Healthy Outcomes 2009

HealthPartners Research Foundation:Improving health and health care through discovery and translation

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Dear Friends:

In 2009, HPRF researchers, in collaboration with research partners across the country and around the world, worked on more than 200 studies on health behaviors, chronic disease, neurology and Alzheimer’s disease, and oral health and dental care. They disseminated the results of their research by publishing 199 articles, books and book chapters and by giving 124 paper and poster presentations at national and international conferences.

All of this research is possible only through our agency funding and donations from individuals. We thank everyone who contributed in 2009. Together, we are making a difference.

Sincerely,

Andrew F. Nelson, MPHExecutive Director

Andrew F. Nelson, MPH

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As researcher closes lab, not a dry eye in the house

As balm for both the eye and the soul, tears undeniably serve many essential functions. Few of us, though, regard them as anything more than a sign of distress. And even fewer make a distinguished career out of making more of them.

J. Daniel Nelson, M.D., an ophthalmology clinician-researcher with HealthPartners Research Foundation, has elevated the status of tears from humble saline secretions to significant physiological indicators during

his nearly 30 years in clinical research into conditions such as dry eye. “I was most interested in taking a clinical problem into the lab and seeing if I could do something about it,” he says.

Dr. Nelson and William Frey, Ph.D., whose previous studies of eliciting human tears with sad movies or Bermuda onions led to the finding that emotional and irritant tears were chemically different, discovered that there were also differences in tear composition between men’s and women’s tears. This eventually led to the discovery that human tears contain the hormone prolactin. That finding paved the way for important research on tear secretion and its relation to dry eye and its many variants.

A foundation of ophthalmologic discovery

Dr. Nelson is closing his research lab at Regions Hospital, St. Paul, on Jan. 1, 2011, because funding for the tools and technology to further his research is no longer available. But he will continue in his role as associate medical director of specialty care for HealthPartners Medical Group and, just as important, ophthalmologic researchers around the world will continue to build on his discoveries.

HealthPartners Research Foundation Executive Director Andy Nelson said that Dr. Nelson has been essential to the foundation’s overall evolution and development of research, from serving on the board in the initial

J.Daniel Nelson, MD

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merger that created HealthPartners to becoming a leader in his discipline. “We celebrate his accomplishments and look forward to his continued guidance and leadership,” Andy Nelson said. “Without his role, we would not have the capability to provide innovations that we now witness within HealthPartners.”

A lifetime of contributions to research and patients

Dr. Nelson, who grew up near Duluth, Minn. and was an Eagle Scout, published his first, and some say most defining, research paper as a resident at the University of Minnesota, where he had earned his medical degree. His 1982 description of a technique called impression cytology, a non-invasive alternative to biopsy or harvest cells for microscopic study, in Survey of Ophthalmology paved the way for easier, cheaper diagnosis of dry eye.

Although he originally planned to be a general surgeon, Nelson decided that specialty wouldn’t afford him the opportunities he wanted to take care of

patients throughout their lifespan. “You really haven’t taken care of a patient until you’ve taken care of them for life,” says Nelson, who speaks fondly of his lifelong patients, including one young lady who first came to him as a teenager.

“She wanted to be able to open her eyes to (learn to drive), then she wanted to look good for her wedding,” he says. “I’ve taken care of her for 30 years.”

Plus, Nelson says, he appreciates the ability to be able to just look at an eye to make a diagnosis rather than rely on any other senses or tests. “I tend to be visually oriented,” says Nelson. “I don’t have to listen to anything or do an X-ray to know what is going on.”

Bringing tears to our eyes

His research on dry eye led to consulting work on the development of artificial tears to lubricate and soothe this common condition. He was

“I was most interested in taking a clinical problem into the lab and seeing if I could do something about it.”

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involved in early evaluation of BionTears, an artificial tears solution made by Alcon, and clinical trials of Restasis, a formulation of cyclosporine A for the treatment of dry eye conditions such as Sjögren’s syndrome.

Dr. Nelson also promoted the use of topical steroids for dry eye before it was widely accepted, because he knew they worked; the later discovery that dry eye is an inflammatory process explained why they worked.

Many of his discoveries, Nelson says, came along a decade too soon, before the technology had been developed to take his findings to the application stage. Thus, much of his research was more fully developed in other people’s labs.

New technology led scientists to important revelations in the last few decades such as the creation of preservative-free artificial tears, which are critical in the treatment of dry eye because people with that condition don’t produce enough tears to dilute preservatives to a non-toxic level. Another milestone, according to Dr. Nelson, was the pinpointing of hypersensitivity to the preservative thimiserol in soft contact lens solutions as the culprit behind extreme irritation in some lens wearers in the 1980s.

While most of Dr. Nelson’s research focused on external eye diseases, he also delved into perfecting techniques for longer-term storage of cadaver corneas for transplantation, tested the role of antibiotics in corneal healing, and grew nerve cells and corneal cells together to assess their effects on each other.

“The eye represents so many different avenues for research,” he says.

An eye on the future

Dr. Nelson, 59, lives in Wyoming, Minn. with his wife, Carol. The couple has three grown children, two boys and a girl. He says HealthPartners Research Foundation has given him unparalleled access to other researchers and resources; he emphasizes that he’ll continue to collaborate with others in clinical research, because collaboration is key to discovery. “No one person can know everything anymore,” he says. “You need other people’s perspectives.”

Dr. Nelson will speak at HealthPartners Research Foundation’s 2010 Celebration of Research on June 16 at the 8170 Building in Bloomington. His topic? “Sex and Tears.” Nothing dry about that.

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Dance of discovery

In 1991, when a position opened up at in the Group Health Research for a scientist who would serve in a support role for physician researchers, Andy Nelson called in Cheri Rolnick. Rolnick, who was working in AIDS research at the University of Minnesota, had previously worked for Group Health as a project manager on asthma studies. “I told Andy that I also wanted to focus on my own career research interests,”

she says. “He said, ‘that’s fine, just don’t say that in your interviews’.”

Fast forward nearly 20 years, as Rolnick transitions from her position as Associate Director of the Research to 30 percent time. Not only did she do her own research on women’s health and cancer, but she helped nurture a world-class research organization that grew beyond expectations.

