T he 2011 Friends of the Stehlin

Foundation gala turned into a wish fulfilled for the gala chairs, Donna Lewis, Lin Mills Smolensky, and Nancy White– three board members and Friends who had chaired events in the past.

The theme for the evening was

“We Hope You Dance,” and the crowd most certainly DID– while being treated to another festive evening in true Stehlin style.

Headline act Lee Ann Womack rocked the hall with her back-to-back hits, especially the Grammy-award-winning theme song “I Hope You Dance.” For the 500 people who attended the event in the Westin Galleria ballroom, it was a chance to enjoy this world-renowned singer in an intimate concert setting.

Bidding was fast and furious at the silent and live auctions. Anna Williams Parker assembled an appealing list of items ranging from deluxe vacations, including a week at the luxurious Los Suenos Resort provided by A Stay in Costa Rica and a one-week Wine Country trip sponsored by Spec’s Wines, Spirits, and Finer Foods to unique pieces of designer jewelry from Valobra Jewelry and Marla’s Gem Creations.

The crowd, dressed in “black-tie and dancin’ boots” finery, took full advantage of the photo booth and were treated during dinner to an energized performance by the U.S. Open West Coast Swing Champions and music by Back at the Ranch.

After Lee Ann Womack’s performance, popular dance band Doppelganger took over and kept the dance floor full until the wee hours.

All in all, the 31st annual Friends gala was another successful event, netting more than $300,000 to be donated to the CHRISTUS Stehlin Foundation for Cancer Research to advance critical cancer studies.

Bobby Anderson, president of CHRISTUS Stehlin, said, “Dr. John Stehlin emphasized the importance of hope for his patients and their families. At this stage of our research, we have great hopes for the future.

T H E C H R I S T U S S T E H L I N F O U N D A T I O N F O R C A N C E R R E S E A R C H A P R I L 2 0 1 2

HOPE was in the Air

Lee Ann Womack

Dear Friends,We hoped you would dance – and you did until 1 a.m.!

We hoped you would enjoy – and that was evident

by smiles and laughter around the auction table, at the

photo booth and visiting with friends. We hoped you would join in advancing the

Foundation’s pioneering research efforts to bring better

treatments to those with cancer – and you did with your

financial generosity, auction donations and commitment

to service. And now, we thank you for sharing our evening of

Hope. Thank you for packing the Westin ballroom, dancing

to Lee Ann Womack and Doppelganger, and bidding

on our terrific silent and live auction items. We thank the

Friends of the Stehlin Foundation for their support and help

in making this 2011 Gala a success. The dedication and hard work of many supporters,

especially during these tough economic times, is evident

by the $338,000 that the Friends were able to contribute

to the CHRISTUS Stehlin Foundation for Cancer Research.

Our hearts are filled with gratitude, joy and, most of

all, HOPE.

2011 Gala ChairsDonna LewisLin Mills SmolenskyNancy White

Left to right, 2011 Gala Chairs Lin Mills Smolensky, Nancy White and Donna Lewis

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2011GALASCRAPBOOK

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And Yet Another Reason for Hope!Great news – planning for the 2012 Friends of the

Stehlin Foundation gala has already begun!

Gabrielle Patout, Kim Robinson and Lory Tauber have signed on as this year’s energetic co-chairs –

and the excitement is starting to build.

Once again, longtime Friends supporters Danny Ward, Nancy Ames and Nancy Riviere secured the services of a world class entertainer

along the lines of past headliners Dionne Warwick, Marvin Hamlisch, The Temptations, The Beach Boys, Robert Earl Keene and Lee Ann Womack.

Great News!! With a Grammy Award winner selected as the 2012 performer (name to be revealed at the Gala Preview Party!!!), we can

confidently say you won’t be disappointed! Mark your calendars!

The 32nd Friends of the Stehlin Foundation Gala

Saturday, November 10, 2012

Westin Galleria Ballroom

7:00 pm

2012 Gala Chairs Kim Robinson, Gabrielle Patout and Lory Tauber

Major Benefactor

Mrs. Charline Dauphin

Benefactor

The Congregation of the Sisters of Charity of the Incarnate Word, Houston

Shall We Dance

Luci Bonneau Striking Against Breast Cancer

Lorrie and Earl Magee

Just Dance

The Ellwood FoundationBeverly PevehouseMrs. Annette Scranton

Burn the Floor

CHRISTUS Foundation for Healthcare

CHRISTUS HealthAbraham D. Garza, Jr. – in honor of

Conception Garza MontezInsperityLisa and John LentsGinger and Terry RathertMrs. Denise Rosenfeld

Dance Fever

Andrea Montgomery DesignsCabot Oil & Gas CorporationCinco Energy ServicesGE Oil & Gas, Drilling and Surface

Wendy and Beppino GiovanellaHouston Contract InteriorsDonna and Norman LewisThe Marek FamilyRiviana Foods, Inc.

