Homecare Dialysis Solutions

Global Trends Don’t Reflect the CKD Reality

The age for Stage 5 CKD is falling , as the overall profile of Diabetes and Hypertension suffers falls.

China will change the CKD map

Estimated that China = 4x US CKD suffers120 million in China with CKD1.5 million on dialysisForecast to double to 3 million by 2022

Cost differential in China between Clinic is smaller due to lower Medical costs, but expected to raise to a more western model of care

Dialysis treatment is Clinic Focused and Expensive

• Ireland = 166,603 dialysis sessions per annum • Cost of €73,139 million • (2- 3 % of the total Healthcare budget)

• Patients require 3 sessions per week = 156 p.a. • Cost average, €439.00 per session

• Cost In Clinic Haemodialysis €41,250.00 p.p.p.a. • Cost Average Haemodialysis €68,484.00 p.p.p.a. (clinic/

meds / doctors & support / transport )

• COST OF Home Dialysis €22-25,000 per person p.a.

Total No. of Renal Treatment Patients - Ireland

Transplant 54.5%

Haemodialysis, 39.3%

Peritoneal 6.2%

3960 Patients

Home €25K p.a. Vs Clinic/Hospital 75K p.a.

1. Begin day

4. Dialysis treatment and acquiring intra-dialysis data

3. Take responsibility for patients and pre dialysis data (PPC)

6. Post-dialysis data

7. Release patients

8. Find the back hometransport

Clinic Dialysis = 6-9 Intensive Hours / Day

2. Organize the transport to clinic

Home Dialysis : Solving the platform puzzle !

The Health Provider Reduce costs & better

dialysis results

The Patient & Family

To enjoy a Longer and better quality of life via HHD you need first to

convince them to leave , manage transition & maintain wellbeing.

The Manufacturer Better, more

compelling product & develop client loyalty.

Nephrologists & Hospitals

Better & more effective patient & data management

Researchers Stream of highly

precise and valuable data

TelecomsConnected data

Call Centre Service

We Know the Benefits Of Home Dialysis

• Lower Cost• Lower Stress• Reduced Meds• Flexible Plan• Personalised Plan• Health Benefits (Tax

& Earnings)• Work Benefits (Tax

& Earnings)• Holiday Benefits

The Challenge is Getting them There

• To meet chronic capacity & cost constraints, governments in the OECD need to shift at least 20% of all clinic based dialysis patients to their homes over the next 10 years. Getting & keeping them there is the challenge

• Some Home dialysis is happening – but very dependent on Clinician skills and resources. • Most Healthcare provider – reach a plateau get only the most motivated patients into the

home• An objective, consistent, professional & automated system is required to empower and

encourage more patients into the home regardless of what machine they use

The aim of this support tool is to first train patients in home dialysis through our unique applied solution

Once they are in their home support them in the management of their home dialysis.

We are seeking to collaborative and work directly with organisations and partnering institutions (Tyndall) to scale our solution to transform chronic healthcare management from

the clinic to the home.

Support Training & Increase Transfer To home

Education TrainingMonitoring

& Risk Evaluator

Patient Assessment &

rating

P1 -Home Therapy Trainer – Digital Process

• Increase Home Transfer rate - Pre-dialysis training• Ireland – min 20% regardless of local staffing resources

• HDSolutions market research of patients as id 5 categories we are confident of at least 20% take-up of home dialysis with proper training and support)

• Reduce HSE overhead for ESKD management ( est.50%-66%)

• Measure - Attitudes, Emotions & Difficulties• Implement -Staff & Patients & other modifications

• Test - Effectiveness/usability of the HDSolutions Digital P1 training

• Prototype solution on the 3 categories of test subjects; • A - Nurse, B - Patient & C - Caregiver.