“Watching us grow beyond our own circle has allowed me to do things far beyond what I ever thought I’d do,” she says. “We built from nothing, and now we are a strong and legitimate force in our community and nationally.”

Steps to success

Rolnick earned her master’s degree in education administration, a masters of public health in epidemiology, and a PhD in social administration and pharmacy at the University of Minnesota. Although Rolnick’s research has focused on women’s health (eg, breast, cervical and colorectal cancer screenings, pregnancy and menopause), her innate curiosity led her to collaborate on research on issues such as circumcision, chronic obstructive pulmonary disease, rotator cuff injuries and smoking cessation. “I worked on far more topic areas than I thought I would have done when I started,” she says.

She counts her linkages with physicians and her national collaborations among her biggest accomplishments at HPRF. “I’m most proud of the ability to collaborate with people with national expertise, and I think the Cancer Research Network epitomized that.” Funded by the National Cancer Institute, the HMO Cancer Research Network is an organization of

Cheri Rolnick, PhD

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research programs, enrolled populations and data systems from 14 health maintenance organizations across the country.

In 2004, she received the HealthPartners Medical Group’s Excellence in Research Award. Prior to her award, it was given exclusively to physicians. Drs. Howard Stang and Jim Mickman, who nominated her, roasted her at the award ceremony, listing her numerous accomplishments and asking “Does this woman ever sleep?”

Another highlight was the opportunity to represent women’s health on national committees such as the American Association of Health Plans Women’s Health Task Force, a role in which she led a study identifying health plans with exemplary work on issues such as domestic abuse, birth outcomes, midlife and pregnancy.

Internally, she served as project officer, overseeing the Discovery and Partnership grant programs. “Sometimes I had to be a pitbull,” according to her own characterization in identifying gaps in the investments and the outcomes. Her tenacity led to a formal quality-assessment system to evaluate whether the internal grants achieved what they had set out to do.

Through it all, she danced. Rolnick and her husband, who both grew up in Motown (otherwise known as Detroit), began ballroom dancing in the mid 1990s when they signed up with a group of competitive dancers at what was then Northwest Health Club in Minneapolis. They took private lessons, and competed for about 5 years, repeatedly making the championship round of the National Amateur Ballroom Competitions. Now they dance three or four nights a week, doing exhibition dancing at places like malls and nursing homes. “I always tell people, ‘I work, I dance, I wash my hair’,” she says. “So if I could live at a slightly slower pace, if I could read a little more…”

“We built from nothing, and now we are a strong and legitimate force in our community and nationally.”

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Choreographing the future

Cheri will leave her full-time position at HPRF at the end of the year, staying on at about 30%. Someone else will get her corner office with the great view of Minneapolis-St. Paul International Airport, but she said she’s excited to watch other researchers blossom in the roles she has transitioned to them. Thom Flottemesch has assumed her leadership role in the Cancer Research Network, Pam Pawloski continues to develop her drug-focused work, Nancy Sherwood has taken the lead role in the National Children’s Study, and Louise Anderson will take over as internal grant project officer.

In addition to finishing her current studies at HPRF, she’ll continue in her role as chair of the steering committee of the Minnesota Cancer Alliance, and when her 2-year term expires in 2012, she’ll assume the role of Membership Committee Chair. In September, she’ll join her husband, Art Rolnick, who will be newly retired from the Federal Reserve Bank, in an advisory role at the Early Childhood Research Institute on Measuring Growth and Development at the University of Minnesota. The couple hopes to spend more time dancing and with their two sons and 2½-year-old granddaughter. “I’ve loved this,” Rolnick says of HPRF. “I’ll miss this, I’ll miss the people, but I’m ready to open some new doors.”

Look for her own take on 20 years of HPRF at the Celebration of Research on June 16, where she’ll present “Dancing with the Stars.” “My job and my dancing have filled my heart,” she says. “I would prefer to end this with a full heart than by blowing my nose.”

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Internal grant program: partnership and discovery grants

Partnership and Discovery Grants fund research that benefits patient care, education and research. These $25,000 grants are funded by donations to HPRF from the annual Sharing At Work employee fundraiser and matches from HealthPartners and awarded to any HealthPartners employee with a worthy research proposal. In 2009, HPRF awarded seven Discovery Grants

and three Partnership Grants.

Discovery grants

Ʌ Allocate funds for small, cutting-edge studies, pilot projects, and promising new investigators

Ʌ Support research in areas such as feasibility studies that test our capacity for intervention or the development of measurement tools

Ʌ Address clinical or organizational concerns

Ʌ Have promise for future external funding

Ʌ Support organizational and clinical learning to improve patient care or enhance our ability to conduct meaningful research

Ʌ 2009 Discovery Grants:ɖɖ Kenneth Adams: “Natural Language Processing (NLP)

Infrastructure Development Pilot”ɖɖ Cheri Rolnick: “Enhancing the Ability of HPRF to Conduct Cancer

Research: Linking With the Minnesota Cancer Surveillance System (MCSS)”

ɖɖ Won Chung: “Pilot Study on the Training of EMS Provider and RNs on the Use of Version 4 of the Emergency Severity Index (ESI)”

ɖɖ Autumn Erwin: “Examining the Feasibility of Sepsis Diagnosis in the Pre-Hospital Environment”

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ɖɖ Jessie Nelson: “Emergency Medicine Evaluation of Video Laryngoscopes in Simulation (EMESIS)”

ɖɖ Sandeep Bahadur: “Prevalence of Motility Disorders in Eosinophilic Esophagitis and the Response to Medical Therapy”

ɖɖ James Nordin: “Autism Prevalence in Somali and Other Immigrant Children”

Partnership grants

Ʌ Allocate funds for improving clinical practice through research

Ʌ Involve collaboration between researchers and practitioners

Ʌ Focus primarily on facilitating the evaluation of innovations and interventions at HealthPartners, HealthPartners Medical and Dental Group, and Regions Hospital

Ʌ 2009 Partnership Grantsɖɖ William Rush: “Validation and Development of Logistics for the

Administration of the Short Form of the ‘Oral Health Impact Profile’ (OHIP)”

ɖɖ David Dries: “Predictors of Successful Weaning From Mechanical Ventilation”

ɖɖ Maribet McCarty: “Predictors of Readmission to Hospital”

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HPRF study: EMR clinical decision support improves diabetes control

Electronic medical record (EMR)-based diabetes clinical decision support significantly improves glucose control and some aspects of blood pressure (BP) control in adults with type 2 diabetes, according to a landmark study by HPRF researchers Patrick O’Connor, JoAnn Sperl-Hillen, William Rush, Gerald Amundson, Stephen Asche and Heidi Ekstrom.