Flashdance

Nathalie and Bastiaan de ZeeuwSylvia and Roupen DekmezianKathi Mosbacher and Mike WheelerJeanette and Jim Woods

Boot Scootin’

Alief Feed Store, Inc.Jacki and Brian EvansFive Star Metals, Inc.Sally and David HarvinJanet and Elton Lipnick –

in honor of Dr. Peter de IpolyiMichelle and Constantine MarkidesMasraff’s RestaurantCathey and Michael MeagherSport Court of Texas

Last Tango

Colliers InternationalEdge Creative Strategies, LLCFrost BankArlene and Alan GergerMr. Jeffrey GobeliVeronica and Dana GompersSallie Gordon and Kenneth SchwenkePenny and Tom HaberMr. Thomas JacksonWanda S. Kimbrell, CPA

Teresa and John LangstonKim and Jeff LittleDanna and Hal LyndeMarla’s Gem CreationsMartha Turner PropertiesMarilyn and John McGillBud and Karen NajvarDr. Ethan and Kathy NatelsonKaren and Harvey Newton /

Morgan Stanley Smith BarneyJan and Tom PhippsSara Reddy, M.D.Sheila and Jim RickertWilliam SaroskyJenny and Sam TavorJerri and David TriggKaren and Charlie WalkerBarbara and Steve WirickEva Wolski BlackAdrienne and David Zugheri

Footloose

Ellie and Nathan BaneMrs. Betty BellamyMarion and Chuck BesmehnC & G Repair, Inc.Mr. Paul CagleCarole and Eugene Chambers

FoundationChase LimoJyl and Chris CashionChilton Capital ManagementFaye and Michael CoplandMs. Callie DaciiLynne and Gordon FindlayMs. Sharon C. Graham

Gray MechanicalMs. Janet HillHolders Pest ControlKathryn and John HollerInterconnect Enterprises, Inc.Janitor’s WarehouseHelen JenswoldThe Keep On Trucking Company, Inc.Mr. and Mrs. Donald KramerLawana and Richard KunzeWinnefred LesandriniDr. and Mrs. Kenneth Eugene LehrerMrs. Joachim LiehrThe Martin CompaniesPatty and Keith MillerAnn and Harvey OylerMr. and Mrs. Joe M. PeddyEmmet Perry & Co. Fine Carpets

and RugsPinetree, Inc.Louise and Jim PluttRaven MechanicalMeredith and Michael RiceSimplex GrinnellMary and Harry SmithMs. Sydney StaleyMary C. StehlinJanet and Richard StupekB. Craig ThomsonBeverly and Larry VavraM. L. Vincent Jr. & AssociatesMr. and Mrs. Matthew D. WinterVicki and Fred WrightVWR International, LLCMelinda and Jon Young

13 CelsiusA & M PhotoAccent on Travel /

Leah Smolensky TignerAlexander’s Fine Portrait DesignNancy Ames and Danny WardSally and Bobby Anderson Andrea Montgomery DesignsAristaArtemis Hair StudioBeaver’s Ice HouseBlakely BeringBlankietBrennan’s of HoustonCardinal BoutiqueCarnival Cruise Line /

Deborah ThompsonMike Carr Chama Gaucha Brazilian SteakhouseChappelletDonna Conners / Striking Against

Cancer Bowling TournamentSydney ContinoContraband HatsCorinthia Hotel LondonSylvia DekmezianDelta Air LinesLinda de Sosa / Woodlake TravelDominic Walsh Dance TheatreElaine Turner DesignsElegant Events and Catering

by Michael

Emmet Perry & Co. Fine Carpets and Rugs

Finishing Touches @ Norris of Houston

Jill Ford ConsultingFour Seasons Hotel HoustonFour Seasons Hotel Las VegasCarolyn GarciaDr. Annette GempJonathan R. Gingell, D.C.Gloria Ferrer Caves and VineyardsGolfTECHaak Vineyards and WineryRoberta HarrisRobert HarrisonHenderson DesignsHotel Esencia / Damari RubioHouston City ClubHouston Contract InteriorsHouston Grand OperaHouston Southwest VendorsAustin James / Thornwood GalleryJenny Tavor CateringJordan Vineyard and Winery Kapscandy Family VineyardPat KelleyKim KellyKerzner International Bahamas LTDRobert LanziniDonna LewisLIFE + DOGLos Sueños Resort and MarinaMariquita Masterson