P2 – Home Therapy Manager

Empowered Patient in

their home

(KT/V)2

Phosphates

DIET PROGRAM STRESS DIALYSIS INFORMATION DIALYSIS TIME

• Once in the Home give better analysis into the patients hands

Empowering people to manage their condition better • External monitoring – overcoming distance anxiety

System Architecture

• It delivers at level of cost to the Health provider substantially lower than the present alternative

• Increases efficient and deal with the emerging capacity crunch in the management of this chronic condition

• It is being developed manufactured and will be exported from Ireland.

P1 Trainer - Summary• Machine Self Use Training • Nurse Monitoring of Patient Home Training- Risk Evaluation• Patient Monitoring of their Home Training- Risk Evaluation• Nurse Monitoring of Home Help Training• Home Yes /No check list evaluator. • Home System management (water filtering machine, secured

power supply)

HSE Engagement-To-Date:• Agreement Clinical Director – National Renal Office Test-Trial

• University Hospital Cork• Waterford University Hospital

• Costing and support for Testing Trial – €155,000-175,000 – €25,000 commitment from HSE budgets – Richard Corbridge

ForecastPhases Phase 1

14 monthsPhase 2

10 monthsPhase 3

12 monthsPhase 4

12 monthsPhase 5

12 monthsInvestment

Requirement€610,000* €900,000* €900,000 €600,000 €600,000

Scope MVP & Trial*Not including €150,000 seed funding & feasibility analysis

Rollout HSE/NHS- Ireland- UK

Rollout EU- Germany- Italy- Portugal- Switzerland

Rollout US & Asia- USA- Japan- Taiwan- Hong

Kong- Shanghai

Rollout Middle East- UAE- Qatar- Saudi

Arabia- Bahrain

Clients (Compounded)

10 74 (+64) 215 (+141) 503 (+288) 809 (+396)

Deliverables Product Dev.Testing & TrialIP Buyout/Reg.Medical Contacts Centre (MCC) 

Sales & Marketing rolloutExpansion InfrastructureExpand MCC

Expansion into EUScale up ESKD management

Expansion into US and Japan, Tiawan, HK Scale up ESKD iv management

Expansion into UAE. Scale up ESKD iv management

Software Roadmap

Ver1.0 Ver1.1 Ver1.2 Ver2.0 Ver2.1

Revenue €0 €1,491,100 €3,283,450 €6,670,435 €9,929,701Profits -€588,704 €60,092 €594,137 €2,625,367 €4,521,338

By the end of phase 2 - €1,510,000 has been invested and the business is cash positive. Subsequent investment , are not reflected in the forecast,Option at the end of Phase 21. engage with a strategic industry partner e.g. Baxter Health care, exit and ‘sell’ the project- deliver a modest return between €9 &10 million. (Gross

Earnings X 6)2. undertake a third round of build & evolved product in the EU & US market. -Phase 3-5.

Application Sales Earning breakdownP1 Trainer Software •(Once Off) Main Hospital Unit License €25.000 X 1 (Basic Package)*

€25,000.00•Per Patient Annual License €1.100 X 30 =

€33,000.00•Yearly SW upgrade €2.500 =

€2,500.00•SW trainer consultant € 850 per day X 30 Days PA =

€25,500.00•*(Advanced Package add 50%)

P2 Home Manager Software •Per Patient Annual License €1.100 X 30 =

€33,000.00•SW trainer consultant € 850 per day X 30 Days PA =

€25,500.00•Per Patient Annual License € 400.00 X 30 =

€12,000.00

Total Year 1 BM Hospital €168,000.00•Recurring License Revenue PA Per 30 HHD persons

€ 66,000.00•Recurring Consultants Revenue PA Per 30 HHD persons

€ 30,000.00(Based upon 1 day per patient)

Total Recurring € 96,000.00•Set Up /One Off. Earnings Per Patient

€5,600.00•Recurring Earnings Per HHD Patient PA

€3,200.00

Developing Strategy

Irish National Health Irish Medical Trail Partners

Developing StrategyMario NegriItalian Medical Trail Partner

Hospital NiguardaItalian Medical Trail partner

Dialysis Hardware Partner

PolitechnicoMilano

Trial Partners

Software Platform Partner

HMI Partner

Thank You.