The study, “Impact of Electronic Medical Record (EMR) Clinical Decision Support on Diabetes Care: A Randomized Trial,” was conducted in collaboration with researchers at the University of Minnesota’s Carlson School of Management, Minneapolis, and the University of California at San Diego.

The study set out to assess the effects of an EMR-based diabetes clinical decision support system on control of glycated hemoglobin (A1c), BP, and low-density lipoprotein-cholesterol (LDL) in adults with diabetes. For 18 months, 11 Minnesota clinics with 41 primary care physicians (PCPs) and 2,556 diabetes patients were randomly assigned to receive either 1) an EMR-based clinical decision support system designed to improve care for diabetes patients above their A1c, BP, or LDL goal at any office visit or 2) No intervention.

The intervention-group PCPs used the EMR-based decision support system at 62.6% of all office visits with adults with diabetes. Over the study period, glucose, BP, and lipid control improved a great deal in all HealthPartners Medical Group (HPMG) clinics. However, diabetes patients in clinics with EMR decision support had significantly better A1c and better BP control (in some aspects) than similar patients in clinics without EMR clinical decision support. Among intervention-group PCPs, 94% were satisfied or very satisfied with the intervention, and moderate use persisted for more than a year after withdrawal of feedback and incentives to encourage use. These results underscore the potential of HPMG EMR technology to improve patients’ health. The decision support system is now being updated and rolled out to all HPMG clinics.

Based on the encouraging results of this study, the research team is now developing EMR-based clinical decision support systems that (a) prioritize all open treatment options on the basis of magnitude of benefit to the patients,

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Analyze this: HPRF informatics growing to support larger organizational role

Data doesn’t mean much if you can’t access and manipulate it. The HealthPartners Research Foundation’s Research Informatics and Information Services (RIIS) department makes clinical and laboratory study data and statistics usable and meaningful for researchers while ensuring data privacy and security. At 17 analysts and growing, this team has assumed an increasingly important role in research over the years with the burgeoning of healthcare informatics systems such as electronic medical records.

Rich Paskach, who joined HPRF as the director of RIIS in January, changed the name of the former Programming and

Analysis area to RIIS to reflect the expanded scope of its services. At the same time, he reorganized the department to improve efficiency and clarify roles and responsibilities. Paskach, who had just spent a year at Medica after 18 years in Health Informatics for HealthPartners, says the department has several large, ambitious projects as well as the many more routine study-related requests staffed by three smaller teams:

Back row: from left: Rich Paskach, Andy Rudge, Lucas Ovans, Alex Kravchik, Brita Hedblom, Jerry Amundson

Middle: Deepa Appana, Nargis Anwar, Beth Molitor, Olga Godlevsky, Nichole Schneider

Front: Amy Butani, Karen Niedenfuer, Teri Defor, Mary Becker, Ann Hanson

(continued on page 14)

and (b) elicit patient preferences for treatment options. This new work is being conducted under a new grant from the National Institutes of Health, HL102144.

The project was funded by National Institute of Diabetes, Digestive, and Kidney Diseases (NIDDK) Grant # R01 DK068314.

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Timeline

AAHRPP, Association for the Accreditation of Human Research Protection Programs; CREF, Clinical Research and Education Fund; HPRF, HealthPartners Research Foundation; IRB, Institutional Review Board; MERF, Medical Education and Research Foundation.

1983

Group Health, Inc. creates CREF

1995

IRBs of St. Paul Ramsey Hospital and HealthPartners merge

1985

Ramsey Clinic created, MERF renamed Ramsey Foundation

1998

Ramsey Hospital Foundation and Group Health Foundation merger creates HPRF

1988-1989

Board of Group Health creates Group Health Foundation

1999

New mission statement: “To advance scientific knowledge through research to improve the health of our members and the community”

1966

MERF established to promote education and research at St. Paul Ramsey Hospital

1994

Group Health Foundation helps found HMO Research Network

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AAHRPP, Association for the Accreditation of Human Research Protection Programs; CREF, Clinical Research and Education Fund; HPRF, HealthPartners Research Foundation; IRB, Institutional Review Board; MERF, Medical Education and Research Foundation.

1990

Group Health Foundation incorporates as 501c3 entity

1992

Group Health and MedCenters merge to form HealthPartners

2008

New mission statement: “To discover and accelerate the use of knowledge to improve the health and health care of our members, patients and the community”

1993

HPRF publishes first Healthy Outcomes annual report

2009

AAHRPP accredits HPRF Human Subjects Protection Program

1988-1989

Board of Group Health creates Group Health Foundation

1999

New mission statement: “To advance scientific knowledge through research to improve the health of our members and the community”

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Applications Development: The fastest-growing area, led by Senior Research Web Developer Deepa Appana, focuses on Web-based applications (eg, decision-support tools) and the HPRF Web site.

Data Systems and Architecture: This area boasts a team led by Lead Applications Analyst Jerry Amundson that focuses on development of research tools in the Epic electronic medical record system, internal data structures and the HPRF Data Mart. The latter is a long-term goal that will help increase productivity by allowing easier, faster access to data pertinent to HPRF research, Paskach says.

Virtual Data Warehouse (VDW) Architecture and Operations: The VDW is also a long-term effort to facilitate collaboration with other research organizations by allowing the pooling and manipulation of common data elements; because the organizations’ systems are already joined, there is no need to join them on the fly when specific queries are needed. This team consists of three programmer analysts and is headed by Senior Programmer Analyst Amy Butani.

