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Harikanth 1 , Sanjeev Kumar 2 , Amod Kumar 2 , Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: [email protected] 2 Central Scientific Instruments Organisation Sector 30 C, Chandigarh 3 CBME, IIT Delhi, New Delhi National Conference on Emerging Medical Instrumentation, 2010

Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: [email protected] 2 Central Scientific

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Page 1: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

Harikanth 1, Sanjeev Kumar2, Amod Kumar2, Sneh Anand3

1Vellore Institute of Technology, VelloreE mail: [email protected]

2Central Scientific Instruments OrganisationSector 30 C, Chandigarh

3CBME, IIT Delhi, New Delhi

National Conference on Emerging Medical Instrumentation, 2010

Page 2: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

OVERVIEW

Introduction Design of electrical stimulator Recording procedure Results Future scope Conclusion References

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Page 3: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

INTRODUCTION Electroencephalography Evoked Potentials

Auditory Visual Somatosensory

Types of stimulations

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Page 4: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

Electrical

Electrical

Cold Pressure

Cold Pressure

Mechanical

Mechanical

Chemical

Chemical

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Types of Stimulations

ThermalThermal

National Conference on Emerging Medical Instrumentation, 2010

Page 5: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

Electrical Stimulator

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Controlling factors Pulse widthBurst Rate of pulse

Page 6: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

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Page 7: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

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RECORDING PROCEDURE

National Conference on Emerging Medical Instrumentation, 2010

Page 8: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

CONTD…

EEG cap was connected

Disposable electrodes were connected on the wrist region for applying electrical stimulation

EEG Data was recorded using Labchart software

Stimulations were applied at different time durations

Variations of frequency and amplitude in EEG signals were observed

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Page 9: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

RESULTS

Frequency of Beta wave was found to be increased during stimulation

Amplitude of Theta wave was found to be reduced after applying stimulation

During continuous electrical stimulation, the complexity of the signal was found to be increased

Frequency and amplitude were varying randomly during the stimulation.

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Page 10: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

10National Conference on Emerging Medical Instrumentation, 2010

Normal Continuous Stimulation

Page 11: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

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EEG responses for every 3sec stimulations at P3, C3, P4 and C4 locations

Page 12: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

FUTURE SCOPE

Can be used for the study of Hypnosis effects for balanced anesthesia monitoring

Painful stimulations can be applied for further research by increasing the power of output current

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Page 13: Harikanth 1, Sanjeev Kumar 2, Amod Kumar 2, Sneh Anand 3 1 Vellore Institute of Technology, Vellore E mail: mr.harikanth@gmail.com 2 Central Scientific

CONCLUSION

Electrical stimulator was designed

EEG signals were observed at different rates of stimulations

Significant variations in Beta and theta waves were observed at every recorded location

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REFERENCES Karbowski K. Hans Berger (1873-1941), J. Neurol., Vol 249 (8), 2002, pp 1130-1131.Gloor P. Hans Berger and the discovery of the electroencephalogram,

Electroencephalography and clinical neurophysiology, Vol 28, 1969, pp 1-36.Khandpur. Hand book of biomedical instrumentation, 2nd Edition, Tata McGraw Hill, New

Delhi.Towle VL, Bolaños J, Suarez D, Tan K, Grzeszczuk R, Levin DN, Cakmur R, Frank SA, Spire

JP. The spatial location of EEG electrodes: locating the best-fitting sphere relative to cortical anatomy, Electroencephalogr Clin Neurophysiol., Vol 86 (1), 1993, pp 1-6.

Regan D. Electrical responses evoked from the human brain, Scientific American, Vol 241, 1979, pp 134-46.

Addy R.O, Dinner D.S, Luders H, Lesser R.P, Morris H.H, Wyllie E. The effects of sleep on median nerve short latency somatosensory evoked potentials, Electroencephalogr. Clin. Neurophysiol, Vol 74, 1989, pp 105-111. 

Burak, Guc lu. Low-cost computer-controlled current stimulator for the student laboratory. Adv Physiol. Educ., Vol. 31, 2007, pp. 223-231.

Xiaohong Wang, Koji Inui, Yunhai Qiu, Minoru Hoshiyama, Tuan Diep Tran Ryusuke, Kakigi. Effects of sleep on pain-related somatosensory evoked potentials in humans, Neuroscience Research, Vol. 45, 2003, pp 53-57.

http://www.beteredingen.nl/downloads/eeg_electrodes_10-20.pdfhttp://en.wikipedia.org/wiki/Electroencephalographyhttp://en.wikipedia.org/wiki/Evoked_potential

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