1
1 Depa INTR MR pa mappi ing (C this w mappi cantly METH Consid image data ca ly prop ing [3 assum formed as P= coeffic the sp design space equiva straint s U for where zation VARP RESU The pr in a b scanne times. ing, an unders pling p recons separa nique. recons The T higher DISC Severa PCA i and sp physic CONC A new metho REFE [1] Lia pp. 159 1973. p Hig artment of Electrica RODUCTION arametric mappin ng has been limit CS) [2] have show work, we present ng. The proposed reduced imaging HODS der T2 mapping s with variable T an incur severe ar posed reconstruc ][4]. The same a mes (, ) n t ρ = r d from samples o s t UV , where t V cients. Under the arse sampling op ned to determine data is used as alent to solving U ts can effectively r the PS model, a TV(·) represents with continuatio PRO (variable pro ULTS roposed techniqu brain T2 study. T ed at 3T with a s The imaging par nd 256x208 matri sampled at an ac pattern shown in structed with (1) able model [6]; a Figure 2 compa structions using ( 2 map estimated r spatial resolution USSION al sparse samplin is based on the b parsity constraints cally acquired trai CLUSION w image reconstru d shows superior ERENCES ang Z-P, IEEE-ISB 93-1596. [5] Done pp. 413-432, 1973 ghly Accelerat al and Computer E an ng provides quant ted by long scan wn great potential a new method to d method is show g time. as an example, a T2-weightings. W rtifacts in the rec tion methods usi approach can be 1 () ( ) L l l n l u v t = r , w of (, ) n t ρ r such t represents the te e PS model, the m perator and ξ is V t . In Fig.1, we temporal trainin s U . However, dir stabilize the ill-c and the reconstruc s the spatial total on [3][4]. After ρ ojection) [8]. ue, named as PS- The brain of a h spin-echo sequenc rameters are 2s T ix size. The data cceleration factor Fig. 1. The down ) compressed sen and (3) the prop ares the T2 map (1) CS, (2) PS, a from fully samp n and SNR than t ng-based fast para asic PS model an s with V t being e ining data, which uction method ba r performance to e BI 2007. pp. 988-9 eva M, MRM 201 . ed Parameter Engineering, Univ nd Technology, Un titative informati times. Recently, l for accelerating o accelerate para wn to achieve muc and let (, ) n t ρ r With sparse samp onstructed image ng joint PS and s easily adapted fo where L is the m that , ( , mn m ρ = P r emporal subspac measured data ca the measurement e illustrate one sa ng data. With V t rectly determinin conditioned inver ction problem can variation regular (, ) n t ρ r is obtain -Sparse, was vali healthy voluntee ce at 32 different TR, 17.2 ms echo set was retrospec of 10 using the n-sampled data se nsing [5]; (2) pa posed PS-Sparse ps estimated from and (3) the PS-Sp led 32 echoes is the CS and PS co ametric mapping nd suffers from th estimated from a h can more faithfu sed on joint parti existing methods 991. [2] Lustig M, 0. pp. 1114-1120. s ˆ U r Mapping wit Bo Zhao 1,2 , Wenm versity of Illinois a niversity of Illinois on of intrinsic tis sparse sampling g MR data acquis ametric mapping ch more accurate for 1, 2, , n N = L pling, direct inver es and subsequent sparsity constrain or parametric ma model order. Co , ) n t . The PS mo e, and s U repres an be written as t noise. Multiple ampling pattern, being determine g s U from measu rse problem. Spec n be formulated a rization. The abo ed, the desired p idated r was t echo spac- ctively sam- et was artial- tech- m the parse. used as the refer unterparts with th g methods have b he ill-conditionin pre-fixed parame ully capture under ial separability an using a single PS , MRM 2007. pp. [6] Petzschner F, Fig. 2. of 10, r s arg min || = Ω U d th Joint Partia miao Lu 2 , and Zhi- t Urbana-Champa at Urbana-Champ ssue properties, w methods based o sition. Some of th using the PS and e T2 maps than ex , N represents a se rsion of the (k, t tly the T2 map. W nts for acceleratin apping. Specifica onsidering the C del can be equiv ents the correspo s s t ( ) ξ + d FUV e data acquisition in which fully s ed, the reconstru ured data can suff cifically, we use a s, ve convex optim parameter map is rence. As can be he CS showing si been proposed rec ng issue illustrate etric signal mode rlying temporal e nd sparsity constr S or sparsity cons 1182-1195. [3] Zh , MRM 2011. pp. a) Estimated T2 m respectively; b) Er 2 s s t 2 ( ) || + λ Ω FUV al Separability -Pei Liang 1,2 aign, Urbana, IL, U paign, Urbana, IL which are useful b on the theory of p he methods have d sparsity constr xisting methods u et of T2-weighte t)-space measure We have previous ng dynamic imag ally, the PS mode Casorati matrix P valently expressed onding the spatia ξ , where () Ω⋅ is n schemes can be sampled central k uction problem is fer from severe il a spatial finite di mization problem s obtained using seen in Fig. 2 (a ignificant spatial cently, such as th ed in Fig. 2. REP el. The proposed evolution of relax raints has been pr straint for reconst hao B, IEEE-EMB 706-716. [7] Huan maps from CS, PS, rror maps of estima s TV( ) λ U y and Sparsity United States, 2 Be L, United States biomarkers. How partial separable f been extended to raints jointly and using a single PS ed ed s- g- el P d al s e k s ll-conditioning is fference to regula can be efficiently a nonlinear least a), the proposed P blurring and the he k-t PCA meth PCOM uses a sim method uses the xation process. roposed to accele tructing highly un BS 2010. pp. 3390 ng C, MRM 2011 , and PS-Sparse re ated T2 maps usin Fig. 1. A sam Sparse, whic temporal tra pled imagin y Constraints ckman Institute of wever, the utility functions [1] and o parametric map d illustrates its pe or sparsity const sue. Imposing sp arize the inverse y solved by half- t squares fitting p PS-Sparse produc PS low SNR. hod [6] and REPC milar formulation temporal subspa erate MR parame ndersampled data 0-3393. [4] Zhao B . [8] Golub G, SIA constructions at an ng Sparse, PS, and mpling pattern exa ch consists of dens aining data, and sp g data. (1) f Advanced Science of MR parametri compressed sens pping [5][6][7]. I erformance in T2 traint with signifi patial sparsity con problem of fittin -quadratic minimi procedure such a ces a T2 map wit COM [7]. The k- based on joint P ace estimated from etric mapping. Th a. B, IEEE-ISBI 2011 AM J. Numer Ana n acceleration PS-Sparse ample for PS- sely sampled arsely sam- e ic s- n 2- i- n- g i- as h -t S m he 1. l. 2233 Proc. Intl. Soc. Mag. Reson. Med. 20 (2012)