Research Informatics: Led by Manager of Research Informatics Teri Defor, this team has two leads with specific areas of focus. Applications Analyst Beth Molitor is the primary contact for Technology and Systems Development, and Applications Analyst Ann Hanson is the lead for Proposal Development Support and Project Review. Hanson works with researchers on the front end to coordinate applicable preparatory work, time and resource estimates and feasibility assessments. She also guides them to the appropriate team leads to discuss programmer assignment options.

Throughout a project, the assigned lead analyst meets directly with researchers to provide data and analysis, as well as coordinates with Hanson, who brings together appropriate specialized resources to provide input in coding development, review and quality control; Appana (if unanticipated application work is needed); and Molitor (if additional hardware, software and server space are needed).

Paskach plans to emphasize customer service aspects of RIIS positions and to build a more rigorous quality-assurance program. In addition, he encourages team members to become subject matter experts (SMEs) so they can become the go-to person when questions arise in specific areas.

(continued from page 11)

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The HMO research network and the sentinel collaborative

HPRF is a member of the HMO Research Network (HMORN), a collaborative of 16 research centers affiliated with integrated health care systems. Foundation and HMORN research investigators have worked on federally funded projects such as the HMO Cancer Research Network, The Vaccine Safety Datalink, the Center for Education and Research in Therapeutics, the Coordinated Clinical Studies Network, the Cardiovascular Research Network, the DEcIDE Network, and Sentinel.

The Mini-Sentinel is a collaborative involving six of the HMORN Center for Education and Research on Therapeutics (CERT) sites, including HPRF, joined as a single organization in collaboration with 19 other national centers and organizations under the direction of Dr. Richard Platt at Harvard Pilgrim Health Care in response to an RFP published by the U.S. Food and Drug Administration to develop the Sentinel Initiative. The Sentinel Initiative is the outcome of a 2008 publication titled The Sentinel Initiative: National Strategy for Monitoring Medical Product Safety. The specific goals of the Mini-Sentinel project are:

Ʌ Funding a coordinating center with direct access to automated health care data systems

Ʌ Providing a laboratory for developing and evaluating scientific methodologies that might later be used in a fully-operational Sentinel Initiative

Ʌ To evaluate safety issues in existing automated health care data systems

Ʌ To learn more about the barriers and challenges of this work, both internally and externally

For example, Senior Applications Developer Brita Hedblom is the SME for pharmacy data, while Amundson is a lab data SME and Senior Applications Developer Mary Becker is the utilization and cost data SME. “I want to build out more of the consulting skills of my team,” Paskach says. “The people that we have here really know their stuff, and they love what they do.”

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Statement of activities

Total operating revenue $14,742,000Total investment revenue 388,000Total expenses 13,936,000

Net gain 1,194,000

AssetsCash $6,000Other receivables 80,000Research project receivables 2,032,000Investments 12,039,000Property/equipment 361,000

Total assets 14,518,000

LiabilitiesAccounts payable $1,135,000Prepaid project revenue 165,000

Total liabilities 1,300,000

Net assetsUnrestricted

Undesignated $7,254,000Board-designated 3,310,000

Total unrestricted 10,564,000Temporarily restricted 2,654,000

Total net assets 13,218,000

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Expenses

Operating revenues

HPRF-Sposored Project: 2.8%

Internally Funded Research Projects: 1.7%

Administration and Program Support: 27.1%

Externally Funded Research Projects: 71.1%

HealthPartner General Support: 7.4%

Government-Sponsored Projects: 65.9%

Industry-Sponsored Projects: 9.6%

Contributions: 10.6%

Other: 3.7%

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Marcia Hanson Chair

Debbie Savage Assistant Secretary

Alan Abramson, PhDSVP and CIOHealthPartners

LaMont BoykinsFormer vice-president of training and developmentAmeriprise Financial

Tom BrinskoPresident and CEOYMCA of Greater St. Paul

Jane BrownFormer Executive DirectorSecond Harvest Heartland

Kathy Cooney, MBA, RNExecutive Vice-president and CAOHealthPartners

David Dries, MDSurgeonRegions Hospital

John Finnegan Jr., PhDProfessor and DeanSchool of Public HealthUniversity of Minnesota

Gretchen Leiterman, MBAVice-presidentRegions Hospital Heart Center

Brian Martinson, PhDSenior Research InvestigatorHealthPartners Research Foundation

J. Daniel Nelson, MDAssociate Medical Director HealthPartners Medical Group

Carl Patow, MD, MPHExecutive DirectorHealthPartners Institute of Medical Education

Leif Solberg, MDAssociate Medical Director for Health Care Improvement ResearchHealthPartners

Donna Zimmerman, MPH, RNVice-president of Government and Community RelationsHealthPartners

Brian Rank, MDMedical DirectorHealthPartners Medical Group and Clinics

Andrew Nelson, MPHExecutive DirectorHealthPartners Research Foundation

Tobi Tanzer, JDVice-president of Corporate IntegrityHealthPartners

Barbara Tretheway, JDSr. Vice-president and General CounselHealthPartners

HPRF Board and Committees 2008-2009

Board of Directors and corporate officers

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Research Committee

Joel Holger, MD, chair

Leah Hanson, PhD, vice-chair

Kristin Engebretsen, PharmD

Elie Gertner, MD

Dave Hamlar, MD

Russell Luepker, MD

Deborah Mullen

Cheri Rolnick, PhD

Nancy Sherwood, PhD

Leif Solberg, MD

Howard Stang, MD

Health Services Research

Nancy Sherwood, PhD, chair

Deborah Mullen, vice-chair

Thom Flottemesch, PhD

Mary Martini

Patrick O’Connor, MD

Emily Parker, PhD

Leif Solberg, MD

Marcus Thygeson, MD

Feifei Wei, PhD

Clinical Research

Howard Stang, MD, chair

Kristin Engebretsen, PharmD, vice-chair

Chris Anderson

Sarah Anderson, MD

Steve Asche

Mike Maciosek, PhD

Josh Salzman

Lynette Savaolja, SCT (ASCP)

