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High-throughput Sequencer Dec 2011 – 758 sequencers
Apr 2012 – 823 sequencers
Biomedical Research
1 – © 2012 Internet2
Source: http://omicsmaps.com/, Dec. 5, 2011
Increasing at 25% per year
Image: Illumina
Ion Proton Sequencer
Democratization of Sequencing
2 – © 2012 Internet2
Handheld USB Sequencer
Image: Oxford Nanopore Technologies
Image: Life Technologies
Source: L. D. Stein Genome Biol. 11, 207 (2010)
Moving beyond Moore’s Law
3 – © 2012 Internet2
Research Centers Who’s Who
4 – © 2012 Internet2
University VP / CIO
MedicalSchool
CIO
AcademicMedicalCenter
CIO
CancerCenter
CIOGenomics
CenterCIO
• Who does research involving Big Data?
• Who does wide area networking?
• Who talks with whom?• Who is responsible for
security? • Who is collaborative?• Who is in charge?
ESnet Science DMZ for Biomedical Researchers
5 – © 2012 Internet2
Sensitive data– PHI– Limited data set– De-identified
Security– ACLs in DMZ switch– Server hardening– Firewall issues– Encryption– Best practices guide
Source: http://fasterdata.es.net/science-dmz/science-dmz-architecture/
• What do biomedical researchers need today? Tomorrow?• Who are the collaborative early adopters?• How can we disseminate best practices?
– Training the trainer workshops– Educational materials– Performance monitoring and troubleshooting– ESnet’s Science DMZ architecture– Security recommendations
• What is unique in the life sciences?– Security Issues– Transport protocols– International collaborations
Engaging Biomedical Researchers
6 – © 2012 Internet2