Highly Accelerat ed Parameter Mapping with Joint Partial ...TV( ) Us and Sparsity United States, 2Be, United States iomarkers. How artial separable f been extended to aints jointly

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Page 1: Highly Accelerat ed Parameter Mapping with Joint Partial ...TV( ) Us and Sparsity United States, 2Be, United States iomarkers. How artial separable f been extended to aints jointly

1Depa

INTRMR pamappiing (Cthis wmappicantly METHConsidimagedata caly proping [3

assum

formed

as P =

coefficthe spdesignspace equivastraint

sU for

where zation VARP RESUThe prin a bscannetimes. ing, anunderspling preconsseparanique. reconsThe Thigher DISCSeveraPCA iand spphysic CONCA newmetho REFE[1] Liapp. 1591973. p

Hig

artment of Electrica

RODUCTION arametric mappinng has been limit

CS) [2] have showwork, we present

ng. The proposedreduced imaging

HODS der T2 mapping s with variable Tan incur severe arposed reconstruc][4]. The same a

mes ( , )ntρ =∑r

d from samples o

s tU V , where tV

cients. Under thearse sampling op

ned to determine data is used as

alent to solving Uts can effectively r the PS model, a

TV(·) representswith continuatio

PRO (variable pro

ULTS roposed techniqu

brain T2 study. Ted at 3T with a sThe imaging par

nd 256x208 matrisampled at an acpattern shown in structed with (1)able model [6]; a Figure 2 compa

structions using (2 map estimated

r spatial resolution

USSION al sparse samplinis based on the bparsity constraintscally acquired trai

CLUSION w image reconstru

d shows superior

ERENCES ang Z-P, IEEE-ISB93-1596. [5] Donepp. 413-432, 1973

ghly Accelerat

al and Computer Ean

ng provides quantted by long scan

wn great potentiala new method to

d method is showg time.

as an example, aT2-weightings. Wrtifacts in the rection methods usi

approach can be

1( ) ( )

Ll l nl

u v t=

r , w

of ( , )ntρ r such t

represents the te

e PS model, the mperator and ξ is Vt. In Fig.1, wetemporal traininsU . However, dirstabilize the ill-c

and the reconstruc

s the spatial total on [3][4]. After ρojection) [8].

ue, named as PS-The brain of a hspin-echo sequencrameters are 2s Tix size. The data

cceleration factor Fig. 1. The down

) compressed senand (3) the propares the T2 map(1) CS, (2) PS, afrom fully samp

n and SNR than t

ng-based fast paraasic PS model ans with Vt being eining data, which

uction method bar performance to e

BI 2007. pp. 988-9eva M, MRM 201.

