NY, Buffalo, NY.

EDUCATION:

Prof. Yitzhak Mendelson

TEACHING:

BME 3011 Bioinstrumentation and Biosensors

(Basic properties of biosensors and biomedical instrumentation)

BME 4011 Biomedical Signal Analysis

(Properties and processing of biomedical signals)

BME 4023 & BME 523 Biomedical Instrumentation Design(Design of biomedical instrumentation)

WEARABLE WIRELESS TELESENSORSRESEARCH:• Embedded Microcontrollers-Based Devices

• Physiological Signal Processing


Raymond Page, Ph.D.Ph.D. Virginia Tech, Chemical Engineering

Industry: PPL Therapeutics, Advanced Cell Technology, Cellthera

Funding: DSO/DARPA

Research Interests: Tissue regeneration using autologous cell therapy, cell phenotype

manipulation, delivery systems and functional monitoring.

– Cell de-differentiation

– Biomaterial micro-thread cell delivery systems

– In vivo transplantation/ functional monitoring

Surface Signaling

Biomaterial Scaffolds

0

2

4

6

8

10

12

14

16

0.5

00

0.7

55

1.0

10

1.2

65

1.5

20

1.7

75

2.0

30

2.2

85

2.5

40

2.7

95

3.0

50

3.3

05

3.5

60

3.8

15

4.0

70

4.3

25

4.5

80

4.8

35

5.0

90

5.3

45

5.6

00

5.8

55

6.1

10

6.3

65

Teta

nic

Fo

rce

(g)

Time (s)

Intermittent Stimulation

Non-Injured Injured


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Prof. George Pins

Research Interests: Biomimetic Scaffolds to

Enhance Tissue Regeneration

– Microtextured basal lamina analogs

– ECM-cell interactions

– Biopolymer microthreads

(Downing, JBMR, 72A: 47)

(Bush, JBMR, 80A: 47, Bush, JBMR, in press)

(Cornwell, JBMR, 82A: 104)


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Prof Marsha Rolle

Cell-based vascular tissue engineering

• Generate living vascular tissue

models with cell self-assembly

• Mechanical and physiological testing

of engineered vascular tissue

• Molecular and genetic control of cell

phenotype and ECM synthesis

2 mm


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Prof Kris Billiar

Tissue Mechanics and Mechanobiology


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– Induction of native cardiac myocyte proliferation

– Turning adult stem cells into cardiac myocytes

– Using biological scaffolds to deliver cells to infarcted heart tissue

Prof. Glenn Gaudette

•Research Interest – Cardiac Regeneration

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Documents

Graduate Program in Biomedical Engineering · Worcester Polytechnic Institute 4 Sample Program of Study for Instrumentation/Sensors • BME: – BME523 Biomedical Instrumentation