Gretchen Zunkel, RN, PhD

Michael Zwank, MD

Basic Science Research

Dave Hamlar, MD, chair

Krista Graven, MD, vice-chair

Alex Adams

Thomas Flottemesch, PhD

Erhard Haus, MD, PhD

Suzann Remington, PhD

Institutional Review BoardElie Gertner, MD, chair

Elizabeth Reeve, MD, vice-chair

Imdad Ahmed, MD

Joel Holger, MD

Dave Hamlar, MD

Margaret Krieser, MPH

Mary Jeanne Levitt, MA

Brian Martinson, PhD

Gerda Ottman, PharmD

Julibeth Petter, PhD, RN

Don Postema, PhD

Amar Subramanian, MD

Julie Switzer, MD

Animal Care and Use

Leah Hanson, PhD, chair

Carson Harris, MD, vice-chair

Alex Adams

Dan Brumm, JD

Kate Faltesek, AALAT

Daniel Sadoff, DVM

Linda Sackett-Lundeen

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Contributions to HealthPartners Research Foundation

HealthPartners is an independently incorporated nonprofit organization.

Donations:

Ʌ Support research to improve health care

Ʌ Are tax-deductible

Ʌ Go directly to health care research

Ʌ Can be made through the payroll deduction plan (if you are a HealthPartners employee)

For more information or to make a donation, please contact:

Andrew Nelson, MPH Executive Director, HealthPartners Research Foundation PO Box 1524 8170 33rd Ave. S. Minneapolis, MN 55440 952-967-5001

www.hprf.org

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Don AbbottBrenda L. AbrahamChuck AbrahamsonAlan V. AbramsonAlex AdamsKenneth F. AdamsMohamud M. AdenNkeiru O. AdogaScott A. AebischerKathryn D. AgerbeckImdad AhmedDiane AhoClay AhrensIzabelle K. AilabouniPamela C. AlderinkCalvin U. AllenSusan E. AllenCraig AmundsonPaul AmundsonDaniel M. AndersonJulie AndersonKari AndersonKathleen M. AndersonKimberly AndersonLarin D. AndersonMargaret AndersonPatricia K. AndersonVicki M. AndersonMelody AngellJoyce AngerhoferFelix K. AnkelOnaiza AnsarCecilia AnuforoBabette A. AplandWanda J. AppelmanJeff AppleJason A. ArndtRenae K. ArnevikDavid ArthurStephen E. AscheBetsy A. AsherJohn F. AskelsonElizabeth M. AslesenMelissa AuneConnie AustinErin AustinBeth M. AverbeckDilek Aydinalp-MathewsChiChi AyikaSandeep BahadurPatricia L. BalderClifford W. BallSuzette BanksMarjean C. BarlowKathleen BarrettLori BarrettCynthia BarrickBibi BasdeoCharles Bass

Scott G. BauerCarrie BeadleJennifer BeaudetteAndrea K. BeckerMary T. BeckerSusan J. BeckerRebecca BeilkeRalph BellVianka N. BellGretchen BensonMaria BerensDavid J. BerghSandra BerndtCarolyn C. BesekeHeather M. BettersMichael R. BeugenBarbara A. BeyerBonnie BigelbachJessica BinkleyLisa BirdErik B. BjorakerTed R. BjorkDavid P. BlakeMark F. BlatzheimRhonda J. BleskeyJohn BlomLois BloombergPhilip BoeJessica BoerboomNancy BohlineTamara B. BongWilliam BonkowskeAnne BookJill T. BooksDeborah J. BostrumJill H. BothwellRalph S. BovardSonia M. Bowe-GutmanSheryl BowenElizabeth C. BrackettMary K. BrainerdIrene J. BranumCynthia J. BrattenBeth C. BraunBabette M. BrazielJay A. BrennerDiane A. BresinJane BrinkScott W. BrodersBrad M. BroulikCarolyn BrownPatty BruntjenRichard BruzekKathleen BryanJennifer BryantBeth M. BugosJulie BundeSteve BundeTheresa M. Bunkers-

LawsonDaniel BurnsCarrie A. BuschMaureen BuschChristy BussStacy R. BusseyAmy ButaniDave I. ButaniBarbara L. ButcherMarnie W. ButeJohn ButlerDavid CaccamoMichael CadyTheresa A. CainVicki CallaghanEugenia CanaanLisa R. CapellGail A. CardinalAnnamarie CarleyJoel D. CarlsonKitty CarlsonKimberly CarlsonAndrea CarpentierGregory CarterTerry L. CarterWendy CaseyCentral Pharmacy ServicesKaran L. CerfJennifer M. ChadwickJodi A. ChaffinDanielle A. CharboneauTricia CharbonneauRichard A. ChernKarin ChienEd ChristensenDiana Christensen-

JohnstonMalinda T. ChristopherMichael ChyrklundHeather R. CichanowskiCarmon L. CincoskiMelissa J. CindrichClaims DepartmentAmanda L. ClarkGeorgeann B. ClaudonJennifer ClellandMark ClementsJulie CloutierMary CmielPeter A. ColeGlenn M. ColemanSandra ColgroveDiane M. CollinsGary CollinsLawrence CondonAnn M. ContrerasLynn ConveryPatricia ConzetKathleen M. Cooney

Jonathan M. CooperSusan CooperJeanne CordesCarolyn CorsonNichole CortezEileen CostelloM. Victoria CostelloJill D. CottonAnnette CovingtonAnnisa CrainChristopher R. CrillDiane CronkGaynal CrossTerry CrowsonKathleen A. CummingsDebra CurranLaurel A. CushingRanjan DahiyaSuzanne DahlGregg K. DahlgrenKatie J. DaleSheila M. DalenMichele A. DaleyDiane DaltonLynne A. DanchaJoe DangorKamalini DasAngel R. DavisKevin DavisTami DavisLinda Diane DayTim DeFoeTerese A. DeForDenise DegeJohn DegelauSteven P. DehmerKim DelaneyKim G. DelgadoDebra J. DemosJane DensingerErin DeStasioRita DevangeJulie DevoreRobert DickhausNona M. DietrichJudy A. DilgerMichael V. DiMucciVanessa DiniusLynn DirksSheila DiseRhonda DobakKaren DobbinsJonathan DodgeUsaydor F. DoegarAnn DohrmannWilliam DonaldBill DonovanChristina DowningTerri Draxten