ed Parameter

Engineering, Univnd Technology, Un

titative informatitimes. Recently, l for acceleratingo accelerate para

wn to achieve muc

and let ( , )ntρ r With sparse samp

onstructed imageng joint PS and seasily adapted fo

where L is the m

that , ( ,m n mρ=P r

emporal subspac

measured data cathe measurement

e illustrate one sang data. With Vt rectly determininconditioned inverction problem can

variation regular( , )ntρ r is obtain

-Sparse, was valihealthy volunteece at 32 different

TR, 17.2 ms echo set was retrospecof 10 using the

n-sampled data sensing [5]; (2) paposed PS-Sparse ps estimated fromand (3) the PS-Spled 32 echoes is the CS and PS co

ametric mappingnd suffers from thestimated from a h can more faithfu

sed on joint partiexisting methods

991. [2] Lustig M,0. pp. 1114-1120.

sU

r Mapping witBo Zhao1,2, Wenm

versity of Illinois aniversity of Illinois

on of intrinsic tissparse sampling

g MR data acquisametric mappingch more accurate

for 1, 2, , n N= L

pling, direct inveres and subsequentsparsity constrainor parametric ma

model order. Co

, )nt . The PS mo

e, and sU repres

an be written as t noise. Multipleampling pattern,

being determineg sU from measu

rse problem. Specn be formulated a

rization. The aboed, the desired p

idated r was t echo spac-

ctively sam-

et was artial-tech-

m the parse. used as the referunterparts with th

g methods have bhe ill-conditioninpre-fixed parame

ully capture under

ial separability anusing a single PS

, MRM 2007. pp. [6] Petzschner F,

Fig. 2. of 10, r

s

arg min ||= − ΩU

d

th Joint Partiamiao Lu2, and Zhi-t Urbana-Champaat Urbana-Champ

ssue properties, wmethods based o

sition. Some of thusing the PS and

e T2 maps than ex

,N represents a sersion of the (k, ttly the T2 map. Wnts for acceleratinapping. Specifica

onsidering the C

del can be equiv

ents the correspo

s s t( ) ξ= Ω +d F U V

e data acquisitionin which fully s

ed, the reconstruured data can suffcifically, we use as,

ve convex optimparameter map is

rence. As can be he CS showing si

been proposed recng issue illustrateetric signal moderlying temporal e

nd sparsity constrS or sparsity cons

1182-1195. [3] Zh, MRM 2011. pp.

a) Estimated T2 mrespectively; b) Er

2s s t 2( ) || + λΩ F U V

al Separability-Pei Liang1,2 aign, Urbana, IL, Upaign, Urbana, IL

which are useful bon the theory of phe methods have d sparsity constrxisting methods u

et of T2-weightet)-space measureWe have previousng dynamic imag

ally, the PS mode

Casorati matrix P

valently expressed

onding the spatia

ξ , where ( )Ω ⋅ isn schemes can besampled central kuction problem isfer from severe ila spatial finite di

mization problem s obtained using

seen in Fig. 2 (aignificant spatial

cently, such as thed in Fig. 2. REPel. The proposed evolution of relax

raints has been prstraint for reconst

hao B, IEEE-EMB706-716. [7] Huan

maps from CS, PS,rror maps of estima

sTV( ) λ U

y and Sparsity

United States, 2BeL, United States

biomarkers. Howpartial separable f

been extended toraints jointly andusing a single PS

ed ed s-g-el

P

d

al

s e k s ll-conditioning isfference to regula

can be efficientlya nonlinear least

a), the proposed Pblurring and the

he k-t PCA methPCOM uses a sim

method uses the xation process.

roposed to acceletructing highly un

BS 2010. pp. 3390ng C, MRM 2011

, and PS-Sparse reated T2 maps usin

Fig. 1. A samSparse, whictemporal trapled imagin

y Constraints

ckman Institute of

wever, the utility functions [1] and o parametric map

d illustrates its pe or sparsity const

sue. Imposing sparize the inverse

y solved by half-t squares fitting p

PS-Sparse producPS low SNR.

hod [6] and REPCmilar formulation

temporal subspa

erate MR paramendersampled data

0-3393. [4] Zhao B. [8] Golub G, SIA

constructions at anng Sparse, PS, and

mpling pattern exach consists of densaining data, and spg data.

(1)

f Advanced Science

of MR parametricompressed sens

pping [5][6][7]. Ierformance in T2traint with signifi

patial sparsity conproblem of fittin

-quadratic minimiprocedure such a

ces a T2 map wit

COM [7]. The k-based on joint P

ace estimated from

etric mapping. Tha.

B, IEEE-ISBI 2011AM J. Numer Ana

n acceleration PS-Sparse

ample for PS-sely sampled arsely sam-

e

ic s-n

2-i-

n-g

i-as

h

-t S m

he

1. l.

2233Proc. Intl. Soc. Mag. Reson. Med. 20 (2012)