HAAD Poison & Drug Information Center ANTIDOTE CHARTAntidote
Black widow spider antiserum Atropine sulfateIndications Black
widow spider envenomations Alpha-2 agonists, antimyesthenic agents,
bradyarrhythmia-producing agents, cholinergic agonists,
muscarine-containing mushrooms, nerve agents, organophosphate and
carbamate insecticides food-borne botulism, wound, or interstinal
colonization in children or adults( not recommended for infant
botulism) Medications causing neuroleptic malignant syndrome Lead,
zinc salts poisoningBotulinum AntitoxinBromocriptine mesylate
Calcium disodium EDTA Calcium gluconate gel Calcium gluconate
INJHydrofluoric acid skin exposure Calcium channel blockers,
fluoride salts, hyperkalemia (not digoxin-induced), hypermagnesemia
Cyanide antidote kit Cyanide poisoining Cyproheptadine Serotonin
syndrome Dantrolene sodium Malignant hyperpyrexia or muscular
rigidity Deferoxamine mesylate Iron poisoning Diazepam Digoxin
immune Fab Chloroquine and related antimalarial drugs Cardiac
glycoside-containing plant ,digitoxin, digoxin Dimercaprol (BAL)
Arsenic, copper, gold, lead, lewisite, mercury Diphenhydramine HCL
Drug-induced extrapyramidal symptoms Ethanol Ethylene glycol,
methanol Flumazenil Benzodiazepines poisoning Folinic acid
Methanol, methotrexate, trimetrexate, (Leucovorin Calcium)
pyrimethamine, trimethoprim Fomepizole Ethylene glycol,
methanolGlucagon Beta blockers, calcium channel blockers HAAD-PDIC
2008-2009 Page 1HAAD Poison & Drug Information Center ANTIDOTE
CHARTInsulin (Reglular Insulin) L-CarnitineBeta blockers, Calcium
channel blockersValproic acid (hyperammonemia, encephalopathy,
liver failure) Methylene blue Methemoglobin N-Acetylcysteine
Acetaminophen, carbon tetrachloride, other hepatotoxins Naloxone
Opioids,alpha-2 agonists, imidazoline decongestants Octreotide
acetate Sulfonylurea hypoglycemic agents Phentolamine mesylate
Catecholamine extravasation, intradigital epinephrine injection
Physostigmine Anticholinergic alkaloid-containing plants,
salicylate antihistamines, atropine and other anticholinergic,
intrathecal baclofen Phytonadione (vitamin Coumarin and Indandione
derivatives, long-acting K1) anticoagulant rodenticides ,warfarin
Potassium iodide Prevents thyroid uptake of radioactive iodine
tablet Pralidoxime chloride Organophosphate poisning Protamine
sulfate Heparin, Low-Molecular -Weight heparin (LMWH) Prussian blue
Radioactive cesium (Cs-137), radioactive thallium (Tl-201), and
non-radioactive thallium Pyrdoxine Isoniazide, Adjunct to therapy
for ethylene glycol intoxication. Scorpion Anti-serum Scorpion
Sting Snake Antivenom Snakes bites Sodium bicarbonate Chlorine gas,
Hyperkalemia, Serum Alkalinization, Urine Alkalinization: Thiamine
Ethanol, Ethylene glycolExpert advice regarding use of antidotes is
available from the PDIC Call us at800 424Adapted From Olson, KR
(Ed): Poisoning & Drug Overdose. 5th Edition. Note: List is not
all-inclusive but reflects agents used more exclusively as
antidotes orantidotal agents used infrequentlyHAAD-PDIC
2008-2009Page 2