Donors

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Danielle DubackKris P. DudziakPatricia B. DukeMichelle DunnEmily C. DurandDavid A. DziukMatthew EastwoodJohn EatonBruce EdisonMarilyn EelkemaRebecca L. EgelandBarbara EhrlerRochelle EicherChad S. EikenJoan M. EisenzimmerMary ElfmannJanice E. EliasonGreg EllisThomas EllisDoris D. ElstonKevin L. ElyAlice EngelhardtChris EnstadDenise A. EnyiKelley A. EricksonGretchen A. ErieCorinne L. EschChuck EskewMarie A. EvansFlorence FadellLori FakeJaclyn FalkensteinClaire A. FallsHeather l. Farber-LauChristina FarrellRhonda FautchCynthia FayJaclyn FayCraig FeathersConstance L. FeltzOmar D. FernandesNaomi Y. FillmoreJosie J. Fink KoppenBrian FisherJean E. FitchMelissa J. FitzgeraldErika M. FitzPatrickDenise FlahertyJessica R. FlanniganMisty A. FleckColleen E. FletcherForrest M. FlintNicole FlynnJoann ForemanMarilee J. ForsbergKaren C. ForslundAnn Marie FoxMarjory A. FrailichRalph J. Frascone

Kelly FrischKirsten D. FritzeLila Mae FrobergJean FroehlichPatricia FroidStephanie FrostBruce L. GaarderYohannes GabirPatricia GainyoDavid GallagherLisa M. GanserBarbara GarciaMichelle D. GardnerMary C. GarloughKari J. GarmanMulunesh T. GebremichaelChris GeislerSusan L. GentilliJohn P. GerstnerElie GertnerDavid S. GeskoSandra GieferRachel C. GiffordKarley D. GilomenKari A. GirardMartha M. GjerdeDwayne A. GlennBobette GoddingMargaret GoebelRachelle M. GoeltlJoAnn GomerSarah E.A. GonnellaMatthew GoodmanWarren T. GoodmanSally T. GoodsellBradley GordonJoan GorowskyFarhad GouniliLela L. GovindJames GowanDan GowanJacqueline L. GrahamMichelle K. GraunkeKrista K. GravenEleanor J. GravesAmanda F. GregoryMichael J. GriffinPeggy GriffinColleen GriffithKent R. GriffithChristopher T. GrimesRachel A. GroessLisa GroneJoan GruendemanLinda GrummerMaureen GuayKathryn J. GuilfoileHeidi GundersonSusan Gunderson

Sidney C. GuthrieJody J. GuzzoElizabeth GysbersPatricia L. HaackBrett HackBrenda L. HafemannNicole A. HaffelyJeanette M. HagenBetty Jo HaggertyBonnie R. HahnJacquie HakesLeslie D. HakkolaTim HaleyGina HallBruce D. HansenElizabeth A. HansenJohn J. HansenPaul HansenAnn M. HansonJeanne D. HansonLeah R. Hanson,Sharon A. HansonAngela M. HardingJohn T. HardmanLawrence HarmsCynthia HarrisLori A. HarrisMary HarrisAnn HarsteLinda S. HartLinda G. HaselmanRobyn M. HastingsNancy J. HauErhard HausStephanie A. HaverYuki HawkinsPaulette R. HaydenJoy HayesMarcia HayesStephen C. HayesLoretta HaynesHealth Plan Behavioral

HealthHealth Plan Case

ManagementHealth Plan Pharmacy

AdministrationHealthPartners Corporate

CommunicationsWayne HeaserLorraine HechtLora HedinCullen B. HegartyNancy C. HeilleChad C. HeimSusan HeimerlRichard L. HeinrichJudith M. HeintzBrett R. Hendel-PatersonKari Hennen

John W. HeringBruce HermansenIngrid HessJoe HessburgCynthia HeuerKelly HeynMichael HigginsPat HigginsJennifer G. HinesLeslie HingsbergerTheresa Hirte-RuntschMaryellen E. HodgesDavid HodgsonKaren M. HoeschenAnthony HoffPeter B. HofrenningJoel S. HolgerKenneth D. HolmenCathleen A. HolmesPaul F. HoltenSarah HoppeKari R. HougeChad M. HouseRebecca HowardSherri L. HuberKimberly HuebnerJacquelyn A. HuebschChristine L. HultTimothy HuneckeRandolph W. HurleyNancy HusebyRonda Hutchinson-

WatkinsBarbara J. HyerBeatriz A. IbarrondoGretchen M. IbeleFelicia IkebudeMary Lou IrvineBarbara K. IsaacsonKurt IsenbergerGeorge IshamJody M. JacksonIrshad JafriJennifer L. JahangiriChristine JakubowskiAlvina M. JandaCharlotte JanitaAdrienne L. JasinskiRhonda A. JenkinsBruce A. JensenCatharine JensenJudy JerdeAntonio JhocsonCarol JirikBeth JohnsonBruce JohnsonCheryl JohnsonDavid P. JohnsonDavid Johnson

Donors (continued)

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Janine JohnsonJoyce C. JohnsonKathy A. JohnsonLinda JohnsonLinda M. JohnsonMary M. JohnsonCatherine L. Johnson-

ThomsonMarsha JohnstonBetty JonesChrista JonesRebecca M. JonesJim JordanSusie JuddLinda JuettnerJanet JunkmanAngela KaiserNannette KaiserLoree K. KalliainenMichael KaniukJoni K. KappCyril KapsnerBrenda KariStuart KaufmanBurke T. KealeyDawn M. KeenanKaren KellerMary E. KelleyWillard W. KennedyPatrick KennyCheryl KeoghKaykeo Lanoi

KeomanivongTessa KerbyNancy L. KerestesZena M. KhalilMaureen KiekhaferYoung Dae KimDonna KincaidColleen KingDarlynn M. KingThomas M. KingMary KivelJennifer KleinDavid H. KlevanLaurie J. KlossnerJanet KnaresboroJill KnauffKent KnutsonLaurie L. KnutsonNicole C. KohnerJeannette M. KolthoffSusan C. KolzeElaine S. KorschDeanna KossettThomas E. KottkeNorbert KrebsbachSriwan L. KremerSteven G. KremerPatricia Kroska