Julie Mastroianni Bill MeekMessina Hof WineryMaxine MuellerMary Nichols Sueanne NicholsNorris of Houston Salon and Day SpaMarla Omer / Marla’s Gem CreationsJoel OppenheimDavid Peck CollectionAbigal Peterson Pine Forest Country ClubProcare ART TherapyElain RaichleMary Riggs RamainSharee and Dana Robertson Rocky Carroll Boot CompanyNat RoseJanis RossRoy EstatesMargaret Runion Chef Michele SalakBecky SartainSavannah HouseSensia Studio and Japanese Day SpaCharles SheffieldEmmitt J. Smith Bill SmolenskyLin Mills SmolenskyLindsey SmolenskySpec’s Wines, Spirits and Finer FoodsSydney Staley StarFlite Aviation

StatoilStay in Costa Rica / Larry SavageStella and Dot / Ali Santano, Director

and Founding LeaderWilliam W. StubbsStudio NiaMovesSugar Creek InteriorsSunburst Beach Vacationst’afia / Monica PopeTeknionDeborah L. ThompsonLeah Smolensky Tigner Timex CorporationTony Mandola’sTootsiesJerri and David TriggUnited AirlinesThe Urban VineValobra JewelryWater 2 WineHeather WestendarpThe Westin Galleria, HoustonThe Westin St. Francis, San FranciscoNancy White Betty Whiteside Clark Whiteside Neil WilkinsLee Ann WomackMichele Wood Yellowfin Ocean SportsZ.D. Winery

2011 Gala Auction Donors

2011Gala Contributors

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New Board Member Victoria L. Brown, Ph.D.

With 25 years of progressive research and managerial experience, Dr.

Victoria Brown is a valued addition to the CHRISTUS Stehlin Foundation Board of Trustees.

Dr. Brown joined CHRISTUS Health this past September as the System Director, Clinical Research Administration, after several years as a program director and research manager for the Tobacco Research and Treatment Program at The University of Texas M.D. Anderson Cancer Center. She has been conducting research, including animal studies, community-based studies, and clinical trials, since receiving her doctorate in pharmacology in 1997.

Prior to joining the board, Dr. Brown visited the CHRISTUS Stehlin labs, where she was impressed by the “focused and serious” work done by the researchers – as a team, “with no heroes.” As a “back to basics” person herself, she appreciated the elegant solutions pioneered by the Stehlin group, including using something as simple as heat to

optimize anticancer treatment several decades ago.

Most importantly, Victoria Brown felt an emotional response to the nude mice she witnessed at the laboratory, realizing that they represented the type

of tumors growing often unbeknownst to people with cancer. “I reached another level of understanding about how critical compounds like CZ48 can be,” she said.

Dr. Brown officially joins the board this spring. Welcome!

Dr. Beppino Giovanella, Dr. Victoria Brown and Bobby Anderson at the CHRISTUS Stehlin Foundation.

2012 GALA PREVIEW PARTY

The annual Friends of the Stehlin Foundation gala is held to raise money to fund the Foundation’s various important research projects. We invite you to get involved with this year’s event and

learn about the Friends of the Stehlin Foundation.

Join us at the Fundraising and Kick-Off Eventfor the 2012 Friends of the Stehlin Foundation Annual Gala

Date: Thursday April 12, 2012Time: 7-10 p.m.

Location: The Wynden (formerly Masraff’s)Address: 1025 South Post Oak Lane · Houston, TX 77056

RSVPs must be received by April 9. Please email ccolton@stehlin.org or call 713-659-1336.

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By age 50, one of every two men worldwide will show microscopic evidence of prostate cancer. The

disease has become the most common cancer diagnosed in American men, representing fully one-third of all newly-diagnosed malignancies.

But before new therapeutic strategies can be developed, scientists must understand each cancer’s biology, the mechanism involved in its progression, and its diversity.

Until now, prostate cancer research has been hampered by a shortage of tumor models. The National Cancer Institute’s Prostate Cancer Progress Review Group urged the development of new cell lines, saying, “New models will provide methods of testing both chemopreventative and chemotherapeutic agents. Moreover, novel therapeutic protocols, such as

gene therapy and immunotherapy, can be tested.”