Violetta KrstichLeslie KucklerCandyce KuehnWilliam R. KuglarPeter G. KumasakaAngelina M. LaisKoffi E. LakpaDeborah A. LaMangeAnne LambertJodi A. LangThomas A. LangeSarah E. LarsenTraci LarsenAndrea L. LarsonAngie LarsonArvin R. LarsonPatricia L. LarsonTodd LarsonScott A. LaskaSue LavigneAnn LazorCarrie LeeHeather E. LeeLawrence H. LeeMichael LeinfelderMaria LeiningerPatti Dalen LeisingerStacie LekoLaurie LenertzSheila LesherSusan M. LeskelaSteve LewandowskiKelly J. LewisTonia LeyhDavid L. LibbyKathleen LibraTimothy LindTim LindquistHelen LineBarbara J. LintonNicole LippertMary Beth LiskaSheila LockhartDeanne L. LoehrTanya R. LoehrLinda LoesKimberley LoilandLisa LordDavid LouisJames M. LovatMaureen C. LoweMarcia LowryAshley LubsBeth LubyJason LuhrsCarol LundstromThuan V. LyCynthia A. LynchJennifer Lysne

Sharon A. MacaulayJohn MacIndoeMichael MaciosekKaren L. MacKenzieMonica MageeCheryl A. Magnuson-GieseRichard MahrLinda A. MakinenRobert M. MalandKaren ManorLinda MapesKaren MargolisJohn MariniSteven MarkesClarice A. MarshPeter MarshallScott B. MarstonCindy MartinDebora S. MartinezBrian MartinsonKatherine B. MartinsonChandra MasloskiNoe B. MateoAvinash MathaJoseph C. MathewsCandace J. MathiasonBrenda MathisCatherine E. MattakatKenta L. May-LewisTheresa C. McBroomCherida I. McCallLinda J. McCallMarian L. McCannGrace D McCarronMaribet McCartyPatrick L. McCauleyNancy A. McClureCharlene E. McEvoyDiane McGuireEileen A. McKennaJulie A. McKnightJoanne McLaughlinCindy McMurrayJean MehlhopCynthia J. MeierElizabeth MelbyGregory S. MellesmoenKaren E. MeloKara MencelAnna Marie MercadoTesfai Y. MerziBobbie MeyenburgPeter J. MeyersThomas MichelsCarol MickelsonJacqueline M. MickelsonCindy MilbrandtConnie R. MillerKristi Miller

Louise MillerMacaela L. MillerRenee MillerKari M. MinerAnne-Marie M. MischelCharles MishekBarbara A. MitchellColleen M. MoeBeth A. MolitorNatalia MonroyKimberly R. MonsonPaul D. MoorePenelope V. MoranChristopher MorkenCathy A. MorrisPatricia MorrisTodd J. MorrisJames MorrisonVicki MortensenLinda G. K. MosesCheryl L. MoultonDerin MuchowEllen M. MuehleggerVita MuggliAnna MulfingerMulti Department Bake

Sale - RHCarol MunteanAmy L. MurhpyAmy L. MurphyIhab H. MurtadaRita G. MurtadaPaul MusherureHolly MyersFreda MyhrwoldShohreh NajmabadikiaKevin N. NakagakiMichael J. NaliBarbara NamenJean NeedhamAndrew F. NelsonChristopher NelsonJ. Daniel NelsonJessie NelsonLaurel A. NelsonMartha A. NelsonRandy NelsonRoxanne NelsonElyse NguyenFrank K. NguyenMichelle NguyenThu-Ha NguyenJoAnn M. NiemiPatricia F. NistlerDenise NolanJames NordinCandice L. Nordling-

LiekhusNathan NorquistNoreen Norton

Donors (continued)

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Craig NotoCarol E. NovakAmy E. NygaardRichard NymoenPaul W. O’ BlackPeter OberstarPatrick O’ConnorJohn OdhiamboKevin OehlerOlubodun OfakunrinGary OftedahlKathy I. OhmannKirsten A. OhnsorgCathleen OhserPaige O’KeefeAaron M. OlsonAllen OlsonChristina OlsonDouglas A. OlsonJoseph R. OlsonJudy A. OlsonJulie OlsonBarbara Olson-BullisElizabeth OnchiriTimothy OrdahlKaren M. OsborneRobert OsterlundGerda OttmanJim OukropDeloris E. OurenAnne L. OwenBrian L. OwensEbonie R. OwensKoken OzdoganBarbara A. OzmunBrian G. PalmerRobert PappasJosh S. ParahEmily D. ParkerJanice ParkerL. Garry ParlierCarl A. PatowDonald D. PattersonGary A. PaulsonPirjo PavelkaPatricia A. PavlakMarie A. PawlitschekPamala A. PawloskiKrista PeakTracy PedersonPamela A. PeineMarilyn PennoyerMikhail PerelmanJoan PerkinsCynthia A. PetersonDarlene M. PetersonErin N. PetersonKelly L. PetersonLyn Peterson

Mary PetersonMaureen S. PetersonTimothy PetersonAnthony PfaffSharon PhilipsonRosemary PhillipsShelley PickettShirley PicquetJoanne PiersonErin H. PipkinBradley J. PitzenBeverly PrawalskyLynne PreeseJohn PribylPatricia PriceNicolaas P. Pronk,Michelle M. ProschSheila ProsperMary Jean ProulxAlecia PuppeBarbara J. QualeSandra QuastRosemary QuirkWilliam H. RabeMark RabinovitchRadiology HSC AdminTim RadkeSteven G. RadosevichKathy RaffertyMohammnad Anis RahmanGoya V. RaikarKaren RaleighLynette RamirezBrian H. RankKimberly A. RapaczKate Rardin-LeahyRuth A. RathbunSherry RawlinsJennifer RechMaria ReedElizabeth A. ReeveRegions Hospital -