Paving the Way for More Research and Treatment

In a three-year, $1.5 million project, CHRISTUS Stehlin Foundation researchers are teaming with physicians at Baylor College of Medicine to create the first comprehensive repository of human prostate cancer tumor cell lines and xenografts.

The cell lines and grafts will represent all prostate cancer subtypes and prognoses: from primaries to metastases, indolent to aggressive.

The lines are being developed by Stehlin scientists from tumor tissue samples harvested by Baylor physicians during prostatectomies or metastatic

STEHLIN RESEARCH NEWS

Stehlin and Baylor Join Forces for Prostate Research

Chemotherapy section supervisor Tony Kozielski

opens a cryrostorage unit containing human cancers

stored in liquid nitrogen.

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Grant Enables Critical Prostate Cancer Study

The CHRISTUS Stehlin Foundation was recently awarded a major grant from the

Vivian L. Smith Foundation in support of prostate cancer research.

Smith Foundation trustees voted to approve the three-year grant in November following a site visit to the CHRISTUS Stehlin laboratory. The Vivian L. Smith Foundation has been a generous supporter of the Stehlin Foundation for many years.

The grant has been earmarked for the collaborative project with Baylor College of Medicine to develop a broad line of prostate cancer cell lines and xenografts to be made available to researchers the world over.

(see full story adjacent)

Want to read more about research underway at the CHRISTUS Stehlin Foundation? Visit our website at stehlin.org – and check back often! You’ll find news, details about upcoming events, our photo gallery and lots of information about what we are doing to improve the lives of people with cancer.

CHRISTUS Stehlin as Library Builder

The prostate cell model project is not the first of its kind for the Foundation. Thirty-five years ago, Stehlin researchers established the first significant number of breast cancer tumor cell lines, which led to an explosion in breast cancer therapeutics. Stehlin’s breast cancer work also resulted in a collaboration with Dr. Dennis Slamon – and the development of Herceptin®, an effective anticancer drug against certain aggressive breast cancers. Today more than half of all breast cancer tumor cells used around the world originated in the Stehlin lab.

In addition to prostate cancer studies, CHRISTUS Stehlin researchers are compiling a library of cell lines and xenografts for DSRCT, a highly aggressive sarcoma cancer that strikes children and young adults. The cell model project should spark new research into this rare and deadly disease.

continued on page 7

CZ48, a promising new anticancer drug developed at the

CHRISTUS Stehlin Foundation, is currently undergoing Phase I human clinical trials at the UT Health Science Center at San Antonio and the University of New Mexico Cancer Center.

Patients who qualify for the study are all suffering from advanced cancers and have failed conventional treatments such as surgery, chemotherapy, and radiation.

The purpose of Phase I is to determine the safety of the drug by administering initially small dosages with gradual escalations. The results to date are promising: after 3, 6, 7, and 8 months of treatment respectively, four of these critically ill patients have demonstrated stable disease (little or no progression). Side effects have been mild and manageable.

Drug Delivery Improvements

While progress is being made on the clinical trials, Stehlin

scientists back at the lab continue to develop new formulations and discover ways to deliver CZ48 more effectively. As an example, Stehlin researchers are working with labs around the world to decrease the size of the drug particles, enabling them to be delivered to and absorbed by the cancer cells more rapidly.

STEHLIN RESEARCH NEWS

Stehlin and Baylor Join Forces for Prostate Research

Human cancers growing as cell cultures in the

Stehlin laboratory

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Prostate Research continued

lesion biopsies. As more tumor xenografts and cell lines are established, researchers can better describe the defining characteristics of the disease, both as a whole and within each subclass of tumors.

The project team is making the materials available to the worldwide scientific community, which will spark new research into the causes and treatment of the disease.

The project is multi-disciplinary, requiring data from and providing it to all parts of the prostate cancer landscape. Its goal is to translate findings quickly and efficiently “from research bench to bedside,” or from laboratory experiments through clinical trials to actual point-of-care patient applications.

According to Stehlin laboratory director, Dr. Beppino Giovanella, “It is very exciting to be on the leading edge of this neglected field of study,

which affects 1 in 6 American males. We expect our work to generate a boost in research, and, eventually more effective treatments.”

CZ48 Clinical Trials Continue

Of Interest

Stehlin board member Gordon Findlay (blue shirt)

presents a donation of $58,000 to the CHRISTUS

Stehlin Foundation for Cancer Research team including

Robert Anderson, Constantine Markides, PhD, and

Dana Vardeman. Findlay’s group, Golfers Against

Cancer, chose the Stehlin Foundation as its first

recipient in 1997, and has been a constant supporter

for 15 consecutive years.

CHRISTUS Health Moves Offices to Dallas No Change for CHRISTUS Stehlin Foundation

In January 2012, CHRISTUS Health, the corporate sponsor of

the CHRISTUS Stehlin Foundation, announced that they would consolidate their Houston and San Antonio offices at a new corporate headquarters in Irving, Texas.

As a result 700-800 Houston corporate employees will move to the Dallas area. However, the company will keep its Houston hospitals and ministry employees.

The decision will have no effect on the CHRISTUS Stehlin Foundation. “We expect to maintain the same close ties we have always had with CHRISTUS Health,” summarized Bobby Anderson, president of the Foundation.

In 2006, the Stehlin Foundation became part of CHRISTUS Health, an international faith-based nonprofit healthcare system comprised of more than 50 hospitals and long-term care facilities, 175 clinics and outpatient centers, and dozens of other health ministries. The CHRISTUS system is affiliated with the Sisters of Charity of the Incarnate Word, a Catholic congregation of women that has supported the Foundation since 1970.

Board of Trustees

Mr. KiM Wheless

Houston, Texaschairman of the board

Mr. Michael Meagher

Houston, Texasvice chairman

Dr. Victoria BroWn

Houston, Texas

Mr. george conKlin

Houston, Texas

Dr. Peter De iPolyi

Houston, Texas

Mr. a. gorDon FinDlay, Jr.Kingwood, Texas

Dr. John gillean

Irving, Texas

Dr. BePPino gioVanella

Houston, Texas

Mr. John hine

Houston, Texas

Mr. rayMonD Khoury

Houston, Texas

Mrs. Donna leWis

Houston, Texas

Dr. ethan natelson

Houston, Texas

sister rosanne PoPP, M.D.Houston, Texas

Dr. Michael ross

Houston, Texas

Dr. thoMas royer

Irving, Texas

Ms. lin Mills sMolensKy

Houston, Texas

Dr. John stehlin, Jr.Houston, Texas

Mrs. nancy White

Houston, Texas

Visit

the cHRISTUS stehlin FounDation

on the internet at

www.stehlin.org

10301 Stella Link, Suite AHouston, TX 77025713-659-1336www.stehlin.org

Address Service Requested

NONPROFITORGANIZATION

U.S. POSTAGE PAID

Houston, TXPermit No. 2146

S tehlin laboratory technician Lauren Battershell is a veteran marathon runner, as is her father Darryl Moore,

who lives in Fort Worth, Texas. In fact, with a lifetime goal of completing a marathon in every state by his 60th birthday, Darryl Moore has 23 marathons to his credit, including four of his local Cowtown Marathons.

His running career was in doubt when Darryl Moore was diagnosed last May with gastric adenocarcinoma, or stomach cancer. Obviously, the family was heartbroken over the diagnosis.

It was over the Christmas holidays, after two rounds of chemotherapy, that Darryl expressed his disappointment that he couldn’t compete in his #5 Cowtown Marathon and earn his fifth finisher’s medal “point,” to complete the race’s unique star display plaque.

Lauren initially wondered if she had the strength, but she proposed her idea anyway: “I asked my dad how he felt about me pushing him the 26.2 miles in a wheelchair so he could get his star.”

While the two never trained together, Lauren worked out with extra weights over

the next months to build strength for the 11 lb. wheelchair and her 155 lb. dad. Her parents bought a streamlined wheelchair that would make going uphill a bit easier – although Lauren says going downhill poses its own kind of challenges.

A Hilly Course

With hope and smiles, on February 26, Lauren and Darryl started the hilly course in Fort Worth – and completed it in 5 hours and 59 minutes. Surprisingly, Darryl felt well enough to run the last two-tenths of a mile, and across the finish line, on his own!

The best win of all? As of February 17, Darryl Moore has been declared in remission from his bout with cancer.

In the week after the race, Lauren was sore, sore, sore. Her dad announced that his 24th marathon was by far “his easiest!”

It is stories like this that bring the work of the CHRISTUS Stehlin Foundation for Cancer Research down to a personal level. Congratulations, Lauren and Darryl – way to go the distance!

Stehlin Staffer Goes the Extra Mile

Stehlin laboratory technician Lauren Battershell and her father Darryl Moore competed in the Cowtown Marathon on February 26.

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