Facility Planning & Construction

Claudia ReichkitzerChad ReilSandra S. ReilingCarol A. ReillyKim M. ReinhartMaureen ReinhartJamie ReinschmidtMegan RemarkKatelyn C. ReschetzEllen B. RestSusan RettkeMarylyn ReuterJulie A. RiceMary C. RichardsLori A. RickeAntonio Ricks

Amber RidolfiDaniel M. RiesD. Brad RindalJames RisserRiverview Service CenterShelley Robasse-BishopLaura RobertsonLois RobertsonSusan RochholzDiana RockneRoberta L. RoepkeCollette J. RollSharon J. RolnickJanice RomansJody M. RoodAnn RothPeter R. RotheGail RudbergRob A. RuffStephanie RuotsinojaWilliam RushMary RussellDebra RyanDaniel M. RydelMelissa R. RyderJean RyonLinda Sackett-LundeenEllen SafranskiJohn J. SakowskiCharles W. SalmenJoshua G. SalzmanDoreen M. SampsonRobert SauerCarla SaxenAmy L. SayersKatherine SayreJessica R. SchallockDebra M. SchillerKaren SchirmerDebra SchlosserDebra K. SchmidtJanet L. SchmidtLeslee SchmidtTheresa J. SchneiderSusan SchoeneckerCynthia SchoonoverLee G. SchotzkoBecky SchramskeShellie M. SchreierCharlotte R. SchreinerSandra L. SchrenkAnn SchruppConnie SchugJanette M. SchullMark SchwobLynn ScottMarguerita ScottPamela ScullinDeborah A. Seiberlich

Carol SeifertJonathan S. SellmanShelly SemeradBryan M. SennBob SerreynAnn SettgastNick ShallmanAngela M. ShanleyJason R. SharpeScott A. ShayWendy J. SheridanNancy Sherwood-JohnsonPatricia A. ShowersTerry R. SibbaldPaul SikoraKeri A. SilvernagelMark S. SimmonsWendy J. SimsJerome SiyPaula K. SkardaJoseph W. SkinnerMary SkorczeskiKimberley SlakerJoan SlavenkovMary A. SlavinBarbara J. SmithDona SmithDouglas N. SmithRobert C. SmithSadrina D. SmithStephen SmithNola G. Sokol-WoyakLeif SolbergBrianne SolemDawn SolnitzkyKeri SolsethJudith SomersWilliam N. SorensenCarol A. SoutorJoAnn M. Sperl-HillenMichelle K. StaackJoanne StadlerChristopher StallmanKathy StandingHoward StangChristine R. StansonCaren StaplesBrenda L. StarkJeanne SteffenMonica StefferJennifer J. SteigerwaldSharon SteinJill L. SteinhausNorma SteinmetzBrian StemberCheryl M. StemperAngela StenenTammy StengerLaurie A. Stewart

Donors (continued)

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Sara M. StewartSandra I. StigarJennifer L. StockertMarietta L. StonestromDina StrachotaMiriam StrandMollie E. StromGail D. StrouseLaurie L. SuchanekHelen SullingerMichelle M. SullivanAnnara SundaraKathleen H. SundbergKenneth A. SundbergJeremy J. SundheimSteve SustacekWendy SutterElizabeth SwansonJennifer SwansonGinny R. SwansonKaren P. TaPeter TabakaStephanie A. TaftZain T. TakporA. Lynn TaliaferroStephen TanTobi TanzerRaymonde TappCynthia TaraldsonDanielle T. TateRosane M. TawahFassica B. TefferaMelanie TeskeMelanie D. TharalsonChristopher ThielPatricia ThielenLori ThomBradley ThomasJinie ThomasThomas L. ThulNels Marcus ThygesonTania K. TilpMichael R. TimmMichaela TimmersHenry TindellBarbara TjepkesElizabeth S. TobiasJulian V. TokarevKent V. TormoenDenice TourvillePhilip TraegerMichael A. TrangleBarbara TrethewayLaura L. TrimboJulie A. TrislerJinju S. TruongEric J. TuckNeil J. TurnerKay E. Tuveson

Mustafa UcerVeronica F. ValentinoMarlies T. ValerioJacqueline E. Vallette

UglowSidney E. Van DykeEllen Van KempenTerence L. VanderheidenMee VangSandy VangDeanna D. VarnerElena VassilievaJeffrey G. VigilRenae VillariDeeAnn VinjeMary VogelBob VogesBarbara L. Voit-GloverLynne A. VolkmanGaye C. VollrathThomas von SternbergMelinda WadeAmy WagnerSara WagnerSteven A. WalkerVerley WallenCharmagne WallinAndrea M. WalshAmy WaltonDonna WamstadBev WappelLashazer K. WashingtonJanelle WaslaskiBeth WatermanTed WawrzyniakArlene WebbDorothy WebbTimothy D. WeberGregory WebsterFeifei WeiHeather WeidnerLynn WeisRita WeldonShannon WelshBeth WernerLeann WestMichele WestermanNemera WeyessaJon WhiteRobin WhitebirdSue WhitneySharon L. WiesnerLinda WiitalaLynn M. WilburPeggy L. WillardPam WillenbringDianne J. Willer-SlyJacquelyn WilliamsKaren V. Williams

Lynn WilliamsSandra WilliamsSteve WilsonArthur P. WinemanAmanda L. WingerMichael J. WisemillerElina WivholmAman K. WoldeselassieAaron T. WolfeJessica WoodfordDonald WorleyJim L. WrightKhou XiongKia XiongSheng XiongXee XiongKai XuJennifer YotterRichard J. YoungSandra YoungBarbara J. YoungmarkJeanette L. ZaczkowskiPeter J. ZambranoJanet A. ZanderDennis W. ZhuPaul F ZiemerDonna J. ZimmermanJohn ZimmermanFrank E. ZinkSharon R. Zopfi-JordanGretchen ZunkelMichael Zwank

Donors (continued)

Mission

To discover and accelerate the use of knowledge to improve the health and health care of our members, patients and community.

Vision

To be the premier practice-based research organization for facilitating the transformation of health care and its impact on health.

HealthPartners Research Foundation8170 33rd Ave. S.Minneapolis, MN 55440-1524Phone: 952-967-5001Fax: 952-967-5022

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At HealthPartners Research Foundation, we aim to be good stewards of

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